{"id":134949,"date":"2020-03-08T02:39:30","date_gmt":"2020-04-21T03:36:58","guid":{"rendered":"http:\/\/www.05921.net\/index.php\/134949\/"},"modified":"2020-04-21T11:36:59","modified_gmt":"2020-04-21T03:36:59","slug":"093f2742a9","status":"publish","type":"post","link":"https:\/\/www.05921.net\/index.php\/134949\/","title":{"rendered":"\u5173\u7231\u5973\u6027 \u4ece\u300c\u5fc3\u300d\u8d77\u822a \u2014 \u5218\u6885\u6797\u6559\u6388\u7545\u8c08\u5973\u6027\u5fc3\u8840\u7ba1\u5065\u5eb7"},"content":{"rendered":"
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\"\u5173\u7231\u5973\u6027<\/section>\n<\/section>\n
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\u4fd7\u8bdd\u8bf4\uff0c\u5973\u4eba\u80fd\u9876\u534a\u8fb9\u5929\uff0c\u4f5c\u4e3a\u300c\u4e00\u5bb6\u4e4b\u4e3b\u300d\uff0c\u5973\u6027\u4eba\u7fa4\u627f\u62c5\u7740\u91cd\u8981\u7684\u5bb6\u5ead\u548c\u793e\u4f1a\u8d23\u4efb\u3002\u8fd1\u5e74\u6765\uff0c\u968f\u7740\u793e\u4f1a\u73af\u5883\u548c\u751f\u6d3b\u65b9\u5f0f\u7684\u53d8\u5316\uff0c\u8d8a\u6765\u8d8a\u591a\u7684\u5973\u6027\u4eba\u7fa4\u6b63\u5728\u906d\u53d7\u7740\u5404\u79cd\u75be\u75c5\u7684\u56f0\u6270\uff0c\u5176\u4e2d\u5fc3\u8840\u7ba1\u75be\u75c5\u66f4\u662f\u6210\u4e3a\u5a01\u80c1\u5973\u6027\u5065\u5eb7\u7684\u5934\u53f7\u6740\u624b\u3002<\/span><\/p>\n


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\u503c 2020 \u5e74\u300c\u56fd\u9645\u52b3\u52a8\u5987\u5973\u8282\u300d\u6765\u4e34\u4e4b\u9645\uff0c\u6211\u4eec\u6709\u5e78\u9080\u8bf7\u5230\u4e86\u4e2d\u534e\u533b\u5b66\u4f1a\u5fc3\u8840\u7ba1\u75c5\u5b66\u5206\u4f1a\u5973\u6027\u5fc3\u810f\u5065\u5eb7\u5b66\u7ec4\u7ec4\u957f\u3001\u4e2d\u56fd\u533b\u5e08\u534f\u4f1a\u5fc3\u8840\u7ba1\u5185\u79d1\u533b\u5e08\u5206\u4f1a\u5973\u533b\u5e08\u5de5\u4f5c\u59d4\u5458\u4f1a\u4e3b\u4efb\u59d4\u5458\u3001\u5317\u4eac\u5927\u5b66\u7b2c\u4e00\u533b\u9662\u8001\u5e74\u5185\u79d1\u4e3b\u4efb\u5218\u6885\u6797\u6559\u6388<\/strong>\uff0c\u4ece\u5973\u6027\u5fc3\u8840\u7ba1\u5065\u5eb7\u7ba1\u7406\u3001\u5973\u6027\u5fc3\u8870\u9632\u6cbb\u73b0\u72b6\u548c\u6cbb\u7597\u8fdb\u5c55\u7b49\u65b9\u9762\u5bf9\u5979\u8fdb\u884c\u4e86\u4e13\u8bbf\u3002<\/span><\/p>\n


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\"\u5173\u7231\u5973\u6027
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Q:<\/strong><\/section>\n<\/section>\n
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\u60a8\u4f5c\u4e3a\u4e2d\u534e\u533b\u5b66\u4f1a\u5fc3\u8840\u7ba1\u75c5\u5b66\u5206\u4f1a\u5973\u6027\u5fc3\u810f\u5065\u5eb7\u5b66\u7ec4\u7ec4\u957f\u53ca\u4e2d\u56fd\u533b\u5e08\u534f\u4f1a\u5fc3\u8840\u7ba1\u5185\u79d1\u533b\u5e08\u5206\u4f1a\u5973\u533b\u5e08\u5de5\u4f5c\u59d4\u5458\u4f1a\u4e3b\u4efb\u59d4\u5458\uff0c\u5bf9\u4e8e\u4fc3\u8fdb\u5973\u6027\u5fc3\u8840\u7ba1\u5065\u5eb7\u6709\u54ea\u4e9b\u60f3\u6cd5\u548c\u5de5\u4f5c\u89c4\u5212\uff1f<\/span><\/strong><\/span><\/p>\n<\/section>\n<\/section>\n

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A:<\/strong><\/section>\n<\/section>\n
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\u5fc3\u8840\u7ba1\u75c5\u662f\u5a01\u80c1\u6211\u56fd\u5973\u6027\u5065\u5eb7\u7684\u5934\u53f7\u6740\u624b [1]<\/sup>\uff0c\u4f46\u5c1a\u672a\u5f97\u5230\u533b\u52a1\u5de5\u4f5c\u8005\u548c\u516c\u4f17\u7684\u8db3\u591f\u91cd\u89c6\u3002\u5973\u6027\u5fc3\u8840\u7ba1\u75c5\u7684\u75c5\u7406\u751f\u7406\u5b66\u7279\u70b9\u3001\u4e34\u5e8a\u8868\u73b0\u3001\u75be\u75c5\u8bca\u65ad\u3001\u836f\u7269\u4ee3\u8c22\u548c\u9632\u6cbb\u7b56\u7565\u7b49\u5728\u67d0\u4e9b\u65b9\u9762\u6709\u522b\u4e8e\u7537\u6027\uff0c\u9700\u8981\u7279\u522b\u5173\u6ce8\u3002<\/span>\u5728\u6b64\u80cc\u666f\u4e4b\u4e0b\uff0c\u501f\u52a9\u4e8e\u4e2d\u534e\u533b\u5b66\u4f1a\u5fc3\u8840\u7ba1\u75c5\u5b66\u5206\u4f1a\u4e3b\u4efb\u59d4\u5458\u97e9\u96c5\u73b2\u9662\u58eb\u7b49\u5404\u7ea7\u9886\u5bfc\u7684\u652f\u6301\uff0c\u9488\u5bf9\u5973\u6027\u7684\u7279\u6b8a\u6027\uff0c\u8054\u5408\u672c\u9886\u57df\u7684\u4e13\u5bb6\u4eec\u5f00\u5c55\u4e86\u7cfb\u5217\u5de5\u4f5c\u3002<\/span><\/p>\n


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\u2460 \u5b8c\u6210\u64b0\u5199 \u300c\u5973\u6027\u6297\u6813\u6cbb\u7597\u4e2d\u56fd\u4e13\u5bb6\u5efa\u8bae\u300d\uff0c\u5373\u5c06\u542f\u52a8\u64b0\u5199\u300c\u5973\u6027\u5fc3\u529b\u8870\u7aed\u8bca\u6cbb\u4e2d\u56fd\u4e13\u5bb6\u5171\u8bc6\u300d\u3002<\/span><\/p>\n


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\u2461 \u7ee7\u7eed\u5728\u56fd\u5185\u5fc3\u8840\u7ba1\u4f1a\u8bae\u4e2d\u8bbe\u7acb\u5973\u6027\u5fc3\u8840\u7ba1\u8bba\u575b\u4e13\u573a\uff0c\u7814\u8ba8\u5973\u6027\u5fc3\u8840\u7ba1\u75be\u75c5\u76f8\u5173\u70ed\u70b9\u3001\u96be\u70b9\uff1b\u7ec4\u7ec7\u5fc3\u8840\u7ba1\u75c5\u5b66\u4e60\u73ed\u53ca\u4e34\u5e8a\u6280\u80fd\u57f9\u8bad\u73ed\uff1b\u5e2e\u6276\u57fa\u5c42\u533b\u9662\uff1b\u63d0\u9ad8\u4e34\u5e8a\u533b\u751f\u5bf9\u5973\u6027\u5fc3\u8840\u7ba1\u75c5\u7684\u8ba4\u8bc6\u3002<\/span><\/p>\n


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\u2462 \u7ee7\u7eed\u7ec4\u7ec7\u4e49\u8bca\u53ca\u793e\u4f1a\u516c\u76ca\u6d3b\u52a8\uff0c\u63d0\u9ad8\u516c\u4f17\u5bf9\u5973\u6027\u5fc3\u8840\u7ba1\u75c5\u53ca\u5176\u5371\u5bb3\u7684\u8ba4\u8bc6\u3002<\/span><\/p>\n


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Q:<\/strong><\/section>\n<\/section>\n
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\u8bf7\u60a8\u8c08\u8c08\u64b0\u5199\u300c\u5973\u6027\u5fc3\u529b\u8870\u7aed\u8bca\u6cbb\u4e2d\u56fd\u4e13\u5bb6\u5171\u8bc6\u300d\u7684\u521d\u8877<\/span><\/strong><\/span><\/p>\n<\/section>\n<\/section>\n

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A:<\/strong><\/section>\n<\/section>\n
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\u5fc3\u529b\u8870\u7aed\u662f\u4e00\u7c7b\u5a01\u80c1\u751f\u547d\u548c\u5f71\u54cd\u751f\u6d3b\u8d28\u91cf\u7684\u75be\u75c5\u3002\u4e0e\u7537\u6027\u76f8\u6bd4\uff0c\u5973\u6027\u5fc3\u8870\u60a3\u8005\u75be\u75c5\u7279\u70b9\u53ca\u836f\u7269\u7597\u6548\u5b58\u5728\u7279\u6b8a\u6027\u30022000 \u5e74\u4e2d\u56fd 35-74 \u5c81\u4eba\u7fa4\u4e2d\u6162\u6027\u5fc3\u529b\u8870\u7aed\u7684\u60a3\u75c5\u7387\u4e3a 0.9%\uff0c\u5973\u6027\u663e\u8457\u9ad8\u4e8e\u7537\u6027\uff081.0% vs 0.7%\uff09[2]<\/sup>\uff1b\u4e00\u9879\u4e2d\u56fd\u4e1c\u5317\u5730\u533a\u7684\u7814\u7a76\u663e\u793a [3]<\/sup>\uff1a\u5c04\u8840\u5206\u6570\u4fdd\u7559\u7684\u5fc3\u8870\uff08HFpEF\uff09\u60a3\u75c5\u7387\u968f\u5e74\u9f84\u589e\u957f\u800c\u589e\u52a0\uff0c\u5404\u5e74\u9f84\u7ec4\u5973\u6027\u53d1\u75c5\u7387\u5747\u9ad8\u4e8e\u7537\u6027 (p<\/em> < 0.05)\uff1bHFpEF \u603b\u4f53\u60a3\u75c5\u7387\u4e3a 3.5%(\u5973\u6027 4.9% vs \u7537\u6027 1.8%\uff0cp<\/em> < 0.01)\u3002<\/span><\/p>\n


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\u540c\u65f6\uff0c\u5973\u6027\u5fc3\u8870\u60a3\u8005\u66f4\u5bb9\u6613\u5408\u5e76\u623f\u98a4\u3001\u7cd6\u5c3f\u75c5\u3001\u9ad8\u8840\u538b\u3001\u8d2b\u8840\u3001\u7f3a\u94c1\u3001\u80be\u75c5\u3001\u5173\u8282\u708e\u3001\u865a\u5f31\u3001\u6291\u90c1\u548c\u7532\u72b6\u817a\u529f\u80fd\u5f02\u5e38\u7b49\u3002\u5fc3\u8870\u6cbb\u7597\u836f\u7269\u7684\u7597\u6548\u5b58\u5728\u6027\u522b\u5dee\u5f02\uff0c\u836f\u7269\u4e0d\u826f\u53cd\u5e94\u53d1\u751f\u7387\u5973\u6027\u662f\u7537\u6027\u7684 1.5-1.7 \u500d\u3002\u5e0c\u671b\u672c\u5171\u8bc6\u6709\u52a9\u4e8e\u4fc3\u8fdb\u5bf9\u5973\u6027\u5fc3\u8870\u7279\u6b8a\u6027\u7684\u8ba4\u8bc6\u53ca\u8bca\u6cbb\u89c4\u8303\u5316\uff0c\u63d0\u9ad8\u5973\u6027\u5fc3\u8870\u8bca\u6cbb\u6c34\u5e73\u3002<\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

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Q:<\/strong><\/section>\n<\/section>\n
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\u8bf7\u60a8\u8c08\u8c08\u6211\u56fd\u5973\u6027\u5fc3\u8870\u60a3\u8005\u7684\u9632\u6cbb\u73b0\u72b6\u53ca\u9762\u4e34\u7684\u6311\u6218\uff1f<\/span><\/strong><\/span><\/p>\n<\/section>\n<\/section>\n

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A:<\/strong><\/section>\n<\/section>\n
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\u9632\u6cbb\u73b0\u72b6<\/span><\/strong>\uff1a\u5bf9\u4e8e\u5c04\u8840\u5206\u6570\u964d\u4f4e\u7684\u5973\u6027\u5fc3\u8870\uff08HFrEF\uff09\u60a3\u8005\uff0c\u76ee\u524d\u6cbb\u7597\u7b56\u7565\u4e3a\u4ee5\u91d1\u4e09\u89d2 (\u8840\u7ba1\u7d27\u5f20\u7d20\u8f6c\u5316\u9176\u6291\u5236\u5242\uff08ACEI\uff09\/\u8840\u7ba1\u7d27\u5f20\u7d20\u2161\u53d7\u4f53\u963b\u6ede\u5242\uff08ARB\uff09\u3001\u03b2\u53d7\u4f53\u963b\u6ede\u5242\u548c\u919b\u56fa\u916e\u53d7\u4f53\u62ee\u6297\u5242) \u4e3a\u4e3b\u7684\u795e\u7ecf\u4f53\u6db2\u8c03\u8282\u3002\u5bf9\u4e8e\u5973\u6027 HFpEF \u60a3\u8005\uff0c\u6307\u5357\u63a8\u8350\u9488\u5bf9\u75c7\u72b6\u3001\u5e76\u5b58\u75be\u75c5\u53ca\u5371\u9669\u56e0\u7d20\uff0c\u91c7\u7528\u7efc\u5408\u6027\u6cbb\u7597\uff0c\u800c\u300c\u91d1\u4e09\u89d2\u300d\u5927\u89c4\u6a21\u5faa\u8bc1\u8bc1\u636e\u6709\u9650 [4]<\/sup>\u3002<\/span><\/p>\n


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\u6311\u6218<\/span><\/strong>\uff1a\u5973\u6027 HFpEF \u6bd4\u4f8b\u66f4\u9ad8\uff0c\u6765\u81ea\u6cd5\u56fd\u56fd\u5bb6\u4f4f\u9662\u6570\u636e\u5e93\u7684\u6570\u636e\u663e\u793a\u5973\u6027\u5fc3\u8870\u60a3\u8005\u7684\u5e73\u5747\u4f4f\u9662\u5929\u6570\u548c\u4f4f\u9662\u75c5\u6b7b\u7387\u5747\u660e\u663e\u9ad8\u4e8e\u7537\u6027\uff0c\u9664\u4e86\u63a7\u5236\u76f8\u5173\u5371\u9669\u56e0\u7d20\u5916\uff0c\u5bf9 HFpEF \u5e76\u65e0\u7406\u60f3\u7684\u6cbb\u7597\u836f\u7269 [5]<\/sup>\u3002\u6b64\u5916\uff0c\u5973\u6027\u5fc3\u8870\u60a3\u8005\u5bf9\u6307\u5357\u63a8\u8350\u6cbb\u7597\u7684\u4f9d\u4ece\u6027\u4e0d\u4f73\uff0c\u9700\u52a0\u5f3a\u6307\u5357\u5bf9\u4e34\u5e8a\u5de5\u4f5c\u89c4\u8303\u5316\u7684\u5f15\u9886\u3002<\/span><\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

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Q:<\/strong><\/section>\n<\/section>\n
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\u5728\u5fc3\u8870\u6cbb\u7597\u9886\u57df\uff0c\u8fd1\u671f\u6709\u4ec0\u4e48\u91cd\u8981\u7814\u7a76\uff1f<\/span>\u8fd9\u4e9b\u7814\u7a76\u5bf9\u5973\u6027\u5fc3\u8870\u60a3\u8005\u7684\u6cbb\u7597\u6709\u54ea\u4e9b\u542f\u793a\u610f\u4e49\uff1f<\/span><\/strong><\/p>\n<\/section>\n<\/section>\n

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A:<\/strong><\/section>\n<\/section>\n
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\u53c2\u8003\u6587\u732e\uff1a
[1]. \u4e2d\u56fd\u533b\u5e08\u534f\u4f1a\u5fc3\u8840\u7ba1\u5185\u79d1\u533b\u5e08\u5206\u4f1a\u5973\u533b\u5e08\u5de5\u4f5c\u59d4\u5458\u4f1a, \u4e2d\u534e\u533b\u5b66\u4f1a\u5fc3\u8840\u7ba1\u75c5\u5b66\u5206\u4f1a\u5973\u6027\u5fc3\u810f\u5065\u5eb7\u5b66\u7ec4. \u4e2d\u56fd\u5973\u6027\u5fc3\u8840\u7ba1\u75be\u75c5\u9884\u9632\u4e13\u5bb6\u5171\u8bc6 [J]. \u4e2d\u534e\u5185\u79d1\u6742\u5fd7, 2017(6).
[2]. \u4e2d\u56fd\u5fc3\u529b\u8870\u7aed\u6d41\u884c\u75c5\u5b66\u8c03\u67e5\u53ca\u5176\u60a3\u75c5\u7387 [J]. \u4e2d\u534e\u5fc3\u8840\u7ba1\u75c5\u6742\u5fd7, 2003(01):6-9.
[3]. Liang G , Xiaofan G , Ye C , et al. Prevalence and Risk Factors of Heart Failure with Preserved Ejection Fraction: A Population-Based Study in Northeast China[J]. International Journal of Environmental Research and Public Health, 2016, 13(8):770.
[4]. \u56fd\u5bb6\u536b\u751f\u8ba1\u751f\u59d4\u5408\u7406\u7528\u836f\u4e13\u5bb6\u59d4\u5458\u4f1a, \u4e2d\u56fd\u836f\u5e08\u534f\u4f1a, \u4e2d\u56fd\u836f\u5e08\u534f\u4f1a. \u5fc3\u529b\u8870\u7aed\u5408\u7406\u7528\u836f\u6307\u5357 [J]. \u4e2d\u56fd\u533b\u5b66\u524d\u6cbf\u6742\u5fd7\uff08\u7535\u5b50\u7248\uff09, 2016(8):66.
[5]. Am\u00e9lie, Gabet, Yves, et al. National trends in rate of patients hospitalized for heart failure and heart failure mortality in France, 2000\u20132012[J]. European Journal of Heart Failure, 2015.
[6]. Solomon SD, McMurray JJV, et al. Angiotensin-Neprilysin Inhibition in Heart Failure with Preserved Ejection Fraction [J]. N Engl J Med. 2019;381(17):1609-1620.
[7].<\/span>McMurray JJV, Jackson AM, et al. Effects of Sacubitril-Valsartan Versus Valsartan inWomen Compared With Men With Heart Failure and Preserved Ejection Fraction:Insights From PARAGON-HF [J]. Circulation. 2020 Feb 4;141(5):338-351.<\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n


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\u5f15\u8a00 \u4fd7\u8bdd\u8bf4\uff0c\u5973\u4eba\u80fd\u9876\u534a\u8fb9\u5929\uff0c\u4f5c\u4e3a\u300c\u4e00\u5bb6\u4e4b\u4e3b\u300d\uff0c\u5973\u6027\u4eba\u7fa4\u627f\u62c5\u7740\u91cd\u8981\u7684\u5bb6\u5ead\u548c\u793e\u4f1a\u8d23\u4efb\u3002\u8fd1\u5e74\u6765\uff0c\u968f\u7740\u793e\u4f1a\u73af\u5883\u548c\u751f\u6d3b […]<\/p>\n","protected":false},"author":1,"featured_media":134950,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[2],"tags":[],"_links":{"self":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/134949"}],"collection":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/comments?post=134949"}],"version-history":[{"count":1,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/134949\/revisions"}],"predecessor-version":[{"id":134955,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/134949\/revisions\/134955"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/media\/134950"}],"wp:attachment":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/media?parent=134949"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/categories?post=134949"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/tags?post=134949"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}