{"id":118945,"date":"2019-07-08T11:50:50","date_gmt":"2020-04-20T10:03:30","guid":{"rendered":"http:\/\/www.05921.net\/index.php\/118945\/"},"modified":"2020-04-20T18:03:35","modified_gmt":"2020-04-20T10:03:35","slug":"7788fe16a3","status":"publish","type":"post","link":"https:\/\/www.05921.net\/index.php\/118945\/","title":{"rendered":"ESPGHAN \u5b66\u672f\u4f1a\u8bae\u64ad\u62a5\uff0c4,500 \u540d\u5927\u5496\u89c1\u9762\u804a\u4ec0\u4e48\uff1f"},"content":{"rendered":"
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6 \u6708 8 \u65e5\uff0c\u7b2c 52 \u5c4a\u6b27\u6d32\u513f\u79d1\u80c3\u80a0\u75c5\u5b66\u3001\u809d\u75c5\u5b66\u548c\u8425\u517b\u5b66\u534f\u4f1a\uff08ESPGHAN\uff09\u4f1a\u8bae\u5728\u683c\u62c9\u65af\u54e5\u5706\u6ee1\u843d\u4e0b\u5e37\u5e55\u3002ESPGHAN \u5e74\u4f1a\u662f\u5168\u7403\u513f\u79d1\u80c3\u80a0\u75c5\u5b66\u3001\u809d\u75c5\u5b66\u548c\u8425\u517b\u5b66\u9886\u57df\u7684\u9876\u7ea7\u5b66\u672f\u76db\u4f1a\u3002\u4f5c\u4e3a\u76ee\u524d\u56fd\u9645\u4e0a\u6700\u6743\u5a01\u3001\u6700\u5177\u5e7f\u6cdb\u5f71\u54cd\u529b\u7684\u513f\u79d1\u533b\u5b66\u7ec4\u7ec7\uff0cESPGHAN \u4eca\u5e74\u8fd9\u573a\u5e74\u4f1a\u6c47\u805a\u4e86\u6765\u81ea 90 \u591a\u4e2a\u56fd\u5bb6\u7684 4,500 \u540d\u4e13\u5bb6\u5b66\u8005\uff0c\u4e13\u5bb6\u4eec\u5171\u540c\u7814\u8ba8\u4e86\u513f\u79d1\u9886\u57df\u7684\u6700\u65b0\u7814\u7a76\u70ed\u70b9\uff0c\u5e76\u5206\u4eab\u4e86\u5305\u62ec\u80a0\u9053\u5fae\u751f\u6001\u3001\u5a74\u513f\u8425\u517b\u5065\u5eb7\u3001\u6bcd\u4e73\u7814\u7a76\u7b49\u9886\u57df\u7684\u79d1\u7814\u6210\u679c\u3002<\/p>\n


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\"ESPGHAN<\/p>\n

\u56fe 1 \u7b2c 52 \u5c4a\u6b27\u6d32\u513f\u79d1\u80c3\u80a0\u75c5\u5b66\u3001\u809d\u75c5\u5b66\u548c\u8425\u517b\u5b66\u534f\u4f1a\uff08ESPGHAN\uff09\u4f1a\u8bae<\/span><\/p>\n


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\u5927\u5496\u4e13\u5bb6\u9f50\u4ea4\u6d41\uff0c\u805a\u7126\u5a74\u513f\u80a0\u9053\u5fae\u751f\u6001\u7814\u7a76<\/span><\/strong><\/p>\n


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\u5728\u672c\u5c4a ESPGHAN \u5927\u4f1a\u4e0a\uff0c\u80a0\u9053\u5fae\u751f\u6001\u662f\u70ed\u70b9\u8bae\u9898\u4e4b\u4e00\u3002\u4f17\u6240\u5468\u77e5\uff0c\u80a0\u9053\u5fae\u751f\u6001\u662f\u4eba\u4f53\u5fae\u751f\u6001\u7cfb\u7edf\u7684\u91cd\u8981\u7ec4\u6210\u90e8\u5206\u4e4b\u4e00\uff0c\u80a0\u9053\u5fae\u751f\u6001\u8f85\u52a9\u4eba\u4f53\u8fdb\u884c\u8425\u517b\u7269\u8d28\u7684\u8f6c\u5316\u4e0e\u5438\u6536\u5e76\u4e0e\u591a\u4e2a\u7ec4\u7ec7\u3001\u5668\u5b98\u5b58\u5728\u5bc6\u5207\u7684\u76f8\u4e92\u4f5c\u7528\uff0c\u662f\u4eba\u4f53\u5065\u5eb7\u7684\u91cd\u8981\u4fdd\u969c\u3002<\/p>\n


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\u6ce2\u58eb\u987f\u513f\u7ae5\u533b\u9662\u80c3\u80a0\u75c5\u548c\u8425\u517b\u533b\u751f\u3001\u54c8\u4f5b\u5927\u5b66\u533b\u5b66\u9662 Jon Vanderhoof \u6559\u6388\u5c31\u8fd9\u4e00\u8bae\u9898\u53d1\u8868\u4e86\u5b66\u672f\u6f14\u8bb2\u3002\u4ed6\u8868\u793a\uff0c\u80a0\u9053\u5fae\u751f\u6001\u5bf9\u5065\u5eb7\u81f3\u5173\u91cd\u8981<\/strong><\/span>\uff0c<\/strong>\u4eba\u4f53\u80a0\u9053\u5fae\u751f\u7269\u83cc\u7fa4\u7684\u6539\u53d8\uff0c\u6709\u53ef\u80fd\u5bfc\u81f4\u6211\u4eec\u66f4\u5bb9\u6613\u8fc7\u654f\u6216\u8005\u60a3\u4e0a\u514d\u75ab\u6027\u75be\u75c5\u3002\u4e3a\u964d\u4f4e\u7f79\u60a3\u6b64\u7c7b\u75be\u75c5\u7684\u98ce\u9669\uff0c<\/span>\u53ef\u4ee5\u5bf9\u83cc\u7fa4\u8fdb\u884c\u5e72\u9884\u4ee5\u51cf\u5c11\u75be\u75c5\u60a3\u75c5\u98ce\u9669\uff0c\u800c\u6700\u597d\u7684\u5e72\u9884\u65f6\u673a\u662f\u5728\u751f\u547d\u65e9\u671f<\/strong><\/span> <\/span>[1][2]<\/sup>\u3002<\/p>\n


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\"ESPGHAN<\/p>\n


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\"ESPGHAN<\/p>\n

\u56fe 2 Jon Vanderhoof \u6559\u6388\uff0c\u6ce2\u58eb\u987f\u513f\u7ae5\u533b\u9662\u80c3\u80a0\u75c5\u548c\u8425\u517b\u533b\u751f\u3001\u54c8\u4f5b\u5927\u5b66\u533b\u5b66\u9662\u9ad8\u7ea7\u8bb2\u5e08\uff0c\u62a5\u544a\u9898\u76ee\uff1a\u300aDisorders Impacted By the Gut Microbiome Opportunities for Microbiome Manipulation\u300b<\/span>
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\u4e00\u76f4\u4ee5\u6765\uff0c\u76ca\u751f\u83cc\u4f5c\u4e3a\u6709\u76ca\u83cc\u7684\u4e00\u79cd\uff0c\u5728\u5e2e\u52a9\u8c03\u8282\u80a0\u9053\u83cc\u7fa4\u5e73\u8861\uff0c\u6539\u5584\u5a74\u5e7c\u513f\u80a0\u9053\u73af\u5883\u65b9\u9762\u5df2\u6709\u8bb8\u591a\u63a2\u7d22\u548c\u5b9e\u8df5\u3002\u5728\u6b64\u6b21\u5927\u4f1a\u4e0a\uff0c\u9664\u4e86 Vanderhoof \u6559\u6388\u5916\uff0c\u8fd8\u6709\u5b66\u8005\u5206\u4eab\u4e86\u5173\u4e8e\u76ca\u751f\u83cc\u5bf9\u574f\u6b7b\u6027\u5c0f\u80a0\u7ed3\u80a0\u708e\u7684\u9884\u9632\u8d77\u5230\u6709\u6548\u4f5c\u7528\u7684\u6700\u65b0\u7814\u7a76\u6210\u679c\u3002\u52a0\u4e4b\u76ee\u524d\u76ca\u751f\u83cc\u7528\u4e8e\u5e7c\u513f\u75c5\u6bd2\u6027\u8179\u6cfb\u548c\u6297\u751f\u7d20\u6027\u8179\u6cfb\u5df2\u7ecf\u6709\u4e86\u8f83\u4e3a\u786e\u51ff\u7684\u4e34\u5e8a\u4f9d\u636e\uff0c\u7531\u6b64\u770b\u51fa\uff0c\u76ca\u751f\u83cc\u5bf9\u4eba\u4f53\u5065\u5eb7\u7684\u5f71\u54cd\u662f\u591a\u7ef4\u5ea6\u3001\u52a8\u6001\u3001\u590d\u6742\u4e14\u5e7f\u6cdb\u7684\u3002<\/p>\n


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\"ESPGHAN<\/p>\n

\u56fe\u7247\u6765\u6e90\uff1a\u7ad9\u9177\u6d77\u6d1b<\/span><\/p>\n


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\u52a9\u653b\u514d\u75ab\u7cfb\u7edf\u300c\u72e0\u300d\u89d2\u8272\uff0cHMO \u6210\u5927\u4f1a\u7126\u70b9<\/span><\/strong><\/p>\n


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\u9664\u4e86\u76ca\u751f\u83cc\uff0c\u4e0e\u5a74\u5e7c\u513f\u80a0\u9053\u5fae\u751f\u6001\u5065\u5eb7\u7d27\u5bc6\u76f8\u5173\u7684\u8fd8\u6709\u53e6\u4e00\u4e2a\u91cd\u8981\u89d2\u8272\u2014\u2014\u6bcd\u4e73\u4f4e\u805a\u7cd6\uff08HMO\uff09\u3002HMO \u662f\u6bcd\u4e73\u4e2d\u7b2c\u4e09\u5927\u56fa\u4f53\u6210\u5206\uff0c\u542b\u91cf\u4ec5\u6b21\u4e8e\u4e73\u7cd6\u548c\u8102\u80aa\u3002<\/p>\n


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\u672c\u6b21\u5927\u4f1a\u4e0a\uff0c\u8425\u517b\u5b66\u754c\u5bf9 HMO \u7684\u5173\u6ce8\u4f9d\u65e7\u9ad8\u70e7\u4e0d\u9000\u3002<\/strong>\u6765\u81ea\u7f8e\u56fd\u52a0\u5dde\u5927\u5b66\u5723\u5730\u4e9a\u54e5\u5206\u6821\u513f\u79d1\u6559\u6388 Lars Bode \u535a\u58eb\u8868\u793a\uff0cHMO \u4e0e\u5a74\u513f\u7684\u5065\u5eb7\u72b6\u6001\u7d27\u5bc6\u76f8\u5173<\/span>\uff0c<\/strong>\u6bcd\u4e73\u4f4e\u805a\u7cd6\u53ef\u4f5c\u4e3a\u76ca\u751f\u5143\u5f71\u54cd\u80a0\u9053\u5fae\u751f\u7269\u7fa4\u7684\u7ec4\u6210\uff0c\u4ea6\u53ef\u4ee5\u5145\u5f53\u6297\u9ecf\u9644\u5242\u6216\u53d7\u4f53\u8bf1\u9975\u963b\u6b62\u75c5\u6bd2\u3001\u7ec6\u83cc\u7b49\u75c5\u539f\u4f53\u4e0e\u4e0a\u76ae\u7ec6\u80de\u8868\u9762\u7684\u7cd6\u7ed3\u5408 <\/span>[3][4]<\/sup>\u3002<\/p>\n


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<< \u6ed1\u52a8\u67e5\u770b\u4e0b\u4e00\u5f20\u56fe\u7247  >><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

\u56fe 3 Lars Bode \u6559\u6388\uff0c\u7f8e\u56fd\u52a0\u5dde\u5927\u5b66\u5723\u5730\u4e9a\u54e5\u5206\u6821\u513f\u79d1\u6559\u6388\uff0c\u62a5\u544a\u9898\u76ee\uff1a\u300aHuman Milk Oligosaccharides as primers for the microbiome and immune system\u300b<\/span><\/p>\n


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\u9664\u4e86\u8c03\u8282\u80a0\u9053\u5fae\u751f\u6001\u4e4b\u5916\uff0cHMO \u5bf9\u5a74\u513f\u81ea\u8eab\u514d\u75ab\u7cfb\u7edf\u7684\u5efa\u7acb\u4e5f\u8d77\u5230\u4e86\u76f8\u5f53\u91cd\u8981\u7684\u4f5c\u7528\u3002Lars Bode \u8868\u793a\uff0cHMO \u80fd\u76f4\u63a5\u8c03\u8282\u514d\u75ab\u7ec6\u80de\u7684\u76f8\u4e92\u4f5c\u7528\u548c\u53cd\u5e94\uff0c\u4e0d\u4ec5\u4ec5\u5728\u80a0\u9053\u4e2d\uff0c\u5728\u5faa\u73af\u7cfb\u7edf\u548c\u5176\u4ed6\u7ec4\u7ec7\u4e2d\u4e5f\u6709\u540c\u6837\u7684\u4f5c\u7528\u3002\u76f8\u5173\u7814\u7a76\u8868\u660e\uff0c\u6bcd\u4e73\u4e2d\u7684\u8425\u517b\u6210\u5206\u53ef\u9884\u9632\u8fc7\u654f\u75c7\u72b6\u7684\u53d1\u5c55\uff0c\u5176\u4e2d HMO \u53ef\u80fd\u62c5\u4efb\u4e86\u5f88\u91cd\u8981\u7684\u89d2\u8272\u3002HMO \u53ef\u4ee5\u4fc3\u8fdb\u6709\u76ca\u83cc\u7684\u751f\u957f\u548c\u77ed\u94fe\u8102\u80aa\u9178\u7684\u4ea7\u751f\uff0c\u4ece\u800c\u6709\u5229\u4e8e\u80a0\u9053\u5065\u5eb7\u548c\u5bbf\u4e3b\u7684\u514d\u75ab\u529b<\/strong><\/span> <\/span>[5][6]<\/sup>\u3002<\/strong><\/p>\n


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\"ESPGHAN<\/p>\n

\u56fe 4 HMO \u53ef\u4ee5\u4fc3\u8fdb\u6709\u76ca\u83cc\u7684\u751f\u957f\u548c\u77ed\u94fe\u8102\u80aa\u9178\u7684\u4ea7\u751f\uff0c\u4ece\u800c\u6709\u5229\u4e8e\u80a0\u9053\u5065\u5eb7\u548c\u5bbf\u4e3b\u7684\u514d\u75ab\u529b<\/span><\/p>\n


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\u8b6c\u5982\u6709\u5b66\u8005\u89c2\u5bdf\u5230\uff0c\u6bcd\u4e73\u4e2d 2-\u5ca9\u85fb\u7cd6\u57fa\u5316\u4e73\u7cd6\u6c34\u5e73\u4e0e\u8fc7\u654f\u6027\u75be\u75c5\uff0c\u5982\u6e7f\u75b9\u3001IgE \u76f8\u5173\u6027\u8fc7\u654f\u6709\u7740\u663e\u8457\u76f8\u5173\u6027\u30022-\u5ca9\u85fb\u7cd6\u57fa\u5316\u4e73\u7cd6\u6c34\u5e73\u8f83\u9ad8\u65f6\uff0c\u4e0a\u8ff0\u8fc7\u654f\u6027\u75be\u75c5\u53d1\u751f\u98ce\u9669\u8f83\u4f4e\u3002\u6709\u7814\u7a76\u8005\u8fd8\u63d0\u51fa\uff0c\u5b58\u5728\u4e8e\u4e73\u7cd6-N-\u5ca9\u85fb\u4e94\u7cd6 III\uff08LNFP III\uff09\u4e2d\u7684 LewisX \u6297\u539f\u53ef\u80fd\u4ecb\u5bfc HMOs \u4e0e\u6811\u7a81\u72b6\u7ec6\u80de\u7279\u5f02\u6027 ICAM-3 \u523a\u6fc0\u975e\u6574\u5408\u7d20\u7ed3\u5408\uff0c\u4ece\u800c\u8c03\u8282\u5a74\u5e7c\u513f\u5bf9\u98df\u7269\u7684\u8010\u53d7\u6027\u3002\u8f83\u9ad8\u6d53\u5ea6\u7684 LNFP III \u53ef\u4ee5\u51cf\u8f7b\u725b\u5976\u8fc7\u654f <\/span>[7]<\/sup>\u3002<\/p>\n


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\"ESPGHAN<\/p>\n

\u56fe 5 \u6bcd\u4e73\u4e2d 2-\u5ca9\u85fb\u7cd6\u57fa\u5316\u4e73\u7cd6\u6c34\u5e73\u4e0e\u8fc7\u654f\u6027\u75be\u75c5\uff0c\u5982\u6e7f\u75b9\u3001IgE \u76f8\u5173\u6027\u8fc7\u654f\u6709\u7740\u663e\u8457\u76f8\u5173\u6027<\/span><\/p>\n


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\u610f\u5927\u5229\u5df4\u91cc\u5927\u5b66\u513f\u79d1\u5b66\u6559\u6388 Flavia Indrio \u535a\u58eb\u5728\u6f14\u8bb2\u4e2d\u8868\u793a\uff0cHMO \u6709\u52a9\u5a74\u5e7c\u513f\u5065\u5eb7\u53d1\u80b2\u5df2\u6709\u8d8a\u6765\u8d8a\u591a\u8bc1\u636e\u7684\u652f\u6301\uff0c\u901a\u8fc7\u80a0\u9053\u8c03\u8282\u5a74\u513f\u514d\u75ab\u7cfb\u7edf\u662f\u5176\u8f83\u4e3a\u7a81\u51fa\u7684\u4e00\u4e2a\u7279\u5f81<\/span><\/strong> <\/span>[8][9]<\/sup>\u3002<\/p>\n


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<< \u6ed1\u52a8\u67e5\u770b\u4e0b\u4e00\u5f20\u56fe\u7247  >><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

\u56fe 6 Flavia Indrio \u6559\u6388\uff0c\u610f\u5927\u5229\u5df4\u91cc\u5927\u5b66\u513f\u79d1\u5b66\u6559\u6388\uff0c\u62a5\u544a\u9898\u76ee\uff1a\u300aThe exciting potential of prebiotics, postbiotics and HMOs to support the immune system through the gut\u300b<\/span><\/p>\n


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\u6bcd\u4e73\u7814\u7a76\u6301\u7eed\u53d1\u529b\uff0c\u8425\u517b\u5065\u5eb7\u5212\u91cd\u70b9<\/strong><\/span><\/p>\n


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\u6b64\u6b21 ESPGHAN \u5927\u4f1a\u4e0a\u5927\u5496\u4e91\u96c6\uff0c\u66f4\u6709\u5f88\u591a\u4e2d\u56fd\u4e13\u5bb6\u8fdc\u8d74\u6b27\u6d32\u53c2\u52a0\uff0c\u4f8b\u5982\u5408\u751f\u5143\u8425\u517b\u4e0e\u62a4\u7406\u7814\u7a76\u9662\uff08BINC\uff09\u6b64\u6b21\u4fbf\u9080\u8bf7\u4e86\u591a\u540d\u56fd\u5185\u4e13\u5bb6\u4e00\u540c\u53c2\u4f1a\u3002\u4f1a\u8bae\u7ed3\u675f\u540e\uff0c\u8fd9\u6279\u4e13\u5bb6\u4e5f\u5411\u6211\u4eec\u5206\u4eab\u4e86\u4ed6\u4eec\u7684\u53c2\u4f1a\u7b14\u8bb0\u5185\u5bb9\uff0c\u9488\u5bf9\u8fd9\u6b21\u4f1a\u8bae\u4e0a\u5173\u4e8e\u5a74\u513f\u8425\u517b\u5065\u5eb7\u7684\u7814\u7a76\u6210\u679c\uff0c\u4e3a\u6211\u4eec\u5212\u51fa\u4e86\u91cd\u70b9\u3002<\/p>\n


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\u5728\u4f1a\u8bae\u4e0a\uff0c\u82f1\u56fd\u4f26\u6566\u5e1d\u56fd\u7406\u5de5\u5b66\u9662\u540d\u8a89\u9ad8\u7ea7\u8bb2\u5e08 Rosah Meyer \u5206\u4eab\u9053\uff0c\u6bcd\u4e73\u5582\u517b\u6709\u5229\u4e8e\u8fdc\u671f\u6162\u6027\u75be\u75c5\u7684\u9884\u9632\u3002\u6bcd\u4e73\u4e2d\u542b\u6709\u5404\u79cd\u72ec\u7279\u7684\u5b8f\u91cf\u548c\u5fae\u91cf\u8425\u6210\u5206\u548c\u751f\u7269\u6d3b\u6027\u6210\u5206\uff0c\u53ef\u80fd\u4f1a\u5bf9\u5a74\u513f\u5065\u5eb7\u4ea7\u751f\u8fdc\u671f\u5f71\u54cd <\/span>[10]<\/sup>\u3002<\/p>\n


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<< \u6ed1\u52a8\u67e5\u770b\u4e0b\u4e00\u5f20\u56fe\u7247  >><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

\u56fe 7 Rosah Meyer \u6559\u6388\uff0c\u82f1\u56fd\u4f26\u6566\u5e1d\u56fd\u7406\u5de5\u5b66\u9662\u540d\u8a89\u9ad8\u7ea7\u8bb2\u5e08\uff0c\u62a5\u544a\u9898\u76ee\uff1a\u300aThe Role of early childhood Nutrition on later life\u300b<\/span><\/p>\n


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\u5bf9\u5a74\u513f\u514d\u75ab\u529b\u6709\u91cd\u8981\u5f71\u54cd\u7684\u6bcd\u4e73\u6210\u5206\u4e0d\u6b62\u4e8e\u4e0a\u6587\u63d0\u5230\u7684 HMO\u3002\u5b9e\u9645\u4e0a\uff0c\u6bcd\u4e73\u4e2d\u8fd8\u5929\u7136\u5b58\u5728\u7740\u4e00\u79cd\u540d\u4e3a\u9aa8\u6865\u86cb\u767d\uff08OPN\uff09\u7684\u514d\u75ab\u6fc0\u6d3b\u4e0e\u8c03\u8282\u56e0\u5b50\uff0c\u7814\u7a76\u8868\u660e\uff0c\u8be5\u86cb\u767d\u5728\u5a74\u513f\u514d\u75ab\u7cfb\u7edf\u7684\u53d1\u80b2\u548c\u6210\u719f\u8fc7\u7a0b\u4e2d\u626e\u6f14\u4e86\u91cd\u8981\u89d2\u8272\u3002\u7f8e\u56fd\u4f0a\u5229\u8bfa\u4f0a\u5927\u5b66\u9999\u69df\u5206\u6821\u3001\u52a0\u5dde\u5927\u5b66\u6234\u7ef4\u65af\u5206\u6821\u4e0e\u590d\u65e6\u5927\u5b66\u513f\u79d1\u533b\u9662\u5171\u540c\u5b8c\u6210\u7684\u9aa8\u6865\u86cb\u767d\u5a74\u513f\u4e34\u5e8a\u8bd5\u9a8c\u663e\u793a\uff0c\u8fd9\u79cd\u86cb\u767d\u6709\u52a9\u4e8e\u51cf\u5c11\u4f53\u6e29\u5f02\u5e38\u7684\u53d1\u751f\u98ce\u9669<\/strong><\/span> <\/span>[11]<\/sup>\u3002<\/p>\n


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\u6bcd\u4e73\u662f\u5b9d\u5b9d\u6700\u5929\u7136\u73cd\u8d35\u7684\u8425\u517b\uff0c\u88ab\u516c\u8ba4\u4e3a\u662f\u786e\u4fdd\u513f\u7ae5\u5065\u5eb7\u548c\u751f\u5b58\u7684\u6700\u6709\u6548\u63aa\u65bd\u4e4b\u4e00\u3002\u6570\u636e\u663e\u793a\uff0c\u5982\u679c\u5c06\u6bcd\u4e73\u5582\u517b\u6269\u5927\u5230\u5168\u6c11\uff0c\u6bcf\u5e74\u5c31\u53ef\u633d\u6551\u7ea6 82 \u4e07\u540d\u513f\u7ae5\u7684\u751f\u547d <\/span>[12]<\/sup>\uff0c\u56e0\u6b64\u5bf9\u6bcd\u4e73\u8425\u517b\u7684\u7814\u7a76\u4e00\u76f4\u662f\u8425\u517b\u5b66\u754c\u5e38\u5e74\u7684\u8bfe\u9898\u3002\u7814\u7a76\u8868\u660e\uff0c\u6bcd\u4e73\u4e2d\u7684\u8102\u80aa\u80fd\u591f\u6ee1\u8db3\u5b9d\u5b9d\u751f\u957f\u548c\u80fd\u91cf\u50a8\u5907\u7684\u9700\u8981\uff0c\u5b83\u7684\u91cd\u8981\u6027\u65e0\u53ef\u66ff\u4ee3\u3002<\/p>\n


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\u9700\u8981\u52a0\u4ee5\u91cd\u89c6\u7684\u662f\uff0c\u5c3d\u7ba1\u4e16\u754c\u536b\u751f\u7ec4\u7ec7 \uff08\u7b80\u79f0 WHO\uff09\u63a8\u8350\u6bcd\u4e73\u5582\u517b\u5b9d\u5b9d\u5230 2 \u5c81\u751a\u81f3\u66f4\u957f\u65f6\u95f4\uff0c\u4f46 WHO \u540c\u65f6\u6307\u51fa\u5a74\u513f\u5728\u751f\u547d\u524d\u516d\u4e2a\u6708\u5e94\u5f97\u5230\u7eaf\u6bcd\u4e73\u5582\u517b\uff0c\u4ee5\u5b9e\u73b0\u6700\u4f73\u751f\u957f\u53d1\u80b2\u548c\u5065\u5eb7\u6c34\u51c6\u3002\u4e4b\u540e\uff0c\u5728\u7ee7\u7eed\u6bcd\u4e73\u5582\u517b\u7684\u540c\u65f6\uff0c\u4e3a\u6ee1\u8db3\u5176\u8d8a\u6765\u8d8a\u9ad8\u7684\u8425\u517b\u9700\u6c42\uff0c\u5e94\u7ed9\u5a74\u513f\u63d0\u4f9b\u8425\u517b\u5145\u8db3\u4e14\u5b89\u5168\u7684\u8f85\u98df <\/span>[13]<\/sup>\u3002<\/p>\n


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\"ESPGHAN<\/p>\n

\u56fe\u7247\u6765\u6e90\uff1a\u7ad9\u9177\u6d77\u6d1b<\/span><\/p>\n


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\u5728\u4e2d\u56fd\uff0c\u7531\u4e8e\u4e0d\u5c11\u5988\u5988\u5976\u6c34\u4e0d\u8db3\uff0c\u52a0\u4e4b\u5973\u6027\u52b3\u52a8\u53c2\u4e0e\u5ea6\u8f83\u9ad8\uff0c\u4f7f\u5f97\u5f88\u591a\u5bb6\u5ead\u6bcd\u4e73\u5582\u517b\u96be\u4ee5\u575a\u6301\u5230 2 \u5c81\u3002\u8fd9\u65f6\uff0c\u53ef\u4ee5\u6839\u636e\u533b\u751f\u5efa\u8bae\u4ee5\u53ca\u5b9d\u5b9d\u5065\u5eb7\u53d1\u80b2\u7684\u9700\u6c42\uff0c\u5bfb\u627e\u5408\u9002\u7684\u66ff\u4ee3\u4ea7\u54c1\u3002\u6bd4\u5982\u76ee\u524d\u5e38\u88ab\u8c08\u5230\u7684 SN-2 \u68d5\u6988\u9178\uff0c\u8fd9\u79cd\u68d5\u6988\u9178\u5229\u7528\u4e86\u8102\u80aa\u300c\u6539\u9020\u300d\u6280\u672f\uff0c\u4e0e\u690d\u7269\u6cb9\u4e2d\u7684\u68d5\u6988\u9178\u7ed3\u6784\u4e0d\u540c\u3002\u540e\u8005\u7531\u4e8e\u9971\u548c\u8102\u80aa\u9178\u68d5\u6988\u9178\u5904\u4e8e\u7b2c 1\u30013 \u4f4d\u4e0a\uff0c\u5728\u80a0\u9053\u6c34\u89e3\u540e\u4f1a\u5f62\u6210\u6e38\u79bb\u7684\u68d5\u6988\u9178\u4e0e\u9499\u7ed3\u5408\u6210\u9499\u7682\uff0c\u4ece\u800c\u5f71\u54cd\u9499\u548c\u8102\u80aa\u9178\u7684\u5438\u6536\u3002\u76f8\u53cd\uff0cSN-2 \u68d5\u6988\u9178\u7684\u68d5\u6988\u9178\u4f4d\u4e8e SN-2 \u4f4d\u4e0a\uff0c\u4e0d\u4f1a\u6e38\u79bb\u51fa\u6765\u548c\u9499\u7ed3\u5408\uff0c\u56e0\u6b64\u66f4\u5229\u4e8e\u5a74\u5e7c\u513f\u8425\u517b\u7684\u5438\u6536\u3002\u7814\u7a76\u8868\u660e\uff0cSN-2 \u68d5\u6988\u9178\u80fd\u663e\u8457\u964d\u4f4e\u5a74\u513f\u603b\u7682\u5316\u8102\u80aa\u9178\u6392\u6cc4\u91cf\uff0c\u5373 SN-2 \u68d5\u6988\u9178\u6709\u5229\u4e8e\u5a74\u513f\u5bf9\u8102\u80aa\u9178\u548c\u9499\u7684\u5438\u6536<\/strong><\/span> <\/span><\/strong>[14]<\/sup>\u3002<\/strong><\/p>\n


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\u867d\u7136\u672c\u6b21 ESPGHAN \u5927\u4f1a\u5df2\u843d\u5e55\uff0c\u4f46\u662f\u4e13\u5bb6\u5b66\u8005\u4eec\u7684\u7814\u7a76\u8fd8\u5728\u7ee7\u7eed\u3002\u513f\u79d1\u9886\u57df\u7684\u79d1\u7814\u8fdb\u5c55\u5173\u7cfb\u5168\u7403\u513f\u7ae5\u7684\u5065\u5eb7\uff0c\u672c\u6b21\u53c2\u4f1a\u7684\u5408\u751f\u5143\u4e5f\u5728\u6301\u7eed\u53d1\u529b\uff0c\u5173\u6ce8\u80a0\u9053\u5fae\u751f\u6001\u3001\u6bcd\u4e73\u8425\u517b\u7b49\u591a\u4e2a\u7814\u7a76\u9886\u57df\uff0c\u671f\u5f85\u672a\u6765\u7ed9\u6211\u4eec\u5e26\u6765\u66f4\u591a\u56fd\u9645\u524d\u6cbf\u7684\u79d1\u5b66\u5206\u4eab\u3002<\/p>\n


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\u53c2\u8003\u8d44\u6599\uff1a\uff08\u4e0a\u4e0b\u6ed1\u52a8\u67e5\u770b\uff09<\/span><\/p>\n

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[1] Vanderhoof J, Mitmesser S. Probiotics in the management of children with allergy and other disorders of intestinal inflammation[J]. Beneficial microbes, 2010, 1(4): 351-356.<\/p>\n

[2] Canani R B, Sangwan N, Stefka A T, et al. Lactobacillus rhamnosus GG-supplemented formula expands butyrate-producing bacterial strains in food allergic infants[J]. The ISME journal, 2016, 10(3): 742.<\/p>\n

[3] Strandwitz P, Kim K H, Terekhova D, et al. GABA-modulating bacteria of the human gut microbiota[J]. Nature microbiology, 2019, 4(3): 396.<\/p>\n

[4] Manthey C F, Autran C A, Eckmann L, et al. Human milk oligosaccharides protect against enteropathogenic Escherichia coli attachment in vitro and EPEC colonization in suckling mice[J]. Journal of pediatric gastroenterology and nutrition, 2014, 58(2): 165-168.<\/p>\n

[5] Yu Z T, Chen C, Newburg D S. Utilization of major fucosylated and sialylated human milk oligosaccharides by isolated human gut microbes[J]. Glycobiology, 2013, 23(11): 1281-1292.<\/p>\n

[6] Moritz M L, Ayus J C. Misconceptions and barriers to the use of hypertonic saline to treat hyponatremic encephalopathy[J]. Frontiers in Medicine, 2019, 6: 47.<\/p>\n

[7] Seppo A E , Sc C A A M , Bode L , et al. Human milk oligosaccharides and development of cow\u2019s milk allergy in infants[J]. J Allergy Clin Immunol, 2017, 139(2):708.<\/p>\n

[8] Campeotto F, Suau A, Kapel N, et al. A fermented formula in pre-term infants: clinical tolerance, gut microbiota, down-regulation of faecal calprotectin and up-regulation of faecal secretory IgA[J]. Br J Nutr, 2011, 105(12):1843-1851.<\/p>\n

[9] Granier A, Goulet O, Hoarau C. Fermentation products: immunological effects on human and animal models[J]. Pediatric Research, 2013, 74(2):238-44.<\/p>\n

[10] Indrio F, Martini S, Francavilla R, et al. Epigenetic Matters: The Link between Early Nutrition, Microbiome, and Long-term Health Development[J]. Frontiers in Pediatrics, 2017, 5:178.<\/p>\n

[11] L\u00f6nnerdal, Bo, Kvistgaard A S , Peerson J M , et al. Growth, Nutrition, and Cytokine Response of Breast-fed Infants and Infants Fed Formula With Added Bovine Osteopontin[J]. Journal of Pediatric Gastroenterology and Nutrition, 2016, 62(4):650.<\/p>\n

[12] Victora C G , Bahl R , Barros, Alu\u00edsio J D, et al. Breastfeeding in the 21st century: epidemiology, mechanisms, and lifelong effect[J]. The Lancet, 2016, 387(10017):475-490.<\/p>\n

[13] https:\/\/www.who.int\/features\/factfiles\/breastfeeding\/zh\/<\/p>\n

[14] Bar-Yoseph F , Lifshitz Y , Cohen T , et al. SN2-Palmitate Reduces Fatty Acid Excretion in Chinese Formula-fed Infants[J]. Journal of Pediatric Gastroenterology and Nutrition, 2016, 62.<\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n


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\u8d23\u4efb\u7f16\u8f91\uff1a\u738b\u5a55<\/span><\/p>\n

\u56fe\u7247\u6765\u6e90\uff1a<\/span>\u62cd\u6444\u4e8e\u7b2c 52 \u5c4a ESPGHAN \u73b0\u573a<\/span><\/span><\/p>\n<\/section>\n<\/section><\/div>\n","protected":false},"excerpt":{"rendered":"

6 \u6708 8 \u65e5\uff0c\u7b2c 52 \u5c4a\u6b27\u6d32\u513f\u79d1\u80c3\u80a0\u75c5\u5b66\u3001\u809d\u75c5\u5b66\u548c\u8425\u517b\u5b66\u534f\u4f1a\uff08ESPGHAN\uff09\u4f1a\u8bae\u5728\u683c\u62c9\u65af\u54e5\u5706\u6ee1\u843d\u4e0b\u5e37\u5e55\u3002 […]<\/p>\n","protected":false},"author":1,"featured_media":118946,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[2],"tags":[],"_links":{"self":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/118945"}],"collection":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/comments?post=118945"}],"version-history":[{"count":1,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/118945\/revisions"}],"predecessor-version":[{"id":118961,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/118945\/revisions\/118961"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/media\/118946"}],"wp:attachment":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/media?parent=118945"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/categories?post=118945"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/tags?post=118945"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}