{"id":20074,"date":"2018-07-16T01:00:00","date_gmt":"2018-08-08T01:16:32","guid":{"rendered":"http:\/\/www.05921.net\/index.php\/2018\/08\/08\/%e8%8d%af%e5%ad%a6%e7%a0%94%e7%a9%b6%e6%96%87%e7%8c%ae%e6%a3%80%e7%b4%a2%e7%bb%8f%e9%aa%8c%e5%88%86%e4%ba%ab\/"},"modified":"2018-08-08T09:16:35","modified_gmt":"2018-08-08T01:16:35","slug":"%e8%8d%af%e5%ad%a6%e7%a0%94%e7%a9%b6%e6%96%87%e7%8c%ae%e6%a3%80%e7%b4%a2%e7%bb%8f%e9%aa%8c%e5%88%86%e4%ba%ab","status":"publish","type":"post","link":"https:\/\/www.05921.net\/index.php\/20074\/","title":{"rendered":"\u836f\u5b66\u7814\u7a76\u6587\u732e\u68c0\u7d22\u7ecf\u9a8c\u5206\u4eab"},"content":{"rendered":"
\n

\u5c0f\u7f16\u89c9\u5f97\u4f5c\u4e3a\u836f\u5b66\u7814\u7a76\u8005\uff0c\u65e5\u5e38\u9700\u8981\u548c\u63a5\u89e6\u7684\u6587\u732e\u4e3b\u8981\u5206\u4e09\u79cd\uff1a<\/span><\/span><\/p>\n

\n
\n
\"\u836f\u5b66\u7814\u7a76\u6587\u732e\u68c0\u7d22\u7ecf\u9a8c\u5206\u4eab\"<\/section>\n

01<\/span><\/p>\n

\u548c\u67d0\u5177\u4f53\u54c1\u79cd\u76f8\u5173\u7684\u6587\u732e\uff0c\u5982\u6307\u793a\u7a33\u5b9a\u6027\u5206\u6790\u65b9\u6cd5\u7684\u5f00\u53d1\u7684\u3001\u7a33\u5b9a\u6027\u76f8\u5173\u7684\u3001\u5904\u65b9\u5f00\u53d1\u7684\u3001\u6676\u578b\u76f8\u5173\u7684\u7b49\uff0c\u8be5\u7c7b\u53c2\u8003\u6587\u732e\u53ef\u4ee5\u4e3a\u6211\u4eec\u7684\u7814\u53d1\u5de5\u4f5c\u63d0\u4f9b\u76f4\u63a5\u7684\u53c2\u8003\u4fe1\u606f\uff0c\u5408\u7406\u7684\u5e94\u7528\u5b9a\u4f1a\u8fbe\u5230\u4e8b\u534a\u529f\u500d\u7684\u6548\u679c\uff1b<\/span><\/p>\n

\n
<\/section>\n<\/section>\n<\/section>\n<\/section>\n
\n
\n
\"\u836f\u5b66\u7814\u7a76\u6587\u732e\u68c0\u7d22\u7ecf\u9a8c\u5206\u4eab\"<\/section>\n

02<\/span><\/p>\n

\u7efc\u8ff0\u7c7b\u6587\u7ae0\uff0c\u4e3b\u8981\u805a\u7126\u67d0\u4e00\u65b9\u9762\u95ee\u9898\u8fdb\u884c\u7cfb\u7edf\u7684\u8bba\u8ff0\uff0c\u5982\u6742\u8d28\u8c31\u7814\u7a76\u7b56\u7565\u7684\u3001\u6676\u578b\u7814\u7a76\u76f8\u5173\u7684\u3001<\/span>USP IV<\/span>\u6cd5\u6eb6\u51fa\u4eea\u5e94\u7528\u76f8\u5173\u7684\u7b49\uff0c\u8be5\u7c7b\u6587\u732e\u901a\u8fc7\u6982\u5ff5\u89e3\u6790\u3001\u7406\u8bba\u9610\u8ff0\u53ca\u6848\u4f8b\u5206\u6790\u7b49\uff0c\u7531\u6d45\u5165\u6df1\u7684\u6784\u5efa\u51fa\u67d0\u9886\u57df\u7684\u8f6e\u5ed3\uff0c\u662f\u5feb\u901f\u8865\u5145\u76f8\u5173\u77e5\u8bc6\u9996\u9009\u8d44\u6599\uff1b<\/span><\/span><\/p>\n

\n
<\/section>\n<\/section>\n<\/section>\n<\/section>\n
\n
\n
\"\u836f\u5b66\u7814\u7a76\u6587\u732e\u68c0\u7d22\u7ecf\u9a8c\u5206\u4eab\"<\/section>\n

03<\/span><\/p>\n

\u6307\u5357\u7c7b\u53ca\u4e13\u4e1a\u4e66\u7c4d\u7c7b\uff0c\u901a\u8fc7\u66f4\u52a0\u7cfb\u7edf\u7684\u8bba\u8ff0\uff0c\u5e2e\u52a9\u6784\u5efa\u8d77\u7cfb\u7edf\u624e\u5b9e\u7684\u4e13\u4e1a\u57fa\u7840\uff0c\u662f\u6269\u5c55\u4e13\u4e1a\u8ba4\u77e5\u548c\u63d0\u5347\u4e13\u4e1a\u6c34\u5e73\u5fc5\u4e0d\u53ef\u5c11\u7684\u5de5\u5177\u3002<\/span><\/p>\n

\n
<\/section>\n<\/section>\n<\/section>\n<\/section>\n


<\/span><\/span><\/p>\n

\u4f46\u662f\uff0c\u7531\u4e8e\u6743\u9650\u9650\u5236\uff0c\u8fd9\u4e9b\u6587\u732e\u548c\u4e66\u7c4d\u5e76\u4e0d\u662f\u90a3\u4e48\u5bb9\u6613\u83b7\u5f97\u3002\u5c24\u5176\u662f\u5728\u4f01\u4e1a\u5de5\u4f5c\uff0c\u5f88\u5c11\u6709\u8d2d\u4e70\u5404\u5927\u6570\u636e\u5e93\u8d26\u53f7\u7684\uff0c\u5c31\u7b97\u6709\u4e5f\u662f\u638c\u63e1\u5728\u67d0\u4e9b\u9886\u5bfc\u624b\u4e2d\u3002\u56e0\u6b64\uff0c\u5982\u4f55\u68c0\u7d22\u548c\u4e0b\u8f7d\u6587\u732e\uff0c\u4e5f\u6210\u4e86\u4e00\u95e8<\/span>\u201c\u624b\u827a\u6d3b\u201d\u3002\u4e0b\u9762\u5c0f\u7f16\u5c31\u548c\u5927\u5bb6\u5206\u4eab\u4e00\u4e0b\u4e2a\u4eba\u603b\u7ed3\u7684\u6587\u732e\u68c0\u7d22\u548c\u4e0b\u8f7d\u7684\u7ecf\u9a8c\uff0c\u4ee5\u671f\u80fd\u7ed9\u5927\u5bb6\u5e26\u53bb\u5e2e\u52a9\u3002<\/span> <\/span><\/p>\n

<\/span><\/p>\n


<\/p>\n

\n
\"\u836f\u5b66\u7814\u7a76\u6587\u732e\u68c0\u7d22\u7ecf\u9a8c\u5206\u4eab\"<\/section>\n
\u82f1\u6587\u671f\u520a\u6587\u732e\u7684\u68c0\u7d22\u4e0e\u4e0b\u8f7d<\/span><\/strong><\/span><\/section>\n<\/section>\n


<\/span><\/p>\n

<\/span><\/p>\n

\"\u836f\u5b66\u7814\u7a76\u6587\u732e\u68c0\u7d22\u7ecf\u9a8c\u5206\u4eab\"<\/p>\n

\u5c0f\u7f16\u7684\u89e3\u51b3\u65b9\u6848\u662f\u201cGoogle\u5b66\u672f+SCI-HUB<\/strong>\u201d\u7684\u795e\u5668\u7ec4\u5408\uff1a\u5148\u7528Google\u5b66\u672f\u8fdb\u884c\u68c0\u7d22\uff0c\u627e\u5230\u9700\u8981\u7684\u6587\u732e\uff0c\u518d\u4f7f\u7528SCI-HUB\u4e0b\u8f7d\u3002\u4f46\u4e00\u8bf4\u5230Google\uff0c\u5f88\u591a\u4eba\u7684\u7b2c\u4e00\u53cd\u5e94\u8fd8\u662f\u201c\u8c37\u6b4c\u4e0d\u662f\u9000\u51fa\u4e2d\u56fd\u4e86\u5417\uff0c\u8fd8\u600e\u4e48\u7528\uff1f\u201d\u3002\u5b9e\u9645\u4e0a\u4e2d\u56fd\u5c01\u9501\u8c37\u6b4c\u4e0d\u5047\uff0c\u8c37\u6b4c\u9000\u51fa\u4e2d\u56fd\u4e5f\u4e0d\u5047\uff0c\u4f46\u8c37\u6b4c\u641c\u7d22\u5728\u56fd\u5185\u8fd8\u662f\u53ef\u4ee5\u4f7f\u7528\u7684\u4e5f\u662f\u4e8b\u5b9e\u3002\u53ea\u4e0d\u8fc7\u5f97\u8d70\u4e0b\u5f2f\u8def\uff0c\u501f\u52a9\u4e0b\u955c\u50cf\u7f51\u7ad9\u3002\u81f3\u4e8e\u955c\u50cf\u7f51\u7ad9\u662f\u4e2a\u4ec0\u4e48\u4e1c\u4e1c\uff0c\u4f5c\u4e3a\u4e00\u4e2a\u8ba1\u7b97\u673a\u4e8c\u7ea7\u90fd\u6ca1\u8003\u8fc7\u7684loser\uff0c\u8bf4\u5b9e\u5728\u8bdd\uff0c\u5728\u767e\u5ea6\u767e\u79d1\u4e0a\u770b\u4e86\u4e00\u904d\u4ecb\u7ecd\u6123\u662f\u6ca1\u6709\u6574\u660e\u767d\uff0c\u4f46\u4ed6\u7684\u5f3a\u5927\u5374\u662f\u5b9e\u5b9e\u5728\u5728\u7684\u3002\u90a3\u4e48\u5230\u5e95\u600e\u4e48\u4e0a\u5462\uff1f\u5c0f\u7f16\u7684\u4e60\u60ef\u662f\u501f\u52a9\u5ea6\u5a18\uff0c\u76f4\u63a5\u641c\u7d22\u201cGoogle\u5b66\u672f\u955c\u50cf\u201d\uff0c\u5373\u53ef\u641c\u7d22\u5230\u591a\u4e2a\u955c\u50cf\u5bfc\u822a\u7f51\u7ad9\uff0c\u591a\u8bd5\u8bd5\uff0c\u627e\u4e2a\u7a33\u5b9a\u7684\u6536\u85cf\u4e86\u5c31\u53ef\u4ee5\u4e86\uff08\u63a8\u8350\u4e00\u4e2a\uff1a<\/span>https:\/\/ab.waguge.com\/<\/span>\uff0c<\/span>\u8fd8\u4e0d\u9519\u54e6\uff09\u3002\u4e07\u4e00\u54ea\u5929\u6302\u4e86\uff0c\u5c31\u518d\u6b21\u6c42\u52a9\u5ea6\u5a18\u3002\u81f3\u4e8eSCI-HUB\uff0c\u5982\u679c\u4f60\u77e5\u9053\u5b83\u5e76\u5df2\u7528\u8fc7\uff0c\u5b9a\u4f1a\u611f\u53f9\u5176\u5f3a\u5927\uff1b\u5982\u679c\u6682\u65f6\u8fd8\u6ca1\u7528\u8fc7\uff0c\u90a3\u4e48\u7528\u8fc7\u4e4b\u540e\u5fc5\u4f1a\u5fc3\u751f\u76f8\u89c1\u6068\u665a\u4e4b\u611f\u3002\u8be5\u7f51\u7ad9\u9875\u9762\u6781\u5176\u7b80\u6d01\uff0c\u4f7f\u7528\u4e5f\u975e\u5e38\u7b80\u4fbf\uff1a\u5c06\u68c0\u7d22\u5230\u7684\u6587\u732e\u5168\u540d\uff0c\u6216\u7f51\u5740\uff0c\u6216DOI\u76f4\u63a5\u8f93\u5165\u5230\u641c\u7d22\u6846\u5185\uff0c\u70b9\u51fb\u201copen\u201d\uff0c\u5373\u53ef\u4e0b\u8f7d\u6587\u732e\u5168\u6587—-\u5c31\u662f\u8fd9\u4e48\u7b80\u5355\u7c97\u66b4\u3002<\/strong>\u5f53\u7136\uff0c\u4e5f\u5e76\u975e\u6240\u6709\u82f1\u6587\u6587\u732e\u5747\u80fd\u4e0b\u8f7d\uff0c\u5c24\u5176\u662f\u6700\u65b0\u7684\u6587\u732e\u3002\u800c\u4e14\u6709\u65f6\u4e0b\u8f7d\u7684\u4f1a\u662fManuscript\u7248\u672c\uff0c\u9605\u8bfb\u4e0d\u5982\u6700\u7ec8\u53d1\u8868\u7248\u65b9\u4fbf\uff0c\u4f46\u804a\u80dc\u4e8e\u65e0\u3002\u82e5\u5b9e\u5728\u65e0\u6cd5\u4e0b\u8f7d\u6216\u53d7\u4e0d\u4e86Manuscript\u7248\u672c\u7684\u9ebb\u70e6\uff0c\u53ea\u80fd\u518d\u6362\u5176\u4ed6\u65b9\u6cd5\u4e0b\u8f7d\u4e86\u3002SCI-HUB\u7684\u7f51\u5740\u4e5f\u633a\u591a\uff0c<\/span>http:\/\/sci-hub.nu\/<\/span>\u548c<\/span>https:\/\/sci-hub.tw\/<\/span>\u662f\u76ee\u524d\u6bd4\u8f83\u7a33\u5b9a\u7684\u4e24\u4e2a\uff0c\u4e07\u4e00\u6302\u4e86\uff0c\u540c\u6cd5\u6c42\u52a9\u5ea6\u5a18\u3002<\/span><\/p>\n

 <\/span><\/p>\n

\u5173\u4e8e<\/span><\/span>Google<\/span>\u5b66\u672f\u68c0\u7d22\u7684\u5c0f\u6280\u5de7\u4e5f\u4e0e\u5927\u5bb6\u5206\u4eab\u4e00\u4e0b\uff0c\u5c0f\u7f16\u662f\u505a\u8d28\u91cf\u7814\u7a76\u5de5\u4f5c\u7684\uff0c\u7ecf\u5e38\u68c0\u7d22\u5206\u6790\u65b9\u6cd5\u548c\u6742\u8d28\u7814\u7a76\u65b9\u9762\u7684\u6587\u732e\uff0c\u4e2a\u4eba\u7684\u4e60\u60ef\u662f\u4ee5<\/span>\u201c<\/span>API<\/span><\/strong>\u540d\u79f0<\/span><\/span><\/strong>+HPLC\/MS\/Impurty\/Degradation\/Stability<\/span><\/strong>\u201d\u4e3a\u5173\u952e\u8bcd<\/span><\/strong>\u8fdb\u884c\u68c0\u7d22\uff0c\u7b5b\u9009\u5f15\u7528\u6b21\u6570\u8f83\u591a\u7684\u6587\u732e\uff0c\u901a\u5e38\u5c31\u80fd\u591f\u627e\u5230\u5177\u6709\u53c2\u8003\u4ef7\u503c\u7684\u6587\u732e\u3002\u800c\u5728<\/span><\/span>Google<\/span>\u5b66\u672f\u5217\u51fa\u7684\u5f15\u6587\u91cc\u518d\u6b21\u7b5b\u9009\uff0c\u901a\u5e38\u80fd\u627e\u5230\u6700\u65b0\u7684\u76f8\u5173\u6587\u732e\u3002<\/span><\/span><\/p>\n

 <\/span><\/p>\n

\u73b0\u5728\u611f\u89c9\u767e\u5ea6\u5b66\u672f\u5176\u5b9e\u4e5f\u86ee\u4e0d\u9519\u7684\uff0c\u90e8\u5206\u6587\u732e\u53ef\u76f4\u63a5\u68c0\u7d22\u5230<\/span>\u201c\u514d\u8d39\u4e0b\u8f7d\u201d\u7684\u94fe\u63a5\uff1b\u5982\u82e5\u6ca1\u6709\uff0c\u4f7f\u7528\u201c\u6c42\u52a9\u5168\u6587\u201d\uff0c\u7528\u5fae\u4fe1\u6216\u767e\u5ea6<\/span>APP<\/span>\u626b\u7801\u5373\u53ef\u514d\u8d39\u53d1\u5e03\u6c42\u52a9\uff0c\u867d\u7136\u6bcf\u5929\u53ea\u6709<\/span><\/span>2<\/span>\u4e2a\u6216<\/span><\/span>5<\/span>\u4e2a\u7684\u514d\u8d39\u673a\u4f1a\uff0c\u4f46\u5e94\u8be5\u4e5f\u8db3\u591f\u7528\u7684\u4e86\u3002\u4f7f\u7528<\/span><\/span>SCI-HUB<\/span><\/strong>\u65e0\u6cd5\u4e0b\u8f7d\u5230\u7684\u6587\u732e\uff0c\u5c0f\u7f16\u901a\u5e38\u5c31\u4f7f\u7528\u767e\u5ea6\u5b66\u672f\u53d1\u5e03\u514d\u8d39\u6c42\u52a9\uff0c\u6c42\u52a9\u6210\u529f\u7387\u548c\u901f\u5ea6\u8fd8\u662f\u86ee\u4e0d\u9519\u7684\u3002\u4f46\u6709\u4e2a\u95ee\u9898\u662f\uff0c\u5982\u679c\u662f\u4f7f\u7528<\/span><\/span>SCI-HUB<\/span><\/strong>\u4e0b\u8f7d\u4e86<\/span><\/span>Manuscript<\/span>\u7248\u672c\u770b\u7740\u4e0d\u723d\uff0c\u60f3\u627e\u6700\u7ec8\u53d1\u8868\u7248\u672c\uff0c\u5c31\u4e0d\u8981\u4f7f\u7528\u767e\u5ea6\u5b66\u672f\u6c42\u52a9\u4e86\u3002\u56e0\u4e3a\u5c0f\u7f16\u53d1\u73b0\uff0c\u8fd9\u79cd\u60c5\u51b5\u4e0b\u767e\u5ea6\u5b66\u672f\u6c42\u52a9\u6765\u7684\u4e5f\u90fd\u662f<\/span><\/span>Manuscript<\/span>\u7248\u672c\u3002\u9047\u6b64\u60c5\u51b5\u65f6\uff0c\u5c31\u53ea\u80fd\u9009\u62e9\u6700\u540e\u7684\u65b9\u6cd5\uff1a\u53bb\u5c0f\u6728\u866b\u6216\u5176\u4ed6\u8bba\u575b\u82b1\u91d1\u5e01\u6c42\u52a9\u4e86\uff0c\u4f46\u6c42\u52a9\u65f6\u4e00\u5b9a\u8981\u6807\u660e<\/span><\/span>\u9700\u8981\u6700\u7ec8\u53d1\u8868\u7248\u672c<\/span><\/span><\/strong>\u3002<\/span><\/span> <\/span><\/p>\n

<\/span><\/p>\n


<\/p>\n

\n
\"\u836f\u5b66\u7814\u7a76\u6587\u732e\u68c0\u7d22\u7ecf\u9a8c\u5206\u4eab\"<\/section>\n
\u65e5\u672c<\/span>IF<\/span>\u6587\u4ef6\u7684\u68c0\u7d22\u4e0e\u4e0b\u8f7d<\/span><\/strong><\/span><\/section>\n<\/section>\n


<\/p>\n

IF\uff08Interview Form\uff09\u6587\u4ef6\u662f\u7531\u65e5\u672c\u836f\u5242\u5e08\u534f\u4f1a\u5411\u533b\u836f\u751f\u4ea7\u4f01\u4e1a\u8bf7\u6c42\u63d0\u4f9b\u7684\u5173\u4e8e\u4e0a\u5e02\u836f\u54c1\u7684\u8d44\u6599\uff0c\u9664\u4e86\u7533\u62a5\u65f6\u7684\u8d44\u6599\uff0c\u8fd8\u4f1a\u6709\u4e0a\u5e02\u540e\u7684\u4e00\u4e9b\u8d44\u6599\uff0c\u5176\u7528\u9014\u662f\u7ed9\u533b\u5e08\u836f\u5e08\u73b0\u573a\u7528\u836f\u63d0\u4f9b\u53c2\u8003\u4fe1\u606f\uff0c\u5176\u5185\u5bb9\u5305\u62ec\u836f\u54c1\u8d28\u91cf\u8d44\u6599\u3001\u5904\u65b9\u8bbe\u8ba1\u8d44\u6599\u3001\u5236\u5242\u5236\u5907\u8d44\u6599\u53ca\u6b63\u786e\u4f7f\u7528\u533b\u836f\u54c1\u8d44\u6599\u7b49\u3002\u5bf9\u4e8e\u4eff\u5236\u836f\u7814\u7a76\u8005\u800c\u8a00\uff0c\u5b9e\u5728\u662f\u975e\u5e38\u6709\u4ef7\u503c\u7684\u53c2\u8003\u8d44\u6599\u3002<\/span>
<\/p>\n

<\/span><\/p>\n

\"\u836f\u5b66\u7814\u7a76\u6587\u732e\u68c0\u7d22\u7ecf\u9a8c\u5206\u4eab\"<\/p>\n


<\/span><\/p>\n

\u5173\u4e8e\u5982\u4f55\u5728<\/span>PMDA<\/span>\u7f51\u7ad9\u4e0b\u8f7d<\/span>IF<\/span>\u6587\u4ef6\uff0c\u836f\u4e8b\u7eb5\u6a2a\u5c0f\u7f16<\/span>Small fish<\/span>\u66fe\u64b0\u6587\u8be6\u8ff0\uff08<\/span>https:\/\/mp.weixin.qq.com\/s\/2x4CHxZZIdpl8_aWgV__kw<\/span><\/a>\uff09\uff0c\u6b64\u5904\u672c\u5c0f\u7f16\u4e3b\u8981\u7ed9\u5927\u5bb6\u63a8\u8350\u4e00\u4e2a\u65e5\u6587\u836f\u54c1\u540d\u7ffb\u8bd1\u7f51\u7ad9<\/span>—<\/span>\u65e5\u672c\u836f\u54c1\u901a\u7528\u540d\u6570\u636e\u5e93\uff08<\/span>http:\/\/moldb.nihs.go.jp\/jan\/<\/span>\uff09\u3002\u5728\u6b64\u6570\u636e\u5e93\u5185\uff0c\u53ef\u901a\u8fc7<\/span>API<\/span>\u7684\u82f1\u6587\u540d\u3001\u5316\u5b66\u540d\u6216<\/span>CAS<\/span>\u53f7\u68c0\u7d22\u5230\u6807\u51c6\u7684\u65e5\u6587\u540d\u79f0\uff0c\u518d\u5c06\u8be5\u540d\u79f0\u590d\u5236\u5230<\/span>PMDA<\/span>\u7f51\u7ad9\u53bb\u68c0\u7d22\uff0c\u53ef\u5927\u5927\u63d0\u9ad8\u68c0\u7d22\u7684\u51c6\u786e\u6027\u3002\u7ffb\u8bd1\u7f51\u7ad9\u6709\u65f6\u7ffb\u8bd1\u7684\u5e76\u4e0d\u51c6\u786e\uff0c\u4ece\u800c\u5bfc\u81f4\u68c0\u7d22\u4e0d\u5230\u60f3\u8981\u7684\u7ed3\u679c\u3002<\/span><\/p>\n

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\n
\"\u836f\u5b66\u7814\u7a76\u6587\u732e\u68c0\u7d22\u7ecf\u9a8c\u5206\u4eab\"<\/section>\n
\u82f1\u6587\u539f\u7248\u7535\u5b50\u4e66\u7684\u68c0\u7d22\u4e0e\u4e0b\u8f7d<\/span><\/strong><\/span><\/section>\n<\/section>\n


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\u8bf4\u5230\u82f1\u6587\u539f\u7248\u7535\u5b50\u4e66\uff0c\u5c31\u4e0d\u5f97\u4e0d\u611f\u6168\u8bed\u8a00\u7684\u5f3a\u5927\u4e0e\u4e0d\u516c\u3002\u82f1\u8bed\u4f5c\u4e3a\u4e16\u754c\u901a\u7528\u8bed\u8a00\uff0c\u5728\u836f\u5b66\u4e13\u4e1a\u9886\u57df\u7684\u5730\u4f4d\u51e0\u4e4e\u662f\u5784\u65ad\u6027\u7684\uff0c\u6743\u5a01\u7684\u4e13\u4e1a\u671f\u520a\u548c\u4e66\u7c4d\u51e0\u4e4e\u90fd\u662f\u82f1\u6587\u7684\uff0c\u4e3a\u6570\u4e0d\u591a\u7684\u4e2d\u6587\u7684\u7ecf\u5178\u4e13\u4e1a\u4e66\u7c4d\uff08\u6559\u6750\u9664\u5916\uff09\u4e5f\u591a\u6570\u662f\u82f1\u6587\u7ffb\u8bd1\u800c\u6765\u7684\uff0c\u800c\u4e14\u7248\u672c\u4e5f\u5747\u8f83\u8001\u4e86\u3002\u4ee5\u5de5\u4e1a\u836f\u5242\u5b66\u7ecf\u5178\u4e66\u7c4d\u300a\u5de5\u4e1a\u836f\u5242\u5b66\u7684\u7406\u8bba\u4e0e\u5b9e\u8df5\u300b\u4e3a\u4f8b\uff0c\u73b0\u4e2d\u6587\u7248\u8fd8\u662f<\/span>1984<\/span>\u5e74\u51fa\u7248\u7684\u7531\u5317\u533b\u7ffb\u8bd1\u7684\u7b2c\u4e8c\u7248\uff0c\u800c\u82f1\u6587\u539f\u7248\u73b0\u5728\u5df2\u66f4\u65b0\u81f3\u7b2c\u56db\u7248\u3002\u79d1\u6280\u53d1\u5c55\u65e5\u65b0\u6708\u5f02\uff0c\u4e09\u5341\u591a\u5e74\u8fc7\u53bb\u4e86\uff0c\u5176\u4e2d\u5dee\u8ddd\u53ef\u60f3\u800c\u77e5\u3002\u8d28\u91cf\u7814\u7a76\u9886\u57df\u6709\u5173\u7a33\u5b9a\u6027\u7814\u7a76\u3001\u9057\u4f20\u6bd2\u6027\u6742\u8d28\u63a7\u5236\u7b56\u7565\u3001\u6676\u578b\u7814\u7a76\u7684\u3001<\/span>HPLC<\/span>\u65b9\u6cd5\u5f00\u53d1\u3001\u65b9\u6cd5\u5b66\u9a8c\u8bc1\u3001\u5305\u6750\u76f8\u5bb9\u6027\u7814\u7a76\u7b49\u7684\u4e13\u4e1a\u4e66\u7c4d\uff0c\u4e2d\u6587\u7248\u5be5\u5be5\u65e0\u51e0\uff0c\u800c\u82f1\u6587\u7248\u5374\u6709\u5f88\u591a\u9009\u62e9\u3002\u82f1\u6587\u4e13\u4e1a\u4e66\u7c4d\u4e0d\u4ec5\u6db5\u76d6\u8303\u56f4\u5e7f\uff0c\u800c\u4e14\u8bb2\u89e3\u7cfb\u7edf\u3001\u8be6\u5b9e\uff0c\u53ef\u80fd\u6211\u4eec\u611f\u89c9\u53ea\u662f\u4e2a\u5c0f\u77e5\u8bc6\u70b9\u7684\u5185\u5bb9\uff0c\u5927\u5496\u4eec\u5374\u53ef\u4ee5\u7f16\u7e82\u6210\u6574\u6574\u4e00\u672c\u4e66\u3002\u5c0f\u7f16\u4e4b\u524d\u5411\u5927\u5bb6\u63a8\u8350\u8fc7\u7684\u300a\u836f\u7269\u964d\u89e3\u8bd5\u9a8c\uff08\u7b2c\u4e8c\u7248\uff09\u300b\uff08\u300a<\/span>Pharmaceutical Stress Testing<\/span>\u300b\uff09\uff0c\u5168\u4e66<\/span>24<\/span>\u4e2a\u7ae0\u8282\u5171<\/span>612<\/span>\u9875\uff01\uff01\u662f\u4e0d\u662f\u5f88\u597d\u5947\u4e00\u4e2a\u964d\u89e3\u8bd5\u9a8c\u6709\u4ec0\u4e48\u8bb2\u5934\uff0c\u8fd8\u80fd\u7f16\u6210\u4e00\u672c\u4e66\uff1f\u8fd8\u8fd9\u4e48\u539a\uff01\uff01\u4f46\u4e8b\u5b9e\u5c31\u662f\u8fd9\u6837\uff0c\u5c0f\u7f16\u5b66\u4e60\u8be5\u4e66\u7684\u65f6\u5019\u5185\u5fc3\u6d3b\u52a8\u7ecf\u5e38\u662f\u8fd9\u6837\u7684\uff1a\u201c\u554a\uff0c\u8fd8\u53ef\u4ee5\u8fd9\u6837\uff1f\u201d\u201c\u54e6<\/span>~<\/span>\uff0c\u539f\u6765\u662f\u8fd9\u6837\uff01\u201d\uff0c\u8d8a\u770b\u8d8a\u89c9\u5f97\u81ea\u5df1\u5b64\u964b\u5be1\u95fb\uff0c\u8d8a\u89c9\u5f97\u81ea\u5df1\u77e5\u9053\u7684\u592a\u5c11\u3002\u82e5\u80fd\u5b66\u5b8c\u672c\u4e66\uff0c\u878d\u4f1a\u8d2f\u901a\uff0c\u5bf9\u81ea\u5df1\u4e13\u4e1a\u57fa\u7840\u7edd\u5bf9\u80fd\u591f\u66f4\u52a0\u7cfb\u7edf\u5168\u9762\uff0c\u4e13\u4e1a\u6c34\u5e73\u4e5f\u5b9a\u80fd\u5f97\u5230\u8d28\u7684\u63d0\u9ad8\u3002\u65e0\u5948\u5c0f\u7f16\u82f1\u6587\u6c34\u5e73\u6709\u9650\uff0c\u770b\u5f97\u5b9e\u5728\u6162\u4e9b\uff0c\u5feb\u4e00\u5e74\u8fc7\u53bb\u4e86\u8fd8\u672a\u80fd\u5b66\u5b8c\uff0c\u4f46\u6536\u83b7\u786e\u5b9e\u662f\u6ee1\u6ee1\u7684\u3002\u5c0f\u7f16\u63a8\u8350\u8fc7\u7684\u53e6\u5916\u4e00\u672c\u836f\u7269\u964d\u89e3\u5316\u5b66\u6709\u5173\u7684\u4e66\u7c4d<\/span>—<\/span>\u674e\u654f\u8001\u5e08\u6240\u8457\u7684\u300a<\/span>Organic Chemistry of Drug Degradation<\/span>\u300b\uff0c\u56db\u6708\u4efd\u53c2\u52a0\u67d0\u57f9\u8bad\u65f6\uff0c\u674e\u654f\u8001\u5e08\u81ea\u5df1\u8bf4\u4e2d\u6587\u8bd1\u672c\u9a6c\u4e0a\u5c31\u8981\u51fa\u7248\u4e86\uff0c\u611f\u5174\u8da3\u7684\u5c0f\u4f19\u4f34\u53ef\u4ee5\u5173\u6ce8\u4e0b\u3002<\/span>
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\"\u836f\u5b66\u7814\u7a76\u6587\u732e\u68c0\u7d22\u7ecf\u9a8c\u5206\u4eab\"<\/p>\n


<\/span><\/p>\n

\u5570\u55e6\u4e86\u8fd9\u4e48\u591a\uff0c\u90fd\u662f\u5c0f\u7f16\u4e2a\u4eba\u7684\u611f\u6168\uff0c\u8fd8\u662f\u7565\u5fae\u6536\u655b\u4e00\u4e0b\uff0c\u6b63\u5f0f\u5411\u5927\u5bb6\u5206\u4eab\u4e00\u4e0b\u4e0b\u8f7d\u82f1\u6587\u539f\u7248\u7535\u5b50\u4e66\u7684\u7ecf\u9a8c\u5427\u3002\u5176\u5b9e\u82f1\u6587\u539f\u7248\u7535\u5b50\u4e66\u901a\u8fc7<\/span>SCI-HUB<\/span>\u4e5f\u80fd\u4e0b\u8f7d\uff0c\u5c0f\u7f16\u5411\u5927\u5bb6\u63a8\u8350\u7684\u8fd9\u4e2a\u6570\u636e\u5e93\u4e5f\u662f\u5728\u4f7f\u7528<\/span>SCI-HUB<\/span>\u4e0b\u8f7d\u65f6\u5076\u7136\u88ab\u53d1\u73b0\u7684\uff0c\u5373<\/span>Library Genesis<\/span>2M<\/span><\/sup>\uff08<\/span>http:\/\/libgen.io\/<\/span>\uff09\uff0c\u529f\u80fd\u4e5f\u5f02\u5e38\u5f3a\u5927\uff0c\u76f4\u63a5\u6309\u4e66\u540d\u68c0\u7d22\u5373\u53ef\u3002\u5982\u60f3\u4e0b\u8f7d\u300a<\/span>Pharmaceutical Dosage Forms: Tablets, Third Edition<\/span>\u300b\uff0c\u5728\u68c0\u7d22\u6846\u8f93\u5165\u4e66\u540d\u540e\u641c\u7d22\uff0c\u6309\u63d0\u793a\u4e00\u6b65\u6b65\u64cd\u4f5c\uff0c\u5373\u53ef\u8fdb\u5165\u4e0b\u56fe\u6240\u793a\u5217\u8868\u53ca\u4e0b\u8f7d\u754c\u9762\uff0c\u4e0b\u8f7d\u5f97\u5230<\/span>PDF<\/span>\u7248\u3002<\/span>
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\"\u836f\u5b66\u7814\u7a76\u6587\u732e\u68c0\u7d22\u7ecf\u9a8c\u5206\u4eab\"<\/p>\n

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\u597d\u4e86\uff0c\u5c31\u548c\u5927\u5bb6\u5206\u4eab\u8fd9\u4e9b\uff0c\u5e0c\u671b\u80fd\u7ed9\u5927\u5bb6\u5e26\u53bb\u5e2e\u52a9\u3002\u5c0f\u7f16\u53c2\u52a0\u57f9\u8bad\u65f6\u542c\u8fc7\u591a\u4e3a\u4e1a\u5185\u5927\u5496\u7684\u6388\u8bfe\uff0c\u5404\u4f4d\u5927\u5496\u5728\u8fdb\u884c\u7814\u7a76\u5de5\u4f5c\u65f6\u5747\u5c1a\u4e14\u9700\u501f\u52a9\u6587\u732e\uff0c\u6211\u7b49\u5c0f\u5175\u5219\u66f4\u9700\u7ad9\u5728\u5de8\u4eba\u7684\u80a9\u8180\u4e0a\u524d\u884c\u3002\u6587\u732e\u8c03\u7814\u7684\u7cfb\u7edf\u5168\u9762\uff0c\u53ef\u4f7f\u7814\u7a76\u5de5\u4f5c\u66f4\u52a0\u7cfb\u7edf\u5168\u9762\uff0c\u7814\u7a76\u6c34\u5e73\u5f97\u5230\u6709\u6548\u63d0\u5347\uff0c\u5c24\u5176\u5bf9\u4e8e\u4eff\u5236\u836f\u7814\u7a76\u8005\u6765\u8bf4\uff0c\u5f80\u5f80\u80fd\u8fbe\u5230\u4e8b\u534a\u529f\u500d\u7684\u6548\u679c\u3002<\/span><\/p>\n


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\u6392\u7248\uff1a\u9621\u4e0a\u964c\u964c<\/span><\/p>\n

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\u5e7f\u800c\u544a\u4e4b<\/section>\n<\/section>\n<\/section>\n
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\u2299 \u540c\u5199\u610f\u57f9\u8bad<\/span><\/p>\n

\u5199\u610f\u8bba\u575b\u4e28\u65b0\u836f\u4e2d\u7f8e\u53cc\u62a5\u4e4b\u5236\u5242\u6eb6\u51fa\u6280\u672f\u5f00\u53d1<\/a><\/span><\/p>\n

\u5199\u610f\u8bba\u575b\u4e28\u56fd\u9645\u89c4\u8303\u4e0b\u751f\u7269\u836f\u5168\u751f\u547d\u5468\u671f\u8d28\u91cf\u7ba1\u7406<\/a><\/span><\/p>\n

\u5199\u610f\u516c\u76ca\u4e28\u4eff\u5236\u836f\u4e00\u81f4\u6027\u8bc4\u4ef7\u5927\u76d8\u70b9\u4e0e\u603b\u51b3\u6218<\/span><\/a><\/p>\n

\u6ee1\u8db3IND\/NDA\u4e2d\u7f8e\u53cc\u62a5\u7684\u53e3\u670d\u65b0\u836f\u5236\u5242\u7814\u53d1<\/a><\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n

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\"\u836f\u5b66\u7814\u7a76\u6587\u732e\u68c0\u7d22\u7ecf\u9a8c\u5206\u4eab\"<\/p>\n

\u836f\u4e8b\u7eb5\u6a2a\u662f\u4e00\u4e2a\u5f00\u653e\uff0c\u7531\u81ea\u613f\u8005\u7ec4\u6210\u7684\u56e2\u4f53\uff0c\u73b0\u6709\u6210\u545838\u540d\uff0c\u5206\u522b\u4e3aVoyager88\uff08\u9b4f\u5229\u519b\uff09\uff0c\u96f7\u8bfa\u5c9b\uff0c\u4e09\u5206\u8bdd\uff0cHerman\uff0c\u6885\u5e0c\uff0c\u6587\u7af9\uff0cduke\uff0cyhqqqqq\uff0c\u5360\u5c0f\u5175\uff0c\u98ce\u4e00\u6837\u7684\u5c4e\u58f3\u90ce\uff0c\u9526\u5fc3\u7ee3\u53e3\uff0cflydp511\uff0c\u5de7\u5de7\uff0c\u4e91\u6c34\u9053\u4eba\uff0c\u9621\u4e0a\u964c\u964c\uff0c\u591a\u5df4\u80fa\uff0c\u745c\u513f\uff0cKailyn\uff0cSmall fish\uff0c\u5b50\u708e\uff0c\u514b\u683c\u83ab\uff0cVicky\uff0cPandada\uff0c\u83ab\u5306\u5306\uff0cSophia \uff0c\u4f9d\u7136\u7279\u96f7\u897f\uff0c\u5076\u9635\u96e8\uff0cAimee\uff0c\u4ed6\u5c71\u4e4b\u77f3\uff0c\u5510\u5c0f\u7396\uff0c\u96f6\u4e0b274\u2103\uff0cGloria\uff0cBreathless\uff0cLuffy\uff0c\u80e1\u4e0d\u559c\uff0c Helen\uff0c\u843d\u843d\uff0cSUNRISE\u3002\u6b22\u8fce\u6709\u5fd7\u4e4b\u58eb\u52a0\u5165\u6211\u4eec\u56e2\u961f\u3002\u6295\u7a3f\u3001\u5408\u4f5c\u3001\u52a0\u4e13\u4e1a\u7fa4\u8bf7\u52a0\u5fae\u4fe1442015666\uff0c\u836f\u4e8b\u7eb5\u6a2a\u4e8c\u5343\u4ebaQQ\u7fa422711855\u3002<\/span><\/p>\n

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