{"id":10321,"date":"2018-06-11T01:00:00","date_gmt":"2018-07-27T09:46:11","guid":{"rendered":"http:\/\/www.05921.net\/index.php\/2018\/07\/27\/%e8%80%97%e6%97%b635%e5%b9%b4%ef%bc%81nejm%e6%9c%80%e6%96%b0%e6%88%90%e6%9e%9c%e7%a0%b4%e8%a7%a3%e7%bd%95%e8%a7%81%e5%ae%b6%e6%97%8f%e8%a1%80%e6%b6%b2%e4%b9%8b%e8%b0%9c\/"},"modified":"2018-07-27T17:46:12","modified_gmt":"2018-07-27T09:46:12","slug":"%e8%80%97%e6%97%b635%e5%b9%b4%ef%bc%81nejm%e6%9c%80%e6%96%b0%e6%88%90%e6%9e%9c%e7%a0%b4%e8%a7%a3%e7%bd%95%e8%a7%81%e5%ae%b6%e6%97%8f%e8%a1%80%e6%b6%b2%e4%b9%8b%e8%b0%9c","status":"publish","type":"post","link":"https:\/\/www.05921.net\/index.php\/10321\/","title":{"rendered":"\u8017\u65f635\u5e74\uff01NEJM\u6700\u65b0\u6210\u679c\u7834\u89e3\u7f55\u89c1\u201c\u5bb6\u65cf\u8840\u6db2\u4e4b\u8c1c\u201d"},"content":{"rendered":"<div class=\"bpp-post-content\">\n<section  class=\"\" style=\"font-size: 16px;white-space: normal;max-width: 100%;letter-spacing: 0.476px;text-align: justify;background-color: rgb(255, 255, 255);color: rgb(62, 62, 62);font-family: \u5fae\u8f6f\u96c5\u9ed1;box-sizing: border-box !important;word-wrap: break-word !important;\">\n<section class=\"bizsvr_0\" style=\"max-width: 100%;border-width: 0px;border-style: none;border-color: initial;box-sizing: border-box !important;word-wrap: break-word !important;\">\n<section class=\"bizsvr_0\" style=\"max-width: 100%;border-width: 0px;border-style: none;border-color: initial;box-sizing: border-box !important;word-wrap: break-word !important;\">\n<section class=\"bizsvr_2\" style=\"padding: 0.8em;max-width: 100%;border-width: 1px 0.4em;border-style: solid;border-color: rgb(172, 29, 16);border-radius: 0.3em;box-sizing: border-box !important;word-wrap: break-word !important;\">\n<p style=\"text-align: justify;\">20\u4e16\u7eaa70\u5e74\u4ee3\u672b\uff0c\u4e00\u540d\u60c5\u51b5\u4e0d\u660e\u7684\u9ad8\u8840\u7ea2\u86cb\u767d\u6c34\u5e73\uff08hemoglobin level\uff0cHb\uff09\u7684\u7537\u5b50\u88ab\u9001\u5230\u4e86\u632a\u5a01Namsos\u533b\u9662\uff0c\u968f\u540e\u8be5\u7537\u5b50\u7684\u56db\u4f4d\u5bb6\u5ead\u6210\u5458\u4e5f\u88ab\u8bca\u65ad\u51fa\u60a3\u6709\u6b64\u75c5\u3002\u4f5c\u4e3a\u8fd9\u4e2a\u5bb6\u5ead\u7684\u6cbb\u7597\u533b\u751f\uff0cKjell Kanel\u00f8nning\u5f7b\u5e95\u68c0\u67e5\u4e86\u60a3\u8005\u53ca\u5176\u5bb6\u4eba\uff0c\u4f46\u59cb\u7ec8\u672a\u53d1\u73b0\u75c5\u56e0\u3002\u76f4\u523035\u5e74\u540eCRISPR\u6280\u672f\u7684\u51fa\u73b0\uff0c\u8fd9\u79cd\u5bb6\u65cf\u6027\u8840\u6db2\u75be\u75c5\u7684\u75c5\u56e0\u624d\u6700\u7ec8\u88ab\u7834\u89e3\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<p><br  \/><\/p>\n<p><img class=\"\"       style=\"\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/07\/beepress8-1532684772.jpeg\" alt=\"\u8017\u65f635\u5e74\uff01NEJM\u6700\u65b0\u6210\u679c\u7834\u89e3\u7f55\u89c1\u201c\u5bb6\u65cf\u8840\u6db2\u4e4b\u8c1c\u201d\" title=\"\u8017\u65f635\u5e74\uff01NEJM\u6700\u65b0\u6210\u679c\u7834\u89e3\u7f55\u89c1\u201c\u5bb6\u65cf\u8840\u6db2\u4e4b\u8c1c\u201d\"><\/p>\n<p style=\"text-align: center;line-height: 1.75em;\"><span style=\"color: rgb(136, 136, 136);\">Dr. Anders Waage (left) and Dr. Anders Sundan, both with the Norwegian University of Science and Technology, played a critical role in understanding how a Norwegian family could have such high hemoglobin levels. Credit: NTNU<\/span><\/p>\n<p style=\"text-align: justify;line-height: 1.75em;\"><br  \/><\/p>\n<p style=\"text-align: justify;line-height: 1.75em;\">\u201c\u6b63\u5e38\u7684Hb\u503c\u572812.5\u523017\u4e4b\u95f4\uff08\u5373\u6bcf100\u6beb\u5347\u8840\u6db2\u4e2d\u8840\u7ea2\u86cb\u767d\u7684\u514b\u6570\uff09\uff0c\u800c\u60a3\u6709\u8fd9\u79cd\u75be\u75c5\u7684\u4ebaHb\u503c\u572820\u5de6\u53f3\u3002\u8fd9\u4e00\u6570\u503c\u8fdc\u8fdc\u8d85\u8fc7\u4e86\u5174\u594b\u5242\u7684\u9650\u5236\uff08\u670d\u7528\u5174\u594b\u5242\u7684\u4e3b\u8981\u5224\u65ad\u6307\u6807\u4e3a\u8840\u6db2\u4e2d\u8840\u7ea2\u86cb\u767d\u542b\u91cf\u7684\u5347\u9ad8\uff09\u3002\u201d\u632a\u5a01\u79d1\u6280\u5927\u5b66\u4e34\u5e8a\u4e0e\u5206\u5b50\u533b\u5b66\u7cfb\u6559\u6388Anders Waage\u4ecb\u7ecd\u5230\u3002<\/p>\n<p><br  \/><\/p>\n<p style=\"text-align: justify;line-height: 1.75em;\">Waage\u4e5f\u662f\u4e00\u540d\u533b\u751f\uff0c<strong>&nbsp;90\u5e74\u4ee3\u521d\uff0c<\/strong>\u5f53\u4ed6\u5728St. Olavs\u533b\u9662\u89c1\u5230\u8fd9\u4e2a\u6765\u81eaTr\u00f8ndelag\u53bf\u7684\u5bb6\u5ead\u65f6\uff0c\u4fbf\u51b3\u5b9a\u4ecb\u5165\u5230\u8fd9\u4e2a\u6545\u4e8b\u4e2d\u3002\u901a\u8fc7\u68c0\u6d4b\uff0cWaage\u53d1\u73b0\uff0c\u60a3\u8005\u5bb6\u5ead\u6210\u5458\u65e2\u672a\u5438\u6bd2\u4e5f\u672a\u751f\u75c5\uff0c\u4e14\u6709\u4e00\u534a\u7684\u5bb6\u5ead\u6210\u5458\u51fa\u751f\u65f6\u5c31\u6709\u8fd9\u79cd\u60c5\u51b5\u3002<\/p>\n<p><br  \/><\/p>\n<p style=\"text-align: justify;line-height: 1.75em;\">\u4e4b\u540e\uff0c\u66f4\u591a\u7684\u7814\u7a76\u4eba\u5458\u5f00\u59cb\u5bf9\u8fd9\u4e2a\u75c5\u4f8b\u611f\u5174\u8da3\uff0c\u5176\u4e2d\u5305\u62ec\u5965\u65af\u9646\u5927\u5b66\u533b\u9662\u7684Bernt Ly\u3002<strong>1983\u5e74\uff0c<\/strong>\u4ed6\u548ckanelloning\u7b49\u4eba\u5199\u4e86\u4e00\u7bc7\u5173\u4e8e\u8fd9\u4e00\u73b0\u8c61\u7684\u79d1\u5b66\u6587\u7ae0\u3002Waage\u56de\u5fc6\u9053\uff1a\u201c\u73b0\u5728\u770b\u6765\uff0c\u4ed6\u4eec\u5f53\u65f6\u8ddf\u8e2a\u7684\u6240\u6709\u7ebf\u7d22\u90fd\u662f\u6b7b\u8def\u4e00\u6761\uff0c\u6839\u672c\u65e0\u6cd5\u68c0\u67e5\u51fa\u4efb\u4f55\u4e1c\u897f\u3002\u201d<\/p>\n<p><br  \/><\/p>\n<p style=\"text-align: justify;line-height: 1.75em;\">\u968f\u7740\u65f6\u95f4\u4e00\u70b9\u70b9\u7684\u6d41\u901d\uff0cWaage\u63a5\u8fde\u4e0b\u4ee4\u8fdb\u884c\u65b0\u7684\u6d4b\u8bd5\u548c\u8c03\u67e5\uff0c\u4f46\u90fd\u6ca1\u6709\u627e\u5230\u7ebf\u7d22\u3002\u7814\u7a76\u4eba\u5458\u5f00\u59cb\u4e0d\u65ad\u8d28\u95ee\u81ea\u5df1\u63a5\u4e0b\u6765\u5c06\u4f1a\u53d1\u751f\u4ec0\u4e48\u3002<\/p>\n<p><br  \/><\/p>\n<p style=\"text-align: justify;line-height: 1.75em;\">\u6070\u9022\u5f53\u65f6\uff0c\u4e00\u540d\u82ac\u5170\u6ed1\u96ea\u8005\u51fa\u73b0\u5728\u533b\u5b66\u6587\u732e\u4e2d\uff0c\u4ed6\u5728\u4e16\u9526\u8d5b\u548c\u5965\u8fd0\u4f1a\u4e0a\u90fd\u83b7\u5f97\u4e86\u51e0\u5757\u91d1\u724c\u3002\u6d4b\u8bd5\u663e\u793a\u4ed6\u7684\u8840\u7ea2\u86cb\u767d\u6c34\u5e73\u4e3a22\uff0c\u5f53\u65f6\u8fd9\u4e00\u73b0\u8c61\u53ea\u80fd\u7528\u5174\u594b\u5242\u6765\u89e3\u91ca\u3002\u4f46\u662f\uff0c\u5f53\u82ac\u5170\u533b\u751f\u5bf9\u6ed1\u96ea\u8005\u7684\u5176\u4ed6\u5bb6\u5ead\u6210\u5458\u8fdb\u884c\u68c0\u67e5\u65f6\uff0c\u4ed6\u4eec\u53d1\u73b0\u5176\u4e2d30\u591a\u4eba\u7684Hb\u6c34\u5e73\u5747\u8d85\u8fc720\u3002<\/p>\n<p><br  \/><\/p>\n<p style=\"text-align: justify;line-height: 1.75em;\">\u5230<strong>90\u5e74\u4ee3\u672b<\/strong>\uff0c\u533b\u5b66\u65b9\u6cd5\u6709\u6240\u6539\u8fdb\u540e\uff0c\u7814\u7a76\u4eba\u5458\u53d1\u73b0\uff0c\u82ac\u5170\u5bb6\u5ead\u4e2d\u7684\u4fc3\u7ea2\u7ec6\u80de\u751f\u6210\u7d20\uff08EPO\uff09 \u6fc0\u7d20\u53d7\u4f53\u6709\u4e00\u79cd\u5148\u5929\u7a81\u53d8\uff0c\u5bfc\u81f4\u8be5\u53d7\u4f53\u4e00\u76f4\u5904\u4e8e\u5174\u594b\u72b6\u6001\uff08\u5c3d\u7ba1EPO\u5e76\u4e0d\u4e0e\u53d7\u4f53\u7ed3\u5408\uff09\u3002\u8fd9\u5bfc\u81f4\u7ea2\u7ec6\u80de\u8fc7\u5ea6\u4ea7\u751f\uff0c\u8840\u6db2\u4e2dHb\u542b\u91cf\u589e\u52a0\u3002\u81f3\u6b64\uff0c\u79d1\u5b66\u5bb6\u4eec\u8bc1\u5b9e\u8fd9\u79cd\u60c5\u51b5\u662f\u5148\u5929\u6027\u7684\uff0c\u5e76\u5c06\u5176\u79f0\u4e3a\u5bb6\u65cf\u6027\u7ea2\u7ec6\u80de\u589e\u591a\u75c7\u3002\u5c3d\u7ba1\u5177\u6709\u540c\u6837\u7684\u9ad8Hb\u7ed3\u679c\uff0c\u4f46\u663e\u7136\uff0c\u8fd9\u4e0d\u662f\u7531\u6ce8\u5165\u8840\u6db2\u5174\u594b\u5242\u800c\u5bfc\u81f4\u7684\u3002<\/p>\n<p><br  \/><\/p>\n<p style=\"text-align: justify;line-height: 1.75em;\">\u5bf9Waage\u6765\u8bf4\uff0c\u82ac\u5170\u5bb6\u5ead\u7684\u7814\u7a76\u610f\u5473\u7740\uff0c\u632a\u5a01Tr\u00f8ndelag\u7684\u5bb6\u5ead\u53ef\u80fd\u6700\u7ec8\u627e\u5230\u4e86\u8c1c\u5e95\u3002\u201c\u6211\u4eec\u53ef\u4ee5\u7528\u4e0e\u82ac\u5170\u4eba\u4e00\u6837\u7684\u65b9\u6cd5\uff0c<strong>1998\u5e74<\/strong>\uff0c\u4e00\u7bc7\u7855\u58eb\u8bba\u6587\u5199\u4e86\u8fd9\u4e2a\u6848\u4f8b\u3002\u8fd9\u540d\u5b66\u751f\u89c2\u5bdf\u4e86\u632a\u5a01\u5bb6\u5ead\u4e2d\u7684EPO\u53d7\u4f53\uff0c\u4ee5\u786e\u5b9a\u5176\u7a81\u53d8\u662f\u5426\u4e0e\u82ac\u5170\u5bb6\u5ead\u76f8\u4f3c\u3002\u201d\u4ed6\u8bf4\u3002<\/p>\n<p><br  \/><\/p>\n<p style=\"text-align: justify;line-height: 1.75em;\">\u201c\u4f46\u7b54\u6848\u662f\u5426\u5b9a\u7684\u3002\u5b66\u751f\u4ec0\u4e48\u4e5f\u6ca1\u53d1\u73b0\uff0c\u6211\u4eec\u53c8\u56de\u5230\u4e86\u539f\u5730\u3002\u201d\u8fd9\u9879\u7814\u7a76\u7684\u5171\u540c\u8d1f\u8d23\u4ebaAnders Sundan\u8bf4\u3002<\/p>\n<p><br  \/><\/p>\n<p style=\"text-align: justify;line-height: 1.75em;\">Waage\u548cSundan\u627f\u8ba4\uff0c\u5f53\u65f6\u4ed6\u4eec\u611f\u5230\u6709\u70b9\u6cc4\u6c14\u4e86\u3002\u7531\u4e8e\u8fd9\u5bf9\u5bb6\u5ead\u6765\u8bf4\u5e76\u672a\u4ea7\u751f\u5f88\u5927\u7684\u5f71\u54cd\uff0c\u56e0\u6b64\u6ca1\u6709\u4eba\u518d\u53bb\u52aa\u529b\u63a8\u52a8\u8fd9\u9879\u7814\u7a76\u3002\u52a0\u4e4b\u5f53\u65f6\u4e5f\u6ca1\u6709\u65b0\u7684\u65b9\u6cd5\uff0c\u7814\u7a76\u4eba\u5458\u9664\u4e86\u7b49\u5f85\u597d\u50cf\u4e5f\u5e76\u6ca1\u6709\u5176\u4ed6\u89e3\u51b3\u65b9\u6cd5\u4e86\u3002<\/p>\n<section class=\"\"  style=\"white-space: normal;max-width: 100%;color: rgb(51, 51, 51);\">\n<section style=\"margin: 10px auto;max-width: 100%;text-align: center;box-sizing: border-box !important;word-wrap: break-word !important;\">\n<section style=\"margin-bottom: 3px;margin-left: 33px;max-width: 100%;font-size: 0px;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 16px;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"margin-bottom: 10px;max-width: 100%;width: 6px;height: 6px;display: inline-block;color: rgb(255, 255, 255);background-color: rgb(172, 29, 16);\"><\/span><span style=\"max-width: 100%;display: inline-block;width: 10px;height: 10px;opacity: 0.6;color: rgb(255, 255, 255);background-color: rgb(172, 29, 16);\"><\/span>&nbsp;&nbsp;&nbsp;<\/span><\/section>\n<section style=\"margin-top: -2px;max-width: 100%;font-size: 0px;box-sizing: border-box !important;word-wrap: break-word !important;\">\n<section style=\"display: inline-block;max-width: 100%;width: 15px;height: 15px;border-width: 1px;border-style: solid;border-color: white;opacity: 0.9;vertical-align: bottom;color: rgb(255, 255, 255);background-color: rgb(172, 29, 16);box-sizing: border-box !important;word-wrap: break-word !important;\"><\/section>\n<section style=\"display: inline-block;max-width: 100%;border-width: 1px;border-style: solid;border-color: rgb(255, 255, 255);width: 30px;height: 30px;line-height: 30px;vertical-align: top;color: rgb(255, 255, 255);background-color: rgb(172, 29, 16);box-sizing: border-box !important;word-wrap: break-word !important;\">\n<p class=\"\" style=\"margin-right: auto;margin-left: auto;max-width: 100%;min-height: 1em;white-space: pre-wrap;min-width: 1px;font-size: 16px;box-sizing: border-box !important;word-wrap: break-word !important;\">01<\/p>\n<\/section>\n<section style=\"display: inline-block;max-width: 100%;width: 15px;height: 15px;border-width: 1px;border-style: solid;border-color: white;opacity: 0.9;vertical-align: top;color: rgb(255, 255, 255);background-color: rgb(172, 29, 16);box-sizing: border-box !important;word-wrap: break-word !important;\"><\/section>\n<\/section>\n<section style=\"margin-top: 3px;margin-left: -33px;max-width: 100%;font-size: 0px;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 16px;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;display: inline-block;width: 10px;height: 10px;opacity: 0.6;color: rgb(255, 255, 255);background-color: rgb(172, 29, 16);\"><\/span><span style=\"margin-bottom: -10px;max-width: 100%;width: 6px;height: 6px;display: inline-block;color: rgb(255, 255, 255);background-color: rgb(172, 29, 16);\"><\/span>&nbsp; &nbsp;<\/span><\/section>\n<\/section>\n<\/section>\n<p style=\"white-space: normal;max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);text-align: center;\"><span style=\"max-width: 100%;font-size: 16px;color: rgb(123, 12, 0);box-sizing: border-box !important;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;text-align: justify;box-sizing: border-box !important;word-wrap: break-word !important;\">\u4e00\u70b9\u53d1\u73b0<\/span><\/strong><\/span><\/p>\n<p style=\"text-align: justify;line-height: 1.75em;\"><br  \/><\/p>\n<p style=\"text-align: justify;line-height: 1.75em;\">\u65f6\u95f4\u63a8\u81f3<strong>2004\u5e74<\/strong>\uff0cWaage\u53c2\u52a0\u4e86\u6b27\u6d32\u8840\u6db2\u5b66\u534f\u4f1a\uff08European Hematology Association\uff09\u5e74\u4f1a\u3002\u5728\u90a3\u91cc\uff0c\u4ed6\u542c\u53d6\u4e86\u5df4\u585e\u5c14\u5927\u5b66\u7684Radek C. Skoda\u6559\u6388\u7684\u53d1\u8a00\u3002\u968f\u540e\uff0cWaage\u4e0eSkoda\u53d6\u5f97\u8054\u7cfb\uff0c\u8ba8\u8bba\u4e86Tr\u00f8ndelag\u7684\u5bb6\u5ead\u95ee\u9898\u3002Skoda\u5bf9\u8fd9\u4e00\u73b0\u8c61\u5f88\u611f\u5174\u8da3\uff0c\u4ed6\u4eec\u8fdb\u884c\u4e86\u63a5\u89e6\u3002\u5728\u63a5\u4e0b\u6765\u7684\u51e0\u5e74\u91cc\uff0c\u4ed6\u4eec\u6536\u96c6\u4e86\u66f4\u591a\u7684\u4fe1\u606f\uff0c\u5e76\u4ea4\u6362\u4e86\u65b0\u7684\u6570\u636e\u548c\u89c2\u70b9\u3002<\/p>\n<p><br  \/><\/p>\n<p style=\"text-align: justify;line-height: 1.75em;\">\u968f\u7740\u65b0\u5343\u5e74\u7684\u7b2c\u4e00\u4e2a\u5341\u5e74\u91cc\u65b9\u6cd5\u3001\u6d4b\u8bd5\u548c\u5206\u6790\u5de5\u5177\u7684\u4e0d\u65ad\u6539\u8fdb\uff0c<strong>2008\u5e74<\/strong>\uff0c\u8fd9\u9879\u7814\u7a76\u7ec8\u4e8e\u6709\u4e86\u7a81\u7834\u3002\u7814\u7a76\u4eba\u5458\u53d1\u73b0\uff1a\u5728\u6240\u6709\u53d7\u8840\u7ea2\u86cb\u767d\u6c34\u5e73\u589e\u52a0\u5f71\u54cd\u7684\u5bb6\u5ead\u6210\u5458\u4e2d\uff0c\u57fa\u56e0\u7ec4\u7684\u6709\u9650\u533a\u57df\u662f\u76f8\u540c\u7684\u3002\u8fd9\u4e2a\u533a\u57df\u5305\u542b215\u4e2a\u88ab\u6d4b\u5e8f\u7684\u57fa\u56e0\u3002\u8ba9\u6240\u6709\u4eba\u60ca\u8bb6\u7684\u662f\uff0c\u4ed6\u4eec\u53d1\u73b0\u4e86<strong>EPO\u57fa\u56e0\u7684\u7a81\u53d8\u3002<\/strong>Hb\u503c\u9ad8\u7684\u5bb6\u5ead\u6210\u5458\u90fd\u6709\u7a81\u53d8\uff0c\u800cHb\u503c\u6b63\u5e38\u7684\u5bb6\u5ead\u6210\u5458\u6ca1\u6709\u7a81\u53d8\u3002\u8fd9\u9879\u53d1\u73b0\u6307\u51fa\u4e86EPO\u672c\u8eab\u7684\u4e00\u4e2a\u9519\u8bef\u3002<\/p>\n<section class=\"\"  style=\"white-space: normal;max-width: 100%;color: rgb(51, 51, 51);\">\n<section style=\"margin: 10px auto;max-width: 100%;text-align: center;box-sizing: border-box !important;word-wrap: break-word !important;\">\n<section style=\"margin-bottom: 3px;margin-left: 33px;max-width: 100%;font-size: 0px;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 16px;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"margin-bottom: 10px;max-width: 100%;width: 6px;height: 6px;display: inline-block;color: rgb(255, 255, 255);background-color: rgb(172, 29, 16);\"><\/span><span style=\"max-width: 100%;display: inline-block;width: 10px;height: 10px;opacity: 0.6;color: rgb(255, 255, 255);background-color: rgb(172, 29, 16);\"><\/span>&nbsp;&nbsp;&nbsp;<\/span><\/section>\n<section style=\"margin-top: -2px;max-width: 100%;font-size: 0px;box-sizing: border-box !important;word-wrap: break-word !important;\">\n<section style=\"display: inline-block;max-width: 100%;width: 15px;height: 15px;border-width: 1px;border-style: solid;border-color: white;opacity: 0.9;vertical-align: bottom;color: rgb(255, 255, 255);background-color: rgb(172, 29, 16);box-sizing: border-box !important;word-wrap: break-word !important;\"><\/section>\n<section style=\"display: inline-block;max-width: 100%;border-width: 1px;border-style: solid;border-color: rgb(255, 255, 255);width: 30px;height: 30px;line-height: 30px;vertical-align: top;color: rgb(255, 255, 255);background-color: rgb(172, 29, 16);box-sizing: border-box !important;word-wrap: break-word !important;\">\n<p class=\"\" style=\"margin-right: auto;margin-left: auto;max-width: 100%;min-height: 1em;white-space: pre-wrap;min-width: 1px;font-size: 16px;box-sizing: border-box !important;word-wrap: break-word !important;\">02<\/p>\n<\/section>\n<section style=\"display: inline-block;max-width: 100%;width: 15px;height: 15px;border-width: 1px;border-style: solid;border-color: white;opacity: 0.9;vertical-align: top;color: rgb(255, 255, 255);background-color: rgb(172, 29, 16);box-sizing: border-box !important;word-wrap: break-word !important;\"><\/section>\n<\/section>\n<section style=\"margin-top: 3px;margin-left: -33px;max-width: 100%;font-size: 0px;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 16px;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;display: inline-block;width: 10px;height: 10px;opacity: 0.6;color: rgb(255, 255, 255);background-color: rgb(172, 29, 16);\"><\/span><span style=\"margin-bottom: -10px;max-width: 100%;width: 6px;height: 6px;display: inline-block;color: rgb(255, 255, 255);background-color: rgb(172, 29, 16);\"><\/span>&nbsp; &nbsp;<\/span><\/section>\n<\/section>\n<\/section>\n<p style=\"white-space: normal;max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);text-align: center;\"><span style=\"max-width: 100%;font-size: 16px;color: rgb(123, 12, 0);box-sizing: border-box !important;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;text-align: justify;box-sizing: border-box !important;word-wrap: break-word !important;\">\u60f3\u8981\u66f4\u591a<\/span><\/strong><\/span><\/p>\n<p style=\"text-align: justify;line-height: 1.75em;\"><br  \/><\/p>\n<p style=\"text-align: justify;line-height: 1.75em;\">\u5728\u8fd9\u4e00\u53d1\u73b0\u4e4b\u540e\uff0c\u8be5\u9879\u76ee\u53c8\u4e2d\u65ad\u4e86\u4e00\u6bb5\u65f6\u95f4\u3002\u201c\u6211\u4eec\u672c\u53ef\u4ee5\u6ee1\u8db3\u4e8e\u627e\u5230\u5bfc\u81f4\u8fd9\u79cd\u60c5\u51b5\u7684\u7a81\u53d8\uff0c\u5373EPO\u57fa\u56e0\u7684\u7a81\u53d8\u662f\u5bb6\u65cf\u6027\u7ea2\u7ec6\u80de\u589e\u591a\u75c7\u7684\u539f\u56e0\u3002\u8fd9\u6837\u7684\u65b0\u53d1\u73b0\u672c\u8eab\u5c31\u5f88\u6709\u8da3\u4e86\uff0c\u4f46\u4ecd\u6709\u4e00\u4e2a\u60ac\u800c\u672a\u51b3\u7684\u95ee\u9898\u5728\u56f0\u6270\u6211\u4eec\u3002\u201d\u7814\u7a76\u4eba\u5458\u6307\u51fa\u3002<\/p>\n<p><br  \/><\/p>\n<p style=\"text-align: justify;line-height: 1.75em;\">\u4ed6\u4eec\u9884\u8ba1\uff0c\u8fd9\u79cd\u7a81\u53d8\u53ef\u80fd\u4f1a\u5bfc\u81f4\u529f\u80fd\u53d7\u635f\u3002\u90a3\u4e48\u8fd9\u4e00\u5207\u662f\u600e\u4e48\u8054\u7cfb\u5728\u4e00\u8d77\u7684\u5462\uff1f\u8fd9\u4e5f\u662f\u4ed6\u4eec\u8981\u7ee7\u7eed\u89e3\u91ca\u7684\u3002\u4e00\u4e2a\u53ef\u80fd\u7684\u7b54\u6848\u6216\u8bb8\u6b63\u5728\u6162\u6162\u6210\u719f\uff0c\u4f46\u7531\u4e8e\u7f3a\u4e4f\u65b9\u6cd5\uff0c\u56de\u7b54\u8fd9\u4e00\u95ee\u9898\u4ecd\u5e76\u4e0d\u5bb9\u6613\u3002<\/p>\n<section class=\"\"  style=\"white-space: normal;max-width: 100%;color: rgb(51, 51, 51);\">\n<section style=\"margin: 10px auto;max-width: 100%;text-align: center;box-sizing: border-box !important;word-wrap: break-word !important;\">\n<section style=\"margin-bottom: 3px;margin-left: 33px;max-width: 100%;font-size: 0px;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 16px;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"margin-bottom: 10px;max-width: 100%;width: 6px;height: 6px;display: inline-block;color: rgb(255, 255, 255);background-color: rgb(172, 29, 16);\"><\/span><span style=\"max-width: 100%;display: inline-block;width: 10px;height: 10px;opacity: 0.6;color: rgb(255, 255, 255);background-color: rgb(172, 29, 16);\"><\/span>&nbsp;&nbsp;&nbsp;<\/span><\/section>\n<section style=\"margin-top: -2px;max-width: 100%;font-size: 0px;box-sizing: border-box !important;word-wrap: break-word !important;\">\n<section style=\"display: inline-block;max-width: 100%;width: 15px;height: 15px;border-width: 1px;border-style: solid;border-color: white;opacity: 0.9;vertical-align: bottom;color: rgb(255, 255, 255);background-color: rgb(172, 29, 16);box-sizing: border-box !important;word-wrap: break-word !important;\"><\/section>\n<section style=\"display: inline-block;max-width: 100%;border-width: 1px;border-style: solid;border-color: rgb(255, 255, 255);width: 30px;height: 30px;line-height: 30px;vertical-align: top;color: rgb(255, 255, 255);background-color: rgb(172, 29, 16);box-sizing: border-box !important;word-wrap: break-word !important;\">\n<p class=\"\" style=\"margin-right: auto;margin-left: auto;max-width: 100%;min-height: 1em;white-space: pre-wrap;min-width: 1px;font-size: 16px;box-sizing: border-box !important;word-wrap: break-word !important;\">03<\/p>\n<\/section>\n<section style=\"display: inline-block;max-width: 100%;width: 15px;height: 15px;border-width: 1px;border-style: solid;border-color: white;opacity: 0.9;vertical-align: top;color: rgb(255, 255, 255);background-color: rgb(172, 29, 16);box-sizing: border-box !important;word-wrap: break-word !important;\"><\/section>\n<\/section>\n<section style=\"margin-top: 3px;margin-left: -33px;max-width: 100%;font-size: 0px;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 16px;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;display: inline-block;width: 10px;height: 10px;opacity: 0.6;color: rgb(255, 255, 255);background-color: rgb(172, 29, 16);\"><\/span><span style=\"margin-bottom: -10px;max-width: 100%;width: 6px;height: 6px;display: inline-block;color: rgb(255, 255, 255);background-color: rgb(172, 29, 16);\"><\/span>&nbsp; &nbsp;<\/span><\/section>\n<\/section>\n<\/section>\n<p style=\"white-space: normal;max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);text-align: center;\"><span style=\"max-width: 100%;font-size: 16px;color: rgb(123, 12, 0);box-sizing: border-box !important;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;text-align: justify;box-sizing: border-box !important;word-wrap: break-word !important;\">\u798f\u97f3\u6765\u4e34<\/span><\/strong><\/span><\/p>\n<p style=\"text-align: justify;line-height: 1.75em;\"><br  \/><\/p>\n<p style=\"text-align: justify;line-height: 1.75em;\"><strong>2016\u5e74\uff0c<\/strong>Waage\u6536\u5230\u4e86Skoda\u535a\u58eb\u7684\u7535\u5b50\u90ae\u4ef6\uff0c\u4fe1\u4e2d\u8bf4\u4ed6\u505a\u4e86\u5927\u91cf\u5206\u5b50\u5de5\u4f5c\u4e14\u53d6\u5f97\u4e86\u5f88\u597d\u7684\u6210\u679c\u3002\u968f\u7740<strong>CRISPR<\/strong>\u57fa\u56e0\u7f16\u8f91\u6280\u672f\u7684\u51fa\u73b0\uff0c\u7814\u7a76\u4eba\u5458\u53ef\u4ee5\u81ea\u7531\u526a\u5207\u548c\u7c98\u8d34DNA\u7247\u6bb5\u5e76\u521b\u5efa\u65b0\u7684\u57fa\u56e0\u5e8f\u5217\u4e86\u3002<\/p>\n<p><br  \/><\/p>\n<p style=\"text-align: justify;line-height: 1.75em;\">\u7814\u7a76\u5c0f\u7ec4\u505a\u7684\u7b2c\u4e00\u4ef6\u4e8b\u5c31\u662f\u5c06\u7a81\u53d8\u63d2\u5165\u4e00\u4e2a\u4ea7\u751fEPO\u7684\u7ec6\u80de\u4e2d\u2014\u2014\u679c\u7136\uff0c\u5f53\u7a81\u53d8\u63d2\u5165\u65f6\uff0c\u7ec6\u80de\u4ea7\u751f\u7684EPO\u662f\u539f\u6765\u7684<strong>10\u500d<\/strong>\uff0c\u5f53EPO\u542b\u91cf\u589e\u52a0\u65f6\uff0c\u7ea2\u7ec6\u80de\u751f\u6210\u589e\u52a0\uff0c\u8840\u7ea2\u86cb\u767d\u503c\u5347\u9ad8\u3002\u6700\u7ec8\uff0c\u4ed6\u4eec\u627e\u5230\u4e86\u6b63\u786e\u7684\u7a81\u53d8\u3002<\/p>\n<section class=\"\"  style=\"white-space: normal;max-width: 100%;color: rgb(51, 51, 51);\">\n<section style=\"margin: 10px auto;max-width: 100%;text-align: center;box-sizing: border-box !important;word-wrap: break-word !important;\">\n<section style=\"margin-bottom: 3px;margin-left: 33px;max-width: 100%;font-size: 0px;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 16px;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"margin-bottom: 10px;max-width: 100%;width: 6px;height: 6px;display: inline-block;color: rgb(255, 255, 255);background-color: rgb(172, 29, 16);\"><\/span><span style=\"max-width: 100%;display: inline-block;width: 10px;height: 10px;opacity: 0.6;color: rgb(255, 255, 255);background-color: rgb(172, 29, 16);\"><\/span>&nbsp;&nbsp;&nbsp;<\/span><\/section>\n<section style=\"margin-top: -2px;max-width: 100%;font-size: 0px;box-sizing: border-box !important;word-wrap: break-word !important;\">\n<section style=\"display: inline-block;max-width: 100%;width: 15px;height: 15px;border-width: 1px;border-style: solid;border-color: white;opacity: 0.9;vertical-align: bottom;color: rgb(255, 255, 255);background-color: rgb(172, 29, 16);box-sizing: border-box !important;word-wrap: break-word !important;\"><\/section>\n<section style=\"display: inline-block;max-width: 100%;border-width: 1px;border-style: solid;border-color: rgb(255, 255, 255);width: 30px;height: 30px;line-height: 30px;vertical-align: top;color: rgb(255, 255, 255);background-color: rgb(172, 29, 16);box-sizing: border-box !important;word-wrap: break-word !important;\">\n<p class=\"\" style=\"margin-right: auto;margin-left: auto;max-width: 100%;min-height: 1em;white-space: pre-wrap;min-width: 1px;font-size: 16px;box-sizing: border-box !important;word-wrap: break-word !important;\">04<\/p>\n<\/section>\n<section style=\"display: inline-block;max-width: 100%;width: 15px;height: 15px;border-width: 1px;border-style: solid;border-color: white;opacity: 0.9;vertical-align: top;color: rgb(255, 255, 255);background-color: rgb(172, 29, 16);box-sizing: border-box !important;word-wrap: break-word !important;\"><\/section>\n<\/section>\n<section style=\"margin-top: 3px;margin-left: -33px;max-width: 100%;font-size: 0px;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 16px;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;display: inline-block;width: 10px;height: 10px;opacity: 0.6;color: rgb(255, 255, 255);background-color: rgb(172, 29, 16);\"><\/span><span style=\"margin-bottom: -10px;max-width: 100%;width: 6px;height: 6px;display: inline-block;color: rgb(255, 255, 255);background-color: rgb(172, 29, 16);\"><\/span>&nbsp; &nbsp;<\/span><\/section>\n<\/section>\n<\/section>\n<p style=\"white-space: normal;max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);text-align: center;\"><span style=\"max-width: 100%;font-size: 16px;color: rgb(123, 12, 0);box-sizing: border-box !important;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;text-align: justify;box-sizing: border-box !important;word-wrap: break-word !important;\">\u597d\u5947\u5fc3\u9a71\u4f7f<\/span><\/strong><\/span><\/p>\n<p style=\"text-align: justify;line-height: 1.75em;\"><br  \/><\/p>\n<p style=\"text-align: justify;line-height: 1.75em;\">Waage\u8bf4\uff1a\u201c35\u5e74\u6765\uff0c\u8fd9\u9879\u7814\u7a76\u4e00\u76f4\u53d7\u5230\u597d\u5947\u5fc3\u7684\u9a71\u4f7f\u3002\u56db\u4ee3\u53d7\u5f71\u54cd\u7684\u5bb6\u5ead\u6210\u5458\u589e\u52a0\u4e86Hb\u5347\u9ad8\u6216\u6b63\u5e38\u7684\u4eba\u7684\u6570\u91cf\uff0c\u4f7f\u627e\u5230\u4e0e\u7a81\u53d8\u4e4b\u95f4\u7684\u8054\u7cfb\u66f4\u5bb9\u6613\u3002\u4f46\u6700\u91cd\u8981\u7684\u662f\uff0c\u8fd9\u4e00\u65f6\u671f\u6280\u672f\u7684\u5de8\u5927\u8fdb\u6b65\u4f7f\u6211\u4eec\u6709\u53ef\u80fd\u8bc1\u660e\u7a81\u53d8\u786e\u5b9e\u5bfc\u81f4\u4e86Hb\u6c34\u5e73\u7684\u5347\u9ad8\u3002\u201d<\/p>\n<section class=\"\"  style=\"white-space: normal;max-width: 100%;color: rgb(51, 51, 51);\">\n<section style=\"margin: 10px auto;max-width: 100%;text-align: center;box-sizing: border-box !important;word-wrap: break-word !important;\">\n<section style=\"margin-bottom: 3px;margin-left: 33px;max-width: 100%;font-size: 0px;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 16px;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"margin-bottom: 10px;max-width: 100%;width: 6px;height: 6px;display: inline-block;color: rgb(255, 255, 255);background-color: rgb(172, 29, 16);\"><\/span><span style=\"max-width: 100%;display: inline-block;width: 10px;height: 10px;opacity: 0.6;color: rgb(255, 255, 255);background-color: rgb(172, 29, 16);\"><\/span>&nbsp;&nbsp;&nbsp;<\/span><\/section>\n<section style=\"margin-top: -2px;max-width: 100%;font-size: 0px;box-sizing: border-box !important;word-wrap: break-word !important;\">\n<section style=\"display: inline-block;max-width: 100%;width: 15px;height: 15px;border-width: 1px;border-style: solid;border-color: white;opacity: 0.9;vertical-align: bottom;color: rgb(255, 255, 255);background-color: rgb(172, 29, 16);box-sizing: border-box !important;word-wrap: break-word !important;\"><\/section>\n<section style=\"display: inline-block;max-width: 100%;border-width: 1px;border-style: solid;border-color: rgb(255, 255, 255);width: 30px;height: 30px;line-height: 30px;vertical-align: top;color: rgb(255, 255, 255);background-color: rgb(172, 29, 16);box-sizing: border-box !important;word-wrap: break-word !important;\">\n<p class=\"\" style=\"margin-right: auto;margin-left: auto;max-width: 100%;min-height: 1em;white-space: pre-wrap;min-width: 1px;font-size: 16px;box-sizing: border-box !important;word-wrap: break-word !important;\">05<\/p>\n<\/section>\n<section style=\"display: inline-block;max-width: 100%;width: 15px;height: 15px;border-width: 1px;border-style: solid;border-color: white;opacity: 0.9;vertical-align: top;color: rgb(255, 255, 255);background-color: rgb(172, 29, 16);box-sizing: border-box !important;word-wrap: break-word !important;\"><\/section>\n<\/section>\n<section style=\"margin-top: 3px;margin-left: -33px;max-width: 100%;font-size: 0px;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 16px;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;display: inline-block;width: 10px;height: 10px;opacity: 0.6;color: rgb(255, 255, 255);background-color: rgb(172, 29, 16);\"><\/span><span style=\"margin-bottom: -10px;max-width: 100%;width: 6px;height: 6px;display: inline-block;color: rgb(255, 255, 255);background-color: rgb(172, 29, 16);\"><\/span>&nbsp; &nbsp;<\/span><\/section>\n<\/section>\n<\/section>\n<p style=\"white-space: normal;max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);text-align: center;\"><span style=\"max-width: 100%;font-size: 16px;color: rgb(123, 12, 0);box-sizing: border-box !important;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;text-align: justify;box-sizing: border-box !important;word-wrap: break-word !important;\">\u72ec\u7279\u7684\u5bb6\u5ead\u4e4b\u7a00\u6709\u751f\u7269<\/span><\/strong><\/span><\/p>\n<p style=\"text-align: justify;line-height: 1.75em;\"><br  \/><\/p>\n<p style=\"text-align: justify;line-height: 1.75em;\">\u90a3\u4e48\uff0c\u8fd9\u6837\u7684\u7814\u7a76\u5728\u8d85\u51fa\u8fd9\u7c7b\u5bb6\u5ead\u4e4b\u5916\u5230\u5e95\u6709\u4f55\u610f\u4e49\u5462\uff1f\u663e\u7136\uff0c\u8fd9\u4e00\u53d1\u73b0\u5177\u6709\u8f6c\u79fb\u4ef7\u503c\uff0c\u6709\u52a9\u4e8e\u89e3\u91ca\u5176\u4ed6\u75be\u75c5\u7684\u76f8\u5e94\u7a81\u53d8\u53d8\u5316\u3002\u201c\u8fd9\u662f\u81ea\u76f8\u77db\u76fe\u7684\uff0c\u5728\u8fd9\u79cd\u75c5\u56e0\u4e0b\uff0c\u4e00\u4e2a\u78b1\u57fa\u7684\u4e22\u5931\u5374\u5bfc\u81f4\u4e86\u4ea7\u91cf\u7684\u589e\u52a0\u3002\u201dWaage\u8bf4\u3002<\/p>\n<p><br  \/><\/p>\n<p style=\"text-align: justify;line-height: 1.75em;\">\u201c25\u5e74\u540e\uff0c\u6211\u4eec\u53d1\u73b0\u4e86\u5bfc\u81f4\u8fd9\u79cd\u60c5\u51b5\u7684\u7a81\u53d8\uff1b35\u5e74\u540e\uff0c\u6211\u4eec\u53ef\u4ee5\u89e3\u91ca\u4e3a\u4ec0\u4e48\u8fd9\u79cd\u7a81\u53d8\u4f1a\u5bfc\u81f4\u7ea2\u7ec6\u80de\u751f\u6210\u589e\u52a0\u3002\u8fd9\u4e00\u8def\u4e0a\uff0c\u6211\u4eec\u9047\u5230\u4e86\u4e00\u4f4d\u82ac\u5170\u6ed1\u96ea\u8005\uff0c\u52a0\u901f\u4e86\u6211\u4eec\u5bfb\u627e\u7b54\u6848\u7684\u6b65\u4f10\u3002\u8fd9\u662f\u4e00\u6b21\u574e\u5777\u800c\u6709\u8da3\u7684\u65c5\u7a0b\uff0c\u6240\u5e78\u6700\u7ec8\u83b7\u5f97\u4e86\u56de\u62a5\u3002\u201d Waage\u8bf4\uff0c\u201c\u81f3\u6b64\uff0cTr\u00f8ndelag\u8840\u6db2\u4e4b\u8c1c\u4e5f\u6b63\u5f0f\u5ba3\u5e03\u544a\u7834\u3002\u201d<\/p>\n<p><br  \/><\/p>\n<p style=\"text-align: justify;line-height: 1.75em;\">\u4ee5\u4e0a\u6210\u679c\u4ee5\u201cA Gain-of-Function Mutation in EPO in Familial Erythrocytosis\u201d\u4e3a\u9898\uff0c\u53d1\u8868\u5728\u9876\u7ea7\u533b\u5b66\u671f\u520aNew England Journal of Medicine\u6742\u5fd7\u4e0a\u3002<\/p>\n<section class=\"\"  style=\"white-space: normal;max-width: 100%;color: rgb(51, 51, 51);\">\n<section style=\"margin: 10px auto;max-width: 100%;text-align: center;box-sizing: border-box !important;word-wrap: break-word !important;\">\n<section style=\"margin-bottom: 3px;margin-left: 33px;max-width: 100%;font-size: 0px;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 16px;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"margin-bottom: 10px;max-width: 100%;width: 6px;height: 6px;display: inline-block;color: rgb(255, 255, 255);background-color: rgb(172, 29, 16);\"><\/span><span style=\"max-width: 100%;display: inline-block;width: 10px;height: 10px;opacity: 0.6;color: rgb(255, 255, 255);background-color: rgb(172, 29, 16);\"><\/span>&nbsp;&nbsp;&nbsp;<\/span><\/section>\n<section style=\"margin-top: -2px;max-width: 100%;font-size: 0px;box-sizing: border-box !important;word-wrap: break-word !important;\">\n<section style=\"display: inline-block;max-width: 100%;width: 15px;height: 15px;border-width: 1px;border-style: solid;border-color: white;opacity: 0.9;vertical-align: bottom;color: rgb(255, 255, 255);background-color: rgb(172, 29, 16);box-sizing: border-box !important;word-wrap: break-word !important;\"><\/section>\n<section style=\"display: inline-block;max-width: 100%;border-width: 1px;border-style: solid;border-color: rgb(255, 255, 255);width: 30px;height: 30px;line-height: 30px;vertical-align: top;color: rgb(255, 255, 255);background-color: rgb(172, 29, 16);box-sizing: border-box !important;word-wrap: break-word !important;\">\n<p class=\"\" style=\"margin-right: auto;margin-left: auto;max-width: 100%;min-height: 1em;white-space: pre-wrap;min-width: 1px;font-size: 16px;box-sizing: border-box !important;word-wrap: break-word !important;\">06<\/p>\n<\/section>\n<section style=\"display: inline-block;max-width: 100%;width: 15px;height: 15px;border-width: 1px;border-style: solid;border-color: white;opacity: 0.9;vertical-align: top;color: rgb(255, 255, 255);background-color: rgb(172, 29, 16);box-sizing: border-box !important;word-wrap: break-word !important;\"><\/section>\n<\/section>\n<section style=\"margin-top: 3px;margin-left: -33px;max-width: 100%;font-size: 0px;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 16px;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;display: inline-block;width: 10px;height: 10px;opacity: 0.6;color: rgb(255, 255, 255);background-color: rgb(172, 29, 16);\"><\/span><span style=\"margin-bottom: -10px;max-width: 100%;width: 6px;height: 6px;display: inline-block;color: rgb(255, 255, 255);background-color: rgb(172, 29, 16);\"><\/span>&nbsp; &nbsp;<\/span><\/section>\n<\/section>\n<\/section>\n<p style=\"white-space: normal;max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);text-align: center;\"><span style=\"max-width: 100%;font-size: 16px;color: rgb(123, 12, 0);box-sizing: border-box !important;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;text-align: justify;box-sizing: border-box !important;word-wrap: break-word !important;\">\u5f71\u54cd\u5065\u5eb7\uff1f<\/span><\/strong><\/span><\/p>\n<p style=\"text-align: justify;line-height: 1.75em;\"><br  \/><\/p>\n<p style=\"text-align: justify;line-height: 1.75em;\">\u5bf9\u4e8e\u53d7\u5f71\u54cd\u7684\u5bb6\u5ead\u6210\u5458\u6765\u8bf4\uff0c\u8fd9\u79cd\u7a81\u53d8\u4e0d\u4f1a\u5bfc\u81f4\u75be\u75c5\uff0c\u4f46\u53ef\u80fd\u4f1a\u5f15\u53d1\u4e00\u79cd\u5e38\u89c1\u7684\u5934\u75db\u75c7\u72b6\uff0c\u800c\u8be5\u75c7\u72b6\u53ef\u901a\u8fc7\u4f20\u7edf\u7684\u653e\u8840\u8fdb\u884c\u6cbb\u7597\u3002\u4e00\u65e6\u8fc7\u91cf\u7684\u8840\u6db2\u88ab\u6e05\u9664\uff0c\u4ed6\u4eec\u5c31\u4f1a\u611f\u89c9\u826f\u597d\u3002<\/p>\n<p><br  \/><\/p>\n<p style=\"text-align: justify;line-height: 1.75em;\">\u90a3\u4e48\u4ed6\u4eec\u7684\u4f53\u8d28\u600e\u4e48\u6837\u5462\uff1f\u8ba9\u79d1\u7814\u4eba\u5458\u611f\u5230\u5947\u602a\u7684\u662f\uff0c\u51fa\u751f\u65f6Hb\u6c34\u5e73\u5c31\u9ad8\u7684\u60a3\u8005\u4e0e\u901a\u8fc7\u5174\u594b\u5242\u4f7fHb\u6c34\u5e73\u5347\u9ad8\u7684\u4eba\u662f\u4e0d\u540c\u7684\u3002\u6beb\u65e0\u7591\u95ee\uff0c<strong>\u7528\u989d\u5916\u7684EPO\u589e\u52a0Hb\u6c34\u5e73\u5bf9\u4e8e\u63d0\u9ad8\u5065\u5eb7\u6c34\u5e73\u662f\u975e\u5e38\u6709\u6548\u7684\u3002<\/strong>\u4f46\u662f\uff0c\u51fa\u751f\u65f6\u5c31\u62e5\u6709\u9ad8\u6c34\u5e73EPO\u548c Hb\u7684\u4eba\u5e76\u6ca1\u6709\u83b7\u5f97\u989d\u5916\u7684\u5065\u5eb7\u4fc3\u8fdb\u6548\u679c\u3002<\/p>\n<p style=\"text-align: justify;line-height: 1.75em;\"><br  \/><\/p>\n<p style=\"text-align: right;line-height: 1.75em;\"><strong>\u8d23\u7f16\uff1a\u827e\u66fc<\/strong><\/p>\n<section  class=\"\" style=\"white-space: normal;max-width: 100%;color: rgb(51, 51, 51);\">\n<section  style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\">\n<section  class=\"\" style=\"max-width: 100%;line-height: 28.4444px;font-family: \u5fae\u8f6f\u96c5\u9ed1;border-width: 0px;border-style: none;border-color: initial;box-sizing: border-box !important;word-wrap: break-word !important;overflow-wrap: break-word !important;\">\n<section  style=\"margin: 1em auto;max-width: 100%;border-width: 0px;border-style: none;border-color: initial;text-align: center;width: 941px;box-sizing: border-box !important;word-wrap: break-word !important;overflow-wrap: break-word !important;\"><span class=\"\"  style=\"max-width: 100%;width: 941px;border-bottom: 1px solid rgb(172, 29, 16);border-top-color: rgb(172, 29, 16);border-right-color: rgb(172, 29, 16);border-left-color: rgb(172, 29, 16);display: inline-block;box-sizing: border-box !important;word-wrap: break-word !important;overflow-wrap: break-word !important;\"><\/p>\n<section class=\"\" style=\"margin-bottom: -3px;padding-top: 5px;padding-right: 10px;padding-left: 10px;display: inline-block;max-width: 100%;min-height: 32px;border-bottom: 5px solid rgb(172, 29, 16);font-size: 20px;color: rgb(121, 121, 121);box-sizing: border-box !important;word-wrap: break-word !important;overflow-wrap: break-word !important;\">\n<p class=\"\" style=\"margin-top: 5px;margin-bottom: 5px;max-width: 100%;min-height: 1em;line-height: 1.6em;font-size: 16px;box-sizing: border-box !important;word-wrap: break-word !important;overflow-wrap: break-word !important;\">End<\/p>\n<\/section>\n<p><\/span><\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<p class=\"bizsvr_49\" style=\"white-space: normal;max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><strong class=\"bizsvr_19\" style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"><span class=\"bizsvr_51\" style=\"max-width: 100%;font-size: 12px;box-sizing: border-box !important;word-wrap: break-word !important;\">\u53c2\u8003\u8d44\u6599\uff1a<\/span><\/strong><span style=\"max-width: 100%;font-size: 12px;box-sizing: border-box !important;word-wrap: break-word !important;\">1\uff09<\/span><span style=\"font-size: 12px;text-align: justify;\">Family blood mystery solved<\/span><\/p>\n<p style=\"white-space: normal;text-align: justify;line-height: 1.75em;\"><span style=\"font-size: 12px;\">2\uff09A Gain-of-Function Mutation in EPO in Familial Erythrocytosis<\/span><\/p>\n<p class=\"bizsvr_49\" style=\"white-space: normal;max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><span style=\"max-width: 100%;font-size: 12px;box-sizing: border-box !important;word-wrap: break-word !important;\"><\/span><\/p>\n<section  class=\"\" style=\"font-size: 16px;white-space: normal;max-width: 100%;box-sizing: border-box;text-align: justify;background-color: rgb(255, 255, 255);letter-spacing: 0.544px;color: rgb(62, 62, 62);line-height: 25.6px;font-family: \u5fae\u8f6f\u96c5\u9ed1;border-width: 0px;border-style: none;word-wrap: break-word !important;overflow-wrap: break-word !important;\">\n<section class=\"\"  style=\"padding: 2px;max-width: 100%;box-sizing: border-box;border-width: 1px;border-style: dotted;border-color: rgb(218, 98, 71);word-wrap: break-word !important;overflow-wrap: break-word !important;\">\n<section class=\"\" style=\"margin: 5px auto;max-width: 100%;box-sizing: border-box;border-width: 0px;border-style: none;word-wrap: break-word !important;overflow-wrap: break-word !important;\">\n<section class=\"bizsvr_60\" style=\"max-width: 100%;box-sizing: border-box;height: 25px;color: inherit;word-wrap: break-word !important;overflow-wrap: break-word !important;\">\n<section class=\"bizsvr_61\" style=\"max-width: 100%;box-sizing: border-box;height: 25px;width: 50px;float: left;border-top: 2px solid rgb(172, 29, 16);border-right-color: rgb(172, 29, 16);border-bottom-color: rgb(172, 29, 16);border-left: 2px solid rgb(172, 29, 16);color: inherit;word-wrap: break-word !important;overflow-wrap: break-word !important;\"><\/section>\n<section class=\"bizsvr_62\" style=\"display: inline-block;max-width: 100%;box-sizing: border-box;color: rgb(172, 29, 16);clear: both;border-color: rgb(172, 29, 16);word-wrap: break-word !important;overflow-wrap: break-word !important;\"><\/section>\n<\/section>\n<section class=\"\"  style=\"margin: -0.8em 0.3em;padding: 0.8em;max-width: 100%;box-sizing: border-box;color: inherit;word-wrap: break-word !important;overflow-wrap: break-word !important;\">\n<p class=\"bizsvr_63\" style=\"max-width: 100%;min-height: 1em;overflow-wrap: break-word;color: rgb(51, 51, 51);font-size: 1em;line-height: 1.75em;word-break: break-all;box-sizing: border-box !important;word-wrap: break-word !important;\"><span class=\"bizsvr_64\" style=\"max-width: 100%;color: rgb(0, 0, 0);line-height: 22.4px;font-size: 14px;box-sizing: border-box !important;word-wrap: break-word !important;overflow-wrap: break-word !important;\">\u672c\u6587\u7cfb\u751f\u7269\u63a2\u7d22\u539f\u521b\uff0c\u6b22\u8fce\u4e2a\u4eba\u8f6c\u53d1\u5206\u4eab\u3002\u5176\u4ed6\u4efb\u4f55\u5a92\u4f53\u3001\u7f51\u7ad9\u5982\u9700\u8f6c\u8f7d\uff0c\u987b\u5728\u6b63\u6587\u524d\u6ce8\u660e\u6765\u6e90\u751f\u7269\u63a2\u7d22\u3002<\/span><\/p>\n<\/section>\n<section class=\"bizsvr_65\" style=\"max-width: 100%;box-sizing: border-box;height: 25px;color: inherit;word-wrap: break-word !important;overflow-wrap: break-word !important;\">\n<section class=\"bizsvr_66\" style=\"max-width: 100%;box-sizing: border-box;height: 25px;width: 50px;float: right;border-bottom: 2px solid rgb(172, 29, 16);border-top-color: rgb(172, 29, 16);border-right: 2px solid rgb(172, 29, 16);border-left-color: rgb(172, 29, 16);color: inherit;word-wrap: break-word !important;overflow-wrap: break-word !important;\"><\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<p class=\"bizsvr_67\" style=\"white-space: normal;max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);text-align: center;\">\n<blockquote class='keep-source'>\n<p>\u59cb\u53d1\u4e8e\u5fae\u4fe1\u516c\u4f17\u53f7\uff1a                         \u751f\u7269\u63a2\u7d22                      <\/p>\n<\/blockquote>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>20\u4e16\u7eaa70\u5e74\u4ee3\u672b\uff0c\u4e00\u540d\u60c5\u51b5\u4e0d\u660e\u7684\u9ad8\u8840\u7ea2\u86cb\u767d\u6c34\u5e73\uff08hemoglobin level\uff0cHb\uff09\u7684\u7537\u5b50\u88ab\u9001\u5230\u4e86\u632a\u5a01N [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":10322,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[2],"tags":[],"_links":{"self":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/10321"}],"collection":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/comments?post=10321"}],"version-history":[{"count":1,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/10321\/revisions"}],"predecessor-version":[{"id":10324,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/10321\/revisions\/10324"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/media\/10322"}],"wp:attachment":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/media?parent=10321"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/categories?post=10321"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/tags?post=10321"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}