{"id":10423,"date":"2018-06-09T01:00:00","date_gmt":"2018-07-27T09:47:13","guid":{"rendered":"http:\/\/www.05921.net\/index.php\/2018\/07\/27\/%e7%bb%86%e8%83%9e%e6%b2%bb%e7%96%97%e5%b7%a5%e8%89%ba%e4%b8%ad%e7%9a%84%e8%b4%a8%e9%87%8f%e6%ba%90%e4%ba%8e%e8%ae%be%e8%ae%a1\/"},"modified":"2018-07-27T17:47:23","modified_gmt":"2018-07-27T09:47:23","slug":"%e7%bb%86%e8%83%9e%e6%b2%bb%e7%96%97%e5%b7%a5%e8%89%ba%e4%b8%ad%e7%9a%84%e8%b4%a8%e9%87%8f%e6%ba%90%e4%ba%8e%e8%ae%be%e8%ae%a1","status":"publish","type":"post","link":"https:\/\/www.05921.net\/index.php\/10423\/","title":{"rendered":"\u7ec6\u80de\u6cbb\u7597\u5de5\u827a\u4e2d\u7684\u8d28\u91cf\u6e90\u4e8e\u8bbe\u8ba1"},"content":{"rendered":"<div class=\"bpp-post-content\">\n<p style=\"margin-top: 1em;margin-bottom: 1em;max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);text-align: justify;\"><span style=\"font-size: 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style=\"margin-top: 1em;margin-bottom: 1em;max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);text-align: justify;\"><span style=\"font-size: 14px;\">2002\u5e74\uff0c\u7f8e\u56fdFDA\u5f15\u8fdb\u4e86cGMP\u5021\u8bae\u6765\u5e94\u5bf9\u836f\u7269\u751f\u4ea7\u5931\u8d25\u8ffd\u5bfb\u5176\u6f5c\u5728\u539f\u56e0\u65f6\u7684\u4f4e\u6548\u53ca\u6311\u6218\uff0c\u5e76\u57282006\u5e74\u56fd\u9645\u534f\u8c03\u4f1a\u8bae\u4e0a\u6982\u8ff0\u4e86QbD\u7684\u6846\u67b6\uff0c\u7528\u7cfb\u7edf\u7684\u65b9\u6cd5\u57fa\u4e8e\u79d1\u5b66\u77e5\u8bc6\u4e0e\u98ce\u9669\u8bc4\u4f30\u6765\u8fdb\u884c\u5de5\u827a\u548c\u4ea7\u54c1\u7ba1\u7406\u3002\u4eca\u5929\uff0c\u968f\u7740\u5c0f\u5206\u5b50\u5236\u836f\u751f\u4ea7\u5bf9QbD\u7684\u5e7f\u6cdb\u63a5\u53d7\uff0c\u8d8a\u6765\u8d8a\u591a\u7684\u751f\u7269\u5236\u836f\u751f\u4ea7\u4e5f\u5f00\u59cb\u5c06QbD\u539f\u5219\u8d2f\u5f7b\u5230\u5b83\u4eec\u7684\u5de5\u827a\u4e2d\u3002\u867d\u7136\u4e00\u4e9b\u76d1\u7ba1\u673a\u6784\uff0c\u5982Health Canada,&nbsp;\u76ee\u524d\u53ea\u63a5\u53d7\u4e86\u9488\u5bf9\u4e8e\u5178\u578b\u5316\u836f\u548c\u751f\u7269\u836f\u7684\u4ee5QbD\u4e3a\u57fa\u7840\u7684\u5efa\u8bae\u4e66\uff0c\u800c\u5728\u7ec6\u80de\u4e3a\u57fa\u7840\u7684\u6cbb\u7597\u65b9\u6cd5\u4e2d\u4f7f\u7528QbD\u53ef\u4ee5\u6781\u5927\u7684\u63d0\u9ad8\u5bf9\u5de5\u827a\u548c\u4ea7\u54c1\u7684\u7406\u89e3\u548c\u4ea7\u51fa\u3002\u4e8b\u5b9e\u4e0a\uff0c\u7ec6\u80de\u6cbb\u7597\u4ea7\u54c1\u7684\u751f\u7269\u590d\u6742\u6027\u4f7fQbD\u7684\u8fed\u4ee3\u539f\u5219\u5c24\u4e3a\u8d34\u8fd1\u4e8e\u8fd9\u79cd\u6cbb\u7597\u65b9\u5f0f\u3002<\/span><\/p>\n<p style=\"margin-top: 1em;margin-bottom: 1em;max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);text-align: justify;\"><span style=\"font-size: 14px;\">\u8fd9\u91cc\u6211\u4eec\u56de\u987e\u4e86\u4e3b\u8981\u7684QbD\u6982\u5ff5\uff08BOX 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title=\"\u7ec6\u80de\u6cbb\u7597\u5de5\u827a\u4e2d\u7684\u8d28\u91cf\u6e90\u4e8e\u8bbe\u8ba1\"  \/><\/p>\n<p style=\"margin-top: 1em;margin-bottom: 1em;max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);text-align: justify;\"><span style=\"font-size: 14px;\">\u8fd9\u56db\u79cd\u7ec6\u80de\u6cbb\u7597\u4ea7\u54c1\u5438\u5f15\u4e86\u4f17\u591a\u533b\u836f\u516c\u53f8\u4e89\u76f8\u6295\u8d44\u3002\u5728\u65b0\u5174\u7684PSC\u8bf1\u5bfc\u7684\u6cbb\u7597\u65b9\u6cd5\u4e2d\uff0cOcata Theerapeutics (\u7f8e\u56fd)\u516c\u53f8\u9488\u5bf9\u81f4\u76f2\u75c7\u7684PSC\u8bf1\u5bfc\u89c6\u7f51\u819c\u7ec6\u80de\u7597\u6cd5\u5df2\u7ecf\u8fdb\u5165\u4e34\u5e8a\u5b9e\u9a8c\uff0c\u76ee\u524d\u5df2\u7ecf\u88abAstellas Pharma(\u4e1c\u4eac)\u516c\u53f8\u4ee53.79\u4ebf\u7f8e\u5143\u6536\u8d2d\uff0cNovartis(\u745e\u58eb)\u516c\u53f8\u6295\u8d44\u4e863500\u4e07\u7f8e\u5143\u7ed9Gamida 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Therapeutics(\u897f\u96c5\u56fe)\u5408\u4f5c\u4e0e\u6536\u8d2d\u7684\u4e3b\u9898\u3002\u7136\u800c\u5373\u4f7f\u8fd9\u4e9b\u6216\u5176\u5b83\u7684\u7ec6\u80de\u7597\u6cd5\u5df2\u7ecf\u6709\u4e86\u4ee4\u4eba\u5174\u594b\u7684\u4e34\u5e8a\u8fdb\u5c55\uff0c\u4f46\u751f\u4ea7\u4e2d\u4ecd\u6709\u8bb8\u591a\u6311\u6218\u9700\u8981\u514b\u670d\u3002QbD\u63d0\u4f9b\u4e86\u4e00\u4e2a\u5408\u7406\u7684\u6846\u67b6\u6765\u5e94\u5bf9\u8fd9\u4e9b\u6311\u6218\u5e76\u4fc3\u8fdb\u7ec6\u80de\u7597\u6cd5\u4f5c\u4e3a\u4e00\u79cd\u5e38\u89c4\u6cbb\u7597\u9009\u62e9\u7684\u5b9e\u73b0\u3002\u5982\u679c\u8fd9\u4e9b\u6311\u6218\u4e0d\u88ab\u89e3\u51b3\u5c06\u5bfc\u81f4\u5168\u884c\u4e1a\u90fd\u65e0\u6cd5\u5b9e\u73b0\u5728\u53ef\u63a7\u6210\u672c\u6761\u4ef6\u4e0b\u751f\u4ea7\u51fa\u9ad8\u8d28\u91cf\u7684\u4ea7\u54c1\uff0c\u4e5f\u4f1a\u5f71\u54cd\u5168\u7403\u8303\u56f4\u5185&gt;600\u4e2a\u518d\u751f\u533b\u5b66\u4e34\u5e8a\u5b9e\u9a8c\u7684\u4ea7\u4e1a\u5316\u3002<\/span><\/p>\n<p style=\"text-align:center;\"><img loading=\"lazy\" class=\"\"    height=\"347.20001220703125\" style=\"vertical-align: top;box-sizing: border-box !important;word-wrap: break-word !important;width: auto !important;visibility: visible !important;\" width=\"402.2699890136719\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/07\/beepress0-1532684838.png\" alt=\"\u7ec6\u80de\u6cbb\u7597\u5de5\u827a\u4e2d\u7684\u8d28\u91cf\u6e90\u4e8e\u8bbe\u8ba1\" title=\"\u7ec6\u80de\u6cbb\u7597\u5de5\u827a\u4e2d\u7684\u8d28\u91cf\u6e90\u4e8e\u8bbe\u8ba1\"  \/><\/p>\n<h3 style=\"font-weight: bold;max-width: 100%;color: rgb(51, 51, 51);text-align: justify;\"><span style=\"max-width: 100%;font-size: 14px;box-sizing: border-box !important;word-wrap: break-word !important;\"><\/span><\/h3>\n<section class=\"\"   style=\"max-width: 100%;box-sizing: border-box;color: rgb(51, 51, 51);\">\n<section class=\"\"   placeholder=\"\u6d45\u8272\u8fb9\u6846\u6807\u9898\" style=\"margin-top: 10px;margin-bottom: 10px;padding: 10px;max-width: 100%;box-sizing: border-box;line-height: 25px;color: rgb(254, 254, 254);font-weight: bold;box-shadow: rgb(153, 153, 153) 1px 1px 2px;border-left: 25px solid rgb(208, 168, 228);border-top-color: rgb(208, 168, 228);border-right-color: rgb(208, 168, 228);border-bottom-color: rgb(208, 168, 228);background-color: rgb(166, 91, 203);word-wrap: break-word !important;text-align: justify;\"><span style=\"font-size: 14px;\">\u5e94\u7528QbD\u8fdb\u884c\u7ec6\u80de\u751f\u4ea7<\/span><\/section>\n<\/section>\n<h3 style=\"font-weight: bold;max-width: 100%;color: rgb(51, 51, 51);text-align: justify;\"><span style=\"max-width: 100%;font-size: 14px;box-sizing: border-box !important;word-wrap: break-word !important;\"><\/span><\/h3>\n<p style=\"margin-top: 1em;margin-bottom: 1em;max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);text-align: justify;\"><span style=\"font-size: 14px;\">\u751f\u7269\u53cd\u5e94\u5668\u7cfb\u7edf\u56e0\u5176\u53ef\u89c4\u6a21\u5316\uff0c\u6613\u4e8e\u96c6\u6210\u68c0\u6d4b\u6280\u672f\u53ca\u53ef\u4ee5\u81ea\u52a8\u54cd\u5e94\u6765\u7ef4\u6301\u73af\u5883\u5747\u4e00\u6027\u7b49\u7279\u70b9\uff0c\u6210\u4e3a\u751f\u4ea7\u6cbb\u7597\u578b\u86cb\u767d\u6240\u9700\u7684\u7ec6\u80de\u57f9\u517b\u65b9\u6cd5\u3002\u7136\u800c\uff0c\u8fd9\u4e9b\u7cfb\u7edf\u662f\u4e3a\u4e86\u83b7\u5f97\u9ad8\u86cb\u767d\u4ea7\u91cf\u800c\u8bbe\u8ba1\u7684\uff0c\u800c\u4e0d\u4f1a\u4f18\u5148\u8003\u8651\u7ec6\u80de\u672c\u8eab\u3002\u76f8\u6bd4\u4e4b\u4e0b,\u7ec6\u80de\u6cbb\u7597\u4ea7\u54c1\u751f\u4ea7\u8fc7\u7a0b\u4e2d\u751f\u4ea7\u51fa\u7684\u5065\u5eb7\u7684\u529f\u80fd\u7ec6\u80de\u5bf9\u73af\u5883\u56e0\u7d20\u6709\u9ad8\u5ea6\u7684\u654f\u611f\u6027\u3002\u8bb8\u591a\u751f\u7269\u53cd\u5e94\u5668\u7c7b\u578b\uff0c\u7ec6\u80de\u751f\u4ea7\u6a21\u5f0f\uff0c\u89c4\u6a21\u548c\u63a7\u5236\u53c2\u6570\u76ee\u524d\u5df2\u7ecf\u53ef\u4ee5\u5e94\u7528\u4e8e\u7ec6\u80de\u6cbb\u7597\u4ea7\u54c1\u751f\u4ea7\u4e2d(\u56fe1)\u3002\u4e86\u89e3\u8fd9\u4e9b\u4e0d\u540c\u7684\u201c\u6a21\u5757\u201d\u7684\u6027\u80fd\u548c\u5b83\u4eec\u5982\u4f55\u5e94\u7528\u4e8e\u7ec6\u80de\u6cbb\u7597\u4ea7\u54c1\u751f\u4ea7\u5bf9\u4e8eQbD\u662f\u81f3\u5173\u91cd\u8981\u7684\uff0c\u76f8\u53cd\u4e5f\u53ef\u4ee5\u5e94\u7528QbD\u66f4\u6df1\u5165\u4e86\u89e3\u4ee5\u4e0a\u8981\u70b9\u3002<\/span><\/p>\n<p style=\"text-align:center;\"><span style=\"max-width: 100%;line-height: 24px;font-size: 14px;box-sizing: border-box !important;word-wrap: break-word !important;\"><img loading=\"lazy\" class=\"\"    height=\"399.92999267578125\" style=\"vertical-align: top;box-sizing: border-box !important;word-wrap: break-word !important;width: auto !important;visibility: visible !important;\" width=\"490.92999267578125\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/07\/beepress5-1532684838.png\" alt=\"\u7ec6\u80de\u6cbb\u7597\u5de5\u827a\u4e2d\u7684\u8d28\u91cf\u6e90\u4e8e\u8bbe\u8ba1\" title=\"\u7ec6\u80de\u6cbb\u7597\u5de5\u827a\u4e2d\u7684\u8d28\u91cf\u6e90\u4e8e\u8bbe\u8ba1\"  \/><\/span><\/p>\n<p style=\"margin-top: 1em;margin-bottom: 1em;max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);text-align: justify;\"><span style=\"font-size: 14px;\">&nbsp;&nbsp;QbD\u5305\u62ec\u4ea7\u54c1\u548c\u5de5\u827a\u63cf\u8ff0\uff0c\u8868\u5f81\uff0c\u8bbe\u8ba1\uff0c\u76d1\u63a7\u548c\u6301\u7eed\u6539\u8fdb(\u56fe2)\u3002\u800c\u8fd9\u4e9b\u90fd\u7531\u5bf9\u57fa\u672c\u751f\u7269\u5b66\u548c\u67d0\u4e00\u4ea7\u54c1\u53ca\u5176\u5de5\u827a\u5de5\u7a0b\u7684\u6df1\u5165\u4e86\u89e3\u6765\u6307\u5bfc\u3002<\/span><\/p>\n<p style=\"text-align:center;\"><img loading=\"lazy\" class=\"\"    height=\"452.3299865722656\" style=\"vertical-align: top;box-sizing: border-box !important;word-wrap: break-word !important;width: auto !important;visibility: visible !important;\" width=\"553.0700073242188\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/07\/beepress9-1532684842.png\" alt=\"\u7ec6\u80de\u6cbb\u7597\u5de5\u827a\u4e2d\u7684\u8d28\u91cf\u6e90\u4e8e\u8bbe\u8ba1\" title=\"\u7ec6\u80de\u6cbb\u7597\u5de5\u827a\u4e2d\u7684\u8d28\u91cf\u6e90\u4e8e\u8bbe\u8ba1\"  \/><\/p>\n<p style=\"margin-top: 1em;margin-bottom: 1em;max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);text-align: justify;\"><span style=\"font-size: 14px;\">QbD\u7531\u76ee\u6807\u4ea7\u54c1\u8d28\u91cf\u6982\u51b5(\u76ee\u6807\u4ea7\u54c1\u7684\u8d28\u91cf\u6307\u6807; QTPP)\uff0c\u76f4\u63a5\u5f71\u54cd\u4ea7\u54c1\u5b89\u5168\u6027\u548c\u6709\u6548\u6027\u7684\u5b9a\u4e49\u5c5e\u6027(\u5173\u952e\u8d28\u91cf\u5c5e\u6027)\uff0c\u901a\u8fc7\u5b9a\u4e49\u8fd9\u4e9b\u4f1a\u5f71\u54cd\u6027\u80fd\u7684\u53c2\u6570(\u5173\u952e\u8fc7\u7a0b\u53c2\u6570)\u548c\u5efa\u7acb\u8bbe\u8ba1\u7a7a\u95f4\u6765\u9650\u5236\u5f71\u54cd\u8d28\u91cf\u5c5e\u6027\u7684\u53c2\u6570\u53d8\u5f02\u3002\u63a5\u4e0b\u6765\uff0c\u5f00\u53d1\u63a7\u5236\u7b56\u7565\u6765\u4fdd\u6301\u8fc7\u7a0b\u53c2\u6570\u5728\u4e00\u4e2a\u8303\u56f4\u5185\u6765\u786e\u4fdd\u4ea7\u54c1\u8d28\u91cf\uff0c\u5e76\u4e14\u5728\u653e\u5927\u8fc7\u7a0b\u4e2d\u8fdb\u884c\u5de5\u827a\u9a8c\u8bc1\u3002\u76f8\u5bf9\u4e8e\u4f20\u7edf\u7684\u57fa\u4e8e\u79bb\u6563\u70b9\u7684\u63a7\u5236\u7b56\u7565\uff0cQbD\u6807\u8bc6\u4e86\u4e00\u4e2a\u53ef\u4ee5\u751f\u4ea7\u51fa\u9ad8\u8d28\u91cf\u4ea7\u54c1\u7684\u53ef\u4ee5\u63a5\u53d7\u7684\u64cd\u4f5c\u533a\u57df\u6216\u591a\u5143\u8bbe\u8ba1\u7a7a\u95f4\u3002\u4e00\u65e6\u5b9e\u65bd\uff0c\u8fd9\u4e2a\u751f\u4ea7\u5de5\u827a\u88ab\u76d1\u63a7\u4e14\u968f\u7740\u5bf9\u5de5\u827a\u7684\u6df1\u5165\u7406\u89e3\u53ef\u4ee5\u88ab\u4e0d\u65ad\u6539\u8fdb(\u56fe3)\u3002<\/span><\/p>\n<p style=\"margin-top: 1em;margin-bottom: 1em;max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);text-align: justify;\"><img loading=\"lazy\" class=\"\"    height=\"281.3999938964844\" style=\"vertical-align: top;box-sizing: border-box !important;word-wrap: break-word !important;width: auto !important;visibility: visible !important;\" width=\"553.72998046875\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/07\/beepress4-1532684843.png\" alt=\"\u7ec6\u80de\u6cbb\u7597\u5de5\u827a\u4e2d\u7684\u8d28\u91cf\u6e90\u4e8e\u8bbe\u8ba1\" title=\"\u7ec6\u80de\u6cbb\u7597\u5de5\u827a\u4e2d\u7684\u8d28\u91cf\u6e90\u4e8e\u8bbe\u8ba1\"  \/><img class=\"\"      style=\"font-size: 16px;box-sizing: border-box !important;word-wrap: break-word !important;width: auto !important;visibility: visible !important;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/07\/beepress10-1532684843.jpg\" alt=\"\u7ec6\u80de\u6cbb\u7597\u5de5\u827a\u4e2d\u7684\u8d28\u91cf\u6e90\u4e8e\u8bbe\u8ba1\" title=\"\u7ec6\u80de\u6cbb\u7597\u5de5\u827a\u4e2d\u7684\u8d28\u91cf\u6e90\u4e8e\u8bbe\u8ba1\"  \/><\/p>\n<h2 style=\"font-weight: bold;max-width: 100%;color: rgb(51, 51, 51);\"><\/h2>\n<section class=\"\"   style=\"max-width: 100%;box-sizing: border-box;color: rgb(51, 51, 51);\">\n<section class=\"\"   placeholder=\"\u6d45\u8272\u8fb9\u6846\u6807\u9898\" style=\"margin-top: 10px;margin-bottom: 10px;padding: 10px;max-width: 100%;box-sizing: border-box;line-height: 25px;color: rgb(254, 254, 254);font-weight: bold;box-shadow: rgb(153, 153, 153) 1px 1px 2px;border-left: 25px solid rgb(208, 168, 228);border-top-color: rgb(208, 168, 228);border-right-color: rgb(208, 168, 228);border-bottom-color: rgb(208, 168, 228);background-color: rgb(166, 91, 203);word-wrap: break-word !important;text-align: justify;\"><span style=\"font-size: 14px;\">\u76ee\u6807\u4ea7\u54c1\u8d28\u91cf\u6982\u51b5(QTPP)<\/span><\/section>\n<\/section>\n<h2 style=\"font-weight: bold;max-width: 100%;color: rgb(51, 51, 51);text-align: justify;\"><span style=\"max-width: 100%;font-size: 14px;box-sizing: border-box !important;word-wrap: break-word !important;\"><\/span><\/h2>\n<p style=\"margin-top: 1em;margin-bottom: 1em;max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);text-align: justify;\"><span style=\"font-size: 14px;\">QTPP\u63cf\u8ff0\u4e86\u6240\u9700\u7ec8\u4ea7\u54c1\u7684\u5c5e\u6027\uff0c\u5982\u4e00\u81f4\u6027\uff0c\u6548\u529b\u548c\u7eaf\u5ea6\uff0c\u8fd9\u4e5f\u662fQbD\u7684\u8d77\u70b9\u3002\u6211\u4eec\u5c55\u793a\u4e86\u56db\u4e2a\u7ec6\u80de\u6cbb\u7597\u4ea7\u54c1\u7684QTPP\u4f5c\u4e3a\u4e3e\u4f8b(\u56fe2)\u3002\u91cd\u8981\u7684\u662f\uff0c\u6bcf\u4e2a\u7ec6\u80de\u6cbb\u7597\u4ea7\u54c1\u7684\u4e00\u81f4\u6027\uff0c\u6548\u529b\u548c\u7eaf\u5ea6\u7684\u5b9a\u4e49\u53d6\u51b3\u4e8e\u5404\u81ea\u4f7f\u7528\u7684\u7597\u6cd5\u3002\u5b9a\u4e49\u4e25\u683c\uff0c\u6807\u51c6\u5bb9\u6613\u8861\u91cf\u662f\u5efa\u7acbQTPP\u7684\u5173\u952e\u3002<\/span><\/p>\n<p style=\"margin-top: 1em;margin-bottom: 1em;max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);text-align: justify;\"><span style=\"font-size: 14px;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\">\u9274\u5b9a 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style=\"font-size: 14px;max-width: 100%;line-height: 24px;box-sizing: border-box !important;word-wrap: break-word !important;\">\u53d8<\/span>\u56e0\u7d20\u3002\u4f8b\u5982\uff0c\u4e8c\u7532\u57fa\u4e9a\u781c\uff0c\u5e38\u7528\u7684\u51b7\u51bb\u4fdd\u62a4\u5242\uff0c\u53ef\u4ee5\u589e\u52a0\u589e\u5851\u5242\u4ece\u751f\u7269\u53cd\u5e94\u5668\u7ba1\u9053\u4e2d\u6d78\u51fa\uff0c\u548cpH\u503c\u6307\u6807\u53ef\u4ee5\u5f71\u54cd\u7ec6\u80de\u7684\u5206\u5316\u3002\u56e0\u6b64\uff0c\u8d28\u91cf\u76ee\u6807\u4ea7\u54c1\u914d\u7f6e\u6587\u4ef6\u5fc5\u987b\u63cf\u8ff0\u8fd9\u4e9b\u8f85\u52a9\u6750\u6599\u5728\u6700\u7ec8\u4ea7\u54c1\u4e2d\u7684\u6700\u5927\u6b8b\u7559\u6c34\u5e73\u4ee5\u786e\u4fdd\u5176\u5b89\u5168\u6027\uff0c\u800c\u4e14\u9700\u8981\u6709\u989d\u5916\u7684\u5904\u7406\u4ee5\u514d\u5f71\u54cd\u6700\u7ec8\u7684\u7ec6\u80de\u4ea7\u91cf\u3002<\/span><\/p>\n<h2 style=\"font-weight: bold;max-width: 100%;color: rgb(51, 51, 51);text-align: justify;\"><span style=\"max-width: 100%;font-size: 14px;box-sizing: border-box !important;word-wrap: break-word !important;\"><\/span><\/h2>\n<section class=\"\"   style=\"max-width: 100%;box-sizing: border-box;color: rgb(51, 51, 51);\">\n<section class=\"\"   placeholder=\"\u6d45\u8272\u8fb9\u6846\u6807\u9898\" style=\"margin-top: 10px;margin-bottom: 10px;padding: 10px;max-width: 100%;box-sizing: border-box;line-height: 25px;color: rgb(254, 254, 254);font-weight: bold;box-shadow: rgb(153, 153, 153) 1px 1px 2px;border-left: 25px solid rgb(208, 168, 228);border-top-color: rgb(208, 168, 228);border-right-color: rgb(208, 168, 228);border-bottom-color: rgb(208, 168, 228);background-color: rgb(166, 91, 203);word-wrap: break-word !important;text-align: justify;\"><span style=\"font-size: 14px;\">\u5173\u952e\u8d28\u91cf\u5c5e\u6027\u548c\u5173\u952e\u5de5\u827a\u53c2\u6570<\/span><\/section>\n<\/section>\n<h2 style=\"font-weight: bold;max-width: 100%;color: rgb(51, 51, 51);text-align: justify;\"><span style=\"max-width: 100%;font-size: 14px;box-sizing: border-box !important;word-wrap: break-word !important;\"><\/span><\/h2>\n<p style=\"margin-top: 1em;margin-bottom: 1em;max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);text-align: justify;\"><span style=\"font-size: 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style=\"margin-top: 1em;margin-bottom: 1em;max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);text-align: justify;\"><span style=\"font-size: 14px;\">\u4e00\u65e6\u786e\u5b9a\u4e86\u8fd9\u4e9b\u53c2\u6570\u548c\u5c5e\u6027\uff0c\u5c31\u8fdb\u884c\u98ce\u9669\u8bc4\u4f30\uff0c\u6309\u91cd\u8981\u6027\u5bf9\u6700\u6709\u5f71\u54cd\u7684\u5173\u952e\u5de5\u827a\u53c2\u6570\u548c\u6750\u6599\u5c5e\u6027\u8fdb\u884c\u7814\u7a76\uff08\u56fe2\uff09\u3002\u5173\u952e\u8d28\u91cf\u5c5e\u6027\u76f4\u63a5\u51b3\u5b9a\u4ea7\u54c1\u7684\u8d28\u91cf\uff0c\u800c\u5173\u952e\u7684\u5de5\u827a\u53c2\u6570\u548c\u6750\u6599\u5c5e\u6027\u7684\u5f71\u54cd\u5173\u952e\u8d28\u91cf\u5c5e\u6027\u95f4\u63a5\u5f71\u54cd\u4ea7\u54c1\u8d28\u91cf\u3002\u4e00\u4e9b\u5173\u952e\u8d28\u91cf\u5c5e\u6027\u53ef\u80fd\u4e0e\u53ef\u8bc6\u522b\u7684\u5173\u952e\u5de5\u827a\u53c2\u6570\u548c\u6750\u6599\u5c5e\u6027\u65e0\u5173\uff08\u56fe3\uff09\u3002<\/span><\/p>\n<p style=\"margin-top: 1em;margin-bottom: 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14px;\">\u5173\u952e\u8d28\u91cf\u5c5e\u6027\u6307\u5bfc\u5de5\u827a\u8fc7\u7a0b\u548c\u4ea7\u54c1\u5f00\u53d1\uff0c\u5e76\u5e94\u968f\u7740\u5de5\u827a\u8fc7\u7a0b\u77e5\u8bc6\u7684\u53d1\u5c55\u800c\u4e0d\u65ad\u6539\u826f\u3002\u65e9\u671f\u7684\u5de5\u827a\u53d1\u5c55\u8fc7\u7a0b\u4e2d\uff0c\u4e00\u4e2a\u57fa\u7840\u5e7f\u6cdb\u7684\u591a\u53c2\u6570\u7ec6\u80de\u5c5e\u6027\u7684\u5206\u6790\u5bf9\u4e8e\u786e\u5b9a\u5728\u4ee5\u540e\u7684\u5f00\u53d1\u9636\u6bb5\u96c6\u4e2d\u5728\u4e00\u7ec4\u66f4\u4e3a\u660e\u786e\u7684\u7684\u5173\u952e\u53c2\u6570\u662f\u6709\u7528\u7684\u3002\u503c\u5f97\u6ce8\u610f\u7684\u662f\uff0c\u8bc6\u522b\u548c\u6d4b\u91cf\u5173\u952e\u8d28\u91cf\u5c5e\u6027\u7684\u53d6\u503c\u662f\u5177\u6709\u6311\u6218\u6027\u7684\u3002\u82e5\u4e0d\u9996\u5148\u5bf9\u5173\u952e\u8d28\u91cf\u5c5e\u6027\u6709\u6240\u7406\u89e3\uff0c\u590d\u6742\u7684\u591a\u53c2\u6570\u7814\u7a76\uff08\u201c\u8bbe\u8ba1\u7a7a\u95f4\u201d\u4e0b\u9762\u8ba8\u8bba\uff09\u53ef\u80fd\u4ef7\u503c\u6709\u9650\uff0c\u8fd9\u4e9b\u7814\u7a76\u786e\u5b9a\u591a\u79cd\u53c2\u6570\u5bf9\u5173\u952e\u8d28\u91cf\u5c5e\u6027\u7684\u5f71\u54cd\u3002\u56e0\u6b64\uff0c\u65e9\u671fCTP\u7684\u53d1\u5c55\u5e94\u7740\u773c\u4e8e\u786e\u5b9a\u5173\u952e\u8d28\u91cf\u5c5e\u6027\uff0c\u968f\u7740\u8fd9\u4e9b\u57fa\u7840\u77e5\u8bc6\u7684\u589e\u957f\uff0c\u65e5\u76ca\u6210\u719f\u7684\u7ecf\u9a8c\u6216\u673a\u5236\u5b9e\u9a8c\u6a21\u578b\u53ef\u4ee5\u7528\u6765\u63a2\u7d22\u7684\u5173\u952e\u5de5\u827a\u53c2\u6570\u548c\u6750\u6599\u7279\u6027\u7684\u5f71\u54cd\u3002<\/span><\/p>\n<p style=\"margin-top: 1em;margin-bottom: 1em;max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);text-align: justify;\"><span style=\"font-size: 14px;\">\u4ea7\u54c1\u7684\u5b89\u5168\u6027\u548c\u6709\u6548\u6027\u53d7\u8bb8\u591a\u8fc7\u7a0b\u53c2\u6570\u7684\u5f71\u54cd\uff0c\u5305\u62ec\u751f\u7269\u53cd\u5e94\u5668\u7cfb\u7edf\u7684\u64cd\u4f5c\u7279\u6027\u3002\u4f8b\u5982\uff0c\u6405\u62cc\u4e0d\u4ec5\u53ef\u4ee5\u786e\u4fdd\u5747\u5300\u7684\u73af\u5883\u6761\u4ef6\u4e5f\u6539\u53d8\u526a\u5207\u654f\u611f\u7684\u7ec6\u80de\u8868\u578b\u3002\u6eb6\u6c27\u5f71\u54cdPSCs\uff0cHSPCs\u548c\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\uff0c\u5bf9\u6548\u529b\u548c\u7eaf\u5ea6\u6709\u6f5c\u5728\u5f71\u54cd\u3002\u5373\u4f7f\u8f7b\u5fae\u7684pH\u503c\u53d8\u5316\u4e5f\u4f1a\u4ea7\u751f\u91cd\u5927\u5f71\u54cd\uff0c\u5982\u679c\u4e0d\u52a0\u4ee5\u63a7\u5236\uff0c\u7ec6\u80de\u4ee3\u8c22\u4f1a\u964d\u4f4epH\u503c\u3002\u4ee3\u8c22\u526f\u4ea7\u7269\u4e5f\u4f1a\u76f4\u63a5\u5f71\u54cd\u7ed3\u679c\u3002\u4f8b\u5982\uff0c\u4e73\u9178\u7684\u79ef\u7d2f\u548cpH\u503c\u7684\u964d\u4f4e\u4e0e\u7ec6\u80de\u751f\u957f\u53d7\u6291<span style=\"font-size: 14px;max-width: 100%;line-height: 24px;box-sizing: border-box !important;word-wrap: break-word !important;\">\u5236\u548c<\/span>PSC \u8868\u578b\u635f\u5931\u6709\u5173\u3002\u5a92\u4ecb\u4ea4\u6362\u7387\u548c\u7b56\u7565\uff08\u4f8b\u5982\uff0c\u6279\uff0c\u5206\u6279\u6216\u704c\u6ce8\uff09\u53ef\u4ee5\u7528\u6765\u63a7\u5236\u5e9f\u7269\u548c\u5185\u6e90\u5206\u6ccc\u56e0\u5b50\u79ef\u7d2f\u3002<\/span><\/p>\n<p style=\"margin-top: 1em;margin-bottom: 1em;max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);text-align: justify;\"><span style=\"font-size: 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style=\"margin-top: 1em;margin-bottom: 1em;max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);text-align: justify;\"><span style=\"font-size: 14px;\">\u7ec6\u80de\u6269\u5927\u901a\u5e38\u662f\u4e00\u4e2a\u7ecf\u6d4e\u8003\u8651\uff0c\u4f46\u5982\u679c\u5b83\u5f71\u54cdCTP\u8d28\u91cf\uff0c\u53ef\u80fd\u662f\u4e00\u4e2a\u91cd\u8981\u7684\u8d28\u91cf\u5c5e\u6027.\u5bf9\u4e8e\u75c5\u4eba\u5177\u6709\u7279\u5b9a\u6027\u7684CTPs\uff0c\u7ec6\u80de\u6269\u5927\u5b9e\u73b0\u7684\u7a0b\u5ea6\u53ef\u80fd\u5f71\u54cd\u5242\u91cf\u3002\u751f\u4ea7HSPC\u548cCAR-T\u7597\u6cd5\u6765\u6e90\u4e8e\u5355\u4e00\u4f9b\u4f53\u7684\u7ec6\u80de\u9700\u8981\u8db3\u591f\u7684\u7ec6\u80de\u6269\u5f20\u4ee5\u8fbe\u5230\u9776\u5242\u91cf\u3002\u76f8\u6bd4\u4e4b\u4e0b\uff0c\u5f02\u6e90\u7684 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style=\"font-weight: bold;max-width: 100%;color: rgb(51, 51, 51);text-align: justify;\"><span style=\"max-width: 100%;font-size: 14px;box-sizing: border-box !important;word-wrap: break-word !important;\"><\/span><\/h2>\n<section class=\"\"   style=\"max-width: 100%;box-sizing: border-box;color: rgb(51, 51, 51);\">\n<section class=\"\"   placeholder=\"\u6d45\u8272\u8fb9\u6846\u6807\u9898\" style=\"margin-top: 10px;margin-bottom: 10px;padding: 10px;max-width: 100%;box-sizing: border-box;line-height: 25px;color: rgb(254, 254, 254);font-weight: bold;box-shadow: rgb(153, 153, 153) 1px 1px 2px;border-left: 25px solid rgb(208, 168, 228);border-top-color: rgb(208, 168, 228);border-right-color: rgb(208, 168, 228);border-bottom-color: rgb(208, 168, 228);background-color: rgb(166, 91, 203);word-wrap: break-word !important;text-align: justify;\"><span style=\"font-size: 14px;\">\u4ea7\u54c1\u8bbe\u8ba1\u7a7a\u95f4<\/span><\/section>\n<\/section>\n<h2 style=\"font-weight: bold;max-width: 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!important;\"><\/span><\/h2>\n<section class=\"\"   style=\"max-width: 100%;box-sizing: border-box;color: rgb(51, 51, 51);\">\n<section class=\"\"   placeholder=\"\u6d45\u8272\u8fb9\u6846\u6807\u9898\" style=\"margin-top: 10px;margin-bottom: 10px;padding: 10px;max-width: 100%;box-sizing: border-box;line-height: 25px;color: rgb(254, 254, 254);font-weight: bold;box-shadow: rgb(153, 153, 153) 1px 1px 2px;border-left: 25px solid rgb(208, 168, 228);border-top-color: rgb(208, 168, 228);border-right-color: rgb(208, 168, 228);border-bottom-color: rgb(208, 168, 228);background-color: rgb(166, 91, 203);word-wrap: break-word !important;text-align: justify;\"><span style=\"font-size: 14px;\">\u5b9e\u9a8c\u8bbe\u8ba1<\/span><\/section>\n<\/section>\n<h2 style=\"font-weight: bold;max-width: 100%;color: rgb(51, 51, 51);text-align: justify;\"><span style=\"max-width: 100%;font-size: 14px;box-sizing: border-box !important;word-wrap: break-word !important;\"><\/span><\/h2>\n<p style=\"margin-top: 1em;margin-bottom: 1em;max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);text-align: justify;\"><span style=\"font-size: 14px;\">DOE\u63cf\u8ff0\u4e86\u4e00\u7ec4\u65b9\u6cd5\uff0c\u5bf9\u4e8e\u6709\u7ec4\u7ec7\u548c\u6709\u7ed3\u6784\u7684\u79d1\u5b66\u7814\u7a76\uff0c\u4ee5\u7406\u6e05\u56e0\u7d20\u548c\u7ed3\u679c\u4e4b\u95f4\u7684\u5173\u7cfb\u3002\u751f\u7269\u53cd\u5e94\u5668\u7684\u63a7\u5236\u4e0b\uff0c\u4f7f\u5f97\u5bf9\u7ec6\u80de\u5728\u54cd\u5e94\u4e00\u7cfb\u5217\u5173\u952e\u5de5\u827a\u53c2\u6570\u7684\u53d8\u5316\u540e\u7684\u884c\u4e3a\u505a\u51fa\u7cfb\u7edf\u8bc4\u4ef7\u6210\u4e3a\u53ef\u80fd\uff0c\u4ece\u800c\u8bc6\u522b\u6700\u4f18\u64cd\u4f5c\u6761\u4ef6\u548c\u9610\u660e\u4ea7\u54c1\u5de5\u827a\u7684\u8bbe\u8ba1\u7a7a\u95f4\u3002\u5df2\u6709\u7684\u65b9\u6cd5\u53ef\u4ee5\u5728\u7edf\u8ba1\u5b66\u4e0a\u6709\u610f\u4e49\u7684\u63a2\u7d22\u548c\u591a\u53c2\u6570\u8fc7\u7a0b\u7684\u754c\u5b9a\u65b9\u6cd5\u6d89\u53ca\u5230\u4e00\u7cfb\u5217\u7684\u6d4b\u8bd5\u6765\u786e\u5b9a\u8f93\u5165\u53d8\u91cf\uff08\u5355\u72ec\u6216\u7ec4\u5408\uff09\u5bf9\u7ed3\u679c\u7684\u5f71\u54cd\u3002DOE\u53ef\u4ee5\u7528\u6765\u5f00\u53d1\u7531\u4f20\u7edf\u65b9\u6cd5\u9010\u6b65\u4f18\u5316\u770b\u8d77\u6765\u9ad8\u4e0d\u53ef\u6500\u9ad8\u5ea6\u7684\u8fc7\u7a0b\uff0c\u4ece\u800c\u589e\u52a0\u8fc7\u7a0b\u7684\u5065\u5f3a\u6027\u548c\u6210\u672c\u6548\u7387\uff0c\u6b64\u5916\u5b83\u8fd8\u53ef\u4ee5\u7528\u6765\u8fdb\u884c\u7efc\u5408\u6210\u672c\u5206\u6790\u3002\u591a\u53c2\u6570\u7814\u7a76\u5c06\u53d7\u76ca\u4e8e\u4f7f\u7528\u65b0\u7684\u5c0f\u89c4\u6a21\u751f\u7269\u53cd\u5e94\u5668\u7cfb\u7edf\u6765\u5f00\u53d1\u5173\u952e\u5de5\u827a\u53c2\u6570\u7684\u54cd\u5e94\u9762\uff08\u65b9\u68462\uff09\u3002<\/span><\/p>\n<p style=\"text-align:center;\"><img loading=\"lazy\" class=\"\"     height=\"409\" style=\"box-sizing: border-box !important;word-wrap: break-word !important;width: 440px !important;visibility: visible !important;\" width=\"440\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/07\/beepress4-1532684843.jpg\" alt=\"\u7ec6\u80de\u6cbb\u7597\u5de5\u827a\u4e2d\u7684\u8d28\u91cf\u6e90\u4e8e\u8bbe\u8ba1\" title=\"\u7ec6\u80de\u6cbb\u7597\u5de5\u827a\u4e2d\u7684\u8d28\u91cf\u6e90\u4e8e\u8bbe\u8ba1\"  \/><\/p>\n<p style=\"margin-top: 1em;margin-bottom: 1em;max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);text-align: justify;\"><span style=\"font-size: 14px;\">\u57fa\u4e8eDOE\u7684\u76f8\u4e92\u4f5c\u7528\u7684\u4e24\u4e2a\u5173\u952e\u5de5\u827a\u53c2\u6570\u7684\u5f71\u54cd\u7684\u8c03\u67e5\uff08\u64ad\u79cd\u5bc6\u5ea6\u3001\u6405\u62cc\u901f\u7387\uff09\u5bf9PSC\u57f9\u517b\u786e\u5b9a\u4e86\u5de5\u827a\u4f18\u5316\uff0c\u9010\u6b65\u5b9e\u9a8c\u53ef\u80fd\u4f1a\u9519\u8fc7\u3002\u5173\u4e8e\u64ad\u79cd\u5bc6\u5ea6\u7684\u76f8\u4f3c\u7814\u7a76\uff0c\u57f9\u517b\u57fa\u4f53\u79ef\u548c\u8865\u6599\u65f6\u95f4\u4f7f\u7528\u54cd\u5e94\u9762\u5206\u6790\u6cd5\u4ee5\u786e\u5b9a\u7ec6\u80de\u5206\u88c2\u4e4b\u540e\u7ec6\u80de\u6700\u4f73\u4ea7\u91cf\u7684\u6761\u4ef6\u3002\u5728\u5bf9HSPC \u7684\u7814\u7a76\u4e2d\uff0c\u6211\u4eec\u65e9\u671f\u7814\u7a76\u7ec6\u80de\u6269\u5927\u6240\u5fc5\u9700\u7684\u7ec6\u80de\u56e0\u5b50\uff0c\u591a\u4e2a\u7814\u7a76\u91c7\u7528\u4e86DOE\u65b9\u6cd5\u7684\u63a2\u7d22\u548c\u4f18\u5316\u7ec6\u80de\u57f9\u517b\u3002\u4ece\u9020\u8840\u5e72\u7ec6\u80de\u4ea7\u751f\u4e2d\u6027\u7c92\u7ec6\u80de\uff0c\u6709\u7814\u7a76\u53d1\u73b0\u6b64\u8fc7\u7a0b\u53d7\u56db\u79cd\u7ec6\u80de\u56e0\u5b50\u7684\u4ea4\u4e92\u4f5c\u7528\u6240\u63a7\u5236\uff0c\u8fd9\u4e00\u8fc7\u7a0b\u5982\u679c\u6ca1\u6709DOE\u65b9\u6cd5\u4e0d\u53ef\u80fd\u88ab\u53d1\u73b0\uff0c\u4f7f\u7528\u7ec6\u80de\u56e0\u5b50\u7684\u7b80\u5316\u6a21\u578b\u4e5f\u4e0d\u53ef\u80fd\u53d1\u73b0\u3002\u5728\u5bf9MSC\u7684\u7814\u7a76\u4e2d\uff0c\u521d\u6b65\u8bbe\u8ba1\u7a7a\u95f4\u5df2\u7ecf\u786e\u5b9a\u4e86\u4e0d\u540c\u7684\u5fae\u8f7d\u4f53\uff0c\u7ec6\u80de\u63a5\u79cd\u5bc6\u5ea6\uff0c\u53f6\u8f6e\u51e0\u4f55\u53c2\u6570\u5bf9\u6700\u7ec8\u7ec6\u80de\u6269\u5927\u7684\u5f71\u54cd\u3002<\/span><\/p>\n<p style=\"margin-top: 1em;margin-bottom: 1em;max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);text-align: justify;\"><span style=\"font-size: 14px;\">DOE\u5fc5\u987b\u5c06\u5173\u952e\u8fc7\u7a0b\u53c2\u6570\u4e0d\u4ec5\u4e0e\u7ec6\u80de\u6269\u5927\u76f8\u5173\u7684\u5173\u952e\u8d28\u91cf\u5c5e\u6027\u8054\u7cfb\u8d77\u6765\uff0c\u800c\u4e14\u8fd8\u8981\u4e0e\u8eab\u4efd\u3001\u6548\u529b\u548c\u7eaf\u5ea6\u5c5e\u6027\u76f8\u5173\u8054\u3002\u6211\u4eec\u5f3a\u8c03\u7684\u662f\u591a\u53c2\u6570\u7684\u8c03\u67e5\u5e94\u8be5\u53ea\u9488\u5bf9\u6700\u91cd\u8981\u7684\u5173\u952e\u8d28\u91cf\u5c5e\u6027\uff1b\u8fc7\u5ea6\u5206\u6790\u98ce\u9669\u8bc6\u522b\u65e0\u5173\u7684\u7279\u6027\uff0c\u53ef\u80fd\u5bfc\u81f4\u5bf9\u751f\u4ea7\u8fc7\u7a0b\u4e2d\u7684\u72b6\u6001\u4fe1\u606f\u7684\u8bef\u5bfc\u3002\u968f\u7740\u8fc7\u7a0b\u77e5\u8bc6\u7684\u53d1\u5c55\uff0c\u5bf9\u5173\u952e\u8d28\u91cf\u5c5e\u6027\u548c\u5173\u952e\u8fc7\u7a0b\u53c2\u6570\u7684\u53cd\u590d\u8bc4\u4f30\u6709\u52a9\u4e8e\u6d88\u9664\u4e0d\u76f8\u5173\u53c2\u6570\u7684\u7814\u7a76\u3002<\/span><\/p>\n<h2 style=\"font-weight: bold;max-width: 100%;color: rgb(51, 51, 51);text-align: justify;\"><span style=\"max-width: 100%;font-size: 14px;box-sizing: border-box !important;word-wrap: break-word !important;\"><\/span><\/h2>\n<section class=\"\"   style=\"max-width: 100%;box-sizing: border-box;color: rgb(51, 51, 51);\">\n<section class=\"\"   placeholder=\"\u6d45\u8272\u8fb9\u6846\u6807\u9898\" style=\"margin-top: 10px;margin-bottom: 10px;padding: 10px;max-width: 100%;box-sizing: border-box;line-height: 25px;color: rgb(254, 254, 254);font-weight: bold;box-shadow: rgb(153, 153, 153) 1px 1px 2px;border-left: 25px solid rgb(208, 168, 228);border-top-color: rgb(208, 168, 228);border-right-color: rgb(208, 168, 228);border-bottom-color: rgb(208, 168, 228);background-color: rgb(166, 91, 203);word-wrap: break-word !important;text-align: justify;\"><span style=\"font-size: 14px;\">\u7cfb\u7edf\u5efa\u6a21<\/span><\/section>\n<\/section>\n<h2 style=\"font-weight: bold;max-width: 100%;color: rgb(51, 51, 51);\"><\/h2>\n<p style=\"margin-top: 1em;margin-bottom: 1em;max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);text-align: justify;\"><span style=\"font-size: 14px;\">\u9274\u4e8e\u7ec6\u80de\u4e0e\u73af\u5883\u4e4b\u95f4\u76f8\u4e92\u4f5c\u7528\u7684\u590d\u6742\u6027\uff0c\u7cfb\u7edf\u5efa\u6a21\u5c06\u4f7f\u5f97\u5f00\u53d1\u8bbe\u8ba1\u7a7a\u95f4\u83b7\u76ca\u5de8\u5927\u3002\u5927\u7ec4\u5b66\u6570\u636e\u96c6\u63d0\u4f9b\u4e86\u6784\u5efa\u51cf\u5c11\u53c2\u6570\u7684\u673a\u5236\u6a21\u578b\u7684\u51fa\u53d1\u70b9\uff0c\u8fd9\u4e00\u6a21\u578b\u5c06\u5173\u952e\u5de5\u827a\u53c2\u6570\u4e0e\u5173\u952e\u8d28\u91cf\u5c5e\u6027\u8054\u7cfb\u8d77\u6765\uff08\u56fe3\uff09\u3002\u5c3d\u7ba1\u8fc4\u4eca\u4e3a\u6b62\u8fd8\u6ca1\u6709\u4ea7\u751f\u8fc7\u8fd9\u6837\u7684\u6a21\u578b\uff0c\u4f46\u5404\u79cd\u5404\u6837\u7684\u6a21\u578b\u6280\u672f\u5df2\u88ab\u7528\u4e8e\u6574\u5408\u7ec6\u80de\u548c\u751f\u7269\u4fe1\u53f7\uff0c\u4ee5\u9884\u6d4b\u4e0eCTP\u751f\u4ea7\u76f8\u5173\u7684\u5173\u952e\u8d28\u91cf\u5c5e\u6027\u3002\u5e72\u7ec6\u80de\u8fc7\u6e21\u72b6\u6001\u7684\u5212\u5206\u6a21\u578b\u6307\u5bfc\u5fae\u73af\u5883\u8c03\u63a7\u548c\u57f9\u517b\u8865\u6599\u7b56\u7565\u3002\u57fa\u4e8e\u7ec4\u5b66\u6570\u636e\u7684\u4ee3\u8c22\u9014\u5f84\u5206\u6790\u548c\u91cd\u5efa\u5df2\u88ab\u5e7f\u6cdb\u5e94\u7528\u4e8e\u4f18\u5316\u751f\u7269\u5236\u836f\u751f\u4ea7\u5e76\u9002\u7528\u4e8eCTP\u751f\u4ea7\u3002\u8fd9\u4e9b\u5206\u6790\uff0c\u63cf\u8ff0\u4e86\u7279\u5b9a\u6c28\u57fa\u9178\u5bf9\u4e8ePSC \u57f9\u517b\u7684\u5173\u952e\u6027\uff0c\u800c\u4ee3\u8c22\u901a\u91cf\u5206\u6790\u5df2\u88ab\u7528\u4e8e\u63cf\u8ff0\u5728\u4e0d\u540c\u7684\u6c27\u6c34\u5e73PSCs \u6307\u6570\u751f\u957f\u65f6\u4ee3\u8c22\u901a\u8def\u7684\u6d3b\u6027\uff0c\u4ee5\u9884\u77e5\u57f9\u517b\u57fa\u7684\u914d\u65b9\u3002\u6700\u8fd1\uff0cPSCs \u6765\u6e90\u7684\u5fc3\u808c\u7ec6\u80de\u4e0d\u540c\u7684\u4e73\u9178\u4ee3\u8c22\u6a21\u578b\u5df2\u88ab\u5229\u7528\u6765\u5b9e\u73b0\u9ad8\u7eaf\u5ea6\u7684\u5fc3\u808c\u7ec6\u80de\uff0c\u8868\u660e\u57fa\u4e8e\u4ee3\u8c22\u5efa\u6a21\u6765\u4f18\u5316CTP\u751f\u4ea7\u662f\u53ef\u884c\u7684\u3002<\/span><\/p>\n<p style=\"margin-top: 1em;margin-bottom: 1em;max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);text-align: justify;\"><span style=\"font-size: 14px;\">\u968f\u7740\u4ea7\u54c1\u7684\u53d1\u5c55\uff0c\u5927\u91cf\u7684\u6709\u4ef7\u503c\u7684\u6570\u636e\u79ef\u7d2f\u8d77\u6765\u3002\u5c06\u8fd9\u4e9b\u6570\u636e\u5173\u8054\u5230\u5173\u952e\u8d28\u91cf\u5c5e\u6027\uff0c\u4ee5\u5efa\u7acb\u8d77\u7f51\u7edc\u6a21\u578b\u8fbe\u5230\u9884\u6d4b\u76ee\u7684\u6280\u672f\u5f97\u4ee5\u5f00\u53d1\u3002\u4f8b\u5982\uff0c\u7edf\u8ba1\u5de5\u5177\u5982\u591a\u5143\u5206\u6790\u53ef\u4ee5\u8bc6\u522b\u57fa\u56e0\u7684\u5b50\u96c6\uff08\u6216\u5176\u4ed6\u5143\u7d20\uff09\u5728\u7ec4\u5b66\u6570\u636e\uff0c\u8fd9\u4e9b\u6570\u636e\u4e0e\u6240\u671f\u5f85\u53cd\u5e94\u6709\u5173\u3002\u8fd9\u79cd\u65b9\u6cd5\u786e\u5b9a\u4e86\u591a\u79cd\u6837\u54c1\u4e2d\u7684\u8d77\u59cb\u548c\u6700\u7ec8\u7684HSPC\u7684\u79cd\u7fa4\u6784\u6210\uff0c\u8fd9\u4e00\u79cd\u7fa4\u6784\u6210\u662f\u4e00\u4e2a\u5173\u952e\u7684\u5de5\u827a\u53c2\u6570\uff0c\u53ef\u88ab\u7528\u4e8e\u4f5c\u4e3a\u5176\u4ed6\u75c5\u4eba\u7279\u5b9a\u6cbb\u7597\u7684\u8d77\u59cb\u6750\u6599\u53d8\u5f02\u6027\u79cd\u7fa4\u6784\u6210\u7684\u53c2\u8003\u3002\u57fa\u4e8e\u6269\u5c55\u6a21\u578b\u4ee5\u8bc6\u522b\u5173\u952e\u8fc7\u7a0b\u53c2\u6570\uff0c\u57fa\u4e8e\u57fa\u56e0\u8868\u8fbe\u6570\u636e\u96c6\uff0c\u6a21\u578b\u8bbe\u8ba1\u7a7a\u95f4\u7684\u53d1\u5c55\uff0c\u9700\u8981\u4e0e\u786e\u5b9a\u5173\u952e\u5de5\u827a\u53c2\u6570\u76f8\u5173\u7684\u57fa\u56e0\u8c03\u63a7\u7f51\u7edc\u7684\u9884\u6d4b\u548c\u9a8c\u8bc1\u3002\u6700\u8fd1\u5173\u4e8e\u8f93\u5165\u56e0\u5b50\u4e0e\u53d8\u5316\u7684\u7ec6\u80de\u72b6\u6001\u7684\u76f8\u5173\u6027\u8ba1\u7b97\u8868\u660e\uff0c\u57fa\u56e0\u8c03\u63a7\u7f51\u7edc\u53ef\u4ee5\u94fe\u63a5\u5173\u952e\u5de5\u827a\u53c2\u6570\u548c\u5173\u952e\u8d28\u91cf\u5c5e\u6027\u3002CTP\u9886\u57df\u7684\u6709\u4ef7\u503c\u7684\u4e0b\u4e00\u6b65\u662f\u4f7f\u7528\u5efa\u6a21\u6280\u672f\u5c06\u8868\u578b\u4e0e\u6548\u529b\u8054\u7cfb\u8d77\u6765\u3002<\/span><\/p>\n<h2 style=\"font-weight: bold;max-width: 100%;color: rgb(51, 51, 51);text-align: justify;\"><span style=\"max-width: 100%;font-size: 14px;box-sizing: border-box !important;word-wrap: break-word !important;\"><\/span><\/h2>\n<section class=\"\"   style=\"max-width: 100%;box-sizing: border-box;color: rgb(51, 51, 51);\">\n<section class=\"\"   placeholder=\"\u6d45\u8272\u8fb9\u6846\u6807\u9898\" style=\"margin-top: 10px;margin-bottom: 10px;padding: 10px;max-width: 100%;box-sizing: border-box;line-height: 25px;color: rgb(254, 254, 254);font-weight: bold;box-shadow: rgb(153, 153, 153) 1px 1px 2px;border-left: 25px solid rgb(208, 168, 228);border-top-color: rgb(208, 168, 228);border-right-color: rgb(208, 168, 228);border-bottom-color: rgb(208, 168, 228);background-color: rgb(166, 91, 203);word-wrap: break-word !important;text-align: justify;\"><span style=\"font-size: 14px;\">\u63a7\u5236\u7b56\u7565<\/span><\/section>\n<\/section>\n<h2 style=\"font-weight: bold;max-width: 100%;color: rgb(51, 51, 51);text-align: justify;\"><span style=\"max-width: 100%;font-size: 14px;box-sizing: border-box !important;word-wrap: break-word !important;\"><\/span><\/h2>\n<p style=\"margin-top: 1em;margin-bottom: 1em;max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);text-align: justify;\"><span style=\"font-size: 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style=\"font-weight: bold;max-width: 100%;color: rgb(51, 51, 51);text-align: justify;\"><span style=\"max-width: 100%;font-size: 14px;box-sizing: border-box !important;word-wrap: break-word !important;\"><\/span><\/h2>\n<section class=\"\"   style=\"max-width: 100%;box-sizing: border-box;color: rgb(51, 51, 51);\">\n<section class=\"\"   placeholder=\"\u6d45\u8272\u8fb9\u6846\u6807\u9898\" style=\"margin-top: 10px;margin-bottom: 10px;padding: 10px;max-width: 100%;box-sizing: border-box;line-height: 25px;color: rgb(254, 254, 254);font-weight: bold;box-shadow: rgb(153, 153, 153) 1px 1px 2px;border-left: 25px solid rgb(208, 168, 228);border-top-color: rgb(208, 168, 228);border-right-color: rgb(208, 168, 228);border-bottom-color: rgb(208, 168, 228);background-color: rgb(166, 91, 203);word-wrap: break-word !important;text-align: justify;\"><span style=\"font-size: 14px;\">QbD\u7684\u672a\u6765\u5e94\u7528<\/span><\/section>\n<\/section>\n<h2 style=\"font-weight: bold;max-width: 100%;color: 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14px;\">\u5c3d\u7ba1CTPs\u751f\u4ea7\u7684\u4ea7\u4e1a\u5316\u9762\u4e34\u8bf8\u591a\u6311\u6218\uff0c\u5176\u524d\u666f\u5341\u5206\u4e50\u89c2\u3002\u51e0\u5341\u5e74\u7ec6\u80de\u57f9\u517b\u4ea7\u4e1a\u5316\u5de5\u827a\u8bbe\u8ba1\u7684\u7ecf\u9a8c\uff0c\u63d0\u4f9b\u4e86\u5728\u751f\u7269\u53cd\u5e94\u5668\u7684\u653e\u5927\u548c\u5f3a\u5316\uff0c\u7ec6\u80de\u4ee3\u8c22\uff0c\u57f9\u517b\u57fa\u8bbe\u8ba1\uff0c\u8865\u6599\u7b56\u7565\u4f18\u5316\u548c\u5de5\u827a\u8fc7\u7a0b\u63a7\u5236\u65b9\u9762\u7684\u5de5\u4e1a\u5316\u57fa\u7840\u3002\u6211\u4eec\u5bf9\u7ec6\u80de\u4e0e\u73af\u5883\u76f8\u4e92\u4f5c\u7528\u7684\u7406\u89e3\u8ba4\u8bc6\u6b63\u5728\u63d0\u9ad8\uff0c\u80fd\u591f\u63a7\u5236\u7ec6\u80de\u73af\u5883\u7684\u751f\u7269\u53cd\u5e94\u5668\u7cfb\u7edf\uff0c\u6b63\u5728\u751f\u6210\u8d8a\u6765\u8d8a\u96c6\u4e2d\u4e8e\u5206\u5b50\u548c\u7ec6\u80de\u4fe1\u606f\u7684\u6570\u636e\u96c6\u3002\u4e0e\u6b64\u540c\u65f6\uff0c\u6211\u4eec\u5bf9\u7ec6\u80de\u72b6\u6001\u7684\u5206\u5b50\u57fa\u7840\u7684\u8ba4\u8bc6\uff0c\u5305\u62ec\u7c98\u9644\u4f9d\u8d56\uff0c\u4ee3\u8c22\u7f51\u7edc\u72b6\u6001\uff0c\u96c6\u843d\u5f62\u6210\u548c\u589e\u6b96\u7684\u63a7\u5236\uff0c\u6b63\u5728\u4e0d\u65ad\u63d0\u9ad8\u3002\u867d\u7136\u6211\u4eec\u5728\u6b64\u96c6\u4e2d\u8ba8\u8bba\u7684\u662f\u4e0a\u6e38\u751f\u4ea7\u5de5\u827a\u8fc7\u7a0b\uff0cQbD\u5bf9\u4e0b\u6e38\u64cd\u4f5c\u540c\u6837\u9002\u7528\u3002\u540c\u6837\uff0c\u5de5\u827a\u8bbe\u8ba1\u53ea\u662f\u4ea7\u54c1\u751f\u547d\u5468\u671f\u7684\u4e00\u90e8\u5206\uff0c\u5229\u7528\u8fd9\u91cc\u63cf\u8ff0\u7684QbD\u5de5\u5177\u4e3aCTP\u751f\u547d\u5468\u671f\u521b\u9020\u4e86\u7075\u6d3b\u53ef\u53d8\u53c8\u7ecf\u5f97\u8d77\u68c0\u9a8c\u7684\u5de5\u827a\u3002<\/span><\/p>\n<p style=\"margin-top: 1em;margin-bottom: 1em;max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);text-align: justify;\"><span style=\"font-size: 14px;\">CTPs\u7684\u672a\u6765\u53d6\u51b3\u4e8e\u7ec6\u80de\u751f\u4ea7\u4f4e\u6210\u672c\u6280\u672f\u7684\u53d1\u5c55\u3002\u9274\u4e8eCTPs\u56fa\u6709\u7684\u590d\u6742\u6027\u548c\u5b83\u7684\u751f\u4ea7\u5de5\u827a\uff0c\u5c06\u4eca\u5929\u8bd5\u9a8c\u4e2dCTPs\u8f6c\u6362\u6210\u5e7f\u6cdb\u4f7f\u7528\u7684\u836f\u7269\uff0cQbD\u65b9\u6cd5\u662f\u5fc5\u4e0d\u53ef\u5c11\u7684\u3002<\/span><\/p>\n<p style=\"margin-top: 1em;margin-bottom: 1em;max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);text-align: justify;\"><span style=\"max-width: 100%;white-space: pre-wrap;font-size: 14px;box-sizing: border-box !important;word-wrap: break-word !important;\">\u53c2\u8003\u6587\u732e\uff1a<\/span><\/p>\n<p style=\"margin-top: 1em;margin-bottom: 1em;max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);text-align: justify;\"><span style=\"max-width: 100%;font-size: 14px;box-sizing: border-box !important;word-wrap: break-word !important;\">Lipsitz YY, Timmins NE, Zandstra PW.Quality cell therapy manufacturing by design.Nat Biotechnol. 2016 Apr;34(4):393-400.<\/span><\/p>\n<p style=\"margin-top: 1em;margin-bottom: 1em;max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);text-align: justify;\"><span style=\"max-width: 100%;font-size: 14px;box-sizing: border-box !important;word-wrap: break-word !important;\"><strong style=\"color: rgb(51, 51, 51);white-space: normal;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"><\/strong><\/span><\/p>\n<blockquote class='keep-source'>\n<p>\u59cb\u53d1\u4e8e\u5fae\u4fe1\u516c\u4f17\u53f7\uff1a                         \u836f\u65f6\u7a7a                      <\/p>\n<\/blockquote>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>\u5c06\u6d3b\u4f53\u7ec6\u80de\u4f5c\u4e3a\u6cbb\u7597\u836f\u7269\u8fdb\u884c\u79fb\u690d\u7684\u6cbb\u7597\u65b9\u6cd5\u4e3a\u8bb8\u591a\u6025\u6027\u75c5\u548c\u6162\u6027\u75c5\u63d0\u4f9b\u4e86\u65b0\u578b\u7684\u6cbb\u7597\u9009\u62e9\u3002\u7136\u800c\u7ec6\u80de\u7684\u751f\u7269\u590d\u6742\u6027\u5374\u9650\u5236\u4e86 [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":10424,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[2],"tags":[],"_links":{"self":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/10423"}],"collection":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/comments?post=10423"}],"version-history":[{"count":1,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/10423\/revisions"}],"predecessor-version":[{"id":10432,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/10423\/revisions\/10432"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/media\/10424"}],"wp:attachment":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/media?parent=10423"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/categories?post=10423"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/tags?post=10423"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}