{"id":11096,"date":"2018-06-12T01:00:00","date_gmt":"2018-07-27T09:52:42","guid":{"rendered":"http:\/\/www.05921.net\/index.php\/2018\/07\/27\/%e8%81%8a%e4%b8%80%e8%81%8a%e5%b9%b2%e7%bb%86%e8%83%9e%e6%b2%bb%e7%96%97%e7%9c%bc%e7%96%be\/"},"modified":"2018-07-27T17:52:44","modified_gmt":"2018-07-27T09:52:44","slug":"%e8%81%8a%e4%b8%80%e8%81%8a%e5%b9%b2%e7%bb%86%e8%83%9e%e6%b2%bb%e7%96%97%e7%9c%bc%e7%96%be","status":"publish","type":"post","link":"https:\/\/www.05921.net\/index.php\/11096\/","title":{"rendered":"\u804a\u4e00\u804a\u5e72\u7ec6\u80de\u6cbb\u7597\u773c\u75be"},"content":{"rendered":"<div class=\"bpp-post-content\">\n<section style=\"max-width: 100%;color: rgb(51, 51, 51);box-sizing: border-box !important;word-wrap: break-word !important;\">\n<section class=\"\" style=\"margin: auto;max-width: 100%;box-sizing: border-box;border-color: rgb(249, 110, 87);width: 3em;text-align: center;color: rgb(255, 255, 255);font-family: inherit;font-size: 1em;font-weight: 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100%;box-sizing: border-box;width: 0.6em;height: 0.6em;display: inline-block;vertical-align: top;background-color: rgb(160, 160, 160);word-wrap: break-word !important;\"><\/span><\/section>\n<section style=\"margin: auto;max-width: 100%;box-sizing: border-box;width: 2.5em;text-align: right;line-height: 0;word-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<p style=\"margin-top: 15px;margin-bottom: 15px;max-width: 100%;min-height: 1em;white-space: normal;text-indent: 2em;line-height: 1.75em;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 15px;box-sizing: border-box !important;word-wrap: break-word 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!important;\"><\/span><span style=\"max-width: 100%;font-size: 15px;box-sizing: border-box !important;word-wrap: break-word !important;\">\u76ee\u524d\uff0c\u5e72\u7ec6\u80de\u5728\u773c\u79d1\u75be\u75c5\u7684\u5e94\u7528\u4e3b\u8981\u96c6\u4e2d\u4e8e\u4ee5\u4e0b\u51e0\u4e2a\u65b9\u9762\uff1a<\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;white-space: normal;box-sizing: border-box !important;word-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/p>\n<section style=\"margin-top: 5px;max-width: 100%;box-sizing: border-box;letter-spacing: 0.544px;color: rgb(62, 62, 62);font-size: 16px;font-family: \u5fae\u8f6f\u96c5\u9ed1;font-weight: bold;line-height: 25.6px;text-align: center;background-color: rgb(255, 255, 255);word-wrap: break-word !important;overflow-wrap: break-word !important;\">\n<section style=\"padding-top: 4px;padding-right: 10px;padding-bottom: 4px;max-width: 100%;box-sizing: border-box;border-top-width: 2px;border-top-style: solid;border-bottom-width: 2px;border-bottom-style: solid;display: inline-block;border-left-color: rgb(234, 234, 237);border-right-color: rgb(234, 234, 237);word-wrap: break-word !important;overflow-wrap: break-word !important;\">\n<section style=\"margin-top: -8px;max-width: 100%;box-sizing: border-box;white-space: normal;display: inline-block;float: left;width: 60px;background-color: rgb(254, 254, 254);word-wrap: break-word !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;color: rgb(63, 63, 63);font-size: 42px;box-sizing: border-box !important;word-wrap: break-word !important;overflow-wrap: break-word !important;\"><em style=\"max-width: 100%;list-style-type: none;-webkit-padding-start: 0px;-webkit-margin-before: 0px;-webkit-margin-after: 0px;-webkit-margin-start: 0px;-webkit-margin-end: 0px;box-sizing: border-box !important;word-wrap: break-word !important;overflow-wrap: break-word !important;\">1<\/em><\/span><\/section>\n<p><span style=\"max-width: 100%;white-space: pre-wrap;box-sizing: border-box !important;word-wrap: break-word !important;\">\u5e72\u7ec6\u80de\u4e0e\u89d2\u819c\u635f\u4f24<\/span><\/section>\n<\/section>\n<p style=\"margin-top: 15px;margin-bottom: 15px;max-width: 100%;min-height: 1em;text-indent: 2em;line-height: 1.75em;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 15px;box-sizing: border-box !important;word-wrap: break-word !important;\">\u89d2\u819c\u7f18\u5e72\u7ec6\u80de\uff08limbal stem cell\uff09\uff1a\u4e3b\u8981\u5b58\u5728\u4e8e\u89d2\u819c\u7f18\uff08Limbus\uff09\u7b49\u591a\u4e2a\u89d2\u819c\u90e8\u4f4d\u7684\u4e00\u79cd\u5e72\u7ec6\u80de[1]\uff1b\u4e3b\u8981\u7279\u5f81\u662f\u9ad8\u8868\u8fbeP63\uff0c\u4f4e\u8868\u8fbeCD71[2]\u3002\u76ee\u524d\u4e3b\u8981\u7528\u4e8e\u6cbb\u7597\u773c\u5916\u4f24\uff08\u5316\u5b66\u7269\u8d28\u3001\u70e7\u4f24\u7b49\uff09\u5bfc\u81f4\u7684\u89d2\u819c\u635f\u4f24\uff1b\u89d2\u819c\u7f18\u5e72\u7ec6\u80de\u7f3a\u9677\uff08LSCD\uff09\uff1b\u89d2\u819c\u6591\u75d5\u7b49\u5bfc\u81f4\u7684\u89d2\u819c\u6df7\u6d4a\u6216\u53d8\u767d\u7b49\u75be\u75c5\u3002<\/span><\/p>\n<p style=\"margin-top: 15px;margin-bottom: 15px;max-width: 100%;min-height: 1em;text-indent: 2em;line-height: 1.75em;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 15px;text-indent: 2em;font-family: inherit;text-decoration: inherit;box-sizing: border-box !important;word-wrap: break-word !important;\">\u81ea\u4f53\u89d2\u819c\u7f18\u5e72\u7ec6\u80de\u79fb\u690d\u5df2\u6210\u4e3a\u4e00\u79cd\u6210\u719f\u7684\u624b\u672f\u65b9\u6cd5\uff0c\u5355\u773c\u89d2\u819c\u7f18\u5e72\u7ec6\u80de\u7f3a\u9677\u60a3\u8005\u548c\u53cc\u773c\u89d2\u819c\u7f18\u5e72\u7ec6\u80de\u8f7b\u5fae\u7f3a\u9677\u60a3\u8005\u53ef\u4ee5\u5c06\u81ea\u4f53\u89d2\u819c\u7f18\u5e72\u7ec6\u80de\u6216\u5176\u4ed6\u90e8\u4f4d\uff08\u53e3\u8154\u9ecf\u819c\u7b49\uff09\u57f9\u517b\u540e\u8fdb\u884c\u79fb\u690d\uff0c\u8fbe\u5230\u91cd\u5efa\u773c\u8868\u3001\u6062\u590d\u89c6\u529b\u7684\u76ee\u7684\uff0c\u8fd9\u4e0d\u9700\u8981\u514d\u75ab\u6291\u5236\u5242\u4f46\u6709\u53ef\u80fd\u5bf9\u53e6\u4e00\u53ea\u6b63\u5e38\u773c\u775b\u9020\u6210\u4f24\u5bb3\uff1b\u800c\u5bf9\u4e8e\u53cc\u773c\u89d2\u819c\u7f18\u5e72\u7ec6\u80de\u4e25\u91cd\u7f3a\u9677\u60a3\u8005\uff0c\u7531\u4e8e\u53ea\u80fd\u7528\u5f02\u4f53\u89d2\u819c\u7f18\u5e72\u7ec6\u80de\u57f9\u517b\u540e\u79fb\u690d\uff0c\u5c1a\u9700\u8981\u89e3\u51b3\u514d\u75ab\u6392\u65a5\u3001\u514d\u75ab\u6291\u5236\u5242\u4f7f\u7528\u7684\u95ee\u9898\u3002<\/span><\/p>\n<p style=\"margin-top: 15px;margin-bottom: 15px;max-width: 100%;min-height: 1em;line-height: 1.75em;text-indent: 0em;text-align: center;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 15px;text-indent: 2em;font-family: inherit;text-decoration: inherit;box-sizing: border-box !important;word-wrap: break-word !important;\"><img class=\"\"       style=\"white-space: normal;box-sizing: border-box !important;word-wrap: break-word !important;width: 376px !important;visibility: visible !important;\" width=\"376px\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/07\/beepress4-1532685163.jpeg\" alt=\"\u804a\u4e00\u804a\u5e72\u7ec6\u80de\u6cbb\u7597\u773c\u75be\" title=\"\u804a\u4e00\u804a\u5e72\u7ec6\u80de\u6cbb\u7597\u773c\u75be\"  \/><\/span><\/p>\n<p style=\"margin-top: 15px;margin-bottom: 15px;max-width: 100%;min-height: 1em;text-indent: 2em;line-height: 1.75em;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 15px;box-sizing: border-box !important;word-wrap: break-word !important;\">\u5173\u4e8e\u89d2\u819c\u635f\u4f24\u6848\u4f8b\uff0c\u6b65\u6b65\u8bb2\u4e24\u7bc7\u6587\u732e\u30022014\u5e747\u6708\uff0c\u4e2d\u5c71\u5927\u5b66\u773c\u79d1\u5b66\u56e2\u961f\u4e0e\u7f8e\u56fd\u7814\u7a76\u4eba\u5458\u5728nature\u6742\u5fd7\u53d1\u8868\u7684\u4e00\u7bc7\u6587\u7ae0\u300aWNT7A and PAX6 definecorneal epithelium homeostasis and pathogenesis\u300b[3]\u3002\u8be5\u7814\u7a76\u6210\u679c\u8bc1\u5b9e\u4e86\u8c03\u63a7\u89d2\u819c\u7f18\u5e72\u7ec6\u80de\u5206\u5316\u7684\u5173\u952e\u56e0\u5b50WNT7A\u548cPAX6\u5728\u89d2\u819c\u8c31\u7cfb\u4e13\u5411\u5206\u5316\u4e2d\u8d77\u7740\u91cd\u8981\u7684\u4f5c\u7528\uff0c\u9996\u6b21\u5c06\u76ae\u80a4\u5e72\u7ec6\u80de\u8bf1\u5bfc\u5206\u5316\u4e3a\u89d2\u819c\u7f18\u5e72\u7ec6\u80de\uff0c\u5e76\u6210\u529f\u4fee\u590d\u89d2\u819c\u529f\u80fd\uff0c\u4e3a\u6cbb\u7597\u89d2\u819c\u75be\u75c5\u63d0\u4f9b\u65b0\u7b56\u7565\u3002\u4e3a\u4fee\u590d\u548c\u518d\u751f\u89d2\u819c\u8868\u9762\uff0c\u6cbb\u7597\u89d2\u819c\u7f18\u5e72\u7ec6\u80de\u7f3a\u9677\u60a3\u8005\u63d0\u4f9b\u4e86\u4e00\u4e2a\u6f5c\u5728\u7684\u8d44\u6e90\u3002<\/span><\/p>\n<p style=\"margin-top: 15px;margin-bottom: 15px;max-width: 100%;min-height: 1em;text-indent: 2em;line-height: 1.75em;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 15px;box-sizing: border-box !important;word-wrap: break-word !important;\">\u57282010\u5e74\uff0cN Engl J&nbsp;\u6742\u5fd7\u53d1\u8868\u4e86\u4e00\u7bc7\u6587\u7ae0\u300aLimbal Stem-Cell Therapy and Long-Term Corneal Regeneration\u300b[4]\uff0c\u610f\u5927\u5229\u7814\u7a76\u4eba\u5458\u7528\u75c5\u4eba\u81ea\u8eab\u89d2\u819c\u7f18\u5e72\u7ec6\u80de\u6cbb\u7597\u89d2\u819c\u635f\u4f24\u3002\u5728\u60a3\u8005\u7684\u773c\u767d\u548c\u89d2\u819c\u95f4\u7684\u5f02\u7ec4\u7ec7\u8fb9\u7f18\u63d0\u53d6\u5e72\u7ec6\u80de\uff0c\u5f85\u5176\u53d1\u80b2\u4e3a\u7ea4\u7ef4\u7ec4\u7ec7\u540e\uff0c\u518d\u690d\u5165\u60a3\u8005\u7684\u773c\u775b\u53d7\u635f\u90e8\u4f4d\u3002112\u540d\u88ab\u5316\u5b66\u707c\u4f24\u800c\u5bfc\u81f4\u5931\u660e\u7684\u60a3\u8005\u8fdb\u884c\u6cbb\u7597\uff0c\u7ed3\u679c\u8d85\u8fc7\u56db\u5206\u4e4b\u4e09\u7684\u60a3\u8005\u6062\u590d\u4e86\u89c6\u529b\u3002\u8be5\u6280\u672f\u4e00\u6b21\u79fb\u690d\u6210\u529f\u7387\u4e3a68.2%\uff0c\u4e8c\u6b21\u79fb\u690d\u6210\u529f\u7387\u4e3a75%\uff0c\u8fd8\u670913.1%\u60a3\u8005\u7684\u89c6\u529b\u83b7\u5f97\u90e8\u5206\u6539\u5584\uff0c\u4ec5\u670910.3%\u7684\u60a3\u8005\u89c6\u529b\u65e0\u6cd5\u83b7\u5f97\u6539\u5584\u3002\uff08\u5982\u88681.\uff09\u8be5\u7814\u7a76\u53d1\u73b0P63\u9633\u6027\u7ec6\u80de\u6bd4\u4f8b\u5bf9\u4e8e\u6cbb\u7597\u6210\u529f\u5f88\u91cd\u8981\u3002<\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;word-wrap: break-word !important;\"><img class=\"\"      style=\"box-sizing: border-box !important;word-wrap: break-word !important;width: auto !important;visibility: visible !important;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/07\/beepress1-1532685163.jpg\" alt=\"\u804a\u4e00\u804a\u5e72\u7ec6\u80de\u6cbb\u7597\u773c\u75be\" title=\"\u804a\u4e00\u804a\u5e72\u7ec6\u80de\u6cbb\u7597\u773c\u75be\"  \/><\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;white-space: normal;font-size: 17px;color: rgb(69, 72, 73);text-align: center;line-height: 1.75em;word-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/p>\n<section style=\"margin-top: 5px;max-width: 100%;box-sizing: border-box;letter-spacing: 0.544px;white-space: normal;color: rgb(62, 62, 62);font-size: 16px;font-family: \u5fae\u8f6f\u96c5\u9ed1;font-weight: bold;line-height: 25.6px;text-align: center;background-color: rgb(255, 255, 255);word-wrap: break-word !important;overflow-wrap: break-word !important;\">\n<section style=\"padding-top: 4px;padding-right: 10px;padding-bottom: 4px;max-width: 100%;box-sizing: border-box;border-top-width: 2px;border-top-style: solid;border-bottom-width: 2px;border-bottom-style: solid;display: inline-block;border-left-color: rgb(234, 234, 237);border-right-color: rgb(234, 234, 237);word-wrap: break-word !important;overflow-wrap: break-word !important;\">\n<section style=\"margin-top: -8px;max-width: 100%;box-sizing: border-box;display: inline-block;float: left;width: 60px;background-color: rgb(254, 254, 254);word-wrap: break-word !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;color: rgb(63, 63, 63);font-size: 42px;box-sizing: border-box !important;word-wrap: break-word !important;overflow-wrap: break-word !important;\"><em style=\"max-width: 100%;list-style-type: none;-webkit-padding-start: 0px;-webkit-margin-before: 0px;-webkit-margin-after: 0px;-webkit-margin-start: 0px;-webkit-margin-end: 0px;box-sizing: border-box !important;word-wrap: break-word !important;overflow-wrap: break-word !important;\">2<\/em><\/span><\/section>\n<p><span style=\"max-width: 100%;white-space: pre-wrap;box-sizing: border-box !important;word-wrap: break-word !important;\">\u5e72\u7ec6\u80de\u4e0e\u89c6\u7f51\u819c\u75be\u75c5<\/span><\/section>\n<\/section>\n<p style=\"margin-top: 15px;margin-bottom: 15px;max-width: 100%;min-height: 1em;text-indent: 2em;line-height: 1.75em;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 15px;box-sizing: border-box !important;word-wrap: break-word !important;\">\u89c6\u7f51\u819c\u75be\u75c5\u5728\u4e34\u5e8a\u4e0a\u5f88\u5e38\u89c1\uff0c\u5728\u8fd9\u91cc\u6b65\u6b65\u4e3b\u8981\u8bb2\u5e72\u6027\u5e74\u9f84\u76f8\u5173\u6027\u9ec4\u6591\u53d8\u6027\uff08Dry age-related macular degeneration\uff0cAMD\uff09\u548c\u5c11\u5e74\u578b\u9ec4\u6591\u8425\u517b\u4e0d\u826f\uff08Stargardt\u75c5\uff09\u3002\u8fd9\u4e24\u79cd\u75be\u75c5\u90fd\u4e0e\u89c6\u7f51\u819c\u8272\u7d20\u4e0a\u76ae\u7ec6\u80de\uff08RPE\uff09\u9000\u884c\u6027\u53d8\u5316\u76f8\u5173\u3002\u524d\u8005\u4e3b\u8981\u7d2f\u53ca\u8001\u5e74\u4eba\uff0c\u540e\u8005\u5219\u662f\u4e00\u79cd\u901a\u5e38\u5728\u513f\u7ae5\u671f\u53d1\u75c5\u7684\u9057\u4f20\u6027\u75be\u75c5\u3002\u8fd9\u4e24\u79cd\u75be\u75c5\u5747\u53ef\u5f15\u8d77\u89c6\u7f51\u819c\u8272\u7d20\u4e0a\u76ae\uff08RPE\uff09\u529f\u80fd\u635f\u5bb3\uff0c\u4ece\u800c\u5bfc\u81f4\u5931\u660e\u3002\u89c6\u7f51\u819c\u8272\u7d20\u4e0a\u76ae\u7ec6\u80de\uff08retinal pigment epithelium\uff09\uff0c\u662f\u7531\u5355\u5c42\u8272\u7d20\u4e0a\u76ae\u7ec6\u80de\u6240\u6784\u6210\uff0c\u6392\u5217\u5341\u5206\u89c4\u5219\u3002\u7ec6\u80de\u5448\u591a\u89d2\u5f62\u3002\u4e3b\u8981\u7279\u5f81\u662fZO-1\uff0cbestrophin , MiTF\u7b49\u6807\u5fd7\u7269\u5448\u9633\u6027; OCT4, NANOG, and SOX2\u7b49\u6807\u5fd7\u7269\u5448\u9634\u6027\u3002<\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;text-align: center;box-sizing: border-box !important;word-wrap: break-word !important;\"><img class=\"\"       style=\"box-sizing: border-box !important;word-wrap: break-word !important;width: auto !important;visibility: visible !important;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/07\/beepress6-1532685163.jpeg\" alt=\"\u804a\u4e00\u804a\u5e72\u7ec6\u80de\u6cbb\u7597\u773c\u75be\" title=\"\u804a\u4e00\u804a\u5e72\u7ec6\u80de\u6cbb\u7597\u773c\u75be\"  \/><\/p>\n<p style=\"margin-top: 15px;margin-bottom: 15px;max-width: 100%;min-height: 1em;text-indent: 2em;line-height: 1.75em;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 15px;box-sizing: border-box !important;word-wrap: break-word !important;\">2010\u5e74\uff0c\u7f8e\u56fdACT\u516c\u53f8(advanced cell technology)\u83b7\u5f97FDA\u8bb8\u53ef\uff0c\u5229\u7528\u80da\u80ce\u5e72\u7ec6\u80de\u884d\u751f\u7684\u89c6\u7f51\u819c\u8272\u7d20\u4e0a\u76ae\u7ec6\u80de\uff08RPE)\u5bf9\u6cbb\u7597\u4e24\u79cd\u9000\u884c\u6027\u773c\u75be\u75c5\uff1a\u5e72\u6027\u5e74\u9f84\u76f8\u5173\u6027\u9ec4\u6591\u53d8\u6027\uff08Dry age-relatedmacular degeneration\uff0cAMD\uff09\u548c\u5c11\u5e74\u578b\u9ec4\u6591\u8425\u517b\u4e0d\u826f\uff08Stargardt\u75c5\uff09\u3002\u8fd9\u662fFDA\u6279\u51c6\u7684\u6d89\u53ca\u5230\u6e90\u81ea\u4eba\u7c7b\u80da\u80ce\u5e72\uff08hES\uff09\u7ec6\u80de\u7684\u7b2c\u4e8c\u9879\u4e34\u5e8a\u8bd5\u9a8c\u30022012\u5e74\uff0c\u8be5\u7814\u7a76\u673a\u6784\u5728\u300a\u67f3\u53f6\u5200\u300b\uff08The Lancet\uff09\u6742\u5fd7\u53d1\u8868\u4e86\u4e00\u7bc7\u6587\u7ae0\u300aEmbryonic stem cell trials for macular degeneration: a preliminaryreport\u300b[5]\uff0c\u7f8e\u56fd\u7814\u7a76\u4eba\u5458\u5229\u7528\u4eba\u7c7b\u80da\u80ce\u5e72\u7ec6\u80de(hESC)\u6cbb\u7597\u4e86\u4e24\u540d\u60a3\u6709\u4e0d\u540c\u9000\u5316\u6027\u773c\u75be\u75c5\u7684\u60a3\u8005\uff0c\u521d\u671f\u6570\u636e\u8868\u660ehESC\u6cbb\u7597\u4e0d\u4ec5\u5b89\u5168\uff0c\u4e14\u663e\u793a\u51fa\u4e86\u4e00\u4e9b\u6cbb\u7597\u6548\u529b\u3002\u4ed6\u4eec\u5c06hESCs\u8bf1\u5bfc\u751f\u6210\u4e86\u65e9\u671f\u9aa8\u7ec6\u80de\u548c\u795e\u7ecf\u7ec4\u7ec7\u7ec6\u80de\uff0c\u968f\u540e\u8fd9\u4e9b\u7ec6\u80de\u5206\u5316\u5f62\u6210\u4e86\u89c6\u7f51\u819c\u4e0a\u76ae\u7ec6\u80de\uff0c\u5176\u7eaf\u5ea6\u8d85\u8fc799%\u3002\u7814\u7a76\u4eba\u5458\u5c06\u5927\u7ea65\u4e07\u4e2a\u5206\u79bb\u51fa\u6765\u7684\u89c6\u7f51\u819c\u4e0a\u76ae\u7ec6\u80de\u6ce8\u5165\u5230\u4e24\u540d\u60a3\u8005\u7684\u89c6\u7f51\u819c\u4e0b\uff0c\u5176\u4e2d\u4e00\u540d\u8001\u5e74\u5973\u60a3\u8005\u5728\u517670\u591a\u5c81\u65f6\u60a3\u4e0a\u4e86\u5e72\u6027\u5e74\u9f84\u76f8\u5173\u6027\u9ec4\u6591\u53d8\u6027\uff0c\u800c\u53e6\u4e00\u540d\u4e2d\u5e74\u5973\u60a3\u8005\u5219\u60a3\u6709Stargardt\u75c5\uff0c\u56e0\u800c\u5bfc\u81f4\u4e86\u4e8c\u8005\u5931\u660e\u30024\u4e2a\u6708\u540e\uff0c\u7814\u7a76\u4eba\u5458\u53d1\u73b0RPE\u5df2\u88ab\u6ce8\u5165\u7684\u89c6\u7f51\u819c\u4e0a\u76ae\u7ec6\u80de\u5b8c\u5168\u53d6\u4ee3\uff0c\u6570\u636e\u8bc1\u5b9e\u6ce8\u5165\u7684\u7ec6\u80de\u5b58\u6d3b\u4e86\u4e0b\u6765\uff0c\u5e76\u5f88\u5927\u7a0b\u5ea6\u4e0a\u6539\u5584\u4e86\u5979\u4eec\u7684\u89c6\u529b\u3002\uff08\u5982\u88682.\uff09<\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;word-wrap: break-word !important;\"><img class=\"\"          style=\"box-sizing: border-box !important;word-wrap: break-word !important;width: auto !important;visibility: visible !important;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/07\/beepress1-1532685163-1.jpeg\" alt=\"\u804a\u4e00\u804a\u5e72\u7ec6\u80de\u6cbb\u7597\u773c\u75be\" title=\"\u804a\u4e00\u804a\u5e72\u7ec6\u80de\u6cbb\u7597\u773c\u75be\"  \/><\/p>\n<section style=\"margin-right: auto;margin-bottom: 4px;margin-left: auto;max-width: 100%;box-sizing: border-box;white-space: normal;font-size: 21.6px;line-height: 0;width: 2.5em;text-align: right;word-wrap: break-word !important;\"><br  style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/section>\n<p style=\"margin-right: auto;margin-bottom: 4px;margin-left: auto;max-width: 100%;box-sizing: border-box;min-height: 1em;white-space: normal;font-size: 21.6px;list-style-type: none;-webkit-padding-start: 0px;-webkit-margin-before: 0px;-webkit-margin-after: 0px;line-height: 0;width: 2.5em;text-align: right;word-wrap: break-word !important;\"><br  style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/p>\n<p style=\"margin-right: auto;margin-bottom: 4px;margin-left: auto;max-width: 100%;box-sizing: border-box;min-height: 1em;white-space: normal;font-size: 21.6px;list-style-type: none;-webkit-padding-start: 0px;-webkit-margin-before: 0px;-webkit-margin-after: 0px;line-height: 0;width: 2.5em;text-align: right;word-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/p>\n<section style=\"margin-top: 5px;max-width: 100%;box-sizing: border-box;letter-spacing: 0.544px;color: rgb(62, 62, 62);font-size: 16px;font-family: \u5fae\u8f6f\u96c5\u9ed1;font-weight: bold;line-height: 25.6px;text-align: center;background-color: rgb(255, 255, 255);word-wrap: break-word !important;overflow-wrap: break-word !important;\">\n<section style=\"padding-top: 4px;padding-right: 10px;padding-bottom: 4px;max-width: 100%;box-sizing: border-box;border-top-width: 2px;border-top-style: solid;border-bottom-width: 2px;border-bottom-style: solid;display: inline-block;border-left-color: rgb(234, 234, 237);border-right-color: rgb(234, 234, 237);word-wrap: break-word !important;overflow-wrap: break-word !important;\">\n<section style=\"margin-top: -8px;max-width: 100%;box-sizing: border-box;white-space: normal;display: inline-block;float: left;width: 60px;background-color: rgb(254, 254, 254);word-wrap: break-word !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;color: rgb(63, 63, 63);font-size: 42px;box-sizing: border-box !important;word-wrap: break-word !important;overflow-wrap: break-word !important;\"><em style=\"max-width: 100%;list-style-type: none;-webkit-padding-start: 0px;-webkit-margin-before: 0px;-webkit-margin-after: 0px;-webkit-margin-start: 0px;-webkit-margin-end: 0px;box-sizing: border-box !important;word-wrap: break-word !important;overflow-wrap: break-word !important;\">3<\/em><\/span><\/section>\n<p><span style=\"max-width: 100%;white-space: pre-wrap;box-sizing: border-box !important;word-wrap: break-word !important;\">\u5e72\u7ec6\u80de\u4e0e\u5176\u4ed6\u773c\u79d1\u75be\u75c5<\/span><\/section>\n<\/section>\n<p style=\"margin-top: 15px;margin-bottom: 15px;max-width: 100%;min-height: 1em;line-height: 1.75em;text-indent: 2em;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 15px;box-sizing: border-box !important;word-wrap: break-word !important;\">\u9752\u5149\u773c\u4f5c\u4e3a\u89c6\u7f51\u819c\u795e\u7ecf\u8282\u7ec6\u80de\u8fdb\u884c\u6027\u51cb\u4ea1\uff08\u6216\u6b7b\u4ea1\uff09\u6027\u75be\u75c5\uff0c\u5728\u7406\u8bba\u4e0a\u5b58\u5728\u7740\u5e94\u7528\u7ec6\u80de\u66ff\u4ee3\u7597\u6cd5\u5c24\u5176\u662f\u5e72\u7ec6\u80de\u6cbb\u7597\u7684\u53ef\u80fd\u6027\u3002\u5e72\u7ec6\u80de\u6cbb\u7597\u9752\u5149\u773c\u53ef\u80fd\u7684\u4f5c\u7528\u4f4d\u70b9\u5e94\u4f4d\u4e8e\u89c6\u7f51\u819c\u795e\u7ecf\u8282\u7ec6\u80de\u3001\u89c6\u4e73\u5934\u548c\u5c0f\u6881\u7f51\uff1a(1)\u76ee\u524d\u5927\u90e8\u5206\u7814\u7a76\u96c6\u4e2d\u4e8e\u89c6\u7f51\u819c\u795e\u7ecf\u8282\u7ec6\u80de\u7684\u66ff\u4ee3\u6cbb\u7597\uff0c\u4f46\u76ee\u524d\u79fb\u690d\u540e\u5e76\u6ca1\u6709\u5f97\u5230\u9884\u671f\u7684\u7ed3\u6784\u548c\u529f\u80fd\u7684\u4fee\u590d\uff0c\u540c\u65f6\u4e5f\u7f3a\u4e4f\u5bf9\u7ec6\u80de\u589e\u6b96\u3001\u5206\u5316\u8fdb\u884c\u5168\u7a0b\u76d1\u63a7\u7684\u624b\u6bb5\u3002(2)\u5c0f\u6881\u7f51\u7ec6\u80de\u91cd\u5efa\u5219\u4e3b\u8981\u662f\u66ff\u4ee3\u53d8\u6027\u7684\u5de9\u819c-\u89d2\u819c\u7ec6\u80de\u3002(3)\u5e72\u7ec6\u80de\u53ef\u80fd\u66ff\u4ee3\u53d8\u6027\u7684\u89c6\u4e73\u5934\u7ec6\u80de\uff08\u4e3b\u8981\u662f\u661f\u5f62\u80f6\u8d28\u7ec6\u80de\uff09\u6216\u4fc3\u8fdb\u89c6\u795e\u7ecf\u9ad3\u9798\u5316\u3002<\/span><\/p>\n<p class=\"\" style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;word-wrap: break-word !important;\"><img class=\"\"     style=\"box-sizing: border-box !important;word-wrap: break-word !important;width: auto !important;visibility: visible !important;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/07\/beepress7-1532685164.jpg\" alt=\"\u804a\u4e00\u804a\u5e72\u7ec6\u80de\u6cbb\u7597\u773c\u75be\" title=\"\u804a\u4e00\u804a\u5e72\u7ec6\u80de\u6cbb\u7597\u773c\u75be\"  \/><\/p>\n<p style=\"margin-top: 15px;margin-bottom: 15px;max-width: 100%;min-height: 1em;line-height: 1.75em;text-indent: 2em;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 15px;box-sizing: border-box !important;word-wrap: break-word !important;\">\u9aa8\u9ad3\u7ec6\u80de\u4e2d\u7684\u9020\u8840\u548c\u95f4\u5145\u8d28\u6210\u5206\u6709\u52a9\u4e8e\u53d7\u635f\u5668\u5b98\u7684\u4fee\u590d\uff0c\u6709\u4eba\u5c1d\u8bd5\u7528MSCs \u6cbb\u7597\u6162\u6027\u9752\u5149\u773c\u30022013\u5e74\uff0cStem Cells\u6742\u5fd7\u53d1\u8868\u4e86\u4e00\u7bc7\u6587\u7ae0\u300aTransplantation of Mesenchymal Stem Cells Promotes TissueRegeneration in a Glaucoma Model Through Laser-Induced Paracrine FactorSecretion and Progenitor Cell Recruitment\u300b[6]\u3002\u6765\u81ea\u52a0\u62ff\u5927\u7684\u7814\u7a76\u4eba\u5458\u5728\u9752\u5149\u773c\u6a21\u578b\u4e2d\u79fb\u690d\u5165<span style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\">MSCs&nbsp;<\/span>\uff0c\u901a\u8fc7\u6fc0\u5149\u8bf1\u53d1\u7684\u65c1\u5206\u6ccc\u56e0\u5b50\u5206\u6ccc\u548c\u7956\u7ec6\u80de\u589e\u6b96\u53ef\u4ee5\u4fc3\u8fdb\u9752\u5149\u773c\u7684\u7ec4\u7ec7\u518d\u751f\u3002\u5b9e\u9a8c\u663e\u793a\uff0c\u9aa8\u9ad3\u4e2d\u7684\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u8bf1\u53d1\u5c0f\u6881\u7f51\u7ec6\u80de\u7684\u518d\u751f\uff0c\u6ce8\u5c04\u8fdb\u773c\u524d\u623f\u6bd4\u9020\u8840\u7ec6\u80de\u66f4\u80fd\u6709\u6548\u5f15\u8d77\u773c\u5185\u538b(IOP)\u4e0b\u964d(p&lt;.001)\u3002\u6b64\u5916\uff0c<span style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\">MSCs&nbsp;<\/span>\u548c\u5b83\u4eec\u5206\u6ccc\u7684\u56e0\u5b50\u8bf1\u53d1\u776b\u72b6\u4f53\u4e2d\u7956\u7ec6\u80de\u6c60\u518d\u6d3b\u5316\uff0c\u4fc3\u8fdb\u7ec6\u80de\u589e\u6b96\u3002\u6fc0\u5149\u8bf1\u53d1\u7684\u7ec4\u7ec7\u91cd\u6784\u5c06&nbsp;<span style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\">MSCs&nbsp;<\/span>\u6309\u7167\u9884\u5b9a\u76ee\u6807\u5bfc\u5165\u53d7\u635f\u533a\u57df\uff0c\u5e76\u4f7f\u773c\u7956\u7ec6\u80de\u4e5f\u6709\u4e00\u5b9a\u7684\u589e\u52a0\u3002\u8be5\u7814\u7a76\u8bc1\u5b9e<span style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\">MSCs&nbsp;<\/span>\u53ca\u5176\u5206\u6ccc\u7ec4\u5206\u662f\u5f00\u89d2\u578b\u9752\u5149\u773c\u901a\u8fc7\u5c40\u90e8\u795e\u7ecf\u7956\u7ec6\u80de\u8fdb\u884c\u7ec4\u7ec7\u4fee\u590d\u7684\u5173\u952e\u4ecb\u8d28\u3002<\/span><\/p>\n<p style=\"margin-top: 15px;margin-bottom: 15px;max-width: 100%;min-height: 1em;line-height: 1.75em;text-indent: 0em;text-align: center;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 15px;box-sizing: border-box !important;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;color: rgb(62, 62, 62);box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;line-height: 1.75em;text-indent: 28px;font-size: 36px;box-sizing: border-box !important;word-wrap: break-word !important;\">\u5212\u91cd\u70b9<\/span><\/strong><\/span><\/p>\n<p style=\"margin-top: 10px;margin-bottom: 10px;max-width: 100%;min-height: 1em;line-height: 1.5em;box-sizing: border-box !important;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 15px;box-sizing: border-box !important;word-wrap: break-word !important;\">\u89d2\u819c\u7f18\u5e72\u7ec6\u80de\uff08LSC\uff0climbal stem cell\uff09<\/span><\/strong><\/p>\n<p style=\"margin-top: 10px;margin-bottom: 10px;max-width: 100%;min-height: 1em;line-height: 1.5em;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 15px;box-sizing: border-box !important;word-wrap: break-word !important;\">\u4e3b\u8981\u5b58\u5728\u4e8e\u89d2\u819c\u7f18\uff08Limbus\uff09\u7b49\u591a\u4e2a\u89d2\u819c\u90e8\u4f4d\u7684\u4e00\u79cd\u5e72\u7ec6\u80de\uff1b\u4e3b\u8981\u7279\u5f81\u662f\u9ad8\u8868\u8fbeP63\uff0c\u4f4e\u8868\u8fbeCD71\u3002<\/span><\/p>\n<p style=\"margin-top: 10px;margin-bottom: 10px;max-width: 100%;min-height: 1em;line-height: 1.5em;box-sizing: border-box !important;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 15px;box-sizing: border-box !important;word-wrap: break-word !important;\">\u8272\u7d20\u4e0a\u76ae\u7ec6\u80de\uff08RPE\uff0cretinal pigment epithelium\uff09<\/span><\/strong><\/p>\n<p style=\"margin-top: 10px;margin-bottom: 10px;max-width: 100%;min-height: 1em;line-height: 1.5em;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 15px;box-sizing: border-box !important;word-wrap: break-word !important;\">\u7531\u5355\u5c42\u8272\u7d20\u4e0a\u76ae\u7ec6\u80de\u6240\u6784\u6210\uff0c\u6392\u5217\u5341\u5206\u89c4\u5219\u3002\u7ec6\u80de\u5448\u591a\u89d2\u5f62\u3002\u4e3b\u8981\u7279\u5f81\u662fZO-1\uff0cbestrophin , MiTF\u7b49\u6807\u5fd7\u7269\u5448\u9633\u6027\uff1bOCT4,NANOG,\u4ee5\u53ca&nbsp;SOX2\u7b49\u6807\u5fd7\u7269\u5448\u9634\u6027\u3002<\/span><\/p>\n<p style=\"margin-top: 10px;margin-bottom: 10px;max-width: 100%;min-height: 1em;line-height: 1.5em;box-sizing: border-box !important;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 15px;box-sizing: border-box !important;word-wrap: break-word !important;\">\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\uff08MSCs\uff0cmesenchymal stem cells\uff09<\/span><\/strong><\/p>\n<p style=\"margin-top: 10px;margin-bottom: 10px;max-width: 100%;min-height: 1em;line-height: 1.5em;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 15px;box-sizing: border-box !important;word-wrap: break-word !important;\">\u4e3b\u8981\u4e8e\u5b58\u5728\u4e8e\u591a\u79cd\u7ec4\u7ec7(\u5982\u9aa8\u9ad3\u3001\u8110\u5e26\u3001\u80ce\u76d8\u3001\u8102\u80aa\u53ca\u5404\u79cd\u810f\u5668\u4e2d\u7b49)&nbsp;\u7684\u4e00\u79cd\u6210\u4f53\u5e72\u7ec6\u80de\uff0c\u80fd\u591f\u5206\u5316\u6210\u9aa8\u3001\u8f6f\u9aa8\u3001\u8102\u80aa\u7b49\u3002\u4e3b\u8981\u7279\u5f81\u662f\u8d34\u58c1\u751f\u957f\uff1b\u4e3b\u8981\u8868\u8fbeCD105\u3001CD73\u548cCD90\uff1bMSC\u5728\u4f53\u5916\u53ef\u4ee5\u5206\u5316\u4e3a\u6210\u9aa8\u7ec6\u80de\u3001\u8102\u80aa\u7ec6\u80de\u53ca\u6210\u8f6f\u9aa8\u7ec6\u80de\u3002<\/span><\/p>\n<p style=\"margin-top: 10px;margin-bottom: 10px;max-width: 100%;min-height: 1em;line-height: 1.5em;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 15px;box-sizing: border-box !important;word-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/span><\/p>\n<section style=\"margin-top: 5px;max-width: 100%;box-sizing: border-box;letter-spacing: 0.544px;color: rgb(62, 62, 62);font-size: 16px;font-family: \u5fae\u8f6f\u96c5\u9ed1;font-weight: bold;line-height: 25.6px;text-align: center;background-color: rgb(255, 255, 255);word-wrap: break-word !important;overflow-wrap: break-word !important;\">\n<section style=\"padding-top: 4px;padding-right: 10px;padding-bottom: 4px;max-width: 100%;box-sizing: border-box;border-top-width: 2px;border-top-style: solid;border-bottom-width: 2px;border-bottom-style: solid;display: inline-block;border-left-color: rgb(234, 234, 237);border-right-color: rgb(234, 234, 237);word-wrap: break-word !important;overflow-wrap: break-word !important;\">\n<section style=\"margin-top: -8px;max-width: 100%;box-sizing: border-box;white-space: normal;display: inline-block;float: left;width: 60px;background-color: rgb(254, 254, 254);word-wrap: break-word !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;color: rgb(63, 63, 63);font-size: 42px;box-sizing: border-box !important;word-wrap: break-word !important;overflow-wrap: break-word !important;\"><em style=\"max-width: 100%;list-style-type: none;-webkit-padding-start: 0px;-webkit-margin-before: 0px;-webkit-margin-after: 0px;-webkit-margin-start: 0px;-webkit-margin-end: 0px;box-sizing: border-box !important;word-wrap: break-word !important;overflow-wrap: break-word !important;\">4<\/em><\/span><\/section>\n<p><span style=\"max-width: 100%;white-space: pre-wrap;box-sizing: border-box !important;word-wrap: break-word !important;\">\u5c0f\u7ed3<\/span><\/section>\n<\/section>\n<p style=\"margin-top: 15px;margin-bottom: 15px;max-width: 100%;min-height: 1em;text-indent: 2em;line-height: 1.75em;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 15px;box-sizing: border-box !important;word-wrap: break-word !important;\">\u5c3d\u7ba1\u8bf8\u591a\u6587\u732e\u8bf4\u660e\uff0c\u53ef\u5229\u7528\u5404\u79cd\u5e72\u7ec6\u80de\u8fdb\u884c\u773c\u5185\u7ec6\u80de\u79fb\u690d\uff0c\u4f46\u6548\u679c\u5747\u4e0d\u662f\u5f88\u7406\u60f3\u3002\u5e72\u7ec6\u80de\u5728\u4f53\u5916\u57f9\u517b\u3001\u7eaf\u5316\u3001\u589e\u6b96\uff0c\u5b9a\u5411\u8bf1\u5bfc\uff0c\u4ee5\u53ca\u79fb\u690d\u65b9\u9762\u7684\u7814\u7a76\u8fdb\u5c55\uff0c\u4e3a\u4e00\u4e9b\u5e38\u89c4\u533b\u7597\u624b\u6bb5\u96be\u4ee5\u533b\u6cbb\u7684\u773c\u79d1\u75be\u75c5\u5e26\u6765\u4e86\u66d9\u5149\u3002\u4f46\u662f\uff0c\u5404\u79cd\u7684\u5e72\u7ec6\u80de\u90fd\u6709\u7740\u5176\u4e0d\u53ef\u56de\u907f\u7684\u7f3a\u70b9\uff0c\u5c24\u5176\u662f\u5982\u4f55\u5206\u5316\u4e3a\u7279\u5f02\u6027\u7684\u773c\u775b\u7ec8\u672b\u7ec6\u80de\u4e3a\u5176\u5171\u6027\u95ee\u9898\uff0c\u8fd9\u4e9b\u90fd\u6210\u4e3a\u5e72\u7ec6\u80de\u79fb\u690d\u6cbb\u7597\u5404\u7ec4\u7ec7\u773c\u79d1\u75be\u75c5\u7684\u969c\u788d\u3002<\/span><\/p>\n<p style=\"margin-top: 15px;margin-bottom: 15px;max-width: 100%;min-height: 1em;text-indent: 0em;line-height: 1.5em;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 14px;color: rgb(0, 122, 170);box-sizing: border-box !important;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\">\u6b65\u6b65\u5148\u751f\uff1a\u672c\u6587\u6210\u7a3f\u4e8e2014.7\uff0c\u5f53\u65f6\u5e94\u9080\u7ed9\u67d0\u6742\u5fd7\u5199\u7684\u4e00\u4e2a\u5c0f\u7efc\u8ff0\uff0c\u90a3\u4f1a\u513fACT\u516c\u53f8\u8fd8\u4e0d\u53ebOcata Therapeutics\u3002\u65f6\u81f3\u4eca\u5e74\uff0c\u5e72\u7ec6\u80de\u6cbb\u7597\u773c\u75be\u867d\u9891\u9891\u6377\u62a5\uff0c\u5374\u4f9d\u7136\u6ca1\u6709\u6253\u5f00\u901a\u5411\u5149\u660e\u7684\u5927\u95e8\uff0c\u9769\u547d\u5c1a\u672a\u6210\u529f\uff0c\u540c\u5fd7\u4ecd\u9700\u52aa\u529b\u3002<\/strong><\/span><\/p>\n<p style=\"margin-top: 15px;margin-bottom: 15px;max-width: 100%;min-height: 1em;line-height: 1.75em;text-indent: 0em;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 14px;box-sizing: border-box !important;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/strong><\/span><\/p>\n<p style=\"margin-top: 15px;margin-bottom: 5px;max-width: 100%;min-height: 1em;line-height: 1.75em;text-indent: 0em;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 14px;box-sizing: border-box !important;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\">\u53c2\u8003\u6587\u732e<\/strong><\/span><\/p>\n<p style=\"margin-top: 15px;margin-bottom: 15px;max-width: 100%;min-height: 1em;line-height: 1.75em;text-indent: 0em;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 14px;box-sizing: border-box !important;word-wrap: break-word !important;\"><\/span><\/p>\n<ul class=\"list-paddingleft-2\" style=\"\">\n<li>\n<p style=\"margin-top: 5px;margin-bottom: 5px;max-width: 100%;min-height: 1em;line-height: normal;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 12px;box-sizing: border-box !important;word-wrap: break-word !important;\">Majo F et al(2008)\uff1a&nbsp;Oligopotentstem cells are distributed throughout the mammalian ocular surface.&nbsp;Nature 456:250\u2013255<\/span><\/p>\n<\/li>\n<li>\n<p style=\"margin-bottom: 5px;max-width: 100%;min-height: 1em;line-height: normal;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 12px;box-sizing: border-box !important;word-wrap: break-word !important;\">Pelligrini Get al (2001)\uff1ap63identifies keratinocyte stem cell.&nbsp;ProcNatl Acad Sci USA&nbsp;98:3156\u20133161<\/span><\/p>\n<\/li>\n<li>\n<p style=\"margin-bottom: 5px;max-width: 100%;min-height: 1em;line-height: normal;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 12px;box-sizing: border-box !important;word-wrap: break-word !important;\">Hong Ouyang,et al. (2014):WNT7A and PAX6 define corneal epithelium homeostasis andpathogenesis. Nature.<\/span><\/p>\n<\/li>\n<li>\n<p style=\"margin-bottom: 5px;max-width: 100%;min-height: 1em;line-height: normal;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 12px;box-sizing: border-box !important;word-wrap: break-word !important;\">Paolo Rama,et al(2010):Limbal Stem-Cell Therapy and Long-Term Corneal Regeneration.<\/span><span style=\"max-width: 100%;font-size: 12px;font-family: inherit;text-decoration: inherit;letter-spacing: 0.544px;box-sizing: border-box !important;word-wrap: break-word !important;\">N Engl J MED 363: 147-155<\/span><\/p>\n<\/li>\n<li>\n<p style=\"margin-bottom: 5px;max-width: 100%;min-height: 1em;line-height: normal;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 12px;box-sizing: border-box !important;word-wrap: break-word !important;\">Schwartz SD&nbsp;et al (2012): Embryonic stemcell trials for macular degeneration: a preliminary report,TheLancet,379(9817):713-720.<\/span><\/p>\n<\/li>\n<li>\n<p style=\"margin-bottom: 5px;max-width: 100%;min-height: 1em;line-height: normal;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 12px;box-sizing: border-box !important;word-wrap: break-word !important;\">Manuguerra-Gagn_e,Boulos, Ammar et al.(2013)\uff1aTransplantation of Mesenchymal Stem CellsPromotes Tissue Regeneration in a Glaucoma Model Through Laser-InducedParacrine Factor Secretion and Progenitor Cell Recruitment. Stem Cells;31(6):1136-1148<\/span><\/p>\n<\/li>\n<\/ul>\n<p style=\"margin-right: auto;margin-bottom: 4px;margin-left: auto;max-width: 100%;box-sizing: border-box;min-height: 1em;white-space: normal;font-size: 21.6px;list-style-type: none;-webkit-padding-start: 0px;-webkit-margin-before: 0px;-webkit-margin-after: 0px;line-height: 0;width: 2.5em;text-align: right;word-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/p>\n<p style=\"margin-right: auto;margin-bottom: 4px;margin-left: auto;max-width: 100%;box-sizing: border-box;min-height: 1em;white-space: normal;font-size: 21.6px;list-style-type: none;-webkit-padding-start: 0px;-webkit-margin-before: 0px;-webkit-margin-after: 0px;line-height: 0;width: 2.5em;text-align: right;word-wrap: break-word !important;\"><img class=\"__bg_gif\"     style=\"margin-right: auto;margin-left: auto;line-height: 28.4444px;font-family: inherit;text-decoration: inherit;font-size: 16px;display: block;box-sizing: border-box !important;word-wrap: break-word !important;visibility: visible !important;width: 52.9792px !important;\" width=\"22px\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/07\/beepress0-1532685164.gif\" alt=\"\u804a\u4e00\u804a\u5e72\u7ec6\u80de\u6cbb\u7597\u773c\u75be\" title=\"\u804a\u4e00\u804a\u5e72\u7ec6\u80de\u6cbb\u7597\u773c\u75be\"  \/><\/p>\n<p style=\"margin-right: auto;margin-bottom: 4px;margin-left: auto;max-width: 100%;box-sizing: border-box;min-height: 1em;white-space: normal;font-size: 21.6px;list-style-type: none;-webkit-padding-start: 0px;-webkit-margin-before: 0px;-webkit-margin-after: 0px;line-height: 0;width: 2.5em;text-align: right;word-wrap: break-word !important;\"><br  style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"\" style=\"margin-top: 0.8em;margin-bottom: 0.8em;max-width: 100%;box-sizing: border-box;color: rgb(51, 51, 51);word-wrap: break-word !important;\">\n<p style=\"max-width: 100%;min-height: 1em;\"><span style=\"max-width: 100%;line-height: 28.4444px;box-sizing: border-box !important;word-wrap: break-word !important;\"><br  style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;\"><span style=\"max-width: 100%;line-height: 28.4444px;box-sizing: border-box !important;word-wrap: break-word !important;\">\u2014&nbsp; END &nbsp;\u2014&nbsp;<\/span><\/p>\n<p><span style=\"max-width: 100%;line-height: 28.4444px;box-sizing: border-box !important;word-wrap: break-word !important;\"><br  \/><\/span><\/p>\n<\/section>\n<p style=\"white-space: normal;max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><span style=\"max-width: 100%;color: rgb(136, 136, 136);font-family: \u5fae\u8f6f\u96c5\u9ed1;font-size: 15px;letter-spacing: 1px;background-color: rgb(254, 255, 255);box-sizing: border-box !important;word-wrap: break-word !important;\">\u6765\u6e90\uff1a\u5e72\u7ec6\u80de\u8005\u8bf4&nbsp; \u4f5c\u8005\uff1a\u6b65\u6b65\u5148\u751f&nbsp;<\/span><span style=\"max-width: 100%;color: rgb(136, 136, 136);font-family: \u5fae\u8f6f\u96c5\u9ed1;font-size: 15px;letter-spacing: 1px;background-color: rgb(254, 255, 255);box-sizing: border-box !important;word-wrap: break-word !important;\">&nbsp;<\/span><span style=\"max-width: 100%;font-family: \u5fae\u8f6f\u96c5\u9ed1;letter-spacing: 1px;font-size: 13.3333px;line-height: 21.3333px;text-align: center;box-sizing: border-box !important;word-wrap: break-word !important;\">\u5982\u6709\u4fb5\u6743\u8bf7\u8054\u7cfb\u5220\u9664<\/span><\/p>\n<p style=\"white-space: normal;max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><span style=\"max-width: 100%;font-family: \u5fae\u8f6f\u96c5\u9ed1;letter-spacing: 1px;font-size: 13.3333px;line-height: 21.3333px;text-align: center;box-sizing: border-box !important;word-wrap: break-word !important;\"><\/span><\/p>\n<p style=\"white-space: normal;max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><img class=\"\"      style=\"box-sizing: border-box !important;word-wrap: break-word !important;visibility: visible !important;width: auto !important;\" width=\"auto\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/07\/beepress9-1532685164.jpeg\" alt=\"\u804a\u4e00\u804a\u5e72\u7ec6\u80de\u6cbb\u7597\u773c\u75be\" title=\"\u804a\u4e00\u804a\u5e72\u7ec6\u80de\u6cbb\u7597\u773c\u75be\"  \/><\/p>\n<p style=\"white-space: normal;max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\">\n<blockquote class='keep-source'>\n<p>\u59cb\u53d1\u4e8e\u5fae\u4fe1\u516c\u4f17\u53f7\uff1a                         Cell                      <\/p>\n<\/blockquote>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>\u6b63\u6587 \u64b0\u6587\uff1a\u6b65\u6b65\u5148\u751f \u5e72\u7ec6\u80de\u5f88\u6709\u5e0c\u671b\u5e2e\u52a9\u6211\u4eec\u53bb\u8ba4\u8bc6\u548c\u6cbb\u7597\u591a\u79cd\u75be\u75c5\u3001\u635f\u4f24\u548c\u5176\u4ed6\u5065\u5eb7\u95ee\u9898\u3002\u5e72\u7ec6\u80de\u6cbb\u7597\u7684\u6f5c\u529b\u662f\u663e\u800c\u6613 [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":11097,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[2],"tags":[],"_links":{"self":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/11096"}],"collection":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/comments?post=11096"}],"version-history":[{"count":1,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/11096\/revisions"}],"predecessor-version":[{"id":11106,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/11096\/revisions\/11106"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/media\/11097"}],"wp:attachment":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/media?parent=11096"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/categories?post=11096"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/tags?post=11096"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}