{"id":112171,"date":"2019-05-17T00:00:50","date_gmt":"2019-05-20T01:29:42","guid":{"rendered":"http:\/\/www.05921.net\/index.php\/112171\/"},"modified":"2019-05-20T09:29:45","modified_gmt":"2019-05-20T01:29:45","slug":"1935eff980","status":"publish","type":"post","link":"https:\/\/www.05921.net\/index.php\/112171\/","title":{"rendered":"2018\u5e74\u5168\u7403\u6297\u80bf\u7624\u9886\u57df\u4ea4\u6613\u8d8b\u52bf"},"content":{"rendered":"<div class=\"bpp-post-content\">\n<p style=\"text-align: justify;line-height: 1.5em;\"><span style=\"font-size: 14px;\">\u672c\u6587\u8f6c\u81ea\u79d1\u777f\u552f\u5b89\u58f0\u660e\u79d1\u5b66\u4e0e\u5236\u836f\uff0c\u8f6c\u8f7d\u5df2\u83b7\u6388\u6743\u3002<\/span><\/p>\n<p style=\"text-align: justify;line-height: 1.5em;\"><span style=\"font-size: 14px;\"><br  \/><\/span><\/p>\n<p style=\"font-size: 16px;letter-spacing: 1px;text-align: left;white-space: normal;max-width: 100%;box-sizing: border-box;min-height: 1em;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;box-sizing: border-box;font-size: 14px;color: rgb(26, 198, 4);overflow-wrap: break-word !important;\">\u539f\u6587<span style=\"max-width: 100%;box-sizing: border-box;letter-spacing: 0px;overflow-wrap: break-word !important;\">\u4f5c\u8005\uff1aJamie Munro &amp; Helen Dowden\uff0c<\/span><\/span><\/p>\n<p style=\"font-size: 16px;letter-spacing: 1px;text-align: left;white-space: normal;max-width: 100%;box-sizing: border-box;min-height: 1em;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 14px;color: rgb(136, 136, 136);box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u79d1\u777f\u552f\u5b89\u751f\u547d\u79d1\u5b66\u54a8\u8be2\u670d\u52a1\u56e2\u961f<\/span><\/p>\n<hr style=\"font-size: 16px;letter-spacing: 1px;text-align: left;white-space: normal;max-width: 100%;border-style: solid;border-right-width: 0px;border-bottom-width: 0px;border-left-width: 0px;border-color: rgba(0, 0, 0, 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border-box;min-height: 1em;white-space: normal;overflow-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\"  \/><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section  style=\"max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box;font-size: 15px;text-align: left;line-height: 1.8;letter-spacing: 1px;overflow-wrap: break-word !important;\">\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;overflow-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u6574\u4f53\u6765\u770b\uff0c2018\u5e74\u7684\u4ea4\u6613\u6709\u4e09\u5927\u7279\u70b9\uff1a<\/strong><\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;overflow-wrap: 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!important;\">\u5f53\u7136\uff0c\u51e1\u4e8b\u90fd\u6709\u4f8b\u5916\uff0c2017\u5e74\uff0c\u9ed8\u514b\u4e0e\u963f\u65af\u5229\u5eb7\u5c31PARP\u6291\u5236\u5242\u5965\u62c9\u5e15\u5c3c\uff08Lynparza\uff09\u5171\u540c\u5f00\u53d1\u53ca\u5546\u4e1a\u5316\u8fbe\u6210\u4e00\u7b14\u91cd\u78c5\u4ea4\u6613\uff0c\u524d\u8005\u652f\u4ed8\u540e\u8005\u7684\u9996\u4ed8\u6b3e\u5c31\u9ad8\u8fbe16\u4ebf\u7f8e\u91d1\uff0c\u8be5\u4ea4\u6613\u4e5f\u5237\u65b0\u4e86\u8fc7\u53bb5\u5e74\u4ea4\u6613\u9996\u4ed8\u6b3e\u7684\u8bb0\u5f55\u3002<\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;overflow-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;overflow-wrap: break-word !important;\">\u53bb\u5e74\u7684\u4e00\u7bc7\u9898\u4e3a\u300aBioPharma Dealmakers B3\u2013B6, March 2018\u300b\u7684\u5206\u6790\u62a5\u544a\u663e\u793a\uff0c\u56f4\u7ed5\u80bf\u7624\u514d\u75ab\u7684\u8bb8\u53ef\u4ea4\u6613\u5728\u8fc7\u53bb5\u5e74\u5360\u4e3b\u5bfc\u5730\u4f4d\uff0c2018\u5e74\u7ee7\u627f\u4e86\u8fd9\u4e00\u8d8b\u52bf\uff0c\u80bf\u7624\u514d\u75ab\u9886\u57df\u7684\u4ea4\u6613\u603b\u989d\u8d85\u8fc710\u4ebf\u7f8e\u5143\uff08\u88681\uff09\uff1a\u8fd9\u4e9b\u4ea4\u6613\u4e2d\uff0c\u53ea\u6709\u4e24\u7b14\u4ea4\u6613\u4ee5\u5df2\u4e0a\u5e02\u9879\u76ee\u4e3a\u6807\u7684\uff08\u9ed8\u514b\u4e0e\u536b\u6750\u3001BMS\u548cNektar\uff0c\u5747\u56f4\u7ed5PD-1\u65b0\u7684\u8054\u5408\u7528\u836f\u5f00\u5c55\uff09\uff0c\u5176\u5b83\u9ad8\u4ef7\u503c\u7684\u4ea4\u6613\u9879\u76ee\u5927\u591a\u5904\u4e8e\u836f\u7269\u53d1\u73b0\u53ca\u4e34\u5e8a\u524d\u7b49\u65e9\u671f\u7814\u7a76\u9636\u6bb5\u3002<\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;overflow-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;color: rgb(61, 167, 66);box-sizing: border-box !important;overflow-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u9664\u4e86\u80bf\u7624\u514d\u75ab\u5904\u4e8e\u4f18\u52bf\u5730\u4f4d\u4ee5\u5916\uff0c\u56f4\u7ed5\u80bf\u7624\u9886\u57df\u7684\u5408\u4f5c\u4ea4\u6613\u8fd8\u6709\u4e24\u5927\u8d8b\u52bf\uff1a<\/strong><\/span><\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;color: rgb(61, 167, 66);box-sizing: border-box !important;overflow-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">1\u3001\u5c06\u521b\u65b0\u6297\u80bf\u7624\u836f\u5f15\u5165\u4e1c\u4e9a\u5e02\u573a\u5c24\u5176\u662f\u4e2d\u56fd\u7684\u4ea4\u6613\u8d8a\u6765\u8d8a\u591a\u3002<\/strong><\/span><\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;color: rgb(61, 167, 66);box-sizing: border-box !important;overflow-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">2\u3001\u56f4\u7ed5\u65b0\u6280\u672f\u5e73\u53f0\u5f00\u5c55\u7684\u4ea4\u6613\u8d8a\u6765\u8d8a\u591a\u3002<\/strong><\/span><\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;overflow-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\"  \/><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section  style=\"max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box;letter-spacing: 1px;overflow-wrap: break-word !important;\">\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;text-align: center;overflow-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;box-sizing: border-box;color: rgb(104, 23, 255);overflow-wrap: break-word !important;\">\u88681&nbsp; 2018\u5e74\u91d1\u989d\u8d85\u8fc710\u4ebf\u7f8e\u91d1\u7684\u8bb8\u53ef\u4ea4\u6613<\/span><\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section  style=\"max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\">\n<section style=\"margin-top: 10px;margin-bottom: 10px;max-width: 100%;box-sizing: border-box;text-align: center;overflow-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box;vertical-align: middle;display: inline-block;line-height: 0;overflow-wrap: break-word !important;\"><img class=\"\"          style=\"box-sizing: border-box;vertical-align: middle;overflow-wrap: break-word !important;width: 556px !important;visibility: visible !important;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2019\/05\/3-1558315783.jpg\" alt=\"2018\u5e74\u5168\u7403\u6297\u80bf\u7624\u9886\u57df\u4ea4\u6613\u8d8b\u52bf\" title=\"2018\u5e74\u5168\u7403\u6297\u80bf\u7624\u9886\u57df\u4ea4\u6613\u8d8b\u52bf\"  \/><\/section>\n<\/section>\n<\/section>\n<section  style=\"max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\">\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;white-space: normal;overflow-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\"  \/><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section  style=\"max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\">\n<section style=\"margin-top: 10px;margin-bottom: 10px;max-width: 100%;box-sizing: border-box;text-align: center;overflow-wrap: break-word !important;\">\n<section style=\"padding-right: 10px;padding-left: 10px;max-width: 100%;box-sizing: border-box;display: inline-block;vertical-align: top;overflow-wrap: break-word !important;\">\n<section style=\"margin-left: -10px;max-width: 100%;box-sizing: border-box;display: inline-block;vertical-align: middle;width: 10px;border-top: 1px solid rgb(26, 198, 4);border-right-color: rgb(26, 198, 4);border-bottom-color: rgb(26, 198, 4);border-left-color: rgb(26, 198, 4);overflow-wrap: break-word !important;\"><\/section>\n<section style=\"padding-right: 5px;padding-left: 5px;max-width: 100%;box-sizing: border-box;display: inline-block;vertical-align: middle;color: rgb(104, 23, 255);overflow-wrap: break-word !important;\">\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;overflow-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u4e2d\u56fd\u589e\u957f<\/strong><\/p>\n<\/section>\n<section style=\"margin-right: -10px;max-width: 100%;box-sizing: border-box;display: inline-block;vertical-align: middle;width: 10px;border-top: 1px solid rgb(26, 198, 4);border-right-color: rgb(26, 198, 4);border-bottom-color: rgb(26, 198, 4);border-left-color: rgb(26, 198, 4);overflow-wrap: break-word !important;\"><\/section>\n<\/section>\n<\/section>\n<\/section>\n<section  style=\"max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box;text-align: left;font-size: 15px;line-height: 1.8;letter-spacing: 1px;overflow-wrap: break-word !important;\">\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;overflow-wrap: break-word !important;\">\u8fc7\u53bb\u51e0\u5e74\uff0c\u5728\u4e00\u7cfb\u5217\u653f\u7b56\u6cd5\u89c4\u6539\u9769\u7684\u63a8\u52a8\u4e0b\uff0c\u4e2d\u56fd\u751f\u7269\u533b\u53d1\u73af\u5883\u548c\u521b\u65b0\u836f\u5e02\u573a\u53d1\u751f\u4e86\u91cd\u5927\u7684\u53d8\u5316\u300aNat. Rev. Drug Discov. 17, 858\u2013859; 2018\u300b\u3002\u4e2d\u56fd\u5e02\u573a\u7684\u4e00\u4e2a\u5173\u952e\u7279\u5f81\u662f\u7f3a\u4e4f\u6700\u65b0\u4e00\u4ee3\u6297\u80bf\u7624\u836f\u7269\u2014\u2014\u5c24\u5176\u662f\u4ee5PD-1\u836f\u7269\u4e3a\u4ee3\u8868\u7684\u751f\u7269\u836f\u3002\u57fa\u4e8e\u6b64\uff0c\u4ece\u80bf\u7624\u9886\u57df\u7684\u4ea4\u6613\u89d2\u5ea6\u770b\uff0c\u9488\u5bf9\u4e1c\u4e9a\u5e02\u573a\uff0c\u8d8a\u6765\u8d8a\u591a\u7684\u4e2d\u56fd\u672c\u571f\u516c\u53f8\u79ef\u6781\u4ece\u5916\u8d44\u4f01\u4e1a\u83b7\u53d6\u521b\u65b0\u836f\u7684\u5f00\u53d1\u6743\u548c\u9500\u552e\u6743\uff08\u56fe2\uff09\u3002\u5c3d\u7ba1\u8fd9\u4e9b\u4ea4\u6613\u7684\u6570\u91cf\u548c\u91d1\u989d\u76f8\u5bf9\u8f83\u5c0f\uff0c\u4f46\u4e2d\u56fd\u533b\u836f\u884c\u4e1a\u7684\u5feb\u901f\u53d1\u5c55\u5c06\u6781\u5927\u63a8\u8fdb\u6b64\u7c7b\u4ea4\u6613\u7684\u589e\u957f\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n<section  style=\"max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\">\n<section style=\"margin-top: 10px;margin-bottom: 10px;max-width: 100%;box-sizing: border-box;text-align: center;overflow-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box;vertical-align: middle;display: inline-block;line-height: 0;overflow-wrap: break-word !important;\"><img class=\"\"          style=\"box-sizing: border-box;vertical-align: middle;overflow-wrap: break-word !important;width: 511px !important;visibility: visible !important;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2019\/05\/8-1558315783.jpg\" alt=\"2018\u5e74\u5168\u7403\u6297\u80bf\u7624\u9886\u57df\u4ea4\u6613\u8d8b\u52bf\" title=\"2018\u5e74\u5168\u7403\u6297\u80bf\u7624\u9886\u57df\u4ea4\u6613\u8d8b\u52bf\"  \/><\/section>\n<\/section>\n<\/section>\n<section  style=\"max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box;font-size: 14px;color: rgb(104, 23, 255);letter-spacing: 1px;text-align: left;overflow-wrap: break-word !important;\">\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;overflow-wrap: break-word !important;\">\u56fe2\u3001\u4e2d\u56fd\u516c\u53f8\u4f5c\u4e3a\u4e70\u65b9\u7684\u6297\u80bf\u7624\u9886\u57df\u7684\u8bb8\u53ef\u4ea4\u6613\uff0c\u6709\u5173\u6570\u636e\u96c6\u7684\u8be6\u7ec6\u4fe1\u606f\uff0c\u8bf7\u53c2\u89c1&nbsp;Box 1\u3002<\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;overflow-wrap: break-word !important;\"><br  \/><\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;overflow-wrap: break-word !important;\">\u8fd9\u4e9b\u4ea4\u6613\u4e2d\uff0c\u6bd4\u8f83\u8457\u540d\u7684\u6848\u4f8b\u6709\uff1a<\/p>\n<\/section>\n<\/section>\n<\/section>\n<section  style=\"max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box;text-align: left;font-size: 15px;line-height: 1.8;letter-spacing: 1px;overflow-wrap: break-word !important;\">\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;overflow-wrap: break-word !important;\">2018\u5e7411\u6708\uff0c\u767e\u6d4e\u795e\u5dde\u4e0e\u52a0\u62ff\u5927Zymeworks\u516c\u53f8\u5408\u4f5c\uff0c\u767e\u6d4e\u795e\u5dde\u83b7\u5f97 Zymeworks \u5904\u4e8e\u4e34\u5e8a\u9636\u6bb5\u7684\u53cc\u7279\u5f02\u6027\u6297\u4f53\u5019\u9009\u836f\u7269ZW25\uff0c\u4ee5\u53ca\u5904\u4e8e\u4e34\u5e8a\u524d\u9636\u6bb5\u7684\u6297\u4f53-\u836f\u7269\u5076\u8054\u7269\uff08ADC\uff09ZW49\u5728\u4e9a\u6d32\uff08\u65e5\u672c\u9664\u5916\uff09\u3001\u6fb3\u5927\u5229\u4e9a\u548c\u65b0\u897f\u5170\u7684\u5f00\u53d1\u548c\u5546\u4e1a\u5316\u7684\u72ec\u5bb6\u6388\u6743\u3002Zymeworks\u5c06\u83b7\u5f974000\u4e07\u7f8e\u5143\u7684\u9884\u4ed8\u6b3e\u548c3.9\u4ebf\u7f8e\u5143\u7684\u5f00\u53d1\u548c\u5546\u4e1a\u5316\u91cc\u7a0b\u91d1\u3002<\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;overflow-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;overflow-wrap: break-word !important;\">2018\u5e746\u6708\uff0c\u603b\u90e8\u4f4d\u4e8e\u82cf\u5dde\u7684\u57fa\u77f3\u836f\u4e1a\u4e0e\u7f8e\u56fdBlueprint Medicines\u5ba3\u5e03\u8fbe\u6210\u72ec\u5bb6\u5408\u4f5c\u53ca\u6388\u6743\u8bb8\u53ef\u534f\u8bae\uff0c\u63a8\u8fdb\u6fc0\u9176\u6291\u5236\u5242avapritinib\u3001BLU-554\u53caBLU-667\u5728\u5927\u4e2d\u534e\u5730\u533a\u7684\u5f00\u53d1\u4e0e\u5546\u4e1a\u5316\u3002Blueprint Medicines\u5c06\u6536\u52304000\u4e07\u7f8e\u5143\u7684\u9884\u4ed8\u6b3e\u548c3.46\u4ebf\u7f8e\u5143\u7684\u91cc\u7a0b\u91d1\u3002\u540c\u6708\uff0c\u57fa\u77f3\u836f\u4e1a\u4e0eAgios\u516c\u53f8\u7b7e\u7f72\u72ec\u5bb6\u8bb8\u53ef\u534f\u8bae\uff0c\u83b7\u5f97ivosidenib\u5728\u4e2d\u56fd\u5927\u9646\u3001\u9999\u6e2f\u3001\u6fb3\u95e8\u548c\u53f0\u6e7e\u7684\u5f00\u53d1\u548c\u5546\u4e1a\u5316\u6743\u529b\uff08ivosidenib\u4e3a\u6cbb\u7597\u6025\u6027\u9ad3\u7ec6\u80de\u767d\u8840\u75c5\u548c\u80c6\u7ba1\u764c\u7684\u836f\u7269\uff0c\u76ee\u524d\u5df2\u5728\u7f8e\u56fd\u5df2\u4e0a\u5e02\uff0c\u5546\u54c1\u540d\u4e3aTibsovo\uff09\u3002\u4f5c\u4e3a\u534f\u8bae\u7684\u4e00\u90e8\u5206\uff0cAgios\u5c06\u83b7\u5f971200\u4e07\u7f8e\u5143\u7684\u9884\u4ed8\u6b3e\u548c4.12\u4ebf\u7f8e\u5143\u7684\u91cc\u7a0b\u91d1\u3002<\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;overflow-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;overflow-wrap: break-word !important;\">\u518d\u9f0e\u533b\u836f\u56e0\u6700\u8fd1\u51e0\u5e74\u4e0e\u7f8e\u56fd\u516c\u53f8\u7b7e\u7f72\u7684\u591a\u9879\u534f\u8bae\u800c\u683c\u5916\u5f15\u4eba\u77a9\u76ee\u30022018\u5e7411\u6708\uff0c\u8be5\u516c\u53f8\u4e0eMacro Genics\u5c31\u4e09\u6b3e\u5728\u7814\u4ea7\u54c1\u8fbe\u6210\u6218\u7565\u5408\u4f5c\u534f\u8bae\uff08\u5305\u62ec\u4ee5HER2\u4e3a\u9776\u70b9\u7684\u5355\u514b\u9686\u6297\u4f53margetuximab\uff0c\u4ee5\u53ca\u963b\u65adPD-1\u548cLAG-3\u7684\u53cc\u7279\u5f02\u6027\u5206\u5b50\uff09\uff0c\u83b7\u5f97\u4e86\u4e0a\u8ff0\u4ea7\u54c1\u5728\u4e2d\u56fd\u5927\u9646\u3001\u9999\u6e2f\u3001\u6fb3\u95e8\u548c\u53f0\u6e7e\u5730\u533a\u7684\u5f00\u53d1\u53ca\u5546\u4e1a\u5316\u72ec\u5bb6\u6388\u6743\u3002<\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;overflow-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;overflow-wrap: break-word !important;\">\u4e2d\u56fd\u516c\u53f8\u4e0e\u897f\u65b9\u516c\u53f8\u7684\u5408\u4f5c\u4e00\u65b9\u9762\u52a0\u901f\u4e86\u6d77\u5916\u521b\u65b0\u836f\u7269\u8fdb\u5165\u4e2d\u56fd\u3002\u53e6\u4e00\u65b9\u9762\uff0c\u4e5f\u52a0\u901f\u4e86\u4e2d\u56fd\u539f\u521b\u65b0\u836f\u7684\u5f00\u53d1\u901f\u5ea6\u3002\u6bd4\u5982\uff0c2018\u5e74\u5e95\uff0c\u4fe1\u8fbe\u751f\u7269\u4e0e\u793c\u6765\u516c\u53f8\u5408\u4f5c\u5f00\u53d1\u7684PD-1\u836f\u7269\u8fbe\u4f2f\u8212\uff08\u4fe1\u8fea\u5229\u5355\u6297\u6ce8\u5c04\u6db2\uff09\u83b7NMPA\u6279\u51c6\u7528\u4e8e\u970d\u5947\u91d1\u6dcb\u5df4\u7624\u7684\u6cbb\u7597\uff0c\u6210\u4e3a\u4e2d\u56fd\u5e02\u573a\u4e0a\u7b2c\u4e8c\u4e2a\u56fd\u4ea7PD-1\u836f\u7269\u3002<\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;overflow-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;overflow-wrap: break-word !important;\">\u9664\u4e2d\u56fd\u4ee5\u5916\uff0c\u4e1c\u4e9a\u5176\u4ed6\u56fd\u5bb6\u7684\u5236\u836f\u516c\u53f8\u4e5f\u662f\u4ea4\u6613\u6e38\u620f\u7684\u53c2\u4e0e\u8005\u30022018\u5e7411\u6708\uff0c\u97e9\u56fdLG\u5316\u5b66\u4e0e\u7f8e\u56fd\u516c\u53f8Cue Biopharma\u7b7e\u7f72\u4e86\u4e00\u9879\u534f\u8bae\uff0c\u83b7\u5f97\u540e\u8005\u7684\u6838\u5fc3\u4ea7\u54c1CUE-101\u4ee5\u53ca\u201cT\u7ec6\u80de\u9776\u5411\u80bf\u7624\u514d\u75ab\u7597\u6cd5\u201d\u5728\u4e9a\u6d32\u7684\u5f00\u53d1\u53ca\u5546\u4e1a\u5316\u6743\u529b\u3002\u6839\u636e\u534f\u8bae\uff0cCue Biopharma\u5c06\u83b7\u5f974\u4ebf\u7f8e\u5143\u7684\u7814\u53d1\u91cc\u7a0b\u7891\u91d1\uff0c\u9664\u6b64\u4e4b\u5916\uff0c\u8fd9\u7b14\u4ea4\u6613\u8fd8\u5305\u62ec\u4e00\u7b14\u672a\u62ab\u9732\u7684\u9884\u4ed8\u6b3e\u548c500\u4e07\u7f8e\u5143\u7684\u80a1\u6743\u6295\u8d44\u3002<\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;overflow-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;overflow-wrap: break-word !important;\">\u4e0e\u6b64\u540c\u65f6\uff0c\u4e9a\u592a\u5730\u533a\u7684\u6295\u8d44\u8d44\u672c\u4e5f\u5728\u9010\u6e10\u6210\u719f\u3002\u4f5c\u4e3a\u4e2d\u56fd\u79d1\u6280\u516c\u53f8\u9876\u7ea7\u6295\u8d44\u8005\u7684\u9ad8\u74f4\u8d44\u672c\uff08Hillhouse 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border-box;display: inline-block;vertical-align: top;overflow-wrap: break-word !important;\">\n<section style=\"padding-right: 5px;padding-left: 5px;max-width: 100%;box-sizing: border-box;display: inline-block;vertical-align: middle;color: rgb(104, 23, 255);overflow-wrap: break-word !important;\">\n<section  style=\"max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\">\n<section style=\"margin-top: 10px;margin-bottom: 10px;max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\">\n<section style=\"padding-right: 10px;padding-left: 10px;max-width: 100%;box-sizing: border-box;display: inline-block;vertical-align: top;overflow-wrap: break-word !important;\"><\/section>\n<p><strong style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u65b0\u6280\u672f\u5e73\u53f0\u5f00\u5c55\u7684\u4ea4\u6613\u8d8a\u6765\u8d8a\u591a<\/strong><\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;overflow-wrap: break-word !important;\">\u53bb\u5e74\u7684\u4ea4\u6613\u8d8b\u52bf\u663e\u793a\uff0c\u9664\u4e86\u4e2d\u56fd\u7684\u589e\u957f\u683c\u5916\u62a2\u773c\u4e4b\u5916\uff0c\u56f4\u7ed5\u65b0\u6280\u672f\u5e73\u53f0\u5f00\u5c55\u7684\u4ea4\u6613\u4e5f\u8d8a\u6765\u8d8a\u591a\uff0c\u5c24\u5176\u662fT\u7ec6\u80de\u7597\u6cd5\u3001\u53cc\u7279\u5f02\u6027\u6216\u591a\u4ef7\u6297\u4f53\u3002\u88681\u663e\u793a\uff0c\u5c3d\u7ba1\u5927\u578b\u5236\u836f\u516c\u53f8\u901a\u5e38\u662f\u65b0\u6280\u672f\u7684\u4e70\u5bb6\u3002\u4f46\u5c0f\u578b\u521b\u65b0\u6027\u516c\u53f8\u4e5f\u662f\u4e0d\u5bb9\u5ffd\u89c6\u7684\u529b\u91cf\uff0c\u8fd9\u5176\u4e2d\u6700\u503c\u5f97\u5173\u6ce8\u7684\u5c31\u662fAllogene\u7684\u4ea4\u6613\u30022017\u5e74Gilead\u6536\u8d2dKite\u540e\uff0cKite\u5236\u836f\u7684\u524d\u9ad8\u7ba1Arie Belldegrun\u548cDavid Chang\u521b\u5efa\u4e86Allogene\uff0c\u8be5\u516c\u53f8\u4e3b\u8981\u4e13\u6ce8\u4e8e\u6253\u9020\u201c\u540c\u79cd\u5f02\u4f53\u201d\u7684\u65b0\u4e00\u4ee3\u7684CAR-T\u7597\u6cd5\u30022018\u5e744\u6708\uff0cAllogene\u901a\u8fc7A\u8f6e\u878d\u8d44\u4e2d\u83b7\u5f97\u4e863\u4ebf\u7f8e\u5143\u7684\u5de8\u989d\u8d44\u91d1\uff08\u8f89\u745e\u6301\u6709\u8be5\u516c\u53f825%\u7684\u80a1\u6743\uff09\u3002\u540c\u6708\uff0cAllogene\u4e0eectis\u7b49\u591a\u5bb6\u77e5\u540d\u751f\u7269\u533b\u836f\u516c\u53f8\u8fbe\u6210\u5408\u4f5c\uff0c\u76ee\u6807\u5c31\u662f\u8054\u5408\u591a\u65b9\u529b\u91cf\u5171\u540c\u6253\u9020\u201c\u901a\u7528\u578b\u201dCAR-T\u7597\u6cd5\u3002<\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;overflow-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;overflow-wrap: break-word !important;\">\u4ece\u6280\u672f\u9a71\u52a8\u7684\u7ef4\u5ea6\u6765\u770b\uff0c\u8fd1\u51e0\u5e74\u6765\u8bb8\u53ef\u4ea4\u6613\u6240\u6d89\u53ca\u7684\u6280\u672f\u8868\u660e\uff1a\u4e34\u5e8a\u4ef7\u503c\u3001\u6ce8\u518c\u76d1\u7ba1\u4ee5\u53ca\u5546\u4e1a\u4e0a\u7684\u6210\u529f\u9ad8\u5ea6\u534f\u540c\u3002\u6570\u636e\u663e\u793a\uff0c2018\u5e74\u4ea4\u6613\u7684\u4e3b\u8981\u9a71\u52a8\u56e0\u7d20\u6709\u7ec6\u80de\u7597\u6cd5\u3001\u5be1\u6838\u82f7\u9178\u3001\u4f5c\u4e3a\u514d\u75ab\u523a\u6fc0\u5242\u7684\u5176\u4ed6\u6297\u539f\u7b49\u3002\u76f8\u53cd\uff0c\u5c3d\u7ba1\u56f4\u7ed5\u6297\u4f53\u7684\u4ea4\u6613\u6570\u91cf\u5360\u6240\u6709\u4ea4\u6613\u7684\u4e09\u5206\u4e4b\u4e00\uff0c\u4f46\u5176\u4ea4\u6613\u989d\u7684\u8d21\u732e\u660e\u663e\u4e0b\u964d\uff08\u56fe3\uff09\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n<section  style=\"max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\">\n<section style=\"margin-top: 10px;margin-bottom: 10px;max-width: 100%;box-sizing: border-box;text-align: center;overflow-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box;vertical-align: middle;display: inline-block;line-height: 0;overflow-wrap: break-word !important;\"><img class=\"\"          style=\"box-sizing: border-box;vertical-align: middle;overflow-wrap: break-word !important;width: 556px !important;visibility: visible !important;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2019\/05\/9-1558315784.jpg\" alt=\"2018\u5e74\u5168\u7403\u6297\u80bf\u7624\u9886\u57df\u4ea4\u6613\u8d8b\u52bf\" title=\"2018\u5e74\u5168\u7403\u6297\u80bf\u7624\u9886\u57df\u4ea4\u6613\u8d8b\u52bf\"  \/><\/section>\n<\/section>\n<\/section>\n<section  style=\"max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box;font-size: 14px;color: rgb(104, 23, 255);letter-spacing: 1px;text-align: left;overflow-wrap: break-word !important;\">\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;overflow-wrap: break-word !important;\">\u56fe3\u3001\u80bf\u7624\u9886\u57df\u8bb8\u53ef\u4ea4\u6613\u7684\u6280\u672f\u7c7b\u522b\uff1ba\uff0c\u4ea4\u6613\u6570\u91cf\uff1bb\uff0c\u4ea4\u6613\u91d1\u989d\u3002<\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;overflow-wrap: break-word !important;\">\u6709\u5173\u6570\u636e\u96c6\u7684\u8be6\u7ec6\u4fe1\u606f\uff0c\u8bf7\u53c2\u89c1&nbsp;Box 1\uff0cOligonucleotides<\/p>\n<\/section>\n<\/section>\n<\/section>\n<section  style=\"max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\">\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;white-space: normal;overflow-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\"  \/><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section  style=\"max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box;text-align: left;font-size: 15px;line-height: 1.8;letter-spacing: 1px;overflow-wrap: break-word !important;\">\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;overflow-wrap: break-word !important;\">\u65b0\u7684\u66ff\u4ee3\u6280\u672f\u4e5f\u662f2018\u5e74\u5927\u578b\u5e76\u8d2d\u4ea4\u6613\u7684\u5173\u952e\u9a71\u52a8\u56e0\u7d20\uff08\u88682\uff09\u3002\u5176\u4e2d\uff0c\u9488\u5bf9\u6eb6\u7624\u75c5\u6bd2\u5e73\u53f0\u7684\u4e09\u9879\u6536\u8d2d\uff0c\u4ece\u4fa7\u9762\u4f53\u73b0\u4e86\u5236\u836f\u516c\u53f8\u63a2\u7d22\u65b0\u7684\u6cbb\u7597\u65b9\u5f0f\u4ee5\u671f\u8fbe\u5230\u7cbe\u786e\u6cbb\u7597\u7684\u8feb\u5207\u9700\u6c42\u3002<\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;overflow-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;overflow-wrap: break-word !important;\">2018\u5e74\u91d1\u989d\u6700\u9ad8\u7684\u51e0\u4e2a\u4ea4\u6613\u4e3b\u8981\u96c6\u4e2d\u5728CAR-T\u7ec6\u80de\u6cbb\u7597\u9886\u57df\uff1aJuno\u4f5c\u4e3a\u8be5\u9886\u57df\u7684\u9886\u5934\u7f8a\uff0c\u524d\u51e0\u5e74\u8fdb\u884c\u4e86\u4e00\u7cfb\u5217\u7684\u5e76\u8d2d\uff0c\u5de9\u56fa\u4e86\u5176\u5728CAR-T\u7ec6\u80de\u6cbb\u7597\u9886\u57df\u7684\u6280\u672f\u4f18\u52bf\u3002\u4f462018\u5e74\u521d\uff0cCelgene\u4ee590\u4ebf\u7f8e\u5143\u5c06\u5176\u7eb3\u5165\u9ebe\u4e0b\uff0c\u4ece\u4ea4\u6613\u989d\u6765\u770b\uff0c\u8be5\u4ea4\u6613\u4ec5\u6b21\u4e8e2017\u5e74Gilead \u6536\u8d2dKite\u7684\u90a3\u7b14\u4ea4\u6613\uff08\u4ea4\u6613\u989d119\u4ebf\u7f8e\u5143\uff09\u3002<\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;overflow-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;overflow-wrap: break-word !important;\">\u5728\u4f20\u7edf\u80bf\u7624\u9886\u57df\uff0c\u845b\u5170\u7d20\u53f2\u514b\u4ee5\u7565\u9ad8\u4e8e50\u4ebf\u7f8e\u5143\u7684\u4ef7\u683c\u6536\u8d2d\u4e86Tesaro\uff0c\u6210\u4e86\u4f20\u7edf\u80bf\u7624\u9886\u57df\u552f\u4e00\u5b97\u4ef7\u503c\u6570\u5341\u4ebf\u7f8e\u5143\u7684\u5e76\u8d2d\u6848\u3002Tesaro\u7684\u4ea7\u54c1\u7ec4\u5408\u5305\u62ec\u6700\u8fd1\u6279\u51c6\u7684PARP\u6291\u5236\u5242Zejula\uff08niraparib\uff09\uff0c\u4ee5\u53ca\u4e00\u4e9b\u5305\u62ecPD-1\u5728\u5185\u7684\uff0c\u5904\u4e8e\u65e9\u671f\u4e34\u5e8a\u9636\u6bb5\u7684\u80bf\u7624\u514d\u75ab\u7c7b\u836f\u7269\u3002<\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;overflow-wrap: break-word !important;\">2018\u5e74\uff0c\u793c\u6765\u516c\u53f8\u65a5\u8d4416\u4ebf\u7f8e\u5143\u6536\u8d2d\u4e86ARMO BioScience\uff0c\u5c06\u540e\u8005\u5904\u4e8e\u80f0\u817a\u764cIII\u671f\u4e34\u5e8a\u7684\u805a\u4e59\u4e8c\u9187\u767d\u4ecb\u7d20-10\u5019\u9009\u7269\u7eb3\u5165\u9ebe\u4e0b\u30022019\u5e74\u5e74\u521d\uff0c\u8be5\u516c\u53f8\u53c8\u53d1\u52a8\u4e86\u91d1\u989d\u66f4\u5927\u7684\u4e00\u7b14\u6536\u8d2d\uff0c\u4ee580\u4ebf\u7f8e\u5143\u7684\u4ef7\u683c\u6536\u8d2d\u4e86Loxo\u80bf\u7624\u516c\u53f8\uff08\u8be5\u516c\u53f8\u4e13\u6ce8\u4e8e\u5f00\u53d1\u57fa\u4e8e\u7279\u5b9a\u9057\u4f20\u7f3a\u9677\u7684\u80bf\u7624\u6cbb\u7597\u836f\u7269\uff09\u3002<\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;overflow-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;overflow-wrap: break-word !important;\">2017\u5e745\u6708\uff0c\u9ed8\u514b\u7684PD-1\u836f\u7269Keytruda\u4ec5\u57fa\u4e8e\u57fa\u56e0\u751f\u7269\u6807\u8bb0\u7684\u5b58\u5728\u800c\u83b7FDA\u8865\u5145\u6279\u51c6\uff08\u9ad8\u5ea6\u5fae\u536b\u661f\u4e0d\u7a33\u5b9a\u6027\u80bf\u7624\uff09\uff0c\u8be5\u4e8b\u4ef6\u5728\u4eba\u7c7b\u7684\u76d1\u7ba1\u53f2\u4e0a\u753b\u4e0a\u4e86\u6d53\u58a8\u91cd\u5f69\u7684\u4e00\u7b14\u3002<\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;overflow-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;overflow-wrap: break-word !important;\">2018\u5e7411\u6708\uff0c\u57fa\u4e8e\u4e00\u9879\u201ctumor-agnostic\u201d\u7684\u5f00\u53d1\u8ba1\u5212\uff0cLoxo\u7684Vitrakvi\uff08larotrectinib\uff09\u6210\u529f\u83b7\u6279\u7528\u4e8e\u6cbb\u7597\u643a\u5e26NTRK\u57fa\u56e0\u878d\u5408\u7684\u6210\u5e74\u548c\u513f\u7ae5\u5c40\u90e8\u665a\u671f\u6216\u8f6c\u79fb\u6027\u5b9e\u4f53\u7624\uff0c\u6210\u4e3aFDA\u6279\u51c6\u7b2c\u4e00\u4e2a\u4e0d\u5206\u764c\u79cd\uff0c\u53ea\u770b\u7a81\u53d8\u7684\u5e7f\u8c31\u6297\u764c\u9776\u5411\u836f\u3002\u800c\u5728\u8fd9\u4e4b\u524d\u76842017\u5e7411\u6708\uff0c\u62dc\u8033\u5c31\u4e0e\u8be5\u516c\u53f8\u8fbe\u6210\u4e00\u9879\u8bb8\u53ef\u534f\u8bae\uff0c\u4ec5\u9996\u4ed8\u6b3e\u5c31\u9ad8\u8fbe4\u4ebf\u7f8e\u91d1\u3002<\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;overflow-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\"  \/><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section  style=\"max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box;color: rgb(104, 23, 255);line-height: 1.8;letter-spacing: 1px;overflow-wrap: break-word !important;\">\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;text-align: center;white-space: normal;overflow-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\">\u88682&nbsp; 2018\u5e74\u91d1\u989d\u8d85\u8fc710\u4ebf\u7f8e\u91d1\u7684\u5e76\u8d2d\u4ea4\u6613<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section  style=\"max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\">\n<section style=\"margin-top: 10px;margin-bottom: 10px;max-width: 100%;box-sizing: border-box;text-align: center;overflow-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box;vertical-align: middle;display: inline-block;line-height: 0;overflow-wrap: break-word !important;\"><img class=\"\"          style=\"box-sizing: border-box;vertical-align: middle;overflow-wrap: break-word !important;width: 556px !important;visibility: visible !important;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2019\/05\/6-1558315784.jpg\" alt=\"2018\u5e74\u5168\u7403\u6297\u80bf\u7624\u9886\u57df\u4ea4\u6613\u8d8b\u52bf\" title=\"2018\u5e74\u5168\u7403\u6297\u80bf\u7624\u9886\u57df\u4ea4\u6613\u8d8b\u52bf\"  \/><\/section>\n<\/section>\n<\/section>\n<section  style=\"max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\">\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;white-space: normal;overflow-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\"  \/><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section  style=\"max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\">\n<section style=\"margin-top: 10px;margin-bottom: 10px;max-width: 100%;box-sizing: border-box;text-align: center;overflow-wrap: break-word !important;\">\n<section style=\"padding-right: 10px;padding-left: 10px;max-width: 100%;box-sizing: border-box;display: inline-block;vertical-align: top;overflow-wrap: break-word !important;\">\n<section style=\"margin-left: -10px;max-width: 100%;box-sizing: border-box;display: inline-block;vertical-align: middle;width: 10px;border-top: 1px solid rgb(26, 198, 4);border-right-color: rgb(26, 198, 4);border-bottom-color: rgb(26, 198, 4);border-left-color: rgb(26, 198, 4);overflow-wrap: break-word !important;\"><\/section>\n<section style=\"padding-right: 5px;padding-left: 5px;max-width: 100%;box-sizing: border-box;display: inline-block;vertical-align: middle;color: rgb(104, 23, 255);overflow-wrap: break-word !important;\">\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;overflow-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u5c55\u671b2019<\/strong><\/p>\n<\/section>\n<section style=\"margin-right: -10px;max-width: 100%;box-sizing: border-box;display: inline-block;vertical-align: middle;width: 10px;border-top: 1px solid rgb(26, 198, 4);border-right-color: rgb(26, 198, 4);border-bottom-color: rgb(26, 198, 4);border-left-color: rgb(26, 198, 4);overflow-wrap: break-word !important;\"><\/section>\n<\/section>\n<\/section>\n<\/section>\n<section  style=\"max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box;font-size: 15px;line-height: 1.8;text-align: left;letter-spacing: 1px;overflow-wrap: break-word !important;\">\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;overflow-wrap: break-word !important;\">2019\u5e74\u521d\uff0c\u5168\u7403\u6392\u540d\u7b2c12\u4f4d\u7684BMS\u5ba3\u5e03\u6536\u8d2d\u6392\u540d\u7b2c21\u4f4dCelgene\uff0c\u8fd9\u7b14\u9ad8\u8fbe740\u4ebf\u7f8e\u5143\u7684\u4ea4\u6613\u5c06\u6781\u5927\u5730\u6269\u5c55BMS\u5df2\u4e0a\u5e02\u836f\u7269\u7684\u6cbb\u7597\u9886\u57df\uff0c\u5c24\u5176\u5728\u8840\u6db2\u80bf\u7624\u548c\u708e\u75c7\u9886\u57df\u3002\u9664\u6b64\u4e4b\u5916\uff0c\u8be5\u5e76\u8d2d\u5c06\u4e3aBMS\u63d0\u4f9b\u4e00\u5927\u6279\u5904\u4e8e\u665a\u671f\u4e34\u5e8a\u7684\u7ba1\u7ebf\u836f\u7269\uff1aluspatercept\uff08\u7528\u4e8e\u9aa8\u9ad3\u589e\u751f\u5f02\u5e38\u7efc\u5408\u5f81\uff09\u3001ozanimod \uff08\u7528\u4e8e\u708e\u75c7\u6027\u75be\u75c5\uff09\u3001bb2121\uff08\u7528\u4e8e\u591a\u53d1\u6027\u9aa8\u9ad3\u7624\uff09\u548cLisocel\uff08\u7528\u4e8e\u6dcb\u5df4\u7624\uff09\u3002<\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;overflow-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;overflow-wrap: break-word !important;\">Celgene\u7684\u4f30\u503c\u6bd4\u4ea4\u6613\u5ba3\u5e03\u524d\u4e00\u5929\u7684\u80a1\u4ef7\u9ad8\u51fa54%\u3002\u5982\u679cCelgene\u7684ozanimod\u3001Lisocel\u548cbb2121\u83b7\u5f97FDA\u6279\u51c6\uff0c\u8d44\u672c\u5e02\u573a\u5c06\u4e00\u6b21\u6027\u5730\u4e3aCelgene\u7684\u80a1\u4e1c\u5e26\u6765\u6bcf\u80a19\u7f8e\u5143\u7684\u56de\u62a5\u3002<\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;overflow-wrap: break-word !important;\">\u7c7b\u4f3c\u6b64\u7c7b\u89c4\u6a21\u7684\u5e76\u8d2d\u63d0\u9ad8\u4e86\u884c\u4e1a\u5bf92019\u5e74\u7684\u5e76\u8d2d\u9884\u671f\u3002<\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;overflow-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;overflow-wrap: break-word !important;\">\u300aBioPharma Dealmakers B3\u2013B6, March 2018\u300b\u663e\u793a\uff0c BMS\u548c\u9ed8\u514b\u57282017\u5e74\u80bf\u7624\u9886\u57df\u4ea4\u6613\u699c\u5355\u4e2d\u540d\u5217\u524d\u8305\u3002\u4f46\u57282018\u5e74\uff0cBMS\u5728\u80bf\u7624\u6cbb\u7597\u9886\u57df\u53ea\u8fdb\u884c\u4e86\u4e00\u7b14\u4ea4\u6613\uff1a\u4e0eNektar\u5c31\u7ecf\u8fc7\u4fee\u9970\u7684IL-2\u5019\u9009\u836f\u7269NKT214\u8fbe\u621036\u4ebf\u7f8e\u5143\u5408\u4f5c\u534f\u8bae\uff08\u88681\uff09\u3002<\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;overflow-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;overflow-wrap: break-word !important;\">\u4ece\u4ea4\u6613\u6570\u91cf\u4e0a\u6765\u770b\uff0c\u9ed8\u514b\u516c\u53f8\u7ee7\u7eed\u4fdd\u6301\u4e86\u6297\u80bf\u7624\u9886\u57df\u7684\u51a0\u519b\u5730\u4f4d\u3002<\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;overflow-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;overflow-wrap: break-word !important;\">Gilead\u5171\u8fdb\u884c\u4e865\u9879\u80bf\u7624\u9886\u57df\u7684\u4ea4\u6613\uff0c\u5176\u4e2d3\u9879\u4ef7\u503c\u8d85\u8fc710\u4ebf\u7f8e\u5143\uff0c\u8fd9\u4ece\u4fa7\u9762\u53cd\u6620\u4e86Gilead\u4ece\u6297\u75c5\u6bd2\u4e1a\u52a1\u5411\u80bf\u7624\u9886\u57df\u62d3\u5c55\u7684\u6218\u7565\u5e03\u5c40\uff08\u56fe4\uff09\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n<section  style=\"max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\">\n<section style=\"margin-top: 10px;margin-bottom: 10px;max-width: 100%;box-sizing: border-box;text-align: center;overflow-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box;vertical-align: middle;display: inline-block;line-height: 0;overflow-wrap: break-word !important;\"><img class=\"\"          style=\"box-sizing: border-box;vertical-align: middle;overflow-wrap: break-word !important;width: 556px !important;visibility: visible !important;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2019\/05\/0-1558315784.jpg\" alt=\"2018\u5e74\u5168\u7403\u6297\u80bf\u7624\u9886\u57df\u4ea4\u6613\u8d8b\u52bf\" title=\"2018\u5e74\u5168\u7403\u6297\u80bf\u7624\u9886\u57df\u4ea4\u6613\u8d8b\u52bf\"  \/><\/section>\n<\/section>\n<\/section>\n<section  style=\"max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box;font-size: 14px;color: rgb(104, 23, 255);overflow-wrap: break-word !important;\">\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;white-space: normal;overflow-wrap: break-word !important;\">\u56fe4\u3001\u5168\u7403\u6392\u540d\u524d30*\u7684\u516c\u53f8\u5728\u80bf\u7624\u9886\u57df\u7684\u4ea4\u6613\u60c5\u51b5\u3002<\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;white-space: normal;overflow-wrap: break-word !important;\">1\u3001\u4ea4\u6613\u65f6\u95f4\uff1a2018\u5e741\u6708-2018\u5e7412\u6708\uff1b<\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;white-space: normal;overflow-wrap: break-word !important;\">2\u3001\u4ea4\u6613\u7c7b\u578b\uff1a\u5e76\u8d2d\u3001\u8bb8\u53ef\u3001\u5408\u8d44\u3001\u5408\u4f5c\u5f00\u53d1\u3001\u8d44\u4ea7\u8f6c\u8ba9\uff1b<\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;white-space: normal;overflow-wrap: break-word !important;\">3*\uff1a\u63092017\u5e74\u8425\u4e1a\u6536\u5165\u6392\u540d\u3002<\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;white-space: normal;overflow-wrap: break-word !important;\">4\u3001\u6392\u540d\u524d30\u4f4d\u7684Valeant\u5236\u836f\u516c\u53f8\u88ab\u6392\u9664\u5728\u5916\uff0c\u56e0\u4e3a\u5b83\u6ca1\u6709\u6267\u884c\u4efb\u4f55\u4e70\u65b9\u4ea4\u6613\u3002<\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;white-space: normal;overflow-wrap: break-word !important;\">\u6709\u5173\u6570\u636e\u96c6\u7684\u8be6\u7ec6\u4fe1\u606f\uff0c\u8bf7\u53c2\u89c1&nbsp;Box 1\u3002<\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;white-space: normal;overflow-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"  \/><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section  style=\"max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box;text-align: left;font-size: 15px;line-height: 1.8;letter-spacing: 1px;overflow-wrap: break-word !important;\">\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;overflow-wrap: break-word !important;\">2018\u5e74\u5927\u591a\u6570\u5927\u578b\u5236\u836f\u516c\u53f8\u5728\u6297\u80bf\u7624\u9886\u57df\u90fd\u5f88\u6d3b\u8dc3\uff1a\u6392\u540d\u524d30\u7684\u5236\u836f\u516c\u53f8\u4e2d\uff0c\u670921\u5bb6\u5728\u6297\u80bf\u7624\u9886\u57df\u81f3\u5c11\u8fdb\u884c\u4e86\u4e00\u7b14\u4ea4\u6613\uff0c\u8fd9\u4e9b\u516c\u53f8\u7684\u4ea4\u6613\u989d\u7ea6\u53602018\u5e74\u6574\u4e2a\u6297\u80bf\u7624\u9886\u57df\u4ea4\u6613\u989d\u768425%\u3002\u4e3b\u8981\u73a9\u5bb6\u7684\u6574\u5408\uff08\u5982BMS\u548cCelgene\uff09\u5728\u524a\u51cf\u8d22\u529b\u96c4\u539a\u4e70\u5bb6\u7684\u540c\u65f6\uff0c\u4e5f\u8981\u6c42\u5176\u4ed6\u53c2\u4e0e\u8005\u52a0\u5927\u5bf9\u6295\u8d44\u7ec4\u5408\u6df1\u5ea6\u548c\u5e7f\u5ea6\u7684\u5e03\u5c40\uff0c\u800c\u8fd9\u65e0\u7591\u7ed9\u8fd9\u4e9b\u53c2\u4e0e\u8005\u5e26\u6765\u4e86\u65b0\u7684\u6311\u6218\u548c\u538b\u529b\u3002<\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;overflow-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;overflow-wrap: break-word !important;\">\u6b64\u5916\uff0c\u88ab\u6536\u8d2d\u516c\u53f8\u80cc\u540e\u7684\u9886\u519b\u4eba\u7269\u4f1a\u7ee7\u7eed\u5efa\u7acb\u65b0\u7684\u521b\u65b0\u578b\u4f01\u4e1a\uff0c\u8fd9\u4e00\u70b9\u4e5f\u662f\u6297\u80bf\u7624\u9886\u57df\u4ea4\u6613\u7684\u53e6\u4e00\u4e2a\u6f5c\u5728\u8d8b\u52bf\u3002<\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;overflow-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\"  \/><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section  style=\"max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\">\n<section style=\"margin-top: 15px;margin-bottom: 15px;max-width: 100%;box-sizing: border-box;text-align: center;overflow-wrap: break-word !important;\">\n<section style=\"padding-right: 10px;padding-bottom: 10px;padding-left: 10px;max-width: 100%;box-sizing: border-box;display: inline-block;vertical-align: top;width: 643.141px;box-shadow: rgb(152, 152, 152) 0px 0px 2px;border-width: 2px 0px 0px;border-radius: 10px;border-style: solid;border-color: rgb(104, 23, 255);background-color: rgb(255, 255, 255);overflow-wrap: break-word !important;\">\n<section  style=\"max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\">\n<section style=\"margin-bottom: 15px;max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\">\n<section style=\"padding-right: 10px;padding-left: 10px;max-width: 100%;box-sizing: border-box;display: inline-block;vertical-align: top;border-bottom-left-radius: 0.5em;border-bottom-right-radius: 0.5em;color: rgb(255, 255, 255);background-color: rgb(104, 23, 255);overflow-wrap: break-word !important;\">\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;overflow-wrap: break-word !important;\">Box 1 | \u6570\u636e\u548c\u65b9\u6cd5\u5b66<\/p>\n<\/section>\n<\/section>\n<\/section>\n<section  style=\"max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box;font-size: 14px;color: rgb(100, 100, 100);text-align: justify;line-height: 1.8;overflow-wrap: break-word !important;\">\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;white-space: normal;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;box-sizing: border-box;letter-spacing: 0px;overflow-wrap: break-word !important;\">1\u3001\u6240\u6709\u6297\u80bf\u7624\u9886\u57df\u4ea4\u6613\u7684\u6570\u636e\u5747\u4eceCortellis\u4e2d\u63d0\u53d6\uff0c\u4ea4\u6613\u65f6\u95f42014\u5e741\u6708\u65e5-2018\u5e7412\u670831\u65e5\u3002<\/span><br style=\"max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;white-space: normal;overflow-wrap: break-word !important;\">2\u3001\u6570\u636e\u5206\u6790\u65f6\uff0c\u9009\u62e9\u4e86\u6536\u8d2d\uff08100%\u6216\u591a\u6570\u80a1\u6743\uff09\u3001\u517c\u5e76\u3001\u53cd\u5411\u517c\u5e76\u3001\u5408\u8d44\u3001\u5355\u7eaf\u7814\u7a76\u548c\u6240\u6709\u201c\u8bb8\u53ef\u201d\u5b50\u7c7b\u578b\u7684\u4ea4\u6613\u8fdb\u884c\u5206\u6790\u3002<\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;white-space: normal;overflow-wrap: break-word !important;\">3\u3001\u83b7\u5f97\u521d\u6b65\u6570\u636e\u540e\uff0c\u4f7f\u7528\u201c\u6280\u672f\u201d\u5206\u7c7b\u5bf9\u751f\u6210\u7684\u6570\u636e\u96c6\u8fdb\u884c\u7b5b\u9009\uff0c\u4ee5\u6392\u9664\u975e\u80bf\u7624\u9886\u57df\u7684\u6cbb\u7597\u6027\u4ea4\u6613\u3002\u6392\u9664\u7684\u201c\u6280\u672f\u201d\u9879\u6709\uff1a\u5206\u6790\u3001\u751f\u7269\u4fe1\u606f\u5b66\u3001\u751f\u7269\u6807\u8bb0\u7269\u3001\u8bca\u65ad\u65b9\u6cd5\u3001\u836f\u7269\u914d\u65b9\u3001\u836f\u7269\u7b5b\u9009\u3001\u4eff\u5236\u836f\u3001\u57fa\u56e0\u7ec4\u6280\u672f\u3001\u6210\u50cf\u3001\u4eea\u5668\u3001\u5b9e\u9a8c\u5ba4\u8bd5\u5242\u3001\u5236\u9020\u3001\u533b\u7597\u548c\u5176\u4ed6\u8bbe\u5907\u3001\u653e\u5c04\u6027\u6807\u8bb0\u3001\u670d\u52a1\u534f\u8bae\u548c\u8f6f\u4ef6\u3002<\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;white-space: normal;overflow-wrap: break-word !important;\">4\u3001\u6240\u6709\u201c\u5f85\u5b9a\u201d\u548c\u201c\u7ec8\u6b62\u201d\u7684\u4ea4\u6613\u4e5f\u88ab\u6392\u9664\u5728\u5916\u3002\u6700\u540e\u6570\u636e\u96c6\u5305\u62ec\u4ee5\u4e0b\u5185\u5bb9\uff1a<\/p>\n<ul class=\"list-paddingleft-2\" style=\"\">\n<li>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;overflow-wrap: break-word !important;\">\u5408\u5e76\u548c\u6536\u8d2d\uff0899\uff09\u3002<\/p>\n<\/li>\n<li>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;overflow-wrap: break-word !important;\">\u8bb8\u53ef\u548c\u5408\u8d44\u4f01\u4e1a\uff081602\uff09\u3002<\/p>\n<\/li>\n<\/ul>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;white-space: normal;overflow-wrap: break-word !important;\">5\u3001\u5728\u8fd91701\u7b14\u4ea4\u6613\u4e2d\uff0c\u53ea\u6709471\u7b14\u4ea4\u6613\u6709\u8d22\u52a1\u7ec6\u8282\u3002<\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;white-space: normal;overflow-wrap: break-word !important;\">6\u3001\u77e9\u9635\u56fe(\u56fe4)\u5305\u62ec\u8d44\u4ea7\u8d2d\u4e70\u3001\u80a1\u6743\u8d2d\u4e70\u548c\u5206\u62c6\u7684\u5176\u4ed6\u4ea4\u6613\u7c7b\u578b\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section  style=\"max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box;text-align: left;font-size: 15px;line-height: 1.8;letter-spacing: 1px;overflow-wrap: break-word !important;\">\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;font-variant-numeric: normal;font-variant-east-asian: normal;line-height: 27px;white-space: normal;widows: 1;background-color: rgb(255, 255, 255);overflow-wrap: break-word !important;\">\u603b\u4e4b\uff0c\u7531\u4e8e\u4e0b\u4e00\u4ee3\u6297\u80bf\u7624\u6280\u672f\u4e34\u5e8a\u9a8c\u8bc1\u7684\u9a71\u52a8\uff0c2018\u5e74\u53c8\u662f\u4e00\u4e2a\u5728\u6297\u80bf\u7624\u9886\u57df\u4ea4\u6613\u5f3a\u52b2\u7684\u4e00\u5e74\uff1a\u4ea4\u6613\u603b\u989d\u663e\u8457\u4e0a\u5347\uff0c\u4e14\u5927\u591a\u9ad8\u989d\u4ea4\u6613\u6807\u7684\u9879\u76ee\u5c1a\u5904\u4e8e\u65e9\u671f\u5f00\u53d1\u9636\u6bb5\uff0c\u8fd9\u4e00\u70b9\u4ece\u4fa7\u9762\u4f53\u73b0\u4e86\u4ee5\u6297\u80bf\u7624\u836f\u4e3a\u6838\u5fc3\u7684\u751f\u7269\u5236\u836f\u516c\u53f8\u5bf9\u65b0\u6280\u672f\u7684\u5f3a\u70c8\u6e34\u671b\u3002<\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;font-variant-numeric: normal;font-variant-east-asian: normal;line-height: 27px;white-space: normal;widows: 1;background-color: rgb(255, 255, 255);overflow-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;font-variant-numeric: normal;font-variant-east-asian: normal;line-height: 27px;white-space: normal;widows: 1;background-color: rgb(255, 255, 255);overflow-wrap: break-word !important;\">\u201c\u80bf\u7624\u514d\u75ab\u201d\u4f9d\u65e7\u662f\u6297\u80bf\u7624\u9886\u57df\u4ea4\u6613\u7684\u5173\u952e\u8bcd\u3002\u9884\u8ba12019\u5e74\uff0c\u80bf\u7624\u9886\u57df\u7684\u5e76\u8d2d\u6d3b\u52a8\u5c06\u7ee7\u7eed\u589e\u52a0\u3002\u4e2d\u56fd\u5bf9\u521b\u65b0\u6297\u80bf\u7624\u521b\u65b0\u836f\u7684\u5f3a\u70c8\u9700\u6c42\uff0c\u4e1a\u5c06\u8fdb\u4e00\u6b65\u63a8\u8fdb\u8be5\u5730\u533a\u6297\u80bf\u7624\u9886\u57df\u4ea4\u6613\u7684\u589e\u957f\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<p style=\"text-align: justify;line-height: 1.5em;\"><span style=\"font-size: 14px;\"><br  \/><\/span><\/p>\n<h2 class=\"\" style=\"margin-top: 10px;margin-bottom: 10px;font-size: 22px;max-width: 100%;letter-spacing: 0.544px;white-space: normal;background-color: rgb(255, 255, 255);line-height: 1.4;text-align: center;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"font-size: 20px;\"><strong><span style=\"max-width: 100%;-webkit-tap-highlight-color: rgba(0, 0, 0, 0);color: rgb(255, 127, 170);box-sizing: border-box !important;overflow-wrap: break-word !important;\"><a href=\"https:\/\/mp.weixin.qq.com\/s?__biz=MzI5ODI5NDE2OA==&amp;mid=2247501032&amp;idx=2&amp;sn=0f6700af84ae8f3aa7df6da6811b0519&amp;chksm=ecaa8a1fdbdd03098fcf9b33f0777e10097ad6fad009fb8befe41da103c37668ce6e3dac0560&amp;mpshare=1&amp;scene=21&amp;srcid=&amp;pass_ticket=cLD9hndLTIy79YwTwMvVrUKoaWTLWUT4c9doEKGoSYB9fkrx3nGRx585ELIKAu6L#wechat_redirect\" target=\"_blank\"  style=\"-webkit-tap-highlight-color: rgba(0, 0, 0, 0);max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u5f81\u7a3f\u542f\u4e8b<\/a><\/span><\/strong><\/span><\/h2>\n<section style=\"max-width: 677px;box-sizing: border-box;white-space: normal;background-color: rgb(255, 255, 255);font-size: 16px;font-family: \u5fae\u8f6f\u96c5\u9ed1;letter-spacing: 0.54px;overflow-wrap: break-word !important;\">\n<section style=\"margin-right: 3px;margin-left: 3px;padding: 20px;max-width: 677px;box-sizing: border-box;background-color: rgb(254, 254, 254);border-color: rgb(210, 150, 20);box-shadow: rgb(210, 150, 20) 0px 0px 4px;overflow-wrap: break-word !important;\">\n<h2 class=\"\" style=\"margin-bottom: 14px;font-size: 22px;max-width: 100%;line-height: 1.4;font-variant-numeric: normal;letter-spacing: 0.544px;text-align: start;widows: 1;background-color: rgb(255, 255, 255);box-sizing: border-box !important;overflow-wrap: break-word !important;\"><a href=\"https:\/\/mp.weixin.qq.com\/s?__biz=MzA5NDk0NTc4MQ==&amp;mid=2650426044&amp;idx=1&amp;sn=c87b281bb6b7baade0105eb459c19ba9&amp;scene=21#wechat_redirect\" target=\"_blank\"  style=\"-webkit-tap-highlight-color: rgba(0, 0, 0, 0);max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;-webkit-tap-highlight-color: rgba(0, 0, 0, 0);font-size: 14px;color: rgb(61, 167, 66);box-sizing: border-box !important;overflow-wrap: break-word !important;\">2019\u836f\u7269\u5206\u79bb\u7eaf\u5316\u548c\u7ed3\u6784\u9274\u5b9a\u53ca\u8d4b\u503c\u6df1\u5ea6\u7814\u8ba8\u4f1a &#8211;CMC\u836f\u7269\u8d28\u91cf\u7cfb\u5217\u7814\u8ba8\u4f1a\u4e4b\u4e09<\/span><\/a><\/h2>\n<p style=\"max-width: 631px;box-sizing: border-box;min-height: 18px;color: rgb(210, 150, 20);font-weight: 700;min-width: 1px;overflow-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box;letter-spacing: 0.54px;color: rgb(51, 51, 51);overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;box-sizing: border-box;color: rgb(214, 168, 65);overflow-wrap: break-word !important;\">\u540c\u5199\u610f\u8bba\u575b\uff1a<\/span><\/strong><\/p>\n<section style=\"margin-top: 10px;margin-bottom: 10px;max-width: 631px;box-sizing: border-box;border-color: rgb(210, 150, 20);overflow-wrap: break-word !important;\">\n<p style=\"margin-bottom: 5px;max-width: 100%;box-sizing: border-box;min-height: 1em;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 14px;box-sizing: border-box !important;overflow-wrap: break-word !important;\">1.<\/span><a href=\"https:\/\/mp.weixin.qq.com\/s?__biz=MzA4MzgzMDM5Mg==&amp;mid=2650628137&amp;idx=1&amp;sn=31a673ec733f84c6eee6873b1fe626c8&amp;scene=21#wechat_redirect\" target=\"_blank\"  style=\"-webkit-tap-highlight-color: rgba(0, 0, 0, 0);max-width: 100%;font-size: 14px;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u5199\u610f\u5de8\u732e\uff1a\u6df1\u5ea6\u89e3\u6790\u4e2d\u7f8e\u52a0\u5feb\u836f\u54c1\u7814\u53d1\u7684\u5ba1\u8bc4\u5ba1\u6279\u653f\u7b56\uff0891\u671f\u65e5\u7a0b\u66f4\u65b0\uff09<\/span><\/a><\/p>\n<p style=\"margin-bottom: 5px;max-width: 100%;box-sizing: border-box;min-height: 1em;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 14px;box-sizing: border-box !important;overflow-wrap: break-word !important;\">2.<\/span><a href=\"https:\/\/mp.weixin.qq.com\/s?__biz=MzA4MzgzMDM5Mg==&amp;mid=2650627699&amp;idx=1&amp;sn=cb1df4a9fd9b4bb1582c9f94d3520f73&amp;scene=21#wechat_redirect\" target=\"_blank\"  style=\"-webkit-tap-highlight-color: rgba(0, 0, 0, 0);max-width: 100%;font-size: 14px;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u7b2c93\u671f\u8bba\u575b\u4e282019\u4e2d\u7f8e\u533b\u7597\u6295\u8d44\u8bba\u575b\u548c\u8def\u6f14<\/span><\/a><\/p>\n<p style=\"margin-bottom: 5px;max-width: 100%;box-sizing: border-box;min-height: 1em;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 14px;box-sizing: border-box !important;overflow-wrap: break-word !important;\">3.<\/span><a href=\"https:\/\/mp.weixin.qq.com\/s?__biz=MzA4MzgzMDM5Mg==&amp;mid=2650628250&amp;idx=2&amp;sn=bbf58c464d6eb350985cf5cf6354af1c&amp;scene=21#wechat_redirect\" target=\"_blank\"  style=\"-webkit-tap-highlight-color: rgba(0, 0, 0, 0);max-width: 100%;font-size: 14px;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u540c\u5199\u610f\u534f\u529e\u4e282019\u7ec6\u80de\u6cbb\u7597\u4ea7\u4e1a\u53d1\u5c55\u6e56\u5317\u5cf0\u4f1a\uff08free\uff09<\/span><\/a><\/p>\n<p style=\"margin-bottom: 5px;max-width: 100%;box-sizing: border-box;min-height: 1em;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 14px;box-sizing: border-box !important;overflow-wrap: break-word !important;\">4.<\/span><a href=\"https:\/\/mp.weixin.qq.com\/s?__biz=MzA4MzgzMDM5Mg==&amp;mid=2650628019&amp;idx=1&amp;sn=5dae65d812e02cc8e74e2a352bbba5d6&amp;scene=21#wechat_redirect\" target=\"_blank\"  style=\"-webkit-tap-highlight-color: rgba(0, 0, 0, 0);max-width: 100%;letter-spacing: 0.54px;font-size: 14px;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;letter-spacing: 0.54px;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u7b2c94\u671f\u8bba\u575b\u4e28\u4eff\u5236\u836f\u9009\u9898\u7acb\u9879\u2014\u7b56\u7565\u4e0e\u65b9\u6cd5<\/span><\/a><\/p>\n<p style=\"margin-bottom: 5px;max-width: 100%;box-sizing: border-box;min-height: 1em;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 14px;box-sizing: border-box !important;overflow-wrap: break-word !important;\">5.<span style=\"max-width: 100%;letter-spacing: 0.54px;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><a href=\"https:\/\/mp.weixin.qq.com\/s?__biz=MzA4MzgzMDM5Mg==&amp;mid=2650628093&amp;idx=1&amp;sn=ce26e32435f63b4eb8b913c510cfb31f&amp;scene=21#wechat_redirect\" target=\"_blank\"  style=\"-webkit-tap-highlight-color: rgba(0, 0, 0, 0);max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u7b2c95\u671f\u8bba\u575b\u4e28BD\u4e2d\u7ea7\u73ed\uff1a\u521b\u65b0\u53d1\u9879\u76ee\u7684\u7efc\u5408\u8bc4\u4f30<\/a><\/span><\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n<p style=\"max-width: 100%;min-height: 1em;letter-spacing: 0.544px;white-space: normal;background-color: rgb(255, 255, 255);box-sizing: border-box !important;overflow-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;letter-spacing: 0.544px;white-space: normal;background-color: rgb(255, 255, 255);text-align: center;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><a href=\"https:\/\/mp.weixin.qq.com\/s?__biz=MzU2MDY5MzA0OQ==&amp;mid=2247484428&amp;idx=1&amp;sn=d7540b3b4d54422e4996085f2bbc0079&amp;chksm=fc056e5acb72e74cec1843e4eb3f9cf04dcf6ea93b9d8448da418734b13b6440111ca014de9a&amp;token=1732418045&amp;lang=zh_CN&amp;scene=21#wechat_redirect\" target=\"_blank\"  style=\"-webkit-tap-highlight-color: rgba(0, 0, 0, 0);max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span class=\"js_jump_icon h5_image_link\"  style=\"max-width: 100%;line-height: 0;top: auto;left: auto;right: auto;bottom: auto;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><img class=\"rich_pages __bg_gif\"        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title=\"2018\u5e74\u5168\u7403\u6297\u80bf\u7624\u9886\u57df\u4ea4\u6613\u8d8b\u52bf\"  \/><br style=\"max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;white-space: normal;background-color: rgb(255, 255, 255);letter-spacing: 0.582857px;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 14px;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u662f\u4e00\u4e2a\u5f00\u653e\uff0c\u7531\u81ea\u613f\u8005\u7ec4\u6210\u7684\u56e2\u4f53\uff0c\u7531\u4ee5\u4e0b\u6210\u5458\u7ec4\u6210\uff1aVoyager88\uff0c\u96f7\u8bfa\u5c9b\uff0cHerman\uff0c\u6885\u5e0c\uff0c\u6587\u7af9\uff0cduke\uff0c\u5360\u5c0f\u5175\uff0c\u9526\u5fc3\u7ee3\u53e3\uff0c\u591a\u5df4\u80fa\uff0c\u745c\u513f\uff0c\u5b50\u708e\uff0c\u514b\u683c\u83ab\uff0cSophia \uff0c\u5076\u9635\u96e8\uff0c\u96f6\u4e0b274\u2103\uff0cHelen\uff0cZMJ\uff0c\u6da6\u513f\uff0c\u7f8a\u7f8a\u3001<span style=\"max-width: 100%;letter-spacing: 0.582857px;box-sizing: border-box !important;overflow-wrap: break-word !important;\">Admiral\u3001<\/span>\u4e8c\u53cb\u6728\u3001\u90ed\u5927\u4fa0\u3001\u8d1d\u58f3\u91cc\u7684\u4e7e\u5764\u548c\u66fe\u6587\u4eae\u3002\u6b22\u8fce\u6709\u5fd7\u4e4b\u58eb\u52a0\u5165\u6211\u4eec\u56e2\u961f\u3002\u6295\u7a3f\u3001\u5408\u4f5c\u3001\u52a0\u4e13\u4e1a\u7fa4\u8bf7\u52a0\u5fae\u4fe1437180999\uff0c\u4e8c\u5343\u4ebaQQ\u7fa422711855\u3002<\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;white-space: normal;background-color: rgb(255, 255, 255);letter-spacing: 0.582857px;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 14px;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><br  \/><\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;white-space: normal;background-color: rgb(255, 255, 255);letter-spacing: 0.582857px;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 14px;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u8d23\u4efb\u7f16\u8f91\uff1a\u96f7\u8bfa\u5c9b<\/span><\/p>\n<\/p><\/div>\n","protected":false},"excerpt":{"rendered":"<p>\u672c\u6587\u8f6c\u81ea\u79d1\u777f\u552f\u5b89\u58f0\u660e\u79d1\u5b66\u4e0e\u5236\u836f\uff0c\u8f6c\u8f7d\u5df2\u83b7\u6388\u6743\u3002 \u539f\u6587\u4f5c\u8005\uff1aJamie Munro &amp; Helen Do [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":112172,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[1],"tags":[],"_links":{"self":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/112171"}],"collection":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/comments?post=112171"}],"version-history":[{"count":1,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/112171\/revisions"}],"predecessor-version":[{"id":112181,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/112171\/revisions\/112181"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/media\/112172"}],"wp:attachment":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/media?parent=112171"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/categories?post=112171"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/tags?post=112171"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}