{"id":117702,"date":"2019-06-12T03:50:50","date_gmt":"2020-04-20T09:52:14","guid":{"rendered":"http:\/\/www.05921.net\/index.php\/117702\/"},"modified":"2020-04-20T17:52:15","modified_gmt":"2020-04-20T09:52:15","slug":"99e9e202f1","status":"publish","type":"post","link":"https:\/\/www.05921.net\/index.php\/117702\/","title":{"rendered":"\u8d3a\u5efa\u594e 2.0 \u6765\u4e86\uff0c\u4ed6\u8981\u5236\u9020\u66f4\u591a\u7684\u57fa\u56e0\u7f16\u8f91\u5a74\u513f"},"content":{"rendered":"
\n
<\/section>\n

6 \u6708 10 \u65e5\uff0c\u636e Nature \u62a5\u9053\uff0c\u4fc4\u7f57\u65af\u79d1\u5b66\u5bb6 Denis Rebrikov \u8868\u793a\u4ed6\u8ba1\u5212\u5236\u9020\u66f4\u591a\u57fa\u56e0\u7f16\u8f91\u7684\u5a74\u513f\u3002<\/span><\/p>\n


<\/p>\n

\u4ed6\u8981\u6210\u4e3a\u6539\u8fdb\u7248\u8d3a\u5efa\u594e\uff0c\u5c06\u5bf9\u6297\u827e\u6ecb\u75c5\u7684\u57fa\u56e0\u7f16\u8f91\u5a74\u513f\u5b9e\u9a8c\u8fdb\u884c\u4e0b\u53bb\u3002<\/span><\/p>\n


<\/p>\n

\"\u8d3a\u5efa\u594e<\/span> Nature \u62a5\u9053\u622a\u56fe<\/span><\/span><\/p>\n


<\/p>\n

 <\/span><\/p>\n


<\/span><\/p>\n

\u8d3a\u6c0f\u7814\u7a76\u6539\u8fdb\u7248<\/span><\/strong>
<\/p>\n


<\/p>\n

\u4fc4\u56fd\u79d1\u5b66\u5bb6 Rebrikov <\/span>\u662f\u7b2c\u4e8c\u4e2a\u5403\u8fd9\u79cd\u8783\u87f9\u7684\u4eba\u3002<\/span><\/p>\n


<\/span><\/p>\n

2018 \u5e74 11 \u6708\uff0c\u8d3a\u5efa\u594e\u5ba3\u5e03\u4ed6\u521b\u9020\u4e86\u4e16\u754c\u4e0a\u7b2c\u4e00\u6279\u57fa\u56e0\u7f16\u8f91\u5a74\u513f\uff0c\u4e00\u5ea6\u5f15\u8d77\u56fd\u9645\u793e\u4f1a\u7684\u5f3a\u70c8\u6297\u8bae\u3002\u8d3a\u6c0f\u7814\u7a76\u4e5f\u88ab\u79d1\u5b66\u754c\u786e\u8ba4\u5931\u8d25\u3002<\/span><\/p>\n


<\/p>\n

\u8fd9\u6b21\uff0cRebrikov \u58f0\u79f0\u4ed6\u7684\u6280\u672f\u4f1a\u5e26\u6765\u66f4\u5927\u7684\u597d\u5904\u3001\u66f4\u5c11\u7684\u98ce\u9669\u3001\u66f4\u7b26\u5408\u9053\u5fb7\u89c4\u8303\u3001\u66f4\u80fd\u4e3a\u516c\u4f17\u6240\u63a5\u53d7\u3002<\/span>\u4ed6\u5bf9 Nature \u8868\u793a\uff0c\u5982\u679c\u80fd\u5728\u5e74\u5e95\u524d\u83b7\u6279\u7684\u8bdd\uff0c\u4ed6\u7684\u5b9e\u9a8c\u4f1a\u5728\u4eca\u5e74\u5e74\u5e95\u524d\u5b8c\u6210\u3002<\/span><\/p>\n


<\/span><\/p>\n

\u548c\u8d3a\u5efa\u594e\u4e00\u6837\uff0c\u4ed6\u4e5f\u8981\u5bf9 CCR5 \u57fa\u56e0\u8fdb\u884c\u7f16\u8f91\uff0c\u4ee5\u964d\u4f4e\u5a74\u513f\u611f\u67d3 HIV \u7684\u98ce\u9669\u3002<\/span><\/strong><\/span><\/p>\n


<\/span><\/p>\n

CCR5 \u57fa\u56e0\u7f16\u7801\u662f\u4e00\u79cd\u5141\u8bb8 HIV \u8fdb\u5165\u7ec6\u80de\u7684\u86cb\u767d\u8d28\uff0cRebrikov \u8ba1\u5212\u8ba9\u80da\u80ce\u7684 CCR5 \u57fa\u56e0\u5931\u6d3b\uff0c\u7136\u540e\u5c06\u80da\u80ce\u690d\u5165 HIV \u9633\u6027\u7684\u6bcd\u4f53\uff0c\u4ece\u800c\u964d\u4f4e HIV \u6bcd\u4eb2\u5c06\u75c5\u6bd2\u4f20\u67d3\u7ed9\u5b50\u5bab\u5185\u5a74\u513f\u7684\u98ce\u9669\u3002<\/span><\/p>\n


<\/p>\n

\u4e0e\u8d3a\u5efa\u594e\u7684\u4e0d\u540c\u662f\uff0cRebrikov <\/span>\u8981\u5c06\u57fa\u56e0\u7f16\u8f91\u8fc7\u7684\u80da\u80ce\u690d\u5165\u5973\u6027\u827e\u6ecb\u75c5\u60a3\u8005\u4f53\u5185\uff0c\u800c\u6b64\u524d\u8d3a\u5efa\u594e\u4fee\u6539\u7684\u662f\u7236\u4eb2\u643a\u5e26\u827e\u6ecb\u75c5\u6bd2\u7684\u80da\u80ce\u57fa\u56e0\u3002<\/span>\u8bb8\u591a\u9057\u4f20\u5b66\u5bb6\u90fd\u8ba4\u4e3a\uff0c\u8d3a\u5efa\u594e\u505a\u4e86\u4e00\u4efd\u65e0\u7528\u529f\uff0c\u4ed6\u7684\u5b9e\u9a8c\u5bf9\u8c61\uff08\u5373\u53d7\u5b55\u5973\u6027\uff09\u5e76\u6ca1\u6709\u611f\u67d3 HIV\uff0c\u53ea\u6709\u5b55\u5987\u7684\u4e08\u592b\u662f\u827e\u6ecb\u75c5\u60a3\u8005\uff0c\u800c\u7236\u4eb2\u5c06 HIV \u4f20\u7ed9\u5b50\u5973\u7684\u98ce\u9669\u5f88\u5c0f\u3002<\/span><\/p>\n


<\/p>\n

\u6839\u636e Rebrikov \u7684\u8bf4\u6cd5\uff0c\u4ed6\u5df2\u7ecf\u4e0e\u8be5\u5e02\u7684\u4e00\u4e2a\u827e\u6ecb\u75c5\u6bd2\u4e2d\u5fc3\u8fbe\u6210\u4e86\u534f\u8bae\uff0c\u62db\u52df\u90a3\u4e9b\u611f\u67d3 HIV \u60f3\u8981\u53c2\u52a0\u5b9e\u9a8c\u7684\u5973\u6027\u3002<\/span><\/p>\n


<\/p>\n

 <\/span><\/p>\n


<\/p>\n

Denis Rebrikov \u662f\u8c01\uff1f<\/strong><\/span><\/p>\n


<\/p>\n

\u591a\u5e74\u6765\uff0c\u4fc4\u7f57\u65af\u4e00\u76f4\u662f\u751f\u7269\u6280\u672f\u53d1\u5c55\u7684\u6d3c\u5730\uff0c\u5176\u751f\u7269\u6280\u672f\u9886\u57df\u7684\u53d1\u5c55\u4e5f\u5f88\u5c11\u767b\u4e0a\u65b0\u95fb\u5934\u6761\u3002DeepTech \u54a8\u8be2\u4e86\u591a\u4f4d\u57fa\u56e0\u7f16\u8f91\u7b49\u751f\u7269\u6280\u672f\u9886\u57df\u7684\u4e13\u5bb6\uff0c\u4ed6\u4eec\u5747\u8868\u793a\u4e0e\u4fc4\u7f57\u65af\u5b66\u8005\u5f88\u5c11\u63a5\u89e6\uff0c\u5e76\u77e5\u4e4b\u751a\u5c11\u3002<\/span><\/p>\n


<\/p>\n

Rebrikov \u662f\u4fc4\u7f57\u65af\u6700\u5927\u7684\u751f\u80b2\u8bca\u6240\u2014\u2014Kulakov \u56fd\u5bb6\u5987\u4ea7\u79d1\u548c\u56f4\u4ea7\u513f\u533b\u5b66\u7814\u7a76\u4e2d\u5fc3\u57fa\u56e0\u7ec4\u7f16\u8f91\u5b9e\u9a8c\u5ba4\u7684\u8d1f\u8d23\u4eba\uff0c\u4e5f\u662f\u4fc4\u7f57\u65af\u56fd\u7acb\u76ae\u7f57\u6208\u592b\u533b\u79d1\u5927\u5b66\u526f\u6821\u957f\u3002<\/span><\/p>\n


<\/p>\n

\"\u8d3a\u5efa\u594e<\/p>\n

\u4fc4\u7f57\u65af\u79d1\u5b66\u5bb6 Denis Rebrikov<\/span><\/p>\n

\uff08\u56fe\u6e90\uff1aNature\uff09<\/span><\/p>\n


<\/p>\n

\u4ed6\u662f\u9057\u4f20\u5b66\u535a\u58eb\uff0c\u4e3b\u8981\u7814\u7a76\u9886\u57df\u4e3a\u5206\u5b50\u751f\u7269\u5b66\u548c\u57fa\u56e0\u5de5\u7a0b\uff0c\u8d1f\u8d23\u4eba\u7c7b\u57fa\u56e0\u7ec4\u548c\u5fae\u751f\u7269\u7ec4\u7814\u7a76\uff0c\u6d89\u53ca\u533b\u5b66\u8bca\u65ad\u3001\u57fa\u56e0\u5206\u578b\u3001\u8f6c\u57fa\u56e0\u751f\u7269\u68c0\u6d4b\u3001DNA \u6307\u7eb9\u5206\u6790\u548c\u57fa\u56e0\u7ec4\u7f16\u8f91\u7b49\u6280\u672f\u3002<\/span><\/p>\n


<\/p>\n

\u4e8b\u5b9e\u4e0a\uff0cRebrikov \u7684\u57fa\u56e0\u7f16\u8f91\u5a74\u513f\u60f3\u6cd5\u5e76\u975e\u6fc0\u60c5\u800c\u4e3a\uff0c\u751a\u81f3\u4ed6\u7684\u60f3\u6cd5\u5f88\u53ef\u80fd\u5e76\u975e\u53d7\u8d3a\u5efa\u594e\u542f\u53d1\u3002<\/span><\/strong><\/span><\/p>\n


<\/p>\n

\u636e\u4fc4\u7f57\u65af\u536b\u661f\u901a\u8baf\u793e 2018 \u5e74 10 \u6708 29 \u65e5\u7684\u62a5\u9053\uff0cRebrikov \u5df2\u7ecf\u5236\u9020\u4e86\u5bf9\u6297 HIV \u57fa\u56e0\u7f16\u8f91<\/span>\u300c<\/strong>\u80da\u80ce\u300d<\/strong><\/span>\uff0c\u4ed6\u4eec\u5229\u7528 CRISPR-Cas9 \u7cfb\u7edf\u5728\u53d7\u7cbe\u5375\u9636\u6bb5\u4fee\u6539\u4e86\u80da\u80ce\uff0c\u5373\u5220\u53bb\u4e86 CCR5 \u57fa\u56e0\u5e8f\u5217\u4e2d\u7684 32 \u4e2a\u78b1\u57fa\u5bf9\u3002\u6b64\u65f6\u8ddd\u79bb\u8d3a\u5efa\u594e\u516c\u5f00\u5176\u57fa\u56e0\u7f16\u8f91\u5a74\u513f\u7814\u7a76\u8fd8\u6709\u4e00\u4e2a\u6708\u65f6\u95f4\u3002<\/span><\/p>\n


<\/p>\n

\u5f7c\u65f6\uff0cRebrikov \u8fd8\u6ca1\u6709\u51c6\u5907\u5236\u9020\u57fa\u56e0\u7f16\u8f91<\/span>\u300c<\/span><\/strong>\u5a74\u513f\u300d<\/strong><\/span>\u3002<\/span><\/p>\n


<\/span><\/p>\n

\u4ed6\u5728\u63a5\u53d7\u4fc4\u7f57\u65af\u536b\u661f\u901a\u8baf\u793e\u91c7\u8bbf\u65f6\u63d0\u53ca 2015 \u5e74\u4e2d\u5c71\u5927\u5b66\u9ec4\u519b\u5c31\u5229\u7528\u57fa\u56e0\u7f16\u8f91\u6280\u672f\u6cbb\u7597\u5730\u4e2d\u6d77\u8d2b\u8840\u7684\u7814\u7a76\uff0c\u4ed6\u8ba4\u4e3a\uff0c\u5728\u80da\u80ce\u6c34\u5e73\u4e0a\uff0c\u6539\u53d8\u4eba\u7c7b\u57fa\u56e0\u7ec4\u662f\u4e00\u4e2a\u65b0\u7684\u65b9\u5411\uff0c\u65e2\u6ca1\u6709\u9002\u5f53\u7684\u7acb\u6cd5\u57fa\u7840\uff0c\u4e5f\u6ca1\u6709\u8db3\u591f\u7684\u516c\u4f17\u8ba4\u77e5\u3002<\/span><\/p>\n


<\/p>\n

Rebrikov \u8fd8\u8bf4\uff0c\u5bf9\u4e8e\u80da\u80ce\u6c34\u5e73\u7684\u57fa\u56e0\u7f16\u8f91\u800c\u8a00\uff0c\u4eca\u5929\u5e76\u6ca1\u6709\u90a3\u4e48\u591a\u7684\u533b\u5b66\u76ee\u6807\u3002\u53ea\u6709\u5355\u57fa\u56e0\u9057\u4f20\u7684\u75be\u75c5\uff0c\u624d\u80fd\u901a\u8fc7\u6539\u53d8\u57fa\u56e0\u7ec4\u5728\u4f53\u5916\u53d7\u7cbe\u80da\u80ce\u4e2d\u8fdb\u884c\u9009\u62e9\u3002<\/span><\/p>\n


<\/p>\n

\u4e8e\u662f Rebrikov \u628a\u76ee\u5149\u7784\u5411\u4e86\u6297 HIV \u80da\u80ce\u3002\u4ed6\u5728 2018 \u5e74\u8fd9\u6b21\u91c7\u8bbf\u4e2d\u8ba4\u4e3a\uff0cCCR5 \u57fa\u56e0\u7f16\u8f91\u80da\u80ce\u7814\u7a76\u4e0d\u662f\u4e3a\u4e86\u6297 HIV \u7684\u533b\u5b66\u76ee\u6807\uff0c\u800c\u662f\u4e3a\u4e86\u5f00\u53d1\u4e00\u79cd\u5728\u5355\u7ec6\u80de\u6c34\u5e73\u4e0a\u7cbe\u786e\u5f15\u5165\u4eba\u7c7b\u57fa\u56e0\u7ec4\u53d8\u5316\u7684\u6280\u672f\uff0c\u53ea\u662f\u5f15\u5165\u4e86\u4e00\u4e2a\u5728\u81ea\u7136\u754c\u672c\u6765\u5b58\u5728\u7684\u57fa\u56e0\u53d8\u5316\u3002\u4ed6\u6240\u6307\u7684\u8fd9\u4e2a\u53d8\u5316\uff0c\u662f\u4eba\u7c7b\u4eba\u7fa4\u4e2d\u81ea\u7136\u5b58\u5728\u7684 CCR5 \u57fa\u56e0\u4e2d\u7684 32 \u4e2a\u78b1\u57fa\u5bf9\u7f3a\u5931\u3002<\/span><\/p>\n


<\/p>\n

\u4fc4\u7f57\u65af\u536b\u661f\u901a\u8baf\u793e\u8fd9\u7bc7\u62a5\u9053\u63d0\u5230\uff0c\u5728\u672a\u6765\uff0c\u533b\u5b66\u53ef\u4ee5\u4e3a\u8fd9\u4e9b\u60f3\u8981\u751f\u80b2\u7684\u827e\u6ecb\u75c5\u5973\u6027\u60a3\u8005\u63d0\u4f9b\u4e00\u79cd\u6280\u672f\uff0c\u4f7f\u80ce\u513f\u80fd\u591f\u62b5\u6297 HIV\u3002<\/span><\/p>\n


<\/p>\n

\u7136\u800c\uff0c\u4e0a\u8ff0\u62a5\u9053\u4e2d\u7684\u300c\u672a\u6765\u300d\u6307\u7684\u662f\u534a\u5e74\u540e\u3002Rebrikov \u5df2\u7ecf\u8f6c\u53d8\u7406\u5ff5\uff0c\u51c6\u5907\u5236\u9020\u57fa\u56e0\u7f16\u8f91\u5a74\u513f\u4e86\u3002<\/span><\/strong><\/span>
<\/p>\n


<\/p>\n

 <\/span><\/p>\n


<\/p>\n

\u4fc4\u7f57\u65af\u7684\u76f8\u5173\u89c4\u5219\u5c1a\u4e0d\u660e\u786e<\/strong><\/span><\/p>\n


<\/span><\/p>\n

\u76ee\u524d\uff0cRebrikov \u7684\u5b9e\u9a8c\u80fd\u5426\u987a\u5229\u8fdb\u884c\uff0c\u5c31\u770b\u4fc4\u7f57\u65af\u7684\u6cd5\u5f8b\u662f\u5426\u8bb8\u53ef\u4e86\u3002<\/span>
<\/p>\n


<\/p>\n

\u636e Nature \u62a5\u9053\uff0c\u4fc4\u7f57\u65af\u6cd5\u5f8b\u7981\u6b62\u5728\u5927\u591a\u6570\u60c5\u51b5\u4e0b\u8fdb\u884c\u7684\u57fa\u56e0\u5de5\u7a0b\uff0c\u4f46\u5c1a\u4e0d\u6e05\u695a\u8fd9\u4e9b\u89c4\u5219\u662f\u5426\u4f1a\u5728\u80da\u80ce\u57fa\u56e0\u7f16\u8f91\u65b9\u9762\u5f97\u5230\u5b9e\u65bd\uff0c\u6216\u8005\u5982\u4f55\u5b9e\u65bd\u30022017 \u5e74\uff0c\u4e00\u9879\u9488\u5bf9\u591a\u4e2a\u56fd\u5bb6\u8f85\u52a9\u751f\u6b96\u6cd5\u89c4\u7684\u5206\u6790\u663e\u793a\uff0c\u4fc4\u7f57\u65af\u5173\u4e8e\u8f85\u52a9\u751f\u6b96\u7684\u6cd5\u89c4\u5e76\u6ca1\u6709\u660e\u786e\u63d0\u5230\u57fa\u56e0\u7f16\u8f91\u3002<\/span>
<\/p>\n


<\/p>\n

Rebrikov \u9884\u8ba1\uff0c\u4fc4\u7f57\u65af\u536b\u751f\u90e8\u5c06\u5728\u672a\u6765 9 \u4e2a\u6708\u5185\u660e\u786e\u6709\u5173\u80da\u80ce\u57fa\u56e0\u7f16\u8f91\u4e34\u5e8a\u5e94\u7528\u7684\u89c4\u5b9a\u3002Rebrikov \u8bf4\uff0c\u611f\u67d3 HIV \u7684\u5987\u5973\u8feb\u5207\u9700\u8981\u5e2e\u52a9\uff0c<\/span>\u751a\u81f3\u5728\u4fc4\u7f57\u65af\u51fa\u53f0\u76f8\u5173\u89c4\u5b9a\u4e4b\u524d\uff0c\u4ed6\u5c31\u60f3\u628a\u5b9e\u9a8c\u8fdb\u884c\u4e0b\u53bb\u3002<\/strong><\/span><\/p>\n


<\/p>\n

\u4e3a\u4e86\u51cf\u5c11\u56e0\u5b9e\u9a8c\u800c\u53d7\u5230\u60e9\u7f5a\u7684\u53ef\u80fd\uff0cRebrikov \u8ba1\u5212\u9996\u5148\u5bfb\u6c42\u5305\u62ec\u536b\u751f\u90e8\u5728\u5185\u7684 3 \u4e2a\u653f\u5e9c\u673a\u6784\u7684\u6279\u51c6\u3002\u4ed6\u8bf4\uff0c\u8fd9\u53ef\u80fd\u9700\u8981 1 \u4e2a\u6708\u5230 2 \u5e74\u7684\u65f6\u95f4\u3002<\/span><\/p>\n


<\/p>\n

\"\u8d3a\u5efa\u594e<\/p>\n

Rebrikov \u62c5\u4efb\u526f\u6821\u957f\u7684<\/span><\/p>\n

\u4fc4\u7f57\u65af\u56fd\u7acb\u76ae\u7f57\u6208\u592b\u533b\u79d1\u5927\u5b66<\/span><\/p>\n


<\/p>\n

\u5206\u5b50\u9057\u4f20\u5b66\u5bb6 Konstantin Severinov \u8ba4\u4e3a\uff0c\u83b7\u53d6\u8fd9\u6837\u7684\u6279\u51c6\u53ef\u80fd\u5f88\u96be\uff0c\u56e0\u4e3a\u4fc4\u7f57\u65af\u5f3a\u5927\u7684\u4e1c\u6b63\u6559\u53cd\u5bf9\u57fa\u56e0\u7f16\u8f91\u3002Severinov \u662f\u7f57\u683c\u65af\u5927\u5b66\u7684\u751f\u7269\u5316\u5b66\u4e0e\u5206\u5b50\u751f\u7269\u5b66\u6559\u6388\uff0c\u4ed6\u540c\u65f6\u62c5\u4efb\u65af\u79d1\u5c14\u79d1\u6c83\u79d1\u5b66\u6280\u672f\u7814\u7a76\u9662\u7684\u751f\u547d\u79d1\u5b66\u4e2d\u5fc3\u4e3b\u4efb\uff0c\u4e5f\u662f\u4fc4\u7f57\u65af\u79d1\u5b66\u9662\u5206\u5b50\u9057\u4f20\u5b66\u548c\u57fa\u56e0\u751f\u7269\u5b66\u7814\u7a76\u6240\u7684\u5b9e\u9a8c\u5ba4\u8d1f\u8d23\u4eba\u3002\u6700\u8fd1\u4ed6\u5e2e\u52a9\u4fc4\u7f57\u65af\u653f\u5e9c\u8bbe\u8ba1\u4e86\u4e00\u4e2a\u57fa\u56e0\u7f16\u8f91\u7814\u7a76\u7684\u8d44\u52a9\u9879\u76ee\u3002<\/span><\/p>\n


<\/p>\n

\u8d3a\u5efa\u594e\u4e8b\u4ef6\u53d1\u751f\u540e\uff0c\u5b66\u754c\u4e00\u81f4\u540c\u610f\uff0c\u76ee\u524d\u65e0\u7ea6\u675f\u7684\u5bf9\u4eba\u7c7b\u53ef\u9057\u4f20\u57fa\u56e0\u8fdb\u884c\u7f16\u8f91\u662f\u4e0d\u8d1f\u8d23\u4efb\u7684\u3002\u4e16\u536b\u7ec4\u7ec7\u7684\u4e13\u5bb6\u59d4\u5458\u4f1a\u5c06\u63d0\u4ea4\u7ba1\u7406\u6846\u67b6\uff0c\u5efa\u7acb\u4e00\u4e2a\u900f\u660e\u7684\u5168\u7403\u6ce8\u518c\u767b\u8bb0\u7cfb\u7edf\uff0c\u6536\u5f55\u6240\u6709\u4e0e\u4eba\u7c7b\u57fa\u56e0\u7f16\u8f91\u76f8\u5173\u7684\u7814\u7a76\u9879\u76ee\u3002<\/span><\/p>\n


<\/p>\n

\u4fc4\u7f57\u65af\u5df2\u7ecf\u610f\u8bc6\u5230\u57fa\u56e0\u7f16\u8f91\u7684\u91cd\u8981\u6027\u3002\u4eca\u5e74 4 \u6708\uff0c\u4fc4\u7f57\u65af\u5ba3\u5e03\u63a8\u51fa\u4e00\u9879\u8017\u8d44 1110 \u4ebf\u5362\u5e03\uff0817 \u4ebf\u7f8e\u5143\uff09\u7684\u8054\u90a6\u8ba1\u5212\uff0c\u5e0c\u671b 2020 \u5e74\u524d\u7814\u5236\u51fa 10 \u79cd\u65b0\u7684\u57fa\u56e0\u7f16\u8f91\u4f5c\u7269\u548c\u52a8\u7269\u54c1\u79cd\uff1b\u5230 2027 \u5e74\u518d\u7814\u5236\u51fa\u53e6\u5916 20 \u79cd\u3002<\/span><\/p>\n


<\/p>\n

\u5982\u4eca\uff0cRebrikov \u7684\u7814\u7a76\u8ba1\u5212\u5219\u662f\u4fc4\u7f57\u65af\u533b\u5b66\u9886\u57df\u5728\u57fa\u56e0\u7f16\u8f91\u6280\u672f\u53d1\u5c55\u4e2d\u7b2c\u4e00\u6b21\u4e0a\u5934\u6761\u3002<\/span><\/p>\n


<\/p>\n

 <\/span><\/p>\n


<\/p>\n

\u7ed5\u4e0d\u5f00\u7684\u4f26\u7406\u95ee\u9898<\/strong><\/span><\/p>\n


<\/p>\n

\u4f17\u591a\u79d1\u5b66\u5bb6\u4e0d\u8ba4\u540c\u8d3a\u5efa\u594e\u7684\u7814\u7a76\u3002<\/span><\/p>\n


<\/span><\/p>\n

\u8d3a\u7684\u7814\u7a76\u4e0d\u4ec5\u6ca1\u6709\u4efb\u4f55\u4e34\u5e8a\u4ef7\u503c\uff0c\u6539\u53d8\u80da\u80ce\u57fa\u56e0\u8fd9\u4e2a\u65b9\u6cd5\u4e5f\u4e0d\u662f\u4e00\u4e2a\u6709\u4ef7\u503c\u7684\u5bf9\u6297 HIV \u7684\u4e34\u5e8a\u624b\u6bb5\u2014\u2014<\/span>Rebrikov \u7684\u7814\u7a76\u4ea6\u662f\u5982\u6b64\u3002<\/span><\/p>\n


<\/p>\n

\u57fa\u56e0\u7f16\u8f91\u80da\u80ce\u4e4b\u6240\u4ee5\u4e89\u8bae\u5de8\u5927\uff0c\u5f88\u91cd\u8981\u7684\u4e00\u4e2a\u539f\u56e0\u662f\uff0c\u8fd9\u79cd\u57fa\u56e0\u6539\u53d8\u662f\u80fd\u591f\u8fdb\u5165\u4eba\u7c7b\u57fa\u56e0\u6c60\u7684\u3002\u5982\u679c\u4ed6\u4eec\u957f\u6210\u5a74\u513f\uff0c\u8fd9\u4e9b\u7f16\u8f91\u8fc7\u7684\u57fa\u56e0\u5c31\u53ef\u4ee5\u4f20\u9012\u7ed9\u540e\u4ee3\u3002<\/span><\/strong><\/span><\/p>\n


<\/span><\/p>\n

\u5c3d\u7ba1\u7814\u7a76\u4eba\u5458\u4e00\u81f4\u8ba4\u4e3a\uff0c\u8fd9\u9879\u6280\u672f\u6709\u4e00\u5929\u53ef\u80fd\u6709\u52a9\u4e8e\u6d88\u9664\u9570\u72b6\u7ec6\u80de\u8d2b\u8840\u548c\u56ca\u6027\u7ea4\u7ef4\u5316\u7b49\u9057\u4f20\u75be\u75c5\uff0c\u4f46\u5728\u7528\u4e8e\u4eba\u7c7b\u6539\u9020\u4e4b\u524d\uff0c\u8fd8\u9700\u8981\u8fdb\u884c\u66f4\u591a\u7684\u5b9e\u9a8c\u3002<\/span><\/p>\n


<\/p>\n

\u5bf9\u4e8e Rebrikov \u7684\u7814\u7a76\u8ba1\u5212\uff0c\u79d1\u5b66\u5bb6\u8ba4\u4e3a\u5728\u56fd\u9645\u4f26\u7406\u6846\u67b6\u5c31\u751f\u6001\u548c\u5b89\u5168\u63aa\u65bd\u8fbe\u6210\u4e00\u81f4\u4e4b\u524d\u5e94\u8be5\u7981\u6b62\u6b64\u7c7b\u5b9e\u9a8c\u3002<\/span><\/p>\n


<\/p>\n

\u4f17\u591a\u79d1\u5b66\u5bb6\u548c\u751f\u7269\u4f26\u7406\u5b66\u5bb6\u5bf9 Rebrikov \u7684\u8ba1\u5212\u611f\u5230\u56f0\u60d1\u3002<\/span><\/p>\n


<\/span><\/p>\n

CRISPR-Cas9 \u57fa\u56e0\u7f16\u8f91\u6280\u672f\u7684\u5148\u9a71\u8005\u3001\u52a0\u5dde\u5927\u5b66\u4f2f\u514b\u5229\u5206\u6821\u5206\u5b50\u751f\u7269\u5b66\u5bb6 Jennifer Doudna \u8bf4\uff1a\u300c\u8fd9\u9879\u6280\u672f\u8fd8\u6ca1\u6709\u51c6\u5907\u597d\u3002\u8fd9\u5e76\u4e0d\u4ee4\u4eba\u610f\u5916\uff0c\u4f46\u4ee4\u4eba\u975e\u5e38\u5931\u671b\u548c\u4e0d\u5b89\u3002\u300d<\/span>
<\/p>\n


<\/p>\n

\u5a01\u65af\u5eb7\u661f\u5927\u5b66\u9ea6\u8fea\u900a\u5206\u6821\u7684\u751f\u7269\u4f26\u7406\u548c\u6cd5\u5f8b\u7814\u7a76\u5458 Alta Charo \u8bf4\uff0c\u300cRebrikov \u7684\u8ba1\u5212\u662f\u5bf9\u8fd9\u9879\u6280\u672f\u7684\u975e\u9053\u5fb7\u4f7f\u7528\u3002\u300dCharo \u662f\u4e16\u754c\u536b\u751f\u7ec4\u7ec7\u59d4\u5458\u4f1a\u7684\u6210\u5458\uff0c\u8be5\u59d4\u5458\u4f1a\u6b63\u5728\u4e3a\u4eba\u7c7b\u57fa\u56e0\u7ec4\u7f16\u8f91\u5236\u5b9a\u4f26\u7406\u7ba1\u7406\u653f\u7b56\u3002<\/span><\/p>\n


<\/p>\n

\u54c8\u4f5b\u533b\u5b66\u9662\u9057\u4f20\u5b66\u5bb6 George Daley \u5bf9 Nature \u8868\u793a\uff0c\u4efb\u4f55\u79d1\u5b66\u5bb6\u5728\u8bd5\u56fe\u5c06\u57fa\u56e0\u7f16\u8f91\u80da\u80ce\u690d\u5165\u6bcd\u4f53\u4e4b\u524d\uff0c\u90fd\u9700\u8981\u5c31\u79d1\u5b66\u53ef\u884c\u6027\u548c\u4f26\u7406\u53ef\u63a5\u53d7\u6027\u8fdb\u884c\u900f\u660e\u3001\u516c\u5f00\u7684\u8fa9\u8bba\u3002<\/span><\/p>\n


<\/p>\n

\u5bf9\u8fd9\u7c7b\u7814\u7a76\u4e0d\u8ba4\u540c\u8fd8\u6765\u81ea\u533b\u5b66\u5b9e\u8df5\u3002<\/span><\/strong><\/span><\/p>\n


<\/p>\n

\u8d3a\u5efa\u594e\u7684\u7814\u7a76\u4f7f\u7528\u7684\u662f HIV \u9633\u6027\u7236\u4eb2\u7cbe\u5b50\uff0c\u4ed6\u56e0\u6b64\u5e7f\u53d7\u6279\u8bc4\uff0c\u56e0\u4e3a\u6709\u5f88\u591a\u5176\u4ed6\u65b9\u6cd5\u53ef\u4ee5\u964d\u4f4e\u5a74\u513f HIV \u611f\u67d3\u7684\u98ce\u9669\uff0c\u6765\u9884\u9632 HIV \u7684\u6bcd\u5a74\u4f20\u64ad\uff0c\u57fa\u56e0\u7f16\u8f91\u5a74\u513f\u6070\u6070\u662f\u6700\u4e0d\u6210\u719f\u7684\u89e3\u51b3\u65b9\u6848\u4e4b\u4e00\u3002<\/span><\/p>\n


<\/p>\n

Rebrikov \u5bf9\u6b64\u8868\u793a\u540c\u610f\uff0c\u56e0\u6b64\u4ed6\u8ba1\u5212\u53ea\u5c06\u80da\u80ce\u690d\u5165\u5bf9\u6807\u51c6\u6297\u827e\u6ecb\u75c5\u836f\u7269\u6ca1\u6709\u53cd\u5e94\u7684 HIV \u9633\u6027\u6bcd\u4eb2\u7fa4\u4f53\uff0c\u5979\u4eec\u5c06 HIV \u611f\u67d3\u4f20\u67d3\u7ed9\u5b69\u5b50\u7684\u98ce\u9669\u66f4\u9ad8\u3002Rebrikov \u8bf4\uff0c\u5982\u679c\u57fa\u56e0\u7f16\u8f91\u6210\u529f\u5730\u5931\u6d3b\u4e86 CCR5 \u57fa\u56e0\uff0c\u8fd9\u79cd\u98ce\u9669\u5c06\u5927\u5927\u964d\u4f4e\u3002\u300c\u5728\u8fd9\u6837\u7684\u4e34\u5e8a\u60c5\u51b5\u4e0b\uff0c\u9700\u8981\u8fdb\u884c\u8fd9\u79cd\u57fa\u56e0\u7f16\u8f91\u6cbb\u7597\u3002\u300d<\/span><\/p>\n


<\/p>\n

\u636e Nature \u62a5\u9053\uff0c\u5927\u591a\u6570\u79d1\u5b66\u5bb6\u4ecd\u7136\u8ba4\u4e3a\uff0c\u7f16\u8f91\u80da\u80ce\u4e2d\u7684 CCR5 \u57fa\u56e0\u662f\u6ca1\u6709\u5fc5\u8981\u7684\u3002<\/span><\/strong><\/span><\/p>\n


<\/span><\/strong><\/span><\/p>\n

\u5373\u4f7f\u6cbb\u7597\u6309\u8ba1\u5212\u8fdb\u884c\uff0c\u5e76\u4e14\u7ec6\u80de\u4e2d CCR5 \u57fa\u56e0\u7684\u4e24\u4e2a\u62f7\u8d1d\u90fd\u88ab\u5931\u6d3b\uff0c\u8fd9\u4e9b\u5a74\u513f\u4ecd\u6709\u53ef\u80fd\u611f\u67d3 HIV\uff0c\u56e0\u4e3a CCR5 \u9014\u5f84\u53ea\u662f 90% \u7684 HIV \u611f\u67d3\u7684\u300c\u95e8\u6237\u300d\uff0c\u4f46\u4ecd\u7136\u5b58\u5728\u5176\u4ed6\u611f\u67d3\u9014\u5f84\u3002<\/span><\/strong><\/span><\/p>\n


<\/p>\n

\u6fb3\u5927\u5229\u4e9a\u56fd\u7acb\u5927\u5b66\u7684 Gaetan Burgio \u8bf4\uff0c\u5173\u4e8e\u80da\u80ce\u57fa\u56e0\u7f16\u8f91\u7684\u5b89\u5168\u6027\u4ecd\u6709\u8bb8\u591a\u672a\u77e5\u4e4b\u5904\u3002\u81f3\u4e8e\u7f16\u8f91\u8fd9\u79cd\u57fa\u56e0\u6709\u4ec0\u4e48\u597d\u5904\u5417\uff1f\u4ed6\u76f4\u63a5\u5730\u8868\u793a\u300c\u6211\u6ca1\u770b\u89c1\u3002\u300d<\/span><\/p>\n


<\/p>\n

 <\/span><\/p>\n


<\/p>\n

\u8131\u9776\u95ee\u9898\u771f\u7684\u80fd\u89e3\u51b3\u5417\uff1f<\/strong><\/span><\/p>\n


<\/p>\n

\u4eba\u4eec\u8fd8\u666e\u904d\u62c5\u5fc3\u80da\u80ce\u57fa\u56e0\u7f16\u8f91\u7684<\/span>\u5b89\u5168\u6027\u3002<\/span><\/strong><\/span><\/p>\n


<\/span><\/p>\n

Rebrikov \u58f0\u79f0\u4ed6\u7684\u5b9e\u9a8c\u548c\u8d3a\u5efa\u594e\u4e00\u6837\uff0c\u5c06\u4f7f\u7528 CRISPR-Cas9 \u57fa\u56e0\u7f16\u8f91\u5de5\u5177\uff0c\u5e76\u4e14\u8fd9\u662f\u5b89\u5168\u7684\u3002\u7136\u800c\uff0cCRISPR-Cas9 \u53ef\u80fd\u5bfc\u81f4\u610f\u5916\u7684\u300c\u8131\u9776\u300d\u7a81\u53d8\uff0c\u5373\u9020\u6210\u76ee\u6807\u57fa\u56e0\u4e4b\u5916\u7684\u7a81\u53d8\u3002\u4f8b\u5982\uff0c\u5982\u679c\u5b83\u4eec\u610f\u5916\u300c\u5173\u95ed\u300d\u4e86\u80bf\u7624\u6291\u5236\u57fa\u56e0\uff0c\u5c06\u4f1a\u662f\u5341\u5206\u5371\u9669\u7684\u3002<\/span><\/p>\n


<\/p>\n

\u4f46 Rebrikov \u8bf4\uff0c\u4ed6\u6b63\u5728\u5f00\u53d1\u4e00\u79cd\u6280\u672f\uff0c\u53ef\u4ee5\u786e\u4fdd\u6ca1\u6709\u300c\u8131\u9776\u300d\u7a81\u53d8\uff0c\u4ed6\u8ba1\u5212\u5728\u4e00\u4e2a\u6708\u5185\u5c06\u521d\u6b65\u7814\u7a76\u7ed3\u679c\u53d1\u5e03\u5230\u7f51\u4e0a\uff0c\u53ef\u80fd\u4f1a\u53d1\u5e03\u5728\u9884\u5370\u672c\u7f51\u7ad9 bioRxiv \u6216\u540c\u884c\u8bc4\u5ba1\u671f\u520a\u4e0a\u3002<\/span><\/p>\n


<\/p>\n

Nature \u6742\u5fd7\u91c7\u8bbf\u7684\u79d1\u5b66\u5bb6\u4eec\u5bf9 Rebrikov \u7684\u8bf4\u6cd5<\/span>\u8868\u793a\u6000\u7591\u3002\u8fd9\u6837\u7684\u4fdd\u8bc1\u80fd\u5426\u9488\u5bf9\u9776\u5916\u7a81\u53d8\uff0c\u6216\u53e6\u4e00\u4e2a\u88ab\u79f0\u547c\u4e3a\u300c\u9776\u5185\u7a81\u53d8\u300d\u7684\u5df2\u77e5\u98ce\u9669\uff0c\u5373\u867d\u7136\u76ee\u6807\u57fa\u56e0\u88ab\u7f16\u8f91\uff0c\u5374\u4e0d\u662f\u5b9e\u73b0\u9884\u671f\u7684\u7f16\u8f91\u7ec6\u8282\u3002<\/span><\/p>\n


<\/p>\n

Rebrikov \u53bb\u5e74\u5728\u4fc4\u7f57\u65af\u56fd\u5bb6\u533b\u5b66\u7814\u7a76\u6240\uff08RSMU\uff09\u7b80\u62a5\u4e0a\u53d1\u8868\u7684\u4e00\u7bc7\u8bba\u6587\u4e2d\u6307\u51fa\uff0c\u4ed6\u7684\u6280\u672f\u80fd\u5728\u8d85\u8fc7 50% \u7684\u60c5\u51b5\u4e0b\u6709\u6548\u5931\u6d3b CCR5 \u57fa\u56e0\u7684\u4e24\u4e2a\u62f7\u8d1d\u3002<\/span><\/p>\n


<\/span><\/p>\n

\u503c\u5f97\u6ce8\u610f\u7684\u662f\uff0cRebrikov \u81ea\u5df1\u5c31\u662f\u8fd9\u672c\u671f\u520a\u7684\u4e3b\u7f16\uff0c\u4f46\u4ed6\u8bf4\u4e24\u8005\u4e0d\u5b58\u5728\u5229\u76ca\u51b2\u7a81\uff0c\u56e0\u4e3a\u5ba1\u7a3f\u4eba\u548c\u7f16\u8f91\u5e76\u4e0d\u77e5\u9053\u6587\u7ae0\u4f5c\u8005\u662f\u662f\u8c01\u3002<\/span><\/strong><\/span><\/p>\n


<\/p>\n

\u4f46\u4f5c\u4e3a CRISPR-Cas9 \u57fa\u56e0\u7f16\u8f91\u6280\u672f\u7684\u5148\u9a71\u8005\uff0c\u52a0\u5dde\u5927\u5b66\u4f2f\u514b\u5229\u5206\u6821\u5206\u5b50\u751f\u7269\u5b66\u5bb6 Jennifer Doudna <\/span>\u5bf9\u8fd9\u4e9b\u7ed3\u679c\u8868\u793a\u6000\u7591\uff0c\u300c\u6211\u770b\u5230\u7684\u6570\u636e\u8868\u660e\uff0c\u60f3\u8981\u63a7\u5236 DNA \u4fee\u590d\u7684\u5de5\u4f5c\u65b9\u5f0f\u5e76\u4e0d\u5bb9\u6613\u3002\u300d<\/span><\/p>\n


<\/span><\/p>\n

\u6fb3\u5927\u5229\u4e9a\u56fd\u7acb\u5927\u5b66\u7684 <\/span>Burgio \u4e5f\u8ba4\u4e3a\uff0cCRISPR \u57fa\u56e0\u7f16\u8f91\u53ef\u80fd\u4f1a\u9020\u6210\u5176\u5b83\u96be\u4ee5\u68c0\u6d4b\u7684\u7f3a\u5931\u6216\u63d2\u5165\u3002<\/span>\u9519\u8bef\u7684\u7f16\u8f91\u53ef\u80fd\u610f\u5473\u7740\u57fa\u56e0\u5e76\u6ca1\u6709\u5b8c\u5168\u4e27\u5931\u529f\u80fd\uff0c\u56e0\u6b64\u7ec6\u80de\u4ecd\u7136\u53ef\u4ee5\u88ab HIV \u611f\u67d3\uff0c<\/span><\/strong><\/span>\u6216\u8005\u53d8\u5f02\u7684\u57fa\u56e0\u53ef\u80fd\u4ee5\u5b8c\u5168\u4e0d\u540c\u7684\u3001\u4e0d\u53ef\u9884\u6d4b\u7684\u65b9\u5f0f\u53d1\u6325\u4f5c\u7528\uff0c\u300c\u8fd9\u53ef\u80fd\u662f\u4e00\u4e2a\u771f\u6b63\u7684\u6df7\u4e71\u3002\u300d<\/span><\/p>\n


<\/p>\n

\u66f4\u91cd\u8981\u7684\u662f\uff0c\u5bf9 Rebrikov \u7684\u8ba1\u5212\u6301\u6279\u8bc4\u6001\u5ea6\u7684\u79d1\u5b66\u5bb6\u8868\u793a\uff0c\u672a\u7a81\u53d8\u7684 CCR5 \u6709\u8bb8\u591a\u5c1a\u672a\u88ab\u5145\u5206\u89e3\u91ca\u7684\u529f\u80fd\uff0cCCR5 \u7684\u5b58\u5728\u53ef\u80fd\u63d0\u4f9b\u4e86\u4e00\u4e9b\u597d\u5904\u3002\u4f8b\u5982\uff0c\u5b83\u4f3c\u4e4e\u63d0\u4f9b\u4e86\u4e00\u4e9b\u4fdd\u62a4\uff0c\u4ee5\u5bf9\u6297\u897f\u5c3c\u7f57\u6cb3\u75c5\u6bd2\u6216\u6d41\u611f\u611f\u67d3\u540e\u7684\u4e3b\u8981\u5e76\u53d1\u75c7\u3002<\/span> \u300c<\/span>\u6211\u4eec\u77e5\u9053\u5f88\u591a\u5173\u4e8e CCR5 \u5728 HIV \u8fdb\u5165\u7ec6\u80de\u4e2d\u7684\u4f5c\u7528\uff0c\u4f46\u6211\u4eec\u5bf9\u5b83\u7684\u5176\u4ed6\u5f71\u54cd\u77e5\u4e4b\u751a\u5c11\u3002\u300dBurgio \u8bf4\u3002<\/span><\/p>\n


<\/strong><\/span><\/p>\n

\u6700\u8fd1\u53d1\u8868\u7684\u4e00\u9879 Nature Medicine \u7814\u7a76\u8fd8\u8868\u660e\uff0cCCR5 \u57fa\u56e0\u7684 32 \u4e2a\u78b1\u57fa\u5bf9\u53cc\u7a81\u53d8<\/strong>\u53ef\u80fd\u4f1a\u7f29\u77ed\u5bff\u547d\u3002<\/strong><\/span><\/p>\n


<\/p>\n

Rebrikov \u660e\u767d\uff0c\u5982\u679c\u4ed6\u5728\u4fc4\u7f57\u65af\u7684\u65b0\u89c4\u5b9a\u51fa\u53f0\u4e4b\u524d\u8fdb\u884c\u5b9e\u9a8c\uff0c\u4ed6\u53ef\u80fd\u4f1a\u88ab\u770b\u4f5c\u7b2c\u4e8c\u4e2a\u8d3a\u5efa\u594e\u3002\u4f46\u4ed6\u8868\u793a\uff0c\u53ea\u6709\u786e\u5b9a\u624b\u672f\u7684\u5b89\u5168\u6027\u4ed6\u624d\u4f1a\u8fd9\u4e48\u505a\uff0c\u300c\u6211\u60f3\u6211\u5df2\u7ecf\u75af\u72c2\u5230\u53ef\u4ee5\u8fd9\u4e48\u505a\u4e86\u3002\u300d\u4ed6\u8bf4\u3002<\/span><\/p>\n


<\/p>\n

 <\/span><\/p>\n


<\/p>\n

\u4e13\u8bbf Denis Rebrikov<\/span><\/strong><\/span><\/p>\n


<\/p>\n

Rebrikov \u7a76\u7adf\u4f1a\u600e\u4e48\u505a\uff0c\u4ed6\u7684\u6240\u601d\u6240\u60f3\u662f\u5426\u5df2\u7ecf\u5230\u4e86\u300c\u75af\u72c2\u300d\u7684\u5730\u6b65\uff0c\u6216\u8bb8\u53ea\u6709\u4ed6\u81ea\u5df1\u624d\u77e5\u9053\u3002<\/span>\u6700\u540e\u9644\u4e0a\u5bf9 Rebrikov \u7684\u4e13\u8bbf\uff0c\u6216\u8bb8\u80fd\u591f\u7aa5\u89c1\u4e00\u4e1d\u4ed6\u7684\u60f3\u6cd5\u3002<\/span><\/span><\/p>\n


<\/p>\n

DeepTech\uff1a\u4e0e\u8d3a\u5efa\u594e\u5b9e\u9a8c\u76f8\u6bd4\uff0c\u4f60\u7684\u7814\u7a76\u80fd\u5426\u89e3\u51b3\u8131\u9776\u95ee\u9898\uff1f<\/span><\/p>\n


<\/p>\n

Denis Rebrikov\uff1a\u6211\u4eec\u5efa\u7acb\u4e86\u4e00\u4e2a\u6a21\u578b\uff0c\u53ef\u4ee5\u901a\u8fc7\u5bf9\u6bd4\u4f9b\u4f53\u80da\u80ce\u548c\u7f16\u8f91\u540e\u80da\u80ce\u7684\u57fa\u56e0\u7ec4\u6765\u51c6\u786e\u8bc4\u4f30 CRISPR-Cas9 \u7cfb\u7edf\u7684\u8131\u9776\u884c\u4e3a\u3002<\/span>\u5f53\u7136\uff0c\u6211\u4eec\u4ecd\u7136\u4f1a\u9762\u4e34\u9576\u5d4c\u6548\u5e94\uff0c\u4f46\u8fd9\u662f\u8fc4\u4eca\u4e3a\u6b62\u6700\u63a5\u8fd1\u6b63\u786e\u4e34\u5e8a\u8bd5\u9a8c\u7684\u6a21\u578b\u4e86\u3002<\/span><\/p>\n


<\/span><\/p>\n

\uff08DeepTech \u6ce8\uff1a\u540c\u4e00\u4e2a\u80da\u80ce\u4e2d\uff0c\u6709\u7684\u80da\u80ce\u7ec6\u80de\u7684\u7f16\u8f91\u6210\u529f\uff0c\u6709\u7684\u80da\u80ce\u7ec6\u80de\u6ca1\u6709\u88ab\u7f16\u8f91\uff0c\u8fd9\u6837\u5c31\u5bfc\u81f4\u4e86\u4eba\u4f53\u5b58\u5728\u6ca1\u7f16\u8f91\u7684\u7ec6\u80de\u548c\u7f16\u8f91\u8fc7\u7684\u7ec6\u80de\uff0c\u6210\u4e3a\u5d4c\u5408\u4f53\u3002\uff09<\/span><\/p>\n


<\/p>\n

DeepTech\uff1a\u5f88\u591a\u4eba\u8ba4\u4e3a\u8d3a\u5efa\u594e\u5bf9 CCR5 \u57fa\u56e0\u7684\u7f16\u8f91\u4e0d\u662f\u5fc5\u8981\u7684\uff0c\u56e0\u4e3a\u8fd8\u6709\u5176\u4ed6\u66f4\u597d\u7684\u9009\u62e9\u65b9\u6848\uff0c\u4f60\u5982\u4f55\u770b\u5f85\u8fd9\u4e9b\u610f\u89c1\uff1f<\/span><\/p>\n


<\/p>\n

Denis Rebrikov\uff1a\u53ea\u6709 HIV \u611f\u67d3\u98ce\u9669\u9ad8\u4e8e\u5e73\u5747\u6c34\u5e73\uff0c\u624d\u80fd\u8ba4\u4e3a\u5bf9 CCR5 \u57fa\u56e0\u8fdb\u884c\u7f16\u8f91\u662f\u5408\u7406\u7684\u3002\u4e00\u4e9b\u5973\u6027\u827e\u6ecb\u75c5\u60a3\u8005\u5bf9\u6807\u51c6\u6cbb\u7597\u6ca1\u6709\u53cd\u5e94\uff0c\u90a3\u4e48\u5979\u4eec\u5c31\u662f\u6700\u4f73\u7684\u5b9e\u9a8c\u5bf9\u8c61\u3002<\/span><\/p>\n


<\/p>\n

DeepTech\uff1a\u4fc4\u7f57\u65af\u6cd5\u5f8b\u5728\u8fd9\u65b9\u9762\u9700\u8981\u6539\u8fdb\u5417\uff1f\u5b83\u5e94\u8be5\u5982\u4f55\u6539\u8fdb\uff1f<\/span><\/p>\n


<\/p>\n

Denis Rebrikov\uff1a\u6709\u5fc5\u8981\u5b8c\u5584\u4eba\u7c7b\u9057\u4f20\u5b66\u7684\u89c4\u5219\u548c\u4f53\u7cfb\uff0c\u4ee5\u907f\u514d\u5bf9\u57fa\u56e0\u7ec4\u7f16\u8f91\u7684\u5408\u7406\u5f00\u53d1\u4ea7\u751f\u9650\u5236\u3002<\/span>\uff08\u8d23\u4efb\u7f16\u8f91\uff1a\u5218\u6631<\/span>\uff09<\/span><\/p>\n


<\/p>\n

 <\/span><\/p>\n

\n
\n
\n

\u4f60\u600e\u4e48\u770b\u5f85 Denis Rebrikov \u7684\u7814\u7a76\uff1f<\/span><\/p>\n

\u8fd9\u7a76\u7adf\u662f\u9020\u798f\u4eba\u7c7b\uff0c\u8fd8\u662f\u6f58\u591a\u62c9\u9b54\u76d2\uff1f<\/span><\/p>\n<\/section>\n


<\/section>\n<\/section>\n<\/section>\n

<\/span>
<\/p>\n


<\/span><\/p>\n

\u672c\u6587\u9996\u53d1\u4e8e\u5fae\u4fe1\u516c\u4f17\u53f7 DeepTech\u6df1\u79d1\u6280\uff08ID\uff1adeeptechchina\uff09\u6388\u6743\u4fee\u6539\u53d1\u5e03<\/span>
<\/p>\n


<\/span><\/p>\n

\"\u8d3a\u5efa\u594e<\/span><\/p>\n


<\/p>\n

\u9898\u56fe\u6765\u6e90\uff1aNature<\/span><\/p>\n

\u53c2\u8003\u6765\u6e90\uff1a<\/span><\/p>\n

1.https:\/\/www.nature.com\/articles\/d41586-019-01770-x<\/span><\/p>\n

2.http:\/\/www.pravdareport.com\/science\/141893-hiv\/<\/span><\/p>\n<\/p><\/div>\n","protected":false},"excerpt":{"rendered":"

6 \u6708 10 \u65e5\uff0c\u636e Nature \u62a5\u9053\uff0c\u4fc4\u7f57\u65af\u79d1\u5b66\u5bb6 Denis Rebrikov \u8868\u793a\u4ed6\u8ba1\u5212\u5236\u9020\u66f4\u591a\u57fa\u56e0\u7f16 […]<\/p>\n","protected":false},"author":1,"featured_media":117703,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[2],"tags":[],"_links":{"self":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/117702"}],"collection":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/comments?post=117702"}],"version-history":[{"count":1,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/117702\/revisions"}],"predecessor-version":[{"id":117708,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/117702\/revisions\/117708"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/media\/117703"}],"wp:attachment":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/media?parent=117702"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/categories?post=117702"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/tags?post=117702"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}