{"id":11361,"date":"2018-07-21T01:00:00","date_gmt":"2018-07-30T04:04:23","guid":{"rendered":"http:\/\/www.05921.net\/index.php\/2018\/07\/30\/%e3%80%90%e5%b9%b2%e8%b4%a7%e3%80%91%e5%ae%b9%e5%99%a8%e5%af%86%e5%b0%81%e6%80%a7%e6%b5%8b%e8%af%95-ccit\/"},"modified":"2018-07-30T12:04:23","modified_gmt":"2018-07-30T04:04:23","slug":"%e3%80%90%e5%b9%b2%e8%b4%a7%e3%80%91%e5%ae%b9%e5%99%a8%e5%af%86%e5%b0%81%e6%80%a7%e6%b5%8b%e8%af%95-ccit","status":"publish","type":"post","link":"https:\/\/www.05921.net\/index.php\/11361\/","title":{"rendered":"\u3010\u5e72\u8d27\u3011\u5bb9\u5668\u5bc6\u5c01\u6027\u6d4b\u8bd5 &#8211; CCIT"},"content":{"rendered":"<div class=\"bpp-post-content\">\n<p style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;clear: both;min-height: 1em;color: rgb(51, 51, 51);font-family: -apple-system-font, BlinkMacSystemFont, &#39;Helvetica Neue&#39;, &#39;PingFang SC&#39;, &#39;Hiragino Sans GB&#39;, &#39;Microsoft YaHei UI&#39;, &#39;Microsoft YaHei&#39;, Arial, sans-serif;font-size: 17px;font-style: normal;font-variant: normal;font-weight: normal;letter-spacing: 0.544000029563904px;line-height: 27.2000007629395px;orphans: auto;text-align: justify;text-indent: 0px;text-transform: none;white-space: normal;widows: 1;word-spacing: 0px;-webkit-text-stroke-width: 0px;background-color: rgb(255, 255, 255);\"><span style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;color: rgb(0, 112, 192);font-family: \u7b49\u7ebf;font-size: 14px;\">\u5bb9\u5668\u5bc6\u5c01\u6027 (CCIT \u2013Container Closure Integrity Test)\uff0c\u987e\u540d\u601d\u4e49\u5c31\u662f\u68c0\u67e5\u5bb9\u5668\uff08\u5185\u5305\u6750\uff09\u7684\u5bc6\u5c01\u6027\uff08\u5b8c\u6574\u6027\uff0c\u6cc4\u6f0f\u60c5\u51b5\uff09\u3002<\/span><\/p>\n<p style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;clear: both;min-height: 1em;color: rgb(51, 51, 51);font-family: -apple-system-font, BlinkMacSystemFont, &#39;Helvetica Neue&#39;, &#39;PingFang SC&#39;, &#39;Hiragino Sans GB&#39;, &#39;Microsoft YaHei UI&#39;, &#39;Microsoft YaHei&#39;, Arial, sans-serif;font-size: 17px;font-style: normal;font-variant: normal;font-weight: normal;letter-spacing: 0.544000029563904px;line-height: 27.2000007629395px;orphans: auto;text-align: justify;text-indent: 0px;text-transform: none;white-space: normal;widows: 1;word-spacing: 0px;-webkit-text-stroke-width: 0px;background-color: rgb(255, 255, 255);\"><span style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;color: rgb(0, 112, 192);font-family: \u7b49\u7ebf;font-size: 14px;\">&nbsp;<\/span><\/p>\n<p style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;clear: both;min-height: 1em;color: rgb(51, 51, 51);font-family: -apple-system-font, BlinkMacSystemFont, &#39;Helvetica Neue&#39;, &#39;PingFang SC&#39;, &#39;Hiragino Sans GB&#39;, &#39;Microsoft YaHei UI&#39;, &#39;Microsoft YaHei&#39;, Arial, sans-serif;font-size: 17px;font-style: normal;font-variant: normal;font-weight: normal;letter-spacing: 0.544000029563904px;line-height: 27.2000007629395px;orphans: auto;text-indent: 0px;text-transform: none;white-space: normal;widows: 1;word-spacing: 0px;-webkit-text-stroke-width: 0px;text-align: left;background-color: rgb(255, 255, 255);\"><span style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;font-size: 14px;\"><em style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;font-style: italic;\"><span style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;color: rgb(0, 112, 192);font-family: \u7b49\u7ebf;font-size: 14px;\">ISO 8362 states that \u201cThe potency, purity, stability and safety of a medicinal product during its manufacture and storage can strongly be affected by the nature and performance of the primary packaging.\u201d<\/span><\/em><\/span><\/p>\n<p style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;clear: both;min-height: 1em;color: rgb(51, 51, 51);font-family: -apple-system-font, BlinkMacSystemFont, &#39;Helvetica Neue&#39;, &#39;PingFang SC&#39;, &#39;Hiragino Sans GB&#39;, &#39;Microsoft YaHei UI&#39;, &#39;Microsoft YaHei&#39;, Arial, sans-serif;font-size: 17px;font-style: normal;font-variant: normal;font-weight: normal;letter-spacing: 0.544000029563904px;line-height: 27.2000007629395px;orphans: auto;text-indent: 0px;text-transform: none;white-space: normal;widows: 1;word-spacing: 0px;-webkit-text-stroke-width: 0px;text-align: left;background-color: rgb(255, 255, 255);\"><span style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;color: rgb(0, 112, 192);font-family: \u7b49\u7ebf;font-size: 14px;\">&nbsp;<\/span><\/p>\n<p style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;clear: both;min-height: 1em;color: rgb(51, 51, 51);font-family: -apple-system-font, BlinkMacSystemFont, &#39;Helvetica Neue&#39;, &#39;PingFang SC&#39;, &#39;Hiragino Sans GB&#39;, &#39;Microsoft YaHei UI&#39;, &#39;Microsoft YaHei&#39;, Arial, sans-serif;font-size: 17px;font-style: normal;font-variant: normal;font-weight: normal;letter-spacing: 0.544000029563904px;line-height: 27.2000007629395px;orphans: auto;text-indent: 0px;text-transform: none;white-space: normal;widows: 1;word-spacing: 0px;-webkit-text-stroke-width: 0px;text-align: left;background-color: rgb(255, 255, 255);\"><span style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;color: rgb(0, 112, 192);font-family: \u7b49\u7ebf;font-size: 14px;\">\u521d\u7ea7\u5305\u88c5\uff08\u5185\u5305\u6750\u76f8\u5173\uff09\u7684\u81ea\u7136\u5c5e\u6027\u548c\u6027\u80fd\u4f1a\u76f4\u63a5\u5f71\u54cd\u5230\u836f\u54c1\u5728\u5176\u751f\u4ea7\u548c\u50a8\u5b58\u8fc7\u7a0b\u4e2d\u7684\u836f\u6548\uff0c\u7eaf\u5ea6\uff0c\u7a33\u5b9a\u6027\u548c\u5b89\u5168\u6027\u3002<\/span><\/p>\n<p style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;clear: both;min-height: 1em;font-family: -apple-system-font, BlinkMacSystemFont, &#39;Helvetica Neue&#39;, &#39;PingFang SC&#39;, &#39;Hiragino Sans GB&#39;, &#39;Microsoft YaHei UI&#39;, &#39;Microsoft YaHei&#39;, Arial, sans-serif;font-size: 17px;font-style: normal;font-variant: normal;font-weight: normal;letter-spacing: 0.544000029563904px;line-height: 27.2000007629395px;orphans: auto;text-align: justify;text-indent: 0px;text-transform: none;white-space: normal;widows: 1;word-spacing: 0px;-webkit-text-stroke-width: 0px;color: rgb(0, 0, 0);background-color: transparent;\"><br style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/p>\n<p style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;clear: both;min-height: 1em;color: rgb(51, 51, 51);font-family: -apple-system-font, BlinkMacSystemFont, &#39;Helvetica Neue&#39;, &#39;PingFang SC&#39;, &#39;Hiragino Sans GB&#39;, &#39;Microsoft YaHei UI&#39;, &#39;Microsoft YaHei&#39;, Arial, sans-serif;font-size: 17px;font-style: normal;font-variant: normal;font-weight: normal;letter-spacing: 0.544000029563904px;line-height: 27.2000007629395px;orphans: auto;text-indent: 0px;text-transform: none;white-space: normal;widows: 1;word-spacing: 0px;-webkit-text-stroke-width: 0px;text-align: left;background-color: rgb(255, 255, 255);\"><span style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;font-size: 14px;\"><strong style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"><em style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;font-style: italic;\"><span style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;color: black;font-family: \u7b49\u7ebf;text-decoration: underline;\">\u5185\u5305\u6750\u9009\u578b\uff0c\u6e05\u6d01\u548c\u706d\u83cc\uff0c\u90fd\u5c06\u76f4\u63a5\u6216\u95f4\u63a5\u5f71\u54cd\u5230\u5bb9\u5668\u5bc6\u5c01\u6027<\/span><\/em><\/strong><\/span><\/p>\n<p style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;clear: both;min-height: 1em;color: rgb(51, 51, 51);font-family: -apple-system-font, BlinkMacSystemFont, &#39;Helvetica Neue&#39;, &#39;PingFang SC&#39;, &#39;Hiragino Sans GB&#39;, &#39;Microsoft YaHei UI&#39;, &#39;Microsoft YaHei&#39;, Arial, sans-serif;font-size: 17px;font-style: normal;font-variant: normal;font-weight: normal;letter-spacing: 0.544000029563904px;line-height: 27.2000007629395px;orphans: auto;text-indent: 0px;text-transform: none;white-space: normal;widows: 1;word-spacing: 0px;-webkit-text-stroke-width: 0px;text-align: left;background-color: rgb(255, 255, 255);\"><span style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;color: black;font-family: \u7b49\u7ebf;font-size: 14px;\">&nbsp;<\/span><\/p>\n<p style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;clear: both;min-height: 1em;color: rgb(51, 51, 51);font-family: -apple-system-font, BlinkMacSystemFont, &#39;Helvetica Neue&#39;, &#39;PingFang SC&#39;, &#39;Hiragino Sans GB&#39;, &#39;Microsoft YaHei UI&#39;, &#39;Microsoft YaHei&#39;, Arial, sans-serif;font-size: 17px;font-style: normal;font-variant: normal;font-weight: normal;letter-spacing: 0.544000029563904px;line-height: 27.2000007629395px;orphans: auto;text-indent: 0px;text-transform: none;white-space: normal;widows: 1;word-spacing: 0px;-webkit-text-stroke-width: 0px;text-align: left;background-color: rgb(255, 255, 255);\"><span style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;color: black;font-family: \u7b49\u7ebf;font-size: 14px;\">\u5185\u5305\u6750\u7684\u9009\u578b\uff0c\u662f\u4e00\u4e2a\u6bd4\u8f83\u6709\u8da3\u4e5f\u76f8\u5bf9\u590d\u6742\u7684\u8bdd\u9898\u3002\u9664\u4e86\u5173\u7cfb\u5230\u5bb9\u5668\u5bc6\u5c01\u6027\uff0c\u8fd8\u5173\u7cfb\u5230\u5236\u5242\u751f\u4ea7\u8bbe\u5907\u7684\u8bbe\u8ba1\uff0c\u4ea7\u54c1\u7684\u76f8\u5bb9\u6027\uff0c\u4ea7\u54c1\u5de5\u827a\u8f6c\u79fb\u4ee5\u53ca\u7533\u62a5\u7b49\u65b9\u9762\u3002\u6211\u4eec\u5728\u540e\u9762\u7684\u65f6\u95f4\u518d\u4e13\u95e8\u5c31\u8fd9\u4e2a\u8bdd\u9898\u6765\u8fdb\u884c\u8ba8\u8bba\uff0c\u5c31\u4e0d\u5728\u8fd9\u91cc\u7ec6\u8bf4\u4e86\u3002\u800c\u6e05\u6d01\u706d\u83cc\uff0c\u5728\u65e0\u83cc\u5de5\u827a\u76f8\u5173\u7684\u6cd5\u89c4\u548c\u6307\u5357\u4e2d\uff0c\u5bf9\u5185\u5305\u6750\u7684\u5904\u7406\u8981\u6c42\u5e76\u4e0d\u5c11\u89c1\u3002<\/span><\/p>\n<p style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;clear: both;min-height: 1em;color: rgb(51, 51, 51);font-family: -apple-system-font, BlinkMacSystemFont, &#39;Helvetica Neue&#39;, &#39;PingFang SC&#39;, &#39;Hiragino Sans GB&#39;, &#39;Microsoft YaHei UI&#39;, &#39;Microsoft YaHei&#39;, Arial, sans-serif;font-size: 17px;font-style: normal;font-variant: normal;font-weight: normal;letter-spacing: 0.544000029563904px;line-height: 27.2000007629395px;orphans: auto;text-indent: 0px;text-transform: none;white-space: normal;widows: 1;word-spacing: 0px;-webkit-text-stroke-width: 0px;text-align: left;background-color: rgb(255, 255, 255);\"><span style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;color: black;font-family: \u7b49\u7ebf;font-size: 14px;\">&nbsp;<\/span><\/p>\n<p style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;clear: both;min-height: 1em;color: rgb(51, 51, 51);font-family: -apple-system-font, BlinkMacSystemFont, &#39;Helvetica Neue&#39;, &#39;PingFang SC&#39;, &#39;Hiragino Sans GB&#39;, &#39;Microsoft YaHei UI&#39;, &#39;Microsoft YaHei&#39;, Arial, sans-serif;font-size: 17px;font-style: normal;font-variant: normal;font-weight: normal;letter-spacing: 0.544000029563904px;line-height: 27.2000007629395px;orphans: auto;text-indent: 0px;text-transform: none;white-space: normal;widows: 1;word-spacing: 0px;-webkit-text-stroke-width: 0px;text-align: left;background-color: rgb(255, 255, 255);\"><span style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;font-size: 14px;\"><em style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;font-style: italic;\"><span style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;color: black;font-family: \u7b49\u7ebf;font-size: 14px;\">21 CFR 211.94(c) states that \u201cDrug product containers and closures shall be clean and, where indicated by the nature of the drug, sterilized and processed to remove pyrogenic properties to assure that they are suitable for their intended use.\u201d<\/span><\/em><\/span><\/p>\n<p style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;clear: both;min-height: 1em;color: rgb(51, 51, 51);font-family: -apple-system-font, BlinkMacSystemFont, &#39;Helvetica Neue&#39;, &#39;PingFang SC&#39;, &#39;Hiragino Sans GB&#39;, &#39;Microsoft YaHei UI&#39;, &#39;Microsoft YaHei&#39;, Arial, sans-serif;font-size: 17px;font-style: normal;font-variant: normal;font-weight: normal;letter-spacing: 0.544000029563904px;line-height: 27.2000007629395px;orphans: auto;text-indent: 0px;text-transform: none;white-space: normal;widows: 1;word-spacing: 0px;-webkit-text-stroke-width: 0px;text-align: left;background-color: rgb(255, 255, 255);\"><span style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;color: black;font-family: \u7b49\u7ebf;\">&nbsp;<\/span><\/p>\n<p style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;clear: both;min-height: 1em;color: rgb(51, 51, 51);font-family: -apple-system-font, BlinkMacSystemFont, &#39;Helvetica Neue&#39;, &#39;PingFang SC&#39;, &#39;Hiragino Sans GB&#39;, &#39;Microsoft YaHei UI&#39;, &#39;Microsoft YaHei&#39;, Arial, sans-serif;font-size: 17px;font-style: normal;font-variant: normal;font-weight: normal;letter-spacing: 0.544000029563904px;line-height: 27.2000007629395px;orphans: auto;text-indent: 0px;text-transform: none;white-space: normal;widows: 1;word-spacing: 0px;-webkit-text-stroke-width: 0px;text-align: left;background-color: rgb(255, 255, 255);\"><span style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;color: black;font-family: \u7b49\u7ebf;font-size: 14px;\">\u5185\u5305\u6750\u7684\u6e05\u6d01\u706d\u83cc\u5c06\u76f4\u63a5\u6216\u95f4\u63a5\u5f71\u54cd\u5230\u5bb9\u5668\u5bc6\u5c01\u6027\u3002\u897f\u6797\u74f6\u7684\u5904\u7406\u901a\u5e38\u5305\u62ec\u6e05\u6d17\uff0c\u706d\u83cc\u3002\u706d\u83cc\u65b9\u5f0f\u5305\u62ec\u5e72\u70ed\uff08depyrogenation oven\/tunnel\uff09\uff0c\u8f90\u7167\uff08gamma irradiation\uff09\uff0c\u73af\u6c27\u4e59\u70f7\uff08EtO\uff09\u4ee5\u53ca\u84b8\u6c7d\u706d\u83cc\uff08autoclaving\uff09\u3002 \u80f6\u585e\u548c\u94dd\u76d6\u706d\u83cc\u901a\u5e38\u9009\u7528\u84b8\u6c7d\u706d\u83cc\u548c\u8f90\u7167\u706d\u83cc\u65b9\u5f0f\u3002<\/span><\/p>\n<p style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;clear: both;min-height: 1em;color: rgb(51, 51, 51);font-family: -apple-system-font, BlinkMacSystemFont, &#39;Helvetica Neue&#39;, &#39;PingFang SC&#39;, &#39;Hiragino Sans GB&#39;, &#39;Microsoft YaHei UI&#39;, &#39;Microsoft YaHei&#39;, Arial, sans-serif;font-size: 17px;font-style: normal;font-variant: normal;font-weight: normal;letter-spacing: 0.544000029563904px;line-height: 27.2000007629395px;orphans: auto;text-indent: 0px;text-transform: none;white-space: normal;widows: 1;word-spacing: 0px;-webkit-text-stroke-width: 0px;text-align: left;background-color: rgb(255, 255, 255);\"><span style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;font-family: \u7b49\u7ebf;font-size: 14px;\">&nbsp;<\/span><\/p>\n<p style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;clear: both;min-height: 1em;color: rgb(51, 51, 51);font-family: -apple-system-font, BlinkMacSystemFont, &#39;Helvetica Neue&#39;, &#39;PingFang SC&#39;, &#39;Hiragino Sans GB&#39;, &#39;Microsoft YaHei UI&#39;, &#39;Microsoft YaHei&#39;, Arial, sans-serif;font-size: 17px;font-style: normal;font-variant: normal;font-weight: normal;letter-spacing: 0.544000029563904px;line-height: 27.2000007629395px;orphans: auto;text-indent: 0px;text-transform: none;white-space: normal;widows: 1;word-spacing: 0px;-webkit-text-stroke-width: 0px;text-align: left;background-color: rgb(255, 255, 255);\"><span style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;font-size: 14px;\"><strong style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"><em style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;font-style: italic;\"><span style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;color: rgb(0, 112, 192);font-family: \u7b49\u7ebf;font-size: 14px;text-decoration: underline;\">\u5bb9\u5668\u5bc6\u5c01\u6027\u6d4b\u8bd5\u65b9\u6cd5\u6d4b\u8bd5\u9636\u6bb5<\/span><\/em><\/strong><\/span><\/p>\n<p style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;clear: both;min-height: 1em;color: rgb(51, 51, 51);font-family: -apple-system-font, BlinkMacSystemFont, &#39;Helvetica Neue&#39;, &#39;PingFang SC&#39;, &#39;Hiragino Sans GB&#39;, &#39;Microsoft YaHei UI&#39;, &#39;Microsoft YaHei&#39;, Arial, sans-serif;font-size: 17px;font-style: normal;font-variant: normal;font-weight: normal;letter-spacing: 0.544000029563904px;line-height: 27.2000007629395px;orphans: auto;text-indent: 0px;text-transform: none;white-space: normal;widows: 1;word-spacing: 0px;-webkit-text-stroke-width: 0px;text-align: left;background-color: rgb(255, 255, 255);\"><span style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;color: rgb(0, 112, 192);font-family: \u7b49\u7ebf;\">&nbsp;<\/span><\/p>\n<p style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;clear: both;min-height: 1em;color: rgb(51, 51, 51);font-family: -apple-system-font, BlinkMacSystemFont, &#39;Helvetica Neue&#39;, &#39;PingFang SC&#39;, &#39;Hiragino Sans GB&#39;, &#39;Microsoft YaHei UI&#39;, &#39;Microsoft YaHei&#39;, Arial, sans-serif;font-size: 17px;font-style: normal;font-variant: normal;font-weight: normal;letter-spacing: 0.544000029563904px;line-height: 27.2000007629395px;orphans: auto;text-indent: 0px;text-transform: none;white-space: normal;widows: 1;word-spacing: 0px;-webkit-text-stroke-width: 0px;text-align: left;background-color: rgb(255, 255, 255);\"><span style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;color: rgb(0, 112, 192);font-family: \u7b49\u7ebf;font-size: 14px;\">\u5bb9\u5668\u5bc6\u5c01\u6027\u6d4b\u8bd5\u5206\u4e3a\u7269\u7406\u7684\uff08<\/span><span style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;color: rgb(255, 79, 121);font-family: \u7b49\u7ebf;font-size: 14px;\">Physical CCIT<\/span><span style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;color: rgb(0, 112, 192);font-family: \u7b49\u7ebf;font-size: 14px;\">\uff09\u548c\u5fae\u751f\u7269\u6d4b\u8bd5\uff08<\/span><span style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;color: rgb(255, 79, 121);font-family: \u7b49\u7ebf;font-size: 14px;\">Microbial CCIT<\/span><span style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;color: rgb(0, 112, 192);font-family: \u7b49\u7ebf;font-size: 14px;\">\uff09\u3002\u6d4b\u8bd5\u65b9\u6cd5\u5305\u62ec\u5e38\u89c1\u7684\u4e9a\u7532\u57fa\u84dd\u67d3\u8272\uff0c\u771f\u7a7a\u8870\u51cf\uff0c\u6fc0\u5149\uff0c\u5fae\u751f\u7269\u4fb5\u5165\u6cd5\u7b49\u7b49\u3002\u65b9\u6cd5\u9009\u62e9\u65f6\uff0c\u9700\u8003\u8651\u5404\u79cd\u56e0\u7d20\uff0c\u5982\u5305\u88c5\u672c\u8eab\u3001\u5305\u88c5\u5185\u5bb9\u7269\u3001\u5bc6\u5c01\u7ec4\u4ef6\u7684\u5339\u914d\u3001\u65b9\u6cd5\u672c\u8eab\u7684\u7279\u70b9\u3001\u68c0\u51fa\u9650\u7b49\u3002<\/span><\/p>\n<p style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;clear: both;min-height: 1em;color: rgb(51, 51, 51);font-family: -apple-system-font, BlinkMacSystemFont, &#39;Helvetica Neue&#39;, &#39;PingFang SC&#39;, &#39;Hiragino Sans GB&#39;, &#39;Microsoft YaHei UI&#39;, &#39;Microsoft YaHei&#39;, Arial, sans-serif;font-size: 17px;font-style: normal;font-variant: normal;font-weight: normal;letter-spacing: 0.544000029563904px;line-height: 27.2000007629395px;orphans: auto;text-indent: 0px;text-transform: none;white-space: normal;widows: 1;word-spacing: 0px;-webkit-text-stroke-width: 0px;text-align: left;background-color: rgb(255, 255, 255);\"><span style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;color: rgb(0, 112, 192);font-family: \u7b49\u7ebf;font-size: 14px;\">&nbsp;<\/span><\/p>\n<p style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;clear: both;min-height: 1em;color: rgb(51, 51, 51);font-family: -apple-system-font, BlinkMacSystemFont, &#39;Helvetica Neue&#39;, &#39;PingFang SC&#39;, &#39;Hiragino Sans GB&#39;, &#39;Microsoft YaHei UI&#39;, &#39;Microsoft YaHei&#39;, Arial, sans-serif;font-size: 17px;font-style: normal;font-variant: normal;font-weight: normal;letter-spacing: 0.544000029563904px;line-height: 27.2000007629395px;orphans: auto;text-align: justify;text-indent: 0px;text-transform: none;white-space: normal;widows: 1;word-spacing: 0px;-webkit-text-stroke-width: 0px;background-color: rgb(255, 255, 255);\"><span style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;color: rgb(0, 112, 192);font-family: \u7b49\u7ebf;font-size: 14px;\"><span style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;color: rgb(0, 112, 192);font-family: Wingdings;font-size: 14px;font-style: normal;font-variant: normal;font-weight: 400;letter-spacing: normal;orphans: 2;text-align: left;text-decoration: none;text-indent: -28px;text-transform: none;-webkit-text-stroke-width: 0px;word-spacing: 0px;background-color: transparent;\" lang=\"EN-US\">\u00d8<span style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\">&nbsp;<\/span><\/span><span style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;color: rgb(0, 112, 192);font-family: \u7b49\u7ebf;font-size: 14px;font-style: normal;font-variant: normal;font-weight: 400;letter-spacing: normal;orphans: 2;text-align: left;text-decoration: none;text-indent: -28px;text-transform: none;-webkit-text-stroke-width: 0px;word-spacing: 0px;background-color: transparent;\"><\/span>\u5c31\u7269\u7406\u6d4b\u8bd5\u800c\u8a00\uff0c\u6700\u4e3a\u5e38\u89c1\u7684\u6709\u4e9a\u7532\u57fa\u84dd\u67d3\u8272\u3002\u4ee5\u53ca\u771f\u7a7a\u8870\u51cf\u6cd5\u548c\u6fc0\u5149\u6d4b\u8bd5\u3002\u771f\u7a7a\u8870\u51cf\u76f8\u5bf9\u6765\u8bf4\u9002\u7528\u6027\u8f83\u5e7f\uff0c\u5bf9\u4ea7\u54c1\u65e0\u635f\uff0c\u53ef\u4ee5\u6d4b\u6c14\u6f0f\u548c\u6db2\u6f0f\uff0c\u53ef\u4ee5\u6d4b\u8bd5\u5404\u79cd\u9876\u7a7a\u6761\u4ef6\u7684\u5305\u88c5\uff0c\u5e94\u7528\u6700\u6210\u719f\u3002\u800c\u6fc0\u5149\u6cd5\u591a\u9002\u7528\u4e8e\u9ad8\u771f\u7a7a\u51bb\u5e72\u897f\u6797\u74f6\uff0c\u5145\u6c2e\u6c34\u9488\u897f\u6797\u74f6\u7b49\u3002<\/span><\/p>\n<p style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;clear: both;min-height: 1em;color: rgb(51, 51, 51);font-family: -apple-system-font, BlinkMacSystemFont, &#39;Helvetica Neue&#39;, &#39;PingFang SC&#39;, &#39;Hiragino Sans GB&#39;, &#39;Microsoft YaHei UI&#39;, &#39;Microsoft YaHei&#39;, Arial, sans-serif;font-size: 17px;font-style: normal;font-variant: normal;font-weight: normal;letter-spacing: 0.544000029563904px;line-height: 27.2000007629395px;orphans: auto;text-align: justify;text-indent: 0px;text-transform: none;white-space: normal;widows: 1;word-spacing: 0px;-webkit-text-stroke-width: 0px;background-color: rgb(255, 255, 255);\"><br style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/p>\n<p style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;clear: both;min-height: 1em;color: rgb(51, 51, 51);font-family: -apple-system-font, BlinkMacSystemFont, &#39;Helvetica Neue&#39;, &#39;PingFang SC&#39;, &#39;Hiragino Sans GB&#39;, &#39;Microsoft YaHei UI&#39;, &#39;Microsoft YaHei&#39;, Arial, sans-serif;font-size: 17px;font-style: normal;font-variant: normal;font-weight: normal;letter-spacing: 0.544000029563904px;line-height: 27.2000007629395px;orphans: auto;text-indent: 0px;text-transform: none;white-space: normal;widows: 1;word-spacing: 0px;-webkit-text-stroke-width: 0px;text-align: left;background-color: rgb(255, 255, 255);\"><span style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;color: rgb(0, 112, 192);font-family: \u7b49\u7ebf;font-size: 14px;\">\u5177\u4f53\u6d4b\u8bd5\u539f\u7406\u4e3e2\u4e2a\u4f8b\u5b50\uff1a<\/span><\/p>\n<ul class=\"list-paddingleft-2\" style=\"list-style-type: disc;margin-left: 0px;margin-right: 0px;\">\n<li>\n<p style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;clear: both;min-height: 1em;\"><span style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;color: rgb(0, 112, 192);font-family: \u7b49\u7ebf;font-size: 14px;\">\u771f\u7a7a\u8870\u51cf\uff0cCycle 1 \u80fd\u6709\u6548\u68c0\u6d4b\u51fa\u5927\u7684\u6cc4\u6f0f\uff0c\u800cCycle 2 \u53ef\u4ee5\u68c0\u6d4b\u51fa\u5fae\u6f0f\u3002<\/span><\/p>\n<p style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;clear: both;min-height: 1em;\"><img      class=\"\"  style=\"margin: 0px;padding: 0px;height: auto !important;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;width: 405px !important;visibility: visible !important;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/07\/beepress3-1532923463.jpg\" alt=\"\u3010\u5e72\u8d27\u3011\u5bb9\u5668\u5bc6\u5c01\u6027\u6d4b\u8bd5 - CCIT\" title=\"\u3010\u5e72\u8d27\u3011\u5bb9\u5668\u5bc6\u5c01\u6027\u6d4b\u8bd5 - CCIT\"  \/><\/p>\n<\/li>\n<\/ul>\n<p style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;clear: both;min-height: 1em;color: rgb(51, 51, 51);font-family: -apple-system-font, BlinkMacSystemFont, &#39;Helvetica Neue&#39;, &#39;PingFang SC&#39;, &#39;Hiragino Sans GB&#39;, &#39;Microsoft YaHei UI&#39;, &#39;Microsoft YaHei&#39;, Arial, sans-serif;font-size: 17px;font-style: normal;font-variant: normal;font-weight: normal;letter-spacing: 0.544000029563904px;line-height: 27.2000007629395px;orphans: auto;text-align: justify;text-indent: 0px;text-transform: none;white-space: normal;widows: 1;word-spacing: 0px;-webkit-text-stroke-width: 0px;background-color: rgb(255, 255, 255);\"><br style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/p>\n<p style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;clear: both;min-height: 1em;color: rgb(51, 51, 51);font-family: -apple-system-font, BlinkMacSystemFont, &#39;Helvetica Neue&#39;, &#39;PingFang SC&#39;, &#39;Hiragino Sans GB&#39;, &#39;Microsoft YaHei UI&#39;, &#39;Microsoft YaHei&#39;, Arial, sans-serif;font-size: 17px;font-style: normal;font-variant: normal;font-weight: normal;letter-spacing: 0.544000029563904px;line-height: 27.2000007629395px;orphans: auto;text-align: justify;text-indent: 0px;text-transform: none;white-space: normal;widows: 1;word-spacing: 0px;-webkit-text-stroke-width: 0px;background-color: rgb(255, 255, 255);\"><span style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;color: rgb(0, 112, 192);font-family: \u7b49\u7ebf;font-size: 16px;\"><br style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/span><\/p>\n<ul class=\"list-paddingleft-2\" style=\"list-style-type: disc;margin-left: 0px;margin-right: 0px;\">\n<li>\n<p style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;clear: both;min-height: 1em;\"><span style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;color: rgb(0, 112, 192);font-family: \u7b49\u7ebf;font-size: 14px;\">\u6fc0\u5149\u68c0\u6f0f\uff0c\u56e0\u6cc4\u6f0f\uff0c\u7a7a\u6c14\u4e2d\u7684\u6c27\uff0c\u6c34\u4efd\u548cCO2\u4fb5\u5165\u5305\u88c5\u5bb9\u5668\u4e2d\uff0c\u4f7f\u9876\u7a7a\u6761\u4ef6\u53d1\u751f\u6539\u53d8\u3002\u901a\u8fc7\u6fc0\u5149\u6cd5\u76d1\u6d4b\u9876\u7a7a\u53d8\u5316\uff0c\u53ef\u6d4b\u8bd5\u5305\u88c5\u5bb9\u5668\u662f\u5426\u6cc4\u6f0f\u53ca\u6cc4\u6f0f\u7a0b\u5ea6\u3002<\/span><\/p>\n<p style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;clear: both;min-height: 1em;\">\n<\/li>\n<\/ul>\n<p style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;clear: both;min-height: 1em;color: rgb(51, 51, 51);font-family: -apple-system-font, BlinkMacSystemFont, &#39;Helvetica Neue&#39;, &#39;PingFang SC&#39;, &#39;Hiragino Sans GB&#39;, &#39;Microsoft YaHei UI&#39;, &#39;Microsoft YaHei&#39;, Arial, sans-serif;font-size: 17px;font-style: normal;font-variant: normal;font-weight: normal;letter-spacing: 0.544000029563904px;line-height: 27.2000007629395px;orphans: auto;text-align: justify;text-indent: 0px;text-transform: none;white-space: normal;widows: 1;word-spacing: 0px;-webkit-text-stroke-width: 0px;background-color: rgb(255, 255, 255);\"><br style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/p>\n<p style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;clear: both;min-height: 1em;color: rgb(51, 51, 51);font-family: -apple-system-font, BlinkMacSystemFont, &#39;Helvetica Neue&#39;, &#39;PingFang SC&#39;, &#39;Hiragino Sans GB&#39;, &#39;Microsoft YaHei UI&#39;, &#39;Microsoft YaHei&#39;, Arial, sans-serif;font-size: 17px;font-style: normal;font-variant: normal;font-weight: normal;letter-spacing: 0.544000029563904px;line-height: 27.2000007629395px;orphans: auto;text-align: justify;text-indent: 0px;text-transform: none;white-space: normal;widows: 1;word-spacing: 0px;-webkit-text-stroke-width: 0px;background-color: rgb(255, 255, 255);\"><span style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;color: rgb(0, 112, 192);font-family: \u7b49\u7ebf;font-size: 16px;\"><\/span><\/p>\n<p style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;clear: both;min-height: 1em;color: rgb(51, 51, 51);font-family: -apple-system-font, BlinkMacSystemFont, &#39;Helvetica Neue&#39;, &#39;PingFang SC&#39;, &#39;Hiragino Sans GB&#39;, &#39;Microsoft YaHei UI&#39;, &#39;Microsoft YaHei&#39;, Arial, sans-serif;font-size: 17px;font-style: normal;font-variant: normal;font-weight: normal;letter-spacing: 0.544000029563904px;line-height: 27.2000007629395px;orphans: auto;text-align: justify;text-indent: 0px;text-transform: none;white-space: normal;widows: 1;word-spacing: 0px;-webkit-text-stroke-width: 0px;background-color: rgb(255, 255, 255);\"><span style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;color: rgb(255, 79, 121);font-family: \u7b49\u7ebf;font-size: 14px;\">Physical CCIT<\/span><span style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;color: rgb(0, 112, 192);font-family: \u7b49\u7ebf;font-size: 14px;\"><span class=\"Apple-converted-space\">&nbsp;<\/span>\u901a\u5e38\u5728\u4ee5\u4e0b\u51e0\u4e2a\u9636\u6bb5\u8fdb\u884c\uff1a<\/span><\/p>\n<p style=\"margin: 0px 0px 0px 24px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;clear: both;min-height: 1em;color: rgb(51, 51, 51);font-family: -apple-system-font, BlinkMacSystemFont, &#39;Helvetica Neue&#39;, &#39;PingFang SC&#39;, &#39;Hiragino Sans GB&#39;, &#39;Microsoft YaHei UI&#39;, &#39;Microsoft YaHei&#39;, Arial, sans-serif;font-size: 17px;font-style: normal;font-variant: normal;font-weight: normal;letter-spacing: 0.544000029563904px;line-height: 27.2000007629395px;orphans: auto;text-transform: none;white-space: normal;widows: 1;word-spacing: 0px;-webkit-text-stroke-width: 0px;text-align: left;text-indent: -18pt;background-color: rgb(255, 255, 255);\"><span style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;color: rgb(0, 112, 192);font-size: 14px;\"><span style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;font-family: \u7b49\u7ebf;font-size: 14px;\">1.<\/span><span style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"><span class=\"Apple-converted-space\">&nbsp;<\/span>&nbsp;<\/span><\/span><span style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"><span class=\"Apple-converted-space\">&nbsp;<\/span><\/span><span style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;font-size: 14px;\"><span style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;color: rgb(0, 112, 192);font-family: \u7b49\u7ebf;font-size: 14px;\" lang=\"EN-US\">\u8bbe\u5907\u9a8c\u6536\u9636\u6bb5<span class=\"Apple-converted-space\">&nbsp;<\/span><\/span><span style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;color: rgb(0, 112, 192);font-family: Wingdings;font-size: 14px;\" lang=\"EN-US\">\u00e0<\/span><span style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;color: rgb(0, 112, 192);font-family: \u7b49\u7ebf;font-size: 14px;\"><span class=\"Apple-converted-space\">&nbsp;<\/span>\u5bb9\u5668\u5bc6\u5c01\u6027\u901a\u5e38\u987b\u8981\u4f5c\u4e3a\u5236\u5242\u751f\u4ea7\u8bbe\u5907<span style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;font-size: 14px;\" lang=\"EN-US\">OQ<span class=\"Apple-converted-space\">&nbsp;<\/span><\/span>\u548c<span style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;font-size: 14px;\" lang=\"EN-US\">PQ<span class=\"Apple-converted-space\">&nbsp;<\/span><\/span>\u7684\u6d4b\u8bd5\u9879\u76ee\uff0c\u786e\u8ba4\u5bc6\u5c01\u53c2\u6570\uff0c\u6d4b\u8bd5\u5bb9\u5668\u5bc6\u5c01\u6027\uff0c\u6d4b\u8bd5\u5408\u683c\u540e\uff0c\u76f8\u5173\u53c2\u6570\u624d\u53ef\u7b97\u6700\u7ec8\u786e\u8ba4\u4e0b\u6765\u3002<\/span><\/span><span style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;color: rgb(0, 112, 192);font-family: \u7b49\u7ebf;\"><\/span><\/p>\n<p style=\"margin: 0px 0px 0px 24px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;clear: both;min-height: 1em;color: rgb(51, 51, 51);font-family: -apple-system-font, BlinkMacSystemFont, &#39;Helvetica Neue&#39;, &#39;PingFang SC&#39;, &#39;Hiragino Sans GB&#39;, &#39;Microsoft YaHei UI&#39;, &#39;Microsoft YaHei&#39;, Arial, sans-serif;font-size: 17px;font-style: normal;font-variant: normal;font-weight: normal;letter-spacing: 0.544000029563904px;line-height: 27.2000007629395px;orphans: auto;text-transform: none;white-space: normal;widows: 1;word-spacing: 0px;-webkit-text-stroke-width: 0px;text-align: left;text-indent: -18pt;background-color: rgb(255, 255, 255);\"><span style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;color: rgb(0, 112, 192);font-size: 14px;\"><span style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;font-family: \u7b49\u7ebf;\">2.<\/span><span style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;line-height: normal;\"><span class=\"Apple-converted-space\">&nbsp;<\/span>&nbsp;<span class=\"Apple-converted-space\">&nbsp;<\/span><\/span><\/span><span style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;font-family: \u7b49\u7ebf;\">\u5982\u679c\u5728\u521d\u59cb\u9a8c\u8bc1\u540e\uff0c\u5f15\u5165\u65b0\u7684\u5185\u5305\u6750\uff0c\u5219\u5e94\u8be5\u5728\u5de5\u7a0b\u6279\u6216\u751a\u81f3\u66f4\u65e9\u9636\u6bb5\u8fdb\u884c\u5bc6\u5c01\u53c2\u6570\u7684\u5f00\u53d1\u548c\u5bc6\u5c01\u6027\u9a8c\u8bc1\u3002<\/span><span style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\" lang=\"EN-US\"><\/span><\/span><\/p>\n<p style=\"margin: 0px 0px 0px 24px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;clear: both;min-height: 1em;color: rgb(51, 51, 51);font-family: -apple-system-font, BlinkMacSystemFont, &#39;Helvetica Neue&#39;, &#39;PingFang SC&#39;, &#39;Hiragino Sans GB&#39;, &#39;Microsoft YaHei UI&#39;, &#39;Microsoft YaHei&#39;, Arial, sans-serif;font-size: 17px;font-style: normal;font-variant: normal;font-weight: normal;letter-spacing: 0.544000029563904px;line-height: 27.2000007629395px;orphans: auto;text-transform: none;white-space: normal;widows: 1;word-spacing: 0px;-webkit-text-stroke-width: 0px;text-align: left;text-indent: -18pt;background-color: rgb(255, 255, 255);\"><span style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;color: rgb(0, 112, 192);font-size: 14px;\"><span style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;font-size: 14px;\"><span style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;font-family: \u7b49\u7ebf;font-size: 14px;\">3.<\/span><span style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"><span class=\"Apple-converted-space\">&nbsp;<\/span>&nbsp;<span class=\"Apple-converted-space\">&nbsp;<\/span><\/span><\/span><span style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;font-family: \u7b49\u7ebf;font-size: 14px;\">\u6bcf\u5e74\u7684\u8bbe\u5907\u6027\u80fd\u518d\u9a8c\u8bc1\uff0c\u9700\u8981\u53d6\u6837\u8fdb\u884c\u5bb9\u5668\u5bc6\u5c01\u6027\u6d4b\u8bd5\uff0c\u5df2\u786e\u4fdd\u8bbe\u5907\u957f\u671f\u4f7f\u7528\uff0c\u78e8\u635f\u8001\u5316\u7b49\u4e0d\u4f1a\u6700\u7ec8\u5f71\u54cd\u5230\u5bb9\u5668\u5bc6\u5c01\u6027\u95ee\u9898\u3002<\/span><span style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;font-size: 14px;\" lang=\"EN-US\"><\/span><\/span><\/p>\n<p style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;clear: both;min-height: 1em;color: rgb(51, 51, 51);font-family: -apple-system-font, BlinkMacSystemFont, &#39;Helvetica Neue&#39;, &#39;PingFang SC&#39;, &#39;Hiragino Sans GB&#39;, &#39;Microsoft YaHei UI&#39;, &#39;Microsoft YaHei&#39;, Arial, sans-serif;font-size: 17px;font-style: normal;font-variant: normal;font-weight: normal;letter-spacing: 0.544000029563904px;line-height: 27.2000007629395px;orphans: auto;text-align: justify;text-indent: 0px;text-transform: none;white-space: normal;widows: 1;word-spacing: 0px;-webkit-text-stroke-width: 0px;background-color: rgb(255, 255, 255);\"><br style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/p>\n<p style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;clear: both;min-height: 1em;color: rgb(51, 51, 51);font-family: -apple-system-font, BlinkMacSystemFont, &#39;Helvetica Neue&#39;, &#39;PingFang SC&#39;, &#39;Hiragino Sans GB&#39;, &#39;Microsoft YaHei UI&#39;, &#39;Microsoft YaHei&#39;, Arial, sans-serif;font-size: 17px;font-style: normal;font-variant: normal;font-weight: normal;letter-spacing: 0.544000029563904px;line-height: 27.2000007629395px;orphans: auto;text-align: justify;text-indent: 0px;text-transform: none;white-space: normal;widows: 1;word-spacing: 0px;-webkit-text-stroke-width: 0px;background-color: rgb(255, 255, 255);\"><span style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;color: rgb(0, 112, 192);font-family: \u7b49\u7ebf;font-size: 14px;\">\u901a\u5e38\u8be5\u5bc6\u5c01\u662f\u6d4b\u52a0\u585e\u8f67\u76d6\u540e\u3002\u4f46\u4e2d\u56fdGMP\u6709\u8981\u6c42\u8bc1\u660e\u52a0\u585e\u540e\uff08\u8f67\u76d6\u524d\uff09\u7684\u5bb9\u5668\u5bc6\u5c01\u7684\u4e00\u4e2a\u72b6\u6001\u3002\u800c\u6709\u4e9b\u6b27\u7f8e\u4f01\u4e1a\u5185\u63a7\u6807\u51c6\u4e5f\u5305\u62ec\u4e86\u52a0\u585e\u540e\u8f67\u76d6\u524d\u7684\u5bb9\u5668\u5bc6\u5c01\u6027\uff0c\u53ea\u662f\uff0c\u8fd9\u4e0d\u662f\u56e0\u4e3a\u6b27\u7f8e\u6cd5\u89c4\u6216\u6307\u5357\u8981\u6c42\uff0c\u800c\u662f\u7531\u4e8e\u516c\u53f8\u7684\u5de5\u827a\u6d41\u7a0b\uff0c\u52a0\u585e\u540e\u534a\u6210\u54c1\u4f1a\u572810 000\u7ea7\u751a\u81f3100 000\u7ea7\u6682\u65f6\u6027\/\u77ed\u65f6\u95f4\u50a8\u5b58\uff0c\u6216\u8005\u8bb2\u8fc7\u6e21\u3002\u6240\u4ee5\u57fa\u4e8e\u4f01\u4e1a\u5185\u90e8\u98ce\u9669\u63a7\u5236\u7684\u89d2\u5ea6\uff0c\u52a0\u585e\u540e\u8f67\u76d6\u524d\u505a\u5bc6\u5c01\u6027\u4e5f\u662f\u6709\u7684\uff0c\u6b64\u65f6\u901a\u5e38\u9009\u7528\u6fc0\u5149\u6cd5\u8fdb\u884c\u68c0\u6d4b\u3002\u5f53\u7136\uff0c\u8f67\u76d6\u4e4b\u540e\u7684\u5bc6\u5c01\u6027\u662f\u65e0\u8bba\u5982\u4f55\u4e0d\u53ef\u5c11\u7684\u3002<\/span><\/p>\n<p style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;clear: both;min-height: 1em;color: rgb(51, 51, 51);font-family: -apple-system-font, BlinkMacSystemFont, &#39;Helvetica Neue&#39;, &#39;PingFang SC&#39;, &#39;Hiragino Sans GB&#39;, &#39;Microsoft YaHei UI&#39;, &#39;Microsoft YaHei&#39;, Arial, sans-serif;font-size: 17px;font-style: normal;font-variant: normal;font-weight: normal;letter-spacing: 0.544000029563904px;line-height: 27.2000007629395px;orphans: auto;text-align: justify;text-indent: 0px;text-transform: none;white-space: normal;widows: 1;word-spacing: 0px;-webkit-text-stroke-width: 0px;background-color: rgb(255, 255, 255);\"><br style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/p>\n<p style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;clear: both;min-height: 1em;color: rgb(51, 51, 51);font-family: -apple-system-font, BlinkMacSystemFont, &#39;Helvetica Neue&#39;, &#39;PingFang SC&#39;, &#39;Hiragino Sans GB&#39;, &#39;Microsoft YaHei UI&#39;, &#39;Microsoft YaHei&#39;, Arial, sans-serif;font-size: 17px;font-style: normal;font-variant: normal;font-weight: normal;letter-spacing: 0.544000029563904px;line-height: 27.2000007629395px;orphans: auto;text-align: justify;text-indent: 0px;text-transform: none;white-space: normal;widows: 1;word-spacing: 0px;-webkit-text-stroke-width: 0px;background-color: rgb(255, 255, 255);\"><span style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;color: rgb(0, 112, 192);font-family: \u7b49\u7ebf;font-size: 14px;\">&nbsp;<\/span><\/p>\n<p style=\"margin: 0px 0px 0px 28px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;clear: both;min-height: 1em;color: rgb(51, 51, 51);font-family: -apple-system-font, BlinkMacSystemFont, &#39;Helvetica Neue&#39;, &#39;PingFang SC&#39;, &#39;Hiragino Sans GB&#39;, &#39;Microsoft YaHei UI&#39;, &#39;Microsoft YaHei&#39;, Arial, sans-serif;font-size: 17px;font-style: normal;font-variant: normal;font-weight: normal;letter-spacing: 0.544000029563904px;line-height: 27.2000007629395px;orphans: auto;text-transform: none;white-space: normal;widows: 1;word-spacing: 0px;-webkit-text-stroke-width: 0px;text-align: left;text-indent: -21pt;background-color: rgb(255, 255, 255);\"><span style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;font-size: 14px;\"><span style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;color: rgb(0, 112, 192);font-family: Wingdings;font-size: 14px;\" lang=\"EN-US\">\u00d8<span style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\">&nbsp;<\/span><\/span><span style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;color: rgb(0, 112, 192);font-family: \u7b49\u7ebf;font-size: 14px;\">\u5fae\u751f\u7269\u6d4b\u8bd5\u5219\u6307\u7684\u662f\u5fae\u751f\u7269\u4fb5\u5165\u3002<\/span><\/span><\/p>\n<p style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;clear: both;min-height: 1em;color: rgb(51, 51, 51);font-family: -apple-system-font, BlinkMacSystemFont, &#39;Helvetica Neue&#39;, &#39;PingFang SC&#39;, &#39;Hiragino Sans GB&#39;, &#39;Microsoft YaHei UI&#39;, &#39;Microsoft YaHei&#39;, Arial, sans-serif;font-size: 17px;font-style: normal;font-variant: normal;font-weight: normal;letter-spacing: 0.544000029563904px;line-height: 27.2000007629395px;orphans: auto;text-indent: 0px;text-transform: none;white-space: normal;widows: 1;word-spacing: 0px;-webkit-text-stroke-width: 0px;text-align: left;background-color: rgb(255, 255, 255);\"><span style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;color: rgb(255, 79, 121);font-family: \u7b49\u7ebf;font-size: 14px;\">Microbial CCIT<\/span><span style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;color: rgb(0, 112, 192);font-family: \u7b49\u7ebf;font-size: 14px;\"><span class=\"Apple-converted-space\">&nbsp;<\/span>\u901a\u5e38\u5728\u4ee5\u4e0b\u51e0\u4e2a\u9636\u6bb5\u8fdb\u884c\uff1a<\/span><\/p>\n<p style=\"margin: 0px 0px 0px 24px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;clear: both;min-height: 1em;color: rgb(51, 51, 51);font-family: -apple-system-font, BlinkMacSystemFont, &#39;Helvetica Neue&#39;, &#39;PingFang SC&#39;, &#39;Hiragino Sans GB&#39;, &#39;Microsoft YaHei UI&#39;, &#39;Microsoft YaHei&#39;, Arial, sans-serif;font-size: 17px;font-style: normal;font-variant: normal;font-weight: normal;letter-spacing: 0.544000029563904px;line-height: 27.2000007629395px;orphans: auto;text-transform: none;white-space: normal;widows: 1;word-spacing: 0px;-webkit-text-stroke-width: 0px;text-align: left;text-indent: -18pt;background-color: rgb(255, 255, 255);\"><span style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;color: rgb(0, 112, 192);font-size: 14px;\"><span style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;color: rgb(0, 112, 192);font-family: \u7b49\u7ebf;font-size: 14px;\">1.<\/span><span style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\">&nbsp;&nbsp;&nbsp;&nbsp;<\/span><span style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;color: rgb(0, 112, 192);font-family: \u7b49\u7ebf;font-size: 14px;\">\u4e00\u822c\u653e\u5728\u65e0\u83cc\u5de5\u827a\u6a21\u62df\u9a8c\u8bc1\uff0c\u5373\u57f9\u517b\u57fa\u704c\u88c5\uff08media fill runs\uff09\u671f\u95f4\u8fdb\u884c\u3002\u5f53\u7136\uff0c\u6bd5\u7adf\u57f9\u517b\u57fa\u704c\u88c5\u662f\u81f3\u5c11\u6bcf6\u4e2a\u6708\u4e00\u6b21\uff08\u4e00\u6b21\u4e0d\u7b49\u4e8e\u4e00\u4e2arun\uff09\uff0c\u6240\u4ee5\u5728\u8fd9\u4e2d\u95f4\uff0c\u5982\u9700\u8981\uff0c\u5355<\/span><\/span><span style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;color: rgb(0, 112, 192);font-family: \u7b49\u7ebf;font-size: 14px;\">\u72ec\u9488\u5bf9\u67d0\u4e00\u7ec4\u7279\u5b9a\u5185\u5305\u6750\u800c\u704c\u88c5\u57f9\u517b\u57fa\uff0c\u53d6\u6837\u7528\u4e8e\u5fae\u751f\u7269\u4fb5\u5165\u6d4b\u8bd5\u4e5f\u662f\u53ef\u4ee5\u7684\u3002<\/span><\/p>\n<p style=\"margin: 0px 0px 0px 24px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;clear: both;min-height: 1em;color: rgb(51, 51, 51);font-family: -apple-system-font, BlinkMacSystemFont, &#39;Helvetica Neue&#39;, &#39;PingFang SC&#39;, &#39;Hiragino Sans GB&#39;, &#39;Microsoft YaHei UI&#39;, &#39;Microsoft YaHei&#39;, Arial, sans-serif;font-size: 17px;font-style: normal;font-variant: normal;font-weight: normal;letter-spacing: 0.544000029563904px;line-height: 27.2000007629395px;orphans: auto;text-transform: none;white-space: normal;widows: 1;word-spacing: 0px;-webkit-text-stroke-width: 0px;text-align: left;text-indent: -18pt;background-color: rgb(255, 255, 255);\"><span style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;color: rgb(0, 112, 192);font-size: 14px;\"><span style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;color: rgb(0, 112, 192);font-family: \u7b49\u7ebf;font-size: 14px;\">2.<\/span><span style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\">&nbsp;&nbsp;&nbsp;&nbsp;<\/span><span style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;color: rgb(0, 112, 192);font-family: \u7b49\u7ebf;font-size: 14px;\">\u5982\u679c\u5728\u521d\u59cb\u9a8c\u8bc1\u540e\uff0c\u5f15\u5165\u65b0\u7684\u5185\u5305\u6750\uff0c\u5219\u5e94\u8003\u8651\u91cd\u65b0\u8fdb\u884c\u5bc6\u5c01\u53c2\u6570\u7684\u5f00\u53d1\u548c\u5bc6\u5c01\u6027\u9a8c\u8bc1\u3002<\/span><\/span><\/p>\n<p style=\"margin: 0px 0px 0px 24px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;clear: both;min-height: 1em;color: rgb(51, 51, 51);font-family: -apple-system-font, BlinkMacSystemFont, &#39;Helvetica Neue&#39;, &#39;PingFang SC&#39;, &#39;Hiragino Sans GB&#39;, &#39;Microsoft YaHei UI&#39;, &#39;Microsoft YaHei&#39;, Arial, sans-serif;font-size: 17px;font-style: normal;font-variant: normal;font-weight: normal;letter-spacing: 0.544000029563904px;line-height: 27.2000007629395px;orphans: auto;text-transform: none;white-space: normal;widows: 1;word-spacing: 0px;-webkit-text-stroke-width: 0px;text-align: left;text-indent: -18pt;background-color: rgb(255, 255, 255);\"><span style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;color: rgb(0, 112, 192);font-size: 14px;\"><span style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;color: rgb(0, 112, 192);font-family: \u7b49\u7ebf;font-size: 14px;\">3.<\/span><span style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\">&nbsp;&nbsp;&nbsp;&nbsp;<\/span><span style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;color: rgb(0, 112, 192);font-family: \u7b49\u7ebf;font-size: 14px;\">\u5185\u5305\u6750\uff08\u80f6\u585e\uff09\u706d\u83cc\u5de5\u827a\u53d1\u751f\u53d8\u5316\u65f6\uff0c\u5982\u589e\u52a0\u4e86\u706d\u83cc\u65f6\u95f4\uff0c\u6e29\u5ea6\u6216\u538b\u529b\uff0c\u4ee5\u53ca\u5185\u5305\u6750\u7684\u50a8\u5b58\u6761\u4ef6\u53d1\u751f\u660e\u663e\u53d8\u5316\u7684\u60c5\u51b5\u4e0b\uff0c\u5efa\u8bae\u589e\u52a0Microbial CCIT\u3002<\/span><\/span><span style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;color: rgb(0, 112, 192);\" lang=\"EN-US\"><\/span><\/p>\n<p style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;clear: both;min-height: 1em;color: rgb(51, 51, 51);font-family: -apple-system-font, BlinkMacSystemFont, &#39;Helvetica Neue&#39;, &#39;PingFang SC&#39;, &#39;Hiragino Sans GB&#39;, &#39;Microsoft YaHei UI&#39;, &#39;Microsoft YaHei&#39;, Arial, sans-serif;font-size: 17px;font-style: normal;font-variant: normal;font-weight: normal;letter-spacing: 0.544000029563904px;line-height: 27.2000007629395px;orphans: auto;text-indent: 0px;text-transform: none;white-space: normal;widows: 1;word-spacing: 0px;-webkit-text-stroke-width: 0px;text-align: left;background-color: rgb(255, 255, 255);\"><span style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;color: rgb(0, 112, 192);font-family: \u7b49\u7ebf;\" lang=\"EN-US\">&nbsp;<\/span><\/p>\n<p style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;clear: both;min-height: 1em;color: rgb(51, 51, 51);font-family: -apple-system-font, BlinkMacSystemFont, &#39;Helvetica Neue&#39;, &#39;PingFang SC&#39;, &#39;Hiragino Sans GB&#39;, &#39;Microsoft YaHei UI&#39;, &#39;Microsoft YaHei&#39;, Arial, sans-serif;font-size: 17px;font-style: normal;font-variant: normal;font-weight: normal;letter-spacing: 0.544000029563904px;line-height: 27.2000007629395px;orphans: auto;text-indent: 0px;text-transform: none;white-space: normal;widows: 1;word-spacing: 0px;-webkit-text-stroke-width: 0px;text-align: left;background-color: rgb(255, 255, 255);\"><span style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;color: rgb(0, 112, 192);font-family: \u7b49\u7ebf;font-size: 14px;\">\u5bb9\u5668\u5bc6\u5c01\u6027\u6d4b\u8bd5\u662f\u6210\u54c1\u7a33\u5b9a\u6027\u7814\u7a76\u7684\u4e00\u90e8\u5206\uff0c\u4e5f\u662f\u6210\u54c1\u65e0\u83cc\u68c0\u6d4b\u7684\u524d\u63d0\uff0c\u4f46\u4e0d\u80fd\u53d6\u4ee3\u6210\u54c1\u65e0\u83cc\u68c0\u6d4b\u3002<\/span><\/p>\n<p style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;clear: both;min-height: 1em;color: rgb(51, 51, 51);font-family: -apple-system-font, BlinkMacSystemFont, &#39;Helvetica Neue&#39;, &#39;PingFang SC&#39;, &#39;Hiragino Sans GB&#39;, &#39;Microsoft YaHei UI&#39;, &#39;Microsoft YaHei&#39;, Arial, sans-serif;font-size: 17px;font-style: normal;font-variant: normal;font-weight: normal;letter-spacing: 0.544000029563904px;line-height: 27.2000007629395px;orphans: auto;text-indent: 0px;text-transform: none;white-space: normal;widows: 1;word-spacing: 0px;-webkit-text-stroke-width: 0px;text-align: left;background-color: rgb(255, 255, 255);\"><span style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;color: rgb(0, 112, 192);font-family: \u7b49\u7ebf;font-size: 14px;\"><br style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/span><\/p>\n<p style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;clear: both;min-height: 1em;color: rgb(51, 51, 51);font-family: -apple-system-font, BlinkMacSystemFont, &#39;Helvetica Neue&#39;, &#39;PingFang SC&#39;, &#39;Hiragino Sans GB&#39;, &#39;Microsoft YaHei UI&#39;, &#39;Microsoft YaHei&#39;, Arial, sans-serif;font-size: 17px;font-style: normal;font-variant: normal;font-weight: normal;letter-spacing: 0.544000029563904px;line-height: 27.2000007629395px;orphans: auto;text-indent: 0px;text-transform: none;white-space: normal;widows: 1;word-spacing: 0px;-webkit-text-stroke-width: 0px;text-align: left;background-color: rgb(255, 255, 255);\"><span style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;color: rgb(0, 112, 192);font-family: \u7b49\u7ebf;font-size: 14px;\">\u4ee5\u4e0a\u57fa\u672c\u90fd\u662f\u5b9e\u9a8c\u5ba4\u68c0\u6d4b\uff0c\u6709\u4e9b\u662f\u7834\u574f\u6027\u7684\uff0c\u6709\u4e9b\u662f\u975e\u7834\u574f\u6027\u7684\u3002<\/span><\/p>\n<p style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;clear: both;min-height: 1em;color: rgb(51, 51, 51);font-family: -apple-system-font, BlinkMacSystemFont, &#39;Helvetica Neue&#39;, &#39;PingFang SC&#39;, &#39;Hiragino Sans GB&#39;, &#39;Microsoft YaHei UI&#39;, &#39;Microsoft YaHei&#39;, Arial, sans-serif;font-size: 17px;font-style: normal;font-variant: normal;font-weight: normal;letter-spacing: 0.544000029563904px;line-height: 27.2000007629395px;orphans: auto;text-indent: 0px;text-transform: none;white-space: normal;widows: 1;word-spacing: 0px;-webkit-text-stroke-width: 0px;text-align: left;background-color: rgb(255, 255, 255);\"><span style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;color: rgb(0, 112, 192);font-family: \u7b49\u7ebf;font-size: 14px;\"><br style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/span><\/p>\n<p style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;clear: both;min-height: 1em;color: rgb(51, 51, 51);font-family: -apple-system-font, BlinkMacSystemFont, &#39;Helvetica Neue&#39;, &#39;PingFang SC&#39;, &#39;Hiragino Sans GB&#39;, &#39;Microsoft YaHei UI&#39;, &#39;Microsoft YaHei&#39;, Arial, sans-serif;font-size: 17px;font-style: normal;font-variant: normal;font-weight: normal;letter-spacing: 0.544000029563904px;line-height: 27.2000007629395px;orphans: auto;text-indent: 0px;text-transform: none;white-space: normal;widows: 1;word-spacing: 0px;-webkit-text-stroke-width: 0px;text-align: left;background-color: rgb(255, 255, 255);\"><span style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;color: rgb(171, 25, 66);font-family: \u7b49\u7ebf;font-size: 14px;\">\u90a3\u9664\u4e86\u5b9e\u9a8c\u5ba4\u68c0\u6d4b\u5916\uff0c\u5728\u751f\u4ea7\u8fc7\u7a0b\u4e2d\u7684IPC\uff08in-process-control\uff09\u4e5f\u662f\u975e\u5e38\u91cd\u8981\u7684\u3002\u6709\u4e9b\u8bbe\u5907\u4f1a\u5728\u8bbe\u8ba1\u9636\u6bb5\u5c31\u5f15\u5165\u5728\u7ebf\u7684\u5bc6\u5c01\u6027\u68c0\u6d4b\uff0c\u5728\u7ebf\u68c0\u6d4b\u5fc5\u987b\u662f\u975e\u7834\u574f\u6027\u7684\u3002\u800c\u6ca1\u6709\u5728\u7ebf\u6d4b\u6f0f\u7684\u60c5\u51b5\u4e0b\uff0c\u901a\u5e38\u6211\u4eec\u4f1a\u5728\u6bcf\u6279\u7684\u751f\u4ea7\u8fc7\u7a0b\u4e2d\uff0c\u589e\u52a0\u76ee\u89c6\u68c0\u67e5\u5176\u5916\u89c2\u3002\u4ee5\u897f\u6797\u74f6\u4e3a\u4f8b\uff0c\u76ee\u68c0\u5176\u6709\u6ca1\u6709\u660e\u663e\u7684\u5bc6\u5c01\u6027\u95ee\u9898\uff08\u80f6\u585e\u4e0d\u5728\u4f4d\uff0c\u4f4d\u7f6e\u660e\u663e\u4e0d\u5bf9\uff0c\u94dd\u76d6\u5305\u8fb9\u4e0d\u591f\u7b49\u7b49\uff09\uff0c\u518d\u52a0\u4e0a\u624b\u52a8\u968f\u673a\u62bd\u53d6\u8f67\u76d6\u540e\u7684\u74f6\u5b50\u8fdb\u884c\u6d4b\u8bd5\uff0c\u5982\u8457\u540d\u7684\u201c\u4e09\u6307\u6cd5\u201d\u3002\u8fd9\u4e2a\u4e09\u6307\u6cd5\u5e76\u4e0d\u79d1\u5b66\uff0c\u56e0\u4e3a\u6bcf\u4e2a\u4eba\u7684\u624b\u52b2\u662f\u4e0d\u540c\u7684\uff0c\u5373\u4fbf\u540c\u4e00\u4e2a\u4eba\u53ef\u91cd\u590d\u6027\u4e5f\u6bd4\u8f83\u5dee\uff0c\u4e0d\u8fc7\u5bf9\u660e\u663e\u7684\u677e\u52a8\uff0c\u8fd9\u4e2a\u65b9\u6cd5\u8fd8\u662f\u53ef\u4ee5\u7684\u3002\u800c\u6bd4\u8f83\u79d1\u5b66\u7684\u662f\u7528\u6b8b\u7559\u529b\u6216\u8005\u626d\u529b\u77e9\u68c0\u6d4b\u4eea\u6765\u68c0\u67e5\u6709\u6ca1\u6709\u660e\u663e\u7684\u5bc6\u5c01\u6027\u95ee\u9898\uff08\u4e2a\u4eba\u8ba4\u4e3a\uff0c\u626d\u529b\u8fd8\u662f\u66f4\u9002\u7528\u4e8e\u87ba\u7eb9\u53e3\uff0c\u5bf9\u94dd\u5851\u76d6\u8fd9\u79cd\u6d4b\u6b8b\u7559\u529b\u76f8\u5bf9\u66f4\u52a0\u5408\u7406\uff09\u3002\u5f53\u7136\uff0c\u8fd9\u53ea\u80fd\u4f5c\u4e3aIPC \u7684\u4e00\u90e8\u5206\uff0c\u4e5f\u65e0\u6cd5\u68c0\u6d4b\u51fa\u5fae\u6f0f\u3002\u66f4\u4e0d\u80fd\u53d6\u4ee3\u5b9e\u9a8c\u5ba4\u68c0\u6d4b\uff01<\/span><\/p>\n<p style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;clear: both;min-height: 1em;color: rgb(51, 51, 51);font-family: -apple-system-font, BlinkMacSystemFont, &#39;Helvetica Neue&#39;, &#39;PingFang SC&#39;, &#39;Hiragino Sans GB&#39;, &#39;Microsoft YaHei UI&#39;, &#39;Microsoft YaHei&#39;, Arial, sans-serif;font-size: 17px;font-style: normal;font-variant: normal;font-weight: normal;letter-spacing: 0.544000029563904px;line-height: 27.2000007629395px;orphans: auto;text-align: justify;text-indent: 0px;text-transform: none;white-space: normal;widows: 1;word-spacing: 0px;-webkit-text-stroke-width: 0px;background-color: rgb(255, 255, 255);\"><span style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;color: rgb(0, 112, 192);font-family: \u7b49\u7ebf;font-size: 14px;\"><\/span><\/p>\n<p style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;clear: both;min-height: 1em;color: rgb(51, 51, 51);font-family: -apple-system-font, BlinkMacSystemFont, &#39;Helvetica Neue&#39;, &#39;PingFang SC&#39;, &#39;Hiragino Sans GB&#39;, &#39;Microsoft YaHei UI&#39;, &#39;Microsoft YaHei&#39;, Arial, sans-serif;font-size: 17px;font-style: normal;font-variant: normal;font-weight: normal;letter-spacing: 0.544000029563904px;line-height: 27.2000007629395px;orphans: auto;text-align: justify;text-indent: 0px;text-transform: none;white-space: normal;widows: 1;word-spacing: 0px;-webkit-text-stroke-width: 0px;background-color: rgb(255, 255, 255);\"><br style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/p>\n<p style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;clear: both;min-height: 1em;color: rgb(51, 51, 51);font-family: -apple-system-font, BlinkMacSystemFont, &#39;Helvetica Neue&#39;, &#39;PingFang SC&#39;, &#39;Hiragino Sans GB&#39;, &#39;Microsoft YaHei UI&#39;, &#39;Microsoft YaHei&#39;, Arial, sans-serif;font-size: 17px;font-style: normal;font-variant: normal;font-weight: normal;letter-spacing: 0.544000029563904px;line-height: 27.2000007629395px;orphans: auto;text-align: justify;text-indent: 0px;text-transform: none;white-space: normal;widows: 1;word-spacing: 0px;-webkit-text-stroke-width: 0px;background-color: rgb(255, 255, 255);\"><br style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/p>\n<p style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;clear: both;min-height: 1em;color: rgb(51, 51, 51);font-family: -apple-system-font, BlinkMacSystemFont, &#39;Helvetica Neue&#39;, &#39;PingFang SC&#39;, &#39;Hiragino Sans GB&#39;, &#39;Microsoft YaHei UI&#39;, &#39;Microsoft YaHei&#39;, Arial, sans-serif;font-size: 17px;font-style: normal;font-variant: normal;font-weight: normal;letter-spacing: 0.544000029563904px;line-height: 27.2000007629395px;orphans: auto;text-indent: 0px;text-transform: none;white-space: normal;widows: 1;word-spacing: 0px;-webkit-text-stroke-width: 0px;text-align: left;background-color: rgb(255, 255, 255);\"><span style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;font-size: 14px;\"><strong style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"><em style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;font-style: italic;\"><span style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;font-family: \u7b49\u7ebf;text-decoration: underline;\">\u6709\u5173\u6cc4\u6f0f\u7387\u7684\u4e00\u4e9b\u6807\u51c6\uff08USP\uff09<\/span><\/em><\/strong><\/span><\/p>\n<p style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;clear: both;min-height: 1em;color: rgb(51, 51, 51);font-family: -apple-system-font, BlinkMacSystemFont, &#39;Helvetica Neue&#39;, &#39;PingFang SC&#39;, &#39;Hiragino Sans GB&#39;, &#39;Microsoft YaHei UI&#39;, &#39;Microsoft YaHei&#39;, Arial, sans-serif;font-size: 17px;font-style: normal;font-variant: normal;font-weight: normal;letter-spacing: 0.544000029563904px;line-height: 27.2000007629395px;orphans: auto;text-indent: 0px;text-transform: none;white-space: normal;widows: 1;word-spacing: 0px;-webkit-text-stroke-width: 0px;text-align: left;background-color: rgb(255, 255, 255);\"><span style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;font-family: \u7b49\u7ebf;font-size: 14px;\">&nbsp;<\/span><\/p>\n<p style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;clear: both;min-height: 1em;color: rgb(51, 51, 51);font-family: -apple-system-font, BlinkMacSystemFont, &#39;Helvetica Neue&#39;, &#39;PingFang SC&#39;, &#39;Hiragino Sans GB&#39;, &#39;Microsoft YaHei UI&#39;, &#39;Microsoft YaHei&#39;, Arial, sans-serif;font-size: 17px;font-style: normal;font-variant: normal;font-weight: normal;letter-spacing: 0.544000029563904px;line-height: 27.2000007629395px;orphans: auto;text-indent: 0px;text-transform: none;white-space: normal;widows: 1;word-spacing: 0px;-webkit-text-stroke-width: 0px;text-align: left;background-color: rgb(255, 255, 255);\"><span style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;font-size: 14px;\"><em style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;font-style: italic;\"><span style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;font-family: \u7b49\u7ebf;font-size: 14px;\">USP 38-1207 states that \u201cConsiderable published research exists exploring rigid package leaks and their relationship to risk of aqueous solution leakage and\/or microbial ingress. A key study series found orifice leaks of approximately 0.1 \u03bcmin nominal diameter (using micropipettes) placed in rigid packages demonstrate a small risk of aqueous liquid passage, while orifice leaks as small as approximately 0.3 \u03bcmin nominal diameter first demonstrate some risk of microbial ingress by liquid challenge (2,3). For a summary of similar studies comparing risks of microbial ingress and liquid leakage to leak size and type, the reader may refer to reference 4.\u201d<\/span><\/em><\/span><\/p>\n<p style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;clear: both;min-height: 1em;color: rgb(51, 51, 51);font-family: -apple-system-font, BlinkMacSystemFont, &#39;Helvetica Neue&#39;, &#39;PingFang SC&#39;, &#39;Hiragino Sans GB&#39;, &#39;Microsoft YaHei UI&#39;, &#39;Microsoft YaHei&#39;, Arial, sans-serif;font-size: 17px;font-style: normal;font-variant: normal;font-weight: normal;letter-spacing: 0.544000029563904px;line-height: 27.2000007629395px;orphans: auto;text-indent: 0px;text-transform: none;white-space: normal;widows: 1;word-spacing: 0px;-webkit-text-stroke-width: 0px;text-align: left;background-color: rgb(255, 255, 255);\"><span style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;font-size: 14px;\"><em style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;font-style: italic;\"><span style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;font-family: \u7b49\u7ebf;\">Given this body of evidence, a maximum allowable leakage limit of less than 6 \u00d710<\/span><\/em><em style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;font-style: italic;\"><sup style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\">\u2212<\/sup><span style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;font-family: \u7b49\u7ebf;\"><sup style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\">6<\/sup><\/span>mbar \u00b7 L\/s(measured by helium mass spectrometry in the vacuum mode) can be adopted for products in this category packaged in rigid container\u2013closure systems. This leakage rate equates to the presence of an orifice of nominal diameter of between 0.1 and 0.3 \u03bcm. At this leakage rate, the probability of microbia ingress was determined to be &lt;0.10 (2). Selecting this conservative maximum allowable leakage limit will ensure a low risk of microbial ingress and liquid leakage and can eliminate the need to perform additional microbial ingress or liquid challenge studies as a function of leak size.<\/em><\/span><\/p>\n<p style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;clear: both;min-height: 1em;color: rgb(51, 51, 51);font-family: -apple-system-font, BlinkMacSystemFont, &#39;Helvetica Neue&#39;, &#39;PingFang SC&#39;, &#39;Hiragino Sans GB&#39;, &#39;Microsoft YaHei UI&#39;, &#39;Microsoft YaHei&#39;, Arial, sans-serif;font-size: 17px;font-style: normal;font-variant: normal;font-weight: normal;letter-spacing: 0.544000029563904px;line-height: 27.2000007629395px;orphans: auto;text-align: justify;text-indent: 0px;text-transform: none;white-space: normal;widows: 1;word-spacing: 0px;-webkit-text-stroke-width: 0px;background-color: rgb(255, 255, 255);\"><br style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/p>\n<p style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;clear: both;min-height: 1em;color: rgb(51, 51, 51);font-family: -apple-system-font, BlinkMacSystemFont, &#39;Helvetica Neue&#39;, &#39;PingFang SC&#39;, &#39;Hiragino Sans GB&#39;, &#39;Microsoft YaHei UI&#39;, &#39;Microsoft YaHei&#39;, Arial, sans-serif;font-size: 17px;font-style: normal;font-variant: normal;font-weight: normal;letter-spacing: 0.544000029563904px;line-height: 27.2000007629395px;orphans: auto;text-align: justify;text-indent: 0px;text-transform: none;white-space: normal;widows: 1;word-spacing: 0px;-webkit-text-stroke-width: 0px;background-color: rgb(255, 255, 255);\"><span style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;text-align: left;color: rgb(136, 136, 136);text-transform: none;text-indent: 0px;letter-spacing: normal;font-size: 14px;font-style: normal;font-variant: normal;font-weight: 400;text-decoration: none;word-spacing: 0px;orphans: 2;-webkit-text-stroke-width: 0px;background-color: transparent;\">\u58f0\u660e\uff1a\u4e2a\u4eba\u89c2\u70b9\uff0c\u4ec5\u4f9b\u53c2\u8003\u3002\u8c28\u4ee5\u6b64\u516c\u4f17\u53f7\u63d0\u4f9b\u4e00\u4e2a\u4e92\u76f8\u5206\u4eab\u548c\u5b66\u4e60\u7684\u5e73\u53f0\u3002\u6b22\u8fce\u5404\u4f4d\u540c\u884c\uff0c\u4e13\u5bb6\uff0c\u5927\u725b\u79c1\u4fe1\uff0c\u7559\u8a00\uff0c\u63d0\u4f9b\u4e0d\u540c\u89c1\u89e3\uff0c\u5206\u4eab\u76f8\u5173\u6280\u672f\u8d44\u6599\u3002<\/span><\/p>\n<p style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;clear: both;min-height: 1em;color: rgb(51, 51, 51);font-family: -apple-system-font, BlinkMacSystemFont, &#39;Helvetica Neue&#39;, &#39;PingFang SC&#39;, &#39;Hiragino Sans GB&#39;, &#39;Microsoft YaHei UI&#39;, &#39;Microsoft YaHei&#39;, Arial, sans-serif;font-size: 17px;font-style: normal;font-variant: normal;font-weight: normal;letter-spacing: 0.544000029563904px;line-height: 27.2000007629395px;orphans: auto;text-align: justify;text-indent: 0px;text-transform: none;white-space: normal;widows: 1;word-spacing: 0px;-webkit-text-stroke-width: 0px;background-color: rgb(255, 255, 255);\"><br style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/p>\n<p style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;clear: both;min-height: 1em;color: rgb(51, 51, 51);font-family: -apple-system-font, BlinkMacSystemFont, &#39;Helvetica Neue&#39;, &#39;PingFang SC&#39;, &#39;Hiragino Sans GB&#39;, &#39;Microsoft YaHei UI&#39;, &#39;Microsoft YaHei&#39;, Arial, sans-serif;font-size: 17px;font-style: normal;font-variant: normal;font-weight: normal;letter-spacing: 0.544000029563904px;line-height: 27.2000007629395px;orphans: auto;text-indent: 0px;text-transform: none;white-space: normal;widows: 1;word-spacing: 0px;-webkit-text-stroke-width: 0px;text-align: left;background-color: rgb(255, 255, 255);\"><span style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;font-size: 12px;\"><span style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;font-family: \u7b49\u7ebf;\">\u53c2\u8003\u6587\u732e\uff1a<\/span><span style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\" lang=\"EN-US\"><\/span><\/span><\/p>\n<p style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;clear: both;min-height: 1em;color: rgb(51, 51, 51);font-family: -apple-system-font, BlinkMacSystemFont, &#39;Helvetica Neue&#39;, &#39;PingFang SC&#39;, &#39;Hiragino Sans GB&#39;, &#39;Microsoft YaHei UI&#39;, &#39;Microsoft YaHei&#39;, Arial, sans-serif;font-size: 17px;font-style: normal;font-variant: normal;font-weight: normal;letter-spacing: 0.544000029563904px;line-height: 27.2000007629395px;orphans: auto;text-indent: 0px;text-transform: none;white-space: normal;widows: 1;word-spacing: 0px;-webkit-text-stroke-width: 0px;text-align: left;background-color: rgb(255, 255, 255);\"><span style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;font-family: \u7b49\u7ebf;font-size: 12px;\">[1] Guidance for Industry Sterile Drug Products Produced by Aseptic Processing<\/span><\/p>\n<p style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;clear: both;min-height: 1em;color: rgb(51, 51, 51);font-family: -apple-system-font, BlinkMacSystemFont, &#39;Helvetica Neue&#39;, &#39;PingFang SC&#39;, &#39;Hiragino Sans GB&#39;, &#39;Microsoft YaHei UI&#39;, &#39;Microsoft YaHei&#39;, Arial, sans-serif;font-size: 17px;font-style: normal;font-variant: normal;font-weight: normal;letter-spacing: 0.544000029563904px;line-height: 27.2000007629395px;orphans: auto;text-indent: 0px;text-transform: none;white-space: normal;widows: 1;word-spacing: 0px;-webkit-text-stroke-width: 0px;text-align: left;background-color: rgb(255, 255, 255);\"><span style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;font-family: \u7b49\u7ebf;font-size: 12px;\">[2] ISO 8362<\/span><\/p>\n<p style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;clear: both;min-height: 1em;color: rgb(51, 51, 51);font-family: -apple-system-font, BlinkMacSystemFont, &#39;Helvetica Neue&#39;, &#39;PingFang SC&#39;, &#39;Hiragino Sans GB&#39;, &#39;Microsoft YaHei UI&#39;, &#39;Microsoft YaHei&#39;, Arial, sans-serif;font-size: 17px;font-style: normal;font-variant: normal;font-weight: normal;letter-spacing: 0.544000029563904px;line-height: 27.2000007629395px;orphans: auto;text-indent: 0px;text-transform: none;white-space: normal;widows: 1;word-spacing: 0px;-webkit-text-stroke-width: 0px;text-align: left;background-color: rgb(255, 255, 255);\"><span style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;font-family: \u7b49\u7ebf;font-size: 12px;\">[3] USP 1207<\/span><\/p>\n<p style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;clear: both;min-height: 1em;color: rgb(51, 51, 51);font-family: -apple-system-font, BlinkMacSystemFont, &#39;Helvetica Neue&#39;, &#39;PingFang SC&#39;, &#39;Hiragino Sans GB&#39;, &#39;Microsoft YaHei UI&#39;, &#39;Microsoft YaHei&#39;, Arial, sans-serif;font-size: 17px;font-style: normal;font-variant: normal;font-weight: normal;letter-spacing: 0.544000029563904px;line-height: 27.2000007629395px;orphans: auto;text-indent: 0px;text-transform: none;white-space: normal;widows: 1;word-spacing: 0px;-webkit-text-stroke-width: 0px;text-align: left;background-color: rgb(255, 255, 255);\"><span style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;font-family: \u7b49\u7ebf;font-size: 12px;\">[4] Kirsch, L. E.; Nguyen, L.; Moeckly, C. S.; Gerth, R. Pharmaceutical container\/closure integrity. II: The relationship between microbial ingress and helium leak rates in rubber-stoppered glass vials. PDA J. Pharm. Sci. Technol. 1997, 51 (5), 195\u2013202.<\/span><\/p>\n<p style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;clear: both;min-height: 1em;color: rgb(51, 51, 51);font-family: -apple-system-font, BlinkMacSystemFont, &#39;Helvetica Neue&#39;, &#39;PingFang SC&#39;, &#39;Hiragino Sans GB&#39;, &#39;Microsoft YaHei UI&#39;, &#39;Microsoft YaHei&#39;, Arial, sans-serif;font-size: 17px;font-style: normal;font-variant: normal;font-weight: normal;letter-spacing: 0.544000029563904px;line-height: 27.2000007629395px;orphans: auto;text-indent: 0px;text-transform: none;white-space: normal;widows: 1;word-spacing: 0px;-webkit-text-stroke-width: 0px;text-align: left;background-color: rgb(255, 255, 255);\"><span style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;font-family: \u7b49\u7ebf;font-size: 12px;\">[5] Gilchrist, J. E., U. S. Rhea, R. W. Dickerson and J. E. Campbell. 1985. Helium leak test for micron-sized holes in canned foods. J. Food Prot. 48(10):856-860.<\/span><\/p>\n<p style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;clear: both;min-height: 1em;color: rgb(51, 51, 51);font-family: -apple-system-font, BlinkMacSystemFont, &#39;Helvetica Neue&#39;, &#39;PingFang SC&#39;, &#39;Hiragino Sans GB&#39;, &#39;Microsoft YaHei UI&#39;, &#39;Microsoft YaHei&#39;, Arial, sans-serif;font-size: 17px;font-style: normal;font-variant: normal;font-weight: normal;letter-spacing: 0.544000029563904px;line-height: 27.2000007629395px;orphans: auto;text-indent: 0px;text-transform: none;white-space: normal;widows: 1;word-spacing: 0px;-webkit-text-stroke-width: 0px;text-align: left;background-color: rgb(255, 255, 255);\"><span style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;font-family: \u7b49\u7ebf;font-size: 12px;\">[6] McEldowney, S. and M. Fletcher. 1990a. A model system for the study of food container leakage. J. Appl. Bacteriol. 69:206-210.<\/span><\/p>\n<p style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;min-height: 1em;color: rgb(51, 51, 51);\"><span style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;font-family: \u7b49\u7ebf;font-size: 12px;\">[7] Scott W. Keller. Determination of the leak size critical to package sterility maintenance. Doctor of Philosophy research paper. August 1998: 155<\/span><span style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;font-family: \u7b49\u7ebf;font-size: 14px;\">.<\/span><\/p>\n<blockquote class='keep-source'>\n<p>\u59cb\u53d1\u4e8e\u5fae\u4fe1\u516c\u4f17\u53f7\uff1a                                               <\/p>\n<\/blockquote>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>\u5bb9\u5668\u5bc6\u5c01\u6027 (CCIT \u2013Container Closure Integrity Test)\uff0c\u987e\u540d\u601d\u4e49\u5c31\u662f\u68c0\u67e5 [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":11362,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[2],"tags":[],"_links":{"self":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/11361"}],"collection":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/comments?post=11361"}],"version-history":[{"count":1,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/11361\/revisions"}],"predecessor-version":[{"id":11364,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/11361\/revisions\/11364"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/media\/11362"}],"wp:attachment":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/media?parent=11361"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/categories?post=11361"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/tags?post=11361"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}