{"id":14562,"date":"2018-07-16T01:00:00","date_gmt":"2018-07-30T04:25:02","guid":{"rendered":"http:\/\/www.05921.net\/index.php\/2018\/07\/30\/%e3%80%90%e5%9f%b9%e4%bc%98%e3%80%91%e7%8e%af%e7%90%83%e5%8c%bb%e8%8d%af%e7%ae%80%e8%ae%af%e7%ac%ac66%e6%9c%9f\/"},"modified":"2018-07-30T12:25:03","modified_gmt":"2018-07-30T04:25:03","slug":"%e3%80%90%e5%9f%b9%e4%bc%98%e3%80%91%e7%8e%af%e7%90%83%e5%8c%bb%e8%8d%af%e7%ae%80%e8%ae%af%e7%ac%ac66%e6%9c%9f","status":"publish","type":"post","link":"https:\/\/www.05921.net\/index.php\/14562\/","title":{"rendered":"\u3010\u57f9\u4f18\u3011\u73af\u7403\u533b\u836f\u7b80\u8baf|\u7b2c66\u671f"},"content":{"rendered":"<div class=\"bpp-post-content\">\n<section class=\"xmteditor\" style=\"display:none;\"  ><\/section>\n<section class=\"\" style=\"white-space: normal;max-width: 100%;color: rgb(51, 51, 51);\">\n<section style=\"margin-top: 10px;max-width: 100%;box-sizing: border-box;text-align: center;word-wrap: break-word !important;\">\n<section  style=\"max-width: 100%;box-sizing: border-box;display: inline-block;vertical-align: bottom;width: 166.5px;border-width: 0px;word-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<section  style=\"max-width: 100%;box-sizing: border-box;vertical-align: middle;display: inline-block;width: 166.5px;word-wrap: break-word !important;overflow: hidden !important;\"><img class=\"\"      style=\"box-sizing: border-box;vertical-align: middle;word-wrap: break-word !important;visibility: visible !important;width: 166.5px !important;\" width=\"100%\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/07\/beepress2-1532924703.jpeg\" alt=\"\u3010\u57f9\u4f18\u3011\u73af\u7403\u533b\u836f\u7b80\u8baf|\u7b2c66\u671f\" title=\"\u3010\u57f9\u4f18\u3011\u73af\u7403\u533b\u836f\u7b80\u8baf|\u7b2c66\u671f\"><\/section>\n<\/section>\n<\/section>\n<\/section>\n<section  style=\"max-width: 100%;box-sizing: border-box;display: inline-block;vertical-align: bottom;width: 499.5px;border-bottom: 1px solid rgba(123, 161, 168, 0.498039);border-bottom-right-radius: 0px;word-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box;letter-spacing: 4px;font-size: 22px;color: rgb(62, 62, 62);word-wrap: break-word !important;\">\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 18px;box-sizing: border-box !important;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\">\u4f1a\u8bae\u901a\u77e5<\/strong><\/span><br style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\"  \/><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<p style=\"padding-right: 0.5em;padding-left: 0.5em;white-space: normal;max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><span style=\"max-width: 100%;color: rgb(62, 62, 62);box-sizing: border-box !important;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 14px;box-sizing: border-box !important;word-wrap: break-word !important;\">\u5efa\u7acbFDA\u8ba4\u53ef\u7684\u7814\u53d1\u548c\u751f\u4ea7\u6d41\u7a0b\u662f\u6210\u529f\u7684\u5173\u952e\u4e4b\u6240\u5728\uff0c\u800c\u719f\u6089\u7f8e\u56fd\u7684\u6cd5\u89c4\u548c\u6ce8\u518c\u6d41\u7a0b\u53ef\u4ee5\u8ba9\u6211\u4eec\u7684\u5de5\u4f5c\u4e8b\u534a\u529f\u500d\uff01\u672c\u6b21\u4f1a\u8bae\uff0c\u6211\u4eec\u5c06\u5bf9MAH\u5236\u5ea6\u3001\u6539\u826f\u521b\u65b0\u4e2d\u7f8e\u53cc\u62a5\u4f5c\u91cd\u70b9\u4ecb\u7ecd\uff0c\u5bf9\u60a8\u6240\u5173\u6ce8\u7684\u95ee\u9898\u8fdb\u884c\u91cd\u70b9\u89e3\u7b54\u3002\u671f\u5f85\u5e7f\u5927\u670b\u53cb\u7684\u5149\u4e34\u3002<\/span><\/strong><\/span><\/p>\n<p style=\"padding-right: 0.5em;padding-left: 0.5em;white-space: normal;max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><a href=\"https:\/\/mp.weixin.qq.com\/s?__biz=MzUyMTE1NTY4OA==&amp;mid=2247484167&amp;idx=1&amp;sn=2d57429860cabbf851d11a3b2a794e9f&amp;scene=21#wechat_redirect\" target=\"_blank\" style=\"max-width: 100%;text-decoration: underline;-webkit-tap-highlight-color: rgba(0, 0, 0, 0);outline: 0px;font-size: 15px;color: rgb(255, 169, 0);box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;text-decoration: underline;-webkit-tap-highlight-color: rgba(0, 0, 0, 0);outline: 0px;font-size: 15px;color: rgb(255, 169, 0);box-sizing: border-box !important;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\">\u4f1a\u8bae\u94fe\u63a5\uff1a<span style=\"color: rgb(255, 169, 0);text-decoration: underline;max-width: 100%;-webkit-tap-highlight-color: rgba(0, 0, 0, 0);outline: 0px;\">9\u67086\u65e5<\/span>-MAH\u5236\u5ea6\u89e3\u8bfb\u66a8\u6539\u826f\u521b\u65b0\u4e2d\u7f8e\u53cc\u62a5\u4ea7\u4e1a\u5bf9\u63a5\u7814\u8ba8\u4f1a\u9080\u8bf7\u51fd<\/strong><\/span><\/a><\/p>\n<section  class=\"_135editor\" style=\"white-space: normal;border-width: 0px;border-style: none;border-color: initial;\">\n<section style=\"padding: 10px;\">\n<section style=\"display: -webkit-flex;justify-content: flex-end;\">\n<section style=\"margin-right: -2px;margin-bottom: -30px;padding-left: 10px;width: 70px;background-color: rgb(254, 254, 254);\">\n<section  style=\"width: 70px;\"><img class=\"\"      style=\"width: 70px;display: block;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/07\/beepress4-1532924703.png\" alt=\"\u3010\u57f9\u4f18\u3011\u73af\u7403\u533b\u836f\u7b80\u8baf|\u7b2c66\u671f\" title=\"\u3010\u57f9\u4f18\u3011\u73af\u7403\u533b\u836f\u7b80\u8baf|\u7b2c66\u671f\"><\/section>\n<\/section>\n<\/section>\n<section style=\"padding: 15px 15px 30px;border-width: 2px;border-style: solid;border-color: rgb(178, 178, 178);border-radius: 5px;\">\n<section class=\"135brush\" style=\"margin-right: auto;margin-left: auto;line-height: 28px;color: rgb(153, 153, 153);word-break: break-word;text-align: justify;\">\n<p style=\"line-height: 2em;\"><span style=\"font-size: 15px;max-width: 100%;line-height: 22.5px;color: rgb(0, 0, 0);box-sizing: border-box !important;word-wrap: break-word !important;\"><\/span><span style=\"font-size: 16px;color: rgb(0, 0, 0);\">1\u3001<\/span><strong><span style=\"font-size: 16px;color: rgb(214, 168, 65);\">\u4e2d\u56fd\u53f0\u6e7e\u6d69\u9f0e\u751f\u6280<\/span><\/strong><span style=\"font-size: 16px;color: rgb(0, 0, 0);\">\u5ba3\u5e03\uff0c\u8be5\u516c\u53f8\u79ef\u6781\u7814\u53d1\u7684<\/span><strong><span style=\"font-size: 16px;color: rgb(0, 82, 255);\">\u6297\u764c\u65b0\u836fOBI-3424<\/span><\/strong><span style=\"font-size: 16px;color: rgb(0, 0, 0);\">\u83b7\u5f97\u7f8e\u56fdFDA\u9881\u53d1\u7684\u5b64\u513f\u836f\u8d44\u683c\uff0c\u7528\u4e8e\u6cbb\u7597\u809d\u7ec6\u80de\u764c\u3002\u503c\u5f97\u4e00\u63d0\u7684\u662f\uff0cOBI-3424\u662f\u4e00\u6b3efirst-in-class\u7684\u4ee5\u8fc7\u8868\u8fbe\u919b\u916e\u8fd8\u539f\u91761C3\u4e3a\u6807\u9776\u7684DNA\u70f7\u5316\u764c\u75c7\u6cbb\u7597\u836f\u7269\u3002<\/span><\/p>\n<p style=\"line-height: 2em;\"><span style=\"font-size: 16px;color: rgb(0, 0, 0);\"><br  \/><\/span><\/p>\n<p style=\"line-height: 2em;\"><span style=\"font-size: 16px;color: rgb(0, 0, 0);\">2\u3001<\/span><strong><span style=\"font-size: 16px;color: rgb(214, 168, 65);\">Aclaris Therapeutics<\/span><\/strong><span style=\"font-size: 16px;color: rgb(0, 0, 0);\">\u5ba3\u5e03\u79f0\uff0c\u7f8e\u56fdFDA\u5df2\u7ecf\u6388\u4e88\u516c\u53f8<\/span><strong><span style=\"font-size: 16px;color: rgb(0, 82, 255);\">\u5c40\u90e8\u6cbb\u7597\u7528JAK1\/3\u6291\u5236\u5242ATI-502<\/span><\/strong><span style=\"font-size: 16px;color: rgb(0, 0, 0);\">\u7528\u4e8e\u6591\u79c3\u6cbb\u7597\u7684\u5feb\u901f\u901a\u9053\u5730\u4f4d\uff0c\u5176\u4e2d\u5305\u62ec\u7528\u4e8e\u6591\u7247\u72b6\u6591\u79c3\u548c\u66f4\u4e25\u91cd\u7684\u53d8\u5f02\u578b\u75be\u75c5\u4ee5\u53ca\u5b8c\u5168\u8131\u53d1\u548c\u666e\u904d\u8131\u53d1\u7684\u6cbb\u7597\u3002<\/span><\/p>\n<p style=\"line-height: 2em;\"><span style=\"font-size: 16px;color: rgb(0, 0, 0);\"><br  \/><\/span><\/p>\n<p style=\"line-height: 2em;\"><span style=\"font-size: 16px;color: rgb(0, 0, 0);\">3\u3001<\/span><strong><span style=\"font-size: 16px;color: rgb(214, 168, 65);\">\u8fc8\u5170<\/span><\/strong><span style=\"font-size: 16px;color: rgb(0, 0, 0);\">\u5ba3\u5e03\u5728\u7f8e\u56fd\u63a8\u51fa\u8bfa\u534e\u65d7\u4e0b<\/span><strong><span style=\"font-size: 16px;color: rgb(0, 82, 255);\">\u827e\u65af\u80fd\u8d34\u7247\u7684\u4eff\u5236\u836f\u7269<\/span><\/strong><span style=\"font-size: 16px;color: rgb(0, 0, 0);\">\uff0c\u836f\u7269\u5242\u91cf\u5206\u522b\u4e3a4.6mg\/24\u5c0f\u65f6\uff0c9.5mg\/24\u5c0f\u65f6\u548c13.3mg\/24\u5c0f\u65f6\uff0c\u827e\u65af\u80fd\u8d34\u7247(\u5361\u5df4\u62c9\u6c40\u7ecf\u76ae\u7ed9\u836f\u7cfb\u7edf)\u7528\u4e8e\u6cbb\u7597\u8f7b\u81f3\u4e2d\u5ea6\u963f\u5c14\u8328\u6d77\u9ed8\u75c5\u3002<\/span><\/p>\n<p style=\"line-height: 2em;\"><span style=\"font-size: 16px;color: rgb(0, 0, 0);\"><br  \/><\/span><\/p>\n<p style=\"line-height: 2em;\"><span style=\"font-size: 16px;color: rgb(0, 0, 0);\">4\u3001<\/span><strong><span style=\"font-size: 16px;color: rgb(214, 168, 65);\">Enzyvant<\/span><\/strong><span style=\"font-size: 16px;color: rgb(0, 0, 0);\">\u5ba3\u5e03\uff0c\u5df2\u542f\u52a8\u5411\u7f8e\u56fdFDA\u63d0\u4ea4<\/span><strong><span style=\"font-size: 16px;color: rgb(0, 82, 255);\">RVT-802\u751f\u7269\u5236\u5242<\/span><\/strong><span style=\"font-size: 16px;color: rgb(0, 0, 0);\">\u8bb8\u53ef\u7533\u8bf7\u7684\u7a0b\u5e8f\u3002RVT-802\u662f\u4e00\u79cd\u5728\u7814\u7684\u57fa\u4e8e\u7ec4\u7ec7\u7684\u518d\u751f\u7597\u6cd5\uff0c\u65e8\u5728\u6cbb\u7597\u4e0e\u201c\u5b8c\u5168DiGeorge\u5f02\u5e38\u201d\u76f8\u5173\u7684\u5148\u5929\u6027\u65e0\u80f8\u817a\u5f15\u8d77\u7684\u539f\u53d1\u6027\u514d\u75ab\u7f3a\u9677\u3002<\/span><\/p>\n<p style=\"line-height: 2em;\"><span style=\"font-size: 16px;color: rgb(0, 0, 0);\"><br  \/><\/span><\/p>\n<p style=\"line-height: 2em;\"><span style=\"font-size: 16px;color: rgb(0, 0, 0);\">5\u3001<\/span><strong><span style=\"font-size: 16px;color: rgb(214, 168, 65);\">\u9ed8\u6c99\u4e1c<\/span><\/strong><span style=\"font-size: 16px;color: rgb(0, 0, 0);\">\u516c\u53f8\u5ba3\u5e03\u7f8e\u56fdFDA\u63a5\u53d7\u4e86\u8be5\u516c\u53f8\u4e3a<\/span><strong><span style=\"font-size: 16px;color: rgb(0, 82, 255);\">Keytruda<\/span><\/strong><span style=\"font-size: 16px;color: rgb(0, 0, 0);\">\u9012\u4ea4\u7684\u8865\u5145\u751f\u7269\u5236\u5242\u8bb8\u53ef\u7533\u8bf7\u5e76\u4e14\u6388\u4e88\u5176\u4f18\u5148\u5ba1\u8bc4\u8d44\u683c\u3002<\/span><\/p>\n<p style=\"line-height: 2em;\"><span style=\"font-size: 16px;color: rgb(0, 0, 0);\"><br  \/><\/span><\/p>\n<p style=\"line-height: 2em;\"><span style=\"font-size: 16px;color: rgb(0, 0, 0);\">6\u3001<\/span><strong><span style=\"font-size: 16px;color: rgb(214, 168, 65);\">BMS<\/span><\/strong><span style=\"font-size: 16px;color: rgb(0, 0, 0);\">\u5ba3\u5e03\uff0c\u7f8e\u56fdFDA\u5df2\u6279\u51c6<\/span><strong><span style=\"font-size: 16px;color: rgb(0, 82, 255);\">Opdivo\u8054\u5408\u4f4e\u5242\u91cfYervoy<\/span><\/strong><span style=\"font-size: 16px;color: rgb(0, 0, 0);\">\uff0c\u7528\u4e8e\u65e2\u5f80\u63a5\u53d73\u79cd\u6807\u51c6\u5316\u7597\u65b9\u6848\u540e\u75c5\u60c5\u8fdb\u5c55\u7684\u5fae\u536b\u661f\u4e0d\u7a33\u5b9a\u6027\u9ad8\u6216DNA\u9519\u914d\u4fee\u590d\u7f3a\u9677\u8f6c\u79fb\u6027\u7ed3\u76f4\u80a0\u764c\u513f\u79d1\u60a3\u8005\u548c\u6210\u4eba\u60a3\u8005\u7684\u6cbb\u7597\u3002<\/span><\/p>\n<p style=\"line-height: 2em;\"><span style=\"font-size: 16px;color: rgb(0, 0, 0);\"><br  \/><\/span><\/p>\n<p style=\"line-height: 2em;\"><span style=\"font-size: 16px;color: rgb(0, 0, 0);\">7\u3001<\/span><strong><span style=\"font-size: 16px;color: rgb(214, 168, 65);\">\u7f57\u6c0f\u65d7\u4e0b\u7684\u57fa\u56e0\u6cf0\u514b<\/span><\/strong><span style=\"font-size: 16px;color: rgb(0, 0, 0);\">\u5ba3\u5e03\u5411FDA\u63d0\u4ea4\u4e86\u5173\u4e8e<\/span><strong><span style=\"font-size: 16px;color: rgb(0, 82, 255);\">Venclexta\uff08venetoclax\uff09<\/span><\/strong><span style=\"font-size: 16px;color: rgb(0, 0, 0);\">\u7684\u8865\u5145\u65b0\u836f\u7533\u8bf7\u3002\u5982\u679c\u7533\u8bf7\u83b7\u6279\uff0cVenclexta\u53ef\u4e0e\u53bb\u7532\u57fa\u5316\u836f\u7269\u6216\u4f4e\u5242\u91cf\u963f\u7cd6\u80de\u82f7\u8054\u5408\u6cbb\u7597\u4e0d\u9002\u7528\u9ad8\u5242\u91cf\u5316\u7597\u7684\u6025\u6027\u9aa8\u9ad3\u6027\u767d\u8840\u75c5\u521d\u6cbb\u60a3\u8005\u3002<\/span><\/p>\n<\/section>\n<\/section>\n<section style=\"margin-top: -35px;margin-right: 10px;margin-left: 10px;padding-right: 8px;padding-left: 8px;width: 85px;background-color: rgb(254, 254, 254);\"><img class=\"\"      style=\"width: 85px;display: block;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/07\/beepress1-1532924703.png\" alt=\"\u3010\u57f9\u4f18\u3011\u73af\u7403\u533b\u836f\u7b80\u8baf|\u7b2c66\u671f\" title=\"\u3010\u57f9\u4f18\u3011\u73af\u7403\u533b\u836f\u7b80\u8baf|\u7b2c66\u671f\"><\/section>\n<\/section>\n<\/section>\n<p style=\"white-space: normal;text-align: left;\"><span style=\"color: rgb(136, 136, 136);font-family: \u5fae\u8f6f\u96c5\u9ed1;font-size: 12px;text-align: justify;text-indent: 24px;\">\u3010\u7f16\u8f91\uff1a\u5f20\u534e\u946b\u3011<\/span><img class=\"\"      src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/07\/beepress0-1532924703.jpg\" alt=\"\u3010\u57f9\u4f18\u3011\u73af\u7403\u533b\u836f\u7b80\u8baf|\u7b2c66\u671f\" title=\"\u3010\u57f9\u4f18\u3011\u73af\u7403\u533b\u836f\u7b80\u8baf|\u7b2c66\u671f\"><\/p>\n<section class=\"\"   style=\"white-space: normal;max-width: 100%;\">\n<section  style=\"max-width: 100%;width: 558px;box-sizing: border-box !important;word-wrap: break-word !important;\">\n<section style=\"margin: 10px auto;max-width: 100%;width: 280px;height: 110px;background-image: url('http:\/\/www.05921.net\/wp-content\/uploads\/2018\/07\/beepress7-1532924703.jpeg');background-repeat: no-repeat;background-size: 100%;overflow: hidden;box-sizing: border-box !important;word-wrap: break-word !important;\">\n<section style=\"margin-top: 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class='keep-source'>\n<p>\u59cb\u53d1\u4e8e\u5fae\u4fe1\u516c\u4f17\u53f7\uff1a                         \u57f9\u4f18\u521b\u65b0\u8bba\u575b                      <\/p>\n<\/blockquote>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>\u4f1a\u8bae\u901a\u77e5 \u5efa\u7acbFDA\u8ba4\u53ef\u7684\u7814\u53d1\u548c\u751f\u4ea7\u6d41\u7a0b\u662f\u6210\u529f\u7684\u5173\u952e\u4e4b\u6240\u5728\uff0c\u800c\u719f\u6089\u7f8e\u56fd\u7684\u6cd5\u89c4\u548c\u6ce8\u518c\u6d41\u7a0b\u53ef\u4ee5\u8ba9\u6211\u4eec\u7684\u5de5\u4f5c\u4e8b\u534a\u529f\u500d [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":14563,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[2],"tags":[],"_links":{"self":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/14562"}],"collection":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/comments?post=14562"}],"version-history":[{"count":1,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/14562\/revisions"}],"predecessor-version":[{"id":14569,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/14562\/revisions\/14569"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/media\/14563"}],"wp:attachment":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/media?parent=14562"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/categories?post=14562"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/tags?post=14562"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}