{"id":111784,"date":"2019-05-17T00:00:50","date_gmt":"2019-05-20T01:26:43","guid":{"rendered":"http:\/\/www.05921.net\/index.php\/111784\/"},"modified":"2019-05-20T09:26:46","modified_gmt":"2019-05-20T01:26:46","slug":"c71b302848","status":"publish","type":"post","link":"https:\/\/www.05921.net\/index.php\/111784\/","title":{"rendered":"ASCO\u6700\u65b0\u6458\u8981\u7cbe\u9009\uff0c\u8fd9\u4e9b\u7814\u7a76\u8fdb\u5c55\u4f60\u90fd\u77e5\u9053\u5417\uff1f"},"content":{"rendered":"<div class=\"bpp-post-content\">\n<h1  style=\"margin-bottom: 0.8em;font-weight: inherit;font-size: 1.7em;white-space: normal;max-width: 100%;box-sizing: border-box;overflow-wrap: break-word;color: rgb(51, 51, 51);font-family: -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;letter-spacing: 0.544px;text-align: justify;background-color: rgb(255, 255, 255);line-height: 1.75em;\"><span style=\"font-size: 15px;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><strong style=\"max-width: 100%;line-height: 32px;font-size: 20px;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;font-family: SimSun;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><strong style=\"max-width: 100%;line-height: 32px;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><strong style=\"max-width: 100%;line-height: 32px;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><strong style=\"max-width: 100%;line-height: 32px;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><strong style=\"max-width: 100%;line-height: 1.75em;font-family: \u5fae\u8f6f\u96c5\u9ed1, sans-serif;font-size: 15px;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;color: rgb(0, 112, 192);font-family: \u6977\u4f53;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u258e\u836f\u660e<\/span><\/strong><strong style=\"max-width: 100%;line-height: 1.75em;font-family: \u5fae\u8f6f\u96c5\u9ed1, sans-serif;font-size: 15px;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;color: rgb(0, 112, 192);font-family: \u6977\u4f53;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u5eb7\u5fb7\/\u62a5\u9053<\/span><\/strong><\/strong><\/span><\/strong><\/strong><\/span><\/strong><\/strong><\/strong><\/span><\/strong><\/strong><\/span><\/strong><\/strong><\/span><\/h1>\n<p style=\"line-height: 1.75em;\"><span style=\"font-size: 15px;\">\u7f8e\u56fd\u4e34\u5e8a\u80bf\u7624\u5b66\u4f1a\uff08ASCO\uff092019\u5e74\u4f1a\u5373\u5c06\u4e8e5\u670831\u65e5-6\u67084\u65e5\u5728\u7f8e\u56fd\u829d\u52a0\u54e5\u53ec\u5f00\u3002<strong>\u8fd9\u662f\u4e16\u754c\u4e0a\u89c4\u6a21\u6700\u5927\u3001\u6c34\u5e73\u6700\u9ad8\u3001\u6700\u5177\u6743\u5a01\u6027\u7684\u4e34\u5e8a\u80bf\u7624\u5b66\u4f1a\u8bae\u4e4b\u4e00<\/strong>\u3002\u65e5\u524d\uff0cASCO\u516c\u5e03\u4e862019\u5e74\u5e74\u4f1a\u7684\u7814\u7a76\u6458\u8981\uff0c\u5176\u4e2d\u4e0d\u5c11\u6700\u65b0\u7814\u7a76\u5f15\u8d77\u4e86\u4e1a\u5185\u7684\u5e7f\u6cdb\u5173\u6ce8\u548c\u70ed\u8bae\u3002\u4eca\u5929\uff0c\u7684\u5fae\u4fe1\u56e2\u961f\u5c06\u4e0e\u8bfb\u8005\u4e00\u8d77\u76d8\u70b9\u6297\u764c\u9886\u57df\u7684\u6700\u65b0\u8fdb\u5c55\u3002<\/span><\/p>\n<p style=\"line-height: 1.75em;\"><span style=\"font-size: 15px;\"><br  \/><\/span><\/p>\n<p style=\"text-align: center;\"><img class=\"rich_pages\"      style=\"\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2019\/05\/8-1558315603.png\" alt=\"ASCO\u6700\u65b0\u6458\u8981\u7cbe\u9009\uff0c\u8fd9\u4e9b\u7814\u7a76\u8fdb\u5c55\u4f60\u90fd\u77e5\u9053\u5417\uff1f\" title=\"ASCO\u6700\u65b0\u6458\u8981\u7cbe\u9009\uff0c\u8fd9\u4e9b\u7814\u7a76\u8fdb\u5c55\u4f60\u90fd\u77e5\u9053\u5417\uff1f\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);font-family: -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;font-size: 17px;letter-spacing: 0.544px;text-align: justify;white-space: normal;background-color: rgb(255, 255, 255);box-sizing: border-box !important;overflow-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"  \/><\/p>\n<section style=\"max-width: 100%;box-sizing: border-box;font-family: -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;letter-spacing: 0.544px;text-align: justify;white-space: normal;color: rgb(62, 62, 62);font-size: 16px;background-color: rgb(255, 255, 255);overflow-wrap: break-word !important;\">\n<section class=\"\"  style=\"max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\">\n<section class=\"\" style=\"margin-top: 10px;max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\">\n<section class=\"\" style=\"padding-left: 5px;max-width: 100%;box-sizing: border-box;display: inline-block;width: 638.4px;border-width: 0px 0px 0px 10px;border-style: solid;border-left-color: rgb(0, 112, 192);border-right-color: rgb(0, 112, 192);overflow-wrap: break-word !important;\">\n<section class=\"\"  style=\"max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;color: rgb(0, 112, 192);overflow-wrap: break-word !important;\">\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;overflow-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\"><span style=\"font-size: 15px;\">KRAS G12C\u5c0f\u5206\u5b50\u6291\u5236\u5242\u9996\u6b21\u4e34\u5e8a\u8bd5\u9a8c\u7ed3\u679c\u79ef\u6781<\/span><\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"\"  style=\"max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\">\n<section class=\"\" style=\"margin-bottom: 8px;max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;background-color: rgb(0, 112, 192);height: 1px;overflow-wrap: break-word !important;\"><\/section>\n<\/section>\n<\/section>\n<\/section>\n<p style=\"text-align: center;\"><br  \/><\/p>\n<p style=\"text-align: center;\"><img class=\"rich_pages\"       style=\"\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2019\/05\/6-1558315603.jpg\" alt=\"ASCO\u6700\u65b0\u6458\u8981\u7cbe\u9009\uff0c\u8fd9\u4e9b\u7814\u7a76\u8fdb\u5c55\u4f60\u90fd\u77e5\u9053\u5417\uff1f\" title=\"ASCO\u6700\u65b0\u6458\u8981\u7cbe\u9009\uff0c\u8fd9\u4e9b\u7814\u7a76\u8fdb\u5c55\u4f60\u90fd\u77e5\u9053\u5417\uff1f\"  \/><\/p>\n<p style=\"text-align: center;\"><br  \/><\/p>\n<p style=\"line-height: 1.75em;\"><span style=\"font-size: 15px;\">\u5b89\u8fdb\uff08Amgen\uff09\u516c\u53f8\u5c06\u5728ASCO\u5e74\u4f1a\u516c\u5e03\u8be5\u516c\u53f8\u5f00\u53d1\u7684AMG 510\u5728\u9996\u6b21\u4eba\u4f53\u8bd5\u9a8c\u4e2d\u83b7\u5f97\u7684\u521d\u6b65\u6570\u636e\u3002\u8fd9\u98791\u671f\u8bd5\u9a8c\u7ed3\u679c\u5907\u53d7\u4eba\u4eec\u5173\u6ce8\u7684\u539f\u56e0\u662fAMG 510\u662f\u51e0\u5341\u5e74\u4ee5\u6765\uff0c\u4e3a\u6570\u4e0d\u591a\u7684\u6210\u529f\u9776\u5411KRAS\u7684\u5c0f\u5206\u5b50\u6291\u5236\u5242\u4e4b\u4e00\u3002<strong>\u5b83\u80fd\u591f\u4e0e\u643a\u5e26G12C\u7a81\u53d8\u7684KRAS\u86cb\u767d\u5171\u4ef7\u7ed3\u5408\uff0c\u5c06KRAS\u86cb\u767d\u56fa\u5b9a\u5728\u5931\u6d3b\u6784\u8c61<\/strong>\u3002<em>KRAS<\/em>\u57fa\u56e0\u7a81\u53d8\u53ef\u80fd\u51fa\u73b0\u572825%\u7684\u764c\u75c7\u4e2d\uff0c\u800c\u5927\u7ea614%\u7684\u80ba\u817a\u764c\u643a\u5e26G12C\u7a81\u53d8\u3002<\/span><\/p>\n<p style=\"line-height: 1.75em;\"><span style=\"font-size: 15px;\"><br  \/><\/span><\/p>\n<p style=\"line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(0, 112, 192);\">\u76f8\u5173\u9605\u8bfb\uff1a<\/span><a href=\"https:\/\/mp.weixin.qq.com\/s?__biz=MzAwMDA5NTIxNQ==&amp;mid=2649982182&amp;idx=1&amp;sn=94d4728c3d312947463b537400a5899d&amp;scene=21#wechat_redirect\" target=\"_blank\" style=\"text-decoration: underline;font-size: 15px;color: rgb(0, 112, 192);\" >\u60ca\u827340\u5e74\u7684\u7b49\u5f85\uff1a\u9501\u5b9a&#8221;\u4e0d\u53ef\u6210\u836f\u9776\u70b9&#8221;\uff0cKRAS\u6291\u5236\u5242\u6b65\u5165\u4e34\u5e8a\u8bd5\u9a8c<\/a><\/p>\n<p style=\"line-height: 1.75em;\"><span style=\"font-size: 15px;\"><br  \/><\/span><\/p>\n<p style=\"line-height: 1.75em;\"><span style=\"font-size: 15px;\">\u5728\u8fd9\u9879\u5f00\u653e\u6807\u7b7e\uff0c\u591a\u4e2d\u5fc31\u671f\u4e34\u5e8a\u8bd5\u9a8c\u4e2d\uff0c22\u540d\u643a\u5e26KRAS G12C\u7a81\u53d8\u7684\u5c40\u90e8\u665a\u671f\u6216\u8f6c\u79fb\u6027\u5b9e\u4f53\u7624\u60a3\u8005\u52a0\u5165\u4e86\u8bd5\u9a8c\u3002\u8fd9\u4e9b\u60a3\u8005\u90fd\u5df2\u7ecf\u63a5\u53d7\u8fc7\u591a\u79cd\u524d\u671f\u7597\u6cd5\u7684\u6cbb\u7597\u3002\u5728\u63a5\u53d7\u7597\u6548\u8bc4\u4f30\u768410\u540d\u60a3\u8005\u4e2d\uff0c\u4e24\u540d\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\uff08NSCLC\uff09\u60a3\u8005\u8fbe\u5230\u90e8\u5206\u7f13\u89e3\uff0c6\u540d\u60a3\u8005\u75be\u75c5\u7a33\u5b9a\uff0c2\u540d\u60a3\u8005\u75be\u75c5\u6076\u5316\u3002<\/span><br  \/><\/p>\n<p style=\"line-height: 1.75em;\"><span style=\"font-size: 15px;\"><br  \/><\/span><\/p>\n<p style=\"line-height: 1.75em;\"><span style=\"font-size: 15px;\">\u503c\u5f97\u6ce8\u610f\u7684\u662f\uff0c\u8fd910\u540d\u60a3\u8005\u4e2d\u67096\u540dNSCLC\u60a3\u8005\uff0c\u5728\u8fd9\u4e00\u4e9a\u7fa4\u4e2d\uff0c\u4e24\u540d\u60a3\u8005\u8fbe\u5230\u90e8\u5206\u7f13\u89e3\uff0c\u4e24\u540d\u60a3\u8005\u75be\u75c5\u7a33\u5b9a\u3002\u8fd9\u610f\u5473\u7740<strong>AMG 510\u5728NSCLC\u60a3\u8005\u4e2d\u8fbe\u523033%\u7684\u603b\u7f13\u89e3\u7387\u548c66%\u7684\u75be\u75c5\u63a7\u5236\u7387<\/strong>\u3002<\/span><\/p>\n<p style=\"line-height: 1.75em;\"><span style=\"font-size: 15px;\"><br  \/><\/span><\/p>\n<p style=\"line-height: 1.75em;\"><span style=\"font-size: 15px;\">\u5b89\u8fdb\u516c\u53f8\u5c06\u5728ASCO\u5e74\u4f1a\u4e0a\u516c\u5e03\u8fd9\u4e00\u8bd5\u9a8c\u7684\u6700\u65b0\u7ed3\u679c\uff0c\u540c\u65f6\u8be5\u516c\u53f8\u8ba1\u5212\u5c06\u542f\u52a8\u4e34\u5e8a\u8bd5\u9a8c\uff0c\u68c0\u6d4bAMG 510\u4e0e\u6297PD-1\u7597\u6cd5\u8054\u7528\u7684\u6cbb\u7597\u6548\u679c\u3002<\/span><\/p>\n<p style=\"line-height: 1.75em;\"><span style=\"font-size: 15px;\"><br  \/><\/span><\/p>\n<section style=\"white-space: normal;max-width: 100%;box-sizing: border-box;letter-spacing: 0.544px;color: rgb(62, 62, 62);font-size: 16px;background-color: rgb(255, 255, 255);overflow-wrap: break-word !important;\">\n<section class=\"\"  style=\"max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\">\n<section class=\"\" style=\"margin-top: 10px;max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\">\n<section class=\"\" style=\"padding-left: 5px;max-width: 100%;box-sizing: border-box;display: inline-block;width: 638.4px;border-width: 0px 0px 0px 10px;border-style: solid;border-left-color: rgb(0, 112, 192);border-right-color: rgb(0, 112, 192);overflow-wrap: break-word !important;\">\n<section class=\"\"  style=\"max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;color: rgb(0, 112, 192);overflow-wrap: break-word !important;\">\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;overflow-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\"><span style=\"font-size: 15px;\"><span style=\"font-size: 15px;\">\u7f57\u6c0f\u7cbe\u51c6\u7597\u6cd5\u6cbb\u7597\u513f\u7ae5\u8111\u7624\u83b7\u5f97\u79ef\u6781\u7ed3\u679c<\/span><\/span><\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"\"  style=\"max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\">\n<section class=\"\" style=\"margin-bottom: 8px;max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;background-color: rgb(0, 112, 192);height: 1px;overflow-wrap: break-word !important;\"><\/section>\n<\/section>\n<\/section>\n<\/section>\n<p style=\"text-align: center;\"><br  \/><\/p>\n<p style=\"text-align: center;\"><img class=\"rich_pages\"       style=\"\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2019\/05\/6-1558315604.png\" alt=\"ASCO\u6700\u65b0\u6458\u8981\u7cbe\u9009\uff0c\u8fd9\u4e9b\u7814\u7a76\u8fdb\u5c55\u4f60\u90fd\u77e5\u9053\u5417\uff1f\" title=\"ASCO\u6700\u65b0\u6458\u8981\u7cbe\u9009\uff0c\u8fd9\u4e9b\u7814\u7a76\u8fdb\u5c55\u4f60\u90fd\u77e5\u9053\u5417\uff1f\"  \/><\/p>\n<p style=\"line-height: 1.75em;\"><span style=\"font-size: 15px;\"><br  \/><\/span><\/p>\n<p style=\"line-height: 1.75em;\"><span style=\"font-size: 15px;\">\u53bb\u5e74\uff0cLoxo Oncology\u7684\u201c\u5e7f\u8c31\u201d\u6297\u764c\u836f<\/span><a href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MzAwMDA5NTIxNQ==&amp;mid=2649978927&amp;idx=2&amp;sn=5d7efd793d0ee77d9187d5f3d2b675c9&amp;chksm=82e9feafb59e77b981ff0e4c4502f4802916318e9d1640cd8d506b992038c6ff8e5ffe1a22a5&amp;scene=21#wechat_redirect\" target=\"_blank\"  style=\"text-decoration: underline;font-size: 15px;color: rgb(0, 112, 192);\" ><span style=\"font-size: 15px;color: rgb(0, 112, 192);\">larotrectinib\u83b7\u5f97FDA\u6279\u51c6\u4e0a\u5e02<\/span><\/a><span style=\"font-size: 15px;\">\u3002\u5b83\u88ab\u8ba4\u4e3a\u662f\u7cbe\u51c6\u533b\u7597\u7684\u4e00\u4e2a\u91cd\u8981\u91cc\u7a0b\u7891\u3002\u9664\u4e86larotrectinib\u4ee5\u5916\uff0c\u7f57\u6c0f\uff08Roche\uff09\u65d7\u4e0b\u57fa\u56e0\u6cf0\u514b\uff08Genentech\uff09\u516c\u53f8\u5f00\u53d1\u7684entrectinib\u4e5f\u662f\u4e00\u6b3e\u9488\u5bf9\u7279\u5b9a\u57fa\u56e0\u53d8\u5f02\uff0c\u4e0d\u9650\u764c\u79cd\u7684\u6297\u764c\u7597\u6cd5\u3002<strong>\u5b83\u80fd\u591f\u9776\u5411\u643a\u5e26<em>NTRK<\/em>\uff0c<em>ROS1<\/em>\u548c<em>ALK1<\/em>\u57fa\u56e0\u878d\u5408\u7684\u80bf\u7624\uff0c\u800c\u4e14\u53ef\u4ee5\u7a7f\u8d8a\u8840\u8111\u5c4f\u969c<\/strong>\u3002<\/span><\/p>\n<p style=\"line-height: 1.75em;\"><span style=\"font-size: 15px;\"><br  \/><\/span><\/p>\n<p style=\"line-height: 1.75em;\"><span style=\"font-size: 15px;\">\u5728\u4eca\u5e74\u7684ASCO\u5e74\u4f1a\u4e0a\uff0c\u57fa\u56e0\u6cf0\u514b\u516c\u53f8\u5c06\u516c\u5e03\u8fd9\u4e00\u836f\u7269\u6cbb\u7597\u513f\u7ae5\u8111\u7624\u548c\u5b9e\u4f53\u7624\u60a3\u8005\u76841\u671f\u4e34\u5e8a\u7ed3\u679c\u3002\u5728\u8fd9\u9879\u8bd5\u9a8c\u4e2d\uff0c\u643a\u5e26<em>NTRK<\/em>\u3001<em>ROS1<\/em>\u6216<em>ALK<\/em>\u57fa\u56e0\u878d\u5408\u7684\u5b9e\u4f53\u7624\u548c\u4e2d\u67a2\u795e\u7ecf\u7cfb\u7edf\uff08CNS\uff09\u80bf\u7624\u513f\u7ae5\u60a3\u8005\uff0c\u4ee5\u53ca\u80f6\u8d28\u6bcd\u7ec6\u80de\u7624\u513f\u7ae5\u60a3\u8005\u63a5\u53d7\u4e86entrectinib\u7684\u6cbb\u7597\u3002<\/span><\/p>\n<p style=\"line-height: 1.75em;\"><span style=\"font-size: 15px;\"><br  \/><\/span><\/p>\n<p style=\"line-height: 1.75em;\"><span style=\"font-size: 15px;\">\u8bd5\u9a8c\u7ed3\u679c\u8868\u660e\uff0c\u57286\u540d\u643a\u5e26\u57fa\u56e0\u878d\u5408\u7684CNS\u80bf\u7624\u60a3\u8005\u4e2d\uff0c1\u540d\u60a3\u8005\u8fbe\u5230\u5b8c\u5168\u7f13\u89e3\uff0c3\u540d\u8fbe\u5230\u90e8\u5206\u7f13\u89e3\uff0c1\u540d\u8fbe\u5230\u672a\u786e\u8ba4\u7684\u90e8\u5206\u7f13\u89e3\uff0c1\u540d\u60a3\u8005\u5c1a\u672a\u63a5\u53d7\u8bc4\u4f30\u3002\u57286\u540d\u643a\u5e26\u57fa\u56e0\u878d\u5408\u7684\u9885\u5916\u5b9e\u4f53\u7624\u60a3\u8005\u4e2d\uff0c1\u540d\u8fbe\u5230\u5b8c\u5168\u7f13\u89e3\uff0c5\u540d\u8fbe\u5230\u90e8\u5206\u7f13\u89e3\u3002\u572815\u540d\u4e0d\u643a\u5e26\u57fa\u56e0\u878d\u5408\u7684\u80f6\u8d28\u6bcd\u7ec6\u80de\u7624\u60a3\u8005\u4e2d\uff0c1\u540d\u643a\u5e26ALK F1174L\u7a81\u53d8\u7684\u60a3\u8005\u8fbe\u5230\u5b8c\u5168\u7f13\u89e3\u3002<\/span><\/p>\n<p style=\"line-height: 1.75em;\"><span style=\"font-size: 15px;\"><br  \/><\/span><\/p>\n<p style=\"line-height: 1.75em;\"><span style=\"font-size: 15px;\">\u8fd9\u4e9b\u7ed3\u679c\u8868\u660e\uff0c<strong>\u5bf9\u4e8e\u643a\u5e26<em>NTRK<\/em>\u3001<em>ROS1<\/em>\u6216<em>ALK<\/em>\u57fa\u56e0\u878d\u5408\u7684\u96be\u6cbb\u6027\u513f\u7ae5CNS\u80bf\u7624\u548c\u5b9e\u4f53\u7624\u60a3\u8005\u6765\u8bf4\uff0centrectinib\u8fbe\u5230100%\uff0811\/11\uff09\u7684\u7f13\u89e3\u7387<\/strong>\u3002\u867d\u7136\u8fd9\u9879\u8bd5\u9a8c\u7684\u6837\u672c\u6570\u5f88\u5c0f\uff0c\u4f46\u662fentrectinib\u7684\u5353\u8d8a\u7597\u6548\u652f\u6301\u5176\u8fdb\u4e00\u6b65\u7684\u4e34\u5e8a\u5f00\u53d1\u3002<\/span><\/p>\n<p style=\"line-height: 1.75em;\"><span style=\"font-size: 15px;\"><br  \/><\/span><\/p>\n<section style=\"white-space: normal;max-width: 100%;box-sizing: border-box;letter-spacing: 0.544px;color: rgb(62, 62, 62);font-size: 16px;background-color: rgb(255, 255, 255);overflow-wrap: break-word !important;\">\n<section class=\"\"  style=\"max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\">\n<section class=\"\" style=\"margin-top: 10px;max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\">\n<section class=\"\" style=\"padding-left: 5px;max-width: 100%;box-sizing: border-box;display: inline-block;width: 638.4px;border-width: 0px 0px 0px 10px;border-style: solid;border-left-color: rgb(0, 112, 192);border-right-color: rgb(0, 112, 192);overflow-wrap: break-word !important;\">\n<section class=\"\"  style=\"max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;color: rgb(0, 112, 192);overflow-wrap: break-word !important;\">\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;overflow-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\"><span style=\"font-size: 15px;\"><span style=\"font-size: 15px;\">MacroGenics\u6539\u826fHER2\u6297\u4f53\u8fbe\u52303\u671f\u4e34\u5e8a\u7ec8\u70b9<\/span><\/span><\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"\"  style=\"max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\">\n<section class=\"\" style=\"margin-bottom: 8px;max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;background-color: rgb(0, 112, 192);height: 1px;overflow-wrap: break-word !important;\"><\/section>\n<\/section>\n<\/section>\n<\/section>\n<p style=\"line-height: 1.75em;\"><br  \/><span style=\"font-size: 15px;\"><\/span><\/p>\n<p style=\"text-align: center;\"><img class=\"rich_pages\"      style=\"\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2019\/05\/10-1558315604.png\" alt=\"ASCO\u6700\u65b0\u6458\u8981\u7cbe\u9009\uff0c\u8fd9\u4e9b\u7814\u7a76\u8fdb\u5c55\u4f60\u90fd\u77e5\u9053\u5417\uff1f\" title=\"ASCO\u6700\u65b0\u6458\u8981\u7cbe\u9009\uff0c\u8fd9\u4e9b\u7814\u7a76\u8fdb\u5c55\u4f60\u90fd\u77e5\u9053\u5417\uff1f\"  \/><\/p>\n<p style=\"line-height: 1.75em;\"><span style=\"font-size: 15px;\"><\/span><br  \/><\/p>\n<p style=\"line-height: 1.75em;\"><span style=\"font-size: 15px;\">\u4eca\u5e742\u6708\uff0cMacroGenics\u516c\u53f8\u5ba3\u5e03\uff0c\u8be5\u516c\u53f8\u5f00\u53d1\u7684\u6539\u826fHER2\u5355\u514b\u9686\u6297\u4f53margetuximab\uff0c\u5728\u6cbb\u7597HER2+\u4e73\u817a\u764c\u60a3\u8005\u7684\u5173\u952e\u60273\u671f\u4e34\u5e8a\u8bd5\u9a8cSOPHIA\u4e2d\uff0c<\/span><a href=\"https:\/\/mp.weixin.qq.com\/s?__biz=MzAwMDA5NTIxNQ==&amp;mid=2649981014&amp;idx=2&amp;sn=964683f82550da7e2372e4b2e60d73fc&amp;scene=21#wechat_redirect\" target=\"_blank\" style=\"text-decoration: underline;font-size: 15px;color: rgb(0, 112, 192);\" ><span style=\"font-size: 15px;color: rgb(0, 112, 192);\">\u8fbe\u5230\u8bd5\u9a8c\u4e3b\u8981\u7ec8\u70b9<\/span><\/a><span style=\"font-size: 15px;\">\uff0c\u8fd9\u4e00\u6d88\u606f\u8ba9\u4eba\u4eec\u66f4\u52a0\u5173\u6ce8\u8be5\u516c\u53f8\u5728ASCO\u4e0a\u7684\u62a5\u544a\u3002<\/span><\/p>\n<p style=\"line-height: 1.75em;\"><span style=\"font-size: 15px;\"><br  \/><\/span><\/p>\n<p style=\"line-height: 1.75em;\"><strong><span style=\"font-size: 15px;\">Margetuximab\u662f\u4e00\u79cd\u5bf9\u6297\u4f53Fc\u7aef\u8fdb\u884c\u4f18\u5316\u7684HER2\u5355\u514b\u9686\u6297\u4f53<\/span><\/strong><span style=\"font-size: 15px;\">\u3002\u6297\u4f53Fc\u7aef\u901a\u8fc7\u4e0e\u8868\u8fbe\u5728\u514d\u75ab\u7ec6\u80de\u8868\u9762\u7684Fc\u03b3Rs\u53d7\u4f53\u7ed3\u5408\uff0c\u80fd\u591f\u5f15\u53d1\u591a\u79cd\u514d\u75ab\u53cd\u5e94\u3002 MacroGenics\u5229\u7528\u5176\u4e13\u6709\u7684Fc\u4f18\u5316\u6280\u672f\u5e73\u53f0\u589e\u52a0\u4e86margetuximab\u5bf9\u6fc0\u6d3b\u6027Fc\u03b3Rs\u53d7\u4f53\u7684\u4eb2\u548c\u529b\uff0c\u8fdb\u800c\u80fd\u589e\u5f3a\u6297\u4f53\u836f\u7269\u4e0e\u514d\u75ab\u6548\u5e94\u7ec6\u80de\u4e4b\u95f4\u7684\u76f8\u4e92\u4f5c\u7528\uff0c\u4ece\u800c\u63d0\u9ad8\u7ec6\u80de\u7684\u6548\u5e94\u529f\u80fd\u3002<\/span><\/p>\n<p style=\"line-height: 1.75em;\"><span style=\"font-size: 15px;\"><br  \/><\/span><\/p>\n<p style=\"line-height: 1.75em;\"><span style=\"font-size: 15px;\">\u6839\u636eASCO\u7684\u6458\u8981\u548c\u8be5\u516c\u53f8\u6628\u65e5\u53d1\u5e03\u7684\u65b0\u95fb\u7a3f\uff0cmargetuximab\u548c\u5316\u7597\u6784\u6210\u7684\u7ec4\u5408\u7597\u6cd5\u8fbe\u5230\u4e86SOPHIA\u8bd5\u9a8c\u7684\u4e3b\u8981\u7ec8\u70b9\u4e4b\u4e00\uff0cPFS\u663e\u8457\u4f18\u4e8e\u5bf9\u7167\u7ec4\u3002\u63a5\u53d7\u8fd9\u4e00\u7ec4\u5408\u7597\u6cd5\u6cbb\u7597\u7684\u60a3\u8005\u4e2d\u4f4dPFS\u4e3a5.8\u4e2a\u6708\uff0c\u63a5\u53d7\u66f2\u59a5\u73e0\u5355\u6297\u548c\u5316\u7597\u6cbb\u7597\u7684\u5bf9\u7167\u7ec4\u7684PFS\u4e3a4.9\u4e2a\u6708\u3002<\/span><\/p>\n<p style=\"line-height: 1.75em;\"><span style=\"font-size: 15px;\"><br  \/><\/span><\/p>\n<p style=\"line-height: 1.75em;\"><span style=\"font-size: 15px;\">\u503c\u5f97\u6ce8\u610f\u7684\u662f\uff0c<strong>\u5728\u643a\u5e26Fc\u03b3Rs 158F\u7b49\u4f4d\u57fa\u56e0\u7684\u60a3\u8005\u7fa4\u4e2d\uff0cmargetuximab\u7684\u8868\u73b0\u66f4\u4e3a\u51fa\u8272\uff0cPFS\u4e0e\u5bf9\u7167\u7ec4\u76f8\u6bd4\u63d0\u9ad8\u4e861.8\u4e2a\u6708\u3002\u8fd9\u4e9b\u60a3\u8005\u7684\u603b\u751f\u5b58\u671f\uff08OS\uff09\u6bd4\u5bf9\u7167\u7ec4\u63d0\u9ad8\u4e866.8\u4e2a\u6708<\/strong>\u3002\u643a\u5e26Fc\u03b3Rs 158F\u7b49\u4f4d\u57fa\u56e0\u7684\u60a3\u8005\u7fa4\u5360\u60a3\u8005\u603b\u6570\u768485%\uff0c\u8fd9\u4e9b\u60a3\u8005\u56e0\u4e3aFc\u03b3Rs\u7684\u53d8\u5f02\u5bf9\u66f2\u59a5\u73e0\u5355\u6297\u53cd\u5e94\u4e0d\u826f\u3002<\/span><\/p>\n<p style=\"line-height: 1.75em;\"><span style=\"font-size: 15px;\"><br  \/><\/span><\/p>\n<p style=\"line-height: 1.75em;\"><span style=\"font-size: 15px;\">\u8f6c\u79fb\u6027HER2+\u4e73\u817a\u764c\u60a3\u8005\u5728\u5bf9\u83b7\u6279HER2\u6297\u4f53\u7597\u6cd5\u4ea7\u751f\u6297\u6027\u540e\uff0c\u6ca1\u6709\u6709\u6548\u7684\u6cbb\u7597\u9009\u62e9\u3002Margetuximab\u7684\u8868\u73b0\u8bc1\u660e\u5b83\u53ef\u80fd\u4e3a\u8fd9\u4e9b\u60a3\u8005\u63d0\u4f9b\u65b0\u7684\u6cbb\u7597\u9009\u62e9\u3002<\/span><\/p>\n<p style=\"line-height: 1.75em;\"><span style=\"font-size: 15px;\"><br  \/><\/span><\/p>\n<section style=\"white-space: normal;max-width: 100%;box-sizing: border-box;letter-spacing: 0.544px;color: rgb(62, 62, 62);font-size: 16px;background-color: rgb(255, 255, 255);overflow-wrap: break-word !important;\">\n<section class=\"\"  style=\"max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\">\n<section class=\"\" style=\"margin-top: 10px;max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\">\n<section class=\"\" style=\"padding-left: 5px;max-width: 100%;box-sizing: border-box;display: inline-block;width: 638.4px;border-width: 0px 0px 0px 10px;border-style: solid;border-left-color: rgb(0, 112, 192);border-right-color: rgb(0, 112, 192);overflow-wrap: break-word !important;\">\n<section class=\"\"  style=\"max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;color: rgb(0, 112, 192);overflow-wrap: break-word !important;\">\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;overflow-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\"><span style=\"font-size: 15px;\">\u7b2c\u4e00\u4e09\u5171\u516c\u5e03\u6297\u4f53\u5076\u8054\u836f\u7269\u521d\u6b65\u4e34\u5e8a\u7ed3\u679c<\/span><\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"\"  style=\"max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\">\n<section class=\"\" style=\"margin-bottom: 8px;max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;background-color: rgb(0, 112, 192);height: 1px;overflow-wrap: break-word !important;\"><\/section>\n<\/section>\n<\/section>\n<\/section>\n<p style=\"white-space: normal;line-height: 1.75em;\"><br  \/><\/p>\n<p style=\"white-space: normal;text-align: center;\"><img class=\"rich_pages\"       src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2019\/05\/5-1558315604.jpg\" alt=\"ASCO\u6700\u65b0\u6458\u8981\u7cbe\u9009\uff0c\u8fd9\u4e9b\u7814\u7a76\u8fdb\u5c55\u4f60\u90fd\u77e5\u9053\u5417\uff1f\" title=\"ASCO\u6700\u65b0\u6458\u8981\u7cbe\u9009\uff0c\u8fd9\u4e9b\u7814\u7a76\u8fdb\u5c55\u4f60\u90fd\u77e5\u9053\u5417\uff1f\"  \/><\/p>\n<p style=\"white-space: normal;line-height: 1.75em;\"><br  \/><\/p>\n<p style=\"white-space: normal;line-height: 1.75em;\"><span style=\"font-size: 15px;\">\u63d0\u5230\u9776\u5411HER2\u7684\u6297\u4f53\u7597\u6cd5\uff0c\u7b2c\u4e00\u4e09\u5171\u7684\u6297\u4f53\u5076\u8054\u836f\u7269\uff08ADC\uff09DS-8201\u56e0\u5176\u4f18\u5f02\u7684\u4e34\u5e8a\u8868\u73b0\u5f97\u5230\u4e86\u4e1a\u754c\u4eba\u58eb\u7684\u5e7f\u6cdb\u5173\u6ce8\u3002\u963f\u65af\u5229\u5eb7\u4e5f\u4e0e\u7b2c\u4e00\u4e09\u5171\u8fbe\u6210<\/span><a href=\"https:\/\/mp.weixin.qq.com\/s?__biz=MzAwMDA5NTIxNQ==&amp;mid=2649982606&amp;idx=4&amp;sn=8334f7a5edd61b22846757498f1aa1fa&amp;scene=21#wechat_redirect\" target=\"_blank\" style=\"color: rgb(0, 112, 192);text-decoration: underline;font-size: 15px;\" >69\u4ebf\u7f8e\u5143\u7684\u7814\u53d1\u534f\u8bae<\/a><span style=\"font-size: 15px;\">\uff0c\u5171\u540c\u5f00\u53d1\u8fd9\u6b3eADC\u3002\u800c\u5728\u672c\u5c4aASCO\u5e74\u4f1a\u4e0a\uff0c\u7b2c\u4e00\u4e09\u5171\u5c06\u4ecb\u7ecd\u53e6\u5916\u4e24\u6b3e\u4f7f\u7528\u540c\u6837\u6297\u4f53\u5076\u8054\u6280\u672f\u5f00\u53d1\u7684\u6297\u764cADC\u7684\u521d\u6b65\u4e34\u5e8a\u7ed3\u679c\u3002<\/span><\/p>\n<p style=\"white-space: normal;line-height: 1.75em;\"><br  \/><\/p>\n<p style=\"white-space: normal;line-height: 1.75em;\"><span style=\"font-size: 15px;\">DS-1062\u662f\u4e00\u6b3e\u9776\u5411Trop2\u7684ADC\uff0c\u76ee\u524d\u57281\u671f\u4e34\u5e8a\u8bd5\u9a8c\u4e2d\u6cbb\u7597NSCLC\u60a3\u8005\u3002\u521d\u6b65\u8bd5\u9a8c\u7ed3\u679c\u8868\u660e\uff0c\u572818\u540d\u53ef\u88ab\u8bc4\u4f30\u7684\u60a3\u8005\u4e2d\uff0c1\u540d\u8fbe\u5230\u90e8\u5206\u7f13\u89e3\uff0c8\u540d\u60a3\u8005\u75be\u75c5\u7a33\u5b9a\u3002<\/span><\/p>\n<p style=\"white-space: normal;line-height: 1.75em;\"><span style=\"font-size: 15px;\"><br  \/><\/span><\/p>\n<p style=\"white-space: normal;line-height: 1.75em;\"><span style=\"font-size: 15px;\">U3-1402\u662f\u4e00\u6b3e\u9776\u5411HER3\u7684ADC\uff0c\u5b83\u57281\u671f\u4e34\u5e8a\u8bd5\u9a8c\u4e2d\u6cbb\u7597\u96be\u6cbb\u6027EGFR\u9633\u6027NSCLC\u60a3\u8005\u3002\u5728<strong>13\u540d\u80fd\u591f\u88ab\u8bc4\u4f30\u7684\u60a3\u8005\u4e2d\uff0c2\u540d\u60a3\u8005\u8fbe\u5230\u90e8\u5206\u7f13\u89e3\uff0c12\u540d\u60a3\u8005\u7684\u80bf\u7624\u6700\u957f\u76f4\u5f84\u4e4b\u548c\uff08SLD\uff09\u6307\u6570\u51fa\u73b0\u4e0b\u964d\u3002<\/strong><\/span><\/p>\n<p style=\"white-space: normal;line-height: 1.75em;\"><br  \/><\/p>\n<p style=\"white-space: normal;line-height: 1.75em;\"><span style=\"font-size: 15px;\">\u8fd9\u4e24\u6b3e\u7597\u6cd5\u4ecd\u7136\u5904\u4e8e\u65e9\u671f\u4e34\u5e8a\u5f00\u53d1\u9636\u6bb5\uff0c\u4e0d\u8fc7\u7531\u4e8eDS-8201\u7684\u6210\u529f\uff0c\u4eba\u4eec\u4e5f\u5c06\u5bc6\u5207\u5173\u6ce8\u8fd9\u4e24\u6b3eADC\u7684\u8868\u73b0\uff0c\u770b\u770b\u7b2c\u4e00\u4e09\u5171\u7684\u521b\u65b0\u6297\u4f53\u5076\u8054\u6280\u672f\u80fd\u5426\u5728\u9776\u5411\u5176\u5b83\u6297\u539f\u7684\u6297\u4f53\u4e0a\u540c\u6837\u83b7\u5f97\u6210\u529f\u3002<\/span><\/p>\n<p style=\"line-height: 1.75em;\"><br  \/><\/p>\n<section style=\"white-space: normal;max-width: 100%;box-sizing: border-box;letter-spacing: 0.544px;color: rgb(62, 62, 62);font-size: 16px;background-color: rgb(255, 255, 255);overflow-wrap: break-word !important;\">\n<section class=\"\"  style=\"max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\">\n<section class=\"\" style=\"margin-top: 10px;max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\">\n<section class=\"\" style=\"padding-left: 5px;max-width: 100%;box-sizing: border-box;display: inline-block;width: 638.4px;border-width: 0px 0px 0px 10px;border-style: solid;border-left-color: rgb(0, 112, 192);border-right-color: rgb(0, 112, 192);overflow-wrap: break-word !important;\">\n<section class=\"\"  style=\"max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;color: rgb(0, 112, 192);overflow-wrap: break-word !important;\">\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;overflow-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\"><span style=\"font-size: 15px;\"><span style=\"font-size: 15px;\">Iovance\u80bf\u7624\u6d78\u6da6\u6dcb\u5df4\u7ec6\u80de\u7597\u6cd5\u4e34\u5e8a\u7ed3\u679c\u79ef\u6781<\/span><\/span><\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"\"  style=\"max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\">\n<section class=\"\" style=\"margin-bottom: 8px;max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;background-color: rgb(0, 112, 192);height: 1px;overflow-wrap: break-word !important;\"><\/section>\n<\/section>\n<\/section>\n<\/section>\n<p style=\"line-height: 1.75em;\"><br  \/><span style=\"font-size: 15px;\"><\/span><\/p>\n<p style=\"text-align: center;\"><img class=\"rich_pages\"      style=\"\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2019\/05\/2-1558315604.jpeg\" alt=\"ASCO\u6700\u65b0\u6458\u8981\u7cbe\u9009\uff0c\u8fd9\u4e9b\u7814\u7a76\u8fdb\u5c55\u4f60\u90fd\u77e5\u9053\u5417\uff1f\" title=\"ASCO\u6700\u65b0\u6458\u8981\u7cbe\u9009\uff0c\u8fd9\u4e9b\u7814\u7a76\u8fdb\u5c55\u4f60\u90fd\u77e5\u9053\u5417\uff1f\"  \/><\/p>\n<p style=\"line-height: 1.75em;\"><span style=\"font-size: 15px;\"><br  \/><\/span><\/p>\n<p style=\"line-height: 1.75em;\"><span style=\"font-size: 15px;\">Iovance\u516c\u53f8\u5ba3\u5e03\uff0c\u8be5\u516c\u53f8\u5f00\u53d1\u7684<strong>\u80bf\u7624\u6d78\u6da6\u6dcb\u5df4\u7ec6\u80de\uff08TIL\uff09\u7597\u6cd5LN-145\uff0c\u5728\u6cbb\u7597\u665a\u671f\u5bab\u9888\u764c\u60a3\u8005\u7684\u4e34\u5e8a\u8bd5\u9a8c\u4e2d\u8fbe\u523044%\u7684ORR\u548c89%\u7684\u75be\u75c5\u63a7\u5236\u7387<\/strong>\u3002\u5386\u53f2\u6570\u636e\u8868\u660e\uff0c\u7ecf\u5178PD-1\u6291\u5236\u5242\u6cbb\u7597\u7c7b\u4f3c\u60a3\u8005\u7684ORR\u4e3a14%\u3002<\/span><\/p>\n<p style=\"line-height: 1.75em;\"><span style=\"font-size: 15px;\"><br  \/><\/span><\/p>\n<p style=\"line-height: 1.75em;\"><span style=\"font-size: 15px;\">Iovance\u7684TIL\u7597\u6cd5\u4ece\u60a3\u8005\u4f53\u5185\u83b7\u53d6TIL\uff0c\u7136\u540e\u5728\u4f53\u5916\u4f7f\u7528IL-2\u7ec6\u80de\u56e0\u5b50\u523a\u6fc0TIL\u7684\u6269\u589e\u3002\u4f53\u5916\u523a\u6fc0\u624b\u6bb5\u4e0d\u4f46\u589e\u52a0\u4e86TIL\u7684\u6570\u91cf\uff0c\u800c\u4e14\u6fc0\u6d3b\u4e86TIL\u7684\u6297\u80bf\u7624\u80fd\u529b\u3002\u7136\u540e\uff0c\u8fd9\u4e9bTIL\u518d\u88ab\u6ce8\u56de\u60a3\u8005\u4f53\u5185\uff0c\u5b83\u4eec\u80fd\u591f\u66f4\u6709\u6548\u5730\u6740\u4f24\u80bf\u7624\u7ec6\u80de\u3002<\/span><\/p>\n<p style=\"line-height: 1.75em;\"><span style=\"font-size: 15px;\"><br  \/><\/span><\/p>\n<p style=\"line-height: 1.75em;\"><span style=\"font-size: 15px;\">\u63a5\u53d7LN-145\u6cbb\u7597\u7684\u60a3\u8005\u5e73\u5747\u63a5\u53d7\u8fc72.6\u79cd\u524d\u671f\u7597\u6cd5\u3002\u5728\u63a5\u53d71\u6b21\u6cbb\u7597\u4e4b\u540e\uff0c\u572827\u540d\u80fd\u591f\u88ab\u8bc4\u4f30\u7684\u60a3\u8005\u4e2d\uff0c1\u540d\u8fbe\u5230\u5b8c\u5168\u7f13\u89e3\uff0c9\u540d\u8fbe\u5230\u90e8\u5206\u7f13\u89e3\uff0c2\u540d\u8fbe\u5230\u672a\u786e\u8ba4\u7684\u90e8\u5206\u7f13\u89e3\u3002<\/span><\/p>\n<p style=\"line-height: 1.75em;\"><span style=\"font-size: 15px;\"><br  \/><\/span><\/p>\n<p style=\"line-height: 1.75em;\"><span style=\"font-size: 15px;\">Iovance\u516c\u53f8\u5e0c\u671b\u80fd\u591f\u57fa\u4e8e\u8fd9\u4e00\u8bd5\u9a8c\u7684\u79ef\u6781\u7ed3\u679c\uff0c\u5411\u7f8e\u56fdFDA\u9012\u4ea4\u76d1\u7ba1\u7533\u8bf7\u3002<\/span><\/p>\n<p style=\"line-height: 1.75em;\"><span style=\"font-size: 15px;\"><br  \/><\/span><\/p>\n<section style=\"white-space: normal;max-width: 100%;box-sizing: border-box;letter-spacing: 0.544px;color: rgb(62, 62, 62);font-size: 16px;background-color: rgb(255, 255, 255);overflow-wrap: break-word !important;\">\n<section class=\"\"  style=\"max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\">\n<section class=\"\" style=\"margin-top: 10px;max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\">\n<section class=\"\" style=\"padding-left: 5px;max-width: 100%;box-sizing: border-box;display: inline-block;width: 638.4px;border-width: 0px 0px 0px 10px;border-style: solid;border-left-color: rgb(0, 112, 192);border-right-color: rgb(0, 112, 192);overflow-wrap: break-word !important;\">\n<section class=\"\"  style=\"max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;color: rgb(0, 112, 192);overflow-wrap: break-word !important;\">\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;overflow-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\"><span style=\"font-size: 15px;\"><span style=\"font-size: 15px;\">Forty Seven\u516c\u5e03\u6297CD47\u6297\u4f53\u9996\u6b21\u4eba\u4f53\u8bd5\u9a8c\u7ed3\u679c<\/span><\/span><\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"\"  style=\"max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\">\n<section class=\"\" style=\"margin-bottom: 8px;max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;background-color: rgb(0, 112, 192);height: 1px;overflow-wrap: break-word !important;\"><\/section>\n<\/section>\n<\/section>\n<\/section>\n<p style=\"line-height: 1.75em;\"><br  \/><span style=\"font-size: 15px;\"><\/span><\/p>\n<p style=\"text-align: center;\"><img class=\"rich_pages\"      style=\"\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2019\/05\/1-1558315605.jpg\" alt=\"ASCO\u6700\u65b0\u6458\u8981\u7cbe\u9009\uff0c\u8fd9\u4e9b\u7814\u7a76\u8fdb\u5c55\u4f60\u90fd\u77e5\u9053\u5417\uff1f\" title=\"ASCO\u6700\u65b0\u6458\u8981\u7cbe\u9009\uff0c\u8fd9\u4e9b\u7814\u7a76\u8fdb\u5c55\u4f60\u90fd\u77e5\u9053\u5417\uff1f\"  \/><\/p>\n<p style=\"line-height: 1.75em;\"><span style=\"font-size: 15px;\"><br  \/><\/span><\/p>\n<p style=\"line-height: 1.75em;\"><span style=\"font-size: 15px;\">Forty Seven\u516c\u53f8\u5f00\u53d1\u7684\u6297CD47\u6297\u4f53Hu5F9-G4\u5f97\u5230\u5f88\u591a\u4e1a\u754c\u4eba\u58eb\u7684\u5173\u6ce8\uff0c\u56e0\u4e3a\u5b83\u662f\u4e00\u6b3e\u9776\u5411\u80bf\u7624\u7ec6\u80de\u8868\u8fbe\u7684\u201c\u522b\u5403\u6211\u201d\u4fe1\u53f7\u7684\u764c\u75c7\u514d\u75ab\u7597\u6cd5\u3002\u8fd9\u6b3e\u7597\u6cd5\u901a\u8fc7\u4e0e\u80bf\u7624\u7ec6\u80de\u8868\u9762\u8868\u8fbe\u7684CD47\u7ed3\u5408\uff0c\u963b\u6b62CD47\u53d1\u51fa\u201c\u522b\u5403\u6211\u201d\u4fe1\u53f7\uff0c\u6062\u590d\u5de8\u566c\u7ec6\u80de\u541e\u566c\u80bf\u7624\u7ec6\u80de\u7684\u80fd\u529b\u3002\u65e5\u524d\uff0c\u8be5\u516c\u53f8\u521a<\/span><a href=\"https:\/\/mp.weixin.qq.com\/s?__biz=MzAwMDA5NTIxNQ==&amp;mid=2649983698&amp;idx=2&amp;sn=8eebc12b427d50b90a7f0b51ef991bfd&amp;scene=21#wechat_redirect\" target=\"_blank\" style=\"text-decoration: underline;font-size: 15px;color: rgb(0, 112, 192);\" ><span style=\"font-size: 15px;color: rgb(0, 112, 192);\">\u4e0e\u963f\u65af\u5229\u5eb7\uff08AstraZeneca\uff09\u516c\u53f8\u8fbe\u6210\u7814\u53d1\u534f\u8bae<\/span><\/a><span style=\"font-size: 15px;\">\uff0c\u8bc4\u4f30Hu5F9-G4\uff085F9\uff09\u7597\u6cd5\uff0c\u4e0e\u5229\u59a5\u6614\u5355\u6297\uff08rituximab\uff09\u548c\u9776\u5411\u836fBTK\u6291\u5236\u5242Calquence\uff08acalabrutinib\uff09\u8054\u7528\uff0c\u6cbb\u7597\u5f25\u6f2b\u6027\u5927B\u7ec6\u80de\u6dcb\u5df4\u7624\u7684\u6548\u679c\u3002<\/span><\/p>\n<p style=\"line-height: 1.75em;\"><span style=\"font-size: 15px;\"><br  \/><\/span><\/p>\n<p style=\"line-height: 1.75em;\"><span style=\"font-size: 15px;\">\u5728ASCO\u5e74\u4f1a\u4e0a\uff0c\u8be5\u516c\u53f8\u5c06\u516c\u5e035F9\u7597\u6cd5\u5728\u9996\u6b21\u4eba\u7c7b\u4e34\u5e8a\u8bd5\u9a8c\u4e2d\u7684\u7ed3\u679c\u3002\u5728\u8fd9\u9879\u8bd5\u9a8c\u4e2d\uff0c5F9\u4f5c\u4e3a\u5355\u836f\u7597\u6cd5\uff0c\u6216\u8005\u4e0e\u963f\u624e\u80de\u82f7\u8054\u7528\uff0c\u6cbb\u7597\u6025\u6027\u9aa8\u9ad3\u6027\u767d\u8840\u75c5\uff08AML\uff09\u6216\u9aa8\u9ad3\u589e\u751f\u5f02\u5e38\u7efc\u5408\u5f81\uff08MDS\uff09\u60a3\u8005\u3002<\/span><\/p>\n<p style=\"line-height: 1.75em;\"><span style=\"font-size: 15px;\"><br  \/><\/span><\/p>\n<p style=\"line-height: 1.75em;\"><span style=\"font-size: 15px;\">\u8bd5\u9a8c\u7ed3\u679c\u8868\u660e\uff0c<strong>\u572815\u540d\u521d\u6cbbAML\/MDS\u60a3\u8005\u4e2d\uff0c5F9\u4e0e\u963f\u624e\u80de\u82f7\u8054\u7528\uff0c\u8ba98\u540d\u60a3\u8005\u8fbe\u5230\u5b8c\u5168\u7f13\u89e3<\/strong>\u3002\u572810\u540d\u590d\u53d1\/\u96be\u6cbb\u6027AML\/MDS\u60a3\u8005\u4e2d\uff0c\u4e00\u540d\u60a3\u8005\u5728\u63a5\u53d75F9\u5355\u836f\u7597\u6cd5\u540e\uff0c\u8fbe\u5230\u5f62\u6001\u5b66\u65e0\u767d\u8840\u75c5\u72b6\u6001\uff08MLFS\uff09\u3002\u622a\u81f32019\u5e741\u6708\uff0c<strong>\u6240\u6709\u83b7\u5f97\u7f13\u89e3\u7684\u60a3\u8005\u90fd\u672a\u51fa\u73b0\u590d\u53d1<\/strong>\uff0c\u5176\u4e2d\u4e24\u540d\u60a3\u8005\u6210\u529f\u63a5\u53d7\u9020\u8840\u79fb\u690d\u7597\u6cd5\u3002<\/span><\/p>\n<p style=\"line-height: 1.75em;\"><span style=\"font-size: 15px;\"><br  \/><\/span><\/p>\n<p style=\"line-height: 1.75em;\"><span style=\"font-size: 15px;\">\u8fd9\u4e9b\u7ed3\u679c\u663e\u793a\uff0c\u5c065F9\u7597\u6cd5\u4e0e\u7ec6\u80de\u6bd2\u6027\u5316\u7597\u8054\u7528\u53ef\u80fd\u662f\u4e00\u79cd\u6709\u6548\u7684\u6cbb\u7597\u7b56\u7565\u3002<\/span><\/p>\n<p style=\"line-height: 1.75em;\"><span style=\"font-size: 15px;\"><br  \/><\/span><\/p>\n<section style=\"white-space: normal;max-width: 100%;box-sizing: border-box;letter-spacing: 0.544px;color: rgb(62, 62, 62);font-size: 16px;background-color: rgb(255, 255, 255);overflow-wrap: break-word !important;\">\n<section class=\"\"  style=\"max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\">\n<section class=\"\" style=\"margin-top: 10px;max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\">\n<section class=\"\" style=\"padding-left: 5px;max-width: 100%;box-sizing: border-box;display: inline-block;width: 638.4px;border-width: 0px 0px 0px 10px;border-style: solid;border-left-color: rgb(0, 112, 192);border-right-color: rgb(0, 112, 192);overflow-wrap: break-word !important;\">\n<section class=\"\"  style=\"max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;color: rgb(0, 112, 192);overflow-wrap: break-word !important;\">\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;overflow-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\"><span style=\"font-size: 15px;\"><span style=\"font-size: 15px;\">GRAIL\u6db2\u4f53\u6d3b\u68c0\u7cbe\u786e\u5224\u65ad\u764c\u75c7\u7ec4\u7ec7\u8d77\u6e90\u548c\u5371\u9669\u7a0b\u5ea6<\/span><\/span><\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"\"  style=\"max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\">\n<section class=\"\" style=\"margin-bottom: 8px;max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;background-color: rgb(0, 112, 192);height: 1px;overflow-wrap: break-word !important;\"><\/section>\n<\/section>\n<\/section>\n<\/section>\n<p style=\"line-height: 1.75em;\"><br  \/><\/p>\n<p style=\"text-align: center;\"><img class=\"rich_pages\"      style=\"\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2019\/05\/10-1558315605.png\" alt=\"ASCO\u6700\u65b0\u6458\u8981\u7cbe\u9009\uff0c\u8fd9\u4e9b\u7814\u7a76\u8fdb\u5c55\u4f60\u90fd\u77e5\u9053\u5417\uff1f\" title=\"ASCO\u6700\u65b0\u6458\u8981\u7cbe\u9009\uff0c\u8fd9\u4e9b\u7814\u7a76\u8fdb\u5c55\u4f60\u90fd\u77e5\u9053\u5417\uff1f\"  \/><\/p>\n<p style=\"line-height: 1.75em;\"><span style=\"font-size: 15px;\"><br  \/><\/span><\/p>\n<p style=\"line-height: 1.75em;\"><span style=\"font-size: 15px;\">GRAIL\u516c\u53f8\u65e5\u524d\u5ba3\u5e03\uff0c\u8be5\u516c\u53f8\u5f00\u53d1\u7684\u57fa\u4e8e\u4e0b\u4e00\u4ee3\u57fa\u56e0\u6d4b\u5e8f\u6280\u672f\uff08NGS\uff09\u7684\u6db2\u4f53\u6d3b\u68c0\u83b7\u5f97\u4e86\u7f8e\u56fdFDA\u6388\u4e88\u7684<\/span><a href=\"https:\/\/mp.weixin.qq.com\/s?__biz=MzAwMDA5NTIxNQ==&amp;mid=2649983720&amp;idx=2&amp;sn=4f84e9cd7643835604c6512ed01d7620&amp;scene=21#wechat_redirect\" target=\"_blank\" style=\"text-decoration: underline;font-size: 15px;color: rgb(0, 112, 192);\" ><span style=\"font-size: 15px;color: rgb(0, 112, 192);\">\u7a81\u7834\u6027\u533b\u7597\u5668\u68b0\u8ba4\u5b9a<\/span><\/a><span style=\"font-size: 15px;\">\u3002\u800c\u5728ASCO\u5e74\u4f1a\u4e0a\uff0c\u8be5\u516c\u53f8\u5c06\u516c\u5e03\u4f7f\u7528\u7532\u57fa\u5316\u6280\u672f\u4f18\u5316\u7684NGS\u6db2\u4f53\u6d3b\u68c0\u6d4b\u8bd5\u5728\u68c0\u6d4b\u764c\u75c7\u5e76\u4e14\u5224\u65ad\u5176\u7ec4\u7ec7\u8d77\u6e90\u65b9\u9762\u7684\u8868\u73b0\u3002\u6839\u636e\u5df2\u7ecf\u516c\u5e03\u7684\u6458\u8981\uff0c<strong>\u8fd9\u4e00\u6db2\u4f53\u6d3b\u68c0\u5728166\u540d\u60a3\u8005\u7684\u8840\u6837\u4e2d\u80fd\u591f\u4ee587%\u7684\u51c6\u786e\u6027\u5224\u65ad\u51fa\u80bf\u7624\u7684\u7ec4\u7ec7\u8d77\u6e90\u3002\u5224\u65ad\u4e73\u817a\u764c\u7684\u51c6\u786e\u7387\u8fbe\u523096%\uff0c\u80ba\u764c\u4e3a88%\uff0c\u809d\u764c\u4e3a90%\uff0c\u80f0\u817a\u764c\u4e3a100%\u3002<\/strong><\/span><\/p>\n<p style=\"line-height: 1.75em;\"><br  \/><\/p>\n<p style=\"line-height: 1.75em;\"><span style=\"font-size: 15px;\">GRAIL\u516c\u5e03\u7684\u53e6\u4e00\u9879\u6570\u636e\u5206\u6790\u8868\u660e\u8be5\u516c\u53f8\u5f00\u53d1\u7684\u6db2\u4f53\u6d3b\u68c0\u6d4b\u8bd5\u80fd\u591f\u4f5c\u4e3a\u9884\u6d4b\u764c\u75c7\u60a3\u8005\u9884\u540e\u7684\u6307\u6807\u3002\u88ab\u7532\u57fa\u5316\u6280\u672f\u53d1\u73b0\u7684\u764c\u75c7\u60a3\u8005\u5728\u968f\u540e\u81f3\u5c11\u4e00\u5e74\u7684\u968f\u8bbf\u4e2d\uff0c\u6b7b\u4ea1\u98ce\u9669\u662f\u672a\u88ab\u8fd9\u4e00\u6280\u672f\u53d1\u73b0\u7684\u764c\u75c7\u60a3\u8005\u76843\u500d\uff08HR=3.0\uff0cp&lt;0.001\uff09\u3002\u8fd9\u610f\u5473\u7740<strong>GRAIL\u7684\u7532\u57fa\u5316\u6280\u672f\u53ef\u4ee5\u53d1\u73b0\u66f4\u9700\u8981\u7acb\u5373\u63a5\u53d7\u6cbb\u7597\u7684\u764c\u75c7\u60a3\u8005<\/strong>\u3002<\/span><\/p>\n<p style=\"line-height: 1.75em;\"><span style=\"font-size: 15px;\"><br  \/><\/span><\/p>\n<p style=\"line-height: 1.75em;\"><span style=\"font-size: 15px;\"><span style=\"font-size: 15px;\">\u5728ASCO\u5927\u4f1a\u4e0a\uff0cGRAIL\u516c\u53f8\u5c06\u516c\u5e03\u7532\u57fa\u5316\u6280\u672f\u4f18\u5316\u7684NGS\u68c0\u6d4b\u65b9\u6cd5\u5728\u66f4\u5927\u60a3\u8005\u7fa4\u4e2d\u7684\u8868\u73b0\uff0c\u8ba9\u6211\u4eec\u62ed\u76ee\u4ee5\u5f85\u3002<\/span><\/span><\/p>\n<p style=\"line-height: 1.75em;\"><span style=\"font-size: 15px;\"><span style=\"font-size: 15px;\"><br  \/><\/span><\/span><\/p>\n<p style=\"line-height: 1.75em;\"><span style=\"font-size: 15px;\">\u5fae\u4fe1\u56e2\u961f\u5c06\u5bc6\u5207\u5173\u6ce8\u5e76\u4e14\u4e3a\u60a8\u4eec\u62a5\u9053ASCO\u5e74\u4f1a\u7684\u6700\u65b0\u52a8\u6001\uff0c\u656c\u8bf7\u5173\u6ce8\u3002<\/span><\/p>\n<p><br  \/><\/p>\n<p style=\"line-height: normal;\"><span style=\"font-size: 10px;color: rgb(178, 178, 178);\">\u53c2\u8003\u8d44\u6599\uff1a<\/span><\/p>\n<p style=\"line-height: normal;\"><span style=\"font-size: 10px;color: rgb(178, 178, 178);\">[1] Amgen Showcases Oncology Pipeline At ASCO 2019. Retrieved May 15, 2019, from https:\/\/www.amgen.com\/media\/news-releases\/2019\/05\/amgen-showcases-oncology-pipeline-at-asco-2019\/<\/span><\/p>\n<p style=\"line-height: normal;\"><span style=\"font-size: 10px;color: rgb(178, 178, 178);\">[2] ASCO 2019 \u2013 Abstract drop fires the starting gun. Retrieved May 15, 2019, from https:\/\/www.evaluate.com\/vantage\/articles\/news\/trial-results\/asco-2019-abstract-drop-fires-starting-gun<\/span><\/p>\n<p style=\"line-height: normal;\"><span style=\"font-size: 10px;color: rgb(178, 178, 178);\">[3] Roche&#8217;s Gene-Targeting Drug Shows Promise in Child Brain Tumors. Retrieved May 15, 2019, from&nbsp; https:\/\/www.bloomberg.com\/news\/articles\/2019-05-15\/roche-s-gene-targeting-drug-shows-promise-in-child-brain-tumors<\/span><\/p>\n<p style=\"line-height: normal;\"><span style=\"font-size: 10px;color: rgb(178, 178, 178);\">[4] GRAIL Announces Promising New Data with Early Detection Blood Test to be Presented at 2019 American Society of Clinical Oncology Annual Meetinghttps:\/\/grail.com\/press-releases\/grail-announces-promising-new-data-with-early-detection-blood-test-to-be-presented-at-2019-american-society-of-clinical-oncology-annual-meeting\/<\/span><\/p>\n<p style=\"line-height: normal;\"><span style=\"font-size: 10px;color: rgb(178, 178, 178);\">[5] Genome-wide cell-free DNA (cfDNA) methylation signatures and effect on tissue of origin (TOO) performance. Retrieved May 15, 2019, from http:\/\/abstracts.asco.org\/239\/AbstView_239_265539.html<\/span><\/p>\n<p style=\"line-height: normal;\"><span style=\"font-size: 10px;color: rgb(178, 178, 178);\">[6] MacroGenics Announces Positive Results from Phase 3 SOPHIA Study of Margetuximab in Patients with HER2-Positive Metastatic Breast Cancer. Retrieved May 16, 2019, from https:\/\/seekingalpha.com\/pr\/17514356-macrogenics-announces-positive-results-phase-3-sophia-study-margetuximab-patients-her2<\/span><\/p>\n<p style=\"line-height: normal;\"><span style=\"font-size: 10px;color: rgb(178, 178, 178);\">[7] Iovance Biotherapeutics Announces Updates to Tumor Infiltrating Lymphocyte (TIL) Therapy Clinical Programs https:\/\/finance.yahoo.com\/news\/iovance-biotherapeutics-announces-updates-tumor-212743671.html<\/span><\/p>\n<p style=\"line-height: normal;\"><span style=\"font-size: 10px;color: rgb(178, 178, 178);\">[8] Forty Seven, Inc. to Present Initial Safety and Efficacy Data from Phase 1b Clinical Trial of 5F9 in Patients with Acute Myeloid Leukemia and Myelodysplastic Syndrome at 2019 ASCO Annual Meeting. Retrieved May 16, 2019, from https:\/\/ir.fortyseveninc.com\/news-releases\/news-release-details\/forty-seven-inc-present-initial-safety-and-efficacy-data-phase<\/span><\/p>\n<p style=\"line-height: normal;\"><span style=\"font-size: 10px;color: rgb(178, 178, 178);\"><br  \/><\/span><\/p>\n<p style=\"white-space: normal;color: rgb(51, 51, 51);font-family: -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;font-size: 17px;letter-spacing: 0.544px;text-align: justify;background-color: rgb(255, 255, 255);line-height: normal;\"><span style=\"font-size: 10px;color: rgb(178, 178, 178);\">\u672c\u6587\u6765\u81ea\u5fae\u4fe1\u56e2\u961f\uff0c\u6b22\u8fce\u8f6c\u53d1\u5230\u670b\u53cb\u5708\uff0c\u8c22\u7edd\u8f6c\u8f7d\u5230\u5176\u4ed6\u5e73\u53f0\uff1b\u5982\u6709\u5f00\u8bbe\u767d\u540d\u5355\u9700\u6c42\uff0c\u8bf7\u5728\u6587\u7ae0\u5e95\u90e8\u7559\u8a00\uff1b\u5982\u6709\u5176\u4ed6\u5408\u4f5c\u9700\u6c42\uff0c\u8bf7\u8054\u7cfbwuxi_media@wuxiapptec.com<\/span><\/p>\n<p style=\"white-space: normal;text-align: center;\"><br  \/><\/p>\n<p style=\"white-space: normal;text-align: center;\"><img class=\"__bg_gif\"      style=\"color: rgb(51, 51, 51);font-family: -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;font-size: 17px;letter-spacing: 0.544px;white-space: normal;background-color: rgb(255, 255, 255);text-align: center;box-sizing: border-box !important;overflow-wrap: break-word !important;visibility: visible !important;width: 640px !important;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2019\/05\/6-1558315606.gif\" alt=\"ASCO\u6700\u65b0\u6458\u8981\u7cbe\u9009\uff0c\u8fd9\u4e9b\u7814\u7a76\u8fdb\u5c55\u4f60\u90fd\u77e5\u9053\u5417\uff1f\" title=\"ASCO\u6700\u65b0\u6458\u8981\u7cbe\u9009\uff0c\u8fd9\u4e9b\u7814\u7a76\u8fdb\u5c55\u4f60\u90fd\u77e5\u9053\u5417\uff1f\"  \/><\/p>\n<\/p><\/div>\n","protected":false},"excerpt":{"rendered":"<p>\u258e\u836f\u660e\u5eb7\u5fb7\/\u62a5\u9053 \u7f8e\u56fd\u4e34\u5e8a\u80bf\u7624\u5b66\u4f1a\uff08ASCO\uff092019\u5e74\u4f1a\u5373\u5c06\u4e8e5\u670831\u65e5-6\u67084\u65e5\u5728\u7f8e\u56fd\u829d\u52a0\u54e5\u53ec\u5f00\u3002\u8fd9\u662f\u4e16\u754c [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":111785,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[1],"tags":[],"_links":{"self":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/111784"}],"collection":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/comments?post=111784"}],"version-history":[{"count":1,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/111784\/revisions"}],"predecessor-version":[{"id":111795,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/111784\/revisions\/111795"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/media\/111785"}],"wp:attachment":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/media?parent=111784"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/categories?post=111784"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/tags?post=111784"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}