{"id":10144,"date":"2018-06-08T01:00:00","date_gmt":"2018-07-27T09:44:27","guid":{"rendered":"http:\/\/www.05921.net\/index.php\/2018\/07\/27\/%e8%8b%8f%e5%b7%9e%e5%8c%bb%e5%b7%a5%e6%89%80%e5%9c%a8%e5%89%8d%e5%88%97%e8%85%ba%e7%99%8c%e6%96%b0%e8%87%b4%e7%99%8c%e5%9f%ba%e5%9b%a0%e7%9a%84%e7%a0%94%e7%a9%b6%e4%b8%ad%e5%8f%96%e5%be%97%e8%bf%9b\/"},"modified":"2018-07-27T17:44:28","modified_gmt":"2018-07-27T09:44:28","slug":"%e8%8b%8f%e5%b7%9e%e5%8c%bb%e5%b7%a5%e6%89%80%e5%9c%a8%e5%89%8d%e5%88%97%e8%85%ba%e7%99%8c%e6%96%b0%e8%87%b4%e7%99%8c%e5%9f%ba%e5%9b%a0%e7%9a%84%e7%a0%94%e7%a9%b6%e4%b8%ad%e5%8f%96%e5%be%97%e8%bf%9b","status":"publish","type":"post","link":"https:\/\/www.05921.net\/index.php\/10144\/","title":{"rendered":"\u82cf\u5dde\u533b\u5de5\u6240\u5728\u524d\u5217\u817a\u764c\u65b0\u81f4\u764c\u57fa\u56e0\u7684\u7814\u7a76\u4e2d\u53d6\u5f97\u8fdb\u5c55"},"content":{"rendered":"<div class=\"bpp-post-content\">\n<p><img class=\"\"       style=\"\" 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style=\"\">\u3000\u3000\u6b64\u5916\uff0c\u76f8\u5173\u6210\u679c\u5df2\u7533\u8bf7\u4e13\u5229\uff1a\u4eba\u524d\u5217\u817a\u764c\u65e9\u671f\u8bca\u65ad\u7528\u957f\u94fe\u975e\u7f16\u7801RNA\u5e8f\u5217\u53ca\u5176\u5e94\u7528\u3002\u4e13\u5229\u7533\u8bf7\u53f7\uff1a201710992491.6\uff0c\u76ee\u524d\u5df2\u7533\u8bf7\u516c\u5e03\u3002<\/p>\n<p style=\"\">\u3000\u3000\u57fa\u4e8ePCSEAT\u7684\u8868\u8fbe\u4f5c\u4e3a\u533a\u5206\u6b63\u5e38\u524d\u5217\u817a\u7ec4\u7ec7\u4e0e\u524d\u5217\u817a\u764c\u7ec4\u7ec7\u7684\u65b9\u6cd5\u5177\u6709\u975e\u5e38\u9ad8\u7684\u7279\u5f02\u6027\u548c\u654f\u611f\u6027\uff0c\u8be5\u9879\u4e13\u5229\u5177\u6709\u975e\u5e38\u9ad8\u7684\u5e94\u7528\u524d\u666f\uff0c\u5176\u5e94\u7528\u80fd\u663e\u8457\u63d0\u9ad8\u524d\u5217\u817a\u764c\u8bca\u65ad\u7684\u7cbe\u51c6\u5ea6\uff0c\u964d\u4f4e\u524d\u5217\u817a\u764c\u60a3\u8005\u8bca\u6cbb\u8d39\u7528\u3002<\/p>\n<p style=\"\">\u3000\u3000\u8be5\u7814\u7a76\u5de5\u4f5c\u83b7\u5f97\u4e86\u4e2d\u79d1\u9662\u767e\u4eba\u8ba1\u5212\u3001\u4e2d\u79d1\u9662\u524d\u6cbf\u79d1\u5b66\u91cd\u70b9\u7814\u7a76\u9879\u76ee\u3001\u56fd\u5bb6\u91cd\u70b9\u7814\u53d1\u8ba1\u5212\u548c\u56fd\u5bb6\u81ea\u7136\u57fa\u91d1\u7684\u8d44\u52a9\u3002<\/p>\n<p style=\"\">\u3000\u3000\u8bba\u6587\u4fe1\u606f\uff1aXiaohui Yang, Liang Wang, Rong Li, Yuhui Zhao, Yinmin Gu, Siying Liu, Tianyou Cheng, Kuohsiang Huang, Yi Yuan, Dalong Song, Shan Gao*. The long non-coding RNA PCSEAT exhibits an oncogenic property in prostate cancer and functions as a competing endogenous RNA that associates with EZH2, May.4, 2018 (Published online).&nbsp;<\/p>\n<p style=\"\">\u3000\u3000\u8bba\u6587\u94fe\u63a5<\/p>\n<p style=\"\"><img class=\"\"     style=\"border-width: 0px;border-style: none;border-color: initial;vertical-align: top;max-width: 500px;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/07\/beepress2-1532684668.jpeg\" alt=\"\u82cf\u5dde\u533b\u5de5\u6240\u5728\u524d\u5217\u817a\u764c\u65b0\u81f4\u764c\u57fa\u56e0\u7684\u7814\u7a76\u4e2d\u53d6\u5f97\u8fdb\u5c55\" title=\"\u82cf\u5dde\u533b\u5de5\u6240\u5728\u524d\u5217\u817a\u764c\u65b0\u81f4\u764c\u57fa\u56e0\u7684\u7814\u7a76\u4e2d\u53d6\u5f97\u8fdb\u5c55\"  \/><\/p>\n<p style=\"\">\u3000\u3000\u56fe1 ROC\u66f2\u7ebf\u8bc4\u4f30\u4ee5PCSEAT\u7684\u8868\u8fbe\u4f5c\u4e3a\u533a\u5206\u6b63\u5e38\u7ec4\u7ec7\u4e0e\u524d\u5217\u817a\u764c\u7ec4\u7ec7\u7684\u65b9\u6cd5\uff1a\u4ee5PCSEAT\u7684\u8868\u8fbe\u4f5c\u4e3a\u533a\u5206\u6b63\u5e38\u524d\u5217\u817a\u7ec4\u7ec7\u4e0e\u524d\u5217\u817a\u764c\u7ec4\u7ec7\u7684\u65b9\u6cd5\u663e\u793a\u51fa\u4e86\u76f8\u5f53\u5927\u7684\u9884\u6d4b\u610f\u4e49\uff0c\u5176\u7ebf\u4e0b\u9762\u79ef\uff08area under the curve \uff0cAUC)\uff09\u8fbe\u5230\u4e860.950\u3002<\/p>\n<p style=\"\"><img class=\"\"     style=\"border-width: 0px;border-style: none;border-color: initial;vertical-align: top;max-width: 500px;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/07\/beepress0-1532684668.jpeg\" alt=\"\u82cf\u5dde\u533b\u5de5\u6240\u5728\u524d\u5217\u817a\u764c\u65b0\u81f4\u764c\u57fa\u56e0\u7684\u7814\u7a76\u4e2d\u53d6\u5f97\u8fdb\u5c55\" title=\"\u82cf\u5dde\u533b\u5de5\u6240\u5728\u524d\u5217\u817a\u764c\u65b0\u81f4\u764c\u57fa\u56e0\u7684\u7814\u7a76\u4e2d\u53d6\u5f97\u8fdb\u5c55\"  \/><\/p>\n<p style=\"\">\u3000\u3000\u56fe2 CTG\u5b9e\u9a8c\u68c0\u6d4bGSK343\u5904\u7406\u5bf9\u6572\u4f4ePCSEAT\u540e\u7684PC3\u7ec6\u80de\u7684\u589e\u6b96\u80fd\u529b\u7684\u5f71\u54cd\uff1a\u4e0e\u5bf9\u7167\u7ec4\u7ec6\u80de\u76f8\u6bd4\uff0c\u6572\u4f4ePCSEAT\u4f1a\u5bfc\u81f4\u524d\u5217\u817a\u764c\u7ec6\u80dePC3\u5bf9EZH2\u6291\u5236\u5242GSK343\u7684\u6297\u6027\u589e\u5f3a\uff0c\u8fd9\u8868\u660ePCSEAT\u7684\u8868\u8fbe\u53ef\u4ee5\u4f5c\u4e3a\u4e34\u5e8a\u4e0a\u68c0\u6d4bEZH2\u6291\u5236\u5242\u6548\u5e94\u7684\u751f\u7269\u6807\u5fd7\u7269\u3002<\/p>\n<p style=\"\"><img class=\"\"     style=\"border-width: 0px;border-style: none;border-color: initial;vertical-align: top;max-width: 500px;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/07\/beepress5-1532684668.jpeg\" alt=\"\u82cf\u5dde\u533b\u5de5\u6240\u5728\u524d\u5217\u817a\u764c\u65b0\u81f4\u764c\u57fa\u56e0\u7684\u7814\u7a76\u4e2d\u53d6\u5f97\u8fdb\u5c55\" title=\"\u82cf\u5dde\u533b\u5de5\u6240\u5728\u524d\u5217\u817a\u764c\u65b0\u81f4\u764c\u57fa\u56e0\u7684\u7814\u7a76\u4e2d\u53d6\u5f97\u8fdb\u5c55\"  \/><\/p>\n<p style=\"\">\u3000\u3000\u56fe3 PCSEAT\u4fc3\u8fdb\u524d\u5217\u817a\u764c\u7ec6\u80de\u589e\u6b96\u3001\u8fc1\u79fb\u7684\u5206\u5b50\u673a\u7406\uff1aPCSEAT\u53ef\u4ee5\u901a\u8fc7\u7ade\u4e89\u7ed3\u5408miR-143-3P\u548cmiR-24-2-5P\uff0c\u6b63\u5411\u8c03\u63a7\u9776\u57fa\u56e0EZH2\u7684\u8868\u8fbe\uff0c\u8fdb\u800c\u4fc3\u8fdb\u764c\u7ec6\u80de\u589e\u6b96\u3001\u8fc1\u79fb\uff1b\u5176\u8fd8\u53ef\u4ee5\u901a\u8fc7\u5916\u6ccc\u4f53\u5206\u6ccc\u81f3\u80de\u5916\uff0c\u5e76\u88ab\u4e34\u8fd1\u53d7\u4f53\u7ec6\u80de\u6444\u53d6\uff0c\u4ece\u800c\u4fc3\u8fdb\u76f8\u5e94\u7ec6\u80de\u7684\u589e\u6b96\u548c\u8fc1\u79fb\u3002<\/p>\n<\/p>\n<blockquote class='keep-source'>\n<p>\u59cb\u53d1\u4e8e\u5fae\u4fe1\u516c\u4f17\u53f7\uff1a                         \u57fa\u56e0\u8c37                      <\/p>\n<\/blockquote>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>\u524d\u5217\u817a\u764c\u662f\u7537\u6027\u6700\u5e38\u89c1\u7684\u6076\u6027\u80bf\u7624\uff0c\u4e5f\u662f\u5bfc\u81f4\u764c\u75c7\u60a3\u8005\u6b7b\u4ea1\u7684\u4e3b\u8981\u539f\u56e0\u4e4b\u4e00\u3002\u5168\u4e16\u754c\u6bcf\u5e74\u6709\u8d85\u8fc7110\u4e07\u7684\u65b0\u589e\u524d\u5217\u817a\u764c\u60a3\u8005 [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":10145,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[2],"tags":[],"_links":{"self":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/10144"}],"collection":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/comments?post=10144"}],"version-history":[{"count":1,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/10144\/revisions"}],"predecessor-version":[{"id":10150,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/10144\/revisions\/10150"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/media\/10145"}],"wp:attachment":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/media?parent=10144"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/categories?post=10144"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/tags?post=10144"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}