{"id":17845,"date":"2018-07-21T01:00:00","date_gmt":"2018-08-08T01:01:32","guid":{"rendered":"http:\/\/www.05921.net\/index.php\/2018\/08\/08\/%e8%81%94%e6%89%8b%ef%bc%81%e8%b4%9d%e8%be%be%e3%80%81%e5%90%9b%e5%ae%9e%e5%90%88%e4%bd%9c%e6%8e%a8%e5%87%ba%e5%85%8d%e7%96%ab%e7%bb%84%e5%90%88%e7%96%97%e6%b3%95-%e7%bb%bf%e5%8f%b6%e6%80%9d\/"},"modified":"2018-08-08T09:01:35","modified_gmt":"2018-08-08T01:01:35","slug":"%e8%81%94%e6%89%8b%ef%bc%81%e8%b4%9d%e8%be%be%e3%80%81%e5%90%9b%e5%ae%9e%e5%90%88%e4%bd%9c%e6%8e%a8%e5%87%ba%e5%85%8d%e7%96%ab%e7%bb%84%e5%90%88%e7%96%97%e6%b3%95-%e7%bb%bf%e5%8f%b6%e6%80%9d","status":"publish","type":"post","link":"https:\/\/www.05921.net\/index.php\/17845\/","title":{"rendered":"\u8054\u624b\uff01\u8d1d\u8fbe\u3001\u541b\u5b9e\u5408\u4f5c\u63a8\u51fa\u514d\u75ab\u7ec4\u5408\u7597\u6cd5 | \u7eff\u53f6\u601d\u745e\u5eb7\u7f13\u91ca\u7247\u65b0\u9002\u5e94\u75c7\u5728\u534e\u83b7\u6279…"},"content":{"rendered":"
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\u70b9\u51fb\u4e0a\u65b9\u7684 \u884c\u821fDrug <\/span>\u25b2 \u6dfb\u52a0\u5173\u6ce8<\/span><\/span><\/p>\n


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\u8054\u624b\uff01\u8d1d\u8fbe\u3001\u541b\u5b9e\u5408\u4f5c\u63a8\u51fa\u514d\u75ab\u7ec4\u5408\u7597\u6cd5<\/strong>\u3002\u8d1d\u8fbe\u836f\u4e1a\uff08300558\uff09\u516c\u544a\u79f0\uff0c\u5168\u8d44\u5b50\u516c\u53f8\u5361\u5357\u5409\u65b0\u836f Vorolanib<\/span>\uff08CM082\uff09\u548c\u541b\u5b9e\u751f\u7269\u65b0\u836f\u7279\u745e\u666e\u5229<\/span>\uff08JS001\uff09\u62df\u8054\u5408\u7528\u4e8e\u65e2\u5f80\u672a\u7ecf\u6cbb\u7597\u7684\u5c40\u90e8\u8fdb\u5c55\u6216\u8f6c\u79fb\u6027\u9ecf\u819c\u9ed1\u8272\u7d20\u7624<\/span>\u7684\u4e34\u5e8a\u8bd5\u9a8c\u7533\u8bf7\u5df2\u83b7\u56fd\u5bb6\u836f\u76d1\u5c40\u53d7\u7406\u3002CM082<\/span>\u662f\u9488\u5bf9VEGFR\u548cPDGFR\u9776\u70b9\u7684\u591a\u9776\u70b9\u53d7\u4f53\u916a\u6c28\u9178\u6fc0\u9176\uff08RTKs\uff09\u6291\u5236\u5242\u3002JS001<\/span>\u662f\u541b\u5b9e\u751f\u7269\u81ea\u4e3b\u7814\u53d1\u7684\u65b0\u578b\u91cd\u7ec4\u4eba\u6e90\u5316\u6297PD-1\u5355\u514b\u9686\u6297\u4f53\u3002CM082<\/span>\u4f5c\u4e3a\u6bd2\u526f\u4f5c\u7528\u8f83\u4f4e<\/span>\u7684\u9776\u5411\u836f\u7269\uff0c\u548cPD-1\u8054\u5408\u7684\u6cbb\u7597\u65b9\u6848\u503c\u5f97\u671f\u5f85\u3002\u4e2d\u56fd\u533a\u57df\u5185\u5c1a\u65e0\u514d\u75ab\u7597\u6cd5\u4e0e\u9776\u5411\u7597\u6cd5\u8054\u5408\u7684\u6cbb\u7597\u65b9\u6848\u83b7\u5f97\u56fd\u5bb6\u836f\u76d1\u5c40\u7684\u6279\u51c6\u4e0a\u5e02\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

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1. \u56fd\u5bb6\u836f\u76d1\u5c40\uff1a\u4fee\u8ba2\u8840\u585e\u901a\u6ce8\u5c04\u5242\u548c\u8840\u6813\u901a\u6ce8\u5c04\u5242\u8bf4\u660e\u4e66\u3002<\/strong>\u56fd\u5bb6\u836f\u76d1\u5c40\u53d1\u5e03\u516c\u544a\uff0c\u51b3\u5b9a\u5bf9<\/span>\u8840\u585e\u901a\u6ce8\u5c04\u5242<\/span>\u3014\u8840\u585e\u901a\u6ce8\u5c04\u6db2\u3001\u6ce8\u5c04\u7528\u8840\u585e\u901a\uff08\u51bb\u5e72\uff09\u3015\u548c\u8840\u6813\u901a\u6ce8\u5c04\u5242\u3014\u8840\u6813\u901a\u6ce8\u5c04\u6db2\u548c\u6ce8\u5c04\u7528\u8840\u6813\u901a\uff08\u51bb\u5e72\uff09\u3015\u589e\u52a0\u8b66\u793a\u8bed\uff0c\u5e76\u5bf9\u3010\u7981\u5fcc\u3011\u548c\u3010\u6ce8\u610f\u4e8b\u9879\u3011\u9879\u8fdb\u884c\u4fee\u8ba2\u3002\u3010\u7981\u5fcc\u3011\u9879\u4e0b\u660e\u786e<\/span>\u513f\u7ae5\u7981\u7528<\/span>\u3002\u3010\u6ce8\u610f\u4e8b\u9879\u3011\u9879\u5e94\u589e\u52a0\uff1a\u7981\u6b62\u8d85\u529f\u80fd\u4e3b\u6cbb\u8303\u56f4\u7528\u836f\u7b49\u3002<\/span><\/p>\n


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2. \u5b9a\u91cf\u8840\u6d41\u5206\u6570\u6d4b\u91cf\u7cfb\u7edf\u83b7\u6279\u4e0a\u5e02\u3002<\/strong>\u535a\u52a8\u533b\u5b66\u5f71\u50cf\u79d1\u6280\uff08\u4e0a\u6d77\uff09\u6709\u9650\u516c\u53f8\u7814\u5236\u7684\u521b\u65b0\u4ea7\u54c1 \u201c\u5b9a\u91cf\u8840\u6d41\u5206\u6570\u6d4b\u91cf\u7cfb\u7edf<\/span>\u201d \u83b7\u56fd\u5bb6\u836f\u76d1\u5c40\u6279\u51c6\u4e0a\u5e02<\/span>\u3002\u8be5\u4ea7\u54c1\u53ef\u65e0\u521b\u5730\u83b7\u5f97\u5b9a\u91cf\u8840\u6d41\u5206\u6570<\/span>\uff0c\u57fa\u4e8e\u6d41\u4f53\u529b\u5b66\u8ba1\u7b97\u5206\u6790\uff0c\u5229\u7528\u51a0\u72b6\u52a8\u8109\u9020\u5f71\u4e09\u7ef4\u91cd\u5efa\u7684\u7ed3\u679c\u548c\u5e73\u5747\u8840\u6d41\u901f\u5ea6\uff0c\u8ba1\u7b97\u8840\u7ba1\u6bcf\u4e2a\u4f4d\u7f6e\u4e0e\u6700\u8fd1\u7aef\u4f4d\u7f6e\u7684\u538b\u529b\u5dee\uff0c\u6c42\u89e3\u51fa\u76ee\u6807\u8840\u7ba1\u6bcf\u4e00\u4e2a\u4f4d\u7f6e\u7684\u5b9a\u91cf\u8840\u6d41\u5206\u6570\u3002<\/p>\n


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3. \u7eff\u53f6\u601d\u745e\u5eb7\u7f13\u91ca\u7247\u65b0\u9002\u5e94\u75c7\u5728\u534e\u83b7\u6279\u3002<\/strong>\u7eff\u53f6\u5236\u836f\u96c6\u56e2\u5ba3\u5e03\u5176\u4e2d\u67a2\u795e\u7ecf\u836f\u7269\u601d\u745e\u5eb7\u7f13\u91ca\u7247<\/span>\uff08\u5bcc\u9a6c\u9178\u55b9\u786b\u5e73\u7f13\u91ca\u7247\uff09\u7684\u65b0\u9002\u5e94\u75c7\u2014\u2014\u53cc\u76f8\u60c5\u611f\u969c\u788d\u7684\u6291\u90c1\u53d1\u4f5c<\/span>\uff0c\u5df2\u4e8e\u8fd1\u65e5\u6b63\u5f0f\u83b7\u5f97\u56fd\u5bb6\u836f\u76d1\u5c40\u7684\u6279\u51c6\u3002\u601d\u745e\u5eb7\u7f13\u91ca\u7247<\/span>\u662f\u5177\u6709\u6297\u6291\u90c1\u7279\u6027\u7684\u975e\u5178\u578b\u6297\u7cbe\u795e\u75c5\uff08AAP\uff09\u836f\u7269\uff0c\u4e3b\u8981\u7528\u4e8e\u6cbb\u7597\u7cbe\u795e\u5206\u88c2\u75c7\u548c\u53cc\u76f8\u60c5\u611f\u969c\u788d\u3002\u4eca\u5e74\u4e0a\u534a\u5e74\uff0c\u7eff\u53f6\u5236\u836f\u5411\u963f\u65af\u5229\u5eb7\u6536\u8d2d\u4e86\u601d\u745e\u5eb7\uff08\u5bcc\u9a6c\u9178\u55b9\u786b\u5e73\u7247\uff09\u53ca\u601d\u745e\u5eb7\u7f13\u91ca\u7247\u5728\u4e2d\u56fd\u7b4951\u4e2a<\/span>\u56fd\u5bb6\u548c\u5730\u533a\u7684\u4e1a\u52a1\uff0c\u76ee\u524d\u6536\u8d2d\u4e8b\u9879\u5df2\u5b8c\u6210\u3002<\/p>\n


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4. \u5929\u5883\u751f\u7269\u65b0\u836f\u83b7\u4e34\u5e8a\u8bd5\u9a8c\u8bb8\u53ef\u3002<\/strong>\u5929\u5883\u751f\u7269\u5ba3\u5e03\u5176\u5728\u7814\u65b0\u836fOlamkicept<\/span>\u5728\u4e2d\u56fd\u5883\u5185\u83b7\u5f97\u6e83\u75a1\u6027\u7ed3\u80a0\u708e<\/span>\uff08UC\uff09\u4e34\u5e8a\u8bd5\u9a8c\u8bb8\u53ef\u3002\u8be5\u8bd5\u9a8c\u662f\u4e00\u4e2a\u56fd\u9645\u591a\u4e2d\u5fc3\u7684II\u671f\u4e34\u5e8a\u7814\u7a76\uff0c\u4e8e2017\u5e74\u83b7\u97e9\u56fd\u3001\u6fb3\u5927\u5229\u4e9a\u548c\u53f0\u6e7e\u5730\u533a\u7684\u4e34\u5e8a\u8bd5\u9a8c\u8bb8\u53ef\u5e76\u5168\u9762\u542f\u52a8\uff0c\u4e14\u5df2\u89c2\u5bdf\u5230\u60a3\u8005\u83b7\u76ca\u3002\u4e24\u9879\u2160\u671f\u4e34\u5e8a\u8bd5\u9a8c\u8bc1\u5b9e\uff0cOlamkicept<\/span>\u5177\u6709\u5b89\u5168\u6027\u4f18\u52bf\u3002\u5fb7\u56fdII\u671f\u4e34\u5e8a\u8bd5\u9a8c\u8868\u660e\uff0cOlamkicept<\/span>\u5bf9\u6240\u6709\u6cbb\u7597\u65e0\u6548\u7684\u53d7\u8bd5\u8005\u4ecd\u5448\u73b0\u7ea628.6%<\/span>\u7684\u7f13\u89e3\u7387\u3002Olamkicept<\/span>\u7531\u6b27\u6d32FERRING\u516c\u53f8\u7814\u53d1\uff0c\u5929\u5883\u751f\u7269\u83b7\u5f97\u5176\u5728\u4e9a\u592a\u5730\u533a\u7684\u5f00\u53d1\u548c\u5546\u4e1a\u5316\u72ec\u5bb6\u6388\u6743\u3002 <\/p>\n


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5. \u4e0a\u6d77\u836f\u7269\u6240\u963f\u5c14\u8328\u6d77\u9ed8\u75c7\u65b0\u836f\u83b7\u6279\u8fdb\u5165\u4e34\u5e8a\u8bd5\u9a8c\u3002<\/strong>\u4e2d\u79d1\u9662\u4e0a\u6d77\u836f\u7269\u7814\u7a76\u6240\u7518\u52c7\u56e2\u961f\u548c\u7ae0\u6d77\u71d5\u56e2\u961f\u5171\u540c\u7814\u53d1\u7684\u6297\u963f\u5c14\u8328\u6d77\u9ed8\u6c0f\u75c7<\/span>2.2\u7c7b\u65b0\u836f\u77f3\u6749\u78b1\u7532\u63a7\u91ca\u7247<\/span>\uff08FN12\uff09\uff0c\u8fd1\u65e5\u83b7\u5f97\u56fd\u5bb6\u836f\u76d1\u5c40\u9881\u53d1\u7684\u300a\u836f\u7269\u4e34\u5e8a\u8bd5\u9a8c\u6279\u4ef6\u300b\uff0c\u83b7\u51c6\u8fdb\u5165\u4e34\u5e8a\u8bd5\u9a8c\u3002\u4e34\u5e8a\u524d\u836f\u4ee3\u3001\u836f\u6548\u3001\u6bd2\u7406\u7814\u7a76\u8bc1\u5b9e\uff0c\u8be5\u65b0\u5236\u5242\u80fd\u663e\u8457\u51cf\u5c11<\/span>\u77f3\u6749\u78b1\u7532\u539f\u836f\u7684\u7a81\u91ca\u6548\u5e94<\/span>\u3001\u7ef4\u6301\u836f\u7269\u5e73\u7a33\u91ca\u653e\uff0c\u5e76\u663e\u8457\u5ef6\u957f\u836f\u7269\u836f\u6548\u7ef4\u6301\u65f6\u95f4\uff0c\u51cf\u5c11\u5916\u5468\u80c6\u78b1\u80fd\u526f\u53cd\u5e94\u3002<\/p>\n


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6. \u5eb7\u5e0c\u8bfa\u751f\u7269\u8d74\u6e2f\u4e0a\u5e02\u3002<\/strong>\u5eb7\u5e0c\u8bfa\u751f\u7269\u80a1\u4efd\u516c\u53f8\u5411\u6e2f\u4ea4\u6240\u9012\u4ea4\u62db\u80a1\u8bf4\u660e\u4e66\uff0c\u6210\u4e3a\u6b4c\u793c\u3001\u534e\u9886\u3001\u76df\u79d1\u3001\u4fe1\u8fbe\u3001\u65b9\u8fbe\u3001Stealth BioTherapeutics Corp\u53caAOBiome Therapeutics,Inc.\u4e4b\u540e\u7b2c\u516b\u5bb6<\/span>\u7533\u8bf7\u6e2f\u4ea4\u6240\u4e0a\u5e02<\/span>\u4e14\u672a\u6709\u6536\u5165<\/span>\u7684\u751f\u7269\u79d1\u6280\u4f01\u4e1a\u3002\u5eb7\u5e0c\u8bfa\u662f\u4e00\u5bb6\u75ab\u82d7\u7814\u53d1\u4f01\u4e1a\uff0c\u4e3b\u8981\u7814\u53d1\u5168\u7403\u521b\u65b0\u3001\u56fd\u5185\u9996\u521b\u548c\u56fd\u5185\u6700\u4f73\u7684\u4e09\u4e2a\u75ab\u82d7\u7c7b\u522b\uff0c\u76ee\u524d\u6b63\u572812\u4e2a\u75be\u75c5\u9886\u57df\u7814\u53d115\u79cd\u75ab\u82d7\u3002\u5176\u4e2d\uff0c\u8111\u819c\u708e\u7403\u83cc\u7ed3\u5408\u75ab\u82d7\u4e8c\u4ef7MCV\uff08MCV2\uff09\u548c\u56db\u4ef7MCV\uff08MCV4\uff09\u9884\u8ba1\u5206\u522b\u4e8e2018\u5e74\u5e74\u5e95\u524d\u548c2019\u5e74\u63d0\u4ea4\u65b0\u836f\u7533\u8bf7\uff1b\u800c\u5176\u57c3\u535a\u62c9\u75ab\u82d7<\/span>\u7684\u65b0\u836f\u6ce8\u518c\u7533\u8bf7\u5df2\u83b7\u6279\u51c6\u3002<\/p>\n


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7. \u836f\u660e\u751f\u7269\u3001\u6d77\u5229\u751f\u7269\u5408\u4f5c\u5e03\u5c40\u4eba\u7528\u75ab\u82d7CDMO\u4e1a\u52a1\u3002<\/strong>7\u670818\u65e5\uff0c\u836f\u660e\u751f\u7269\uff0802269.HK\uff09\u5ba3\u5e03\uff0c\u4e0e\u6d77\u5229\u751f\u7269\uff08603718.SH\uff09\u8ba2\u7acb\u5408\u8d44\u4f01\u4e1a\u534f\u8bae\uff0c\u4ee5\u6210\u7acb\u5408\u8d44\u4f01\u4e1a\u3002\u5408\u8d44\u4f01\u4e1a\u5c06\u4e3b\u8981\u4ece\u4e8b\u4eba\u7528\u75ab\u82d7<\/span>\uff08\u5305\u62ec\u764c\u75c7\u75ab\u82d7\uff09CDMO\uff08\u5408\u540c\u5b9a\u5236\u7814\u53d1\u751f\u4ea7\uff09\u4e1a\u52a1\uff0c\u5e76\u63d0\u4f9b\u4eba\u7528\u75ab\u82d7\u4ece\u6982\u5ff5\u5230\u5546\u4e1a\u5316\u751f\u4ea7\u5168\u8fc7\u7a0b\u7684\u53d1\u73b0\u3001\u5f00\u53d1\u53ca\u751f\u4ea7\u7aef\u5230\u7aef\u670d\u52a1\u53ca\u89e3\u51b3\u65b9\u6848\u5e73\u53f0\u3002\u6839\u636e\u53cc\u65b9\u534f\u8bae\uff0c\u5408\u8d44\u4f01\u4e1a\u6210\u7acb\u540e\uff0c\u836f\u660e\u751f\u7269\u53ca\u6d77\u5229\u751f\u7269\u5206\u522b\u62e5\u670970%<\/span>\u53ca30%<\/span>\u80a1\u6743\uff0c\u5408\u8d44\u4f01\u4e1a\u7684\u6ce8\u518c\u8d44\u672c\u603b\u989d\u62df\u5b9a\u4e3a\u4eba\u6c11\u5e015\u4ebf\u5143<\/span>\u3002<\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

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1. \u8bfa\u534e\u4e73\u817a\u764c\u836fKisqali\u65b0\u9002\u5e94\u75c7\u7533\u8bf7\u83b7FDA\u6279\u51c6\u3002<\/strong>\u8bfa\u534e\uff08Novartis\uff09\u7684<\/span>Kisqali<\/span>\uff08ribociclib\uff09\u83b7FDA\u6279\u51c6\uff0c\u4e0e<\/span>\u82b3\u9999\u9176\u6291\u5236\u5242<\/span>\uff08aromatase inhibitor\uff0c AI\uff09\u8054\u5408\uff0c\u4f5c\u4e3a\u521d\u59cb\u5185\u5206\u6ccc\u6cbb\u7597\uff0c\u7528\u4e8e\u7f79\u60a3\u6fc0\u7d20\u53d7\u4f53\uff08HR\uff09\u9633\u6027\u3001\u4eba\u8868\u76ae\u751f\u957f\u56e0\u5b50\u53d7\u4f532\uff08HER2\uff09\u9634\u6027\u665a\u671f\u6216\u8f6c\u79fb\u6027<\/span>\u4e73\u817a\u764c<\/span>\u7684<\/span>\u7edd\u7ecf\u524d\u6216\u540e\u5973\u6027<\/span>\u3002\u6b64\u5916\uff0cFDA\u8fd8\u6279\u51c6<\/span>Kisqali<\/span>\u4e0e\u6c1f\u7ef4\u53f8\u7fa4\uff08fulvestrant\uff09\u8054\u5408\u4f5c\u4e3a\u521d\u59cb\u5185\u5206\u6ccc\u6cbb\u7597\u6216\u75be\u75c5\u8fdb\u5c55\u540e\u5185\u5206\u6ccc\u6cbb\u7597\uff0c\u7528\u4e8e\u7f79\u60a3HR\u9633\u6027\u3001HER2\u9634\u6027\u665a\u671f\u6216\u8f6c\u79fb\u6027\u4e73\u817a\u764c\u7684\u7edd\u7ecf\u540e\u5973\u6027\u3002<\/span>Kisqali<\/span>\u662f\u4e00\u79cd\u9009\u62e9\u6027\u7ec6\u80de\u5468\u671f\u86cb\u767d\u4f9d\u8d56\u6027\u6fc0\u9176\u6291\u5236\u5242\u3002<\/span><\/p>\n


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2. Immunomedics\u9996\u4e2a\u6297\u4f53\u5076\u8054\u836f\u7269\u83b7FDA\u4f18\u5148\u5ba1\u8bc4\u8ba4\u5b9a\u3002<\/strong>Immunomedics\u516c\u53f8\u5ba3\u5e03\uff0c<\/span>sa<\/span>cituzumab govitecan<\/span>\u7684\u751f\u7269\u5236\u54c1\u4e0a\u5e02\u7533\u8bf7\uff08BLA\uff09\u83b7FDA\u6388\u4e88\u4f18\u5148\u5ba1\u8bc4\u8ba4\u5b9a\uff0c\u7528\u4e8e\u6b64\u524d\u81f3\u5c11\u63a5\u53d7\u4e24\u6b21\u6cbb\u7597\u7684<\/span>\u8f6c\u79fb\u6027\u4e09\u9634\u6027\u4e73\u817a\u764c<\/span>\uff08mTNBC\uff09\uff0c\u9884\u8ba1PDUFA\u65e5\u671f\u5b9a\u57282019\u5e741\u670818\u65e5\u3002\u2160\/\u2161\u671f\u4e34\u5e8a\u7814\u7a76\u6570\u636e\u663e\u793a\uff0c110\u4f8b\u63a5\u53d7<\/span>sacituzumab govitecan<\/span>\uff08IMMU-132\uff09\u6cbb\u7597\u7684\u60a3\u8005\u5176\u5ba2\u89c2\u7f13\u89e3\u7387\uff08ORR\uff09\u8fbe<\/span>34%<\/span>\uff0837\/110\uff09\uff0c\u5176\u4e2d3\u4f8b\u4e3a\u5b8c\u5168\u7f13\u89e3\uff08CR\uff09\uff0c34\u4f8b\u4e3a\u90e8\u5206\u7f13\u89e3\uff08PR\uff09\u3002\u4e34\u5e8a\u83b7\u76ca\u7387\uff08CBR\uff1aCR+PR+SD\uff1e6\u4e2a\u6708\uff09\u4e3a<\/span>46%<\/span>\u3002<\/span>Sacituzumab govitecan<\/span>\u662f<\/span>\u4e00\u6b3efirst-in-class ADC\u836f\u7269\uff0c\u7531\u6297TROP-2\u5355\u6297\u548c\u7ec6\u80de\u6bd2SN-38\u7ec4\u6210\u3002<\/span><\/p>\n


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3. \u536b\u6750\u51cf\u80a5\u836fCAMELLIA-TIMI 61\u7814\u7a76\u7ed3\u679c\u79ef\u6781\u3002<\/strong>\u536b\u6750\uff08Eisai\uff09\u516c\u5e03\u5176\u51cf\u80a5\u836f<\/span>BELVIQ\u00ae<\/span>\uff08\u6c2f\u5361\u8272\u6797\u76d0\u9178\u76d0\uff0c\u53c8\u540dVENESPRI\u00ae\uff09\u7684CAMELLIA-TIMI 61\u5fc3\u8840\u7ba1\u5f71\u54cd\u8bd5\u9a8c\u7684\u79ef\u6781\u9876\u7ebf\u7ed3\u679c\u3002CAMELLIA-TIMI 61\u7814\u7a76\u662fFDA\u5bf9BELVIQ\u00ae<\/span>\u4e0a\u5e02\u540e\u8981\u6c42\u7684\u4e00\u90e8\u5206\uff0c\u4e3b\u8981\u76ee\u7684\u662f\u8bc4\u4f30\u5176\u957f\u671f<\/span>\u5fc3\u8840\u7ba1\u5b89\u5168\u6027<\/span>\uff0c\u5e76\u8bc4\u4f30\u5728\u60a3\u6709\u5fc3\u8840\u7ba1\u75be\u75c5\u6216\u60a3\u6709\u5fc3\u8840\u7ba1\u9ad8\u5371\u76842\u578b\u7cd6\u5c3f\u75c5\uff08T2DM\uff09\u7684\u8d85\u91cd\u6216\u80a5\u80d6\u7684\u6210\u5e74\u4eba\u4e2d\uff0c\u4e3b\u8981\u4e0d\u826f\u5fc3\u8840\u7ba1\u4e8b\u4ef6\uff08MACE\uff09\u7684\u53d1\u751f\u7387\u3002\u7ed3\u679c\u8868\u660e\uff0c\u8be5\u7814\u7a76\u8fbe\u5230\u5176\u4e3b\u8981\u5b89\u5168\u6027\u7ec8\u70b9\uff0c\u5373\u4f7f\u7528BELVIQ\u00ae<\/span>\u957f\u671f\u6cbb\u7597\u4e0d\u4f1a\u589e\u52a0MACE\u7684\u53d1\u751f\u7387\u3002 <\/span><\/p>\n


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4. \u6b66 \u7530 \u63d0 \u4ea4 \u80a0 \u9053 \u9009 \u62e9 \u6027 \u65b0 \u578b \u6297 \u708e \u836f \u65b0 \u9002 \u5e94 \u75c7 \u7533 \u8bf7\u3002<\/strong>\u6b66\u7530\uff08Takeda\uff09\u5ba3\u5e03\uff0c\u5df2\u5411\u65e5\u672c\u52b3\u52a8\u536b\u751f\u798f\u5229\u90e8\uff08MHLW\uff09\u63d0\u4ea4\u65b0\u578b\u6297\u708e\u836f<\/span>Entyvio<\/span>\uff08vedolizumab\uff09\u6cbb\u7597\u4e2d\u91cd\u5ea6<\/span>\u6297\u6d3b<\/span>\u52a8\u6027\u514b\u7f57\u6069\u75c5<\/span>\uff08CD\uff09\u6210\u4eba\u60a3\u8005\u7684\u65b0\u9002\u5e94\u75c7\u7533\u8bf7\u3002\u800c\u4e8e\u672c\u6708\u521d\uff0c<\/span>Entyvio<\/span>\u5df2\u83b7MHLW\u6279\u51c6\u7528\u4e8e\u4e2d\u91cd\u5ea6\u6e83\u75a1\u6027\u7ed3\u80a0\u708e\uff08UC\uff09\u6210\u4eba\u60a3\u8005\u7684\u6cbb\u7597\u3002Entyvio\u662f\u4e00\u79cd\u80a0\u9053\u9009\u62e9\u6027\u4eba\u6e90\u5316\u5355\u514b\u9686\u6297\u4f53\uff0c\u4e8e2014\u5e745\u6708\u83b7\u7f8e\u56fd\u548c\u6b27\u76df\u6279\u51c6\u4e0a\u5e02\u3002\u76ee\u524d\uff0c<\/span>Entyvio<\/span>\u5df2\u83b7\u5168\u740360\u591a\u4e2a\u56fd\u5bb6\u6279\u51c6\u3002<\/span><\/p>\n


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5. \u8f89\u745e\/\u793c\u6765\u5173\u8282\u708e\u75bc\u75db\u7ba1\u7406\u65b0\u836f\u8fbe\u6240\u6709\u2162\u671f\u7ec8\u70b9\u3002<\/strong>\u8f89\u745e\uff08Pfizer\uff09\u548c\u793c\u6765\uff08Eli Lilly\uff09\u5171\u540c\u5ba3\u5e03\uff0c\u5176\u5728\u7814\u6b62\u75db\u836f<\/span>tanezumab<\/span>\u5728\u7528\u4e8e<\/span>\u9aa8\u6027\u5173\u8282\u708e<\/span>\uff08OA\uff09<\/span>\u75bc\u75db\u7ba1\u7406<\/span>\u7684\u2162\u671f\u8bd5\u9a8c\u4e2d\uff0c\u8fbe\u5230\u6240\u67093\u9879\u8bd5\u9a8c\u7ec8\u70b9\uff0c\u5e76\u663e\u793a\u51fa\u826f\u597d\u7684\u8010\u53d7\u6027\uff0c\u4ec5\u6709<\/span>1%<\/span>\u7684\u60a3\u8005\u56e0\u526f\u4f5c\u7528\u7ec8\u6b62\u8bd5\u9a8c\uff0c\u6cbb\u7597\u7ec4\u6709\u5c11\u4e8e1.5%\u7684\u60a3\u8005\u53d1\u751fOA\u5feb\u901f\u8fdb\u5c55\u3002<\/span>Tanezumab<\/span>\u662f\u4e00\u79cd\u4eba\u6e90\u5355\u514b\u9686\u6297\u4f53\u836f\u7269\uff0c\u53ef\u4ee5\u9009\u62e9\u6027\u7ed3\u5408\u5e76\u6291\u5236\u795e\u7ecf\u751f\u957f\u56e0\u5b50\uff08NGF\uff09\uff0c\u662f\u7b2c\u4e00\u4e2a\u5f97\u5230FDA\u5feb\u901f\u901a\u9053\u8d44\u683c\u7684NGF\u6291\u5236\u5242\u3002<\/span><\/p>\n


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6. Neuraly\u83b73600\u4e07\u7f8e\u5143A\u8f6e\u878d\u8d44\u3002<\/strong>Neuraly\u5ba3\u5e03\u5b8c\u6210<\/span>3600\u4e07\u7f8e\u5143<\/span>\u7684A\u8f6e\u878d\u8d44\uff0c\u7531 D\uff06D Pharmatech\u9886\u6295\uff0c Smilegate Investment\u3001InterVest\u3001LB Investment\u7b49\u53c2\u6295\u3002\u540c\u65f6\uff0cNeuraly\u8fd8\u5ba3\u5e03\uff0c\u5c06\u4e3b\u8981\u5f00\u53d1\u7528\u4e8e\u795e\u7ecf\u9000\u884c\u6027\u75be\u75c5\u5982\u5e15\u91d1\u68ee\u75c5\u548c\u963f\u5179\u6d77\u9ed8\u75c5\u7684\u6cbb\u7597\u836f<\/span>NLY01<\/span>\uff0c\u5e76\u9884\u8ba1\u57282018\u5e74\u5f00\u59cb\u8be5\u836f\u7684\u2160\u671f\u4e34\u5e8a\u8bd5\u9a8c\u3002\u6b64\u8f6e\u878d\u8d44\u4e5f\u5c06\u52a0\u901f\u8be5\u7814\u7a76\u6210\u679c\u7684\u8f6c\u5316\uff0c\u63a8\u8fdbNLY01\u9879\u76ee\u8fdb\u5165\u4e34\u5e8a\u3002<\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

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\u533b\u836f\u70ed\u70b9<\/strong><\/span><\/span><\/strong><\/span><\/strong><\/span><\/p>\n<\/section>\n

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1. \u201c\u4e2d\u56fd\u513f\u7ae5\u6807\u51c6\u8111\u7ed3\u6784\u6a21\u677f\u201d \u5b8c\u6210\u521d\u6b65\u7ed8\u5236\u3002<\/strong>\u8fd1\u65e5\uff0c\u4e2d\u56fd\u513f\u7ae5\u9752\u5c11\u5e74\u8111\u667a\u7814\u7a76\u5168\u56fd\u8054\u76df\u201d \u901a\u8fc7\u91c7\u96c6\u6765\u81ea\u5355\u4e2a\u7814\u7a76\u4e2d\u5fc3\u7684328\u4f8b6\u81f312\u5c81\u5065\u5eb7\u513f\u7ae5\u7684\u9ad8\u8d28\u91cf\u78c1\u5171\u632f\u8111\u7ed3\u6784\u5f71\u50cf\u6570\u636e\uff0c\u518d\u7ecf\u8fc7\u7cbe\u7ec6\u7684\u8111\u56fe\u50cf\u5206\u5272\u548c\u914d\u51c6\u7b97\u6cd5\uff0c\u751f\u6210\u4e86\u4ee51\u5c81\u4e3a\u5e74\u9f84\u95f4\u9694\u7684\u4e09\u7ef4\u7acb\u4f53\u8111\u53d1\u80b2\u6a21\u677f\uff0c\u521d\u6b65\u7ed8\u5236\u4e86<\/span>\u4e2d\u56fd\u5b66\u9f84\u513f\u7ae5\u6807\u51c6\u8111\u7ed3\u6784\u6a21\u677f\u96c6<\/span>\uff0c\u4e3a\u7814\u7a76\u5e76\u63ed\u793a\u6211\u56fd\u513f\u7ae5\u8111\u7ed3\u6784\u548c\u8111\u529f\u80fd\u53d1\u80b2\u89c4\u5f8b\u5960\u5b9a\u57fa\u7840\u3002<\/span><\/p>\n


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2. \u7814\u7a76\u53d1\u73b0\u8fc7\u654f\u6027\u9f3b\u708e\u7684\u65b0\u81f4\u75c5\u57fa\u56e0\u3002<\/strong>\u5fb7\u56fd\u4ea5\u59c6\u970d\u5179\u6155\u5c3c\u9ed1\u7814\u7a76\u4e2d\u5fc3\u9886\u8854\u7684\u56fd\u9645\u7814\u7a76\u56e2\u961f\u5728\u6536\u96c6\u4e86\u8fd1\uff19\uff10\u4e07\u4eba\u7684\u6570\u636e\uff0c\u5e76\u5bf9\u4e0e<\/span>\u8fc7\u654f\u6027\u9f3b\u708e<\/span>\u6709\u5173\u7684\u98ce\u9669\u57fa\u56e0\u8fdb\u884c\u62c9\u7f51\u5f0f\u641c\u7d22\u540e\u53d1\u73b0\uff0c<\/span>\uff12\uff10\u4e2a<\/span>\u4e0e\u8fc7\u654f\u6027\u9f3b\u708e\u6709\u5173\u7684\u65b0\u98ce\u9669\u57fa\u56e0\uff0c\u8fd9\u6709\u671b\u4e3a\u8fc7\u654f\u6027\u9f3b\u708e\u7684\u9632\u6cbb\u627e\u5230\u65b0\u76ee\u6807\u3002\u76f8\u5173\u7814\u7a76\u6210\u679c\u53d1\u8868\u5728\u65b0\u4e00\u671f\u82f1\u56fd\u300a\u81ea\u7136\u00b7\u9057\u4f20\u5b66\u300b\u6742\u5fd7\u4e0a\u3002<\/span><\/p>\n


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3. \u786b\u7cd6\u94dd\u6709\u671b\u6cbb\u7597\u7cd6\u5c3f\u75c5\u3002<\/strong>\u8fd1\u65e5\uff0c\u82f1\u56fd\u300a\u81ea\u7136\u6750\u6599\u300b\u6742\u5fd7\u520a\u767b\u7684\u7f8e\u56fd\u54c8\u4f5b\u5927\u5b66\u4e00\u9879\u65b0\u7814\u7a76\u53d1\u73b0\uff0c\u4e00\u79cd\u6cbb\u7597<\/span>\u80c3\u6e83\u75a1<\/span>\u7684\u8001\u836f<\/span>\u786b\u7cd6\u94dd<\/span>\u4e5f\u53ef\u4ee5\u7528\u4e8e\u6cbb\u7597<\/span>\u7cd6\u5c3f\u75c5<\/span>\uff0c\u5e76\u4e3a<\/span>\u80a5\u80d6\u75c7<\/span>\u7684\u6cbb\u7597\u63d0\u4f9b\u4e86\u4e00\u6761\u65b0\u9014\u5f84\u3002<\/span><\/p>\n


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4. \u767d\u8840\u75c5\u6216\u80fd\u901a\u8fc7\u65b0\u8def\u5f84\u6269\u6563\u81f3\u5927\u8111\u3002<\/strong>\u7f8e\u56fd\u79d1\u5b66\u5bb6\u56e2\u961f\u901a\u8fc7\u7814\u7a76\u8bc1\u5b9e\uff0c\u6025\u6027\u6dcb\u5df4\u7ec6\u80de\u767d\u8840\u75c5\uff08ALL\uff09\u7ec6\u80de\u4f1a\u968f\u7740<\/span>\u8170\u690e<\/span>\u6216<\/span>\u9885\u9aa8\u9aa8\u9ad3<\/span>\u4e0e<\/span>\u86db\u7f51\u819c\u4e0b\u8154<\/span>\u4e4b\u95f4<\/span>\u8840\u7ba1\u8fc1\u79fb<\/span>\u3002\u800c\u5728\u6b64\u8fc7\u7a0b\u4e2d\uff0c \u6025\u6027\u6dcb\u5df4\u7ec6\u80de\u767d\u8840\u75c5\u7ec6\u80de\u8868\u8fbe\u7684\u6574\u5408\u7d20\uff0c\u4f1a\u4ecb\u5bfc\u764c\u7ec6\u80de\u548c\u8fd9\u4e9b\u8840\u7ba1\u7684\u57fa\u5e95\u819c\u76f8\u7ed3\u5408\uff0c\u800c\u5e72\u9884\u8fd9\u79cd\u7ed3\u5408\u53ef\u4ee5\u51cf\u5c11\u8111\u8f6c\u79fb\u7684\u53d1\u751f\u3002\u56e0\u6b64\uff0c\u5f04\u6e05\u6b63\u5e38\u8840\u7ec6\u80de\u548c\u764c\u7ec6\u80de\u4e0e\u8840\u7ba1\u4e4b\u95f4\u7684\u76f8\u4e92\u4f5c\u7528\u6709\u52a9\u4e8e\u53d1\u73b0\u66f4\u591a\u7684\u5e72\u9884\u9776\u70b9\uff0c\u4ece\u800c\u6cbb\u7597\u4e2d\u67a2\u795e\u7ecf\u7cfb\u7edf\u7684\u764c\u7ec6\u80de\u6d78\u6da6\u3002 <\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

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\u80a1\u5e02\u8d44\u8baf<\/strong><\/span><\/span><\/strong><\/span><\/strong><\/span><\/p>\n<\/section>\n

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\u4e0a\u4e2a\u4ea4\u6613\u65e5 A \u80a1\u533b\u836f\u677f\u5757 <\/span><\/span> <\/span><\/span>-1.52%<\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/p>\n

\u6da8\u5e45\u524d\u4e09    \u8dcc\u5e45\u524d\u4e09<\/span><\/p>\n

\u8fe6\u5357\u79d1\u6280 <\/span><\/span><\/span>+10.02%  <\/span><\/span>\u4e30\u539f\u836f\u4e1a<\/span> <\/span><\/span><\/span><\/span><\/span><\/span>-7.22%<\/span><\/span><\/p>\n

\u5929\u76ee\u836f\u4e1a<\/span> <\/span><\/span><\/span><\/span><\/span><\/span>+10.02%  <\/span><\/span><\/span><\/span><\/span><\/span><\/span>\u667a\u98de\u751f\u7269<\/span><\/span> <\/span><\/span><\/span><\/span><\/span><\/span>-6.16%<\/span><\/span><\/p>\n

\u7ea2\u65e5\u836f\u4e1a <\/span><\/span><\/span><\/span><\/span><\/span>+3.99<\/span>%   <\/span><\/span><\/span><\/span>\u6c49\u68ee\u5236\u836f<\/span> <\/span><\/span><\/span>-5.66%<\/span><\/span><\/p>\n

\n

\u3010\u8d1d\u8fbe\u836f\u4e1a\u3011\u5361\u5357\u5409\u65b0\u836fVorolanib\uff08CM082\uff09\u548c\u541b\u5b9e\u751f\u7269\u65b0\u836f\u7279\u745e\u666e\u5229\uff08JS001\uff09\u62df\u8054\u5408\u7528\u4e8e\u65e2\u5f80\u672a\u7ecf\u6cbb\u7597\u7684\u5c40\u90e8\u8fdb\u5c55\u6216\u8f6c\u79fb\u6027\u9ecf\u819c\u9ed1\u8272\u7d20\u7624\u7684\u836f\u54c1\u4e34\u5e8a\u8bd5\u9a8c\u7533\u8bf7\u5df2\u83b7\u5f97\u56fd\u5bb6\u836f\u76d1\u5c40\u53d7\u7406\u3002<\/p>\n


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\u3010\u6d77\u601d\u79d1\u3011\u6c1f\u54cc\u567b\u5428\u7f8e\u5229\u66f2\u8f9b\u7247\u901a\u8fc7\u836f\u54c1\u4e00\u81f4\u6027\u8bc4\u4ef7\u3002<\/p>\n


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\u3010\u672a\u540d\u533b\u836f\u3011\u5168\u8d44\u5b50\u516c\u53f8\u672a\u540d\u751f\u7269\u533b\u836f\u7684\u6ce8\u5c04\u7528\u9f20\u795e\u7ecf\u751f\u957f\u56e0\u5b50\u83b7\u5f97\u836f\u7269\u4e34\u5e8a\u8bd5\u9a8c\u6279\u4ef6\u3002<\/p>\n


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\u3010\u4e9a\u5b9d\u836f\u4e1a\u3011\u6536\u5230\u56fd\u5bb6\u836f\u76d1\u5c40\u6838\u51c6\u7b7e\u53d1\u7684\u6ce8\u5c04\u7528SY-007\u300a\u836f\u7269\u4e34\u5e8a\u8bd5\u9a8c\u6279\u4ef6\u300b\u3002<\/p>\n


<\/p>\n

\u3010\u534e\u6d77\u836f\u4e1a\u3011\u7ecf\u4e0eFDA\u6c9f\u901a\uff0c\u516c\u53f8\u51b3\u5b9a\u5bf9\u5728\u7f8e\u56fd\u4e0a\u5e02\u7684\u7f2c\u6c99\u5766\u5236\u5242\u4ea7\u54c1\u4ece\u6d88\u8d39\u8005\u5c42\u9762\u8fdb\u884c\u4e3b\u52a8\u53ec\u56de\uff0c\u56e0\u6b64\u4ea7\u751f\u7684\u635f\u5931\u9700\u89c6\u5ba2\u6237\u5b58\u91cf\u6570\u636e\u53ca\u6d88\u8d39\u8005\u9000\u56de\u7684\u6570\u91cf\u800c\u5b9a\uff1b\u540c\u65f6\uff0c\u516c\u53f8\u4e3b\u52a8\u6682\u505c\u7f8e\u56fd\u5e02\u573a\u7684\u4f9b\u5e94\u3002<\/p>\n


<\/p>\n

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<\/p>\n

\u3010\u827e\u5fb7\u751f\u7269\u3011\u516c\u53f8\u4e8e2015\u5e746\u67085\u65e5\u7533\u8bf7\u7684\u201c\u4e00\u79cdFFPE\u6837\u672c\u7684FISH\u9884\u5904\u7406\u65b9\u6cd5\u4ee5\u53ca\u9884\u5904\u7406\u6db2\u201d\u53d1\u660e\u4e13\u5229\u83b7\u5f97\u4e2d\u534e\u4eba\u6c11\u5171\u548c\u56fd\u56fd\u5bb6\u77e5\u8bc6\u4ea7\u6743\u5c40\u9881\u53d1\u7684\u53d1\u660e\u4e13\u5229\u8bc1\u4e66\u3002<\/p>\n


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\u5ba1\u8bc4\u52a8\u5411<\/strong><\/span><\/p>\n<\/section>\n

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1. CDE\u6700\u65b0\u53d7\u7406\u60c5\u51b5\uff087\u670819\u65e5\uff09<\/strong><\/p>\n

\"\u8054\u624b\uff01\u8d1d\u8fbe\u3001\u541b\u5b9e\u5408\u4f5c\u63a8\u51fa\u514d\u75ab\u7ec4\u5408\u7597\u6cd5<\/p>\n


<\/p>\n

2. FDA\u6700\u65b0\u83b7\u6279\u60c5\u51b5\uff08\u5317\u7f8e7\u670817\u65e5\uff09<\/strong><\/p>\n

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\u6587\u7ae0\u4fe1\u606f\u6e90<\/span><\/span>\u4e8e\u516c<\/span>\u4f17\u53f7\u836f\u7814\u53d1<\/span>\uff0c<\/span>\u767b\u8f7d\u8be5\u6587\u7ae0\u76ee\u7684\u4e3a\u66f4\u5e7f\u6cdb\u7684\u4f20\u9012\u884c\u4e1a\u4fe1\u606f\uff0c\u4e0d\u4ee3\u8868\u8d5e\u540c\u5176\u89c2\u70b9\u6216\u5bf9\u5176\u771f\u5b9e\u6027\u8d1f\u8d23\u3002\u6587\u7ae0\u7248\u6743\u5f52\u539f\u4f5c\u8005\u53ca\u539f\u51fa\u5904\u6240\u6709\uff0c\u6587\u7ae0\u5185\u5bb9\u4ec5\u4f9b\u53c2\u8003\u3002\u672c\u7f51\u62e5\u6709\u5bf9\u6b64\u58f0\u660e\u7684\u6700\u7ec8\u89e3\u91ca\u6743\uff0c\u82e5\u65e0\u610f\u4fb5\u72af\u7248\u6743\uff0c\u8bf7\u8054\u7cfb\u5c0f\u7f16\u5220\u9664\u3002<\/span><\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n

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\u5b66\u5982\u9006\u6c34\u884c\u821f\uff0c\u4e0d\u8fdb\u5219\u9000\uff1b<\/span><\/p>\n

\u5fc3\u4f3c\u5e73\u539f\u8d70\u9a6c\uff0c\u6613\u653e\u96be\u6536\u3002<\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n

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\u884c\u821fDrug<\/span><\/p>\n<\/section>\n

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\u6bcf\u65e5\u66f4\u65b0 \u6b22\u8fce\u8ba2\u9605+<\/span><\/p>\n

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<\/p>\n

\"\u8054\u624b\uff01\u8d1d\u8fbe\u3001\u541b\u5b9e\u5408\u4f5c\u63a8\u51fa\u514d\u75ab\u7ec4\u5408\u7597\u6cd5<\/p>\n<\/section>\n


<\/p>\n

\u533b\u836f\u5927\u6570\u636e|\u884c\u4e1a\u52a8\u6001|\u653f\u7b56\u89e3\u8bfb<\/span><\/p>\n


<\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

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\u59cb\u53d1\u4e8e\u5fae\u4fe1\u516c\u4f17\u53f7\uff1a \u884c\u821fDrug <\/p>\n<\/blockquote>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

\u70b9\u51fb\u4e0a\u65b9\u7684 \u884c\u821fDrug \u25b2 \u6dfb\u52a0\u5173\u6ce8 \u4eca\u65e5\u5934\u6761 \u8054\u624b\uff01\u8d1d\u8fbe\u3001\u541b\u5b9e\u5408\u4f5c\u63a8\u51fa\u514d\u75ab\u7ec4 […]<\/p>\n","protected":false},"author":1,"featured_media":17846,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[2],"tags":[],"_links":{"self":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/17845"}],"collection":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/comments?post=17845"}],"version-history":[{"count":1,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/17845\/revisions"}],"predecessor-version":[{"id":17854,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/17845\/revisions\/17854"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/media\/17846"}],"wp:attachment":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/media?parent=17845"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/categories?post=17845"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/tags?post=17845"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}