{"id":112209,"date":"2019-05-17T00:00:50","date_gmt":"2019-05-20T01:29:57","guid":{"rendered":"http:\/\/www.05921.net\/index.php\/112209\/"},"modified":"2019-05-20T09:30:00","modified_gmt":"2019-05-20T01:30:00","slug":"6c5c158f26","status":"publish","type":"post","link":"https:\/\/www.05921.net\/index.php\/112209\/","title":{"rendered":"PNAS\uff1a\u6700\u65b0\u8bc1\u636e\uff01\u201c\u975e\u6574\u500d\u4f53\u201d\u80bf\u7624\u66f4\u5177\u6740\u4f24\u529b\uff01"},"content":{"rendered":"<div class=\"bpp-post-content\">\n<section class=\"xmteditor\" style=\"display:none;\"  ><\/section>\n<p style=\"line-height: 1.75em;\"><span style=\"font-size: 15px;\">\u901a\u5e38\u6765\u8bf4\uff0c\u4eba\u7c7b\u7ec6\u80de\u4e2d\u6b63\u5e38\u542b\u670923\u5bf9\u67d3\u8272\u4f53\uff0c\u4efb\u4f55\u67d3\u8272\u4f53\u6570\u76ee\u7684\u504f\u5dee\u5bf9\u4e8e\u7ec6\u80de\u6765\u8bf4\u90fd\u662f\u81f4\u547d\u7684\u4f24\u5bb3\u3002\u4f17\u6240\u5468\u77e5\u7684\u4e00\u4e9b\u9057\u4f20\u6027\u75be\u75c5\uff0c\u5982\u5510\u6c0f\u7efc\u5408\u75c7\u5c31\u662f\u67d3\u8272\u4f53\u6570\u76ee\u53d8\u5f02\u5f15\u8d77\u7684\u3002\u5728\u7ec6\u80de\u5206\u88c2\u8fc7\u7a0b\u4e2d\uff0c\u67d3\u8272\u4f53\u5206\u9009\u51fa\u73b0\u9519\u8bef\uff0c\u4f1a\u5bfc\u81f4\u975e\u6574\u500d\u6027\u7684\u53d1\u751f\u3002<\/span><\/p>\n<p style=\"line-height: 1.75em;\"><span style=\"font-size: 15px;\">&nbsp;<\/span><\/p>\n<p style=\"line-height: 1.75em;\"><span style=\"font-size: 15px;\">\u8fd1\u65e5\uff0c\u53d1\u8868\u5728\u300aProceedings of the National Academy ofSciences\u300b\u6742\u5fd7\u4e0a\u7684\u4e00\u9879\u5173\u4e8e\u524d\u5217\u817a\u764c\u7684\u6700\u65b0\u7814\u7a76\u53d1\u73b0\uff0c<strong>\u764c\u7ec6\u80de\u4e2d\u67d3\u8272\u4f53\u7684\u975e\u6574\u500d\u6027\u7a0b\u5ea6\u8d8a\u9ad8\uff0c\u60a3\u8005\u7684\u6b7b\u4ea1\u7387\u4e5f\u8d8a\u9ad8\u3002<\/strong>\u7814\u7a76\u7ed3\u679c\u540c\u6837\u663e\u793a\uff0c\u68c0\u6d4b\u764c\u7ec6\u80de\u4e2d\u67d3\u8272\u4f53\u7684\u201c\u975e\u6574\u500d\u6027\u201d\uff0c\u6709\u52a9\u4e8e\u66f4\u51c6\u786e\u5730\u9884\u6d4b\u764c\u75c7\u9884\u540e\uff0c\u5e76\u80fd\u63d0\u793a\u533b\u751f\u54ea\u4e9b\u60a3\u8005\u53ef\u80fd\u9700\u8981\u5f97\u66f4\u79ef\u6781\u7684\u6cbb\u7597\u3002<\/span><\/p>\n<p style=\"line-height: 1.75em;\"><span style=\"font-size: 15px;\"><br  \/><\/span><\/p>\n<p style=\"text-align: center;\"><img class=\"rich_pages\"      style=\"\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2019\/05\/9-1558315798.jpg\" alt=\"PNAS\uff1a\u6700\u65b0\u8bc1\u636e\uff01\u201c\u975e\u6574\u500d\u4f53\u201d\u80bf\u7624\u66f4\u5177\u6740\u4f24\u529b\uff01\" title=\"PNAS\uff1a\u6700\u65b0\u8bc1\u636e\uff01\u201c\u975e\u6574\u500d\u4f53\u201d\u80bf\u7624\u66f4\u5177\u6740\u4f24\u529b\uff01\"  \/><span style=\"color: rgb(136, 136, 136);\"><span style=\"color: rgb(136, 136, 136);font-size: 15px;text-align: justify;\">&nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; <\/span><span style=\"color: rgb(136, 136, 136);font-size: 15px;\">https:\/\/doi.org\/10.1073\/pnas.1902645116<\/span><\/span><\/p>\n<p style=\"line-height: 1.75em;\"><span style=\"font-size: 15px;\"><br  \/><\/span><\/p>\n<p style=\"line-height: 1.75em;\"><span style=\"font-size: 15px;\">\u8be5\u7814\u7a76\u7531\u9ebb\u7701\u7406\u5de5\u5927\u5b66\u751f\u7269\u5b66\u7cfb\u79d1\u8d6b\u7efc\u5408\u764c\u75c7\u7814\u7a76\u6240\u6210\u5458Angelika Amon\u6559\u6388\u548c\u54c8\u4f5b\u5927\u5b66T. H. Chan\u5b66\u9662\u6d41\u884c\u75c5\u5b66\u526f\u6559\u6388Lorelei Mucci\u5171\u540c\u9886\u5bfc\u3002Amon\u8868\u793a\uff1a\u201c\u5bf9\u6211\u800c\u8a00\uff0c\u8fd9\u9879\u7814\u7a76\u662f\u4ee4\u4eba\u5174\u594b\u7684\u3002\u56e0\u4e3a\u524d\u5217\u817a\u764c\u662f\u4e00\u79cd\u666e\u904d\u5b58\u5728\u7684\u764c\u75c7\uff0c\u6211\u4eec\u7684\u7814\u7a76\u6210\u679c\u80fd\u591f\u4e3a\u6cbb\u7597\u63d0\u4f9b\u6709\u7528\u4fe1\u606f\u3002\u201d<\/span><\/p>\n<p style=\"line-height: 1.75em;\"><span style=\"font-size: 15px;\">&nbsp;<\/span><\/p>\n<p style=\"text-align: center;\"><img class=\"rich_pages\"      style=\"text-align: center;white-space: normal;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2019\/05\/0-1558315799.jpeg\" alt=\"PNAS\uff1a\u6700\u65b0\u8bc1\u636e\uff01\u201c\u975e\u6574\u500d\u4f53\u201d\u80bf\u7624\u66f4\u5177\u6740\u4f24\u529b\uff01\" title=\"PNAS\uff1a\u6700\u65b0\u8bc1\u636e\uff01\u201c\u975e\u6574\u500d\u4f53\u201d\u80bf\u7624\u66f4\u5177\u6740\u4f24\u529b\uff01\"  \/><\/p>\n<p style=\"line-height: 1.75em;text-align: center;\"><span style=\"font-size: 15px;color: rgb(136, 136, 136);\">Angelika Amon\u6559\u6388<\/span><\/p>\n<section style=\"max-width: 100%;letter-spacing: 0.544px;white-space: normal;font-size: 15px;width: 0.6em;display: inline-block;vertical-align: middle;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;width: 0.6em;height: 0.6em;display: block;opacity: 0.2;color: rgb(255, 255, 255);background-color: rgb(214, 0, 74);box-sizing: border-box !important;overflow-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"  \/><\/span><span style=\"max-width: 100%;color: rgb(192, 0, 0);box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"margin-top: 2px;margin-bottom: 2px;max-width: 100%;width: 0.6em;height: 0.6em;display: block;opacity: 0.6;color: rgb(255, 255, 255);background-color: rgb(214, 0, 74);box-sizing: border-box !important;overflow-wrap: break-word !important;\"><\/span><span style=\"max-width: 100%;width: 0.6em;height: 0.6em;display: block;opacity: 1;color: rgb(255, 255, 255);background-color: rgb(214, 0, 74);box-sizing: border-box !important;overflow-wrap: break-word !important;\"><\/span><\/span><\/section>\n<section style=\"padding-left: 10px;max-width: 100%;letter-spacing: 0.544px;white-space: normal;font-size: 15px;display: inline-block;vertical-align: middle;font-weight: 700;color: rgb(214, 0, 74);box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<section class=\"\" style=\"max-width: 100%;letter-spacing: 0.544px;background-color: rgb(255, 255, 255);box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;color: rgb(192, 0, 0);letter-spacing: 0.544px;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box;font-family: \u5fae\u8f6f\u96c5\u9ed1, &quot;microsoft yahei&quot;, Arial, sans-serif;font-size: 16px;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 15px;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"font-size: 15px;\"><br  \/><\/span><\/span><\/span><\/strong><\/span><\/section>\n<section class=\"\" style=\"max-width: 100%;letter-spacing: 0.544px;background-color: rgb(255, 255, 255);box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;color: rgb(192, 0, 0);letter-spacing: 0.544px;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box;font-family: \u5fae\u8f6f\u96c5\u9ed1, &quot;microsoft yahei&quot;, Arial, sans-serif;font-size: 16px;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 15px;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"font-size: 15px;\">\u524d\u5217\u817a\u764c\u662f\u7406\u60f3\u6a21\u578b<\/span><\/span><\/span><\/strong><\/span><\/section>\n<p><br  \/><\/p>\n<\/section>\n<p style=\"line-height: 1.75em;\"><span style=\"font-size: 15px;\">\u591a\u5e74\u79d1\u5b66\u63a2\u7a76\u5df2\u8bc1\u5b9e\u764c\u7ec6\u80de\u901a\u5e38\u5177\u6709\u975e\u6574\u500d\u6027\u3002\u90a3\u8fd9\u91cc\u4fbf\u5b58\u5728\u4e00\u4e2a\u6096\u8bba\uff1a<strong>\u4e3a\u4ec0\u4e48\u975e\u6574\u500d\u6027\u4f1a\u635f\u5bb3\u6b63\u5e38\u7ec6\u80de\u7684\u5b58\u6d3b\u80fd\u529b\uff0c\u800c\u975e\u6574\u500d\u6027\u7684\u80bf\u7624\u7ec6\u80de\u5374\u80fd\u591f\u4e0d\u53d7\u63a7\u5236\u5730\u75af\u957f\u5462\uff1f<\/strong><\/span><\/p>\n<p style=\"line-height: 1.75em;\"><span style=\"font-size: 15px;\">&nbsp;<\/span><\/p>\n<p style=\"line-height: 1.75em;\"><span style=\"font-size: 15px;\">\u5c3d\u7ba1\u6709\u6570\u636e\u8868\u660e\uff0c\u975e\u6574\u500d\u6027\u7684\u72b6\u6001\u80fd\u4f7f\u764c\u7ec6\u80de\u66f4\u5177\u653b\u51fb\u6027\uff0c\u4f46\u5728\u5927\u591a\u6570\u7c7b\u578b\u7684\u764c\u75c7\u4e2d\uff0c\u51e0\u4e4e\u6240\u6709\u764c\u7ec6\u80de\u4e2d\u7684\u67d3\u8272\u4f53\u90fd\u5448\u73b0\u975e\u6574\u500d\u4f53\u72b6\u6001\uff0c\u56e0\u6b64\u5f88\u96be\u660e\u786e\u8bc1\u660e\u8fd9\u79cd\u8054\u7cfb\u3002<\/span><\/p>\n<p style=\"line-height: 1.75em;\"><span style=\"font-size: 15px;\">&nbsp;<\/span><\/p>\n<p style=\"line-height: 1.75em;\"><span style=\"font-size: 15px;\">\u5bf9\u6b64\u96be\u9898\uff0cAmon\u6559\u6388\u63d0\u51fa\u4e86\u81ea\u5df1\u7684\u5efa\u8bae\u3002\u5979\u8ba4\u4e3a\uff0c\u524d\u5217\u817a\u764c\u662f\u63a2\u7d22\u975e\u6574\u500d\u6027\u548c\u764c\u75c7\u4fb5\u88ad\u6027\u4e4b\u95f4\u8054\u7cfb\u7684\u7406\u60f3\u6a21\u578b\u3002\u56e0\u4e3a\u4e0e\u5927\u591a\u6570\u5176\u4ed6\u5b9e\u4f53\u80bf\u7624\u4e0d\u540c\uff0c25\uff05\u7684\u524d\u5217\u817a\u764c\u7ec6\u80de\u5e76\u4e0d\u5448\u73b0\u975e\u6574\u500d\u6027\u72b6\u6001\uff0c\u6216\u53ea\u6709\u5c11\u6570\u67d3\u8272\u4f53\u88ab\u6539\u53d8\u3002\u8fd9\u8ba9\u7814\u7a76\u4eba\u5458\u80fd\u591f\u66f4\u8f7b\u677e\u5730\u8bc4\u4f30\u975e\u6574\u500d\u6027\u5bf9\u764c\u75c7\u8fdb\u5c55\u7684\u5f71\u54cd\u3002<\/span><\/p>\n<p style=\"line-height: 1.75em;\"><span style=\"font-size: 15px;\"><br  \/><\/span><\/p>\n<p style=\"text-align: center;\"><img class=\"rich_pages\"      style=\"text-align: center;white-space: normal;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2019\/05\/1-1558315799.jpeg\" alt=\"PNAS\uff1a\u6700\u65b0\u8bc1\u636e\uff01\u201c\u975e\u6574\u500d\u4f53\u201d\u80bf\u7624\u66f4\u5177\u6740\u4f24\u529b\uff01\" title=\"PNAS\uff1a\u6700\u65b0\u8bc1\u636e\uff01\u201c\u975e\u6574\u500d\u4f53\u201d\u80bf\u7624\u66f4\u5177\u6740\u4f24\u529b\uff01\"  \/><\/p>\n<p style=\"line-height: 1.75em;text-align: center;\"><span style=\"font-size: 15px;color: rgb(136, 136, 136);\">\u542b\u6709\u66f4\u9ad8\u7a0b\u5ea6\u975e\u6574\u500d\u6027\u7684\u524d\u5217\u817a\u764c\u7ec6\u80de\u3002\u56fe\u7247\u6765\u6e90\uff1a\u9ebb\u7701\u7406\u5de5\u5b66\u9662<\/span><\/p>\n<p style=\"line-height: 1.75em;\"><span style=\"font-size: 15px;\">&nbsp;<\/span><\/p>\n<p style=\"line-height: 1.75em;\"><span style=\"font-size: 15px;\">\u5728\u8be5\u8bba\u6587\u7684\u7b2c\u4e00\u4f5c\u8005\uff0c\u65af\u9686\u51ef\u7279\u7433\u764c\u75c7\u4e2d\u5fc3\u7684\u7814\u7a76\u52a9\u7406Konrad H. Stopsack\u535a\u58eb\u7684\u5e26\u9886\u4e0b\uff0c\u7814\u7a76\u4eba\u5458\u63d0\u51fa\u4e86\u4e00\u79cd\u8ba1\u7b97\u6bcf\u4e2a\u6837\u672c\u975e\u6574\u500d\u6027\u7a0b\u5ea6\u7684\u65b9\u6cd5\uff0c\u901a\u8fc7\u6bd4\u8f83\u60a3\u8005\u7684\u57fa\u56e0\u5e8f\u5217\u548c\u764c\u75c7\u57fa\u56e0\u7ec4\u56fe\u8c31\u6cdb\u8ba1\u5212\uff08The Cancer Genome Atlas, TCGA\uff09\u6570\u636e\u5e93\u4e2d\u524d\u5217\u817a\u7684\u6570\u636e\uff0c\u4ece\u800c\u9a8c\u8bc1\u975e\u6574\u500d\u6027\u764c\u7ec6\u80de\u66f4\u5177\u653b\u51fb\u6027\u7684\u53ef\u80fd\u3002<\/span><\/p>\n<p style=\"line-height: 1.75em;\"><span style=\"font-size: 15px;\"><br  \/><\/span><\/p>\n<p style=\"line-height: 1.75em;text-align: center;\"><span style=\"font-size: 15px;color: rgb(136, 136, 136);\"><img class=\"rich_pages\"      style=\"text-align: center;white-space: normal;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2019\/05\/8-1558315800.jpeg\" alt=\"PNAS\uff1a\u6700\u65b0\u8bc1\u636e\uff01\u201c\u975e\u6574\u500d\u4f53\u201d\u80bf\u7624\u66f4\u5177\u6740\u4f24\u529b\uff01\" title=\"PNAS\uff1a\u6700\u65b0\u8bc1\u636e\uff01\u201c\u975e\u6574\u500d\u4f53\u201d\u80bf\u7624\u66f4\u5177\u6740\u4f24\u529b\uff01\"  \/><\/span><\/p>\n<p style=\"line-height: 1.75em;text-align: center;\"><span style=\"font-size: 15px;color: rgb(136, 136, 136);\">Konrad H. Stopsack\u535a\u58eb<\/span><\/p>\n<p style=\"line-height: 1.75em;\"><span style=\"font-size: 15px;\"><br  \/><\/span><\/p>\n<p style=\"line-height: 1.75em;\"><span style=\"font-size: 15px;\">\u6700\u540e\uff0c\u7814\u7a76\u4eba\u5458\u5c06\u975e\u6574\u500d\u6027\u4e0e\u60a3\u8005\u7ed3\u679c\u76f8\u5173\u8054\uff0c\u53d1\u73b0<strong>\u975e\u6574\u500d\u6027\u7a0b\u5ea6\u8f83\u9ad8\u7684\u60a3\u8005\u6b7b\u4e8e\u8be5\u75be\u75c5\u7684\u98ce\u9669\u63d0\u9ad8\u4e865\u500d<\/strong>\uff0c\u5373\u4f7f\u5728\u8003\u8651\u4e86Gleason\u8bc4\u5206\uff08\u76ee\u524d\u533b\u7597\u4e2d\u4e00\u79cd\u8861\u91cf\u60a3\u8005\u7ec6\u80de\u5728\u663e\u5fae\u955c\u4e0b\u4e0e\u764c\u7ec6\u80de\u6216\u6b63\u5e38\u7ec6\u80de\u76f8\u4f3c\u7a0b\u5ea6\u7684\u6307\u6807\u7528\u6765\u786e\u5b9a\u75be\u75c5\u7684\u4e25\u91cd\u7a0b\u5ea6\uff09\u7684\u5dee\u5f02\u4e4b\u540e\u4e5f\u662f\u5982\u6b64\u3002<\/span><\/p>\n<p style=\"line-height: 1.75em;\"><span style=\"font-size: 15px;\">&nbsp;<\/span><\/p>\n<p style=\"line-height: 1.75em;\"><span style=\"font-size: 15px;\">Amon\u5728\u4e86\u89e3\u7814\u7a76\u7ed3\u679c\u540e\u8868\u793a\uff0c\u6d4b\u91cf\u764c\u7ec6\u80de\u7684\u975e\u6574\u500d\u6027\u53ef\u4ee5\u5e2e\u52a9\u533b\u751f\u5bf9\u60a3\u8005\u7684\u5371\u9669\u7cfb\u6570\u8fdb\u884c\u5206\u5c42\uff0c\u5e76\u5e2e\u52a9\u4ed6\u4eec\u5bfb\u627e\u66f4\u9002\u5408\u7684\u6cbb\u7597\u65b9\u5f0f\uff0c\u7279\u522b\u662f\u90a3\u4e9b\u98ce\u9669\u8f83\u9ad8\u7684\u764c\u75c7\u4eba\u7fa4\u3002<\/span><\/p>\n<section style=\"max-width: 100%;letter-spacing: 0.544px;white-space: normal;font-size: 15px;width: 0.6em;display: inline-block;vertical-align: middle;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;width: 0.6em;height: 0.6em;display: block;opacity: 0.2;color: rgb(255, 255, 255);background-color: rgb(214, 0, 74);box-sizing: border-box !important;overflow-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"  \/><\/span><span style=\"max-width: 100%;color: rgb(192, 0, 0);box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"margin-top: 2px;margin-bottom: 2px;max-width: 100%;width: 0.6em;height: 0.6em;display: block;opacity: 0.6;color: rgb(255, 255, 255);background-color: rgb(214, 0, 74);box-sizing: border-box !important;overflow-wrap: break-word !important;\"><\/span><span style=\"max-width: 100%;width: 0.6em;height: 0.6em;display: block;opacity: 1;color: rgb(255, 255, 255);background-color: rgb(214, 0, 74);box-sizing: border-box !important;overflow-wrap: break-word !important;\"><\/span><\/span><\/section>\n<section style=\"padding-left: 10px;max-width: 100%;letter-spacing: 0.544px;white-space: normal;font-size: 15px;display: inline-block;vertical-align: middle;font-weight: 700;color: rgb(214, 0, 74);box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<section class=\"\" style=\"max-width: 100%;letter-spacing: 0.544px;background-color: rgb(255, 255, 255);box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;color: rgb(192, 0, 0);letter-spacing: 0.544px;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box;font-family: \u5fae\u8f6f\u96c5\u9ed1, &quot;microsoft yahei&quot;, Arial, sans-serif;font-size: 16px;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 15px;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"font-size: 15px;\"><br  \/><\/span><\/span><\/span><\/strong><\/span><\/section>\n<section class=\"\" style=\"max-width: 100%;letter-spacing: 0.544px;background-color: rgb(255, 255, 255);box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;color: rgb(192, 0, 0);letter-spacing: 0.544px;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box;font-family: \u5fae\u8f6f\u96c5\u9ed1, &quot;microsoft yahei&quot;, Arial, sans-serif;font-size: 16px;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 15px;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"font-size: 15px;\">\u8f6c\u5411\u7532\u72b6\u817a\u764c<\/span><\/span><\/span><\/strong><\/span><\/section>\n<p><br  \/><\/p>\n<\/section>\n<p style=\"line-height: 1.75em;\"><span style=\"font-size: 15px;\">\u7814\u7a76\u4eba\u5458\u8fdb\u4e00\u6b65\u53d1\u73b0\uff0c\u524d\u5217\u817a\u80bf\u7624\u4e2d\u6700\u5e38\u89c1\u7684\u975e\u6574\u500d\u6027\u67d3\u8272\u4f53\u662f7\u53f7\u548c8\u53f7\u67d3\u8272\u4f53\u3002\u76ee\u524d\uff0c\u4ed6\u4eec\u6b63\u8bd5\u56fe\u627e\u51fa\u4f4d\u4e8e\u8fd9\u4e9b\u67d3\u8272\u4f53\u4e0a\u53ef\u80fd\u6709\u52a9\u4e8e\u764c\u7ec6\u80de\u5b58\u6d3b\u548c\u6269\u6563\u7684\u7279\u5b9a\u57fa\u56e0\u3002\u540c\u65f6\uff0c\u4ed6\u4eec\u4e5f\u5728\u7ee7\u7eed\u7814\u7a76\u4e3a\u4ec0\u4e48\u6709\u4e00\u4e9b\u524d\u5217\u817a\u764c\u75c7\u7684\u975e\u6574\u500d\u6027\u4f1a\u66f4\u9ad8\uff1f<\/span><\/p>\n<p style=\"line-height: 1.75em;\"><span style=\"font-size: 15px;\">&nbsp;<\/span><\/p>\n<p style=\"line-height: 1.75em;\"><span style=\"font-size: 15px;\">Mucci\u6559\u6388\u8868\u793a\uff0c\u6211\u4eec\u8ba1\u5212\u5c06\u524d\u5217\u817a\u6d3b\u68c0\u6807\u672c\u8f6c\u5316\u4e3a\u4e34\u5e8a\u5b9e\u9a8c\uff0c\u4ee5\u4e86\u89e3\u524d\u5217\u817a\u80bf\u7624\u4e2d\u53d1\u751f\u9ad8\u7a0b\u5ea6\u975e\u6574\u500d\u6027\u7684\u539f\u56e0\u3002<\/span><\/p>\n<p style=\"line-height: 1.75em;\"><span style=\"font-size: 15px;\">&nbsp;<\/span><\/p>\n<p style=\"line-height: 1.75em;\"><span style=\"font-size: 15px;\">\u540c\u65f6\uff0c\u4e3a\u4e86\u66f4\u597d\u5730\u9a8c\u8bc1\u764c\u7ec6\u80de\u975e\u6574\u500d\u6027\u4e0e\u4fb5\u88ad\u6027\u4e4b\u95f4\u7684\u5173\u7cfb\uff0cAmon\u6559\u6388\u5f00\u59cb\u5173\u6ce8\u7532\u72b6\u817a\u764c\u3002\u4e0e\u524d\u5217\u817a\u764c\u4e00\u6837\uff0c\u5927\u591a\u6570\u7532\u72b6\u817a\u764c\u60a3\u8005\u4e5f\u5177\u6709\u8f83\u4f4e\u7a0b\u5ea6\u7684\u975e\u6574\u500d\u6027\u3002\u7814\u7a76\u5c06\u9a8c\u8bc1\u5177\u6709\u66f4\u9ad8\u7a0b\u5ea6\u7684\u975e\u6574\u500d\u6027\u5728\u7532\u72b6\u817a\u764c\u60a3\u8005\u4e2d\u662f\u5426\u4e5f\u66f4\u9ad8\u7684\u6b7b\u4ea1\u7387\u3002<\/span><\/p>\n<section  class=\"\" style=\"max-width: 100%;letter-spacing: 0.544px;white-space: normal;background-color: rgb(255, 255, 255);caret-color: rgb(51, 51, 51);box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<section  style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<section  class=\"\" style=\"max-width: 100%;line-height: 28.4444px;font-family: \u5fae\u8f6f\u96c5\u9ed1;border-width: 0px;border-style: none;border-color: initial;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<section  style=\"margin: 1em auto;max-width: 100%;border-width: 0px;border-style: none;border-color: initial;text-align: center;width: 941px;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span class=\"\"  style=\"max-width: 100%;width: 941px;border-bottom: 1px solid rgb(172, 29, 16);border-top-color: rgb(172, 29, 16);border-right-color: rgb(172, 29, 16);border-left-color: rgb(172, 29, 16);display: inline-block;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><\/p>\n<section class=\"\" style=\"margin-bottom: -3px;padding-top: 5px;padding-right: 10px;padding-left: 10px;max-width: 100%;display: inline-block;min-height: 32px;border-bottom: 5px solid rgb(172, 29, 16);font-size: 20px;color: rgb(121, 121, 121);box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<p class=\"\" style=\"margin-top: 5px;margin-bottom: 5px;max-width: 100%;min-height: 1em;line-height: 1.6em;font-size: 16px;box-sizing: border-box !important;overflow-wrap: break-word !important;\">End<\/p>\n<\/section>\n<p><\/span><\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<p style=\"max-width: 100%;min-height: 1em;letter-spacing: 0.544px;white-space: normal;background-color: rgb(255, 255, 255);caret-color: rgb(51, 51, 51);box-sizing: border-box !important;overflow-wrap: break-word !important;\"><strong style=\"max-width: 100%;letter-spacing: 0.544px;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 12px;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u53c2\u8003\u8d44\u6599\uff1a<\/span><\/strong><\/p>\n<p style=\"max-width: 100%;min-height: 1em;letter-spacing: 0.544px;white-space: normal;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 12px;box-sizing: border-box !important;overflow-wrap: break-word !important;\">[1]Aneuploidy driveslethal progression in prostate cancer<\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;letter-spacing: 0.544px;white-space: normal;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 12px;box-sizing: border-box !important;overflow-wrap: break-word !important;\">[2]Measuringchromosome imbalance could clarify cancer prognosis<\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;letter-spacing: 0.544px;white-space: normal;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><br  \/><\/p>\n<section  class=\"\" style=\"max-width: 100%;box-sizing: border-box;letter-spacing: 0.544px;white-space: normal;background-color: rgb(255, 255, 255);font-family: \u5fae\u8f6f\u96c5\u9ed1;caret-color: rgb(51, 51, 51);font-size: 16px;color: rgb(62, 62, 62);line-height: 25.6px;border-width: 0px;border-style: none;overflow-wrap: break-word !important;\">\n<section class=\"\"  style=\"padding: 2px;max-width: 100%;box-sizing: border-box;border-width: 1px;border-style: dotted;border-color: rgb(218, 98, 71);overflow-wrap: break-word !important;\">\n<section class=\"\" style=\"margin: 5px auto;max-width: 100%;box-sizing: border-box;border-width: 0px;border-style: none;overflow-wrap: break-word !important;\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;height: 25px;color: inherit;overflow-wrap: break-word !important;\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;height: 25px;width: 50px;float: left;border-top: 2px solid rgb(172, 29, 16);border-right-color: rgb(172, 29, 16);border-bottom-color: rgb(172, 29, 16);border-left: 2px solid rgb(172, 29, 16);color: inherit;overflow-wrap: break-word !important;\"><\/section>\n<\/section>\n<section class=\"\"  style=\"margin: -0.8em 0.3em;padding: 0.8em;max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;color: inherit;\">\n<p class=\"\" style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);font-size: 1em;line-height: 1.75em;word-break: break-all;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span class=\"\" style=\"max-width: 100%;color: rgb(0, 0, 0);line-height: 22.4px;font-size: 14px;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u672c\u6587\u7cfb\u539f\u521b\uff0c\u6b22\u8fce\u4e2a\u4eba\u8f6c\u53d1\u5206\u4eab\u3002\u5176\u4ed6\u4efb\u4f55\u5a92\u4f53\u3001\u7f51\u7ad9\u5982\u9700\u8f6c\u8f7d\uff0c\u987b\u5728\u6b63\u6587\u524d\u6ce8\u660e\u6765\u6e90\u3002<\/span><\/p>\n<\/section>\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;height: 25px;color: inherit;overflow-wrap: break-word !important;\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;height: 25px;width: 50px;float: right;border-bottom: 2px solid rgb(172, 29, 16);border-top-color: rgb(172, 29, 16);border-right: 2px solid rgb(172, 29, 16);border-left-color: rgb(172, 29, 16);color: inherit;overflow-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"  \/><\/section>\n<\/section>\n<\/section>\n<\/section>\n<p><br style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"  \/><\/section>\n<p style=\"max-width: 100%;min-height: 1em;letter-spacing: 0.544px;white-space: normal;background-color: rgb(255, 255, 255);text-align: center;caret-color: rgb(51, 51, 51);box-sizing: border-box !important;overflow-wrap: break-word !important;\"><img class=\"\"      style=\"box-sizing: border-box !important;overflow-wrap: break-word !important;visibility: visible !important;width: 677px !important;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2019\/05\/1-1558315800.jpg\" alt=\"PNAS\uff1a\u6700\u65b0\u8bc1\u636e\uff01\u201c\u975e\u6574\u500d\u4f53\u201d\u80bf\u7624\u66f4\u5177\u6740\u4f24\u529b\uff01\" title=\"PNAS\uff1a\u6700\u65b0\u8bc1\u636e\uff01\u201c\u975e\u6574\u500d\u4f53\u201d\u80bf\u7624\u66f4\u5177\u6740\u4f24\u529b\uff01\"  \/><\/p>\n<\/p><\/div>\n","protected":false},"excerpt":{"rendered":"<p>\u901a\u5e38\u6765\u8bf4\uff0c\u4eba\u7c7b\u7ec6\u80de\u4e2d\u6b63\u5e38\u542b\u670923\u5bf9\u67d3\u8272\u4f53\uff0c\u4efb\u4f55\u67d3\u8272\u4f53\u6570\u76ee\u7684\u504f\u5dee\u5bf9\u4e8e\u7ec6\u80de\u6765\u8bf4\u90fd\u662f\u81f4\u547d\u7684\u4f24\u5bb3\u3002\u4f17\u6240\u5468\u77e5\u7684\u4e00\u4e9b\u9057\u4f20\u6027 [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":112210,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[1],"tags":[],"_links":{"self":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/112209"}],"collection":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/comments?post=112209"}],"version-history":[{"count":1,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/112209\/revisions"}],"predecessor-version":[{"id":112216,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/112209\/revisions\/112216"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/media\/112210"}],"wp:attachment":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/media?parent=112209"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/categories?post=112209"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/tags?post=112209"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}