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\n


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2018\u5e747\u670813\u65e5SIGA \u516c\u53f8\u7684tecovirimat<\/span> <\/span>\uff08<\/span>TPOXX\uff09\u836f\u7269\u83b7\u5f97\u4e86FDA\u7684\u6279\u51c6\uff0c\u8fd9\u662f\u9996\u6b21\u83b7\u6279\u7684\u7528\u4e8e\u6cbb\u7597\u5929\u82b1\uff08small pox\uff09\u7684\u836f\u7269\uff0cTPOXX\u662f\u4e00\u79cd\u6cbb\u7597\u5929\u82b1\u611f\u67d3\u7684\u521b\u65b0\u5c0f\u5206\u5b50\u6297\u75c5\u6bd2\u7597\u6cd5\u3002\u66fe\u83b7\u5f97\u4e86\u5feb\u901f\u901a\u9053\u8d44\u683c\u3001\u4f18\u5148\u5ba1\u8bc4\u8d44\u683c\u3001\u4ee5\u53ca\u5b64\u513f\u836f\u8d44\u683c\uff0c\u4e5f\u662fFDA\u4eca\u5e74\u6279\u51c6\u7684\u7b2c21\u6b3e\u65b0\u836f\u3002<\/p>\n<\/p>\n

 <\/p>\n

Tecovirimat\u7684\u7ed3\u6784\u5f0f\uff08\u56fe\u7247\u6765\u6e90\uff1aSIGA\u516c\u53f8\u5b98\u7f51\uff09<\/p>\n

 <\/p>\n

\u5929\u82b1\u662f\u7531\u5929\u82b1\u75c5\u6bd2\u5f15\u8d77\u7684\u4e00\u79cd\u70c8\u6027\u4f20\u67d3\u75c5\uff0c\u5176\u4e3b\u8981\u7ecf\u547c\u5438\u9053\u9ecf\u819c\u4fb5\u5165\u4eba\u4f53\uff0c\u901a\u8fc7\u98de\u6cab\u5438\u5165\u6216\u76f4\u63a5\u63a5\u89e6\u800c\u4f20\u67d3\uff0c\u67d3\u75c5\u540e\u6b7b\u4ea1\u7387\u9ad8\uff0c\u5929\u82b1\u75c5\u6bd2\u6709\u6bd2\u529b\u4e0d\u540c\u7684\u4e24\u578b\u75c5\u6bd2\u682a\uff0c\u6bd2\u529b\u5f3a\u7684\u5f15\u8d77\u6b63\u578b\u5929\u82b1\uff0c\u5373\u5178\u578b\u5929\u82b1\uff1b\u5f31\u8005\u5f15\u8d77\u8f7b\u578b\u5929\u82b1\uff0c\u5373\u7c7b\u5929\u82b1\u3002<\/span>\u4e3b\u8981\u4e34\u5e8a\u8868\u73b0\u4e3a\u4e25\u91cd\u6bd2\u8840\u75c7\u72b6\u3001\u76ae\u80a4\u6210\u6279\u4f9d\u6b21\u51fa\u73b0\u6591\u75b9\u3001\u4e18\u75b9\u3001\u75b1\u75b9\u3001\u8113\u75b1\uff0c\u6700\u540e\u7ed3\u75c2\u3001\u8131\u75c2\uff0c\u9057\u7559\u75d8\u75a4\uff0c\u6b64\u75c5\u4e3b\u8981\u4ee5\u9884\u9632\u4e3a\u4e3b\uff0c\u6700\u57fa\u672c\u6709\u6548\u800c\u53c8\u6700\u7b80\u4fbf\u7684\u9884\u9632\u65b9\u6cd5\u662f\u63a5\u79cd\u725b\u75d8\u3002\u4e4b\u524d\u611f\u67d3\u5929\u82b1\u7684\u75c5\u4eba\u901a\u5e38\u662f\u4ee5\u652f\u6301\u7597\u6cd5\u8fdb\u884c\u6cbb\u7597\uff0c\u4f8b\u5982\u9759\u8109\u6ce8\u5c04\u7535\u89e3\u8d28\u3001\u8425\u517b\u54c1\u6216\u4ee5\u836f\u7269\u63a7\u5236\u9ad8\u70e7\u6216\u75bc\u75db\uff0c\u540c\u65f6\u4e5f\u4f1a\u4ee5\u6297\u751f\u7d20\u6765\u9884\u9632\u611f\u67d3\u5929\u82b1\u75c5\u6bd2\u540e\u968f\u4e4b\u800c\u6765\u7684\u7ec6\u83cc\u611f\u67d3\u95ee\u9898\u3002<\/p>\n

 <\/p>\n

\u201c\u867d\u7136\u4e16\u754c\u536b\u751f\u7ec4\u7ec7\u5ba3\u5e03\u5929\u82b1\u65e9\u57281980\u5e74\u5df2\u6839\u9664\uff0c<\/span>\u4f46\u662f\u4ecd\u7136\u6709\u5c11\u91cf\u5929\u82b1\u75c5\u6bd2\u7684\u6837\u672c\u88ab\u50a8\u5b58\u8d77\u6765\u7528\u4e8e\u79d1\u5b66\u7814\u7a76\uff0c\u4f5c\u4e3a\u4e00\u79cd\u4f20\u67d3\u6027\u6781\u5f3a\u3001\u6709\u65f6\u751a\u81f3\u662f\u81f4\u547d\u7684\u4f20\u67d3\u75c5\uff0c\u4eba\u4eec\u957f\u671f\u4ee5\u6765\u4e00\u76f4\u62c5\u5fc3\u5929\u82b1\u88ab\u7528\u4f5c\u751f\u7269\u6b66\u5668\u3002<\/span>\u201d SIGA\u7684\u9996\u5e2d\u6267\u884c\u5b98Phil Gomez\u535a\u58eb\u8bf4: \u201c\u5929\u82b1\u751f\u7269\u6050\u6016\u88ad\u51fb\u53ef\u80fd\u5177\u6709\u7279\u522b\u7684\u7834\u574f\u6027\uff0c\u56e0\u4e3a\u76ee\u524d\u5927\u591a\u6570\u4eba\u90fd\u65e0\u6cd5\u5bf9\u75c5\u6bd2\u514d\u75ab\uff0c\u5929\u82b1\u53ef\u4ee5\u901a\u8fc7\u76f4\u63a5\u63a5\u89e6\u53d7\u611f\u67d3\u7684\u6db2\u4f53\u548c\u53d7\u6c61\u67d3\u7684\u7269\u4f53\u4f20\u64ad\uff0c\u5373\u8bf4\u8bdd\u3001\u547c\u5438\u6216\u89e6\u6478\u5747\u53ef\u5728\u4eba\u4e0e\u4eba\u4e4b\u95f4\u8fc5\u901f\u4f20\u64ad\u3002\u5929\u82b1\u6ca1\u6709\u6cbb\u6108\u6216\u6cbb\u7597\u65b9\u6cd5\uff0c\u4e00\u79cd\u75ab\u82d7\u867d\u7136\u53ef\u4ee5\u9884\u9632\u5929\u82b1\uff0c\u4f46\u662f\u8fd9\u79cd\u75ab\u82d7\u526f\u4f5c\u7528\u7684\u98ce\u9669\u592a\u5927\u4e86\uff0c\u4e0d\u80fd\u4e3a\u90a3\u4e9b\u63a5\u89e6\u5929\u82b1\u75c5\u6bd2\u7684\u4f4e\u98ce\u9669\u4eba\u7fa4\u63d0\u4f9b\u5e38\u89c4\u7684\u75ab\u82d7\u63a5\u79cd\u3002<\/span>\u8fd9\u4e9b\u56e0\u7d20\u51f8\u663e\u4e86\u5bf9\u6709\u6548\u7684\u5929\u82b1\u6297\u75c5\u6bd2\u6cbb\u7597\u7684\u5fc5\u7136\u6027\uff0c\u6211\u4eec\u76f8\u4fe1TPOXX\u53ef\u4ee5\u6ee1\u8db3\u8fd9\u79cd\u9700\u6c42\u3002\u201d<\/p>\n

 <\/p>\n

SIGA Technologies\u662f\u4e00\u5bb6\u4e13\u6ce8\u4e8e\u5f00\u53d1\u4e25\u91cd\u672a\u88ab\u6ee1\u8db3\u533b\u7597\u9700\u6c42\u7684\u516c\u53f8,\u5176\u5f00\u53d1\u7684TPOXX\u80fd\u591f\u963b\u65ad\u5929\u82b1\u75c5\u6bd2\u7684\u4f20\u64ad\uff0c\u5728\u5929\u82b1\u7684\u52a8\u7269\u6a21\u578b\u4e2d\u5b83\u80fd\u591f\u9632\u6b62\u5929\u82b1\u75c7\u72b6\u7684\u4ea7\u751f\u3002<\/span>TPOXX\u6cbb\u7597\u5929\u82b1\u7684\u6709\u6548\u6027\u662f\u901a\u8fc7\u5bf9\u611f\u67d3\u4e86\u4e0e\u5f15\u53d1\u5929\u82b1\u7684\u75c5\u6bd2\u5bc6\u5207\u76f8\u5173\u7684\u75c5\u6bd2\u7684\u52a8\u7269\u8fdb\u884c\u7684\u7814\u7a76\uff0c\u5e76\u4ee5\u52a8\u7269\u5b58\u6d3b\u7387\u4e3a\u4f9d\u636e\u3002\u52a8\u7269\u5b9e\u9a8c\u7ed3\u679c\u663e\u793a\uff0c\u611f\u67d3\u4e86\u8fd9\u7c7b\u5929\u82b1\u75c5\u6bd2\u540e\uff0c\u4f7f\u7528TPOXX\u7684\u52a8\u7269\u6bd4\u4f7f\u7528\u5b89\u6170\u5242\u7684\u5bf9\u7167\u7ec4\u52a8\u7269\u5b58\u6d3b\u7387\u66f4\u9ad8\u3002<\/p>\n


<\/p>\n

\u7ec6\u80de\u57f9\u517b\u548c\u52a8\u7269\u5b9e\u9a8c\u8868\u660e\uff0cTPOXX\u80fd\u591f\u6291\u5236\u725b\u75d8\uff0c\u725b\u75d8\uff0c\u9f20\u75d8\uff0c\u7334\u75d8\uff0c\u5154\u75d8\uff0c\u9a86\u9a7c\u75d8\u548c\u5929\u82b1\uff08\u5929\u82b1\uff09\u590d\u5236\uff0c\u4f46\u4e0d\u6291\u5236\u5176\u4ed6\u65e0\u5173\u75c5\u6bd2\u3002<\/span>\u56e0\u4e3a\u4e16\u754c\u4e0a\u6ca1\u6709\u5929\u82b1\u60a3\u8005\uff0cTPOXX\u7684\u7814\u53d1\u8fc7\u7a0b\u9075\u5faa\u4e86FDA\u4e2d\u201c\u52a8\u7269\u6761\u4f8b\u201d (animal rule)\u3002\u836f\u7269\u7684\u7597\u6548\u5728\u52a8\u7269\u5b9e\u9a8c\u4e2d\u4f53\u73b0\uff0c\u800c\u4eba\u7c7b\u4e34\u5e8a\u8bd5\u9a8c\u7528\u6765\u9a8c\u8bc1\u836f\u7269\u5242\u91cf\u548c\u5b89\u5168\u6027\u3002\u5728359\u540d\u6ca1\u6709\u611f\u67d3\u5929\u82b1\u7684\u5065\u5eb7\u5fd7\u613f\u8005\u4e2d\uff0c\u5bf9TPOXX\u7684\u5b89\u5168\u6027\u8fdb\u884c\u4e86\u8bc4\u4f30\u3002\u7814\u7a76\u8868\u660eTPOXX\u53ef\u80fd\u5728\u4e0d\u963b\u788d\u60a3\u8005\u83b7\u5f97\u514d\u75ab\u80fd\u529b\u7684\u60c5\u51b5\u4e0b\u8d77\u4f5c\u7528\uff0c\u5728\u5065\u5eb7\u5fd7\u613f\u8005\u8eab\u4e0a\u7684\u4e34\u5e8a\u8bd5\u9a8c\u8868\u660e\u670d\u7528TPOXX\u6700\u5e38\u89c1\u7684\u526f\u4f5c\u7528\u662f\u5934\u75db\u3001\u6076\u5fc3\u4ee5\u53ca\u8179\u90e8\u75bc\u75db\uff0c\u6ca1\u6709\u4e25\u91cd\u7684\u526f\u4f5c\u7528\u3002<\/p>\n

 <\/p>\n

TPOXX\u662f\u4e00\u79cd\u65b0\u578b\u4e13\u5229\u836f\u7269\uff0c\u6613\u4e8e\u50a8\u5b58\uff0c\u8fd0\u8f93\u548c\u7ba1\u7406\u3002<\/span>SIGA\u516c\u53f8\u6b63\u5728\u8bc4\u4f30\u8be5\u4ea7\u54c1\u7684\u591a\u79cd\u7528\u9014\uff0c\u4ee5\u964d\u4f4e\u611f\u67d3\u5929\u82b1\u75c5\u6bd2\u7684\u4eba\u7684\u6b7b\u4ea1\u7387\u548c\u53d1\u75c5\u7387\uff0c\u4fdd\u62a4\u75c5\u6bd2\u66b4\u9732\u540e\u60a3\u4e0a\u5929\u82b1\u7684\u975e\u514d\u75ab\u8005\uff0c\u4ee5\u53ca\u4f5c\u4e3a\u5929\u82b1\u7684\u8f85\u52a9\u836f\u7269\u75ab\u82d7\uff0c\u4ee5\u51cf\u5c11\u7531\u4e8e\u7528\u4e8e\u75ab\u82d7\u63a5\u79cd\u7684\u6d3b\u75c5\u6bd2\u5f15\u8d77\u7684\u4e25\u91cd\u4e0d\u826f\u4e8b\u4ef6\u7684\u53d1\u751f\u9891\u7387\u3002\u57282018\u5e745\u67081\u65e5\uff0c\u72ec\u7acb\u533b\u5b66\u4e13\u5bb6\u7ec4\u6210\u7684\u4e13\u5bb6\u7ec4\u4ee517\u6bd40\u7684\u6295\u7968\u7ed3\u679c\u4e00\u81f4\u8ba4\u4e3a\uff0cTPOXX\u7684\u597d\u5904\u5927\u4e8e\u98ce\u9669\u3002\u57fa\u4e8e\u52a8\u7269\u5b9e\u9a8c\u4e2d\u5c55\u73b0\u51fa\u7684\u7597\u6548\uff0c\u4ee5\u53ca\u4eba\u4f53\u8bd5\u9a8c\u8868\u660e\u7684\u5b89\u5168\u6027\uff0c\u7f8e\u56fdFDA\u6279\u51c6\u4e86\u8fd9\u6b3e\u65b0\u836f\u4e0a\u5e02\u3002<\/p>\n

 <\/p>\n

FDA\u5c40\u957fScott Gottlieb\u535a\u58eb\u79f0\uff1a\u201c\u4e3a\u4e86\u5e94\u5bf9\u751f\u7269\u6050\u6016\u4e3b\u4e49\u7684\u98ce\u9669\uff0c\u786e\u4fdd\u75c5\u539f\u4f53\u88ab\u5f53\u505a\u6b66\u5668\u65f6\uff0c\u6211\u4eec\u6709\u7ecf\u8fc7\u5f00\u53d1\u5e76\u83b7\u6279\u7684\u53cd\u5236\u624b\u6bb5\u3002<\/span>TPOXX\u7684\u6279\u51c6\u4ee3\u8868\u4e86\u8fd9\u4e9b\u52aa\u529b\u7684\u91cd\u5927\u91cc\u7a0b\u7891\uff0c\u4e5f\u8868\u660eFDA\u7684\u4e3a\u786e\u4fdd\u516c\u5171\u5065\u5eb7\u5371\u673a\u505a\u597d\u4e86\u51c6\u5907\u3002\u201d<\/p>\n

 <\/p>\n

 <\/p>\n

\u53c2\u8003\u6587\u732e\uff1a<\/p>\n

1.FDA approves the first drug with an indication for treatment of smallpox<\/span><\/h1>\n

2. SIGA Technologies\u5b98\u7f51<\/span><\/p>\n

3.Pivotal Trial Data for SIGA Technologies\u2019 Oral TPOXX\u00ae Published in the New England Journal of Medicine<\/span><\/p>\n

4. SIGA to Present at the Jefferies Global Healthcare Conference on June 8, 2018<\/span><\/p>\n

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\u5e7f\u800c\u544a<\/span>\u4e4b<\/section>\n<\/section>\n<\/section>\n
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\u2299 \u540c\u5199\u610f\u57f9\u8bad<\/span><\/p>\n

\u5199\u610f\u8bba\u575b\u4e28\u65b0\u836f\u4e2d\u7f8e\u53cc\u62a5\u4e4b\u5236\u5242\u6eb6\u51fa\u6280\u672f\u5f00\u53d1<\/a><\/span><\/p>\n

\u5199\u610f\u8bba\u575b\u4e28\u56fd\u9645\u89c4\u8303\u4e0b\u751f\u7269\u836f\u5168\u751f\u547d\u5468\u671f\u8d28\u91cf\u7ba1\u7406<\/a><\/span><\/p>\n

\u5199\u610f\u516c\u76ca\u4e28\u4eff\u5236\u836f\u4e00\u81f4\u6027\u8bc4\u4ef7\u5927\u76d8\u70b9\u4e0e\u603b\u51b3\u6218<\/a><\/p>\n<\/section>\n<\/section>\n<\/section>\n

\u6392\u7248\uff1a\u6587\u7af9<\/p>\n

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\"FDA\u6279\u51c6\u9996\u6b3e\u6cbb\u7597\u5929\u82b1\u7684\u836f\u7269\"<\/p>\n

\u836f\u4e8b\u7eb5\u6a2a\u662f\u4e00\u4e2a\u5f00\u653e\uff0c\u7531\u81ea\u613f\u8005\u7ec4\u6210\u7684\u56e2\u4f53\uff0c\u73b0\u6709\u6210\u545838\u540d\uff0c\u5206\u522b\u4e3aVoyager88\uff08\u9b4f\u5229\u519b\uff09\uff0c\u96f7\u8bfa\u5c9b\uff0c\u4e09\u5206\u8bdd\uff0cHerman\uff0c\u6885\u5e0c\uff0c\u6587\u7af9\uff0cduke\uff0cyhqqqqq\uff0c\u5360\u5c0f\u5175\uff0c\u98ce\u4e00\u6837\u7684\u5c4e\u58f3\u90ce\uff0c\u9526\u5fc3\u7ee3\u53e3\uff0cflydp511\uff0c\u5de7\u5de7\uff0c\u4e91\u6c34\u9053\u4eba\uff0c\u9621\u4e0a\u964c\u964c\uff0c\u591a\u5df4\u80fa\uff0c\u745c\u513f\uff0cKailyn\uff0cSmall fish\uff0c\u5b50\u708e\uff0c\u514b\u683c\u83ab\uff0cVicky\uff0cPandada\uff0c\u83ab\u5306\u5306\uff0cSophia \uff0c\u4f9d\u7136\u7279\u96f7\u897f\uff0c\u5076\u9635\u96e8\uff0cAimee\uff0c\u4ed6\u5c71\u4e4b\u77f3\uff0c\u5510\u5c0f\u7396\uff0c\u96f6\u4e0b274\u2103\uff0cGloria\uff0cBreathless\uff0cLuffy\uff0c\u80e1\u4e0d\u559c\uff0c Helen\uff0c\u843d\u843d\uff0cSUNRISE\u3002\u6b22\u8fce\u6709\u5fd7\u4e4b\u58eb\u52a0\u5165\u6211\u4eec\u56e2\u961f\u3002\u6295\u7a3f\u3001\u5408\u4f5c\u3001\u52a0\u4e13\u4e1a\u7fa4\u8bf7\u52a0\u5fae\u4fe1442015666\uff0c\u836f\u4e8b\u7eb5\u6a2a\u4e8c\u5343\u4ebaQQ\u7fa422711855\u3002<\/span><\/p>\n


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