{"id":10238,"date":"2018-06-14T01:00:00","date_gmt":"2018-07-27T09:45:35","guid":{"rendered":"http:\/\/www.05921.net\/index.php\/2018\/07\/27\/nature%e5%ad%90%e5%88%8a%e6%8f%ad%e7%a7%98%ef%bc%9a%e4%b8%87%e8%83%bd%e6%8a%97%e7%99%8c%e5%9f%ba%e5%9b%a0%e7%9a%84%e7%a7%98%e5%af%86%e6%ad%a6%e5%99%a8\/"},"modified":"2018-07-27T17:45:36","modified_gmt":"2018-07-27T09:45:36","slug":"nature%e5%ad%90%e5%88%8a%e6%8f%ad%e7%a7%98%ef%bc%9a%e4%b8%87%e8%83%bd%e6%8a%97%e7%99%8c%e5%9f%ba%e5%9b%a0%e7%9a%84%e7%a7%98%e5%af%86%e6%ad%a6%e5%99%a8","status":"publish","type":"post","link":"https:\/\/www.05921.net\/index.php\/10238\/","title":{"rendered":"Nature\u5b50\u520a\u63ed\u79d8\uff1a\u201c\u4e07\u80fd\u201d\u6297\u764c\u57fa\u56e0\u7684\u201c\u79d8\u5bc6\u6b66\u5668\u201d"},"content":{"rendered":"<div class=\"bpp-post-content\">\n<section  class=\"\" style=\"font-size: 16px;white-space: normal;max-width: 100%;text-align: justify;letter-spacing: 0.476px;background-color: rgb(255, 255, 255);color: rgb(62, 62, 62);font-family: \u5fae\u8f6f\u96c5\u9ed1;box-sizing: border-box !important;word-wrap: break-word !important;\">\n<section class=\"\" style=\"max-width: 100%;border-width: 0px;border-style: none;border-color: initial;box-sizing: border-box !important;word-wrap: break-word !important;\">\n<section class=\"\" style=\"max-width: 100%;border-width: 0px;border-style: none;border-color: initial;box-sizing: border-box !important;word-wrap: break-word !important;\">\n<section class=\"\" style=\"padding: 0.8em;max-width: 100%;border-width: 1px 0.4em;border-style: solid;border-color: rgb(172, 29, 16);border-radius: 0.3em;box-sizing: border-box !important;word-wrap: break-word !important;\">\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;word-wrap: break-word !important;\">p53\u662f\u4e00\u79cd\u80bf\u7624\u6291\u5236\u57fa\u56e0\uff0c\u8be5\u57fa\u56e0\u7684\u5931\u6d3b\u5bb9\u6613\u589e\u52a0\u80bf\u7624\u53d1\u5c55\u7684\u98ce\u9669\u3002\u8fd1\u65e5\uff0c\u6765\u81ea\u6fb3\u5927\u5229\u4e9a\u4e00\u7ec4\u79d1\u5b66\u5bb6\u53d1\u73b0\uff0c\u5728\u4eba\u4f53\u6b63\u5e38DNA\u4fee\u590d\u8fc7\u7a0b\u4e2d\u8d77\u4f5c\u7528\u7684\u4e00\u7ec4\u7279\u6b8a\u57fa\u56e0\u5bf9p53\u7684\u6709\u6548\u6027\u81f3\u5173\u91cd\u8981\u3002\u8fd9\u4e00\u65b0\u4fe1\u606f\u53ef\u4ee5\u5e2e\u52a9\u533b\u751f\u66f4\u597d\u5730\u8bc6\u522b\u67d0\u4e9b\u764c\u75c7\u98ce\u9669\uff0c\u5e76\u6709\u52a9\u4e8e\u4e3a\u60a3\u8005\u5f00\u53d1\u66f4\u5b89\u5168\u3001\u6709\u6548\u7684\u6cbb\u7597\u65b9\u6cd5\u3002<span style=\"max-width: 100%;color: rgb(0, 0, 0);box-sizing: border-box !important;word-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<p style=\"text-align: center;\"><br  \/><\/p>\n<p style=\"text-align: center;\"><img class=\"\"     style=\"margin-top: 6px;margin-bottom: 6px;border-width: 0px;border-style: none;border-color: initial;vertical-align: middle;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/07\/beepress5-1532684736.jpeg\" alt=\"Nature\u5b50\u520a\u63ed\u79d8\uff1a\u201c\u4e07\u80fd\u201d\u6297\u764c\u57fa\u56e0\u7684\u201c\u79d8\u5bc6\u6b66\u5668\u201d\" title=\"Nature\u5b50\u520a\u63ed\u79d8\uff1a\u201c\u4e07\u80fd\u201d\u6297\u764c\u57fa\u56e0\u7684\u201c\u79d8\u5bc6\u6b66\u5668\u201d\"  \/><\/p>\n<p style=\"text-align: center;\"><span style=\"color: rgb(136, 136, 136);\">Professor Andreas Strasser, associate professor Marco Herold and Dr. Ana Janic from the Walter and Eliza Hall Institute. Credit: The Walter and Eliza Hall Institute<\/span><\/p>\n<p style=\"text-align: center;\"><span style=\"color: rgb(136, 136, 136);\"><br  \/><\/span><\/p>\n<p style=\"text-align: justify;\">6\u670811\u65e5\uff0cNature Medicine\u6742\u5fd7\u4ee5\u201cDNA repair processes are critical mediators of p53-dependent tumor suppression\u201d\u4e3a\u9898\u53d1\u8868\u4e86\u8fd9\u9879\u7814\u7a76\u7684\u6700\u65b0\u7ed3\u679c\uff0c Walter and Eliza Hall \u7814\u7a76\u6240\u7684Ana Janic\u4e3a\u7b2c\u4e00\u4f5c\u8005\uff0cMarco Herold\u548cAndreas Strasser\u4e3a\u5171\u540c\u901a\u8baf\u4f5c\u8005\u3002<\/p>\n<p><br  \/><\/p>\n<p style=\"text-align: center;\"><img class=\"\"     style=\"margin-top: 6px;margin-bottom: 6px;border-width: 0px;border-style: none;border-color: initial;vertical-align: middle;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/07\/beepress6-1532684736.png\" alt=\"Nature\u5b50\u520a\u63ed\u79d8\uff1a\u201c\u4e07\u80fd\u201d\u6297\u764c\u57fa\u56e0\u7684\u201c\u79d8\u5bc6\u6b66\u5668\u201d\" title=\"Nature\u5b50\u520a\u63ed\u79d8\uff1a\u201c\u4e07\u80fd\u201d\u6297\u764c\u57fa\u56e0\u7684\u201c\u79d8\u5bc6\u6b66\u5668\u201d\"  \/><\/p>\n<p style=\"text-align: center;\"><span style=\"color: rgb(136, 136, 136);\">DOI\uff1ahttps:\/\/doi.org\/10.1038\/s41591-018-0043-5<\/span><\/p>\n<p><br  \/><\/p>\n<p style=\"text-align: justify;\">\u201c\u4e16\u754c\u4e0a\u4e00\u534a\u7684\u764c\u75c7\u662f\u7531\u4e8ep53\u6ca1\u6709\u53d1\u6325\u5e94\u6709\u7684\u4f5c\u7528\u800c\u53d1\u751f\u7684\u3002\u867d\u7136\u7814\u7a76\u4eba\u5458\u65e9\u5c31\u610f\u8bc6\u5230p53\u7684\u91cd\u8981\u6027\uff0c\u4f46\u662f\u8fc4\u4eca\u4e3a\u6b62\u8fd8\u6ca1\u6709\u4eba\u80fd\u591f\u89e3\u91ca\u8fd9\u79cd\u86cb\u767d\u8d28\u662f\u5982\u4f55\u963b\u6b62\u764c\u75c7\u53d1\u5c55\u7684\u3002<\/p>\n<section class=\"\"  style=\"max-width: 100%;color: rgb(51, 51, 51);\">\n<section style=\"margin: 10px auto;max-width: 100%;text-align: center;box-sizing: border-box !important;word-wrap: break-word !important;\">\n<section style=\"margin-bottom: 3px;margin-left: 33px;max-width: 100%;font-size: 0px;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 16px;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"margin-bottom: 10px;max-width: 100%;width: 6px;height: 6px;display: inline-block;color: rgb(255, 255, 255);background-color: rgb(172, 29, 16);box-sizing: border-box !important;word-wrap: break-word !important;\"><\/span><span style=\"max-width: 100%;display: inline-block;width: 10px;height: 10px;opacity: 0.6;color: rgb(255, 255, 255);background-color: rgb(172, 29, 16);box-sizing: border-box !important;word-wrap: break-word !important;\"><\/span>&nbsp;&nbsp;&nbsp;<\/span><\/section>\n<section style=\"margin-top: -2px;max-width: 100%;font-size: 0px;box-sizing: border-box !important;word-wrap: break-word !important;\">\n<section style=\"max-width: 100%;display: inline-block;width: 15px;height: 15px;border-width: 1px;border-style: solid;border-color: white;opacity: 0.9;vertical-align: bottom;color: rgb(255, 255, 255);background-color: rgb(172, 29, 16);box-sizing: border-box !important;word-wrap: break-word !important;\"><\/section>\n<section style=\"max-width: 100%;display: inline-block;border-width: 1px;border-style: solid;border-color: rgb(255, 255, 255);width: 30px;height: 30px;line-height: 30px;vertical-align: top;color: rgb(255, 255, 255);background-color: rgb(172, 29, 16);box-sizing: border-box !important;word-wrap: break-word !important;\">\n<p class=\"\" style=\"margin-right: auto;margin-left: auto;max-width: 100%;min-height: 1em;white-space: pre-wrap;min-width: 1px;font-size: 16px;box-sizing: border-box !important;word-wrap: break-word !important;\">01<\/p>\n<\/section>\n<section style=\"max-width: 100%;display: inline-block;width: 15px;height: 15px;border-width: 1px;border-style: solid;border-color: white;opacity: 0.9;vertical-align: top;color: rgb(255, 255, 255);background-color: rgb(172, 29, 16);box-sizing: border-box !important;word-wrap: break-word !important;\"><\/section>\n<\/section>\n<section style=\"margin-top: 3px;margin-left: -33px;max-width: 100%;font-size: 0px;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 16px;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;display: inline-block;width: 10px;height: 10px;opacity: 0.6;color: rgb(255, 255, 255);background-color: rgb(172, 29, 16);box-sizing: border-box !important;word-wrap: break-word !important;\"><\/span><span style=\"margin-bottom: -10px;max-width: 100%;width: 6px;height: 6px;display: inline-block;color: rgb(255, 255, 255);background-color: rgb(172, 29, 16);box-sizing: border-box !important;word-wrap: break-word !important;\"><\/span>&nbsp; &nbsp;<\/span><\/section>\n<\/section>\n<\/section>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);text-align: center;\"><span style=\"max-width: 100%;font-size: 16px;color: rgb(123, 12, 0);box-sizing: border-box !important;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;text-align: justify;box-sizing: border-box !important;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"text-align: justify;\">\u53d1\u73b0p53\u7684\u6291\u764c\u673a\u5236<\/span><\/strong><\/span><\/strong><\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><span style=\"max-width: 100%;font-size: 16px;color: rgb(123, 12, 0);box-sizing: border-box !important;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;text-align: justify;box-sizing: border-box !important;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"text-align: justify;\"><br  \/><\/span><\/strong><\/span><\/strong><\/span><\/p>\n<p style=\"text-align: justify;\">\u201c\u6211\u4eec\u7684\u7814\u7a76\u9996\u6b21\u89e3\u91ca\u4e86p53\u662f\u5982\u4f55\u9884\u9632\u764c\u75c7\u751f\u957f\u7684\uff0c\u201d Janic\u535a\u58eb\u8bf4\uff0c \u201c\u5728\u8fd9\u9879\u4ee4\u4eba\u5174\u594b\u4e14\u524d\u6240\u672a\u6709\u7684\u7814\u7a76\u4e2d\uff0c\u6211\u4eec\u89c2\u5bdf\u5230\uff0cDNA\u4fee\u590d\u57fa\u56e0<strong>MLH1<\/strong>\u7b49\uff08Msh2, Rnf144b, Cav1\u53caDdit4\u57fa\u56e0\uff09\u5bf9p53\u9632\u6b62<strong>B\u7ec6\u80de\u6dcb\u5df4\u7624<\/strong>\u53d1\u5c55\u7684\u80fd\u529b\u81f3\u5173\u91cd\u8981\u3002\u201d<\/p>\n<p><br  \/><\/p>\n<p style=\"text-align: justify;\">\u63ed\u793aMLH1\u662fp53\u5bf9\u6297\u764c\u75c7\u7684\u5173\u952e\u6b66\u5668\u53ef\u4ee5\u5e2e\u52a9\u533b\u751f\u66f4\u65e9\u5730\u8bca\u65ad\u764c\u75c7\uff0c\u4ece\u800c\u5236\u5b9a\u51fa\u66f4\u5b89\u5168\u3001\u66f4\u6709\u9488\u5bf9\u6027\u7684\u6cbb\u7597\u65b9\u6848\u3002<\/p>\n<p><br  \/><\/p>\n<p style=\"text-align: justify;\">\u201c\u4f8b\u5982\uff0c\u5982\u679c\u4e00\u4e2a\u75c5\u4eba\u7684\u6dcb\u5df4\u7624\u4ea7\u751f\u4e86\u4e00\u4e2a\u7a81\u53d8\uff0c\u4f7fDNA\u4fee\u590d\u673a\u5236\u5931\u6548\uff0c\u90a3\u4e48\u533b\u751f\u53ef\u4ee5\u907f\u514d\u67d0\u4e9b\u635f\u4f24DNA\u7684\u6cbb\u7597\u624b\u6bb5\uff0c\u4f8b\u5982\u5316\u7597\uff0c\u56e0\u4e3a\u8fd9\u53ea\u4f1a\u4f7f\u764c\u75c7\u66f4\u5177\u653b\u51fb\u6027\u3002\u201d<\/p>\n<p><br  \/><\/p>\n<p style=\"text-align: justify;\">Janic\u535a\u58eb\u8fdb\u4e00\u6b65\u6307\u51fa\uff1a\u201c\u660e\u767d\u4e86MLH1\u548c\u5176\u4ed6DNA\u4fee\u590d\u56e0\u5b50\u7684\u91cd\u8981\u6027\u540e\uff0c\u6211\u4eec\u53ef\u4ee5\u5f00\u59cb\u5bfb\u627e\u65b9\u6cd5\uff0c\u4ee5\u627e\u51fa\u5b83\u4eec\u7684\u7f3a\u5931\u53ef\u80fd\u5bf9\u6cbb\u7597\u764c\u7ec6\u80de\u9020\u6210\u7684\u6f0f\u6d1e\uff0c\u8fdb\u800c\u5229\u7528\u8fd9\u4e9b\u6f0f\u6d1e\u6765\u83b7\u5f97\u6cbb\u7597\u6548\u76ca\u3002\u201d<\/p>\n<section class=\"\"  style=\"max-width: 100%;color: rgb(51, 51, 51);\">\n<section style=\"margin: 10px auto;max-width: 100%;text-align: center;box-sizing: border-box !important;word-wrap: break-word !important;\">\n<section style=\"margin-bottom: 3px;margin-left: 33px;max-width: 100%;font-size: 0px;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 16px;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"margin-bottom: 10px;max-width: 100%;width: 6px;height: 6px;display: inline-block;color: rgb(255, 255, 255);background-color: rgb(172, 29, 16);box-sizing: border-box !important;word-wrap: break-word !important;\"><\/span><span style=\"max-width: 100%;display: inline-block;width: 10px;height: 10px;opacity: 0.6;color: rgb(255, 255, 255);background-color: rgb(172, 29, 16);box-sizing: border-box !important;word-wrap: break-word !important;\"><\/span>&nbsp;&nbsp;&nbsp;<\/span><\/section>\n<section style=\"margin-top: -2px;max-width: 100%;font-size: 0px;box-sizing: border-box !important;word-wrap: break-word !important;\">\n<section style=\"max-width: 100%;display: inline-block;width: 15px;height: 15px;border-width: 1px;border-style: solid;border-color: white;opacity: 0.9;vertical-align: bottom;color: rgb(255, 255, 255);background-color: rgb(172, 29, 16);box-sizing: border-box !important;word-wrap: break-word !important;\"><\/section>\n<section style=\"max-width: 100%;display: inline-block;border-width: 1px;border-style: solid;border-color: rgb(255, 255, 255);width: 30px;height: 30px;line-height: 30px;vertical-align: top;color: rgb(255, 255, 255);background-color: rgb(172, 29, 16);box-sizing: border-box !important;word-wrap: break-word !important;\">\n<p class=\"\" style=\"margin-right: auto;margin-left: auto;max-width: 100%;min-height: 1em;white-space: pre-wrap;min-width: 1px;font-size: 16px;box-sizing: border-box !important;word-wrap: break-word !important;\">02<\/p>\n<\/section>\n<section style=\"max-width: 100%;display: inline-block;width: 15px;height: 15px;border-width: 1px;border-style: solid;border-color: white;opacity: 0.9;vertical-align: top;color: rgb(255, 255, 255);background-color: rgb(172, 29, 16);box-sizing: border-box !important;word-wrap: break-word !important;\"><\/section>\n<\/section>\n<section style=\"margin-top: 3px;margin-left: -33px;max-width: 100%;font-size: 0px;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 16px;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;display: inline-block;width: 10px;height: 10px;opacity: 0.6;color: rgb(255, 255, 255);background-color: rgb(172, 29, 16);box-sizing: border-box !important;word-wrap: break-word !important;\"><\/span><span style=\"margin-bottom: -10px;max-width: 100%;width: 6px;height: 6px;display: inline-block;color: rgb(255, 255, 255);background-color: rgb(172, 29, 16);box-sizing: border-box !important;word-wrap: break-word !important;\"><\/span>&nbsp; &nbsp;<\/span><\/section>\n<\/section>\n<\/section>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);text-align: center;\"><span style=\"max-width: 100%;font-size: 16px;color: rgb(123, 12, 0);box-sizing: border-box !important;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;text-align: justify;box-sizing: border-box !important;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"text-align: justify;\">\u89e3\u6790MLH1\u7684\u8be6\u7ec6\u529f\u80fd<\/span><\/strong><\/span><\/strong><\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><span style=\"max-width: 100%;font-size: 16px;color: rgb(123, 12, 0);box-sizing: border-box !important;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;text-align: justify;box-sizing: border-box !important;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"text-align: justify;\"><br  \/><\/span><\/strong><\/span><\/strong><\/span><\/p>\n<p style=\"text-align: justify;\">\u8fd9\u4e9b\u53d1\u73b0\u8fd8\u8bc1\u660e\u4e86\u8fdb\u884c\u8be6\u7ec6\u529f\u80fd\u5206\u6790\u7684\u91cd\u8981\u6027\u3002\u201c\u6211\u4eec\u7b5b\u9009\u4e86300\u591a\u4e2ap53\u4e0b\u6e38\u9776\u70b9\uff0c\u4ee5\u786e\u5b9a\u54ea\u4e9b\u57fa\u56e0\u5bf9p53\u7684\u80bf\u7624\u6291\u5236\u529f\u80fd\u5f88\u91cd\u8981\u3002Herold\u535a\u58eb\u89e3\u91ca\u5230\uff0c\u4ee4\u4eba\u60ca\u8bb6\u7684\u662f\uff0cDNA\u4fee\u590d\u57fa\u56e0MLH1\u7684\u7f3a\u5931\u963b\u6b62\u4e86p53\u6b63\u5e38\u529f\u80fd\u7684\u53d1\u6325\uff0c\u4ece\u800c\u5bfc\u81f4\u6dcb\u5df4\u7624\u7684\u53d1\u5c55\u3002\u800c\u5f53MLH1\u88ab\u653e\u56de\u53cd\u5e94\u65b9\u7a0b\u5f0f\uff08equation\uff09\u4e2d\u65f6\uff0c\u80bf\u7624\u53d1\u5c55\u660e\u663e\u505c\u6ede\u3002\u201d<\/p>\n<p><br  \/><\/p>\n<p style=\"text-align: justify;\">Herold\u535a\u58eb\u8bf4\uff1a\u201c\u6e05\u695a\u6574\u4e2aDNA\u4fee\u590d\u673a\u5236\u5bf9p53\u9884\u9632\u764c\u75c7\u53d1\u5c55\u81f3\u5173\u91cd\u8981\uff0c\u8fd9\u5c06\u4fc3\u4f7f\u6211\u4eec\u7ee7\u7eed\u63a2\u7d22\u5176\u4ed6\u7684DNA\u4fee\u590d\u57fa\u56e0\u3002\u201d<\/p>\n<p style=\"text-align: justify;\"><br  \/><\/p>\n<section class=\"\"  style=\"max-width: 100%;color: rgb(51, 51, 51);\">\n<section style=\"margin: 10px auto;max-width: 100%;text-align: center;box-sizing: border-box !important;word-wrap: break-word !important;\">\n<section style=\"margin-bottom: 3px;margin-left: 33px;max-width: 100%;font-size: 0px;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 16px;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"margin-bottom: 10px;max-width: 100%;width: 6px;height: 6px;display: inline-block;color: rgb(255, 255, 255);background-color: rgb(172, 29, 16);box-sizing: border-box !important;word-wrap: break-word !important;\"><\/span><span style=\"max-width: 100%;display: inline-block;width: 10px;height: 10px;opacity: 0.6;color: rgb(255, 255, 255);background-color: rgb(172, 29, 16);box-sizing: border-box !important;word-wrap: break-word !important;\"><\/span>&nbsp;&nbsp;&nbsp;<\/span><\/section>\n<section style=\"margin-top: -2px;max-width: 100%;font-size: 0px;box-sizing: border-box !important;word-wrap: break-word !important;\">\n<section style=\"max-width: 100%;display: inline-block;width: 15px;height: 15px;border-width: 1px;border-style: solid;border-color: white;opacity: 0.9;vertical-align: bottom;color: rgb(255, 255, 255);background-color: rgb(172, 29, 16);box-sizing: border-box !important;word-wrap: break-word !important;\"><\/section>\n<section style=\"max-width: 100%;display: inline-block;border-width: 1px;border-style: solid;border-color: rgb(255, 255, 255);width: 30px;height: 30px;line-height: 30px;vertical-align: top;color: rgb(255, 255, 255);background-color: rgb(172, 29, 16);box-sizing: border-box !important;word-wrap: break-word !important;\">\n<p class=\"\" style=\"margin-right: auto;margin-left: auto;max-width: 100%;min-height: 1em;white-space: pre-wrap;min-width: 1px;font-size: 16px;box-sizing: border-box !important;word-wrap: break-word !important;\">03<\/p>\n<\/section>\n<section style=\"max-width: 100%;display: inline-block;width: 15px;height: 15px;border-width: 1px;border-style: solid;border-color: white;opacity: 0.9;vertical-align: top;color: rgb(255, 255, 255);background-color: rgb(172, 29, 16);box-sizing: border-box !important;word-wrap: break-word !important;\"><\/section>\n<\/section>\n<section style=\"margin-top: 3px;margin-left: -33px;max-width: 100%;font-size: 0px;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 16px;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;display: inline-block;width: 10px;height: 10px;opacity: 0.6;color: rgb(255, 255, 255);background-color: rgb(172, 29, 16);box-sizing: border-box !important;word-wrap: break-word !important;\"><\/span><span style=\"margin-bottom: -10px;max-width: 100%;width: 6px;height: 6px;display: inline-block;color: rgb(255, 255, 255);background-color: rgb(172, 29, 16);box-sizing: border-box !important;word-wrap: break-word !important;\"><\/span>&nbsp; &nbsp;<\/span><\/section>\n<\/section>\n<\/section>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);text-align: center;\"><span style=\"max-width: 100%;font-size: 16px;color: rgb(123, 12, 0);box-sizing: border-box !important;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;text-align: justify;box-sizing: border-box !important;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"text-align: justify;\">\u4e0b\u4e00\u6b65\u8ba1\u5212<\/span><\/strong><\/span><\/strong><\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><span style=\"max-width: 100%;font-size: 16px;color: rgb(123, 12, 0);box-sizing: border-box !important;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;text-align: justify;box-sizing: border-box !important;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"text-align: justify;\"><br  \/><\/span><\/strong><\/span><\/strong><\/span><\/p>\n<p style=\"text-align: justify;\">\u201cp53\u5728\u8fd1<strong>70 %<\/strong>\u7684\u7ed3\u80a0\u764c\u548c\u80f0\u817a\u764c\u4e2d\u53d1\u751f\u7a81\u53d8\uff0c\u8fd9\u4e00\u53d1\u73b0\u53ef\u80fd\u5bf9\u7406\u89e3\u8fd9\u4e9b\u75be\u75c5\u4ea7\u751f\u91cd\u5927\u5f71\u54cd\u3002\u56e0\u6b64\uff0c\u63a5\u4e0b\u6765\u6211\u4eec\u5c06\u7ee7\u7eed\u7814\u7a76\u53c2\u4e0eDNA\u4fee\u590d\u7684\u57fa\u56e0\uff0c\u660e\u786e\u5b83\u4eec\u662f\u5426\u540c\u6837\u53ef\u80fd\u5e2e\u52a9p53\u6709\u6548\u9884\u9632\u764c\u75c7\u7684\u53d1\u751f\u548c\u53d1\u5c55\u3002\u201d Janic\u535a\u58eb\u603b\u7ed3\u9053\u3002<\/p>\n<p style=\"text-align: justify;\"><br  \/><\/p>\n<p style=\"text-align: right;\"><strong>\u8d23\u7f16\uff1a\u6d6e\u82cf<\/strong><\/p>\n<section  class=\"\" style=\"white-space: normal;max-width: 100%;color: rgb(51, 51, 51);\">\n<section  style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\">\n<section  class=\"\" style=\"max-width: 100%;line-height: 28.4444px;font-family: \u5fae\u8f6f\u96c5\u9ed1;border-width: 0px;border-style: none;border-color: initial;box-sizing: border-box !important;word-wrap: break-word !important;overflow-wrap: break-word !important;\">\n<section  style=\"margin: 1em auto;max-width: 100%;border-width: 0px;border-style: none;border-color: initial;text-align: center;width: 941px;box-sizing: border-box !important;word-wrap: break-word !important;overflow-wrap: break-word !important;\"><span class=\"\"  style=\"max-width: 100%;width: 941px;border-bottom: 1px solid rgb(172, 29, 16);border-top-color: rgb(172, 29, 16);border-right-color: rgb(172, 29, 16);border-left-color: rgb(172, 29, 16);display: inline-block;box-sizing: border-box !important;word-wrap: break-word !important;overflow-wrap: break-word !important;\"><\/p>\n<section class=\"\" style=\"margin-bottom: -3px;padding-top: 5px;padding-right: 10px;padding-left: 10px;max-width: 100%;display: inline-block;min-height: 32px;border-bottom: 5px solid rgb(172, 29, 16);font-size: 20px;color: rgb(121, 121, 121);box-sizing: border-box !important;word-wrap: break-word !important;overflow-wrap: break-word !important;\">\n<p class=\"\" style=\"margin-top: 5px;margin-bottom: 5px;max-width: 100%;min-height: 1em;line-height: 1.6em;font-size: 16px;box-sizing: border-box !important;word-wrap: break-word !important;overflow-wrap: break-word !important;\">End<\/p>\n<\/section>\n<p><\/span><\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<p class=\"\" style=\"white-space: normal;max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><strong class=\"\" style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"><span class=\"\" style=\"max-width: 100%;font-size: 12px;box-sizing: border-box !important;word-wrap: break-word !important;\">\u53c2\u8003\u8d44\u6599\uff1a<\/span><\/strong><span style=\"max-width: 100%;font-size: 12px;box-sizing: border-box !important;word-wrap: break-word !important;\">1\uff09<span style=\"text-align: justify;\"><\/span><\/span><span style=\"max-width: 100%;font-size: 12px;box-sizing: border-box !important;word-wrap: break-word !important;\">Key cancer-fighting gene&#8217;s secret weapons revealed<\/span><\/p>\n<p class=\"\" style=\"white-space: normal;max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><span style=\"max-width: 100%;font-size: 12px;box-sizing: border-box !important;word-wrap: break-word !important;\"><br  \/><\/span><\/p>\n<section  class=\"\" style=\"font-size: 16px;white-space: normal;max-width: 100%;box-sizing: border-box;letter-spacing: 0.544px;text-align: justify;background-color: rgb(255, 255, 255);color: rgb(62, 62, 62);line-height: 25.6px;font-family: \u5fae\u8f6f\u96c5\u9ed1;border-width: 0px;border-style: none;word-wrap: break-word !important;overflow-wrap: break-word !important;\">\n<section class=\"\"  style=\"padding: 2px;max-width: 100%;box-sizing: border-box;border-width: 1px;border-style: dotted;border-color: rgb(218, 98, 71);word-wrap: break-word !important;overflow-wrap: break-word !important;\">\n<section class=\"\" style=\"margin: 5px auto;max-width: 100%;box-sizing: border-box;border-width: 0px;border-style: none;word-wrap: break-word !important;overflow-wrap: break-word !important;\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;height: 25px;color: inherit;word-wrap: break-word !important;overflow-wrap: break-word !important;\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;height: 25px;width: 50px;float: left;border-top: 2px solid rgb(172, 29, 16);border-right-color: rgb(172, 29, 16);border-bottom-color: rgb(172, 29, 16);border-left: 2px solid rgb(172, 29, 16);color: inherit;word-wrap: break-word !important;overflow-wrap: break-word !important;\"><\/section>\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;display: inline-block;color: rgb(172, 29, 16);clear: both;border-color: rgb(172, 29, 16);word-wrap: break-word !important;overflow-wrap: break-word !important;\"><\/section>\n<\/section>\n<section class=\"\"  style=\"margin: -0.8em 0.3em;padding: 0.8em;max-width: 100%;box-sizing: border-box;color: inherit;word-wrap: break-word !important;overflow-wrap: break-word !important;\">\n<p class=\"\" style=\"max-width: 100%;min-height: 1em;overflow-wrap: break-word;color: rgb(51, 51, 51);font-size: 1em;line-height: 1.75em;word-break: break-all;box-sizing: border-box !important;word-wrap: break-word !important;\"><span class=\"\" style=\"max-width: 100%;color: rgb(0, 0, 0);line-height: 22.4px;font-size: 14px;box-sizing: border-box !important;word-wrap: break-word !important;overflow-wrap: break-word !important;\">\u672c\u6587\u7cfb\u751f\u7269\u63a2\u7d22\u539f\u521b\uff0c\u6b22\u8fce\u4e2a\u4eba\u8f6c\u53d1\u5206\u4eab\u3002\u5176\u4ed6\u4efb\u4f55\u5a92\u4f53\u3001\u7f51\u7ad9\u5982\u9700\u8f6c\u8f7d\uff0c\u987b\u5728\u6b63\u6587\u524d\u6ce8\u660e\u6765\u6e90\u751f\u7269\u63a2\u7d22\u3002<\/span><\/p>\n<\/section>\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;height: 25px;color: inherit;word-wrap: break-word !important;overflow-wrap: break-word !important;\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;height: 25px;width: 50px;float: right;border-bottom: 2px solid rgb(172, 29, 16);border-top-color: rgb(172, 29, 16);border-right: 2px solid rgb(172, 29, 16);border-left-color: rgb(172, 29, 16);color: inherit;word-wrap: break-word !important;overflow-wrap: break-word !important;\"><\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<p class=\"\" style=\"white-space: normal;max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\">\n<blockquote class='keep-source'>\n<p>\u59cb\u53d1\u4e8e\u5fae\u4fe1\u516c\u4f17\u53f7\uff1a                         \u751f\u7269\u63a2\u7d22                      <\/p>\n<\/blockquote>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>p53\u662f\u4e00\u79cd\u80bf\u7624\u6291\u5236\u57fa\u56e0\uff0c\u8be5\u57fa\u56e0\u7684\u5931\u6d3b\u5bb9\u6613\u589e\u52a0\u80bf\u7624\u53d1\u5c55\u7684\u98ce\u9669\u3002\u8fd1\u65e5\uff0c\u6765\u81ea\u6fb3\u5927\u5229\u4e9a\u4e00\u7ec4\u79d1\u5b66\u5bb6\u53d1\u73b0\uff0c\u5728\u4eba\u4f53\u6b63\u5e38DN [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":10239,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[2],"tags":[],"_links":{"self":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/10238"}],"collection":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/comments?post=10238"}],"version-history":[{"count":1,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/10238\/revisions"}],"predecessor-version":[{"id":10242,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/10238\/revisions\/10242"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/media\/10239"}],"wp:attachment":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/media?parent=10238"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/categories?post=10238"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/tags?post=10238"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}