{"id":107855,"date":"2019-05-10T00:00:50","date_gmt":"2019-05-17T09:19:27","guid":{"rendered":"http:\/\/www.05921.net\/index.php\/107855\/"},"modified":"2019-05-17T17:19:29","modified_gmt":"2019-05-17T09:19:29","slug":"4baf34e991","status":"publish","type":"post","link":"https:\/\/www.05921.net\/index.php\/107855\/","title":{"rendered":"\u6bcd\u6e90\u6297\u4f53\u5bf9\u8f6e\u72b6\u75c5\u6bd2\u75ab\u82d7\u6709\u6548\u6027\u7684\u5f71\u54cd"},"content":{"rendered":"<div class=\"bpp-post-content\">\n<section  class=\"\"  font-size=\"14px\" style=\"max-width: 100%;letter-spacing: 0.544px;white-space: normal;background-color: rgb(255, 255, 255);box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<section  style=\"margin: 20px auto;max-width: 100%;width: 643.125px;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<section style=\"margin-bottom: -8px;max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word 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!important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;font-family: \u5b8b\u4f53;font-size: 14px;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u8bb8\u591a\u79d1\u5b66\u5bb6\u5bf9\u4e73\u6c41\u4e2dIgA\u6297\u4f53\u6c34\u5e73\u4e0e\u8f6e\u72b6\u75c5\u6bd2\u75ab\u82d7\u7684\u6709\u6548\u6027\u5173\u7cfb\u8fdb\u884c\u4e86\u5927\u91cf\u7684\u7814\u7a76\uff61Moon\u7b49<sup style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">[1]<\/sup>\u8bc4\u4ef7\u4e86\u4e73\u6c41\u5bf9\u8f6e\u72b6\u75c5\u6bd2\u51cf\u6bd2\u6d3b\u75ab\u82d7\u7684\u6709\u6548\u6027\u7684\u6291\u5236\u4f5c\u7528,\u5e76\u4e14\u5728\u68c0\u6d4b\u4e73\u6c41\u4e2d\u75ab\u82d7\u4e2d\u548c\u6297\u4f53\u6ef4\u5ea6\u65f6\u663e\u793a,\u5370\u5ea6\u6bcd\u4eb2\u4e73\u6c41\u4e2d\u7684\u75ab\u82d7\u4e2d\u548c\u6297\u4f53\u6ef4\u5ea6\u663e\u8457\u9ad8\u4e8e\u7f8e\u56fd\u7684\u6bcd\u4eb2\u4e73\u6c41\u4e2d\u7684\u6297\u4f53\u6ef4\u5ea6,\u5e76\u4e14\u6700\u7ec8\u7684\u514d\u75ab\u7ed3\u679c\u663e\u793a,\u5370\u5ea6\u7684\u5a74\u513f\u5728\u63a5\u79cdRV1\uff64RV5\u548c116E\u540e\u7684\u514d\u75ab\u5e94\u7b54\u6548\u7387\u90fd\u6bd4\u7f8e\u56fd\u7684\u5a74\u513f\u4f4e1-2\u500d\u5de6\u53f3\uff61<\/span><\/p>\n<p style=\"margin-top: 10px;margin-bottom: 10px;max-width: 100%;min-height: 1em;letter-spacing: 0.544px;white-space: normal;background-color: rgb(255, 255, 255);line-height: 1.75em;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;font-family: \u5b8b\u4f53;font-size: 14px;box-sizing: border-box !important;overflow-wrap: break-word !important;\">Chilengi\u7b49\u6bd4\u8f83\u4e86\u8d5e\u6bd4\u4e9a\u9996\u90fd\u5362\u8428\u5361\u57ce\u5e02\u7684420\u4f8b\u6bcd\u5a74\u961f\u5217\u4e2d\u4e73\u6c41\u4e2d\u7279\u5f02\u6027\u6297\u4f53IgA\u7684\u6ef4\u5ea6\u5bf9\u5355\u4ef7\u82d7Rotarix\u00ae\u7684\u5f71\u54cd\u60c5\u51b5,\u7ed3\u679c\u53d1\u73b0,\u514d\u75ab\u524d\u4e73\u6c41\u4e2d\u7279\u5f02\u6027IgA\u6297\u4f53\u6ef4\u5ea6\u8d8a\u9ad8,\u5a74\u513f\u4ea7\u751f\u6297\u4f53\u7684\u6bd4\u4f8b\u8d8a\u4f4e\uff61<\/span><\/p>\n<p style=\"margin-top: 20px;max-width: 100%;min-height: 1em;letter-spacing: 0.544px;white-space: normal;background-color: rgb(255, 255, 255);box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 15px;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;font-family: \u5b8b\u4f53;box-sizing: border-box !important;overflow-wrap: break-word !important;\">3.\u6bcd\u4e73\u5582\u517b\u65b9\u5f0f\u5bf9\u8f6e\u72b6\u75c5\u6bd2\u75ab\u82d7\u6709\u6548\u6027\u7684\u5f71\u54cd<\/span><\/strong><\/span><\/p>\n<p style=\"margin-top: 10px;margin-bottom: 10px;max-width: 100%;min-height: 1em;letter-spacing: 0.544px;white-space: normal;background-color: rgb(255, 255, 255);line-height: 1.75em;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 14px;font-family: \u5b8b\u4f53;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u5728\u6b27\u6d32,\u6bcd\u4e73\u5582\u517b\u548c\u975e\u6bcd\u4e73\u5582\u517b\u7684\u5a74\u513f\u95f4\u7684\u8840\u6e05\u5b66\u8f6c\u6362\u5e76\u6ca1\u6709\u663e\u8457\u6027\u5dee\u5f02,\u4f46\u662f\u6709\u90e8\u5206\u7ed3\u679c\u663e\u793a,\u975e\u6bcd\u4e73\u5582\u517b\u7684\u5a74\u513f\u7684\u8840\u6e05\u8f6c\u5316\u7387\u6709\u9ad8\u4e8e\u5b8c\u5168\u6bcd\u4e73\u5582\u517b\u7684\u5a74\u513f\u8d8b\u52bf<sup style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">[17-18]<\/sup>\uff61\u5fb7\u56fd\u7684Adlhoch\u7b49[29]\u5728\u5bf9\u5a74\u513f\u8fdb\u884c\u4e2a\u6848\u5bf9\u7167\u7814\u7a76\u4e2d,\u53d1\u73b0\u5728\u4e94\u4ef7\u82d7Rotateq\u00ae\u75ab\u82d7\u63a5\u79cd\u671f\u95f4,\u5927\u91cf\u6bcd\u4e73\u5582\u517b\u7684\u5a74\u513f\u5b58\u5728\u7740\u75ab\u82d7\u5e94\u7b54\u8840\u6e05\u9633\u8f6c\u7387\u8f83\u4f4e\u7684\u73b0\u8c61\uff61\u4f46\u662f,\u8fd9\u4e9b\u56fd\u5bb6\u6bcd\u4e73\u4e2d\u8f6e\u72b6\u75c5\u6bd2\u6297\u4f53\u6ef4\u5ea6\u8f83\u4f4e,\u53ef\u80fd\u4f1a\u5bfc\u81f4\u6bcd\u4e73\u5582\u517b\u4e0e\u5426\u5a74\u513f\u514d\u75ab\u5e94\u7b54\u6c34\u5e73\u65e0\u663e\u8457\u5dee\u5f02\uff61<\/span><\/p>\n<p style=\"margin-top: 10px;margin-bottom: 10px;max-width: 100%;min-height: 1em;letter-spacing: 0.544px;white-space: normal;background-color: rgb(255, 255, 255);line-height: 1.75em;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 14px;font-family: \u5b8b\u4f53;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u800c\u5728\u4f4e\u6536\u5165\u56fd\u5bb6,\u7531\u4e8e\u6bcd\u4e73\u5582\u517b\u7684\u6bd4\u4f8b\u5f88\u9ad8,\u5f88\u96be\u76f4\u63a5\u6bd4\u8f83\u6bcd\u4e73\u4e0e\u975e\u6bcd\u4e73\u7ec4\u5a74\u513f\u514d\u75ab\u5e94\u7b54\u6c34\u5e73\u7684\u5dee\u5f02\uff61\u5728\u8fd9\u4e9b\u4f4e\u6536\u5165\u56fd\u5bb6,\u4f8b\u5982\u5357\u975e\uff64\u5370\u5ea6\uff64\u5df4\u57fa\u65af\u5766,\u76ee\u524d\u4e3b\u8981\u662f\u901a\u8fc7\u5728\u63a5\u79cd\u8f6e\u72b6\u75c5\u6bd2\u75ab\u82d7\u65f6\u505c\u6b62\u54fa\u4e73,\u4ee5\u7814\u7a76\u6bcd\u4e73\u5bf9\u8f6e\u72b6\u75c5\u6bd2\u75ab\u82d7\u6709\u6548\u6027\u7684\u5f71\u54cd\uff61<\/span><\/p>\n<p style=\"margin-top: 10px;margin-bottom: 10px;max-width: 100%;min-height: 1em;letter-spacing: 0.544px;white-space: normal;background-color: rgb(255, 255, 255);line-height: 1.75em;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 14px;font-family: \u5b8b\u4f53;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u5728\u8fd9\u4e9b\u56fd\u5bb6\u5f00\u5c55\u63a5\u79cd\u5355\u4ef7\u82d7Rotarix\u00ae\u65f6\u505c\u6b62\u54fa\u4e73\u7684\u4e34\u5e8a\u8bd5\u9a8c,\u968f\u673a\u5c06\u8fd93\u4e2a\u56fd\u5bb6\u7684\u6bcd\u5a74\u5206\u4e3a3\u4e2a\u7ec4,\u5373\u63a5\u79cd\u75ab\u82d7\u514d\u75ab\u524d\u540e1\u5c0f\u65f6\u5185\u505c\u6b62\u54fa\u4e73\u7ec4,\u63a5\u79cd\u75ab\u82d7\u514d\u75ab\u524d\u540e\u534a\u5c0f\u65f6\u5185\u505c\u6b62\u54fa\u4e73\u7ec4\u548c\u6b63\u5e38\u54fa\u4e73\u5582\u517b\u7ec4\uff61\u7ed3\u679c\u663e\u793a,3\u4e2a\u7ec4\u4e4b\u95f4\u7684\u8840\u6e05\u8f6c\u5316\u7387\u65e0\u660e\u663e\u533a\u522b<sup style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">[19]<\/sup>\uff61\u4f46\u662f,\u8fd9\u4e00\u7ed3\u679c\u5e76\u4e0d\u80fd\u8bf4\u660e\u6bcd\u4e73\u4e0d\u4f1a\u5f71\u54cd\u5a74\u513f\u5bf9\u8f6e\u72b6\u75c5\u6bd2\u75ab\u82d7\u7684\u514d\u75ab\u5e94\u7b54\uff61\u8fd9\u662f\u56e0\u4e3a\u8f6e\u72b6\u75c5\u6bd2\u75ab\u82d7\u5728\u80a0\u9053\u7684\u590d\u5236\u9700\u8981\u4e00\u5b9a\u7684\u65f6\u95f4,\u5373\u4f7f\u5728\u63a5\u79cd\u524d\u6ca1\u6709\u8fdb\u884c\u6bcd\u4e73\u5582\u517b,\u4f46\u662f,\u63a5\u79cd\u540e\u6bcd\u4e73\u540c\u6837\u4f1a\u6291\u5236\u8f6e\u72b6\u75c5\u6bd2\u7684\u590d\u5236\u4ece\u800c\u5f71\u54cd\u5176\u514d\u75ab\u5e94\u7b54\uff61<\/span><\/p>\n<p style=\"margin-top: 20px;margin-bottom: 10px;max-width: 100%;min-height: 1em;letter-spacing: 0.544px;white-space: normal;background-color: rgb(255, 255, 255);line-height: 1.75em;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 15px;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;font-family: \u5b8b\u4f53;box-sizing: border-box !important;overflow-wrap: break-word !important;\">4.\u5a74\u513f\u6297\u4f53\u6c34\u5e73\u4e0e\u8f6e\u72b6\u75c5\u6bd2\u75ab\u82d7\u514d\u75ab\u5e94\u7b54\u7684\u5173\u7cfb<\/span><\/strong><\/span><\/p>\n<p style=\"margin-top: 10px;margin-bottom: 10px;max-width: 100%;min-height: 1em;letter-spacing: 0.544px;white-space: normal;background-color: rgb(255, 255, 255);line-height: 1.75em;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;font-family: \u5b8b\u4f53;font-size: 14px;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u591a\u9879\u7814\u7a76\u8868\u660e,\u5a74\u513f\u63a5\u79cd\u75ab\u82d7\u524d\u7684\u8f6e\u72b6\u75c5\u6bd2\u7279\u5f02\u6027\u6297\u4f53\u6c34\u5e73\u4e0e\u8f6e\u72b6\u75c5\u6bd2\u75ab\u82d7\u63a5\u79cd\u540e\u7684\u514d\u75ab\u5e94\u7b54\u5448\u8d1f\u76f8\u5173\uff61Moon\u7b49<sup style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">[16]<\/sup>\u7814\u7a76\u53d1\u73b0,\u5a74\u513f\u514d\u524d\u8f6e\u72b6\u75c5\u6bd2\u7279\u5f02\u6027IgA\u548cIgG\u7684\u6c34\u5e73\u5747\u4e0e\u63a5\u79cd\u75ab\u82d7Rotarix\u00ae\u540e\u7684\u8840\u6e05\u5b66\u8f6c\u6362\u6548\u7387\u5448\u8d1f\u76f8\u5173\u5173\u7cfb\uff61Becker-Dreps\u7b49<sup style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">[3]<\/sup>\u5728\u4e94\u4ef7\u82d7Rotateq\u00ae\u7684\u7814\u7a76\u4e2d\u53d1\u73b0,\u514d\u75ab\u524d\u8840\u6e05IgA\u9633\u6027\u7684\u5a74\u513f\u63a5\u79cd\u8f6e\u72b6\u75c5\u6bd2\u75ab\u82d7\u540e\u7684\u8840\u6e05\u5b66\u8f6c\u6362\u7387\u4ec5\u4e3a30%,\u800c\u514d\u524d\u8840\u6e05IgA\u9634\u6027\u7684\u5a74\u513f\u7684\u8840\u6e05\u5b66\u8f6c\u6362\u7387\u5219\u9ad8\u8fbe80%,\u5dee\u5f02\u5177\u6709\u7edf\u8ba1\u5b66\u610f\u4e49(P=0.005)\uff61<\/span><\/p>\n<p style=\"margin-top: 10px;margin-bottom: 10px;max-width: 100%;min-height: 1em;letter-spacing: 0.544px;white-space: normal;background-color: rgb(255, 255, 255);line-height: 1.75em;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;font-family: \u5b8b\u4f53;font-size: 14px;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u540c\u6837\u7684,Chilengi\u7b49\u7814\u7a76\u53d1\u73b0\u8f6e\u72b6\u75c5\u6bd2\u7279\u5f02\u6027IgA\u6297\u4f53\u8840\u6e05\u9633\u6027\u7684\u5a74\u513f\u63a5\u79cd\u75ab\u82d7Rotarix\u00ae\u540e\u4ea7\u751f\u6297\u4f53\u7684\u6bd4\u4f8b\u76f8\u6bd4\u514d\u524dIgA\u6297\u4f53\u9634\u6027\u7684\u5a74\u513f\u4f4e,\u5e76\u4e14\u5dee\u5f02\u5177\u6709\u7edf\u8ba1\u5b66\u610f\u4e49(P=0.04)\uff61\u7531\u4e8e\u5a74\u513f\u57286\u4e2a\u6708\u4e4b\u524d\u611f\u67d3\u8f6e\u72b6\u75c5\u6bd2\u7684\u6982\u7387\u8f83\u4f4e,\u5a74\u513f\u8840\u6e05\u4e2d\u8f6e\u72b6\u75c5\u6bd2\u7279\u5f02\u6027\u6297\u4f53\u6765\u6e90\u4e8e\u6bcd\u6e90\u6297\u4f53<sup style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">[3,16,22]<\/sup>\uff61<\/span><\/p>\n<p style=\"margin-top: 10px;margin-bottom: 20px;max-width: 100%;min-height: 1em;letter-spacing: 0.544px;white-space: normal;background-color: rgb(255, 255, 255);line-height: 1.75em;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;font-family: \u5b8b\u4f53;font-size: 14px;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u540c\u65f6,\u7531\u4e8e\u53ea\u6709IgG\u6297\u4f53\u80fd\u591f\u901a\u8fc7\u80ce\u76d8\u4f20\u9012\u7ed9\u80ce\u513f,\u5a74\u513f\u8840\u6e05\u4e2dIgA\u6297\u4f53\u5219\u53ea\u80fd\u901a\u8fc7\u6bcd\u4e73\u83b7\u5f97\uff61\u56e0\u6b64,\u5c3d\u7ba1\u5728\u90e8\u5206\u7814\u7a76\u4e2d\u6539\u53d8\u6bcd\u4e73\u5582\u517b\u65b9\u5f0f\u4e0d\u80fd\u63d0\u9ad8\u8f6e\u72b6\u75c5\u6bd2\u75ab\u82d7\u7684\u514d\u75ab\u5e94\u7b54,\u6211\u4eec\u4e0d\u96be\u63a8\u6d4b,\u9ad8\u6ef4\u5ea6\u7684\u6bcd\u4e73\u6297\u4f53\u4f1a\u6291\u5236\u8f6e\u72b6\u75c5\u6bd2\u75ab\u82d7\u7684\u514d\u75ab\u5e94\u7b54,\u4ece\u800c\u5f71\u54cd\u5176\u6709\u6548\u6027\uff61<\/span><\/p>\n<p style=\"margin-top: 10px;margin-bottom: 10px;max-width: 100%;min-height: 1em;letter-spacing: 0.544px;white-space: normal;background-color: rgb(255, 255, 255);line-height: 1.75em;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><br  \/><\/p>\n<section class=\"\" style=\"max-width: 100%;letter-spacing: 0.544px;white-space: normal;background-color: rgb(255, 255, 255);border-width: 0px;border-style: none;border-color: initial;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<section  class=\"\"  font-size=\"14px\" style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<section style=\"margin-left: 1em;max-width: 100%;line-height: 1.4;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 15px;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span class=\"\" style=\"padding: 0.2em 0.5em;max-width: 100%;border-radius: 0.3em;color: rgb(255, 255, 255);text-align: inherit;background-color: rgb(102, 102, 102);font-family: inherit;font-weight: inherit;text-decoration: inherit;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u7ed3 \u8bed<\/span><\/strong><\/span><\/section>\n<section class=\"\" style=\"margin-top: -0.7em;max-width: 100%;border-width: 1px;border-style: solid;border-color: rgb(192, 200, 209);border-radius: 0.4em;font-size: 1em;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<section style=\"padding: 1.4em 1em 1em;max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<section style=\"max-width: 100%;font-size: 14px;font-weight: inherit;text-align: inherit;text-decoration: inherit;line-height: 30px;text-indent: 2em;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<p style=\"margin-top: 10px;margin-bottom: 10px;max-width: 100%;min-height: 1em;line-height: 2em;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;font-family: \u5b8b\u4f53;text-indent: 2em;text-decoration: inherit;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u7efc\u4e0a\u6240\u8ff0,\u9ad8\u6ef4\u5ea6\u7684\u6bcd\u6e90\u6297\u4f53\u4f1a\u6291\u5236\u5a74\u513f\u5bf9\u8f6e\u72b6\u75c5\u6bd2\u75ab\u82d7\u7684\u514d\u75ab\u5e94\u7b54\u6c34\u5e73,\u65e0\u8bba\u662f\u6bcd\u4eb2\u7684\u8840\u6e05\u6297\u4f53\u6c34\u5e73,\u8fd8\u662f\u6bcd\u4e73\u6297\u4f53\u6c34\u5e73,\u5747\u4e0e\u5a74\u513f\u5bf9\u8f6e\u72b6\u75c5\u6bd2\u75ab\u82d7\u7684\u514d\u75ab\u5e94\u7b54\u6c34\u5e73\u5448\u8d1f\u76f8\u5173\uff61\u5c3d\u7ba1\u5982\u6b64,\u6539\u53d8\u6bcd\u4e73\u5582\u517b\u65b9\u5f0f\u5e76\u4e0d\u80fd\u663e\u8457\u63d0\u9ad8\u8f6e\u72b6\u75c5\u6bd2\u75ab\u82d7\u7684\u514d\u75ab\u4fdd\u62a4\u6027\uff61<\/span><\/p>\n<p style=\"margin-top: 10px;margin-bottom: 10px;max-width: 100%;min-height: 1em;line-height: 2em;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;font-family: \u5b8b\u4f53;text-indent: 2em;text-decoration: inherit;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u968f\u7740\u5a74\u513f\u7684\u6210\u957f,\u6bcd\u6e90\u6297\u4f53\u6c34\u5e73\u4f1a\u4e0d\u65ad\u964d\u4f4e,\u9002\u5f53\u63a8\u8fdf\u8f6e\u72b6\u75c5\u6bd2\u75ab\u82d7\u7684\u63a5\u79cd\u65f6\u95f4\u53ef\u80fd\u53ef\u4ee5\u83b7\u5f97\u66f4\u597d\u7684\u514d\u75ab\u4fdd\u62a4\u6548\u679c,\u4f46\u662f,\u63a8\u8fdf\u63a5\u79cd\u4f1a\u589e\u52a0\u80a0\u5957\u53e0\u7684\u98ce\u9669,\u4e14\u4ece6\u4e2a\u6708\u5f00\u59cb,\u8f6e\u72b6\u75c5\u6bd2\u7684\u611f\u67d3\u7387\u663e\u8457\u4e0a\u5347,\u5fc5\u987b\u57286\u4e2a\u6708\u524d,\u5373\u6bcd\u6e90\u6297\u4f53\u6d88\u5931\u4e4b\u524d\u5b8c\u6210\u8f6e\u72b6\u75c5\u6bd2\u75ab\u82d7\u7684\u63a5\u79cd\uff61\u56e0\u6b64,\u63a8\u8fdf\u63a5\u79cd\u4e0d\u80fd\u4ece\u6839\u672c\u4e0a\u89e3\u51b3\u95ee\u9898,\u5f00\u53d1\u65b0\u578b\u7684\u975e\u590d\u5236\u578b\u8f6e\u72b6\u75c5\u6bd2\u75ab\u82d7,\u901a\u8fc7\u80a0\u9053\u5916\u514d\u75ab\u624d\u80fd\u4ece\u6839\u672c\u4e0a\u89e3\u51b3\u6bcd\u6e90\u6297\u4f53\u5bf9\u8f6e\u72b6\u75c5\u6bd2\u75ab\u82d7\u514d\u75ab\u5e94\u7b54\u7684\u6291\u5236\uff61<\/span><\/p>\n<p style=\"margin-top: 10px;margin-bottom: 10px;max-width: 100%;min-height: 1em;line-height: 2em;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;font-family: \u5b8b\u4f53;text-indent: 2em;text-decoration: inherit;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u540c\u65f6,\u76ee\u524d\u5173\u4e8e\u6bcd\u6e90\u6297\u4f53\u5bf9\u8f6e\u72b6\u75c5\u6bd2\u75ab\u82d7\u514d\u75ab\u5e94\u7b54\u7684\u5f71\u54cd\u7684\u7814\u7a76\u4e3b\u8981\u662f\u57fa\u4e8e\u4eba\u7fa4\u7684\u6297\u4f53\u6c34\u5e73\u8fdb\u884c\u5206\u6790,\u4e14\u591a\u4e3a\u56de\u987e\u6027\u7814\u7a76\uff61\u56e0\u6b64,\u6709\u5fc5\u8981\u8fdb\u4e00\u6b65\u901a\u8fc7\u52a8\u7269\u6a21\u578b\u7814\u7a76\u4e0d\u540c\u6765\u6e90\u7684\u6bcd\u6e90\u6297\u4f53\u5bf9\u8f6e\u72b6\u75c5\u6bd2\u75ab\u82d7\u514d\u75ab\u5e94\u7b54\u7684\u5f71\u54cd\u53ca\u5176\u673a\u5236,\u4ece\u800c\u4e3a\u63d0\u9ad8\u8f6e\u72b6\u75c5\u6bd2\u75ab\u82d7\u5728\u4f4e\u6536\u5165\u56fd\u5bb6\u7684\u4fdd\u62a4\u6027\u63d0\u4f9b\u66f4\u6709\u529b\u7684\u4f9d\u636e\uff61<\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><br  \/><\/p>\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<section  class=\"\"  font-size=\"14px\" style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"  \/><\/p>\n<section  style=\"max-width: 100%;display: inline-block;width: 676.992px;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<section  style=\"max-width: 100%;display: inline-block;color: rgb(107, 160, 172);font-size: 12px;line-height: 30px;width: 676.992px;background-color: rgb(226, 239, 243);box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<section style=\"padding-top: 10px;padding-left: 30px;max-width: 100%;display: inline-block;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<p style=\"max-width: 100%;min-height: 1em;display: inline-block;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><img class=\"\"    style=\"vertical-align: middle;box-sizing: border-box !important;overflow-wrap: break-word !important;width: 14px !important;visibility: visible !important;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2019\/05\/3-1558084768.png\" alt=\"\u6bcd\u6e90\u6297\u4f53\u5bf9\u8f6e\u72b6\u75c5\u6bd2\u75ab\u82d7\u6709\u6548\u6027\u7684\u5f71\u54cd\" title=\"\u6bcd\u6e90\u6297\u4f53\u5bf9\u8f6e\u72b6\u75c5\u6bd2\u75ab\u82d7\u6709\u6548\u6027\u7684\u5f71\u54cd\"  \/><\/p>\n<p style=\"padding-left: 5px;max-width: 100%;min-height: 1em;display: inline-block;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u5411\u4e0a\u6ed1\u52a8\u9605\u89c8<\/p>\n<\/section>\n<\/section>\n<section  style=\"max-width: 100%;display: inline-block;font-size: 14px;line-height: 30px;width: 676.992px;background-color: rgb(226, 239, 243);height: 200px;overflow-y: auto;text-align: center;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<section style=\"padding-right: 10px;padding-left: 10px;max-width: 100%;display: inline-block;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<p style=\"max-width: 100%;min-height: 1em;font-family: Calibri, sans-serif;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;font-family: \u5b8b\u4f53;font-size: 12px;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u53c2\u8003\u6587\u732e<\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;text-align: justify;font-family: Calibri, sans-serif;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;font-family: \u5b8b\u4f53;font-size: 12px;box-sizing: border-box !important;overflow-wrap: break-word !important;\">[1] Moon SS, Tate JE, Ray P, et al. Differential profiles and inhibitory effect on rotavirus vaccines of nonantibody components in breast milk from mothers in developing and developed countries [ J]. Pediatr Infect Dis J, 2013, 32(8): 863-870.&nbsp;<\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;text-align: justify;font-family: Calibri, sans-serif;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;font-family: \u5b8b\u4f53;font-size: 12px;box-sizing: border-box !important;overflow-wrap: break-word !important;\">[2] Appaiahgari MB, Glass R, Singh S, et al. Transplacental rotavirus IgG interferes with immune response to live oral rotavirus vaccine ORV-116E in Indian infants[J]. Vaccine, 2014, 32(6): 651-656.<\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;text-align: justify;font-family: Calibri, sans-serif;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 12px;font-family: \u5b8b\u4f53;box-sizing: border-box !important;overflow-wrap: break-word !important;\">[3]Becker-Dreps S, Vilchez S, Velasquez D, et al. Rotavirus-specificIgG antibodies from mothers\u2032serum may inhibit infant immune responses to the pentavalent rotavirus vaccine[J]. Pediatr Infect Dis J, 2015, 34 ( 1 ): 115-116.&nbsp;<\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;text-align: justify;font-family: Calibri, sans-serif;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;font-family: \u5b8b\u4f53;font-size: 12px;box-sizing: border-box !important;overflow-wrap: break-word !important;\">[4] Patel M, Steele AD, Parashar UD. Influence of oral polio vaccines on performance of the monovalent and pentavalent rotavirus vaccines[J]. Vaccine, 2012, 30 Suppl 1: A30-A35.<\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;text-align: justify;font-family: Calibri, sans-serif;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;font-family: \u5b8b\u4f53;font-size: 12px;box-sizing: border-box !important;overflow-wrap: break-word !important;\">[5] Zaman K, Sack DA, Yunus M, et al. Successful co-administration of a human rotavirus and oral poliovirus vaccines in Bangladeshi in fants in a 2-dose schedule at 12 and 16 weeks of age[J]. Vaccine, 2009, 27(9): 1333-1339.<\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;text-align: justify;font-family: Calibri, sans-serif;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;font-family: \u5b8b\u4f53;font-size: 12px;box-sizing: border-box !important;overflow-wrap: break-word !important;\">[6] Emperador DM, Velasquez DE, Estivariz CF, et al. Interference of monovalent, bivalent, and trivalent oral poliovirus vaccines on monovalent rotavirus vaccine immunogenicity in rural Bangladesh&nbsp;&nbsp;[J]. Clin Infect Dis, 2016, 62(2): 150-156.&nbsp;<\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;text-align: justify;font-family: Calibri, sans-serif;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;font-family: \u5b8b\u4f53;font-size: 12px;box-sizing: border-box !important;overflow-wrap: break-word !important;\">[7] Rennels MB. Influence of breast-feeding and oral poliovirus vac-<\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;text-align: justify;font-family: Calibri, sans-serif;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;font-family: \u5b8b\u4f53;font-size: 12px;box-sizing: border-box !important;overflow-wrap: break-word !important;\">cine on the immunogenicity and efficacy of rotavirus vaccines[J]. J Infect Dis, 1996, 174 Suppl 1: S107-S111.<\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;text-align: justify;font-family: Calibri, sans-serif;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;font-family: \u5b8b\u4f53;font-size: 12px;box-sizing: border-box !important;overflow-wrap: break-word !important;\">[8] Petri WA Jr, Miller M, Binder HJ, et al. Enteric infections, diarrhea, and their impact on function and development[J]. 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Philos Trans R Soc Lond B Biol Sci, 2015, 370(1671). pii: 140-141.<\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;text-align: justify;font-family: Calibri, sans-serif;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;font-family: \u5b8b\u4f53;font-size: 12px;box-sizing: border-box !important;overflow-wrap: break-word !important;\">[11] Gilmartin AA, Petri WA Jr. Exploring the role of environmental enteropathy in malnutrition, infant development and oral vaccine response[J]. Philos Trans R Soc Lond B Biol Sci, 2015, 370&nbsp;&nbsp;(1671). pii: 20140143.<\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;text-align: justify;font-family: Calibri, sans-serif;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;font-family: \u5b8b\u4f53;font-size: 12px;box-sizing: border-box !important;overflow-wrap: break-word !important;\">&nbsp;[12] Nakaya HI, Bruna-Romero O. Is the gut microbiome key to modulating vaccine efficacy? [J]. Expert Rev Vaccines, 2015, 14(6): 777-779.<\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;text-align: justify;font-family: Calibri, sans-serif;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;font-family: \u5b8b\u4f53;font-size: 12px;box-sizing: border-box !important;overflow-wrap: break-word !important;\">&nbsp;[13] Naylor C, Lu M, Haque R, et al. Environmental enteropathy, oral vaccine failure and growth faltering in infants in Bangladesh[J]. EBioMedicine, 2015, 2(11): 1759-1766.&nbsp;<\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;text-align: justify;font-family: Calibri, sans-serif;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;font-family: \u5b8b\u4f53;font-size: 12px;box-sizing: border-box !important;overflow-wrap: break-word !important;\">[14] Nordgren J, Sharma S, Bucardo F, et al. Both Lewis and secretor status mediate susceptibility to rotavirus infections in a rotavirus genotype-dependent manner[J]. Clin Infect Dis, 2014, 59(11): 1567-1573.&nbsp;<\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;text-align: justify;font-family: Calibri, sans-serif;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;font-family: \u5b8b\u4f53;font-size: 12px;box-sizing: border-box !important;overflow-wrap: break-word !important;\">[15] Coulson BS. Expanding diversity of glycan receptor usage by rotaviruses[J]. Curr Opin Virol, 2015, 15: 90-96.<\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;text-align: justify;font-family: Calibri, sans-serif;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;font-family: \u5b8b\u4f53;font-size: 12px;box-sizing: border-box !important;overflow-wrap: break-word !important;\">[16] Moon SS, Groome MJ, Velasquez DE, et al. Prevaccination rotavirus serum IgG and IgA are associated with lower immunogenicity of live, oral human rotavirus vaccine in South African infants[J]. Clin Infect Dis, 2016, 62 (2): 157-165.<\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;text-align: justify;font-family: Calibri, sans-serif;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;font-family: \u5b8b\u4f53;font-size: 12px;box-sizing: border-box !important;overflow-wrap: break-word !important;\">[17] Vesikari T, Prymula R, Schuster V, et al. Efficacy and immunogenicity of live-attenuated human rotavirus vaccine in breast-fed and formula-fed European infants[J]. Pediatr Infect Dis, 012, 31(5): 509-513.&nbsp;<\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;text-align: justify;font-family: Calibri, sans-serif;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;font-family: \u5b8b\u4f53;font-size: 12px;box-sizing: border-box !important;overflow-wrap: break-word !important;\">[18] Goveia MG, DiNubile MJ, Dallas MJ, et al. Efficacy of pentavalent human-bovine (WC3) reassortant rotavirus vaccine based on breastfeeding frequency[J]. Pediatr Infect Dis J, 2008, 27(7): 656-658.<\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;text-align: justify;font-family: Calibri, sans-serif;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;font-family: \u5b8b\u4f53;font-size: 12px;box-sizing: border-box !important;overflow-wrap: break-word !important;\">[19] Adlhoch C, Hoehne M, Littmann M, et al. Rotavirus vaccine effectiveness and case-control study on risk factors for breakthrough infections in Germany, 2010-2011 [ J]. Pediatr Infect Dis J,2013, 32 ( 2 ): 82-89.&nbsp;<\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"  \/><\/p>\n<\/section>\n<\/section>\n<\/section>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"  \/><\/p>\n<\/section>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 12px;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u6587\u7ae0\u6765\u6e90\uff1a<span style=\"max-width: 100%;font-family: \u5b8b\u4f53;box-sizing: border-box !important;overflow-wrap: break-word 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