{"id":133104,"date":"2020-02-10T03:34:54","date_gmt":"2020-04-21T03:19:12","guid":{"rendered":"http:\/\/www.05921.net\/index.php\/133104\/"},"modified":"2020-04-21T11:19:19","modified_gmt":"2020-04-21T03:19:19","slug":"d69b6f7e55","status":"publish","type":"post","link":"https:\/\/www.05921.net\/index.php\/133104\/","title":{"rendered":"\u4e3a\u4ec0\u4e48\u4e0d\u80fd\u8bf4\u65b0\u578b\u51a0\u72b6\u75c5\u6bd2\u5c5e\u4e8e SARS \u51a0\u72b6\u75c5\u6bd2\uff1f"},"content":{"rendered":"
\n

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\u672c\u6587\u4f5c\u8005\uff1aEVEE<\/span>
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\u6628\u665a\uff0c\u4e5f\u8bb8\u6709\u4e0d\u5c11\u4eba\u5bf9\u4e8e\u65b0\u578b\u51a0\u72b6\u75c5\u6bd2\u7684\u5206\u7c7b\u4ea7\u751f\u4e86\u4e00\u4e9b\u7591\u95ee\u3002<\/span><\/p>\n


<\/span><\/p>\n

\u4e3a\u4ec0\u4e48\u6211\u4eec\u4e0d\u80fd\u8bf4\u65b0\u578b\u51a0\u72b6\u75c5\u6bd2\u5c5e\u4e8e SARS \u51a0\u72b6\u75c5\u6bd2\uff1f\u65b0\u578b\u51a0\u72b6\u75c5\u6bd2\u5230\u5e95\u300c\u65b0\u578b\u300d\u5728\u54ea\u91cc\uff1f\u540c\u6837\u5c5e\u4e8e\u51a0\u72b6\u75c5\u6bd2\uff0c\u5b83\u548c SARS \u51a0\u72b6\u75c5\u6bd2\u53c8\u6709\u4ec0\u4e48\u5173\u7cfb\u5462\uff1f<\/span><\/p>\n


<\/span><\/p>\n

\u4e3a\u4e86\u89e3\u7b54\u8fd9\u4e9b\u95ee\u9898\uff0c\u6211\u4eec\u5f97\u5148\u4ece\u51a0\u72b6\u75c5\u6bd2\u8c08\u8d77\u3002<\/span><\/p>\n


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2019-nCoV \u548c SARS-CoV \u4e4b\u95f4\u662f\u5565\u5173\u7cfb\uff1f<\/span><\/strong><\/span><\/p>\n


<\/p>\n

\u51a0\u72b6\u75c5\u6bd2\u662f\u4e00\u5927\u7c7b\u5728\u81ea\u7136\u754c\u5e7f\u6cdb\u5b58\u5728\u7684\u75c5\u6bd2\u7684\u603b\u79f0\u3002\u51a0\u72b6\u75c5\u6bd2\u6700\u65e9\u4e8e 1968 \u5e74\u88ab\u53d1\u73b0\uff0c\u5e76\u4e8e 1975 \u5e74\u88ab\u56fd\u9645\u75c5\u6bd2\u547d\u540d\u59d4\u5458\u4f1a\u6b63\u5f0f\u547d\u540d\u51a0\u72b6\u75c5\u6bd2\u79d1\u3002<\/span><\/p>\n


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\"\u4e3a\u4ec0\u4e48\u4e0d\u80fd\u8bf4\u65b0\u578b\u51a0\u72b6\u75c5\u6bd2\u5c5e\u4e8e<\/section>\n

\u4eba\u51a0\u72b6\u75c5\u6bd2\u7684\u5206\u5e03\uff08\u56fe\u6e90\uff1aTrends in Microbiology\uff09<\/span><\/p>\n


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\u51a0\u72b6\u75c5\u6bd2\u76f4\u5f84\u7ea6 80\uff5e120nm\uff0c\u5728\u7535\u955c\u4e0b\u53ef\u4ee5\u89c2\u5bdf\u5230\u5b83\u4eec\u7684\u8868\u9762\u6709\u7c7b\u4f3c\u65e5\u5195\u7684\u653e\u5c04\u72b6\u7a81\u8d77\uff0c\u5c31\u50cf\u738b\u51a0\u4e00\u6837\uff0c\u6545\u800c\u88ab\u547d\u540d\u4e3a\u51a0\u72b6\u75c5\u6bd2\u3002<\/span><\/p>\n


<\/p>\n

\"\u4e3a\u4ec0\u4e48\u4e0d\u80fd\u8bf4\u65b0\u578b\u51a0\u72b6\u75c5\u6bd2\u5c5e\u4e8e<\/section>\n

\u65b0\u578b\u51a0\u72b6\u75c5\u6bd2\u7684\u7535\u955c\u7167\u7247\uff08\u56fe\u6e90\uff1a\u4e2d\u56fd\u75be\u75c5\u9884\u9632\u63a7\u5236\u4e2d\u5fc3\uff09<\/span><\/p>\n


<\/span><\/p>\n

\u51a0\u72b6\u75c5\u6bd2\u57fa\u56e0\u7ec4\u7684 5\u2032 \u7aef\u5177\u6709\u7532\u57fa\u5316\u7684\u5e3d\u72b6\u7ed3\u6784\uff0c3\u2032 \u7aef\u5177\u6709 poly(A) \u5c3e\uff0c\u57fa\u56e0\u7ec4\u5168\u957f\u7ea6 27-32kb\uff0c\u662f\u76ee\u524d\u5df2\u77e5 RNA \u75c5\u6bd2\u4e2d\u57fa\u56e0\u7ec4\u6700\u5927\u7684\u75c5\u6bd2\u3002<\/span><\/p>\n


<\/p>\n

\"\u4e3a\u4ec0\u4e48\u4e0d\u80fd\u8bf4\u65b0\u578b\u51a0\u72b6\u75c5\u6bd2\u5c5e\u4e8e<\/section>\n

\u03b1\u3001\u03b2\u3001\u03b3 \u5c5e\u51a0\u72b6\u75c5\u6bd2\u7684\u57fa\u56e0\u7ec4\u7ed3\u6784\uff08\u56fe\u6e90\uff1a<\/span>Coronaviruses\uff09<\/span>
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\u4ece\u7cfb\u7edf\u5206\u7c7b\u7684\u89d2\u5ea6\uff0c\u51a0\u72b6\u75c5\u6bd2\u5c5e\u4e8e\u7f51\u5de2\u75c5\u6bd2\u76ee\uff08Nidovirales<\/em>\uff09\uff0c\u51a0\u72b6\u75c5\u6bd2\u79d1\uff08Coronaviridae<\/em>\uff09\uff0c\u51a0\u72b6\u75c5\u6bd2\u5c5e\uff08Coronavirus<\/em>\uff09\u3002<\/span><\/p>\n


<\/span><\/p>\n

\u6839\u636e\u7cfb\u7edf\u53d1\u751f\u5206\u6790\uff0c\u6211\u4eec\u53ef\u4ee5\u5c06\u51a0\u72b6\u75c5\u6bd2\u5206\u4e3a\u56db\u4e2a\u5c5e\uff1a\u03b1\u3001\u03b2\u3001\u03b3\u3001\u03b4\uff0c\u5176\u4e2d \u03b2 \u5c5e\u51a0\u72b6\u75c5\u6bd2\u53c8\u53ef\u5206\u4e3a\u56db\u4e2a\u72ec\u7acb\u7684\u4e9a\u7fa4 A\u3001B\u3001C \u548c D \u7fa4\u3002\u611f\u67d3\u54fa\u4e73\u52a8\u7269\u7684\u51a0\u72b6\u75c5\u6bd2\u4e3b\u8981\u4e3a \u03b1\u3001\u03b2 \u5c5e\u51a0\u72b6\u75c5\u6bd2\uff1b\u611f\u67d3\u79bd\u7c7b\u7684\u51a0\u72b6\u75c5\u6bd2\u4e3b\u8981\u6765\u6e90\u4e8e \u03b3\u3001\u03b4 \u5c5e\u51a0\u72b6\u75c5\u6bd2\u3002<\/span><\/p>\n


<\/p>\n

\"\u4e3a\u4ec0\u4e48\u4e0d\u80fd\u8bf4\u65b0\u578b\u51a0\u72b6\u75c5\u6bd2\u5c5e\u4e8e<\/section>\n

\u56fe\u6e90\uff1a\u4e2d\u56fd\u75be\u75c5\u9884\u9632\u63a7\u5236\u4e2d\u5fc3<\/span><\/p>\n


<\/span><\/p>\n

\u8fc4\u4eca\u4e3a\u6b62\u88ab\u53d1\u73b0\u7684\u51a0\u72b6\u75c5\u6bd2\u4e2d\uff08\u5305\u62ec\u672c\u6b21\u53d1\u73b0\u7684 2019-nCoV\uff09\uff0c\u76ee\u524d\u53ea\u53d1\u73b0 7 \u79cd\u53ef\u4ee5\u8ba9\u4eba\u7c7b\u611f\u67d3\u3002\u5176\u4e2d\uff0cHCoV-229E \u548c HCoV-NL63 \u5c5e\u4e8e\u03b1 \u5c5e\u51a0\u72b6\u75c5\u6bd2\uff0cHCoV-OC43\u3001SARS-CoV\u3001HCoV-HKU1 \u3001MERS-CoV \u548c 2019-nCoV \u90fd\u5c5e\u4e8e \u03b2 \u5c5e\u51a0\u72b6\u75c5\u6bd2\u3002 <\/span><\/p>\n


<\/p>\n

\"\u4e3a\u4ec0\u4e48\u4e0d\u80fd\u8bf4\u65b0\u578b\u51a0\u72b6\u75c5\u6bd2\u5c5e\u4e8e<\/section>\n

\u56fe\u7247\u6765\u6e90\uff1awww.cdc.gov<\/span><\/p>\n


<\/p>\n

\u6beb\u65e0\u7591\u95ee\uff0c<\/span>\u867d\u7136 SARS-CoV \u548c 2019-nCoV<\/span> \u4e24\u4e2a\u75c5\u6bd2\u90fd\u5c5e\u4e8e \u03b2 \u5c5e\u51a0\u72b6\u75c5\u6bd2\uff0c\u4f46\u4e24\u8005\u5e76\u4e0d\u7b49\u540c\u3002<\/strong><\/span><\/p>\n


<\/span><\/p>\n

\"\u4e3a\u4ec0\u4e48\u4e0d\u80fd\u8bf4\u65b0\u578b\u51a0\u72b6\u75c5\u6bd2\u5c5e\u4e8e<\/section>\n
\u56fe\u7247\u6765\u6e90\uff1a\u4e2d\u56fd\u79d1\u5b66<\/span>
<\/section>\n


<\/p>\n

\u636e\u7b2c\u4e00\u8d22\u7ecf\u6d88\u606f\uff0c\u949f\u5357\u5c71\u9662\u58eb\u8868\u793a\uff0cSARS \u51a0\u72b6\u75c5\u6bd2\u662f\u4e00\u4e2a\u4e13\u6709\u540d\u8bcd\uff0c\u662f\u4e13\u95e8\u6307\u6025\u6027\u547c\u5438\u7efc\u5408\u5f81\u7684\u75c5\u6bd2\uff0c\u5b83\uff08\u4e0e\u65b0\u578b\u51a0\u72b6\u75c5\u6bd2\uff09\u4e0d\u662f\u4e00\u56de\u4e8b\uff0c\u8fd9\u4e24\u4e2a\uff08\u75c5\u6bd2\uff09\u662f\u4e24\u56de\u4e8b\uff0c\u300c2019\uff08\u7684\uff09\u65b0\u578b\u51a0\u72b6\u75c5\u6bd2\u662f\u53e6\u5916\u4e00\u79cd\u75c5\u6bd2\uff0c\u90fd\u662f\u5c5e\u4e8e\u51a0\u72b6\u75c5\u6bd2\u3002\u300d<\/span><\/span><\/p>\n


<\/p>\n

\u4ece\u5206\u7c7b\u89d2\u5ea6\u6765\u8bf4\uff0c<\/span>2019-nCoV \u4e0e SARS \u75c5\u6bd2\u540c\u5c5e\u4e8e\u51a0\u72b6\u75c5\u6bd2\u79d1\u3001\u51a0\u72b6\u75c5\u6bd2\u4e9a\u79d1\u3001\u03b2 \u51a0\u72b6\u75c5\u6bd2\u5c5e\u3001\u7c7b SARS \u51a0\u72b6\u75c5\u6bd2\u79cd\u3002<\/strong><\/span><\/p>\n


<\/span><\/p>\n

\"\u4e3a\u4ec0\u4e48\u4e0d\u80fd\u8bf4\u65b0\u578b\u51a0\u72b6\u75c5\u6bd2\u5c5e\u4e8e<\/section>\n

\u56fe\u6e90\uff1aInternational Committee on Nomenclature of Viruses<\/span><\/p>\n


<\/p>\n

\u4f46\u503c\u5f97\u4e00\u63d0\u7684\u662f\uff0c\u56fd\u9645\u75c5\u6bd2\u5206\u7c7b\u7cfb\u7edf\u4e5f\u63d0\u5230\uff0c\u6240\u8c13\u7684\u5206\u79cd\u5e76\u6ca1\u6709\u516c\u8ba4\u7684\u5206\u7c7b\u5b66\u610f\u4e49\uff0c\u4e0e\u6211\u4eec\u5e73\u65f6\u6240\u719f\u77e5\u7684\u300c\u7269\u79cd\u300d\u6982\u5ff5\u5e76\u4e0d\u76f8\u540c\u3002<\/span><\/p>\n


<\/span><\/p>\n

\u51c6\u786e\u6765\u8bf4\uff0c2019-nCoV \u5e94\u8be5\u662f\u4e00\u79cd SARS \u76f8\u5173\u51a0\u72b6\u75c5\u6bd2\u3002<\/span><\/strong><\/span><\/p>\n


<\/p>\n

\u5b83\u4fe9\u6709\u591a\u300c\u76f8\u5173\u300d\u5462\uff1f<\/span><\/strong><\/span><\/p>\n


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\u5168\u57fa\u56e0\u7ec4\u6c34\u5e73\u76f8\u4f3c\u6027\u7ea6 79%<\/span><\/strong><\/p>\n


<\/p>\n

\u6b64\u524d\u4e00\u7bc7\u300a\u67f3\u53f6\u5200\u300b\u7684\u6587\u7ae0\u5c06 2019-nCoV \u7684\u5b8c\u6574\u57fa\u56e0\u7ec4\u4e0e\u5df2\u77e5\u7684\u51a0\u72b6\u75c5\u6bd2\u57fa\u56e0\u7ec4\u5e93\u8fdb\u884c\u7eb5\u5411\u5bf9\u6bd4\u3002<\/span><\/p>\n


<\/p>\n

\"\u4e3a\u4ec0\u4e48\u4e0d\u80fd\u8bf4\u65b0\u578b\u51a0\u72b6\u75c5\u6bd2\u5c5e\u4e8e<\/section>\n

\u56fe\u6e90\uff1aThe Lancet<\/em><\/span><\/p>\n


<\/p>\n

\u7ed3\u679c\u53d1\u73b0\uff0c2019-nCoV \u4e0e\u4e24\u79cd 2018 \u5e74\u4e8e\u4e2d\u56fd\u821f\u5c71\u91c7\u96c6\u5230\u7684\u8759\u8760\u6765\u6e90 SARS \u6837\u51a0\u72b6\u75c5\u6bd2 bat-SL-CoVZC45 \u548c bat-SL-CoVZXC21 \u8f83\u4e3a\u76f8\u4f3c\u76f8\u5173\uff08\u76f8\u4f3c\u5ea6 88\uff05\uff09\uff0c\u4f46\u4e0e SARS-CoV\uff08\u76f8\u4f3c\u5ea6 79\uff05\uff09\u548c MERS-CoV<\/span>\uff08\u76f8\u4f3c\u5ea6 50\uff05\uff09\u76f8\u5dee\u8f83\u5927\u3002<\/span><\/p>\n


<\/p>\n

\"\u4e3a\u4ec0\u4e48\u4e0d\u80fd\u8bf4\u65b0\u578b\u51a0\u72b6\u75c5\u6bd2\u5c5e\u4e8e<\/section>\n
\u56fe\u6e90\uff1a<\/span>The Lancet<\/em><\/section>\n


<\/p>\n

\u6b66\u6c49\u75c5\u6bd2\u6240\u77f3\u6b63\u4e3d\u6559\u6388\u5728 Nature<\/em> \u53d1\u8868\u7684\u8bba\u6587 A pneumonia outbreak associated with a new coronavirus of probable bat origin \u8fdb\u4e00\u6b65\u63ed\u793a\u4e86 2019-nCoV \u4e0e SARS-CoV \u4e24\u4e2a\u51a0\u72b6\u75c5\u6bd2\u7684\u76f8\u4f3c\u6027\u3002<\/span><\/p>\n


<\/p>\n

\"\u4e3a\u4ec0\u4e48\u4e0d\u80fd\u8bf4\u65b0\u578b\u51a0\u72b6\u75c5\u6bd2\u5c5e\u4e8e<\/section>\n

\u56fe\u6e90\uff1aNature<\/em><\/span><\/p>\n


<\/p>\n

\u8be5\u7814\u7a76\u8868\u660e\uff0c2019-nCoV \u4e0e SARS-CoV \u57fa\u56e0\u7ec4\u6709 79.5% \u7684\u76f8\u4f3c\u6027\u3002\u6b64\u5916\uff0c\u7814\u7a76\u4eba\u5458\u8fd8\u53d1\u73b0\u8be5\u75c5\u6bd2\u5e8f\u5217\u4e0e\u4e00\u79cd\u4e91\u5357\u7684\u4e2d\u534e\u83ca\u5934\u8760\u7684\u51a0\u72b6\u75c5\u6bd2\u5728\u5168\u57fa\u56e0\u7ec4\u6c34\u5e73\u4e0a\u76f8\u4f3c\u5ea6\u9ad8\u8fbe 96%\uff0c\u8868\u660e\u8759\u8760\u53ef\u80fd\u662f 2019-nCoV<\/span> \u7684\u5bbf\u4e3b\u6765\u6e90\u3002<\/span><\/p>\n


<\/p>\n

\"\u4e3a\u4ec0\u4e48\u4e0d\u80fd\u8bf4\u65b0\u578b\u51a0\u72b6\u75c5\u6bd2\u5c5e\u4e8e<\/p>\n

\u56fe\u6e90\uff1a<\/span>Nature<\/em><\/span><\/p>\n


<\/span><\/p>\n

\u5c3d\u7ba1 <\/span>2019-nCov \u4e0e SARS-CoV\u76f8\u4f3c\u6027\u4ec5\u4e3a79.5%\uff0c\u76f8\u5dee\u8f83\u5927\uff0c<\/strong><\/span>\u4f46\u662f\u5728\u7528\u4e8e\u75c5\u6bd2\u9274\u522b\u7684 7 \u4e2a\u4fdd\u5b88\u57df\u4e0e SARS-CoV \u7684\u6c28\u57fa\u9178\u76f8\u4f3c\u6027\u9ad8\u8fbe 94.6%\uff0c\u8fdb\u4e00\u6b65\u63d0\u793a\u5176\u4e0e SARS-CoV \u5c5e\u4e8e\u540c\u4e00\u79cd\u5c5e\u3002<\/span><\/p>\n


<\/p>\n


<\/span><\/p>\n

2019-nCoV \u53ef\u901a\u8fc7 ACE2 \u53d7\u4f53\u611f\u67d3\u7ec6\u80de<\/span><\/strong><\/p>\n


<\/p>\n

\u53ef\u80fd\u8fd8\u6709\u4e00\u4e9b\u4eba\u4f1a\u6ce8\u610f\u5230\uff0c\u5728\u53d1\u5e03\u4f1a\u4e0a\u6709\u8fd9\u6837\u4e00\u53e5\u8bdd\u300c\u65b0\u578b\u51a0\u72b6\u75c5\u6bd2\u4f7f\u7528\u4e0e SARS \u51a0\u72b6\u75c5\u6bd2\u76f8\u540c\u7684\u7ec6\u80de\u8fdb\u5165\u53d7\u4f53<\/span>\u300d\uff0c\u600e\u4e48\u7406\u89e3\u5462\uff1f<\/span><\/p>\n


<\/span><\/p>\n

\u51a0\u72b6\u75c5\u6bd2\u901a\u8fc7 S \u86cb\u767d\u4e0e\u5bbf\u4e3b\u7684\u53d7\u4f53\u7ed3\u5408\uff0c\u4ece\u800c\u611f\u67d3\u5bbf\u4e3b\u7ec6\u80de\u3002\u51a0\u72b6\u75c5\u6bd2 S \u86cb\u767d\u7684\u591a\u6837\u6027\u9ad8\u3001\u673a\u5236\u590d\u6742\uff0c\u03b2 \u5c5e\u51a0\u72b6\u75c5\u6bd2\u7684 S \u86cb\u767d\u5927\u5c0f\u4ee5\u53ca\u5728\u7ec6\u80de\u8868\u9762\u4e0e\u5176\u7ed3\u5408\u7684\u53d7\u4f53\u90fd\u5404\u4e0d\u76f8\u540c\u3002<\/span><\/p>\n


<\/p>\n

\"\u4e3a\u4ec0\u4e48\u4e0d\u80fd\u8bf4\u65b0\u578b\u51a0\u72b6\u75c5\u6bd2\u5c5e\u4e8e<\/section>\n

\u4e00\u4e9b\u51a0\u72b6\u75c5\u6bd2\u7684\u53d7\u4f53\uff08\u56fe\u6e90\uff1aCoronaviruses\uff09<\/span><\/p>\n


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\u6b64\u524d\u4e00\u9879\u76f8\u5173\u7814\u7a76\u5bf9 2019-nCoV \u7684 S \u86cb\u767d\u8fdb\u884c\u4e86\u7ed3\u6784\u4e09\u7ef4\u5efa\u6a21\uff0c\u8bc4\u4f30\u4e86\u5176\u4e0e\u4eba\u7c7b ACE2 \u5206\u5b50\u76f8\u4e92\u4f5c\u7528\u7684\u80fd\u529b\u3002<\/span><\/p>\n


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\"\u4e3a\u4ec0\u4e48\u4e0d\u80fd\u8bf4\u65b0\u578b\u51a0\u72b6\u75c5\u6bd2\u5c5e\u4e8e<\/section>\n

\u56fe\u6e90\uff1a\u4e2d\u56fd\u79d1\u5b66<\/span><\/p>\n


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\u7ed3\u679c\u8868\u660e\uff0c\u5c3d\u7ba1\u5b58\u5728\u6c28\u57fa\u9178\u6b8b\u57fa\u7684\u66ff\u6362\uff0c\u4f46 2019-nCov \u7684 S \u86cb\u767d\u4e0e\u4eba ACE2 \u53d7\u4f53\u4ecd\u7136\u5177\u6709\u663e\u8457\u7684\u7ed3\u5408\u4eb2\u548c\u529b\u3002<\/span><\/p>\n


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\u77f3\u6b63\u4e3d\u7814\u7a76\u56e2\u961f\u8fdb\u4e00\u6b65<\/span>\u786e\u8bc1\u4e86<\/span> 2019-nCoV \u53ef\u4ee5\u901a\u8fc7\u7ec6\u80de\u819c\u8868\u9762 ACE2 \u53d7\u4f53\u8fdb\u5165\u7ec6\u80de\uff0c\u8fd9\u4e0e SARS-CoV \u8fdb\u5165\u7ec6\u80de\u7684\u9014\u5f84\u662f\u4e00\u6837\u7684\u3002<\/strong><\/span>\u800c\u8fd9\u4e5f\u4ece\u4e00\u65b9\u9762\u8bc1\u660e\u4e86 2019-nCoV \u4e0e SARS-CoV \u5728\u8d77\u6e90\u4e0a\u7684\u5bc6\u5207\u5173\u7cfb\uff0c\u540c\u5c5e\u4e8e SARS \u76f8\u5173\u51a0\u72b6\u75c5\u6bd2\u3002<\/span><\/p>\n


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\"\u4e3a\u4ec0\u4e48\u4e0d\u80fd\u8bf4\u65b0\u578b\u51a0\u72b6\u75c5\u6bd2\u5c5e\u4e8e<\/section>\n

\u56fe\u6e90\uff1a<\/span>Nature<\/em><\/span><\/p>\n


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\u7ed3\u8bed<\/strong><\/span><\/p>\n


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\u6700\u540e\u8ba9\u6211\u4eec\u603b\u7ed3\u4e00\u4e0b\uff0cSARS-CoV \u548c 2019-nCoV \u4e24\u4e2a\u75c5\u6bd2\u90fd\u5c5e\u4e8e \u03b2 \u5c5e\u51a0\u72b6\u75c5\u6bd2\uff0c\u4f46\u4e24\u8005\u5e76\u4e0d\u7b49\u540c\u3002<\/span><\/p>\n


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\u51c6\u786e\u6765\u8bf4\uff0c2019-nCoV \u5e94\u8be5\u662f\u4e00\u79cd SARS \u76f8\u5173\u51a0\u72b6\u75c5\u6bd2\uff0c\u4f46\u4e24\u8005\u5168\u57fa\u56e0\u7ec4\u6c34\u5e73\u76f8\u4f3c\u6027\u4ec5\u4e3a79.5%\uff0c\u76f8\u5dee\u8f83\u5927\u3002<\/span><\/p>\n


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2019-nCoV \u53ef\u4ee5\u901a\u8fc7\u7ec6\u80de\u8868\u9762 ACE2 \u53d7\u4f53\u8fdb\u5165\u7ec6\u80de\uff0c\u8fd9\u4e0e SARS-CoV \u8fdb\u5165\u7ec6\u80de\u7684\u9014\u5f84\u662f\u4e00\u6837\u7684\u3002<\/span><\/p>\n


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\u56e0\u6b64\uff0c2019-nCoV \u662f SARS \u76f8\u5173\u75c5\u6bd2\uff0c\u5b83\u548c SARS-CoV \u6709\u4e9b\u5173\u7cfb\uff0c\u4f46\u5b83\u662f\u4e00\u4e2a\u65b0\u7684\u75c5\u6bd2\uff0c\u6211\u4eec\u4e0d\u80fd\u8bf4\u5b83\u5c5e\u4e8e SARS \u75c5\u6bd2\u3002<\/span>\uff08\u8d23\u4efb\u7f16\u8f91\uff1agyouza\uff09<\/span><\/p>\n


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\u9898\u56fe\u6765\u6e90\uff1a\u4e2d\u56fd\u79d1\u5b66\u6280\u672f\u9986<\/span><\/p>\n

\u53c2\u8003\u6587\u732e\uff1a<\/span><\/section>\n
1. Fehr A R, Perlman S. Coronaviruses: an overview of their replication and pathogenesis[M]\/\/Coronaviruses. Humana Press, New York, NY, 2015: 1-23<\/span><\/section>\n
2.Xu X, Chen P, Wang J, et al. Evolution of the novel coronavirus from the ongoing Wuhan outbreak and modeling of its spike protein for risk of human transmission[J]. Science China Life Sciences, 2020: 1-4.<\/span>
<\/section>\n
3. Su S, Wong G, Shi W, et al. Epidemiology, genetic recombination, and pathogenesis of coronaviruses[J]. Trends in microbiology, 2016, 24(6): 490-502.<\/span>
<\/section>\n
4. Lu R, Zhao X, Li J, et al. Genomic characterisation and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding[J]. The Lancet, 2020.<\/span>
<\/section>\n
5. Zhou P, Yang X L, Wang X G, et al. A pneumonia outbreak associated with a new coronavirus of probable bat origin[J]. Nature, 2020: 1-4.<\/span>
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\u6700\u8fd1\u4e00\u6bb5\u65f6\u95f4\uff0c\u5927\u5bb6\u4e00\u76f4\u88ab\u65b0\u51a0\u75ab\u60c5\u7684\u65b0\u95fb\u7275\u52a8\u7740\u5fc3\u3002<\/span><\/p>\n


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\u4e3a\u4e86\u5e2e\u52a9\u5927\u5bb6\u66f4\u53ca\u65f6\u51c6\u786e\u5730\u4e86\u89e3\u75ab\u60c5\u4fe1\u606f\uff0c | \u4e01\u9999\u533b\u751f\u7279\u522b\u63a8\u51fa\u4e86\u300c\u5730\u533a\u75ab\u60c5\u8ba2\u9605\u300d<\/strong><\/span>\u7684\u670d\u52a1\uff01<\/span><\/p>\n


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\u6bcf\u4e2a\u4eba\u53ef\u4ee5\u8bbe\u7f6e\u81ea\u5df1\u5173\u5fc3\u7684\u5730\u533a\uff0c\u7cbe\u51c6\u8ba2\u9605\u5730\u533a\u75ab\u60c5\uff0c\u5f53\u8fd9\u4e2a\u5730\u533a\u6570\u636e\u60c5\u51b5\u6709\u66f4\u65b0\uff0c\u5373\u65f6\u4e3a\u4f60\u63a8\u9001\u6700\u65b0\u6d88\u606f\uff0c\u8ba9\u4f60\u4e0d\u9519\u8fc7\u4efb\u4f55\u91cd\u8981\u4fe1\u606f\u3002<\/strong><\/strong><\/span><\/p>\n


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\u6211\u4eec\u4fdd\u8bc1\uff1a<\/span><\/p>\n


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\u53ea\u91c7\u7eb3\u6743\u5a01\u4fe1\u6e90\uff0c<\/strong><\/span>\u5305\u62ec\uff1a\u4e2d\u56fd\u75be\u75c5\u9884\u9632\u63a7\u5236\u4e2d\u5fc3\u3001\u4eba\u6c11\u65e5\u62a5\u3001\u592e\u89c6\u65b0\u95fb\u4ee5\u53ca\u5404\u7701\u5e02\u5730\u65b9\u536b\u5065\u59d4\u7b49\u7b49\uff0c\u66f4\u4e0e\u4eba\u6c11\u65e5\u62a5\u8fbe\u6210\u6df1\u5ea6\u5408\u4f5c\u3002<\/strong><\/strong><\/span><\/p>\n


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\u4fe1\u606f\u53ca\u65f6\u51c6\u786e\uff0c<\/strong><\/span>\u6570\u636e\u5e08\u548c\u7f16\u8f91 24 \u5c0f\u65f6<\/strong>\u503c\u73ed\uff0c\u6301\u7eed\u540c\u6b65\u8ddf\u8e2a\u5b98\u65b9\u62ab\u9732\u7684\u6570\u636e\uff0c\u5b9e\u65f6\u5bf9\u6570\u636e\u4fe1\u606f\u8fdb\u884c\u7b5b\u9009\u7504\u522b\u3002<\/span><\/p>\n


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\u4f11\u606f\u65f6\u95f4\u4e0d\u6253\u6270\uff0c<\/strong><\/span>\u6bcf\u5929 23 \u70b9\u540e\u505c\u6b62\u63a8\u9001\uff0c\u5e76\u5728\u6b21\u65e5 7 \u70b9\u53d1\u51fa\u505c\u6b62\u63a8\u9001\u671f\u95f4\u7684\u603b\u4f53\u6570\u636e\u3002<\/span><\/p>\n


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\u7cbe\u51c6\u8ba2\u9605\uff0c\u5b9e\u65f6\u64ad\u62a5<\/span><\/p>\n

\u5feb\u901f\u83b7\u5f97\u75ab\u60c5\u8fdb\u5c55<\/span><\/p>\n

\u73b0\u5728\u5c31\u626b\u63cf\u6d77\u62a5\u4e8c\u7ef4\u7801<\/strong><\/strong><\/span><\/p>\n

\u5f00\u542f\u8ba2\u9605\u5427\uff01<\/span><\/p>\n


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\"\u4e3a\u4ec0\u4e48\u4e0d\u80fd\u8bf4\u65b0\u578b\u51a0\u72b6\u75c5\u6bd2\u5c5e\u4e8e<\/section>\n<\/section>\n<\/section>\n<\/section>\n
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\"\u4e3a\u4ec0\u4e48\u4e0d\u80fd\u8bf4\u65b0\u578b\u51a0\u72b6\u75c5\u6bd2\u5c5e\u4e8e<\/strong><\/strong><\/strong><\/strong><\/strong><\/strong><\/strong><\/section>\n<\/section>\n
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\u2193\u2193\u2193\u70b9\u51fb\u300c\u9605\u8bfb\u539f\u6587\u300d\u5f00\u542f\u300c\u75ab\u60c5\u8ba2\u9605\u300d<\/strong><\/span><\/p>\n<\/section>\n<\/section><\/div>\n","protected":false},"excerpt":{"rendered":"

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