{"id":106834,"date":"2019-04-05T00:00:50","date_gmt":"2019-05-17T09:12:40","guid":{"rendered":"http:\/\/www.05921.net\/index.php\/106834\/"},"modified":"2019-05-17T17:12:42","modified_gmt":"2019-05-17T09:12:42","slug":"f8617f80d0","status":"publish","type":"post","link":"https:\/\/www.05921.net\/index.php\/106834\/","title":{"rendered":"AACR | \u4f60\u77e5\u9053\u8fd9\u4e9bCAR-T\u548c\u80bf\u7624\u75ab\u82d7\u9886\u57df\u7684\u6700\u65b0\u8fdb\u5c55\u4e48\uff1f"},"content":{"rendered":"<div class=\"bpp-post-content\">\n<p style=\"line-height: 1.75em;\"><span style=\"font-size: 15px;\">\u5728\u764c\u75c7\u514d\u75ab\u7597\u6cd5\u9886\u57df\uff0c\u5bf9CAR-T\u7597\u6cd5\u548c\u80bf\u7624\u75ab\u82d7\u7684\u7814\u7a76\u4e5f\u53d6\u5f97\u4e86\u53ef\u559c\u7684\u8fdb\u5c55\u3002<\/span><span style=\"font-size: 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style=\"\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2019\/05\/5-1558084361.png\" alt=\"AACR | \u4f60\u77e5\u9053\u8fd9\u4e9bCAR-T\u548c\u80bf\u7624\u75ab\u82d7\u9886\u57df\u7684\u6700\u65b0\u8fdb\u5c55\u4e48\uff1f\" title=\"AACR | \u4f60\u77e5\u9053\u8fd9\u4e9bCAR-T\u548c\u80bf\u7624\u75ab\u82d7\u9886\u57df\u7684\u6700\u65b0\u8fdb\u5c55\u4e48\uff1f\"  \/><\/p>\n<p style=\"line-height: 1.75em;\"><span style=\"font-size: 15px;\"><\/span><br  \/><\/p>\n<p style=\"line-height: 1.75em;\"><span style=\"font-size: 15px;\">\u5728\u7eaa\u5ff5\u65af\u9686\u51ef\u7279\u7433\u764c\u75c7\u4e2d\u5fc3\u7684\u4e00\u98791\u671f\u4e34\u5e8a\u7814\u7a76\u4e2d\uff0c\u7814\u7a76\u4eba\u5458\u4f7f\u7528\u540d\u4e3alcasM28z\u7684CAR-T\u7ec6\u80de\u5bf9\u6076\u6027\u80f8\u819c\u95f4\u76ae\u7624\u60a3\u8005\u8fdb\u884c\u6cbb\u7597\u3002\u8fd9\u79cd\u764c\u75c7\u662f\u4e00\u79cd\u4fb5\u88ad\u6027\u975e\u5e38\u5f3a\u7684\u80ba\u764c\u3002<strong>LcasM28z\u662f\u4e00\u79cd\u9776\u5411\u95f4\u76ae\u7d20\uff08mesothelin\uff09\u7684CAR-T\u7ec6\u80de\u7597\u6cd5\uff0c\u540c\u65f6\u5728\u7ec6\u80de\u4e2d\u52a0\u5165\u4e86\u53ef\u4ee5\u5173\u95edCAR-T\u7ec6\u80de\u529f\u80fd\u7684\u5b89\u5168\u5f00\u5173\u3002<\/strong><\/span><\/p>\n<p style=\"line-height: 1.75em;\"><span style=\"font-size: 15px;\"><br  \/><\/span><\/p>\n<p style=\"line-height: 1.75em;\"><span style=\"font-size: 15px;\">\u5728\u8fd9\u9879\u8bd5\u9a8c\u4e2d\uff0c<strong>21\u540d\u60a3\u8005\u63a5\u53d7\u4e86CAR-T\u7597\u6cd5\u7684\u6cbb\u7597\uff0c\u572838\u5468\u4e4b\u540e\uff0c\u5176\u4e2d13\u540d\u60a3\u8005\u7684\u5916\u5468\u8840\u4e2d\u4f9d\u7136\u6301\u7eed\u5b58\u5728CAR-T\u7ec6\u80de<\/strong>\uff0c\u800c\u4e14\u8fd9\u4e9b\u60a3\u8005\u4f53\u5185\u95f4\u76ae\u7d20\u76f8\u5173\u80bd\u6c34\u5e73\u4e0b\u964d50%\uff0c\u5e76\u4e14\u6210\u50cf\u7814\u7a76\u663e\u793a\u80bf\u7624\u51fa\u73b0\u7f29\u5c0f\u3002<\/span><\/p>\n<p style=\"line-height: 1.75em;\"><span style=\"font-size: 15px;\"><br  \/><\/span><\/p>\n<p style=\"text-align: center;\"><img class=\"rich_pages\"       style=\"\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2019\/05\/6-1558084361.png\" alt=\"AACR | \u4f60\u77e5\u9053\u8fd9\u4e9bCAR-T\u548c\u80bf\u7624\u75ab\u82d7\u9886\u57df\u7684\u6700\u65b0\u8fdb\u5c55\u4e48\uff1f\" title=\"AACR | 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15px;\">\u5728\u8fd9\u9879\u8bd5\u9a8c\u4e2d\uff0c\u60a3\u8005\u63a5\u53d7\u4e0d\u540c\u5242\u91cf\u7684\u75ab\u82d7\u63a5\u79cd\uff0c\u63a5\u79cd\u5b8c\u62106-8\u5468\u540e\uff0c\u5f00\u59cb\u63a5\u53d7\u6807\u51c6\u7597\u6cd5\u7684\u6cbb\u7597\u3002\u8bd5\u9a8c\u7ed3\u679c\u8868\u660e\uff0c\u63a5\u53d7\u6700\u9ad8\u5242\u91cf\u75ab\u82d7\u63a5\u79cd\u7684\u60a3\u8005\uff0c<strong>\u4e2d\u4f4d\u603b\u751f\u5b58\u671f\u8fbe\u523021.9\u4e2a\u6708\uff0c\u9ad8\u4e8e\u5386\u53f2\u4e0a\u53ea\u63a5\u53d7\u6807\u51c6\u7597\u6cd5\u60a3\u8005\u7684\u8868\u73b0\uff0814.6\u4e2a\u6708\uff09<\/strong>\u3002\u8fd9\u4e9b\u60a3\u8005\u7684PFS\u8fbe\u523010.4\u4e2a\u6708\uff0c\u4e5f\u9ad8\u4e8e\u53ea\u63a5\u53d7\u6807\u51c6\u7597\u6cd5\u7684\u60a3\u8005\uff086.9\u4e2a\u6708\uff09\u3002<\/span><\/p>\n<p style=\"line-height: 1.75em;\"><span style=\"font-size: 15px;\"><br  \/><\/span><\/p>\n<p style=\"text-align: center;\"><img class=\"rich_pages\"           style=\"width: 556px;height: 120px;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2019\/05\/0-1558084362.jpeg\" alt=\"AACR | \u4f60\u77e5\u9053\u8fd9\u4e9bCAR-T\u548c\u80bf\u7624\u75ab\u82d7\u9886\u57df\u7684\u6700\u65b0\u8fdb\u5c55\u4e48\uff1f\" title=\"AACR | \u4f60\u77e5\u9053\u8fd9\u4e9bCAR-T\u548c\u80bf\u7624\u75ab\u82d7\u9886\u57df\u7684\u6700\u65b0\u8fdb\u5c55\u4e48\uff1f\"  \/><\/p>\n<p style=\"line-height: 1.75em;\"><span style=\"font-size: 15px;\"><\/span><br  \/><\/p>\n<p style=\"line-height: 1.75em;\"><span style=\"font-size: 15px;\">\u5eb7\u5948\u5c14\u533b\u5b66\u9662\u7684\u7814\u7a76\u4eba\u5458\u6c47\u62a5\u4e86\u4ed6\u4eec\u4f7f\u7528<strong>\u57fa\u4e8e\u65b0\u6297\u539f\u7684\u764c\u75c7\u75ab\u82d7\u6cbb\u7597\u6797\u5947\u7efc\u5408\u75c7<\/strong>\uff08Lynch 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microsatellite\uff09\u3002\u8fd9\u4e9b\u7f16\u7801\u533a\u5fae\u536b\u661f\u80fd\u591f\u751f\u6210\u65b0\u6297\u539f\uff0c\u5b83\u4eec\u53ef\u4ee5\u88ab\u60a3\u8005\u7684\u514d\u75ab\u7cfb\u7edf\u8bc6\u522b\uff0c\u4f46\u662f\u901a\u5e38\u4e0d\u80fd\u6fc0\u53d1\u8db3\u591f\u7684\u514d\u75ab\u53cd\u5e94\u6765\u9632\u6b62\u764c\u75c7\u7684\u53d1\u751f\u3002<\/span><\/p>\n<p style=\"line-height: 1.75em;\"><span style=\"font-size: 15px;\"><br  \/><\/span><\/p>\n<p style=\"line-height: 1.75em;\"><span style=\"font-size: 15px;\">\u7814\u7a76\u4eba\u5458\u5bf9\u6797\u5947\u7efc\u5408\u5f81\u60a3\u8005\u7684\u7f16\u7801\u533a\u5fae\u536b\u661f\u8fdb\u884c\u4e86\u7b5b\u9009\uff0c\u5e76\u4e14\u627e\u51fa\u80fd\u591f\u6fc0\u53d1\u5f3a\u529b\u514d\u75ab\u53cd\u5e94\u7684\u65b0\u6297\u539f\u4f5c\u4e3a\u80bf\u7624\u75ab\u82d7\u3002\u5728\u5c0f\u9f20\u8bd5\u9a8c\u4e2d\uff0c\u5c06\u8fd9\u4e9b\u80bf\u7624\u75ab\u82d7\u6ce8\u5c04\u5230\u6a21\u62df\u6797\u5947\u7efc\u5408\u5f81\u7684\u5c0f\u9f20\u4f53\u5185\uff0c<strong>\u80fd\u591f\u663e\u8457\u964d\u4f4e\u5c0f\u9f20\u80a0\u9053\u80bf\u7624\u8d1f\u62c5\uff0c\u5e76\u4e14\u63d0\u9ad8\u5c0f\u9f20\u7684\u751f\u5b58\u671f<\/strong>\u3002\u672a\u63a5\u53d7\u8fc7\u75ab\u82d7\u63a5\u79cd\u7684\u5c0f\u9f20\u5e73\u5747\u80a0\u9053\u80bf\u7624\u8d1f\u62c5\u4e3a61 mg\uff0c\u603b\u751f\u5b58\u671f\u4e3a241\u5929\uff0c\u800c\u63a5\u53d7\u8fc7\u75ab\u82d7\u63a5\u79cd\u7684\u5c0f\u9f20\u80a0\u9053\u80bf\u7624\u8d1f\u62c5\u4e3a31 mg\uff0c\u603b\u751f\u5b58\u671f\u4e3a380\u5929\u3002<\/span><\/p>\n<p><br  \/><\/p>\n<p style=\"line-height: normal;\"><span style=\"font-size: 10px;color: rgb(178, 178, 178);\">\u53c2\u8003\u8d44\u6599\uff1a<\/span><\/p>\n<p style=\"line-height: normal;\"><span style=\"font-size: 10px;color: rgb(178, 178, 178);\">[1] AACR: After blood cancer successes, CAR-T treatments see inroads for solid cancers. Retrieved April 1, 2019, from https:\/\/www.fiercebiotech.com\/biotech\/aacr-after-blood-cancer-successes-car-t-treatments-see-inroads-for-solid-cancers<\/span><\/p>\n<p style=\"line-height: normal;\"><span style=\"font-size: 10px;color: rgb(178, 178, 178);\">[2] Cancer preventive vaccine showed promising results in <\/span><span style=\"font-size: 10px;color: rgb(178, 178, 178);\">preclinical<\/span><span style=\"font-size: 10px;color: rgb(178, 178, 178);\"> model of Lynch syndrome. Retrieved April 1, 2019, from https:\/\/www.eurekalert.org\/pub_releases\/2019-04\/aafc-cpv032519.php<\/span><\/p>\n<p style=\"line-height: normal;\"><span style=\"font-size: 10px;color: rgb(178, 178, 178);\">[3] Imvax Announces Positive Results from Clinical Trial of Novel IGV-001 Autologous  Vaccine in Treating Patients with Newly Diagnosed Glioblastoma. Retrieved April 1, 2019, from https:\/\/www.apnews.com\/Globe%20Newswire\/7b54d703752ec0b4474ecc28db562391<\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;letter-spacing: 0.544px;white-space: normal;font-size: 15px;widows: 1;text-align: center;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><a href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MjM5NTI3MDE0NQ==&amp;mid=2653622481&amp;idx=1&amp;sn=833e123db4eb62553b5112060d1a965f&amp;chksm=bd24abbf8a5322a9d9a229b330229cfe380151be5593146f5daba4d2597f50872a1abd305f08&amp;scene=21#wechat_redirect\" target=\"_blank\"   style=\"-webkit-tap-highlight-color: rgba(0, 0, 0, 0);max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span class=\"js_jump_icon h5_image_link\"  style=\"max-width: 100%;line-height: 0;top: auto;left: auto;right: auto;bottom: auto;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><img class=\"rich_pages\"       style=\"box-sizing: border-box !important;overflow-wrap: break-word !important;visibility: visible !important;width: 677px !important;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2019\/05\/3-1558084362.jpeg\" alt=\"AACR | \u4f60\u77e5\u9053\u8fd9\u4e9bCAR-T\u548c\u80bf\u7624\u75ab\u82d7\u9886\u57df\u7684\u6700\u65b0\u8fdb\u5c55\u4e48\uff1f\" title=\"AACR | \u4f60\u77e5\u9053\u8fd9\u4e9bCAR-T\u548c\u80bf\u7624\u75ab\u82d7\u9886\u57df\u7684\u6700\u65b0\u8fdb\u5c55\u4e48\uff1f\"  \/><\/span><\/a><\/p>\n<p style=\"max-width: 100%;min-height: 1em;letter-spacing: 0.544px;white-space: normal;font-size: 15px;widows: 1;text-align: center;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 16px;color: rgb(255, 41, 65);box-sizing: border-box !important;overflow-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u70b9\u51fb\u56fe\u7247\u5373\u53ef\u62a5\u540d\u53c2\u52a0\uff01<\/strong><\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;font-size: 16px;letter-spacing: 0.544px;white-space: normal;font-family: \u5fae\u8f6f\u96c5\u9ed1;line-height: 32px;text-align: center;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 20px;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box;text-indent: 27px;letter-spacing: 0.54px;widows: 1;font-size: 18px;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;color: rgb(0, 209, 0);box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u57f9\u8bad\u63a8\u8350<\/span><\/strong><\/span><br style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;font-size: 16px;letter-spacing: 0.544px;white-space: normal;font-family: \u5fae\u8f6f\u96c5\u9ed1;line-height: 32px;text-align: center;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><a href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MjM5NTI3MDE0NQ==&amp;mid=2653622204&amp;idx=8&amp;sn=557d45528da9fef4115187e3be05efc3&amp;chksm=bd24b4d28a533dc45bbc1762bf8ec6e76306c6557755276531dab9a5d734770ba71efb84303a&amp;scene=21#wechat_redirect\" target=\"_blank\"   style=\"-webkit-tap-highlight-color: rgba(0, 0, 0, 0);max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 15px;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;-webkit-tap-highlight-color: rgba(0, 0, 0, 0);box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u836f\u4f01\u516c\u7528\u5de5\u7a0b\u8bbe\u8ba1\u3001\u9a8c\u8bc1\u53ca\u65e5\u5e38\u7ba1\u7406\u7ef4\u62a4\uff08\u6b66\u6c49\uff09\u6280\u672f\u4ea4\u6d41\u4f1a<\/span><\/strong><\/span><\/a><br style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;font-size: 16px;letter-spacing: 0.544px;white-space: normal;font-family: \u5fae\u8f6f\u96c5\u9ed1;line-height: 32px;text-align: center;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><a href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MjM5NTI3MDE0NQ==&amp;mid=2653622147&amp;idx=4&amp;sn=1d1a215a0fba530345b894ef7b3883f6&amp;chksm=bd24b4ed8a533dfbf465b5bd88e1c507f3c88ff2e92f0e3d0c9af60add4ad9c79ed55249bf83&amp;scene=21#wechat_redirect\" target=\"_blank\"   style=\"-webkit-tap-highlight-color: rgba(0, 0, 0, 0);max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span 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!important;\"><a href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MjM5NTI3MDE0NQ==&amp;mid=2653622410&amp;idx=6&amp;sn=7984f227ca630ba102ba0b247574d26b&amp;chksm=bd24abe48a5322f2ee4905ae29c2aac638fa7309c19dfdbd86316a8515a9799f4add113bb2f7&amp;scene=21#wechat_redirect\" target=\"_blank\"   style=\"-webkit-tap-highlight-color: rgba(0, 0, 0, 0);max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u201c\u6570\u636e\u5b8c\u6574\u6027\u53ca\u8ba1\u7b97\u673a\u5316\u7cfb\u7edf\u9a8c\u8bc1\u201d\u6280\u672f\u4ea4\u6d41\u4f1a<\/a><\/strong><\/p>\n<p style=\"max-width: 100%;min-height: 1em;font-size: 16px;letter-spacing: 0.544px;white-space: normal;font-family: \u5fae\u8f6f\u96c5\u9ed1;line-height: 32px;text-align: center;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 15px;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><a href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MzA5MDY4MDQ1NQ==&amp;mid=2649834371&amp;idx=6&amp;sn=58a1eeec283acc3cd2d496b9697c0363&amp;chksm=88021e6bbf75977d8a6ec44b1e420eacbae4290e187bfc82a3702d2eab2df38c3478b732b026&amp;scene=21#wechat_redirect\" target=\"_blank\"   style=\"-webkit-tap-highlight-color: rgba(0, 0, 0, 0);max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u65b0\u6cd5\u89c4\u4e0b\u836f\u54c1\u6ce8\u518c\u7533\u62a5\u7684\u91cd\u70b9\u96be\u70b9\u5206\u6790\u4e13\u9898\u7814\u4fee\u73ed<\/a><\/span><\/strong><\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;font-size: 16px;letter-spacing: 0.544px;white-space: normal;font-family: \u5fae\u8f6f\u96c5\u9ed1;line-height: 32px;text-align: center;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 15px;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><a href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MjM5NTI3MDE0NQ==&amp;mid=2653622410&amp;idx=5&amp;sn=8f89aee1ffe1990e50018ff51c1d3bed&amp;chksm=bd24abe48a5322f22b977a9ef82f85a96ae40ed017d5a1545a71e52f915c927477bc01b8aade&amp;scene=21#wechat_redirect\" target=\"_blank\"   style=\"-webkit-tap-highlight-color: rgba(0, 0, 0, 0);max-width: 100%;font-size: 16px;letter-spacing: 0.544px;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u57fa\u4e8e\u5927\u6570\u636e\u5b8c\u6574\u6027\u7684\u98ce\u9669\u5e94\u5bf9OOS\/OOT\u8c03\u67e5\u4e0eCAPA\u201d\u6280\u672f\u4ea4\u6d41\u4f1a<\/strong><\/a><\/span><\/strong><\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;font-size: 16px;white-space: normal;color: rgb(82, 82, 82);widows: 1;font-family: \u5fae\u8f6f\u96c5\u9ed1;text-align: center;letter-spacing: 0.54px;line-height: normal;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><strong style=\"max-width: 100%;color: rgb(255, 41, 65);line-height: 25.6px;font-size: 18px;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u8bc6\u522b\u5fae\u4fe1\u4e8c\u7ef4\u7801\uff0c\u6dfb\u52a0\u5c0f\u7f16\uff0c\u7b26\u5408\u6761\u4ef6\u8005\u5373\u53ef\u52a0\u5165\u751f\u7269\u5236\u54c1\u5fae\u4fe1\u7fa4\uff01<\/strong><\/p>\n<section label=\"Powered by 135editor.com\"  style=\"max-width: 100%;font-size: 16px;white-space: normal;color: rgb(82, 82, 82);widows: 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0.54px;line-height: 25.6px;text-indent: 0em;vertical-align: middle;box-sizing: border-box !important;overflow-wrap: break-word !important;visibility: visible !important;max-height: 1.2em !important;width: 640px !important;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2019\/05\/10-1558084362.png\" alt=\"AACR | \u4f60\u77e5\u9053\u8fd9\u4e9bCAR-T\u548c\u80bf\u7624\u75ab\u82d7\u9886\u57df\u7684\u6700\u65b0\u8fdb\u5c55\u4e48\uff1f\" title=\"AACR | \u4f60\u77e5\u9053\u8fd9\u4e9bCAR-T\u548c\u80bf\u7624\u75ab\u82d7\u9886\u57df\u7684\u6700\u65b0\u8fdb\u5c55\u4e48\uff1f\"  \/><br style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"  \/><\/p>\n<\/section>\n<\/section>\n<section  label=\"Powered by 135editor.com\" style=\"max-width: 100%;letter-spacing: 0.544px;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<section label=\"Powered by 135editor.com\"  style=\"max-width: 100%;line-height: 25.6px;letter-spacing: 0.54px;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<section label=\"Powered by 135editor.com\"  style=\"max-width: 100%;line-height: 25.6px;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<section style=\"max-width: 100%;line-height: 25.6px;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<section style=\"margin-top: 0.5em;margin-bottom: 0.5em;max-width: 100%;text-align: center;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<section style=\"margin: -0.9em auto 0.9em;max-width: 100%;width: 0.6em;height: 0.6em;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<section style=\"margin-left: 1px;max-width: 100%;border-radius: 100%;width: 9.59px;height: 9.59px;background-color: rgb(170, 33, 94);box-sizing: border-box !important;overflow-wrap: break-word !important;\"><br  style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"  \/><\/section>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"max-width: 100%;font-size: 14px;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<section style=\"margin-top: 10px;margin-bottom: 10px;padding-left: 4px;max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<section style=\"margin-bottom: 0.2em;max-width: 100%;width: 666px;vertical-align: bottom;display: inline-block;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<section style=\"max-width: 100%;width: 599.39px;border-top: 1px solid rgb(170, 33, 94);box-sizing: border-box !important;overflow-wrap: break-word !important;\"><\/section>\n<section style=\"margin-top: -4px;margin-right: -4px;max-width: 100%;border-radius: 100%;width: 8px;height: 8px;background-color: rgb(170, 33, 94);box-sizing: border-box !important;overflow-wrap: break-word !important;\"><\/section>\n<\/section>\n<section style=\"margin-top: -1.5em;max-width: 100%;text-align: right;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<section style=\"max-width: 100%;border-radius: 100%;width: 2em;height: 2em;text-align: center;color: rgb(255, 255, 255);line-height: 2em;vertical-align: top;display: inline-block;background-color: rgb(170, 33, 94);box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u7248<\/section>\n<\/section>\n<section style=\"max-width: 100%;border-radius: 100%;width: 2em;height: 2em;text-align: center;color: rgb(255, 255, 255);line-height: 2em;vertical-align: top;display: inline-block;background-color: rgb(170, 33, 94);box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word 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