{"id":105819,"date":"2019-03-25T00:00:50","date_gmt":"2019-05-17T09:06:22","guid":{"rendered":"http:\/\/www.05921.net\/index.php\/105819\/"},"modified":"2019-05-17T17:06:24","modified_gmt":"2019-05-17T09:06:24","slug":"9d3f473f9c","status":"publish","type":"post","link":"https:\/\/www.05921.net\/index.php\/105819\/","title":{"rendered":"\u7a81\u7834\uff01\u79d1\u5b66\u5bb6\u9274\u522b\u51fa\u764c\u75c7\u514d\u75ab\u7597\u6cd5\u7684\u6f5c\u5728\u65b0\u578b\u9776\u70b9\uff1aGARP"},"content":{"rendered":"<div class=\"bpp-post-content\">\n<p style=\"max-width: 100%;min-height: 1em;letter-spacing: 0.544px;white-space: normal;background-color: rgb(255, 255, 255);text-align: center;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><br  \/><\/p>\n<section style=\"margin: auto;padding-right: 30px;padding-left: 30px;max-width: 100%;box-sizing: border-box;letter-spacing: 0.544px;white-space: normal;background-color: rgb(255, 255, 255);-webkit-tap-highlight-color: rgba(255, 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10px;margin-bottom: 10px;max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\">\n<section style=\"padding-bottom: 2px;max-width: 100%;box-sizing: border-box;border-bottom: 1px dashed rgb(207, 225, 209);overflow-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box;border-bottom: 2px solid rgb(207, 225, 209);color: rgb(127, 127, 127);line-height: 2;letter-spacing: 2px;overflow-wrap: break-word !important;\">\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 16px;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u8fd1\u65e5\uff0c\u4e00\u9879\u520a\u767b\u5728\u56fd\u9645\u6742\u5fd7Cancer 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break-word !important;\"  \/><\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"max-width: 100%;letter-spacing: 0.544px;white-space: normal;background-color: rgb(255, 255, 255);box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<p style=\"max-width: 100%;min-height: 1em;line-height: 2em;letter-spacing: 1px;text-indent: 2em;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 16px;box-sizing: border-box !important;overflow-wrap: break-word 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!important;\">\u8fd1\u65e5\uff0c\u4e00\u9879\u520a\u767b\u5728\u56fd\u9645\u6742\u5fd7Cancer Research\u4e0a\u7684\u7814\u7a76\u62a5\u544a\u4e2d\uff0c\u6765\u81ea\u5357\u5361\u7f57\u6765\u7eb3\u533b\u79d1\u5927\u5b66\u7684\u79d1\u5b66\u5bb6\u4eec\u901a\u8fc7\u7814\u7a76\u53d1\u73b0\u4e86\u4e00\u79cd<strong style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u6f5c\u5728\u7684\u9488\u5bf9\u7ed3\u76f4\u80a0\u764c\u514d\u75ab\u6cbb\u7597\u7684\u65b0\u9776\u70b9<\/strong>\u3002<\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;line-height: 2em;letter-spacing: 1px;text-indent: 2em;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><br  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;text-align: center;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><img class=\"\"       style=\"box-sizing: border-box !important;overflow-wrap: break-word !important;width: 100%;visibility: visible !important;height: auto;\"    src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2019\/05\/5-1558083983.jpeg\" alt=\"\u7a81\u7834\uff01\u79d1\u5b66\u5bb6\u9274\u522b\u51fa\u764c\u75c7\u514d\u75ab\u7597\u6cd5\u7684\u6f5c\u5728\u65b0\u578b\u9776\u70b9\uff1aGARP\" title=\"\u7a81\u7834\uff01\u79d1\u5b66\u5bb6\u9274\u522b\u51fa\u764c\u75c7\u514d\u75ab\u7597\u6cd5\u7684\u6f5c\u5728\u65b0\u578b\u9776\u70b9\uff1aGARP\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;line-height: 2em;letter-spacing: 1px;text-indent: 2em;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><br  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;line-height: 2em;letter-spacing: 1px;text-indent: 2em;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 16px;box-sizing: border-box !important;overflow-wrap: break-word 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1em;line-height: 2em;letter-spacing: 1px;text-indent: 2em;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;line-height: 2em;letter-spacing: 1px;text-indent: 2em;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 16px;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u7814\u7a76\u4eba\u5458\u975e\u5e38\u611f\u5174\u8da3\u7814\u7a76Tregs\u7ec6\u80de\u5728\u8010\u53d7\u6027\u548c\u764c\u75c7\u7b49\u591a\u79cd\u75be\u75c5\u4e2d\u662f\u5982\u4f55\u88ab\u8c03\u8282\u7684\uff0c\u4ed6\u4eec\u5bf9\u4e34\u5e8a\u524d\u6a21\u578b\u8fdb\u884c\u7814\u7a76\u53d1\u73b0\uff0c\u5e72\u6270GARP\u5c31\u80fd\u591f\u964d\u4f4e\u764c\u75c7\u7684\u8010\u53d7\u6027\uff0c\u6291\u5236\u7ed3\u80a0\u764c\u7684\u53d1\u5c55\uff0c\u5e76\u6291\u5236Treg\u7ec6\u80de\u8fc1\u79fb\u5230\u80a0\u9053\u7ec4\u7ec7\u4e2d\u3002Li\u8bf4\u9053\uff0c\u6211\u4eec\u53d1\u73b0<strong style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u8c03\u8282\u6027T\u7ec6\u80de\u8868\u9762\u7684GARP\u5bf9\u4e8e\u514d\u75ab\u8010\u53d7\u6027\u975e\u5e38\u91cd\u8981\uff0c\u5176\u4f3c\u4e4e\u8fd8\u4e0e\u80a0\u9053\u764c\u75c7\u7684\u514d\u75ab\u9003\u9038\u673a\u5236\u6709\u5173<\/strong>\u3002<\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;line-height: 2em;letter-spacing: 1px;text-indent: 2em;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;line-height: 2em;letter-spacing: 1px;text-indent: 2em;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 16px;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u5f53\u7814\u7a76\u8005\u5bf9\u7ed3\u80a0\u708e\u5c0f\u9f20\u6a21\u578b\u8fdb\u884c\u7814\u7a76\u540e\u53d1\u73b0\uff0cTreg\u7ec6\u80de\u8868\u9762GARP\u7684\u9057\u4f20\u6027\u5254\u9664\u6216\u4f1a\u6291\u5236\u514d\u75ab\u7cfb\u7edf\u5728\u80a0\u9053\u5185\u4fdd\u6301\u6700\u4f73\u7684\u8010\u53d7\u6027\uff0c\u82e5\u6ca1\u6709GARP\uff0cTreg\u7ec6\u80de\u4fbf\u4e0d\u4f1a\u518d\u6709\u6548\u6291\u5236\u673a\u4f53\u7684\u514d\u75ab\u7cfb\u7edf\u4e86\uff0c\u6b64\u5916\uff0c\u76f8\u6bd4GARP\u5b8c\u6574\u7684\u5c0f\u9f20\u6a21\u578b\u76f8\u6bd4\uff0c\u5254\u9664\u7ed3\u80a0\u764c\u5c0f\u9f20\u6a21\u578b\u4e2dTreg\u7ec6\u80de\u4e0a\u7684GARP\u540e\uff0c\u5c0f\u9f20\u673a\u4f53\u4e2d\u7684\u80bf\u7624\u5c31\u4f1a\u51cf\u5c11\u4e00\u534a\u3002<\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;line-height: 2em;letter-spacing: 1px;text-indent: 2em;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><br  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;line-height: 2em;letter-spacing: 1px;text-align: left;text-indent: 0em;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 16px;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><img class=\"\"       style=\"text-align: center;box-sizing: border-box !important;overflow-wrap: break-word !important;width: 100%;visibility: visible !important;height: auto;\"    src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2019\/05\/1-1558083983.jpg\" alt=\"\u7a81\u7834\uff01\u79d1\u5b66\u5bb6\u9274\u522b\u51fa\u764c\u75c7\u514d\u75ab\u7597\u6cd5\u7684\u6f5c\u5728\u65b0\u578b\u9776\u70b9\uff1aGARP\" title=\"\u7a81\u7834\uff01\u79d1\u5b66\u5bb6\u9274\u522b\u51fa\u764c\u75c7\u514d\u75ab\u7597\u6cd5\u7684\u6f5c\u5728\u65b0\u578b\u9776\u70b9\uff1aGARP\"  \/><\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;line-height: 2em;letter-spacing: 1px;text-indent: 2em;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 16px;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u5728\u4e34\u5e8a\u524d\u764c\u75c7\u6a21\u578b\u4e2d\uff0cTreg\u7ec6\u80de\u4e0a\u6ca1\u6709GARP\u7684\u5c0f\u9f20\u9884\u540e\u8868\u73b0\u826f\u597d\uff0c\u800c\u4e14\u4f1a\u6709\u66f4\u591aT\u7ec6\u80de\u6d78\u6da6\u5230\u80bf\u7624\u7ec4\u7ec7\u4e2d\u3002\u66f4\u6709\u610f\u601d\u7684\u662f\uff0c\u8fd9\u4f3c\u4e4e\u53ea\u662f\u80a0\u9053\u5185\u7684\u60c5\u51b5\u3002\u5f53\u7814\u7a76\u8005\u8bf1\u5bfc\u5c0f\u9f20\u673a\u4f53\u5176\u5b83\u90e8\u4f4d\u51fa\u73b0\u764c\u75c7\uff08\u6bd4\u5982\u76ae\u80a4\uff09\u65f6\uff0cTreg\u7ec6\u80de\u4e0a\u643a\u5e26GARP\u4e0e\u5426\u4f3c\u4e4e\u5e76\u6ca1\u6709\u5dee\u5f02\u8868\u73b0\u3002<\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;text-align: center;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;line-height: 2em;letter-spacing: 1px;text-indent: 2em;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 16px;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u53c2\u4e0eTreg\u7ec6\u80de\u8c03\u8282\u673a\u5236\u7684\u53e6\u4e00\u4e2a\u5206\u5b50\u5c31\u662fTGF-\u03b2\uff0c\u5176\u80fd\u88ab\u7ec6\u80de\u6240\u91ca\u653e\u5e76\u8c03\u8282\u514d\u75ab\u7cfb\u7edf\u7684\u4e0d\u540c\u90e8\u5206\uff0cGARP\u4e3b\u8981\u53c2\u4e0e\u4e86TGF-\u03b2\u7684\u6fc0\u6d3b\uff0c\u7814\u7a76\u8005\u8868\u793a\uff0cGARP\u548cTGF-\u03b2\u80fd\u591f\u901a\u529b\u5408\u4f5c\u6765\u8c03\u8282Treg\u7ec6\u80de\u5411\u80a0\u9053\u4e2d\u8fc1\u79fb\u3002\u5982\u679c\u7814\u7a76\u8005\u9610\u660e\u4e86\u7ed3\u80a0\u764c\u7ec6\u80de\u589e\u52a0Treg\u7ec6\u80de\u8fc1\u79fb\u5230\u80a0\u9053\u4e2d\u7684\u5206\u5b50\u673a\u5236\uff0c\u90a3\u4e48\u5c31\u6709\u671b\u963b\u65ad\u8fd9\u79cd\u5f52\u5de2\u4fe1\u53f7\uff08homing signal\uff09\uff0c\u4ece\u800c\u4fc3\u8fdb\u673a\u4f53\u514d\u75ab\u7cfb\u7edf\u5bfb\u627e\u5e76\u6e05\u9664\u764c\u75c7\u3002<\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;line-height: 2em;letter-spacing: 1px;text-indent: 2em;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;line-height: 2em;letter-spacing: 1px;text-indent: 2em;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 16px;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u7814\u7a76\u8005\u53d1\u73b0\uff0c\u53e6\u5916\u4e00\u79cd\u540d\u4e3aCD103\u7684\u7ec6\u80de\u8868\u9762\u86cb\u767d\u6216\u8bb8\u5c31\u662f\u4e00\u79cd\u5f52\u5de2\u4fe1\u53f7\uff0c\u5f53GARP\u5728Treg\u7ec6\u80de\u8868\u9762\u4e0a\u8868\u8fbe\u65f6\uff0c\u5176\u5c31\u4f1a\u6293\u53d6\u5176\u5b83\u7ec6\u80de\u6240\u5206\u6ccc\u7684TGF-\u03b2\uff0c\u8fd9\u5c31\u4f1a\u4fc3\u8fdbCD103\u7684\u8868\u8fbe\u88ab\u4e0a\u8c03\uff0c\u800c\u5bf9\u4e8eTreg\u7ec6\u80de\u800c\u8a00\u8fd9\u5c31\u597d\u50cf\u662f\u80a0\u9053\u4e2d\u7684\u201c\u90ae\u653f\u7f16\u7801\u201d\u3002\u8fd9\u9879\u7814\u7a76\u4e2d\uff0c\u7814\u7a76\u4eba\u5458\u9996\u6b21\u63ed\u793a\u4e86GARP\u5728\u8c03\u8282\u7ed3\u80a0Treg\u7ec6\u80de\u6d3b\u6027\u4e0a\u6240\u626e\u6f14\u7684\u5173\u952e\u89d2\u8272\uff0c\u4e0b\u4e00\u6b65\u7814\u7a76\u8005\u5c06\u4f1a\u5bf9\u4eba\u7c7b\u7ed3\u80a0\u764cTreg\u7ec6\u80de\u4e2dGARP\u5b58\u5728\u7684\u7279\u6027\u8fdb\u884c\u5206\u6790\u5e76\u9776\u5411\u4f5c\u7528GARP\u3002<\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;line-height: 2em;letter-spacing: 1px;text-indent: 2em;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;line-height: 2em;letter-spacing: 1px;text-indent: 2em;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 16px;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u6700\u540e\u7814\u7a76\u8005Li\u8bf4\u9053\uff0c\u7814\u7a76\u7ed3\u679c\u8868\u660e\uff0c\u7ed3\u80a0\u764c\u60a3\u8005\u673a\u4f53\u4e2dTGF-\u03b2\u7684\u6c34\u5e73\u8f83\u9ad8\uff0c\u5176\u4f1a\u4e0a\u8c03Treg\u7ec6\u80de\uff0c\u8fd9\u6216\u8bb8\u5c31\u662f\u4e3a\u4f55\u5f88\u591a\u60a3\u8005\u5bf9PD-1\u7597\u6cd5\u6ca1\u6709\u53cd\u5e94\u7684\u539f\u56e0\u4e4b\u4e00\uff0c\u7136\u800c\u8fd9\u4e9b\u60a3\u8005\u4e5f\u5f88\u6709\u53ef\u80fd\u662f\u6297GARP\u7597\u6cd5\u6cbb\u7597\u6548\u679c\u5f88\u597d\u7684\u4e00\u90e8\u5206\u4eba\u7fa4\u3002<\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;line-height: 2em;letter-spacing: 1px;text-indent: 2em;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;text-indent: 0em;line-height: normal;letter-spacing: 0.5px;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;text-indent: 2em;color: rgb(136, 136, 136);font-size: 14px;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u539f\u59cb\u51fa\u5904\uff1aMohammad Salem, Caroline Wallace, Maria Velegraki, et al. GARP Dampens Cancer Immunity by Sustaining Function and Accumulation of Regulatory T s in the Colon. Cancer Research, 2019; 79 (6): 1178 DOI:10.1158\/0008-5472.CAN-18-2623<\/span><\/p>\n<\/section>\n<p style=\"max-width: 100%;min-height: 1em;font-size: 16px;letter-spacing: 0.544px;white-space: normal;background-color: rgb(255, 255, 255);font-family: \u5fae\u8f6f\u96c5\u9ed1;line-height: 32px;text-align: center;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 20px;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box;text-indent: 27px;letter-spacing: 0.54px;widows: 1;font-size: 18px;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;color: rgb(0, 209, 0);box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u57f9\u8bad\u63a8\u8350<\/span><\/strong><\/span><br style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;font-size: 16px;letter-spacing: 0.544px;white-space: normal;background-color: rgb(255, 255, 255);font-family: \u5fae\u8f6f\u96c5\u9ed1;line-height: 32px;text-align: center;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><a href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MjM5NTI3MDE0NQ==&amp;mid=2653622204&amp;idx=8&amp;sn=557d45528da9fef4115187e3be05efc3&amp;chksm=bd24b4d28a533dc45bbc1762bf8ec6e76306c6557755276531dab9a5d734770ba71efb84303a&amp;scene=21#wechat_redirect\" target=\"_blank\"   style=\"-webkit-tap-highlight-color: rgba(0, 0, 0, 0);max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 15px;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;-webkit-tap-highlight-color: rgba(0, 0, 0, 0);box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u836f\u4f01\u516c\u7528\u5de5\u7a0b\u8bbe\u8ba1\u3001\u9a8c\u8bc1\u53ca\u65e5\u5e38\u7ba1\u7406\u7ef4\u62a4\uff08\u6b66\u6c49\uff09\u6280\u672f\u4ea4\u6d41\u4f1a<\/span><\/strong><\/span><\/a><br style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;font-size: 16px;letter-spacing: 0.544px;white-space: normal;background-color: rgb(255, 255, 255);font-family: \u5fae\u8f6f\u96c5\u9ed1;line-height: 32px;text-align: center;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><a href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MjM5NTI3MDE0NQ==&amp;mid=2653622147&amp;idx=4&amp;sn=1d1a215a0fba530345b894ef7b3883f6&amp;chksm=bd24b4ed8a533dfbf465b5bd88e1c507f3c88ff2e92f0e3d0c9af60add4ad9c79ed55249bf83&amp;scene=21#wechat_redirect\" target=\"_blank\"   style=\"-webkit-tap-highlight-color: rgba(0, 0, 0, 0);max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 15px;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;-webkit-tap-highlight-color: rgba(0, 0, 0, 0);box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u836f\u4f01\u5982\u4f55\u5f00\u5c55\u4e34\u5e8a\u524d\u5b89\u5168\u6027\u7814\u7a76\u4e13\u9898\u57f9\u8bad\u73ed\uff08ICH S\u6307\u5bfc\uff09<\/span><\/strong><\/span><\/a><br style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;font-size: 16px;letter-spacing: 0.544px;white-space: normal;background-color: rgb(255, 255, 255);font-family: \u5fae\u8f6f\u96c5\u9ed1;line-height: 32px;text-align: center;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><a href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MjM5NTI3MDE0NQ==&amp;mid=2653622410&amp;idx=6&amp;sn=7984f227ca630ba102ba0b247574d26b&amp;chksm=bd24abe48a5322f2ee4905ae29c2aac638fa7309c19dfdbd86316a8515a9799f4add113bb2f7&amp;scene=21#wechat_redirect\" target=\"_blank\"   style=\"-webkit-tap-highlight-color: rgba(0, 0, 0, 0);max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u201c\u6570\u636e\u5b8c\u6574\u6027\u53ca\u8ba1\u7b97\u673a\u5316\u7cfb\u7edf\u9a8c\u8bc1\u201d\u6280\u672f\u4ea4\u6d41\u4f1a<\/a><\/strong><\/p>\n<p style=\"max-width: 100%;min-height: 1em;font-size: 16px;letter-spacing: 0.544px;white-space: normal;background-color: rgb(255, 255, 255);font-family: \u5fae\u8f6f\u96c5\u9ed1;line-height: 32px;text-align: center;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 15px;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><a href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MzA5MDY4MDQ1NQ==&amp;mid=2649834371&amp;idx=6&amp;sn=58a1eeec283acc3cd2d496b9697c0363&amp;chksm=88021e6bbf75977d8a6ec44b1e420eacbae4290e187bfc82a3702d2eab2df38c3478b732b026&amp;scene=21#wechat_redirect\" target=\"_blank\"   style=\"-webkit-tap-highlight-color: rgba(0, 0, 0, 0);max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u65b0\u6cd5\u89c4\u4e0b\u836f\u54c1\u6ce8\u518c\u7533\u62a5\u7684\u91cd\u70b9\u96be\u70b9\u5206\u6790\u4e13\u9898\u7814\u4fee\u73ed<\/a><\/span><\/strong><\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;font-size: 16px;letter-spacing: 0.544px;white-space: normal;background-color: rgb(255, 255, 255);font-family: \u5fae\u8f6f\u96c5\u9ed1;line-height: 32px;text-align: center;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 15px;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><a href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MjM5NTI3MDE0NQ==&amp;mid=2653622410&amp;idx=5&amp;sn=8f89aee1ffe1990e50018ff51c1d3bed&amp;chksm=bd24abe48a5322f22b977a9ef82f85a96ae40ed017d5a1545a71e52f915c927477bc01b8aade&amp;scene=21#wechat_redirect\" target=\"_blank\"   style=\"-webkit-tap-highlight-color: rgba(0, 0, 0, 0);max-width: 100%;font-size: 16px;letter-spacing: 0.544px;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u57fa\u4e8e\u5927\u6570\u636e\u5b8c\u6574\u6027\u7684\u98ce\u9669\u5e94\u5bf9OOS\/OOT\u8c03\u67e5\u4e0eCAPA\u201d\u6280\u672f\u4ea4\u6d41\u4f1a<\/strong><\/a><\/span><\/strong><\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;font-size: 16px;white-space: normal;background-color: rgb(255, 255, 255);color: rgb(82, 82, 82);widows: 1;font-family: \u5fae\u8f6f\u96c5\u9ed1;text-align: center;letter-spacing: 0.54px;line-height: normal;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><strong style=\"max-width: 100%;color: rgb(255, 41, 65);line-height: 25.6px;font-size: 18px;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u8bc6\u522b\u5fae\u4fe1\u4e8c\u7ef4\u7801\uff0c\u6dfb\u52a0\u5c0f\u7f16\uff0c\u7b26\u5408\u6761\u4ef6\u8005\u5373\u53ef\u52a0\u5165\u751f\u7269\u5236\u54c1\u5fae\u4fe1\u7fa4\uff01<\/strong><\/p>\n<section label=\"Powered by 135editor.com\"  style=\"max-width: 100%;font-size: 16px;white-space: normal;background-color: rgb(255, 255, 255);color: rgb(82, 82, 82);widows: 1;font-family: \u5fae\u8f6f\u96c5\u9ed1;letter-spacing: 0.54px;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<section label=\"Powered by 135editor.com\"  style=\"max-width: 100%;line-height: 25.6px;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<p style=\"max-width: 100%;min-height: 1em;text-align: center;line-height: 25.6px;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;color: rgb(0, 128, 255);font-size: 20px;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u8bf7\u6ce8\u660e\uff1a\u59d3\u540d+\u7814\u7a76\u65b9\u5411\uff01<\/strong><\/span><\/p>\n<section label=\"Powered by 135editor.com\"  style=\"max-width: 100%;letter-spacing: 0.54px;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<section label=\"Powered by 135editor.com\"  style=\"max-width: 100%;line-height: 25.6px;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<p style=\"max-width: 100%;min-height: 1em;text-align: center;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><img class=\"\"       style=\"box-sizing: border-box !important;overflow-wrap: break-word !important;visibility: visible !important;width: 253px !important;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2019\/05\/6-1558083983.jpeg\" alt=\"\u7a81\u7834\uff01\u79d1\u5b66\u5bb6\u9274\u522b\u51fa\u764c\u75c7\u514d\u75ab\u7597\u6cd5\u7684\u6f5c\u5728\u65b0\u578b\u9776\u70b9\uff1aGARP\" title=\"\u7a81\u7834\uff01\u79d1\u5b66\u5bb6\u9274\u522b\u51fa\u764c\u75c7\u514d\u75ab\u7597\u6cd5\u7684\u6f5c\u5728\u65b0\u578b\u9776\u70b9\uff1aGARP\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;text-align: center;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><img width=\"555\"    class=\"\"  style=\"letter-spacing: 0.54px;line-height: 25.6px;text-indent: 0em;vertical-align: middle;box-sizing: border-box !important;overflow-wrap: break-word !important;visibility: visible !important;max-height: 1.2em !important;width: 640px !important;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2019\/05\/7-1558083984.png\" alt=\"\u7a81\u7834\uff01\u79d1\u5b66\u5bb6\u9274\u522b\u51fa\u764c\u75c7\u514d\u75ab\u7597\u6cd5\u7684\u6f5c\u5728\u65b0\u578b\u9776\u70b9\uff1aGARP\" title=\"\u7a81\u7834\uff01\u79d1\u5b66\u5bb6\u9274\u522b\u51fa\u764c\u75c7\u514d\u75ab\u7597\u6cd5\u7684\u6f5c\u5728\u65b0\u578b\u9776\u70b9\uff1aGARP\"  \/><br style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"  \/><\/p>\n<\/section>\n<\/section>\n<section  label=\"Powered by 135editor.com\" style=\"max-width: 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