{"id":120968,"date":"2019-11-11T23:15:56","date_gmt":"2020-04-21T00:47:43","guid":{"rendered":"http:\/\/www.05921.net\/index.php\/120968\/"},"modified":"2020-04-21T08:47:44","modified_gmt":"2020-04-21T00:47:44","slug":"d49c53e463","status":"publish","type":"post","link":"https:\/\/www.05921.net\/index.php\/120968\/","title":{"rendered":"\u534e\u9886\u533b\u836fDorzagliatin\u5355\u836f\u6cbb\u7597III\u671f\u6ce8\u518c\u4e34\u5e8a\u7814\u7a76(HMM0301)\u8fbe\u5230\u7814\u7a76\u4e3b\u8981\u7597\u6548\u7ec8\u70b9\uff01"},"content":{"rendered":"<div class=\"bpp-post-content\">\n<p style=\"text-align: center;\"><img class=\"rich_pages\"      style=\"\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2020\/04\/6-1587430064.jpeg\" alt=\"\u534e\u9886\u533b\u836fDorzagliatin\u5355\u836f\u6cbb\u7597III\u671f\u6ce8\u518c\u4e34\u5e8a\u7814\u7a76(HMM0301)\u8fbe\u5230\u7814\u7a76\u4e3b\u8981\u7597\u6548\u7ec8\u70b9\uff01\" title=\"\u534e\u9886\u533b\u836fDorzagliatin\u5355\u836f\u6cbb\u7597III\u671f\u6ce8\u518c\u4e34\u5e8a\u7814\u7a76(HMM0301)\u8fbe\u5230\u7814\u7a76\u4e3b\u8981\u7597\u6548\u7ec8\u70b9\uff01\"  \/><\/p>\n<p><span style=\"color: rgb(12, 12, 12);font-family: \u5fae\u8f6f\u96c5\u9ed1;font-size: 14px;letter-spacing: 0.544px;background-color: rgb(255, 255, 255);\">\u201c\u672c\u6587\u6765\u6e90\u4e8e\u534e\u9886\u533b\u836f\u5fae\u4fe1\u516c\u4f17\u53f7\uff08ID\uff1ahuamedicine )\u201d<\/span><br  \/><\/p>\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;font-size: 14px;color: rgb(89, 89, 89);line-height: 1.75;overflow-wrap: break-word !important;\">\n<section style=\"margin-top: 5px;margin-right: 5px;margin-left: 5px;max-width: 100%;box-sizing: border-box;line-height: 2em;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;color: rgb(12, 12, 12);overflow-wrap: break-word !important;\"><\/p>\n<section style=\"max-width: 100%;box-sizing: border-box;font-size: 16px;overflow-wrap: break-word !important;\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\">\n<section style=\"padding-right: 15px;padding-bottom: 15px;padding-left: 15px;max-width: 100%;box-sizing: border-box;display: inline-block;width: 667px;vertical-align: top;background-color: rgb(200, 233, 255);box-shadow: rgb(0, 0, 0) 0px 0px 0px;overflow-wrap: break-word !important;\">\n<section class=\"\" style=\"margin-bottom: -22px;max-width: 100%;box-sizing: border-box;text-align: left;transform: translate3d(15px, 0px, 0px);overflow-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box;display: inline-block;width: 70px;height: 50px;vertical-align: top;overflow: hidden;overflow-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box;text-align: center;overflow-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box;vertical-align: middle;display: inline-block;line-height: 0;overflow-wrap: break-word !important;\"><img class=\"\"     style=\"box-sizing: border-box;vertical-align: middle;overflow-wrap: break-word !important;width: 311px !important;visibility: visible !important;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2020\/04\/3-1587430064.png\" alt=\"\u534e\u9886\u533b\u836fDorzagliatin\u5355\u836f\u6cbb\u7597III\u671f\u6ce8\u518c\u4e34\u5e8a\u7814\u7a76(HMM0301)\u8fbe\u5230\u7814\u7a76\u4e3b\u8981\u7597\u6548\u7ec8\u70b9\uff01\" title=\"\u534e\u9886\u533b\u836fDorzagliatin\u5355\u836f\u6cbb\u7597III\u671f\u6ce8\u518c\u4e34\u5e8a\u7814\u7a76(HMM0301)\u8fbe\u5230\u7814\u7a76\u4e3b\u8981\u7597\u6548\u7ec8\u70b9\uff01\"  \/><\/section>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\">\n<section style=\"padding: 20px;max-width: 100%;box-sizing: border-box;display: inline-block;width: 637px;vertical-align: top;border-width: 2px;border-radius: 10px;border-style: none;border-color: rgb(0, 112, 192);overflow: hidden;background-image: linear-gradient(225deg, rgb(0, 112, 192) 0%, rgb(0, 160, 255) 100%);overflow-wrap: break-word !important;\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;font-size: 14px;color: rgb(255, 255, 255);line-height: 1.8;letter-spacing: 1.8px;overflow-wrap: break-word !important;\">\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;overflow-wrap: break-word !important;\">Dorzagliatin\u5355\u836f\u6cbb\u7597III\u671f\u6ce8\u518c\u4e34\u5e8a\u7814\u7a76(HMM0301)24\u5468\u6838\u5fc3\u6570\u636e\u7ed3\u679c\uff0c\u8fbe\u5230\u7814\u7a76\u4e3b\u8981\u7597\u6548\u7ec8\u70b9<\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;overflow-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;overflow-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u9996\u6b21\u5f00\u5c55\uff1a<\/strong>\u9488\u5bf92\u578b\u7cd6\u5c3f\u75c5\u75c5\u56e0\u3001\u4e13\u6ce8\u4fee\u590d\u8840\u7cd6\u4f20\u611f\u8461\u8404\u7cd6\u6fc0\u9176\u3001\u91cd\u5851\u8840\u7cd6\u7a33\u6001\u7684III\u671f\u6ce8\u518c\u4e34\u5e8a\u7814\u7a76<\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;overflow-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;overflow-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u5b89\u5168\u548c\u8010\u53d7\u6027\u597d\uff1a<\/strong>dorzagliatin \u6cbb\u759724\u5468\u671f\u95f4\u4f4e\u8840\u7cd6\u53d1\u751f\u7387\u4f4e\u4e8e\u767e\u5206\u4e4b\u4e00,\u65e0\u836f\u7269\u76f8\u5173\u7684\u4e25\u91cd\u4e0d\u826f\u4e8b\u4ef6\u53d1\u751f<\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;overflow-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;overflow-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u7597\u6548\u663e\u8457\uff1a<\/strong>dorzagliatin\u6cbb\u759724\u5468\u540e\u7cd6\u5316\u8840\u7ea2\u86cb\u767d\u76f8\u5bf9\u57fa\u7ebf\u964d\u4f4e1.07%\uff0c\u663e\u8457\u4f18\u4e8e\u5b89\u6170\u5242\uff0cp\u503c\u5c0f\u4e8e0.0001<\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;overflow-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;overflow-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u9996\u6b21\u5b9e\u73b0\uff1a<\/strong>\u7531\u4e2d\u56fd\u521b\u65b0\u751f\u7269\u6280\u672f\u516c\u53f8\u7814\u53d1\u7684\u5168\u7403\u9996\u521b2\u578b\u7cd6\u5c3f\u75c5\u65b0\u836f\u8fbe\u5230\u4e3b\u8981\u7597\u6548\u7ec8\u70b9<\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"\" style=\"margin-top: -1px;margin-bottom: 10px;max-width: 100%;box-sizing: border-box;text-align: center;overflow-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box;vertical-align: middle;display: inline-block;line-height: 0;width: 667px;overflow-wrap: break-word !important;\"><svg class=\"\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" x=\"0px\" y=\"0px\" viewbox=\"0 0 828.5 74.6\" style=\"vertical-align: middle;max-width: 100%;width: 100%;box-sizing: border-box;\" width=\"100%\"><path d=\"M828.5-69.2v97.5c-57.3,7.2-133.9,14.8-203.8,14.8c-133.8,0-280.8-28.5-417.7-28.5C103.4,14.6,29.7,25.2,0,30.3v-99.6H828.5   z\" fill=\"rgb(200,233,255)\" style=\"box-sizing: border-box;\"><\/path><path style=\"box-sizing: border-box;\" d=\"M828.5,28.3V49c-57.3,12.5-133.9,25.6-203.8,25.6c-133.8,0-280.8-49.3-417.7-49.3   C103.4,25.3,29.7,43.6,0,52.5V30.3c29.7-5.2,103.4-15.7,206.9-15.7c136.9,0,283.8,28.5,417.7,28.5C694.6,43.1,771.2,35.5,828.5,28.3   z\" fill=\"rgba(200,233,255,0.52)\"><\/path><\/svg><\/section>\n<\/section>\n<\/section>\n<p><\/span><\/section>\n<p style=\"margin-top: 5px;margin-right: 5px;margin-left: 5px;max-width: 100%;box-sizing: border-box;min-height: 1em;line-height: normal;overflow-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"  \/><\/p>\n<section style=\"margin-top: 5px;margin-right: 5px;margin-left: 5px;max-width: 100%;box-sizing: border-box;line-height: 2em;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;color: rgb(12, 12, 12);overflow-wrap: break-word !important;\">2019\u5e7411\u670812\u65e5, \u4e0a\u6d77 &#8211; \u534e\u9886\u533b\u836f\u4e8e\u4eca\u5929\u516c\u5e03\u5168\u7403\u9996\u521b\u7684\u53cc\u91cd\u673a\u5236\u8461\u8404\u7cd6\u6fc0\u9176\u6fc0\u6d3b\u5242 dorzagliatin (HMS5552) \u7684\u5355\u836f\u6cbb\u7597III\u671f\u4e34\u5e8a\u7814\u7a76 (HMM0301\uff0cNCT03173391) \u768424\u5468\u6838\u5fc3\u7814\u7a76\u7ed3\u679c\u3002<\/span><span style=\"max-width: 100%;color: rgb(12, 12, 12);overflow-wrap: break-word !important;\">Dorzagliatin\u662f\u57fa\u4e8e\u8461\u8404\u7cd6\u6fc0\u9176glucokinase (GK) \u4f5c\u4e3a\u8840\u7cd6\u4f20\u611f\u5668\uff0c\u5728\u8840\u7cd6\u7a33\u6001\u8c03\u63a7\u4e2d\u53d1\u6325\u6838\u5fc3\u4f5c\u7528\u7684\u5168\u7403\u9886\u5148\u79d1\u5b66\u6982\u5ff5\u800c\u5f00\u53d1\u3002<\/span><span style=\"max-width: 100%;color: rgb(12, 12, 12);overflow-wrap: break-word !important;\">\u901a\u8fc7\u4fee\u590d\u6210\u5e742\u578b\u7cd6\u5c3f\u75c5\u60a3\u8005\u4e0b\u964d\u7684GK\u529f\u80fd\uff0c\u91cd\u5851\u8840\u7cd6\u7a33\u6001\uff0c\u800c\u5b9e\u73b0\u6cbb\u75972\u578b\u7cd6\u5c3f\u75c5\u3002<\/span><span style=\"max-width: 100%;color: rgb(12, 12, 12);overflow-wrap: break-word !important;\">\u534e\u9886\u533b\u836f\u5728\u4e2d\u56fd\u540c\u65f6\u5f00\u5c552\u987952\u5468\u7684III\u671f\u6ce8\u518c\u4e34\u5e8a\u7814\u7a76\uff0c\u6b64\u6b21\u516c\u5e03\u7684\u662f\u5728\u4ece\u672a\u63a5\u53d7\u8fc7\u7cd6\u5c3f\u75c5\u836f\u7269\u6cbb\u7597\u76842\u578b\u7cd6\u5c3f\u75c5\u60a3\u8005\u4e2d\u5f00\u5c55\u7684HMM0301\u768424\u5468\u7814\u7a76\u7ed3\u679c\u3002<\/span><span style=\"max-width: 100%;color: rgb(12, 12, 12);overflow-wrap: break-word !important;\">HMM0301\u4e34\u5e8a\u7814\u7a76\u7684\u524d24\u5468\u4e3a\u968f\u673a\u53cc\u76f2\u3001\u5b89\u6170\u5242\u5bf9\u7167\u7684\u7597\u6548\u548c\u5b89\u5168\u6027\u7814\u7a76\uff0c\u60a3\u8005\u4ee52\uff1a<\/span><span style=\"max-width: 100%;color: rgb(12, 12, 12);overflow-wrap: break-word !important;\">1\u6bd4\u4f8b\u7eb3\u5165dorzagliatin\u6216\u5b89\u6170\u5242\u7ec4\uff0c\u63a5\u53d7\u4e00\u5929\u4e24\u6b21dorzagliatin 75mg\u6216\u5b89\u6170\u5242\u6cbb\u7597\uff0c\u7814\u7a76\u8005\u6bcf4\u5468\u8fdb\u884c\u4e00\u6b21\u968f\u8bbf\uff0c\u8be5\u7814\u7a76\u7684\u540e28\u5468\u4e3a\u5f00\u653e\u5f0f\u6d3b\u6027\u836f\u7269\u6cbb\u7597\u7684\u5b89\u5168\u6027\u7814\u7a76\uff0c\u6240\u6709\u60a3\u8005\u5747\u63a5\u53d7dorzagliatin 75mg\u4e00\u5929\u4e24\u6b21\u6cbb\u7597\u3002<\/span><br style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"  \/><\/section>\n<section style=\"margin-right: 5px;margin-left: 5px;max-width: 100%;box-sizing: border-box;line-height: 1.75em;overflow-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"  \/><\/section>\n<p style=\"margin-right: 5px;margin-left: 5px;max-width: 100%;min-height: 1em;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;color: rgb(12, 12, 12);overflow-wrap: break-word !important;\">HMM0301\u4e34\u5e8a\u7814\u7a76\u5df2\u8fbe\u5230\u4e3b\u8981\u7597\u6548\u7ec8\u70b9\u3002\u7ecf\u8fc724\u5468\u6cbb\u7597\uff0cdorzagliatin\u6cbb\u7597\u7ec4\u7684\u7cd6\u5316\u8840\u7ea2\u86cb\u767d(HbA1c)\u4ece\u57fa\u7ebf8.35%\u964d\u4f4e\u4e861.07%(\u6700\u5c0f\u4e8c\u4e58\u6cd5\u5e73\u5747\u503c)\uff0c\u5b89\u6170\u5242\u7ec4\u4ece\u57fa\u7ebf8.37%\u964d\u4f4e\u4e860.5%\u3002dorzagliatin\u6cbb\u7597\u7ec4HbA1c\u964d\u4f4e\u4e0e\u5b89\u6170\u5242\u7ec4\u76f8\u6bd4\uff0c\u7ec4\u95f4\u5dee\u5f02\u5177\u6709\u663e\u8457\u7684\u7edf\u8ba1\u5b66\u610f\u4e49(p &lt; 0.0001)\u3002\u9488\u5bf9\u7b26\u5408\u65b9\u6848\u6570\u636e\u96c6\u7684\u5206\u6790\u7ed3\u679c\u663e\u793a\uff0c\u6309\u7167\u7f8e\u56fd\u7cd6\u5c3f\u75c5\u534f\u4f1aADA\u7684\u6cbb\u7597\u8fbe\u6807\u6807\u51c6(\u6cbb\u7597\u540eHbA1c\u4f4e\u4e8e7%)\uff0cdorzagliatin\u6cbb\u7597\u7ec445.5%\u7684\u60a3\u8005\u8fbe\u6807\uff0c\u5bf9\u6bd4\u5b89\u6170\u5242\u7ec421.5%\u8fbe\u6807\u7387\uff0c\u7ec4\u95f4\u5dee\u5f02\u5177\u6709\u663e\u8457\u7684\u7edf\u8ba1\u5b66\u610f\u4e49(PPS, p&lt; 0.0001)\uff1b\u8840\u7cd6\u7a33\u6001\u63a7\u5236\u7387\u590d\u5408\u7ec8\u70b9\uff0c\u5373HbA1c\u6cbb\u7597\u8fbe\u6807\u4e14\u540c\u65f6\u65e0\u4f4e\u8840\u7cd6\u4e8b\u4ef6\u53d1\u751f\uff0c\u5728dorzagliatin\u7ec4\u8fbe\u523045%\uff0c\u663e\u8457\u9ad8\u4e8e\u5b89\u6170\u5242\u7ec421.5%\u8fbe\u6807\u7387(p&lt; 0.0001)\u3002<\/span><\/p>\n<section style=\"margin-right: 5px;margin-left: 5px;max-width: 100%;box-sizing: border-box;line-height: 1.75em;overflow-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"  \/><\/section>\n<p style=\"margin-right: 5px;margin-left: 5px;max-width: 100%;min-height: 1em;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;color: rgb(12, 12, 12);overflow-wrap: break-word !important;\">Dorzagliatin\u572824\u5468\u5355\u836f\u6cbb\u7597\u671f\u95f4\u5b89\u5168\u8010\u53d7\u6027\u597d\uff0c\u4e0e2018\u5e745\u6708\u53d1\u8868\u5728\u300a\u67f3\u53f6\u5200\uff1a\u7cd6\u5c3f\u75c5\u5185\u5206\u6ccc\u300b\u6742\u5fd7\u4e0a\u7684II\u671f\u4e34\u5e8a\u7814\u7a76\u7ed3\u679c\u4e00\u81f4\u3002\u6309\u7167\u7f8e\u56fd\u7cd6\u5c3f\u75c5\u534f\u4f1aADA\u7684\u4f4e\u8840\u7cd6\u6807\u51c6\uff0c\u4e34\u5e8a\u76f8\u5173\u4f4e\u8840\u7cd6 \u53d1\u751f\u7387\u4f4e\u4e8e1%\uff0c\u4e14\u672a\u89c2\u5bdf\u5230\u4e25\u91cd\u4f4e\u8840\u7cd6 \u3002\u9488\u5bf9\u4e34\u5e8a\u5b89\u5168\u6570\u636e\u96c6\u7684\u5206\u6790\u7ed3\u679c\u663e\u793a\uff0cdorzagliatin\u4e0e\u5b89\u6170\u5242\u7ec4\u53cc\u76f2\u671f\u671f\u95f4\u7684\u4e0d\u826f\u4e8b\u4ef6\u53d1\u751f\u7387\u76f8\u4f3c\uff0c\u5927\u90e8\u5206\u7684\u4e0d\u826f\u4e8b\u4ef6\u4e25\u91cd\u7a0b\u5ea6\u4e3a\u8f7b\u5ea6\uff0c\u65e0\u6b7b\u4ea1\u4e8b\u4ef6\u3002Dorzagliatin\u6cbb\u7597\u7ec4\uff0c\u672a\u53d1\u751f\u7814\u7a76\u8005\u5224\u5b9a\u7684\u4e0e\u836f\u7269\u76f8\u5173\u7684\u4e25\u91cd\u4e0d\u826f\u4e8b\u4ef6\u3002<\/span><\/p>\n<section style=\"margin-right: 5px;margin-left: 5px;max-width: 100%;box-sizing: border-box;line-height: 1.75em;overflow-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"  \/><\/section>\n<p style=\"margin-right: 5px;margin-left: 5px;max-width: 100%;min-height: 1em;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;color: rgb(12, 12, 12);overflow-wrap: break-word 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style=\"margin-right: 5px;margin-left: 5px;max-width: 100%;box-sizing: border-box;line-height: 1.75em;overflow-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"  \/><\/section>\n<p style=\"margin-right: 5px;margin-left: 5px;max-width: 100%;min-height: 1em;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;color: rgb(12, 12, 12);overflow-wrap: break-word !important;\">&#8220;\u6211\u4eec\u5bf9dorzagliatin\u5355\u836f\u4e34\u5e8a\u7814\u7a76\u7ed3\u679c\u975e\u5e38\u5174\u594b\uff0c\u5b83\u9996\u6b21\u5728\u4e34\u5e8a\u8bd5\u9a8c\u4e2d\u9a8c\u8bc1\u4e86\u4f7f\u7528\u53cc\u91cd\u673a\u5236\u8461\u8404\u7cd6\u6fc0\u9176\u6fc0\u6d3b\u5242\u6cbb\u75972\u578b\u7cd6\u5c3f\u75c5\u662f\u53ef\u884c\u7684\u3001\u6709\u6548\u7684\u3001\u5b89\u5168\u7684\u3002&#8221; \u534e\u9886\u533b\u836f\u521b\u59cb\u4eba\uff0c\u9996\u5e2d\u79d1\u5b66\u5b98\uff0c\u9996\u5e2d\u6267\u884c\u5b98\u9648\u529b\u535a\u8bf4\u3002&#8221;\u534e\u9886\u533b\u836f\u4e00\u76f4\u5728\u5f00\u5c55\u5bf9dorzagliatin\u7684\u5404\u9879\u7814\u7a76\uff0c\u65e8\u5728\u901a\u8fc7\u5bf9\u5176\u6700\u4f4e\u6cbb\u7597\u6709\u6548\u5242\u91cf\u7684\u63a2\u7d22\uff0c\u4f7fdorzagliatin\u6210\u4e3a\u4fee\u590d\u8840\u7cd6\u4f20\u611f\u5668GK\u529f\u80fd\u7684\u57fa\u77f3\u836f\u7269\uff0c\u7528\u5355\u836f\uff0c\u6216\u8054\u5408\u4e34\u5e8a\u5e7f\u6cdb\u4f7f\u7528\u7684\u964d\u7cd6\u836f\u54c1\uff0c\u5982\u4e8c\u7532\u53cc\u80cd\uff0cDPP4\u6291\u5236\u5242\uff0cSGLT2\u6291\u5236\u5242\uff0cGLP-1\u53d7\u4f53\u6fc0\u52a8\u5242\u6216\u80f0\u5c9b\u7d20\uff0c\u6765\u5b9e\u73b02\u578b\u7cd6\u5c3f\u75c5\u7684\u4e2a\u6027\u5316\u6cbb\u7597\uff0c\u904f\u5236\u7cd6\u5c3f\u75c5\u7684\u53d1\u751f\u548c\u53d1\u5c55\u3002\u6211\u4eec\u6b63\u5728\u5f00\u5c55\u7684 HMM0302\u3010NCT03141073\u3011III\u671f\u4e34\u5e8a\u8bd5\u9a8c\u5c31\u662f\u5728\u4e8c\u7532\u53cc\u80cd\u8db3\u91cf\u6cbb\u7597\u5931\u6548\u76842\u578b\u7cd6\u5c3f\u75c5\u60a3\u8005\u4e2d\u5c55\u5f00\u7684\uff0c\u5e0c\u671bdorzagliatin\u8054\u5408\u4e8c\u7532\u53cc\u80cd\u80fd\u7ed9\u6b64\u7c7b\u60a3\u8005\u5e26\u6765\u798f\u97f3\u3002\u6211\u4eec\u6b63\u5728\u7f8e\u56fd\u548c\u4e2d\u56fd\u5f00\u5c55\u7740\u591a\u4e2a\u4e34\u5e8a\u7814\u7a76\uff0c\u63a2\u7d22dorzagliatin\u5728\u4e0d\u540c\u76842\u578b\u7cd6\u5c3f\u75c5\u60a3\u8005\u4eba\u7fa4\u6cbb\u7597\u6548\u679c\uff0c\u4ee5\u53ca\u5728\u4ee3\u8c22\u6027\u75be\u75c5\u548c\u8ba4\u77e5\u529f\u80fd\u969c\u788d\u76f8\u5173\u9886\u57df\u7684\u65b0\u7528\u9014\u3002\u201d<\/span><\/p>\n<section style=\"margin-right: 5px;margin-left: 5px;max-width: 100%;box-sizing: border-box;line-height: 1.75em;overflow-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"  \/><\/section>\n<p style=\"margin-right: 5px;margin-left: 5px;max-width: 100%;min-height: 1em;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;color: rgb(12, 12, 12);overflow-wrap: break-word !important;\">HMM0302\u7814\u7a76\u7684\u9996\u5e2d\u7814\u7a76\u8005\u3001\u4e2d\u534e\u533b\u5b66\u4f1a\u7cd6\u5c3f\u75c5\u5b66\u5206\u4f1a\u524d\u4e3b\u4efb\u59d4\u5458\u3001\u4e2d\u65e5\u53cb\u597d\u533b\u9662\u5185\u5206\u6ccc\u79d1\u4ee3\u8c22\u4e2d\u5fc3\u524d\u4e3b\u4efb\u6768\u6587\u82f1\u6559\u6388\uff1a\u201c\u8fd9\u4e00\u91cc\u7a0b\u7891\uff0c\u65e0\u8bba\u5bf9\u4e2d\u56fd\u7cd6\u5c3f\u75c5\u836f\u54c1\u5e02\u573a\uff0c\u8fd8\u662f\u5168\u7403\u7cd6\u5c3f\u75c5\u60a3\u8005\uff0c\u90fd\u5177\u6709\u91cd\u5927\u610f\u4e49\u3002\u9664\u4e86\u8fd9\u4e2a\u91cd\u8981\u7684III\u671f\u4e34\u5e8a\u7814\u7a76\uff0c\u76ee\u524d\u8fd8\u6709\u591a\u9879dorzagliatin\u7684\u4e34\u5e8a\u7814\u7a76\u5728\u4e2d\u56fd\u8fdb\u884c\u3002\u6211\u4eec\u76f8\u4fe1dorzagliatin\u4e3a\u89e3\u51b32\u578b\u7cd6\u5c3f\u75c5\u7684\u75c5\u56e0\u63d0\u4f9b\u4e86\u65b0\u7684\u5e0c\u671b\u3002\u201d<\/span><\/p>\n<section style=\"margin-right: 5px;margin-left: 5px;max-width: 100%;box-sizing: border-box;line-height: 1.75em;overflow-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"  \/><\/section>\n<p style=\"margin-right: 5px;margin-left: 5px;max-width: 100%;min-height: 1em;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;color: rgb(12, 12, 12);overflow-wrap: break-word !important;\">&#8220;\u6211\u4eec\u5927\u7ea68\u5e74\u524d\u5728\u4e2d\u56fd\u521b\u5efa\u4e86\u4e00\u4e2a\u771f\u6b63\u7684\u521b\u65b0\u578b\u751f\u7269\u6280\u672f\u516c\u53f8\u2014\u2014\u534e\u9886\u533b\u836f\uff0c\u5e0c\u671b\u5979\u80fd\u4e3a\u5168\u7403\u7cd6\u5c3f\u75c5\u4eba\u5e26\u6765\u798f\u97f3\u3002&#8221;&nbsp; \u534e\u9886\u533b\u836f\u8463\u4e8b\u957f\u3001ARCH\u98ce\u9669\u6295\u8d44\u521b\u59cb\u4eba\u548c\u5e38\u52a1\u8463\u4e8b\u7f57\u4f2f\u7279.\u5c3c\u5c14\u68ee\u5148\u751f\u8bf4\u3002&#8221;\u968f\u7740HMM0301\u4e34\u5e8a\u7814\u7a7624\u5468\u6838\u5fc3\u6570\u636e\u7684\u4ea7\u751f\uff0c\u534e\u9886\u533b\u836f\u6210\u4e3a\u4e2d\u56fd\u7b2c\u4e00\u4e2a\u5f00\u53d1\u5168\u7403\u9996\u521b\u65b0\u836f\u7684\u751f\u7269\u6280\u672f\u516c\u53f8\uff0c\u80fd\u591f\u5728\u5c55\u793a\u6240\u671f\u671b\u7684\u5b89\u5168\u6307\u6807\u7684\u540c\u65f6\uff0c\u6210\u529f\u8fbe\u5230\u4e3b\u8981\u6cbb\u7597\u7ec8\u70b9\u3002\u8fd9\u5bf9\u534e\u9886\u533b\u836f\u3001\u4e2d\u56fd\u4e34\u5e8a\u7814\u7a76\u8005\u90fd\u662f\u4e00\u4e2a\u91cd\u5927\u7684\u91cc\u7a0b\u7891\uff0c\u66f4\u662f\u5bf9\u5168\u7403\u500d\u906d\u7cd6\u5c3f\u75c5\u82e6\u96be\u6298\u78e8\u7684\u793e\u4f1a\u7fa4\u4f53\u7684\u4e00\u4e2a\u91cd\u5927\u91cc\u7a0b\u7891\u3002&#8221;<\/span><\/p>\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\">\n<p style=\"margin-top: 5px;max-width: 100%;min-height: 1em;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"  \/><\/p>\n<\/section>\n<section class=\"\"  style=\"margin-right: auto;margin-left: auto;max-width: 100%;box-sizing: border-box;width: 656.688px;overflow-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box;display: inline-block;width: 656.688px;vertical-align: top;background-color: rgb(239, 239, 239);overflow-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\">\n<section style=\"padding-right: 0.5em;padding-left: 0.5em;max-width: 100%;box-sizing: border-box;display: inline-block;vertical-align: top;line-height: 3em;text-align: center;color: rgb(255, 255, 255);background-color: rgb(28, 151, 250);border-left: 0.5em solid rgb(28, 151, 250);overflow-wrap: break-word !important;\">\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"  \/><\/p>\n<\/section>\n<section style=\"max-width: 100%;box-sizing: border-box;display: inline-block;vertical-align: top;border-left: 1em solid rgb(28, 151, 250);border-top: 1em solid rgb(28, 151, 250);overflow-wrap: break-word !important;border-right: 1em solid transparent !important;border-bottom: 1em solid transparent !important;\"><\/section>\n<section style=\"max-width: 100%;box-sizing: border-box;display: inline-block;vertical-align: top;line-height: 3em;text-align: left;overflow-wrap: break-word !important;\">\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">HMM0301\u4e34\u5e8a\u7814\u7a76\u8bbe\u8ba1<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"\"  style=\"margin-right: auto;margin-left: auto;max-width: 100%;box-sizing: border-box;width: 663.453px;overflow-wrap: break-word !important;\">\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"  \/><\/p>\n<p style=\"margin-top: 5px;max-width: 100%;min-height: 1em;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;color: rgb(12, 12, 12);overflow-wrap: break-word !important;\">HMM0301\u662f\u5728\u4e2d\u56fd\u4ece\u672a\u63a5\u53d7\u8fc7\u7cd6\u5c3f\u75c5\u836f\u7269\u6cbb\u7597\u76842\u578b\u7cd6\u5c3f\u75c5\u60a3\u8005\u4e2d\u5c55\u5f00\u7684\u968f\u673a\u53cc\u76f2\u3001\u5b89\u6170\u5242\u5bf9\u7167\u7684\u6ce8\u518c\u602752\u5468III\u671f\u4e34\u5e8a\u7814\u7a76\uff0c\u5171\u7eb3\u5165463\u4e3a\u53d7\u8bd5\u8005\u3002\u5176\u4e2d\u524d24\u5468\u4e3a\u968f\u673a\u53cc\u76f2\u3001\u5b89\u6170\u5242\u5bf9\u7167\u7684\u7597\u6548\u548c\u5b89\u5168\u6027\u7814\u7a76\uff0c\u53d7\u8bd5\u8005\u4ee52\uff1a1\u6bd4\u4f8b\u5165\u7ec4\uff0c\u968f\u673a\u63a5\u53d7\u4e00\u5929\u4e24\u6b21\u53e3\u670d75mg dorzagliatin \u6216\u5b89\u6170\u5242\u3002\u540e28\u5468\u4e3a\u5f00\u653e\u5f0f\u6d3b\u6027\u836f\u7269\u6cbb\u7597\u7684\u836f\u7269\u5b89\u5168\u6027\u7814\u7a76\u3002\u540c\u65f6\uff0c\u4e34\u5e8a\u7814\u7a76\u8005\u8d2f\u5f7b\u4e2d\u534e\u533b\u5b66\u4f1a\u7cd6\u5c3f\u75c5\u5b66\u5206\u4f1a\u7684\u6307\u5357\u8981\u6c42\uff0c\u5bf9\u53d7\u8bd5\u8005\u8fdb\u884c\u52a0\u5f3a\u953b\u70bc\u548c\u996e\u98df\u63a7\u5236\uff0c\u5e76\u6309\u65f6\u8fdb\u884c\u81ea\u6211\u8840\u7cd6\u76d1\u63a7\u7684\u6559\u80b2\u3002\u5728\u7b2c24\u5468\u65f6\uff0c\u5bf9dorzagliatin\u7684\u4e3b\u8981\u7597\u6548\u7ec8\u70b9\u8fdb\u884c\u8bc4\u4f30\u3002\u672c\u7814\u7a76\u7531\u4e2d\u534e\u533b\u5b66\u4f1a\u7cd6\u5c3f\u75c5\u5b66\u4f1a\u73b0\u4efb\u4e3b\u4efb\u59d4\u5458\u6731\u5927\u9f99\u6559\u6388\u9886\u8854\uff0c\u5728\u4e2d\u56fd40\u5bb6\u4e34\u5e8a\u4e2d\u5fc3\u5f00\u5c55\u3002\u534e\u9886\u533b\u836f\u9884\u671f\u57282020\u5e74\u7b2c\u4e8c\u5b63\u5ea6\u83b7\u5f9752\u5468\u4e34\u5e8a\u7814\u7a76\u7ed3\u679c\u3002<\/span><\/p>\n<section style=\"max-width: 100%;box-sizing: border-box;line-height: 1.75em;overflow-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"  \/><\/section>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;color: rgb(12, 12, 12);overflow-wrap: break-word !important;\">\u672c\u516c\u53f8\u65e0\u6cd5\u4fdd\u8bc1\u672c\u516c\u53f8\u5c06\u4e8e2020\u5e74\u7b2c\u4e8c\u5b63\u5ea6\u83b7\u5f9752\u5468\u4e34\u5e8a\u7814\u7a76\u7ed3\u679c\u6216\u53ef\u4ee5\u6210\u529f\u5f00\u53d1\u6216\u6700\u7ec8\u6210\u529f\u63a8\u51fadorzagliatin\u3002\u672c\u516c\u53f8\u80a1\u4e1c\u53ca\u6f5c\u5728\u6295\u8d44\u8005\u4e8e\u4e70\u5356\u672c\u516c\u53f8\u80a1\u4efd\u65f6\u52a1\u8bf7\u5ba1\u614e\u884c\u4e8b\u3002<\/span><\/p>\n<\/section>\n<p style=\"margin-right: 5px;margin-left: 5px;max-width: 100%;min-height: 1em;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;color: rgb(12, 12, 12);overflow-wrap: break-word !important;\"><\/span><\/p>\n<\/section>\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;font-size: 14px;line-height: 1.75;color: rgb(89, 89, 89);overflow-wrap: break-word !important;\">\n<p style=\"margin-right: 5px;margin-left: 5px;max-width: 100%;min-height: 1em;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"  \/><\/p>\n<\/section>\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box;font-family: -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;font-size: 16px;letter-spacing: 0.544px;white-space: normal;background-color: rgb(255, 255, 255);overflow-wrap: break-word !important;\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;letter-spacing: 0.544px;overflow-wrap: break-word !important;\">\n<section style=\"margin-top: 10px;margin-bottom: 10px;max-width: 100%;box-sizing: border-box;text-align: left;overflow-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box;display: inline-block;overflow-wrap: break-word !important;\"><span style=\"padding: 0.3em 0.5em;max-width: 100%;box-sizing: border-box;display: block;border-radius: 0.8em 0.8em 0px 0px;background-color: rgb(30, 155, 232);font-size: 14px;color: rgb(255, 255, 255);overflow-wrap: break-word !important;\"><\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 2em;line-height: 2em;overflow-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">&nbsp; &nbsp; &nbsp;\u5173\u4e8e Dorzagliatin&nbsp; &nbsp;&nbsp;<\/strong><\/p>\n<p><\/span><\/section>\n<section style=\"padding: 10px;max-width: 100%;box-sizing: border-box;border-width: 1px;border-style: solid;border-color: rgb(53, 121, 213);border-radius: 0px 0px 0.8em 0.8em;overflow-wrap: break-word !important;\">\n<section class=\"\"  style=\"margin-right: auto;margin-left: auto;max-width: 100%;box-sizing: border-box;width: 655px;overflow-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box;text-align: justify;overflow-wrap: break-word !important;\">\n<p style=\"margin: 10px 15px;max-width: 100%;box-sizing: border-box;min-height: 1em;line-height: 1.75em;text-indent: 0em;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 14px;letter-spacing: 0.544px;color: rgb(12, 12, 12);overflow-wrap: break-word !important;\">Dorzagliatin\u662f\u5168\u7403\u9996\u521b\u53cc\u4f5c\u7528\u7684\u8461\u8404\u7cd6\u6fc0\u9176\u6fc0\u6d3b\u5242\uff0c\u65e8\u5728\u901a\u8fc7\u6062\u590d2\u578b\u7cd6\u5c3f\u75c5\u60a3\u8005\u7684\u8461\u8404\u7cd6\u7a33\u6001\u6765\u63a7\u5236\u7cd6\u5c3f\u75c5\u6e10\u8fdb\u6027\u9000\u53d8\u6027\u75be\u75c5\u53d1\u5c55\u3002\u901a\u8fc7\u4fee\u590d\u8461\u8404\u7cd6\u6fc0\u9176\u7684\u8461\u8404\u7cd6\u4f20\u611f\u5668\u529f\u80fd\u7684\u7f3a\u9677, dorzagliatin\u5177\u6709\u6062\u590d2\u578b\u7cd6\u5c3f\u75c5\u60a3\u8005\u53d7\u635f\u7684\u8840\u7cd6\u7a33\u6001\u72b6\u6001\u4e0b\u7684\u6f5c\u529b\uff0c\u53ef\u4f5c\u4e3a\u6cbb\u7597\u8be5\u75be\u75c5\u7684\u4e00\u7ebf\u62a4\u7406\u6cbb\u7597\u6807\u51c6\uff0c\u6216\u4f5c\u4e3a\u4e0e\u76ee\u524d\u6279\u51c6\u7684\u6297\u7cd6\u5c3f\u75c5\u836f\u7269\u8054\u5408\u4f7f\u7528\u7684\u57fa\u7840\u6cbb\u7597\u3002<\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;letter-spacing: 0.544px;overflow-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\">\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;overflow-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"  \/><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;letter-spacing: 0.544px;overflow-wrap: break-word !important;\">\n<section style=\"margin-top: 10px;margin-bottom: 10px;max-width: 100%;box-sizing: border-box;text-align: left;overflow-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box;display: inline-block;overflow-wrap: break-word !important;\"><span style=\"padding: 0.3em 0.5em;max-width: 100%;box-sizing: border-box;display: block;border-radius: 0.8em 0.8em 0px 0px;background-color: rgb(30, 155, 232);font-size: 14px;color: rgb(255, 255, 255);overflow-wrap: break-word !important;\"><\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 2em;line-height: 2em;overflow-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">&nbsp;&nbsp; \u5173\u4e8e\u534e\u9886&nbsp; &nbsp; &nbsp;<\/strong><\/p>\n<p><\/span><\/section>\n<section style=\"padding: 10px;max-width: 100%;box-sizing: border-box;border-width: 1px;border-style: solid;border-color: rgb(64, 134, 229);border-radius: 0px 0px 0.8em 0.8em;overflow-wrap: break-word !important;\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box;text-align: justify;overflow-wrap: break-word !important;\">\n<p style=\"margin: 10px 15px;max-width: 100%;box-sizing: border-box;min-height: 1em;line-height: 1.75em;text-indent: 0em;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 14px;color: rgb(12, 12, 12);overflow-wrap: break-word !important;\">\u534e\u9886\u533b\u836f\u662f\u4e00\u5bb6\u7acb\u8db3\u4e2d\u56fd\uff0c\u9488\u5bf9\u5168\u7403\u7cd6\u5c3f\u75c5\u60a3\u8005\u5c1a\u672a\u6ee1\u8db3\u7684\u4e34\u5e8a\u9700\u6c42\uff0c\u7814\u53d1\u5168\u7403\u539f\u521b\u65b0\u836f\u7684\u751f\u7269\u6280\u672f\u516c\u53f8\u3002\u534e\u9886\u533b\u836f\u6c47\u805a\u5168\u7403\u9ad8\u7aef\u4eba\u624d\u548c\u79d1\u6280\u8d44\u6e90\uff0c\u4ee5\u56fd\u9645\u9876\u7ea7\u751f\u7269\u533b\u836f\u6295\u8d44\u56e2\u961f\u4e3a\u4f9d\u6258\uff0c\u6210\u529f\u5b9e\u73b0\u4e86\u5168\u7403\u9996\u521b\u7cd6\u5c3f\u75c5\u65b0\u836fdorzagliatin\u5728\u4e2d\u56fd\u5b8c\u6210\u836f\u54c1\u53ef\u5f00\u53d1\u6027\u4e34\u5e8a\u9a8c\u8bc1\uff0c\u7387\u5148\u8fdb\u5165\u6ce8\u518c\u6027\u4e34\u5e8a\u8bd5\u9a8c\u9636\u6bb5\u3002\u76ee\u524d\u516c\u53f8\u5df2\u5728\u4e2d\u56fd\u5f00\u5c552\u4e2aIII\u671f\u4e34\u5e8a\u8bd5\u9a8c\u4ee5\u53ca\u5728\u7f8e\u56fd\u8fdb\u884c2\u4e2aI\u671f\u8bd5\u9a8c\u6cbb\u7597\u6210\u4eba2\u578b\u7cd6\u5c3f\u75c5\u3002\u516c\u53f8\u5c06\u542f\u52a8\u836f\u54c1\u751f\u547d\u5468\u671f\u7ba1\u7406\u76f8\u5173\u4e34\u5e8a\u8bd5\u9a8c\uff0c\u5e76\u62d3\u5c55\u7cd6\u5c3f\u75c5\u4e2a\u6027\u5316\u6cbb\u7597\u548c\u7ba1\u7406\u7684\u5148\u8fdb\u7406\u5ff5\uff0c\u8054\u5408\u4e2d\u56fd\u548c\u7f8e\u56fd\u7cd6\u5c3f\u75c5\u9886\u57df\u4e13\u5bb6\uff0c\u5b9e\u73b0\u5bf9\u7cd6\u5c3f\u75c5\u548c\u4ee3\u8c22\u6027\u75be\u75c5\u53ca\u5176\u5e76\u53d1\u75c7\u7684\u6709\u6548\u63a7\u5236\u3002<\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;font-family: -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;font-size: 16px;letter-spacing: 0.544px;white-space: normal;background-color: rgb(255, 255, 255);overflow-wrap: break-word !important;\">\n<p style=\"max-width: 100%;min-height: 1em;line-height: normal;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"  \/><\/p>\n<section class=\"\"   style=\"max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box;text-align: center;overflow-wrap: break-word !important;\">\n<section style=\"margin-right: auto;margin-left: auto;padding-right: 15px;padding-left: 15px;max-width: 100%;box-sizing: border-box;background-color: rgba(254, 254, 254, 0);display: inline-block;overflow-wrap: break-word !important;\">\n<p style=\"max-width: 100%;min-height: 1em;color: inherit;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"  \/><\/p>\n<\/section>\n<section style=\"margin-top: -12px;margin-bottom: 10px;max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\">\n<section  style=\"max-width: 100%;box-sizing: border-box;border-top: 1px dashed rgb(165, 165, 165);width: 677px;border-right-color: rgb(165, 165, 165);border-bottom-color: rgb(165, 165, 165);border-left-color: rgb(165, 165, 165);overflow-wrap: break-word !important;\"><\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;font-family: -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;font-size: 16px;letter-spacing: 0.544px;white-space: normal;background-color: rgb(255, 255, 255);line-height: 1;color: rgb(89, 89, 89);text-align: left;overflow-wrap: break-word !important;\">\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;color: rgb(165, 165, 165);font-size: 11px;overflow-wrap: break-word !important;\">1. \u6839\u64da\u7f8e\u570b\u7cd6\u5c3f\u75c5\u5354\u6703ADA\u57282019\u5e74\u767c\u4f48\u7684\u7cd6\u5c3f\u75c5\u91ab\u5b78\u8a3a\u7642\u6a19\u6e96\uff08Standards of Medical Care in Diabetes\uff09\uff0c \u4f4e\u8840\u7cd6\u5b9a\u7fa9\u70ba\u8840\u7cd6\u6c34\u5e73\uff1c3.0 mmol\/liter\u3002<\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"  \/><\/p>\n<p style=\"margin-bottom: 15px;max-width: 100%;min-height: 1em;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;color: rgb(165, 165, 165);font-size: 11px;overflow-wrap: break-word !important;\">2. \u6839\u64da\u7f8e\u570b\u7cd6\u5c3f\u75c5\u5354\u6703ADA\u57282019\u5e74\u767c\u4f48\u7684\u7cd6\u5c3f\u75c5\u91ab\u5b78\u8a3a\u7642\u6a19\u6e96\uff08Standards of Medical Care in Diabetes\uff09\uff0c\u56b4\u91cd\u4f4e\u8840\u7cd6\u5b9a\u7fa9\u70ba\u7121\u7279\u5b9a\u7684\u8461\u8404\u7cd6\u95be\u503c\uff0c\u4f34\u6709\u56b4\u91cd\u8a8d\u77e5\u969c\u7919\u7684\u4f4e\u8840\u7cd6\u75c7\uff0c\u9700\u8981\u5916\u90e8\u63f4\u52a9\u624d\u80fd\u6062\u5fa9\u3002<\/span><\/p>\n<\/section>\n<section class=\"\"   style=\"max-width: 100%;box-sizing: border-box;font-family: -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;font-size: 16px;letter-spacing: 0.544px;white-space: normal;background-color: rgb(255, 255, 255);overflow-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box;text-align: center;overflow-wrap: break-word !important;\">\n<section style=\"margin-top: -2px;margin-bottom: 10px;max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\">\n<section  style=\"max-width: 100%;box-sizing: border-box;border-top: 1px dashed rgb(165, 165, 165);width: 677px;border-right-color: rgb(165, 165, 165);border-bottom-color: rgb(165, 165, 165);border-left-color: rgb(165, 165, 165);overflow-wrap: break-word !important;\"><\/section>\n<\/section>\n<\/section>\n<\/section>\n<p style=\"margin-right: 10px;margin-left: 10px;max-width: 100%;min-height: 1em;font-family: -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;letter-spacing: 0.544px;text-indent: 0em;white-space: normal;background-color: rgb(255, 255, 255);box-sizing: border-box !important;overflow-wrap: break-word !important;outline: none 0px !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;font-family: -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;letter-spacing: 0.544px;white-space: normal;background-color: rgb(255, 255, 255);line-height: 1.75em;box-sizing: border-box !important;overflow-wrap: break-word !important;outline: none 0px !important;\"><span style=\"max-width: 100%;line-height: 14.98px;color: rgb(3, 109, 210);font-size: 16px;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;outline: none 0px !important;\">\u5a92\u4f53\u8054\u7cfb\uff1a<\/strong><\/span><\/p>\n<section style=\"margin-top: 5px;max-width: 100%;box-sizing: border-box;font-family: -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;font-size: 16px;letter-spacing: 0.544px;white-space: normal;background-color: rgb(255, 255, 255);width: 574px;float: left;overflow-wrap: break-word !important;\">\n<p style=\"max-width: 100%;min-height: 1em;font-size: 17px;line-height: 1.75em;box-sizing: border-box !important;overflow-wrap: break-word !important;outline: none 0px !important;\"><span style=\"max-width: 100%;overflow-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;line-height: 14.98px;font-size: 14px;color: rgb(12, 12, 12);box-sizing: border-box !important;overflow-wrap: break-word !important;outline: none 0px !important;\">\u4e2d\u56fd:<\/span><\/strong><\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;font-size: 17px;line-height: 1.75em;box-sizing: border-box !important;overflow-wrap: break-word !important;outline: none 0px !important;\"><span style=\"max-width: 100%;line-height: 14.98px;font-size: 14px;color: rgb(12, 12, 12);box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u53f6\u82b3\u6148<\/span><\/p>\n<p style=\"margin-bottom: 5px;max-width: 100%;min-height: 1em;font-size: 17px;line-height: 1.75em;box-sizing: border-box !important;overflow-wrap: break-word !important;outline: none 0px !important;\"><span style=\"max-width: 100%;line-height: 14.98px;font-size: 14px;color: rgb(12, 12, 12);box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u4f01\u4e1a\u878d\u8d44\u90e8\u603b\u76d1<\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;font-size: 17px;line-height: 1.75em;box-sizing: border-box !important;overflow-wrap: break-word !important;outline: none 0px !important;\"><span style=\"max-width: 100%;line-height: 14.98px;font-size: 14px;color: rgb(12, 12, 12);box-sizing: border-box !important;overflow-wrap: break-word !important;\">ir@huamedicine.com<\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;font-size: 17px;line-height: 1.75em;box-sizing: border-box !important;overflow-wrap: break-word !important;outline: none 0px !important;\"><span style=\"max-width: 100%;line-height: 14.98px;font-size: 14px;color: rgb(12, 12, 12);box-sizing: border-box !important;overflow-wrap: break-word !important;\">+86-21-3810-1852<\/span><\/p>\n<\/section>\n<section style=\"margin-top: 5px;max-width: 100%;box-sizing: border-box;font-family: -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;font-size: 16px;letter-spacing: 0.544px;white-space: normal;background-color: rgb(255, 255, 255);width: 574px;float: left;overflow-wrap: break-word !important;\">\n<section style=\"margin-top: 5px;max-width: 100%;box-sizing: border-box;font-size: 17px;line-height: 1.75em;overflow-wrap: break-word !important;outline: none 0px !important;\"><span style=\"max-width: 100%;overflow-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;line-height: 14.98px;font-size: 14px;color: rgb(12, 12, 12);box-sizing: border-box !important;overflow-wrap: break-word !important;outline: none 0px !important;\">\u7f8e\u56fd:<\/span><\/strong><\/span><\/section>\n<section style=\"max-width: 100%;box-sizing: border-box;font-size: 17px;line-height: 1.75em;overflow-wrap: break-word !important;outline: none 0px !important;\"><span style=\"max-width: 100%;line-height: 14.98px;font-size: 14px;color: rgb(12, 12, 12);box-sizing: border-box !important;overflow-wrap: break-word !important;\">Sarah Sutton<\/span><\/section>\n<section style=\"margin-bottom: 5px;max-width: 100%;box-sizing: border-box;font-size: 17px;line-height: 1.75em;overflow-wrap: break-word !important;outline: none 0px !important;\"><span style=\"max-width: 100%;line-height: 14.98px;font-size: 14px;color: rgb(12, 12, 12);box-sizing: border-box !important;overflow-wrap: break-word !important;\">Glover Park Group<\/span><\/section>\n<section style=\"margin-bottom: 5px;max-width: 100%;box-sizing: border-box;font-size: 17px;line-height: 1.75em;overflow-wrap: break-word !important;outline: none 0px !important;\"><span style=\"max-width: 100%;color: rgb(12, 12, 12);font-size: 14px;box-sizing: border-box !important;overflow-wrap: break-word !important;\">ssutton@gpg.com&nbsp;<\/span><\/section>\n<section style=\"max-width: 100%;box-sizing: border-box;font-size: 17px;line-height: 1.75em;overflow-wrap: break-word !important;outline: none 0px !important;\"><span style=\"max-width: 100%;line-height: 14.98px;font-size: 14px;color: rgb(12, 12, 12);box-sizing: border-box !important;overflow-wrap: break-word !important;\">+1 202-337-0808<\/span><\/section>\n<p><br  \/><\/p>\n<\/section>\n<\/section>\n<p style=\"margin-right: 8px;margin-left: 8px;max-width: 100%;min-height: 1em;font-family: -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;letter-spacing: 0.544px;white-space: normal;background-color: rgb(255, 255, 255);font-size: 16px;text-align: left;line-height: 1.5em;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><img class=\"rich_pages\"      style=\"box-sizing: border-box !important;overflow-wrap: break-word !important;visibility: visible !important;width: 592px !important;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2020\/04\/5-1587430064.jpeg\" alt=\"\u534e\u9886\u533b\u836fDorzagliatin\u5355\u836f\u6cbb\u7597III\u671f\u6ce8\u518c\u4e34\u5e8a\u7814\u7a76(HMM0301)\u8fbe\u5230\u7814\u7a76\u4e3b\u8981\u7597\u6548\u7ec8\u70b9\uff01\" title=\"\u534e\u9886\u533b\u836fDorzagliatin\u5355\u836f\u6cbb\u7597III\u671f\u6ce8\u518c\u4e34\u5e8a\u7814\u7a76(HMM0301)\u8fbe\u5230\u7814\u7a76\u4e3b\u8981\u7597\u6548\u7ec8\u70b9\uff01\"  \/><\/p>\n<section class=\"\" mpa-from-tpl=\"t\" style=\"max-width: 100%;letter-spacing: 0.544px;white-space: normal;background-color: rgb(255, 255, 255);font-size: 16px;font-family: -apple-system-font, BlinkMacSystemFont, Arial, sans-serif;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<section mpa-from-tpl=\"t\" class=\"\" style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<section  mpa-from-tpl=\"t\" class=\"\"   style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<section  mpa-from-tpl=\"t\" style=\"max-width: 100%;width: 574px;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<section mpa-from-tpl=\"t\" style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<section mpa-from-tpl=\"t\" style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<section class=\"\" mpa-from-tpl=\"t\" style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<section class=\"\"    mpa-from-tpl=\"t\" style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<section mpa-from-tpl=\"t\" style=\"margin: 30px auto;padding: 25px 20px;max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;background-color: rgb(247, 247, 247);\">\n<section  class=\"\" mpa-from-tpl=\"t\" style=\"max-width: 100%;font-size: 14px;color: rgb(79, 79, 79);box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<p style=\"margin-right: 8px;margin-left: 8px;max-width: 100%;min-height: 1em;text-align: center;line-height: 1.5em;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><img class=\"rich_pages\"           style=\"box-sizing: border-box !important;overflow-wrap: break-word !important;visibility: visible !important;width: 79px !important;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2020\/04\/7-1587430064.jpeg\" alt=\"\u534e\u9886\u533b\u836fDorzagliatin\u5355\u836f\u6cbb\u7597III\u671f\u6ce8\u518c\u4e34\u5e8a\u7814\u7a76(HMM0301)\u8fbe\u5230\u7814\u7a76\u4e3b\u8981\u7597\u6548\u7ec8\u70b9\uff01\" title=\"\u534e\u9886\u533b\u836fDorzagliatin\u5355\u836f\u6cbb\u7597III\u671f\u6ce8\u518c\u4e34\u5e8a\u7814\u7a76(HMM0301)\u8fbe\u5230\u7814\u7a76\u4e3b\u8981\u7597\u6548\u7ec8\u70b9\uff01\"  \/><\/p>\n<p style=\"margin-right: 8px;margin-left: 8px;max-width: 100%;min-height: 1em;line-height: 1.5em;text-align: left;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;color: rgb(136, 136, 136);letter-spacing: 1px;font-size: 15px;box-sizing: border-box !important;overflow-wrap: break-word 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 \/><\/p>\n<\/p><\/div>\n","protected":false},"excerpt":{"rendered":"<p>\u201c\u672c\u6587\u6765\u6e90\u4e8e\u534e\u9886\u533b\u836f\u5fae\u4fe1\u516c\u4f17\u53f7\uff08ID\uff1ahuamedicine )\u201d Dorzagliatin\u5355\u836f\u6cbb\u7597III\u671f\u6ce8 [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":120969,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[2],"tags":[],"_links":{"self":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/120968"}],"collection":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/comments?post=120968"}],"version-history":[{"count":1,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/120968\/revisions"}],"predecessor-version":[{"id":120974,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/120968\/revisions\/120974"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/media\/120969"}],"wp:attachment":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/media?parent=120968"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/categories?post=120968"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/tags?post=120968"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}