{"id":125260,"date":"2019-09-16T22:56:50","date_gmt":"2020-04-21T02:06:22","guid":{"rendered":"http:\/\/www.05921.net\/index.php\/125260\/"},"modified":"2020-04-21T10:06:24","modified_gmt":"2020-04-21T02:06:24","slug":"47b2e9b467","status":"publish","type":"post","link":"https:\/\/www.05921.net\/index.php\/125260\/","title":{"rendered":"\u5973\u533b\u751f\u4e0a\u73ed\u5f00\u76f4\u64ad\uff0c\u536b\u5065\u5c40\uff1a\u4e34\u8058\u4eba\u5458\uff0c\u5df2\u6279\u8bc4\u5e76\u6263\u51cf\u7ee9\u6548\u200b\u200b | \u4e01\u9999\u65e9\u8bfb"},"content":{"rendered":"
\n

\"\u5973\u533b\u751f\u4e0a\u73ed\u5f00\u76f4\u64ad\uff0c\u536b\u5065\u5c40\uff1a\u4e34\u8058\u4eba\u5458\uff0c\u5df2\u6279\u8bc4\u5e76\u6263\u51cf\u7ee9\u6548\u200b\u200b<\/span><\/strong>
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\u6bcf\u4e2a\u5de5\u4f5c\u65e5\u65e9\u6668<\/span><\/p>\n

\u4e01\u9999\u65e9\u8bfb<\/strong><\/span> <\/span>\u51c6\u65f6\u66f4\u65b0<\/span><\/p>\n

\u7b2c\u4e00\u65f6\u95f4 \u8ffd\u8e2a\u533b\u7597\u70ed\u70b9<\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n


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\u5973\u533b\u751f\u4e0a\u73ed\u5f00\u76f4\u64ad\uff0c\u536b\u5065\u5c40\uff1a<\/strong><\/span>\u4e34\u8058\u4eba\u5458\uff0c\u5df2\u6279\u8bc4\u5e76\u6263\u51cf\u7ee9\u6548<\/strong><\/span><\/h1>\n


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\u6700\u8fd1\uff0c\u6709\u7f51\u53cb\u7206\u6599\u79f0\uff0c\u6709\u4e00\u7a7f\u767d\u5927\u8902\u7684\u5973\u533b\u751f\u4e0a\u73ed\u65f6\u95f4\u5f00\u76f4\u64ad\uff0c\u81ea\u79f0\u662f\u56db\u5ddd\u4e50\u5c71\u4eba\uff0c\u5728\u533b\u9662\u4fdd\u5065\u79d1\u4e0a\u73ed\u3002<\/span>\u7f51\u53cb\u8868\u793a\uff0c\u8be5\u884c\u4e3a\u5f71\u54cd\u767d\u8863\u5929\u4f7f\u5f62\u8c61\u548c\u793e\u4f1a\u98ce\u6c14\uff0c\u5e0c\u671b\u6709\u5173\u90e8\u95e8\u8fdb\u884c\u8c03\u67e5\u5904\u7406\u3002<\/span><\/section>\n

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\"\u5973\u533b\u751f\u4e0a\u73ed\u5f00\u76f4\u64ad\uff0c\u536b\u5065\u5c40\uff1a\u4e34\u8058\u4eba\u5458\uff0c\u5df2\u6279\u8bc4\u5e76\u6263\u51cf\u7ee9\u6548\u200b\u200b<\/section>\n
\u56fe\u7247\u6765\u6e90\uff1a\u6f8e\u6e43\u65b0\u95fb<\/span><\/section>\n

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9 \u6708 16 \u65e5\uff0c\u4e50\u5c71\u5e02\u9a6c\u8fb9\u5f5d\u65cf\u81ea\u6cbb\u53bf\u536b\u5065\u5c40\u56de\u5e94\u79f0\uff0c\u521d\u6b65\u67e5\u660e\u89c6\u9891\u4e2d\u7684\u76f4\u64ad\u4eba\u5458\u4e3a\u8001\u6cb3\u575d\u4e61\u536b\u751f\u9662\u4e34\u8058\u4eba\u5458\u738b\u67d0\u67d0\uff0c\u4e3b\u8981\u4ece\u4e8b\u57fa\u672c\u516c\u5171\u536b\u751f\u670d\u52a1\u3002<\/span>\u738b\u67d0\u67d0\u65e0\u89c6\u533b\u9662\u5de5\u4f5c\u7eaa\u5f8b\u53ca\u76f8\u5173\u5236\u5ea6\uff0c\u5728\u804c\u5de5\u5bbf\u820d\u7a7f\u7740\u533b\u9662\u5de5\u4f5c\u670d\u5728\u964c\u964c\u5e73\u53f0\u76f4\u64ad\uff0c\u635f\u5bb3\u4e86\u533b\u52a1\u4eba\u5458\u7684\u793e\u4f1a\u5f62\u8c61\u3002<\/span><\/section>\n


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\u76ee\u524d\uff0c\u8be5\u5c40\u5df2\u8d23\u4ee4\u8001\u6cb3\u575d\u4e61\u536b\u751f\u9662\u5bf9\u738b\u67d0\u67d0\u4f5c\u51fa\u4e25\u8083\u6279\u8bc4\u6559\u80b2\u5e76\u6263\u51cf\u5176\u534a\u5e74\u7ee9\u6548\u5de5\u8d44\uff1b<\/span>\u5bf9\u8be5\u9662\u516c\u5171\u536b\u751f\u79d1\u79d1\u957f\u4f5c\u51fa\u6279\u8bc4\u6559\u80b2\u5e76\u6263\u51cf\u5f53\u6708\u7ee9\u6548\u3002<\/span>\u540c\u65f6\uff0c\u8d23\u4ee4\u8001\u6cb3\u575d\u4e61\u536b\u751f\u9662\u9662\u957f\u5411\u5c40\u515a\u7ec4\u4f5c\u51fa\u6df1\u523b\u4e66\u9762\u68c0\u67e5\u3002<\/span>\uff08\u6765\u6e90\uff1a<\/span>\u6f8e\u6e43\u65b0\u95fb\uff09<\/span><\/section>\n

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\u6570\u767e\u540d\u8bba\u6587\u5ba1\u7a3f\u4eba\u906d\u7231\u601d\u552f\u5c14\u8c03\u67e5\uff0c\u7591\u5b58\u5728\u300c\u5f3a\u5236\u5f15\u7528\u300d\u884c\u4e3a<\/strong><\/span><\/span><\/h2>\n


<\/p>\n

\u8fd1\u65e5\uff0c\u5b66\u672f\u51fa\u7248\u5de8\u5934\u7231\u601d\u552f\u5c14<\/span>\uff08Elsevier\uff09<\/span>\u8868\u793a\uff0c\u5df2\u5f00\u5c55\u5bf9\u6570\u767e\u540d\u8bba\u6587\u5ba1\u7a3f\u4eba\u7684\u8c03\u67e5\uff0c\u8fd9\u4e9b\u5ba1\u7a3f\u4eba\u88ab\u6000\u7591\u4ee5\u8bc4\u5ba1\u610f\u89c1\u4e3a\u6761\u4ef6\uff0c\u5f3a\u8feb\u88ab\u5ba1\u7a3f\u7684\u4f5c\u8005\u5f15\u7528\u81ea\u5df1\u7684\u8bba\u6587\uff0c\u5373\u300c\u5f3a\u5236\u5f15\u7528\u300d\u3002<\/span><\/section>\n

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\"\u5973\u533b\u751f\u4e0a\u73ed\u5f00\u76f4\u64ad\uff0c\u536b\u5065\u5c40\uff1a\u4e34\u8058\u4eba\u5458\uff0c\u5df2\u6279\u8bc4\u5e76\u6263\u51cf\u7ee9\u6548\u200b\u200b<\/section>\n
\u56fe\u7247\u6765\u6e90\uff1aSSRN \u7f51\u7ad9\u622a\u56fe<\/span><\/section>\n

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\u8fd9\u4e00\u4e8b\u4ef6\u59cb\u4e8e 9 \u6708 6 \u65e5\uff0c\u7231\u601d\u552f\u5c14\u4e24\u540d\u6570\u636e\u5206\u6790\u4e13\u5bb6\u53d1\u5e03\u7684\u4e00\u9879\u7814\u7a76\uff0c\u8be5\u7814\u7a76\u5bf9\u7ea6 55 \u4e07\u540d\u5ba1\u7a3f\u8005\u53ca\u5176\u6240\u8bc4\u5ba1\u7684\u8bba\u6587\u8fdb\u884c\u4e86\u5206\u6790\uff0c\u7ed3\u679c\u663e\u793a\uff0c\u6709 433 \u4f4d\u5ba1\u7a3f\u8005\u53ef\u80fd\u5b58\u5728\u300c\u5f3a\u5236\u5f15\u7528\u300d\u884c\u4e3a\uff0c\u56e0\u4e3a\u4ed6\u4eec\u8bc4\u5ba1\u7684\u6bcf\u7bc7\u8bba\u6587\u90fd\u5f15\u7528\u4e86\u81ea\u5df1\u7684\u7814\u7a76\u3002<\/span><\/section>\n


<\/p>\n

\u7231\u601d\u552f\u5c14\u8868\u793a\uff0c\u5982\u679c\u300c\u5f3a\u5236\u5f15\u7528\u300d\u7684\u60c5\u51b5\u5c5e\u5b9e\uff0c\u90a3\u4e48\u90e8\u5206\u5f15\u7528\u4e86\u5ba1\u7a3f\u4eba\u7814\u7a76\u7684\u8bba\u6587\u53ef\u80fd\u4f1a\u88ab\u64a4\u7a3f\u3002\u540c\u65f6\uff0c\u7231\u601d\u552f\u5c14\u8fd8\u8868\u793a\uff0c\u8fd9\u4e00\u95ee\u9898\u7684\u4e3b\u8981\u8d23\u4efb\u4e0d\u5728\u4e8e\u4f5c\u8005\uff0c\u5728\u672a\u5f71\u54cd\u7814\u7a76\u8d28\u91cf\u7684\u60c5\u51b5\u4e0b\uff0c\u4e0d\u4f1a\u64a4\u56de\u53d7\u300c\u5f3a\u5236\u5f15\u7528\u300d\u5f71\u54cd\u7684\u8bba\u6587\u3002<\/span><\/span><\/span>\u76ee\u524d\u5c1a\u4e0d\u660e\u786e\u6d89\u4e8b\u5ba1\u7a3f\u4eba\u4f1a\u53d7\u5230\u600e\u6837\u7684\u5904\u7f5a\u3002<\/span><\/span>\uff08\u6765\u6e90\uff1aSSRN\uff09<\/span><\/span><\/section>\n

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\u7f8e\u56fd FDA\uff1a<\/strong>\u6297\u80c3\u9178\u836f\u7269\u96f7\u5c3c\u66ff\u4e01\u4e2d\u542b\u4f4e\u6d53\u5ea6\u81f4\u764c\u7269<\/strong><\/span><\/section>\n


<\/p>\n

9 \u6708 13 \u65e5\uff0c\u7f8e\u56fd FDA \u53d1\u5e03\u516c\u544a\u79f0\uff0c\u591a\u4e2a\u54c1\u724c\u751f\u4ea7\u7684\u96f7\u5c3c\u66ff\u4e01<\/a>\u4e2d\u542b\u6709\u4f4e\u6d53\u5ea6\u7684\u53ef\u80fd\u81f4\u764c\u7269 <\/span>N-\u4e9a\u785d\u57fa\u4e8c\u7532\u80fa<\/span>\uff08NDMA\uff09<\/span>\uff0c\u8be5\u7269\u8d28\u4e00\u822c\u5b58\u5728\u4e8e\u6c34\u548c\u98df\u7269\u4e2d\u3002<\/span><\/section>\n

<\/span><\/section>\n
\"\u5973\u533b\u751f\u4e0a\u73ed\u5f00\u76f4\u64ad\uff0c\u536b\u5065\u5c40\uff1a\u4e34\u8058\u4eba\u5458\uff0c\u5df2\u6279\u8bc4\u5e76\u6263\u51cf\u7ee9\u6548\u200b\u200b<\/section>\n
\u56fe\u7247\u6765\u6e90\uff1a\u7f8e\u56fd FDA \u7f51\u7ad9\u622a\u56fe<\/span>
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\u636e\u6089\uff0c\u96f7\u5c3c\u66ff\u4e01\u65e2\u662f\u975e\u5904\u65b9\u836f<\/span>\uff08OTC\uff09<\/span>\u53c8\u662f\u5904\u65b9\u836f\uff0c\u4f5c\u4e3a\u975e\u5904\u65b9\u836f\u65f6\uff0c\u53ef\u7528\u4e8e\u9884\u9632\u548c\u7f13\u89e3\u4e0e\u9178\u6444\u5165\u548c\u80c3\u9178\u6709\u5173\u7684\u80c3\u707c\u70ed\u3002\u4f5c\u4e3a\u5904\u65b9\u836f\u65f6\uff0c\u53ef\u6cbb\u7597\u548c\u9884\u9632\u80c3\u548c\u80a0\u6e83\u75a1\u4ee5\u53ca\u6cbb\u7597\u80c3\u98df\u7ba1\u53cd\u6d41\u75c5\u3002<\/span><\/section>\n


<\/p>\n

\u76ee\u524d\uff0cFDA \u5e76\u6ca1\u6709\u8981\u6c42\u4eba\u4eec\u505c\u6b62\u670d\u7528\u96f7\u5c3c\u66ff\u4e01\uff0c\u800c\u662f\u5efa\u8bae\u670d\u7528\u5904\u65b9\u836f\u96f7\u5c3c\u66ff\u4e01\u7684\u4eba\u300c\u8003\u8651\u4f7f\u7528\u5176\u4ed6\u6709\u6548\u7684\u975e\u5904\u65b9\u836f\u7269\u300d\u3002FDA \u8868\u793a\uff0c\u6b63\u5728\u8bc4\u4f30\u96f7\u5c3c\u66ff\u4e01\u4e2d\u4f4e\u6c34\u5e73\u7684 NDMA \u662f\u5426\u4f1a\u5bf9\u60a3\u8005\u6784\u6210\u98ce\u9669\u3002<\/span>\uff08\u6765\u6e90\uff1a\u7f8e\u56fd FDA\uff09<\/span><\/span><\/section>\n


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<\/p>\n

Nature<\/strong><\/span><\/em>\uff1a\u836f\u7269\u53ef\u4f7f<\/strong>\u4eba\u4f53\u751f\u7406\u5e74\u9f84\u4e0b\u964d 2.5 \u5c81<\/strong><\/span><\/section>\n


<\/p>\n

9 \u6708 5 \u65e5\uff0cNature <\/em>\u53d1\u8868\u7684\u4e00\u7bc7\u7814\u7a76\u663e\u793a\uff0c9 \u540d\u5fd7\u613f\u8005\u670d\u7528\u751f\u957f\u6fc0\u7d20\u3001\u8131\u6c22\u8868\u96c4\u916e<\/span>\uff08DHEA\uff09<\/span>\u4ee5\u53ca\u4e8c\u7532\u53cc\u80cd 1 \u5e74\u540e\uff0c\u751f\u7406\u5e74\u9f84\u5e73\u5747\u4e0b\u964d 2.5 \u5c81\uff0c\u514d\u75ab\u7cfb\u7edf\u4e5f\u663e\u793a\u51fa\u6062\u590d\u6d3b\u529b\u7684\u8ff9\u8c61\uff0c\u505c\u836f 6 \u4e2a\u6708\u540e\uff0c\u8fd9\u79cd\u751f\u7406\u5e74\u9f84\u9006\u8f6c\u7684\u60c5\u5f62\u4ecd\u65e7\u5b58\u5728\u3002<\/span><\/section>\n

<\/span><\/section>\n
\"\u5973\u533b\u751f\u4e0a\u73ed\u5f00\u76f4\u64ad\uff0c\u536b\u5065\u5c40\uff1a\u4e34\u8058\u4eba\u5458\uff0c\u5df2\u6279\u8bc4\u5e76\u6263\u51cf\u7ee9\u6548\u200b\u200b<\/section>\n
\u56fe\u7247\u6765\u6e90\uff1aNature <\/em>\u7f51\u7ad9\u622a\u56fe<\/span><\/section>\n

<\/span><\/section>\n
\u7814\u7a76\u4eba\u5458\u8868\u793a\uff0c\u751f\u957f\u6fc0\u7d20\u80fd\u591f\u523a\u6fc0\u80f8\u817a\u7684\u518d\u751f\uff0c\u4e8c\u7532\u53cc\u80cd\u5728\u9884\u9632\u764c\u75c7\u548c\u5fc3\u810f\u75c5\u4e0a\u4e5f\u5177\u6709\u6781\u5927\u6f5c\u529b\u3002\u8fd9 3 \u79cd\u836f\u7269\u90fd\u53ef\u80fd\u901a\u8fc7\u72ec\u7279\u7684\u673a\u5236\uff0c\u5ef6\u7f13\u751f\u7406\u5e74\u9f84\u7684\u589e\u957f\u3002<\/span><\/section>\n


<\/p>\n

\u6b64\u5916\uff0c\u7814\u7a76\u4eba\u5458\u4e5f\u8868\u793a\uff0c\u8be5\u8bd5\u9a8c\u89c4\u6a21\u5f88\u5c0f\uff0c\u4e14\u4ecd\u5904\u4e8e\u521d\u6b65\u7814\u7a76\u9636\u6bb5\uff0c\u4e0b\u4e00\u6b65\u4ed6\u4eec\u5c06\u62d3\u5c55\u7814\u7a76\u89c4\u6a21\uff0c\u628a\u7814\u7a76\u5bf9\u8c61\u6269\u5c55\u5230\u4e0d\u540c\u5e74\u9f84\u7ec4\u3001\u4e0d\u540c\u79cd\u65cf\u4ee5\u53ca\u4e0d\u540c\u6027\u522b\u3002<\/span>\uff08\u6765\u6e90\uff1a<\/span>Nature<\/em> \uff09<\/span><\/span><\/section>\n


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\n
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\u7b2c<\/span> 270<\/strong><\/span> \u671f\u4e01\u9999\u65e9\u8bfb\u5230\u6b64\u7ed3\u675f<\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n


<\/p>\n

\u8d23\u4efb\u7f16\u8f91\uff1a\u9648\u4ee5\u5bd2<\/span><\/p>\n

\u9898\u56fe\u6765\u6e90\uff1a<\/span>\u7ad9\u9177\u6d77\u6d1b<\/span><\/span><\/p>\n


<\/p>\n

\u6b22\u8fce\u5411\u62a5\u6599\uff01<\/span><\/em><\/span>\u8bf7\u52a0\u5fae\u4fe1\uff1adxylzzb<\/span><\/em><\/p>\n


<\/p>\n

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