{"id":20143,"date":"2018-07-13T01:00:00","date_gmt":"2018-08-08T01:16:59","guid":{"rendered":"http:\/\/www.05921.net\/index.php\/2018\/08\/08\/%e5%a4%8d%e6%9d%82%e6%b3%a8%e5%b0%84%e5%89%82%e7%9a%84%e5%b8%82%e5%9c%ba%e6%a6%82%e5%86%b5%e5%92%8c%e5%8f%91%e5%b1%95%e6%9c%ba%e9%81%87\/"},"modified":"2018-08-08T09:17:04","modified_gmt":"2018-08-08T01:17:04","slug":"%e5%a4%8d%e6%9d%82%e6%b3%a8%e5%b0%84%e5%89%82%e7%9a%84%e5%b8%82%e5%9c%ba%e6%a6%82%e5%86%b5%e5%92%8c%e5%8f%91%e5%b1%95%e6%9c%ba%e9%81%87","status":"publish","type":"post","link":"https:\/\/www.05921.net\/index.php\/20143\/","title":{"rendered":"\u590d\u6742\u6ce8\u5c04\u5242\u7684\u5e02\u573a\u6982\u51b5\u548c\u53d1\u5c55\u673a\u9047"},"content":{"rendered":"<div class=\"bpp-post-content\">\n<p style=\"text-align: justify;\"><span style=\"font-size: 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normal;width: 100%;height: auto;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/08\/beepress10-1533691020.png\" alt=\"\u590d\u6742\u6ce8\u5c04\u5242\u7684\u5e02\u573a\u6982\u51b5\u548c\u53d1\u5c55\u673a\u9047\" title=\"\u590d\u6742\u6ce8\u5c04\u5242\u7684\u5e02\u573a\u6982\u51b5\u548c\u53d1\u5c55\u673a\u9047\"  \/><\/p>\n<p style=\"text-align: justify;\"><br  \/><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 15px;\">\u5f97\u76ca\u4e8e\u6211\u56fd\u6ce8\u5c04\u4e73\u5242\u4ea7\u4e1a\u94fe\u7684\u65e5\u76ca\u6210\u719f\uff0c<span style=\"font-size: 15px;text-align: justify;\">\u8fd1\u5e74\u6765\uff0c<\/span><span style=\"font-size: 15px;text-align: justify;\">\u6211\u56fd\u7684\u4e73\u5242\u5e02\u573a\u589e\u957f\u975e\u5e38\u8fc5\u901f\u3002<\/span>\u7136\u800c\u56e0\u4e3a2017\u5e74<span style=\"font-size: 15px;text-align: 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100%;height: auto;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/08\/beepress2-1533691020.png\" alt=\"\u590d\u6742\u6ce8\u5c04\u5242\u7684\u5e02\u573a\u6982\u51b5\u548c\u53d1\u5c55\u673a\u9047\" title=\"\u590d\u6742\u6ce8\u5c04\u5242\u7684\u5e02\u573a\u6982\u51b5\u548c\u53d1\u5c55\u673a\u9047\"  \/><\/p>\n<p style=\"text-align: justify;\"><br  \/><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 15px;\"><strong>\u524d\u5217\u5730\u5c14&nbsp;&nbsp; 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15px;\"><strong>\u4e19\u6cca\u915a&nbsp;&nbsp;<\/strong>\u4e19\u6cca\u915a\u662f\u5168\u7403\u5e02\u573a\u6700\u5927\u7684\u4e73\u5242\uff0c\u4f46\u5728\u4e2d\u56fd\u7684\u8868\u73b0\u5374\u4e0d\u53ca\u524d\u5217\u5730\u5c14\u3002\u4e19\u6cca\u915a\u7531\u963f\u65af\u5229\u5eb7\u548c\u8d39\u68ee\u5c24\u65af\u5f00\u53d1\uff0c1989\u5e74\u83b7\u6279\u4e0a\u5e02\u3002\u4e19\u6cca\u915a\u5728\u9ebb\u9189\u9886\u57df\u5177\u6709\u65e0\u6cd5\u53d6\u4ee3\u7684\u4f18\u52bf\uff0c\u5c3d\u7ba1\u4e13\u5229\u65e9\u5df2\u7ecf\u5230\u671f\uff0c\u4f46IMS\u6570\u636e\u663e\u793a\uff0c\u8be5\u4ea7\u54c1\u7684\u5168\u7403\u9500\u552e\u989d\u4ecd\u7136\u8d85\u8fc711\u4ebf\u7f8e\u5143\u3002\u4e19\u6cca\u915a\u662f\u6c34\u4e0d\u6eb6\u578b\u4ea7\u54c1\uff0c\u81f3\u4eca\u79d1\u5b66\u5bb6\u4eec\u4f9d\u7136\u6ca1\u6709\u627e\u51fa\u6bd4\u4e73\u5242\u66f4\u597d\u7684\u5242\u578b\u6765\u53d6\u4ee3\u4e73\u5242\u3002\u8fd1\u5e74\u6765\uff0c\u6211\u56fd\u4e19\u6cca\u915a\u9500\u552e\u989d\u589e\u957f\u975e\u5e38\u5feb\uff0cIMS\u6570\u636e\u663e\u793a\uff0c\u4e19\u6cca\u915a2016\u5e74\u9500\u552e\u989d\u8fbe2.97\u4ebf\u7f8e\u5143\uff0c2017\u5e74\u9500\u552e\u989d\u589e\u957f\u8d85\u8fc710%\u3002<\/span><\/p>\n<p style=\"text-align: justify;\"><br  \/><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 15px;\"><strong>\u5176\u5b83\u4e73\u5242<\/strong>&nbsp; \u5168\u7403\u4e0a\u5e02\u7684\u8f7d\u836f\u4e73\u5242\u8fd8\u6709\u5730\u585e\u7c73\u677e\u3001\u4f9d\u6258\u54aa\u916f\u3001\u5730\u897f\u6cee\u3001\u963f\u745e\u5339\u5766\u3001\u6c2f\u7ef4\u5730\u5e73\u7b49\uff0c\u4f46\u4e2d\u56fd\u53ea\u6709\u4f9d\u6258\u54aa\u916f\u4e0a\u5e02\u3002\u9664\u6b64\u4e4b\u5916\uff0c\u4e2d\u56fd\u8fd8\u4e0a\u5e02\u4e86\u4e00\u79cd\u4e2d\u836f\u4e73\u5242\uff0c\u5373\u9e26\u80c6\u5b50\u6cb9\u4e73\u5242\u3002\u6c2f\u7ef4\u5730\u5e73\u548c\u963f\u745e\u5339\u5766\u662fFDA\u8fd1\u5e74\u6765\u6279\u51c6\u7684\u4e73\u5242\u4ea7\u54c1\uff0c\u6c2f\u7ef4\u5730\u5e73\u56e0\u53d1\u73b0\u91d1\u5c5e\u9897\u7c92\u7684\u95ee\u9898\u4f7f\u7528\u5df2\u7ecf\u5f88\u5c11\uff0c\u9500\u552e\u989d\u59cb\u7ec8\u6ca1\u6709\u8d85\u8fc70.5\u4ebf\u7f8e\u5143\u3002\u963f\u745e\u5339\u5766\u662f2017\u5e74\u521a\u521a\u83b7\u6279\uff0c\u5e02\u573a\u6548\u76ca\u8fd8\u6ca1\u6709\u53d1\u6325\u51fa\u6765\uff0c\u4f46\u62e5\u6709\u5de8\u5927\u7684\u53d1\u5c55\u6f5c\u529b\u3002<\/span><\/p>\n<p style=\"text-align: justify;\"><br  \/><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 15px;\"><span style=\"font-size: 15px;text-align: justify;\">\u5728\u8fc7\u53bb\u768410\u5e74\u91cc\uff0c\u6211\u56fd\u7684\u6ce8\u5c04\u4e73\u5242\u5e02\u573a\u9ad8\u901f\u53d1\u5c55\uff0c\u9500\u552e\u989d\u7ffb\u4e86\u4e09\u7ffb\uff0c2017\u5e74\u6211\u56fd\u7684\u4e73\u5242\u5e02\u573a\u8fbe110\u4ebf\u5143\uff0c\u5360\u636e\u5168\u7403\u7684\u4e00\u534a\u3002<\/span>\u5728\u56fd\u5bb6\u4e25\u683c\u63a7\u5236\u533b\u7597\u652f\u51fa\u7684\u5927\u73af\u5883\u4e0b\uff0c\u524d\u5217\u5730\u5c14\u9500\u552e\u989d\u7ee7\u7eed\u4e0a\u6da8\u7684\u53ef\u80fd\u4e0d\u5927\uff0c\u4e19\u6cca\u915a\u53ef\u80fd\u4f1a\u5c0f\u5e45\u4e0a\u6da8\uff0c\u6c2f\u7ef4\u5730\u5e73\u548c\u963f\u745e\u5339\u5766\u53ef\u80fd\u662f\u4e73\u5242\u5382\u5bb6\u7684\u5fc5\u4e89\u4e4b\u5730\u3002<span style=\"font-size: 15px;text-align: justify;\">\u4e2d\u56fd\u7684\u8102\u80aa\u4e73\u4ea7\u4e1a\u94fe\u53d1\u5c55\u5df2\u7ecf\u975e\u5e38\u6210\u719f\uff0c\u4e73\u5242\u7684\u5e02\u573a\u51e0\u8fd1\u9971\u548c\uff0c\u5df2\u7ecf\u4e0d\u9002\u4e8e\u65b0\u5165\u95e8\u4f01\u4e1a\u5e03\u5c40\u3002<\/span><\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"text-align: justify;\"><br  \/><\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"text-align: justify;\"><\/span><\/p>\n<section class=\"RankEditor\" style=\"margin-right: auto;margin-left: auto;border-width: 0px;border-style: none;border-color: initial;margin-top: 20px;\">\n<section style=\"width: 0.6em;display: inline-block;vertical-align: middle;\"><span style=\"width: 0.6em;height: 0.6em;display: block;opacity: 0.2;color: rgb(255, 255, 255);background-color: rgb(214, 0, 74);\"><\/span><span style=\"color: rgb(192, 0, 0);\"><span style=\"margin-top: 2px;margin-bottom: 2px;width: 0.6em;height: 0.6em;display: block;opacity: 0.6;color: rgb(255, 255, 255);background-color: rgb(214, 0, 74);\"><\/span><span style=\"width: 0.6em;height: 0.6em;display: block;opacity: 1;color: rgb(255, 255, 255);background-color: rgb(214, 0, 74);\"><\/span><\/span><\/section>\n<section style=\"padding-left: 10px;display: inline-block;vertical-align: middle;font-weight: 700;color: rgb(214, 0, 74);\">\n<section class=\"active brush\"><span style=\"color: rgb(192, 0, 0);\">\u7b2c\u4e8c\u90e8\u5206 \u6ce8\u5c04\u8102\u8d28\u4f53<\/span><\/section>\n<\/section>\n<\/section>\n<p style=\"text-align: justify;\"><span style=\"text-align: justify;\"><\/span><\/p>\n<p style=\"text-align: center;\"><br  \/><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 15px;\">\u5728\u836f\u5242\u5b66\u4e0a\uff0c\u8102\u8d28\u4f53\u6307\u5c06\u836f\u7269\u5305\u5c01\u4e8e\u7c7b\u8102\u8d28\u53cc\u5206\u5b50\u5c42\u5185\u800c\u5f62\u6210\u7684\u5fae\u578b\u6ce1\u56ca\u4f53\u3002\u7531\u4e8e\u8102\u8d28\u4f53\u5177\u6709\u5f88\u5f3a\u7684\u589e\u6eb6\u80fd\u529b\uff0c\u56e0\u6b64\u8102\u8d28\u4f53\u4e5f\u662f\u4e00\u79cd\u96be\u6eb6\u6027\u836f\u7269\u7684\u589e\u6eb6\u7b56\u7565\uff0c\u9664\u6b64\u4ee5\u5916\uff0c\u8102\u8d28\u4f53\u72ec\u7279\u7684\u91ca\u836f\u673a\u5236\uff0c\u8d4b\u4e88\u4e86\u8102\u8d28\u4f53\u7f13\u91ca\u6216\u9776\u5411\u7684\u751f\u7269\u836f\u5242\u5b66\u7279\u6027\uff0c\u4e5f\u662f\u8102\u8d28\u4f53\u53d7\u7814\u53d1\u4eba\u5458\u7684\u9752\u7750\u7684\u4e00\u5927\u539f\u56e0\u3002<\/span><\/p>\n<p style=\"text-align: justify;\"><br  \/><\/p>\n<p style=\"text-align: center;\"><span style=\"text-align: justify;\"><\/span><\/p>\n<p style=\"white-space: normal;max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);text-align: center;\">\u5168\u7403\u8303\u56f4\u5185\u83b7\u6279\u4e0a\u5e02\u7684\u8102\u8d28\u4f53\uff08\u4e0d\u542b\u75ab\u82d7\uff09<span style=\"letter-spacing: 0.544px;\"><\/span><\/p>\n<p style=\"white-space: normal;\"><img class=\"\"         style=\"width: 100%;height: auto;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/08\/beepress3-1533691021.jpg\" alt=\"\u590d\u6742\u6ce8\u5c04\u5242\u7684\u5e02\u573a\u6982\u51b5\u548c\u53d1\u5c55\u673a\u9047\" title=\"\u590d\u6742\u6ce8\u5c04\u5242\u7684\u5e02\u573a\u6982\u51b5\u548c\u53d1\u5c55\u673a\u9047\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 15px;\">\u5230\u76ee\u524d\u4e3a\u6b62\uff0c\u5168\u7403\u5df2\u7ecf\u6709\u5341\u4f59\u4e2a\u6ce8\u5c04\u8102\u8d28\u4f53\u4ea7\u54c1\u83b7\u6279\u4e0a\u5e02\uff0c\u5176\u4e2d\u4ea7\u54c1\u6700\u591a\u7684\u662f\u7ec6\u80de\u6bd2\u7c7b\u6297\u764c\u836f\u4f9d\u7acb\u66ff\u5eb7\u3001\u591a\u67d4\u6bd4\u661f\u3001\u963f\u7cd6\u80de\u82f7\u3001\u67d4\u7ea2\u9709\u7d20\u3001\u957f\u6625\u65b0\u78b1\u548c\u7d2b\u6749\u9187\u7b49\uff0c\u9664\u6b64\u4ee5\u5916\uff0c\u6210\u529f\u7684\u8102\u8d28\u4f53\u4ea7\u54c1\u8fd8\u5305\u62ec\u9547\u75db\u836f\u5417\u5561\uff0c\u9ebb\u9189\u836f\u5e03\u6bd4\u5361\u56e0\uff0c\u6297\u771f\u83cc\u836f\u4e24\u6027\u9709\u7d20B\u7b49\u3002\u5728\u8fc7\u53bb\u76845\u5e74\u91cc\uff0c\u5168\u7403\u8102\u8d28\u4f53\u5e02\u573a\u589e\u957f\u4e86\u7ea640%\uff0c2017\u5e74\u7684\u8102\u8d28\u4f53\u5e02\u573a\u89c4\u6a21\u5df2\u7ecf\u8fbe\u523014\u4ebf\u7f8e\u5143\u3002\u8fd1\u5e74\u6765\uff0c\u6211\u56fd\u7684\u8102\u8d28\u4f53\u5e02\u573a\u53d1\u5c55\u4e5f\u6bd4\u8f83\u5feb\uff0c\u603b\u9500\u552e\u989d\u8fd125\u4ebf\u5143\u4eba\u6c11\u5e01\u3002<\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);text-align: center;\"><br  \/><\/p>\n<p><img class=\"\"          style=\"width: 100%;height: auto;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/08\/beepress6-1533691021.jpeg\" alt=\"\u590d\u6742\u6ce8\u5c04\u5242\u7684\u5e02\u573a\u6982\u51b5\u548c\u53d1\u5c55\u673a\u9047\" title=\"\u590d\u6742\u6ce8\u5c04\u5242\u7684\u5e02\u573a\u6982\u51b5\u548c\u53d1\u5c55\u673a\u9047\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><span style=\"letter-spacing: 0.544px;\"><\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 15px;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-family: \u5b8b\u4f53;box-sizing: border-box !important;word-wrap: break-word !important;\">\u591a\u67d4\u6bd4\u661f\u8102\u8d28\u4f53 <\/span><\/strong>\u5168\u7403\u8303\u56f4\u5185\uff0c\u9500\u552e\u989d\u6700\u9ad8\u7684\u8102\u8d28\u4f53\u662f\u591a\u67d4\u6bd4\u661f\u3002\u5236\u5907\u6210\u8102\u8d28\u4f53\u540e\uff0c\u4e0d\u4f46\u6539\u5584\u4e86\u591a\u67d4\u6bd4\u661f\u7684\u7597\u6548\uff0c\u8fd8\u80fd\u5927\u5e45\u964d\u4f4e\u591a\u67d4\u6bd4\u661f\u7684\u5fc3\u810f\u6bd2\u6027\u3002\u591a\u67d4\u6bd4\u661f\u8102\u8d28\u4f53\u4e2d\uff0cALZA\u5f00\u53d1\u7684Doxil\/Caelyx\u662f\u6700\u6210\u529f\u7684\uff0c\u6700\u9ad8\u9500\u552e\u989d\u8d85\u8fc76\u4ebf\u7f8e\u5143\u3002<span style=\"font-size: 15px;text-align: justify;\">Caelyx\u662f<\/span>\u7ecf\u8fc7PEG\u4fee\u9970\u540e\u7684\u8102\u8d28\u4f53\uff0c\u4e3b\u8981\u5206\u5e03\u4e8e\u76ae\u80a4\u8868\u5c42\uff0c\u56e0\u6b64<span style=\"font-size: 15px;text-align: justify;\">Caelyx<\/span>\u53ef\u4ee5\u7528\u4e8e\u5361\u6ce2\u6c0f\u8089\u7624\u7684\u6cbb\u7597\u3002Elan\u516c\u53f8\u5f00\u53d1\u7684Myocet\u56e0\u4e3a\u6ca1\u6709\u7ecf\u8fc7PEG\u4fee\u9970\uff0c\u5b83\u7684\u5206\u5e03\u7279\u5f81\u4e0eDoxil\u663e\u8457\u4e0d\u540c\uff0c\u53ea\u80fd\u7528\u4e8e\u4e73\u817a\u764c\u6216\u767d\u8840\u75c5\u7b49\u3002\u9664\u4e86\u4ee5\u4e0a\u4e24\u4e2a\u4ee3\u8868\u6027\u4ea7\u54c1\uff0c\u56fd\u5185\u4e5f\u6709\u591a\u67d4\u6bd4\u661f\u8102\u8d28\u4f53\u83b7\u6279\uff0c\u5176\u4e2d\u590d\u65e6\u5f20\u6c5f\u7684\u91cc\u8446\u591a\u5e74\u9500\u552e\u989d\u4e00\u5ea6\u8fbe\u52305.5\u4ebf\u5143\uff0c\u800c\u77f3\u836f\u7684\u8102\u8d28\u4f53\u4e5f\u5f00\u59cb\u653e\u91cf\uff0cIMS\u6570\u636e\u663e\u793a\uff0c\u591a\u7f8e\u7d202017\u5e74\u7684\u9500\u552e\u989d\u5df2\u7ecf\u8fbe\u52303600\u4e07\u7f8e\u5143\u3002<\/span><\/p>\n<p style=\"text-align: justify;\"><br  \/><\/p>\n<p style=\"text-align: justify;\"><img class=\"\"        style=\"color: rgb(51, 51, 51);text-align: center;white-space: normal;width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;visibility: visible !important;height: auto;\"   src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/08\/beepress1-1533691021.jpeg\" alt=\"\u590d\u6742\u6ce8\u5c04\u5242\u7684\u5e02\u573a\u6982\u51b5\u548c\u53d1\u5c55\u673a\u9047\" title=\"\u590d\u6742\u6ce8\u5c04\u5242\u7684\u5e02\u573a\u6982\u51b5\u548c\u53d1\u5c55\u673a\u9047\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><span style=\"letter-spacing: 0.544px;\"><\/span><br  \/><\/p>\n<p style=\"text-align: justify;\"><strong><span style=\"font-size: 15px;\">\u4e24\u6027\u9709\u7d20B\u8102\u8d28\u4f53<\/span><\/strong><span style=\"font-size: 15px;\">&nbsp;\u4e24\u6027\u9709\u7d20B\u662f\u6df1\u5ea6\u771f\u83cc\u611f\u67d3\u7684\u9996\u9009\u836f\uff0c\u4f46\u5176\u80be\u6bd2\u6027\u8ba9\u533b\u751f\u53c8\u7231\u53c8\u6068\u3002\u4e24\u6027\u9709\u7d20\u8102\u8d28\u4f53B\u5f88\u5927\u7a0b\u5ea6\u662f\u89e3\u51b3\u4e86\u8fd9\u4e00\u95ee\u9898\uff0c\u4e24\u6027\u9709\u7d20B\u8102\u8d28\u4f53\u6700\u65e9\u7531Nexstar\u516c\u53f8\u5f00\u53d1\uff0c\u5546\u54c1\u540d\u4e3aAmbisome\uff0c\u540e\u6765Nexstar\u88ab\u5409\u5229\u5fb7\u6536\u8d2d\uff0c\u4ea7\u54c1\u5f52\u5165\u5409\u5229\u5fb7\u3002\u5e02\u573a\u65b9\u9762\uff0c\u4e24\u6027\u9709\u7d20B\u8102\u8d28\u4f53\u4e3b\u8981\u7531\u5409\u5229\u5fb7\u3001\u5b89\u65af\u6cf0\u6765\u548c\u4f4f\u53cb\u5171\u540c\u9500\u552e\uff0c\u9500\u552e\u989d\u4ece2009\u5e74\u81f32015\u5e74\u90fd\u7ef4\u6301\u57284\u4ebf\u7f8e\u5143\u5de6\u53f3\u3002\u56fd\u5185\u65b9\u9762\uff0c\u4ec5\u4e0a\u6d77\u4e0a\u836f\u65b0\u4e9a\u836f\u4e1a\u6709\u9650\u516c\u53f8\u83b7\u6279\uff0c\u5546\u54c1\u540d\u4e3a\u950b\u514b\u677e\u3002\u4e0e\u56fd\u9645\u5e02\u573a\u884c\u60c5\u4e0d\u540c\u7684\u662f\uff0c\u4e24\u6027\u9709\u7d20B\u5df2\u7ecf\u5b8c\u5168\u88ab\u8fb9\u7f18\u5316\uff0c\u5168\u5e74\u9500\u552e\u989d\u4ec54000\u4e07\u4eba\u6c11\u5e01\u5de6\u53f3\u3002<\/span><\/p>\n<p><br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/p>\n<p style=\"text-align: justify;\"><strong><span style=\"font-size: 15px;\">\u7d2b\u6749\u9187\u8102\u8d28\u4f53<\/span><\/strong><span style=\"font-size: 15px;\">&nbsp;\u7d2b\u6749\u9187\u8102\u8d28\u4f53\u662f\u6211\u56fd\u9996\u521b\u4ea7\u54c1\uff0c\u7531\u5357\u4eac\u7eff\u53f6\u5f00\u53d1\u9500\u552e\uff0c\u5546\u54c1\u540d\u4e3a\u529b\u6251\u7d20\uff0c\u4e8e2003\u5e74\u83b7\u6279\u4e0a\u5e02\u3002\u529b\u6251\u7d20\u6210\u529f\u89e3\u51b3\u4e86\u7d2b\u6749\u9187\u6eb6\u89e3\u5ea6\u4f4e\u7684\u95ee\u9898\uff0c\u89e3\u9664\u6eb6\u5a92\u5f15\u8d77\u7684\u8d85\u654f\u98ce\u9669\uff0c\u660e\u663e\u964d\u4f4e\u4e86\u7d2b\u6749\u9187\u7684\u6bd2\u526f\u4f5c\u7528\uff0c\u63d0\u9ad8\u4e86\u60a3\u8005\u4f9d\u4ece\u6027\u3002\u5e02\u573a\u65b9\u9762\u529b\u6251\u7d20\u83b7\u5f97\u5f88\u5927\u7684\u6210\u529f\u30022010\u5e74\u4ee5\u540e\uff0c\u9500\u552e\u989d\u9ad8\u901f\u589e\u957f\uff0c2013\u5e74\u7684\u9500\u552e\u989d\u4e3a8.5\u4ebf\u5143\uff0c&nbsp;2017\u5e74\u7684\u9500\u552e\u989d\u6ca1\u6709\u516c\u5e03\uff0c\u4f30\u8ba1\u572822\u4ebf\u5143\u5de6\u53f3\u3002<\/span><\/p>\n<p><br  \/><\/p>\n<p style=\"text-align: justify;\"><strong><span style=\"font-size: 15px;\">\u5e03\u6bd4\u5361\u56e0\u8102\u8d28\u4f53<\/span><\/strong><span style=\"font-size: 15px;\">&nbsp;\u5e03\u6bd4\u5361\u56e0\u8102\u8d28\u4f53\u7531Pacira\u9500\u552e\uff0c\u5546\u54c1\u540d\u4e3aExparel\uff0c2012\u5e74\u83b7\u5f97FDA\u6279\u51c6\u4e0a\u5e02\u3002Exparel\u662f\u4e00\u79cd\u4f7f\u7528DepoFoam\u6280\u672f\u5236\u5907\u7684\u591a\u5ba4\u8102\u8d28\u4f53\uff0c\u7528\u4e8e\u672f\u540e\u6b62\u75db\uff0c\u9547\u75db\u6548\u679c\u53ef\u7ef4\u630172\u5c0f\u65f6\u3002\u5e02\u573a\u65b9\u9762\uff0cExparel\u53d6\u5f97\u4e86\u5f88\u5927\u6210\u529f\uff0c2017\u5e74\u9500\u552e\u989d\u5df2\u8fbe2.4\u4ebf\u7f8e\u5143\u3002\u57282012\u5e74\u4e4b\u524d\uff0cPacira\u8fd8\u662f\u4e00\u4e2a\u5e74\u9500\u552e\u989d\u53ea\u6709\u51e0\u767e\u4e07\u7f8e\u5143\u7684\u5c0f\u516c\u53f8\uff0c\u5e03\u6bd4\u5361\u56e0\u8102\u8d28\u4f53\u7684\u6210\u529f\uff0c\u4f7fPacira\u7684\u9500\u552e\u989d\u7ffb\u4e86100\u500d\u3002\u9664\u4e86\u5e03\u6bd4\u5361\u56e0\u8102\u8d28\u4f53\uff0c\u8be5\u516c\u53f8\u4f7f\u7528DepoFoam\u6280\u672f\u751f\u4ea7\u7684\u8102\u8d28\u4f53\u8fd8\u5305\u62ec\u5417\u5561\u8102\u8d28\u4f53\uff08\u64a4\u5e02\uff09\u548c\u963f\u7cd6\u80de\u82f7\u8102\u8d28\u4f53\u3002<\/span><\/p>\n<p><br  \/><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 15px;\">\u8102\u8d28\u4f53\u8f7d\u836f\u7cfb\u7edf\u4f18\u826f\u7684\u751f\u7269\u836f\u5242\u5b66\u7279\u6027\u662f\u672a\u6765\u6700\u6709\u6f5c\u529b\u7684\u5242\u578b\u4e4b\u4e00\uff0cVyxeos\uff08\u963f\u7cd6\u80de\u82f7+\u67d4\u7ea2\u9709\u7d20\uff09\u548cArikayce\uff08\u963f\u7c73\u5361\u661f\uff09\u88abFDA\u6388\u4e88\u7a81\u7834\u6027\u7597\u6cd5\u5c31\u662f\u6700\u597d\u7684\u4f8b\u8bc1\u3002\u4e34\u5e8a\u8bd5\u9a8c\u663e\u793aVyxeos\u6cbb\u7597\u7ec4\u4e2d\u4f4d\u751f\u5b58\u65f6\u95f4\u4e3a9.6\u4e2a\u6708\uff0c\u800c\u6807\u51c6\u7684\u963f\u7cd6\u80de\u82f7+\u67d4\u7ea2\u9709\u7d20\u7ec4\u4ec55.9\u4e2a\u6708\u3002Vyxeos\u5df2\u7ecf\u4e8e2017\u5e74\u83b7\u6279\uff0c\u800c\u4e14\u5df2\u7ecf\u5f00\u59cb\u653e\u91cf\uff0c\u5b83\u53ef\u80fd\u662f\u4e0b\u4e00\u4e2a\u5e74\u9500\u552e\u989d\u8d85\u8fc71\u4ebf\u7f8e\u5143\u7684\u8102\u8d28\u4f53\u4ea7\u54c1\u3002<\/span><\/p>\n<p><br  \/><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 15px;\">\u867d\u7136\u6211\u56fd\u4e0a\u5e02\u7684\u8102\u8d28\u4f53\u4ea7\u54c1\u4e0d\u591a\uff0c\u4f46\u662f\u4e2d\u56fd\u7684\u8102\u8d28\u4f53\u5e02\u573a\u5df2\u7ecf\u5360\u5230\u5168\u7403\u768422%\uff0c\u8fd1\u5e74\u6765\u6211\u56fd\u7684\u8102\u8d28\u4f53\u7533\u62a5\u6570\u91cf\u660e\u663e\u589e\u591a\uff0c\u8102\u8d28\u4f53\u5e02\u573a\u6bd4\u8f83\u8fdb\u4e00\u6b65\u589e\u52a0\uff0c2025\u5e74\u6709\u671b\u8fbe\u523040\u4ebf\u4eba\u6c11\u5e01\u3002\u5c3d\u7ba1\u5982\u6b64\uff0c\u6211\u56fd\u7684\u8102\u8d28\u4f53\u4e0e\u7f8e\u56fd\u4ecd\u5b58\u5728\u5f88\u5927\u7684\u5dee\u8ddd\uff0c\u5176\u4e2d\u8f85\u6599\u548c\u8bbe\u5907\u662f\u6211\u56fd\u8102\u8d28\u4f53\u4ea7\u4e1a\u53d1\u5c55\u7684\u4e3b\u8981\u95e8\u69db\u3002<\/span><br  \/><\/p>\n<p style=\"text-align: justify;\"><br  \/><\/p>\n<section class=\"RankEditor\" style=\"margin-right: auto;margin-left: auto;border-width: 0px;border-style: none;border-color: initial;margin-top: 20px;\">\n<section style=\"width: 0.6em;display: inline-block;vertical-align: middle;\"><span style=\"width: 0.6em;height: 0.6em;display: block;opacity: 0.2;color: rgb(255, 255, 255);background-color: rgb(214, 0, 74);\"><\/span><span style=\"color: rgb(192, 0, 0);\"><span style=\"margin-top: 2px;margin-bottom: 2px;width: 0.6em;height: 0.6em;display: block;opacity: 0.6;color: rgb(255, 255, 255);background-color: rgb(214, 0, 74);\"><\/span><span style=\"width: 0.6em;height: 0.6em;display: block;opacity: 1;color: rgb(255, 255, 255);background-color: rgb(214, 0, 74);\"><\/span><\/span><\/section>\n<section style=\"padding-left: 10px;display: inline-block;vertical-align: middle;font-weight: 700;color: rgb(214, 0, 74);\">\n<section class=\"active brush\"><span style=\"color: rgb(192, 0, 0);\">\u7b2c\u4e09\u90e8\u5206 \u6ce8\u5c04\u5fae\u7403<\/span><\/section>\n<\/section>\n<\/section>\n<p style=\"text-align: justify;\"><br  \/><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 15px;\">\u836f\u5242\u5b66\u4e0a\u5c06\u5fae\u7403\u5b9a\u4e49\u4e3a\u836f\u7269\u6eb6\u89e3\u6216\u5206\u6563\u4e8e\u9ad8\u5206\u5b50\u6750\u6599\u4e2d\u6240\u5f62\u6210\u7684\u5fae\u5c0f\u7403\u4f53\u6216\u7c7b\u7403\u4f53\uff0c\u7c92\u5f84\u901a\u5e38\u57281-300\u03bcm\u4e4b\u95f4\uff0c\u5e38\u89c1\u7684\u6ce8\u5c04\u5fae\u7403\u5305\u62ec\u8102\u8d28\u5fae\u7403\u548c\u805a\u4e59\u4ea4\u916f-\u4e19\u4ea4\u916f\u5171\u805a\u7269\uff08poly lactic-co-glycolic acid\uff0cPLGA\uff09\u5fae\u7403\uff0c<span style=\"text-align: justify;\">\u8102\u8d28\u5fae\u7403\u7c7b\u4f3c\u4e8e\u51bb\u5e72\u4e73\u5242\uff0c\u4e3b\u8981\u4ea7\u54c1\u662f\u8d85\u58f0\u9020\u5f71\u5242\uff0c\u800cPLGA\u5fae\u7403\u5177\u6709\u5f3a\u5927\u7684\u7f13\u91ca\u4f5c\u7528\uff0c\u76ee\u524d\u5df2\u7ecf\u5b9e\u73b0\u4e86\u6bcf6\u4e2a\u6708\u4e00\u6b21\u7684\u8d85\u957f\u6548\u7ed9\u836f\u3002<\/span><\/span><\/p>\n<p style=\"text-align: justify;\"><br  \/><\/p>\n<p style=\"text-align: center;\">FDA\u6279\u51c6\u7684\u5fae\u7403\u4ea7\u54c1<\/p>\n<p><img class=\"\"         style=\"width: 100%;height: auto;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/08\/beepress6-1533691022.jpg\" alt=\"\u590d\u6742\u6ce8\u5c04\u5242\u7684\u5e02\u573a\u6982\u51b5\u548c\u53d1\u5c55\u673a\u9047\" title=\"\u590d\u6742\u6ce8\u5c04\u5242\u7684\u5e02\u573a\u6982\u51b5\u548c\u53d1\u5c55\u673a\u9047\"  \/><\/p>\n<p><br  \/><\/p>\n<p style=\"white-space: normal;text-align: justify;\"><span style=\"font-size: 15px;\"><span style=\"text-align: justify;\">\u56e0PLGA\u5fae\u7403\u6ce8\u53ef\u5ef6\u957f\u836f\u7269\u7684\u4f5c\u7528\u65f6\u95f4\u3001\u51cf\u5c11\u7528\u836f\u6b21\u6570\u3001\u6539\u5584\u60a3\u8005\u7684\u987a\u5e94\u6027\u7684\u4f18\u70b9\uff0c\u5df2\u6210\u4e3a\u7f13\u91ca\u6ce8\u5c04\u5242\u7814\u53d1\u7684\u9ad8\u5927\u4e0a\u3002<\/span>\u622a\u6b62\u76ee\u524d\uff0c\u5168\u7403\u5df2\u6709\u8fd1\u5341\u4e2aPLGA\u5fae\u7403\u4e0a\u5e02\uff0c\u4ea7\u54c1\u4e3b\u8981\u662f\u591a\u80bd\u548c\u7cbe\u795e\u7c7b\u836f\u7269\u3002\u5c3d\u7ba1\u4ea7\u54c1\u4e0d\u591a\uff0c\u4f46PLGA\u5fae\u7403\u5de8\u5927\u7684\u4e34\u5e8a\u4f18\u52bf\u51b3\u5b9a\u4e86\u5b83\u7684\u5e02\u573a\u4ef7\u503c\uff0c2017\u5e74\u5168\u7403PLGA\u5fae\u7403\u7684\u5e02\u573a\u5df2\u7ecf\u8d85\u8fc765\u4ebf\u7f8e\u5143\uff0c\u867d\u7136\u4e2d\u56fd\u8d77\u70b9\u6bd4\u8f83\u4f4e\uff0c\u4f46\u53d1\u5c55\u901f\u5ea6\u975e\u5e38\u5feb\uff0c2017\u5e74\uff0c\u6211\u56fd\u7684\u6ce8\u5c04\u5fae\u7403\u5e02\u573a\u5df2\u7ecf\u5360\u5230\u5168\u7403\u76844.5%\u3002<\/span><\/p>\n<p><br  \/><\/p>\n<p><img class=\"\"          style=\"width: 100%;height: auto;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/08\/beepress6-1533691022.jpeg\" alt=\"\u590d\u6742\u6ce8\u5c04\u5242\u7684\u5e02\u573a\u6982\u51b5\u548c\u53d1\u5c55\u673a\u9047\" title=\"\u590d\u6742\u6ce8\u5c04\u5242\u7684\u5e02\u573a\u6982\u51b5\u548c\u53d1\u5c55\u673a\u9047\"  \/><\/p>\n<p><br  \/><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 15px;\"><strong style=\"color: rgb(51, 51, 51);white-space: normal;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\">\u4eae\u4e19\u745e\u6797\u5fae\u7403<\/strong><span class=\"Apple-converted-space\" style=\"font-size: 15px;color: rgb(51, 51, 51);\">&nbsp;&nbsp; <\/span>\u4eae\u4e19\u745e\u6797\u5fae\u7403\u6700\u65e9\u7531\u6b66\u7530\u5f00\u53d1\uff0c\u5168\u7403\u8303\u56f4\u5185\u7531\u6b66\u7530\u3001\u827e\u4f2f\u7ef4\u548cOrion\u5171\u540c\u9500\u552e\uff0c\u5546\u54c1\u540d\u5206\u522b\u4e3a\u6291\u90a3\u901a\u6216Lupron 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style=\"text-align: justify;\"><br  \/><\/p>\n<p style=\"text-align: justify;\"><strong><span style=\"font-size: 15px;\">\u66f2\u666e\u745e\u6797\u5fae\u7403<\/span><\/strong><span style=\"font-size: 15px;\">&nbsp; \u66f2\u666e\u745e\u6797\u5fae\u7403\u7531Debio 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15px;\">\u591a\u80bd\u836f\u7269\u5927\u591a\u751f\u7269\u534a\u8870\u671f\u8f83\u77ed\uff0c\u800c\u4e14\u53ea\u80fd\u6ce8\u5c04\u7ed9\u836f\uff0c\u987a\u5e94\u6027\u65b9\u9762\u5b58\u5728\u7740\u5f88\u5927\u7684\u95ee\u9898\uff0c\u6ce8\u5c04\u5fae\u7403\u662f\u6700\u4e3b\u8981\u7684\u89e3\u51b3\u624b\u6bb5\u4e4b\u4e00\u3002\u9664\u6b64\u4e4b\u5916\uff0c\u5bf9\u4e8e\u4e00\u4e9b\u7cbe\u795e\u7c7b\u836f\u54c1\uff0c\u5236\u6210\u7f13\u91ca\u5fae\u7403\uff0c\u53ef\u4ee5\u89e3\u51b3\u7528\u836f\u7684\u56f0\u96be\u6216\u836f\u54c1\u7684\u6ee5\u7528\u95ee\u9898\u3002\u4ece\u7b2c\u4e00\u4e2a\u5fae\u7403\u4ea7\u54c1\u8bde\u751f\u81f3\u4eca\u5df2\u8fd130\u8f7d\uff0c11\u4e2a\u5fae\u7403\u836f\u7269\u83b7FDA\u6279\u51c6\u4e0a\u5e02\uff0c\u5176\u4e2d\u5965\u66f2\u80bd\u3001\u4eae\u4e19\u745e\u6797\u3001\u66f2\u666e\u745e\u6797\u3001\u5229\u57f9\u916e\u548c\u7eb3\u66f2\u916e\u7b495\u4e2a\u4ea7\u54c1\u4e0a\u5e02\u65f6\u95f4\u8d85\u8fc75\u5e74\uff0c\u8fd9\u4e9b\u4ea7\u54c1\u57282011\u5e74-2015\u5e74\u7684\u5e73\u5747\u7d2f\u8ba1\u9500\u552e\u989d\u4e3a24.3\u4ebf\u7f8e\u5143\uff0c\u5176\u4e2d\u5e73\u5747\u6bcf\u5e749.7\u4ebf\u7f8e\u5143\uff0c\u5e02\u573a\u6548\u5e94\u5df2\u4e0d\u4e9a\u4e8e\u65b0\u5206\u5b50\u5b9e\u4f53\u30022017\u5e74\uff0c\u5168\u7403PLGA\u5fae\u7403\u5e02\u573a\u5df2\u8fbe65.9\u4ebf\u7f8e\u5143\uff0c\u6211\u56fd\u7684\u5fae\u7403\u5e02\u573a\u6b63\u5904\u4e8e\u9ad8\u901f\u589e\u957f\u671f\uff0c2017\u5e74\u7684\u5e02\u573a\u89c4\u6a21\u5df2\u7ecf\u8fbe\u523020\u4ebf\u5143\u3002\u76ee\u524d\u6211\u56fd\u7684\u5fae\u7403\u5e02\u573a\u8fdc\u672a\u9971\u548c\uff0c\u6211\u56fd\u6709\u5168\u740320%\u7684\u4eba\u53e3\uff0c\u5374\u53ea\u5360\u636e\u4e86\u5168\u74034.5%\u7684\u5e02\u573a\uff0c\u56e0\u6b64\u672a\u6765\u51e0\u5e74\uff0c\u6211\u56fd\u7684\u5fae\u7403\u4ea7\u54c1\u5e02\u573a\u6f5c\u529b\u5de8\u5927\u3002\u5982\u679c\u6309\u5168\u7403\u4eba\u5747\u6d88\u8d39\u6c34\u5e73\u4f30\u7b97\uff0c\u6211\u56fd\u7684\u5fae\u7403\u5e02\u573a\u53ef\u8fbe70\u4ebf\u4eba\u6c11\u5e01\uff0c\u751a\u81f3\u66f4\u591a\u3002<\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><br  \/><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 15px;\">\u5fae\u7403\u5e02\u573a\u5de8\u5927\u7684\u53d1\u5c55\u6f5c\u529b\u662f\u8fd1\u5e74\u6765\u6211\u56fd\u5fae\u7403\u7814\u53d1\u6bd4\u8f83\u70ed\u95e8\u7684\u539f\u56e0\uff0c\u7136\u800c\u5168\u7403\u8303\u56f4\u5185\uff0c\u4e5f\u5c31\u90a3\u4e48\u4e09\u4e94\u5bb6\u516c\u53f8\u80fd\u591f\u751f\u4ea7\u5fae\u7403\uff0c\u56e0\u6b64\u5e76\u4e0d\u662f\u6240\u6709\u7684\u4f01\u4e1a\u90fd\u9002\u5408\u505a\u5fae\u7403\u3002\u9996\u5148\u662f\u6211\u56fd\u7684\u4eba\u624d\u7f3a\u4e4f\uff0c\u505a\u5fae\u7403\u7684\u4eba\u672c\u8eab\u5c31\u5c11\uff0c\u800c\u5168\u7403\u8303\u56f4\u5185\u6709\u5fae\u7403\u83b7FDA\u6279\u51c6\u7684\u5382\u5bb6\u4ec5\u6709\u6b66\u7530\u3001\u8bfa\u534e\u3001alkermers\u548cDebio\u7b49\uff0c\u6316\u4eba\u90fd\u96be\uff1b\u5176\u6b21\u662f\u5de5\u827a\u590d\u6742\uff0c\u63a7\u5236\u56f0\u96be\uff0c\u8bbe\u5907\u9700\u8981\u5b9a\u5236\uff0c\u751f\u4ea7\u8bbe\u5907\u9700\u8981\u5728\u957f\u671f\u7684\u751f\u4ea7\u4e2d\u4e0d\u65ad\u6539\u826f\uff1b\u518d\u6b21\u662f\u8d28\u91cf\u63a7\u5236\u56f0\u96be\uff0c\u7c92\u5ea6\u5206\u5e03\u3001\u8f7d\u836f\u91cf\u3001\u91ca\u836f\u901f\u7387\u3001\u7a81\u91ca\u95ee\u9898\uff0c\u65e0\u83cc\u5ea6\uff0c\u6b8b\u7559\u6eb6\u5242\u90fd\u662f\u5fae\u7403\u8d28\u91cf\u7684\u4e3b\u8981\u56e0\u7d20\uff1b\u6700\u540e\uff0c\u505a\u597d\u5fae\u7403\u8fd8\u9700\u89e3\u51b3\u4ea7\u80fd\u7684\u95ee\u9898\u3001\u8d28\u91cf\u4e00\u81f4\u6027\u7684\u95ee\u9898\u3001\u7ed9\u836f\u8bbe\u5907\u7684\u95ee\u9898\u3002\u5c3d\u7ba1\u4e2d\u56fd\u7684\u5df2\u7ecf\u6709\u56fd\u4ea7\u5fae\u7403\u4e0a\u5e02\uff0c\u4f46\u662f\u56fd\u4ea7\u5fae\u7403\u4e0e\u56fd\u9645\u5148\u8fdb\u6c34\u5e73\u8fd8\u6709\u4e00\u5b9a\u5dee\u8ddd\u3002<\/span><\/p>\n<p style=\"text-align: justify;\"><br  \/><\/p>\n<section class=\"RankEditor\" style=\"margin-right: auto;margin-left: auto;border-width: 0px;border-style: none;border-color: initial;margin-top: 20px;\">\n<section style=\"width: 0.6em;display: inline-block;vertical-align: middle;\"><span style=\"width: 0.6em;height: 0.6em;display: block;opacity: 0.2;color: rgb(255, 255, 255);background-color: rgb(214, 0, 74);\"><\/span><span style=\"color: rgb(192, 0, 0);\"><span style=\"margin-top: 2px;margin-bottom: 2px;width: 0.6em;height: 0.6em;display: block;opacity: 0.6;color: rgb(255, 255, 255);background-color: rgb(214, 0, 74);\"><\/span><span style=\"width: 0.6em;height: 0.6em;display: block;opacity: 1;color: rgb(255, 255, 255);background-color: rgb(214, 0, 74);\"><\/span><\/span><\/section>\n<section style=\"padding-left: 10px;display: inline-block;vertical-align: middle;font-weight: 700;color: rgb(214, 0, 74);\">\n<section class=\"active brush\"><span style=\"color: rgb(192, 0, 0);\">\u7b2c\u56db\u90e8\u5206 \u6ce8\u5c04\u6df7\u60ac\u6db2\u53ca\u5176\u5b83\u7f13\u91ca\u6ce8\u5c04\u5242<\/span><\/section>\n<\/section>\n<\/section>\n<p style=\"text-align: center;\"><br  \/><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 15px;\">\u6ce8\u5c04\u6df7\u60ac\u6db2\u5176\u5b9e\u5e76\u975e\u4f20\u7edf\u610f\u4e49\u4e0a\u7684\u6df7\u60ac\u6db2\uff0c\u800c\u662f\u4e00\u7c7b\u9ad8\u7aef\u5242\u578b\uff0c\u56e0\u4e3aFDA\u5728\u5242\u578b\u754c\u5b9a\u65f6\u628a\u5b83\u4eec\u53eb\u505a\u6df7\u60ac\u6db2\uff0c\u6240\u4ee5\u672c\u6587\u4e5f\u7edf\u4e00\u79f0\u4e4b\u4e3a\u6ce8\u5c04\u6df7\u60ac\u6db2\u3002\u622a\u6b62\u76ee\u524d\uff0cFDA\u6279\u51c6\u7684\u6ce8\u5c04\u6df7\u60ac\u6db2\u53ea\u670912\u4e2a\uff0c\u9664\u7eb3\u7c73\u6c27\u5316\u94c1\u548c\u7d2b\u6749\u9187\u4e4b\u5916\uff0c\u5176\u4f5910\u4e2a\u90fd\u662f\u7f13\u91ca\u6ce8\u5c04\u5242\uff0c\u5176\u4e2dEligard\u3001Sublocade\u548cAtridox\u662f\u901a\u8fc7PLGA\u6765\u8fbe\u6210\u7f13\u91ca\u7684\u76ee\u7684\uff0cSustol\u4f7f\u7528\u7684\u662f\u4e09\u7518\u9187\u805a\uff08\u539f\u9178\u916f\uff09\uff0c\u800c\u5e15\u5229\u54cc\u916e\u68d5\u6988\u9178\u916f\u548c\u963f\u7acb\u54cc\u5511\u6708\u6842\u9178\u916f\u662f\u901a\u8fc7\u5236\u5907\u96be\u6eb6\u6027\u76d0\u7684\u65b9\u5f0f\u6765\u5ef6\u7f13\u836f\u7269\u7684\u91ca\u653e\u3002<\/span><\/p>\n<p style=\"text-align: justify;\"><br  \/><\/p>\n<p style=\"text-align: center;\">FDA\u6279\u51c6\u7684\u6ce8\u5c04\u6df7\u60ac\u6db2\u4ea7\u54c1<\/p>\n<p><img class=\"\"         style=\"width: 100%;height: auto;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/08\/beepress7-1533691022.jpg\" alt=\"\u590d\u6742\u6ce8\u5c04\u5242\u7684\u5e02\u573a\u6982\u51b5\u548c\u53d1\u5c55\u673a\u9047\" title=\"\u590d\u6742\u6ce8\u5c04\u5242\u7684\u5e02\u573a\u6982\u51b5\u548c\u53d1\u5c55\u673a\u9047\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><span style=\"max-width: 100%;font-family: \u5b8b\u4f53;box-sizing: border-box !important;word-wrap: break-word !important;\"><\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 15px;\">\u6ce8\u5c04\u6df7\u60ac\u5242\u662f\u591a\u79cd\u5168\u65b0\u7684\u5242\u578b\uff0c\u56e0\u4e3a\u8fc7\u4e8e\u590d\u6742\uff0c\u6211\u56fd\u8fd8\u6ca1\u6709\u6ce8\u5c04\u6df7\u60ac\u5242\u4e0a\u5e02\u3002\u5c3d\u7ba1\u53ea\u6709\u5c48\u6307\u53ef\u6570\u7684\u51e0\u4e2a\u4ea7\u54c1\uff0c\u4f46\u5168\u7403\u5e02\u573a\u5df2\u7ecf\u8fbe\u523065\u4ebf\u7f8e\u5143\uff0c\u800c\u4e14\u8fd8\u5728\u8fdb\u4e00\u6b65\u9ad8\u901f\u589e\u957f\u4e2d\u3002\u56e0\u4e3a\u8fd1\u5e74\u6765\u6297\u7cbe\u795e\u75c5\u836f\u7269\u65b0\u836f\u532e\u4e4f\uff0c\u5f3a\u751f\u7684\u5e15\u5229\u54cc\u916e\u68d5\u6988\u9178\u916f\u9500\u552e\u989d\u6709\u671b\u8fdb\u4e00\u6b65\u4e0a\u6da8\uff0c\u6709\u671b\u8d85\u8fc730\u4ebf\u7f8e\u5143\uff0c\u800c\u963f\u7acb\u54cc\u5511\u7f13\u91ca\u6ce8\u5c04\u6db2\u4e5f\u662f\u975e\u5e38\u6709\u6f5c\u529b\u7684\u4ea7\u54c1\u3002\u9664\u6b64\u4ee5\u5916\uff0c\u6212\u6bd2\u836f\u4e01\u4e19\u8bfa\u5561\u7f13\u91ca\u6ce8\u5c04\u5242\u4e5f\u662f\u6765\u52bf\u6c79\u6c79\uff0c\u6839\u636e\u79d1\u777f\u552f\u5b89\u7684\u9884\u6d4b\uff0c\u8fd9\u4e5f\u662f\u4e00\u4e2a\u6709\u671b\u57285\u5e74\u5185\u5e74\u9500\u552e\u989d\u7a81\u783410\u4ebf\u7f8e\u5143\u7684\u4ea7\u54c1\u3002\u56e0\u6b64\u4e0d\u96be\u60f3\u8c61\uff0c\u5728\u672a\u6765\u7684\u4e94\u5e74\u91cc\uff0c\u5168\u7403\u6ce8\u5c04\u6df7\u60ac\u6db2\u7684\u5e02\u573a\u89c4\u6a21\u6709\u671b\u7a81\u783480\u4ebf\u7f8e\u5143\uff0c\u751a\u81f3\u5411100\u4ebf\u7f8e\u5143\u8fc8\u8fdb\u3002<\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><br  \/><\/p>\n<p><img class=\"\"          style=\"width: 100%;height: auto;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/08\/beepress8-1533691022.jpeg\" alt=\"\u590d\u6742\u6ce8\u5c04\u5242\u7684\u5e02\u573a\u6982\u51b5\u548c\u53d1\u5c55\u673a\u9047\" title=\"\u590d\u6742\u6ce8\u5c04\u5242\u7684\u5e02\u573a\u6982\u51b5\u548c\u53d1\u5c55\u673a\u9047\"  \/><\/p>\n<p><br  \/><\/p>\n<p style=\"white-space: normal;max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);text-align: justify;\"><span style=\"font-size: 15px;\"><strong>\u5e15\u5229\u54cc\u916e\u68d5\u6988\u9178\u916f<\/strong> \u5e15\u5229\u54cc\u916e\u662f\u5229\u57f9\u916e\u7684\u4ee3\u8c22\u7269\uff0c\u4e5f\u4f5c9-\u7f9f\u57fa\u5229\u57f9\u916e\uff0c\u76f8\u6bd4\u5229\u57f9\u916e\uff0c\u5e15\u5229\u54cc\u916e\u7684\u6d3b\u6027\u76f8\u5f53\uff0c\u4f46\u6cbb\u7597\u7a97\u66f4\u5bbd\u3002\u4f7f\u7528\u5e15\u5229\u54cc\u916e\u4e0e\u68d5\u6988\u9178\u6210\u916f\u53ef\u4ee5\u5927\u5e45\u964d\u4f4e\u836f\u7269\u7684\u6eb6\u89e3\u5ea6\uff0c\u4f7f\u5f97\u836f\u7269\u53ef\u4ee5\u5728\u8d85\u957f\u7684\u65f6\u95f4\u5185\u7f13\u6162\u91ca\u653e\u3002\u4e3a\u4e86\u63a7\u5236\u836f\u7269\u7684\u91ca\u653e\u901f\u5ea6\uff0c<span style=\"color: rgb(51, 51, 51);font-size: 15px;text-align: justify;\">Alkermes\u548c\u5f3a\u751f\u7684\u79d1\u5b66\u5bb6\u4f7f\u7528\u7eb3\u7c73\u6676\u6280\u672f\uff08nanocrystal TM\uff09\u5bf9\u836f\u7269\u7684\u7c92\u5f84\u8fdb\u884c\u4e25\u683c\u63a7\u5236\uff0c\u901a\u8fc7\u8868\u9762\u79ef\u6765\u53d8\u76f8\u63a7\u5236\u91ca\u836f\u901f\u5ea6\u3002<\/span><\/span><span style=\"font-size: 15px;\">\u6700\u65b0\u4e0a\u5e02\u7684\u5e15\u5229\u54cc\u916e\u7eb3\u7c73\u6676\u6df7\u60ac\u6db2\u6709\u6548\u65f6\u95f4\u53ef\u4ee5\u7ef4\u6301\u4e09\u4e2a\u6708\uff0c\u76f8\u6bd4\u5229\u57f9\u916e\u5fae\u7403\uff0c\u6301\u7eed\u65f6\u95f4\u66f4\u957f\u3002<\/span><span style=\"font-size: 15px;\">\u7eb3\u7c73\u6676\u6280\u672f\u53ef\u8c13\u662f\u8fd1\u5e74\u6765\u53d1\u5c55\u8d77\u6765\u7684\u6700\u6210\u529f\u5236\u5242\u6280\u672f\u4e4b\u4e00\uff0c\u8be5\u6280\u672f<\/span><span style=\"font-size: 15px;\">\u6700\u65e9\u7531Elan\u516c\u53f8\u5f00\u53d1\uff0c\u540e\u6765Alkermes\u6536\u8d2d\u4e86\u8be5\u6280\u672f\u5e73\u53f0\uff0c\u5e76\u5728\u6b64\u57fa\u7840\u4e0a\u8fdb\u884c\u4e00\u5b9a\u7684\u521b\u65b0\uff0c\u4f7f\u5f97<\/span><span style=\"font-size: 15px;\">Alkermes\u6e10\u6e10\u6210\u4e3a\u590d\u6742\u6ce8\u5c04\u5242\u9886\u57df\u7684\u4e00\u679d\u72ec\u79c0\uff0c\u9664\u4e86\u5e15\u5229\u54cc\u916e\u68d5\u6988\u9178\u916f\uff0c\u8be5\u516c\u53f8\u5f00\u53d1\u6216\u751f\u4ea7\u7684\u4ea7\u54c1\u8fd8\u5305\u62ec\u963f\u7acb\u54cc\u5511\u6708\u6842\u9178\u916f\u3001\u5229\u57f9\u916e\u5fae\u7403\u3001\u751f\u957f\u6fc0\u7d20\u5fae\u7403\u3001\u7eb3\u66f2\u916e\u5fae\u7403\u548c\u827e\u585e\u90a3\u80bd\u5fae\u7403\u7b49\u3002<\/span><\/p>\n<p style=\"white-space: normal;max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><span style=\"color: rgb(51, 51, 51);\"><br  \/><\/span><\/p>\n<p style=\"white-space: normal;max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);text-align: center;\"><span style=\"color: rgb(51, 51, 51);\">\u5f3a\u751f\u5bf9\u5229\u57f9\u916e\u7684\u5347\u7ea7\u8fc7\u7a0b<\/span><\/p>\n<p><img class=\"\"         style=\"width: 100%;height: auto;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/08\/beepress1-1533691023.jpg\" alt=\"\u590d\u6742\u6ce8\u5c04\u5242\u7684\u5e02\u573a\u6982\u51b5\u548c\u53d1\u5c55\u673a\u9047\" title=\"\u590d\u6742\u6ce8\u5c04\u5242\u7684\u5e02\u573a\u6982\u51b5\u548c\u53d1\u5c55\u673a\u9047\"  \/><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 15px;\"><strong>\u7d2b\u6749\u9187\u878d\u5408\u86cb\u767d<\/strong>&nbsp; \u4f17\u6240\u5468\u77e5\uff0c\u7d2b\u6749\u9187\u662f\u4e00\u79cd\u96be\u6eb6\u6027\u836f\u7269\uff0c\u6ce8\u5c04\u65f6\u9700\u8981\u4f7f\u7528\u6709\u673a\u6eb6\u5242\u52a9\u6eb6\uff0c\u6709\u673a\u6eb6\u5242\u4e0d\u4f46\u5177\u6709\u5f88\u5927\u7684\u523a\u6fc0\u6027\uff0c\u8fd8\u6709\u53ef\u80fd\u8bf1\u53d1\u8d85\u654f\u53cd\u5e94\u3002\u5728\u4e2d\u56fd\u4e0a\u5e02\u4e86\u7d2b\u6749\u9187\u8102\u8d28\u4f53\u7684\u540c\u65f6\uff0c\u7f8e\u56fd\u4e0a\u5e02\u4e86\u7d2b\u6749\u9187\u878d\u5408\u86cb\u767d\u3002Abraxane\u7531\u534e\u4eba\u79d1\u5b66\u5bb6\u9648\u9882\u96c4\u7684\u56e2\u961f\u7814\u53d1\uff0c\u4e0d\u4f46\u5f88\u597d\u5730\u89e3\u51b3\u4e86\u836f\u7269\u7684\u6eb6\u89e3\u6027\u95ee\u9898\uff0c\u800c\u4e14\u7597\u6548\u4e5f\u6709\u4e00\u5b9a\u5730\u589e\u5f3a\uff0c\u76f8\u6bd4\u8102\u8d28\u4f53\uff0c\u8be5\u4ea7\u54c1\u56e0\u4e0d\u542b\u78f7\u8102\uff0c\u800c\u4e0d\u4f1a\u53d1\u751f\u7531\u4e4b\u5e26\u6765\u7684\u6eb6\u8840\u53cd\u5e94\u3002Abraxane\u4e0a\u5e02\u540e\u5f97\u5230\u5e7f\u5927\u533b\u751f\u60a3\u8005\u7684\u8ba4\u53ef\uff0c\u5e74\u9500\u552e\u989d\u9ad8\u8fbe10\u4ebf\u7f8e\u5143\u3002<\/span><\/p>\n<p style=\"text-align: justify;\"><br  \/><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 15px;\"><strong>\u4e01\u4e19\u8bfa\u5561<\/strong> \u4e01\u4e19\u8bfa\u5561\u7f13\u91ca\u6ce8\u5c04\u5242Sublocade\u4e8e2017\u5e74\u5e95\u83b7\u5f97FDA\u6279\u51c6\uff0c\u662f\u4e00\u4e2a\u5177\u6709\u5212\u65f6\u4ee3\u610f\u4e49\u7684\u4ea7\u54c1\uff0c\u79d1\u777f\u552f\u5b89\u628a\u8be5\u4ea7\u54c1\u5217\u5165\u4e86\u300a2018\u5e74\u6700\u503c\u5f97\u5173\u6ce8\u7684\u65b0\u836f\u300b\u62a5\u544a\uff0c\u5e76\u9884\u6d4b\u8be5\u4ea7\u54c1\u57285\u5e74\u540e\u7684\u9500\u552e\u989d\u5c06\u8d85\u8fc710\u4ebf\u7f8e\u5143\u3002<span style=\"font-size: 15px;text-align: justify;\">Sublocade\u662f\u4e00\u79cd\u4f7f\u7528Atrix Lab\u516c\u53f8\u7684Atrigel\u6280\u672f\u5236\u5907\u7684\u4e00\u79cd\u7f13\u91ca\u6ce8\u5c04\u5242\uff0c\u8fd9\u662f\u4e00\u79cd\u542bPLGA\u548cN-\u7532\u57fa\u5421\u54af\u70f7\u916e\uff08\u52a9\u6eb6\u5242\uff09\u7684\u51dd\u80f6\u6db2\uff0c\u5f53\u51dd\u80f6\u6ce8\u5165\u4f53\u5185\u4e4b\u540e\uff0c\u56e0\u6eb6\u5242\u8fc5\u901f\u88ab\u673a\u4f53\u5438\u6536\u800c\u4f7f\u836f\u7269\u548cPLGA\u6790\u51fa\uff0c\u6790\u51fa\u7684\u836f\u7269\u88ab\u5305\u88f9\u5728PLGA\u4e4b\u4e2d\uff0c\u968f\u7740PLGA\u7684\u4e0d\u65ad\u964d\u89e3\uff0c\u518d\u7f13\u6162\u5730\u91ca\u653e\u51fa\u6765\u3002<\/span><\/span><span style=\"font-size: 15px;\">\u9664\u4e86<\/span><span style=\"font-size: 15px;\">Sublocade\uff0c\u4f7f\u7528\u8be5\u6280\u672f\u5236\u5907\u7684\u4ea7\u54c1\u8fd8\u6709\u4eae\u4e19\u745e\u6797\u7f13\u91ca\u6ce8\u5c04\u5242Eligard\uff0c\u591a\u897f\u73af\u7d20\u7f13\u91ca\u6ce8\u5c04\u5242Atridox\u7b49\uff0c\u5176\u4e2dEligard\u7684\u7f13\u91ca\u6548\u679c\u53ef\u4ee5\u4e0e\u4e3b\u6d41\u7684\u4eae\u4e19\u745e\u6797\u5fae\u7403\u5ab2\u7f8e\uff0c2017\u5e74\u603b\u9500\u552e\u989d\u4e3a2.9\u4ebf\u7f8e\u5143\u3002<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 15px;\"><span style=\"font-size: 15px;text-align: justify;\"><span style=\"font-size: 15px;text-align: justify;\"><br  \/><\/span><\/span><\/span><\/p>\n<p style=\"text-align: center;\"><span style=\"font-size: 15px;\"><span style=\"font-size: 15px;text-align: justify;\"><span style=\"font-size: 15px;text-align: justify;\">Atrigel\u6280\u672f\u793a\u610f\u56fe<\/span><\/span><\/span><\/p>\n<p style=\"text-align: center;\">\n<p style=\"text-align: center;\"><br  \/><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 15px;\"><span style=\"text-align: justify;\"><strong>\u963f\u7acb\u54cc\u5511&nbsp;<\/strong>&nbsp;FDA\u6279\u51c6\u7684\u963f\u7acb\u54cc\u5511\u7f13\u91ca\u6ce8\u5c04\u5242\u5305\u62ec\u5927\u51a2\u7684<\/span><span style=\"font-family: Arial;color: rgb(8, 8, 8);letter-spacing: 0.7px;\">A<\/span><span style=\"font-family: Arial;color: rgb(8, 8, 8);letter-spacing: -0.1px;\">b<\/span><span style=\"font-family: Arial;color: rgb(8, 8, 8);letter-spacing: 0px;\">ili<\/span><span style=\"font-family: Arial;color: rgb(8, 8, 8);letter-spacing: -0.7px;\">f<\/span><span style=\"font-family: Arial;color: rgb(8, 8, 8);letter-spacing: 0px;\">y&nbsp;<\/span><span style=\"font-family: Arial;color: rgb(8, 8, 8);letter-spacing: -0.47px;\">M<\/span><span style=\"font-family: Arial;color: rgb(8, 8, 8);letter-spacing: -0.1px;\">a<\/span><span style=\"font-family: Arial;color: rgb(8, 8, 8);letter-spacing: 0px;\">i<\/span><span style=\"font-family: Arial;color: rgb(8, 8, 8);letter-spacing: -0.1px;\">n<\/span><span style=\"font-family: Arial;color: rgb(8, 8, 8);letter-spacing: -0.7px;\">t<\/span><span style=\"font-family: Arial;color: rgb(8, 8, 8);letter-spacing: -0.1px;\">en<\/span><span style=\"font-family: Arial;color: rgb(8, 8, 8);letter-spacing: 0px;\">a\u548cAlkermes\u7684Aristada\uff0c\u524d\u8005\u7684\u6d3b\u6027\u7269\u8d28\u662f\u963f\u7acb\u54cc\u5511\uff0c\u540e\u8005\u662f\u963f\u7acb\u54cc\u5511\u6708\u6842\u9178\u916f\uff0c\u76f8\u6bd4\u524d\u8005\uff0c\u7ecf\u8fc7\u6210\u916f\u5904\u7406\u7684\u963f\u7acb\u54cc\u5511\u91ca\u653e\u65f6\u95f4\u66f4\u957f\uff0c\u53ef\u8fbe\u4e09\u4e2a\u6708\u3002\u5236\u5907\u5de5\u827a\u4e0a\uff0c\u4e8c\u8005\u90fd\u5bf9\u7c92\u5ea6\u8fdb\u884c\u4e86\u4e25\u683c\u7684\u63a7\u5236\uff0c<span style=\"color: rgb(8, 8, 8);font-family: Arial;font-size: 15px;text-align: justify;\">Aristada\u662f\u5178\u578b\u7684\u7eb3\u7c73\u6676\u4ea7\u54c1\uff0c\u800c<span style=\"font-size: 15px;text-align: justify;font-family: Arial;color: rgb(8, 8, 8);letter-spacing: 0.7px;\">A<\/span><span style=\"font-size: 15px;text-align: justify;font-family: Arial;color: rgb(8, 8, 8);letter-spacing: -0.1px;\">b<\/span><span style=\"font-size: 15px;letter-spacing: 0px;text-align: justify;font-family: Arial;color: rgb(8, 8, 8);\">ili<\/span><span style=\"font-size: 15px;text-align: justify;font-family: Arial;color: rgb(8, 8, 8);letter-spacing: -0.7px;\">f<\/span><span style=\"font-size: 15px;letter-spacing: 0px;text-align: justify;font-family: Arial;color: rgb(8, 8, 8);\">y&nbsp;<\/span><span style=\"font-size: 15px;text-align: justify;font-family: Arial;color: rgb(8, 8, 8);letter-spacing: -0.47px;\">M<\/span><span style=\"font-size: 15px;text-align: justify;font-family: Arial;color: rgb(8, 8, 8);letter-spacing: -0.1px;\">a<\/span><span style=\"font-size: 15px;letter-spacing: 0px;text-align: justify;font-family: Arial;color: rgb(8, 8, 8);\">i<\/span><span style=\"font-size: 15px;text-align: justify;font-family: Arial;color: rgb(8, 8, 8);letter-spacing: -0.1px;\">n<\/span><span style=\"font-size: 15px;text-align: justify;font-family: Arial;color: rgb(8, 8, 8);letter-spacing: -0.7px;\">t<\/span><span style=\"font-size: 15px;text-align: justify;font-family: Arial;color: rgb(8, 8, 8);letter-spacing: -0.1px;\">en<\/span><span style=\"font-size: 15px;letter-spacing: 0px;text-align: justify;font-family: Arial;color: rgb(8, 8, 8);\">a\u4e5f\u4f7f\u7528\u4e86\u7c7b\u4f3c\u7eb3\u7c73\u6676\u7684\u5fae\u7c89\u5316\u6280\u672f\u3002\u5e02\u573a\u65b9\u9762\uff0c<span style=\"font-size: 15px;text-align: justify;font-family: Arial;color: rgb(8, 8, 8);letter-spacing: 0.7px;\">A<\/span><span style=\"font-size: 15px;text-align: justify;font-family: Arial;color: rgb(8, 8, 8);letter-spacing: -0.1px;\">b<\/span><span style=\"font-size: 15px;letter-spacing: 0px;text-align: justify;font-family: Arial;color: rgb(8, 8, 8);\">ili<\/span><span style=\"font-size: 15px;text-align: justify;font-family: Arial;color: rgb(8, 8, 8);letter-spacing: -0.7px;\">f<\/span><span style=\"font-size: 15px;letter-spacing: 0px;text-align: justify;font-family: Arial;color: rgb(8, 8, 8);\">y&nbsp;<\/span><span style=\"font-size: 15px;text-align: justify;font-family: Arial;color: rgb(8, 8, 8);letter-spacing: -0.47px;\">M<\/span><span style=\"font-size: 15px;text-align: justify;font-family: Arial;color: rgb(8, 8, 8);letter-spacing: -0.1px;\">a<\/span><span style=\"font-size: 15px;letter-spacing: 0px;text-align: justify;font-family: Arial;color: rgb(8, 8, 8);\">i<\/span><span style=\"font-size: 15px;text-align: justify;font-family: Arial;color: rgb(8, 8, 8);letter-spacing: -0.1px;\">n<\/span><span style=\"font-size: 15px;text-align: justify;font-family: Arial;color: rgb(8, 8, 8);letter-spacing: -0.7px;\">t<\/span><span style=\"font-size: 15px;text-align: justify;font-family: Arial;color: rgb(8, 8, 8);letter-spacing: -0.1px;\">en<\/span><span style=\"font-size: 15px;letter-spacing: 0px;text-align: justify;font-family: Arial;color: rgb(8, 8, 8);\">a\u83b7\u6279\u65f6\u95f4\u76f8\u5bf9\u8f83\u65e9\uff0c2017\u5e74\uff0c\u5927\u51a2\u548c\u7075\u5317\u4e24\u5bb6\u516c\u53f8\u7684\u603b\u9500\u552e\u989d\u5df2\u7ecf\u63a5\u8fd19\u4ebf\u7f8e\u5143\uff0c\u800c<span style=\"color: rgb(8, 8, 8);font-family: Arial;font-size: 15px;text-align: justify;\">Aristada\u624d\u521a\u5f00\u59cb\u653e\u91cf\uff0c2017\u5e74\u9500\u552e\u989d\u8fbe1.4\u4ebf\u7f8e\u5143\u3002<\/span><\/span><\/span><\/span><\/span><\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 15px;\"><span style=\"font-family: Arial;color: rgb(8, 8, 8);letter-spacing: 0px;\"><span style=\"color: rgb(8, 8, 8);font-family: Arial;font-size: 15px;text-align: justify;\"><span style=\"font-size: 15px;letter-spacing: 0px;text-align: justify;font-family: Arial;color: rgb(8, 8, 8);\"><span style=\"font-size: 15px;letter-spacing: 0px;text-align: justify;font-family: Arial;color: rgb(8, 8, 8);\"><span style=\"color: rgb(8, 8, 8);font-family: Arial;font-size: 15px;text-align: justify;\"><br  \/><\/span><\/span><\/span><\/span><\/span><\/span><\/p>\n<p style=\"text-align: justify;\"><strong><span style=\"color:#080808;font-family:Arial;\"><span style=\"font-size: 15px;\">\u5170\u745e\u80bd<\/span><\/span><\/strong><span style=\"color:#080808;font-family:Arial;\"><span style=\"font-size: 15px;\">&nbsp; \u5170\u745e\u80bd\u662f\u4e00\u79cd\u5408\u6210\u751f\u957f\u6291\u7d20\u7c7b\u4f3c\u7269\uff0c\u4e3a\u4e86\u5ef6\u957f\u7ed9\u836f\u5468\u671f\uff0cIpsen\u5c06\u5176\u5236\u6210\u4e86\u534a\u56fa\u4f53\u7f13\u91ca\u5904\u65b9\u3002<\/span><\/span><span style=\"font-size: 15px;\">Somatuline Depot\u4e2d\u5e76\u4e0d\u542b\u6709\u7f13\u91ca\u6750\u6599\uff0c\u800c\u662f\u901a\u8fc7\u5fae\u5b54\u6324\u51fa\u7684\u65b9\u5f0f\u628a\u836f\u7269\u5236\u6210\u76f4\u5f84\u53ea\u67091.4\u6beb\u7c73\u7684\u201c\u7ec6\u4e1d\u201d\uff0c\u7ecf\u8fc7\u771f\u7a7a\u5e72\u71e5\u540e\uff0c\u518d\u5207\u6210\u5c0f\u9897\u7c92\u5e76\u653e\u5165\u9884\u5145\u6ce8\u5c04\u5668\u4e2d\u3002\u6ce8\u5c04\u65f6\u6df7\u5165\u5c11\u91cf\u7684\u6c34\u5f62\u6210\u6df7\u60ac\u6db2\uff0c\u836f\u7269\u8fdb\u5165\u76ae\u4e0b\u7ec4\u7ec7\u540e\u518d\u4e0e\u4f53\u6db2\u5f62\u6210\u51dd\u80f6\uff0c\u4ece\u800c\u5b9e\u73b0\u957f\u65f6\u95f4\u7684\u91ca\u653e\u3002<\/span><span style=\"font-size: 15px;\">\u672c\u54c1\u7684\u5236\u5242\u4e13\u5229\u663e\u793a\uff0c<\/span><span style=\"font-size: 15px;\">\u8fd9\u79cd\u534a\u56fa\u4f53\u7ec4\u5408\u7269<\/span><span style=\"font-size: 15px;\">\u53ef\u7ef4\u6301\u8840\u836f\u6d53\u5ea6\u957f\u8fbe15\u5929\uff0c\u4e0ePLGA\u5fae\u7403\u76f8\u6bd4\uff0c\u7a81\u91ca\u98ce\u9669\u66f4\u5c0f\uff0c\u4e14\u7ef4\u6301\u65f6\u95f4\u66f4\u957f(US5595760)\u3002\u5e02\u573a\u65b9\u9762\uff0c\u5170\u745e\u80bd\u7684\u9500\u552e\u989d\u589e\u957f\u975e\u5e38\u8fc5\u901f\uff0c2017\u5e74\u7684\u9500\u552e\u989d\u8fbe8.2\u4ebf\u7f8e\u5143\uff0c\u5df2\u7ecf\u6210\u4e3a\u5168\u7403\u6700\u7545\u9500\u7684\u751f\u957f\u6291\u7d20\u4e4b\u4e00\u3002<\/span><\/p>\n<p style=\"text-align: center;\"><br  \/><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 15px;\">\u9664\u4e86\u4ee5\u4e0a\u51e0\u4e2a\u4ea7\u54c1\uff0cFDA\u6279\u51c6\u7684\u6ce8\u5c04\u6df7\u60ac\u6db2\u8fd8\u5305\u62ec\u5965\u6c2e\u5e73\u7f13\u91ca\u6ce8\u5c04\u5242\u3001\u683c\u62c9\u53f8\u743c\u7f13\u91ca\u6ce8\u5c04\u5242\u3001<span style=\"font-size: 15px;text-align: justify;\">\u785d\u82ef\u544b\u6d77\u56e0\u94a0<\/span>\u548c\u7eb3\u7c73\u6c27\u5316\u94c1\uff0c\u5176\u4e2d\u7eb3\u7c73\u6c27\u5316\u94c1Feraheme\u548c\u5965\u6c2e\u5e73Zyprexa Relprevv\u5df2\u7ecf\u662f\u5e74\u9500\u552e\u989d\u8fc7\u4ebf\u7684\u54c1\u79cd\uff0c\u6839\u636eIMS\u6570\u636e\uff0c<span style=\"font-size: 15px;text-align: justify;\">Feraheme<\/span>\u8fd1\u4e09\u5e74\u7684\u9500\u552e\u989d\u90fd\u57281.2\u4ebf\u7f8e\u5143\u5de6\u53f3\uff0c\u800cZyprexa Relprevv\u57282017\u5e74\u7684\u9500\u552e\u989d\u4e5f\u8fbe\u52301.1\u4ebf\u7f8e\u5143\uff0cSustol\u56e0\u4e3a\u521a\u83b7\u6279\u4e0d\u4e45\uff0c\u5e02\u573a\u5c1a\u672a\u5b8c\u5168\u6253\u5f00\uff0c\u4e0d\u8fc7\u8fd9\u4e5f\u662f\u4e00\u4e2a\u5e74\u9500\u552e\u989d\u6709\u671b\u8d85\u8fc71\u4ebf\u7f8e\u5143\u7684\u54c1\u79cd\u3002\u808c\u8089\u677e\u5f1b\u836f<span style=\"font-size: 15px;text-align: justify;\">\u785d\u82ef\u544b\u6d77\u56e0\u94a0\u56e0\u7528\u836f\u9700\u6c42\u548c\u4e34\u5e8a\u4f18\u52bf\u6709\u9650\uff0c\u5e74\u9500\u552e\u989d\u4ec52000\u4e07\u7f8e\u5143\uff0c\u591a\u897f\u73af\u7d20\u7f13\u91ca\u6ce8\u5c04\u5242\u57fa\u672c\u5df2\u7ecf\u4e0d\u518d\u9500\u552e\u3002<\/span><\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 15px;\"><span style=\"font-size: 15px;text-align: justify;\"><br  \/><\/span><\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 15px;\"><span style=\"font-size: 15px;text-align: justify;\">\u4ee5\u4e0a\u4ea7\u54c1\u4f7f\u7528\u7684\u6280\u672f\u4e2d\uff0cAtrigel\u548cNanocrystal\u6700\u5177\u4ee3\u8868\u6027\uff0c\u4e5f\u662f\u6700\u503c\u5f97\u5f15\u8fdb\u6216\u4eff\u5236\u7684\u6280\u672f\uff0c\u5c24\u5176\u662f<span style=\"font-size: 15px;text-align: justify;\">Nanocrystal\uff0c\u4f7f\u7528\u8be5\u6280\u672f\u4e0a\u5e02\u7684\u4ea7\u54c1\u5e74\u9500\u552e\u989d\u9ad8\u8fbe40\u4ebf\u7f8e\u5143\uff0c\u540c\u65f6\u8be5\u6280\u672f\u8fd8\u662f\u4e00\u79cd\u5f88\u597d\u7684\u96be\u6eb6\u836f\u7269\u589e\u6eb6\u7b56\u7565\u3002<span style=\"font-size: 15px;text-align: justify;\">Nanocrystal\u7684\u7f3a\u70b9\u662f\u53ef\u80fd\u4e0d\u9002\u4e8e\u591a\u80bd\u836f\u7269\u7684\u5f00\u53d1\uff0c\u800c<span style=\"font-size: 15px;text-align: justify;\">Atrigel\u53ef\u4ee5\uff0c<\/span><\/span>\u76f8\u6bd4PLGA\u5fae\u7403\uff0c<span style=\"font-size: 15px;text-align: justify;\">Atrigel\u7684\u8f7d\u836f\u91cf\u66f4\u5927\uff0c\u6ce8\u5c04\u4f53\u79ef\u66f4\u5c0f\uff0c\u4e5f\u662f\u4e00\u79cd\u975e\u5e38\u4f18\u826f\u7684\u7f13\u91ca\u6ce8\u5c04\u5242\u8f7d\u836f\u6280\u672f\uff0c\u4f46\u7f8e\u4e2d\u4e0d\u8db3\u7684\u662f\u8be5\u6280\u672f\u4f7f\u7528\u4e86N-\u7532\u57fa\u5421\u54af\u70f7\u916e\uff0c\u8fd9\u662f\u4e00\u79cd\u6709\u6bd2\u6027\u7269\u8d28\u3002<\/span><\/span><\/span><\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"text-align: justify;\"><br  \/><\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"text-align: justify;\"><\/span><\/p>\n<section class=\"RankEditor\" style=\"margin-right: auto;margin-left: auto;border-width: 0px;border-style: none;border-color: initial;margin-top: 20px;\">\n<section style=\"width: 0.6em;display: inline-block;vertical-align: middle;\"><span style=\"width: 0.6em;height: 0.6em;display: block;opacity: 0.2;color: rgb(255, 255, 255);background-color: rgb(214, 0, 74);\"><\/span><span style=\"color: rgb(192, 0, 0);\"><span style=\"margin-top: 2px;margin-bottom: 2px;width: 0.6em;height: 0.6em;display: block;opacity: 0.6;color: rgb(255, 255, 255);background-color: rgb(214, 0, 74);\"><\/span><span style=\"width: 0.6em;height: 0.6em;display: block;opacity: 1;color: rgb(255, 255, 255);background-color: rgb(214, 0, 74);\"><\/span><\/span><\/section>\n<section style=\"padding-left: 10px;display: inline-block;vertical-align: middle;font-weight: 700;color: rgb(214, 0, 74);\">\n<section class=\"active brush\"><span style=\"color: rgb(192, 0, 0);\">\u5c0f\u7ed3<\/span><\/section>\n<\/section>\n<\/section>\n<p style=\"text-align: justify;\"><br  \/><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 15px;\">\u81ea2015\u5e747\u670822\u65e5\u4ee5\u6765\uff0c\u56fd\u5bb6\u9646\u7eed\u51fa\u53f0\u4e86\u4e00\u7cfb\u5217\u7684\u836f\u54c1\u65b0\u653f\uff0c\u4ece\u4e34\u5e8a\u81ea\u67e5\u5230\u6ce8\u518c\u5206\u7c7b\u6539\u9769\uff0c\u4ece\u4e00\u81f4\u6027\u8bc4\u4ef7\u5230\u4e0a\u5e02\u8bb8\u53ef\u4eba\u5236\u5ea6\uff0c\u4ece\u5efa\u7acb\u4e13\u5229\u94fe\u63a5\u5236\u5ea6\u5230\u516c\u5f00\u5ba1\u8bc4\u5ba1\u6279\u4fe1\u606f\uff0c\u8fd9\u4e00\u7cfb\u5217\u7684\u653f\u7b56\u4f7f\u5f97\u4eff\u5236\u836f\u5f00\u53d1\u6210\u672c\u8d8a\u6765\u8d8a\u9ad8\uff0c\u5468\u671f\u8d8a\u6765\u8d8a\u957f\uff0c\u98ce\u9669\u8d8a\u6765\u8d8a\u5927\uff0c\u800c\u4e14\u5927\u91cf\u7684\u8bc1\u636e\u8868\u660e\u5728\u672a\u6765\u7684\u51e0\u5e74\u91cc\uff0c\u4eff\u5236\u836f\u4e0d\u4f1a\u518d\u662f\u4e2d\u56fd\u836f\u54c1\u5e02\u573a\u7684\u4e3b\u8981\u589e\u957f\u70b9\u3002\u4e0d\u4f46\u5982\u6b64\uff0c\u8fd1\u5e74\u6765\u56fd\u5bb6\u4e00\u76f4\u9f13\u52b1\u521b\u65b0\uff0c\u800c\u4e14\u5f3a\u8c03\u8981\u4ece\u4e2d\u56fd\u65b0\u5230\u5168\u7403\u65b0\u3002CFDA\u52a0\u5165ICH\u3001\u627f\u8ba4\u56fd\u5916\u4e34\u5e8a\u8bd5\u9a8c\u6570\u636e\u3001\u5141\u8bb8\u5883\u5916\u673a\u6784\u5728\u4e2d\u56fd\u5f00\u5c55\u4e00\u671f\u4e34\u5e8a\u8bd5\u9a8c\uff0c\u8fd9\u4f7f\u5f97\u4e2d\u56fd\u7684\u836f\u54c1\u5e02\u573a\u4e00\u4e0b\u5b50\u8fdb\u5165\u4e16\u754c\u7684\u201c\u5927\u6d41\u201d\uff0c\u836f\u54c1\u7814\u53d1\u4e5f\u5fc5\u987b\u4e0e\u4e16\u754c\u540c\u6b65\u3002<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 15px;\"><br  \/><\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 15px;\"><span style=\"font-size: 15px;text-align: justify;\">\u9006\u6c34\u884c\u821f\uff0c\u4e0d\u8fdb\u5219\u9000\uff0c<\/span>\u57cb\u5934\u82e6\u5e72\uff0c\u95ed\u95e8\u9020\u8f66\u7684\u65e5\u5b50\u5df2\u7ecf\u4e00\u53bb\u4e0d\u590d\u8fd4\u4e86\uff0c\u56e0\u6b64\u6211\u4eec\u5fc5\u987b\u8981\u6539\u53d8\u6211\u4eec\u8fc7\u53bb\u7684\u53d1\u5c55\u6a21\u5f0f\uff0c\u5bfb\u627e\u4e00\u6761\u9002\u5408\u4e8e\u81ea\u5df1\u7684\u51fa\u6d77\u4e4b\u8def\u3002\u5bf9\u4e8e\u4e2d\u56fd\u836f\u4f01\u800c\u8a00\uff0c\u5236\u5242\u521b\u65b0\u6216\u8bb8\u662f\u4e00\u79cd\u975e\u5e38\u6709\u6548\u7684\u53d1\u5c55\u601d\u8def\u3002<\/span><span style=\"font-size: 15px;\">\u76f8\u6bd4\u65b0\u5206\u5b50\u5b9e\u4f53\uff0c\u5f00\u53d1\u521b\u65b0\u5236\u5242\u6295\u5165\u66f4\u4f4e\uff0c\u5468\u671f\u66f4\u77ed\uff0c\u98ce\u9669\u66f4\u5c0f\uff0c2017\u5e74FDA\u6279\u51c6\u7684156\u4e2a\u65b0\u836f\u4e2d2\/3\u662f505(b)2\u6b63\u597d\u8bf4\u660e\u4e86\u8fd9\u4e00\u70b9\u3002\u5c3d\u7ba1\u590d\u6742\u6ce8\u5c04\u5242\u7684\u5f00\u53d1\u96be\u5ea6\u8fdc\u5927\u4e8e\u4e00\u822c\u521b\u65b0\u5236\u5242\uff0c\u4f46\u56fd\u5185\u4e5f\u4e0d\u4e4f\u6210\u529f\u7684\u5148\u4f8b\u3002<\/span><span style=\"font-size: 15px;\">2017\u5e74\uff0c\u6ce8\u5c04\u4e73\u5242\u3001\u6ce8\u5c04\u5fae\u7403\u3001\u6ce8\u5c04\u6df7\u60ac\u6db2\u548c\u6ce8\u5c04\u8102\u8d28\u4f53\u7b49\u590d\u6742\u6ce8\u5c04\u5242\u7684\u5e02\u573a\u89c4\u6a21\u5df2\u7ecf\u8fbe\u5230180\u4ebf\u7f8e\u5143\uff0c\u800c\u4e14\u8fd8\u5728\u9ad8\u901f\u589e\u957f\u4e2d\uff0c\u5e76\u6709\u671b\u5728\u672a\u6765\u76845\u5e74\u91cc\u8fbe\u5230200\u4ebf\u7f8e\u5143\uff0c<\/span><span style=\"font-size: 15px;\">\u56e0\u6b64\u590d\u6742\u6ce8\u5c04\u5242\u53ef\u8c13\u662f\u57cb\u5728\u4e2d\u56fd\u836f\u4f01\u51fa\u6d77\u8def\u4e0a\u7684\u4e00\u5ea7\u91d1\u77ff\u3002<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 15px;\"><br  \/><\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 15px;\">\u56e0\u4e3a\u590d\u6742\u6ce8\u5c04\u5242\u4e00\u822c\u4ea7\u91cf\u4f4e\uff0c\u4ef7\u683c\u8d35\uff0c\u56e0\u6b64\u5e02\u573a\u4e3b\u8981\u96c6\u4e2d\u5728\u7f8e\u56fd\u3001\u6b27\u6d32\u548c\u65e5\u672c\uff0c\u867d\u7136\u6211\u56fd\u7684\u590d\u6742\u6ce8\u5c04\u5242\u5e02\u573a\u867d\u7136\u53d1\u5c55\u6bd4\u8f83\u5feb\uff0c\u4f46\u5728\u5168\u7403\u8303\u5e02\u573a\u5185\u5360\u6bd4\u4f9d\u7136\u5f88\u5c0f\uff0c\u5c24\u5176\u662f\u5fae\u7403\u548c\u6ce8\u5c04\u6df7\u60ac\u6db2\u3002\u56e0\u6b64\u6211\u4eec\u4e0d\u80fd\u628a\u773c\u5149\u5c40\u9650\u5728\u56fd\u5185\uff0c\u8981\u653e\u773c\u5168\u7403\u3002\u9664\u6b64\u4ee5\u5916\uff0c\u9002\u5408\u4e8e\u5f00\u53d1\u6ce8\u5c04\u5242\u7684\u4ea7\u54c1\u4e0d\u591a\uff0c\u83b7\u6279\u4e0a\u5e02\u4ea7\u54c1\u66f4\u662f\u5c11\u4e4b\u53c8\u5c11\uff0c<span style=\"font-size: 15px;text-align: justify;\">\u6210\u529f\u7684\u4ea7\u54c1\u5f80\u5f80\u662f\u53ef\u671b\u800c\u4e0d\u53ef\u6c42\uff0c\u56e0\u6b64\u6211\u4eec\u5728\u5e03\u5c40\u590d\u6742\u6ce8\u5c04\u5242\u7684\u65f6\u5019\uff0c\u4e0d\u4f46\u8981\u5b66\u4f1a\u4eff\u5236\uff0c\u800c\u4e14\u8fd8\u8981\u5b66\u4f1a\u521b\u65b0\uff0c\u5145\u5206\u53d1\u6325\u4e3b\u89c2\u80fd\u52a8\u6027\uff0c\u89c1\u7f1d\u63d2\u9488\u5730\u53bb\u5bfb\u627e\u4e34\u5e8a\u4f18\u52bf\uff0c\u730e\u53d6\u4e00\u5207\u53ef\u80fd\u7684\u5546\u673a\uff0c\u5426\u5219\u6700\u540e\u7684\u7ed3\u5c40\u53ef\u80fd\u662f\u5927\u91cf\u7684\u4eff\u5236\u836f\u5382\u5bb6\u4e00\u54c4\u800c\u4e0a\uff0c\u8d70\u5728\u524d\u9762\u7684\u53ef\u4ee5\u5403\u5230\u4e00\u70b9\u8089\uff0c\u8d70\u5728\u540e\u9762\u7684\u751a\u81f3\u559d\u4e0d\u5230\u4e00\u53e3\u6c64\uff0c\u751a\u81f3\u534a\u9014\u800c\u5e9f\uff0c\u8d54\u4e86\u592b\u4eba\u53c8\u6298\u5175\u3002<\/span><\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 15px;\"><span style=\"font-size: 15px;text-align: justify;\"><br  \/><\/span><\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 15px;\"><span style=\"font-size: 15px;text-align: justify;\">\u53c2\u8003\u6587\u732e\uff1a\u7565<\/span><\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 15px;\"><span style=\"font-size: 15px;text-align: justify;\"><br  \/><\/span><\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 15px;\"><span style=\"font-size: 15px;text-align: justify;\">\u7248\u6743\u6240\u6709\uff0c\u4e25\u7981\u79c1\u81ea\u8f6c\u8f7d\u3001\u6284\u88ad\u3001\u6539\u7f16\uff0c\u5426\u5219\u4e00\u5f8b\u89c6\u4e3a\u6076\u610f\u4fb5\u6743\uff0c\u5982\u82e5\u88ab\u4fb5\u6743\uff0c\u5fc5\u8ffd\u7a76\u6cd5\u5f8b\u8d23\u4efb\u3002<\/span><\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 15px;\"><span style=\"font-size: 15px;text-align: justify;\"><\/span><\/span><\/p>\n<section style=\"margin-top: 20px;max-width: 677px;box-sizing: border-box;word-wrap: break-word;color: rgb(51, 51, 51);text-align: justify;white-space: normal;background-color: rgb(255, 255, 255);font-family: \u5fae\u8f6f\u96c5\u9ed1;letter-spacing: 1px;line-height: 25.6px;\">\n<section style=\"max-width: 677px;box-sizing: border-box;word-wrap: break-word;\">\n<section style=\"padding-right: 10px;padding-left: 10px;max-width: 677px;box-sizing: border-box;word-wrap: break-word;background-color: rgb(208, 169, 115);display: inline-block;height: 40px;line-height: 40px;min-width: 17px;vertical-align: middle;\">\n<section style=\"max-width: 64px;box-sizing: border-box;word-wrap: break-word;color: rgb(255, 255, 255);height: 40px;min-width: 20px;font-size: 15px;\">\u5e7f\u800c\u544a\u4e4b<\/section>\n<\/section>\n<\/section>\n<section style=\"font-size: 17px;margin-top: -21px;margin-left: 30px;padding-top: 20px;padding-bottom: 20px;max-width: 677px;box-sizing: border-box;word-wrap: break-word;border-color: rgb(208, 169, 115) rgb(208, 169, 115) rgb(208, 169, 115) rgb(51, 51, 51);border-style: dashed dashed dashed none;border-width: 2px 2px 2px 0px;\">\n<section style=\"margin-left: -20px;max-width: 645px;box-sizing: border-box;word-wrap: break-word;\">\n<p style=\"max-width: 645px;box-sizing: border-box;word-wrap: break-word;min-height: 17px;color: rgb(6, 6, 6);\"><span style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word;font-size: 15px;\">\u2299&nbsp;\u540c\u5199\u610f\u57f9\u8bad<\/span><\/p>\n<p style=\"max-width: 645px;box-sizing: border-box;word-wrap: break-word;min-height: 17px;\"><a href=\"https:\/\/mp.weixin.qq.com\/s?__biz=MzI5ODI5NDE2OA==&amp;mid=2247495336&amp;idx=2&amp;sn=b31a11dcdbcd206defea813152c5993d&amp;scene=21#wechat_redirect\" target=\"_blank\" style=\"color: rgb(0, 82, 255);text-decoration: underline;-webkit-tap-highlight-color: rgba(0, 0, 0, 0);max-width: 100%;box-sizing: border-box;word-wrap: break-word;font-size: 15px;\"><span style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word;\">\u5199\u610f\u8bba\u575b\u4e28\u5c0f\u5206\u5b50\u521b\u65b0\u836f\u7269\u53d1\u73b0\uff08\u9644180\u4f4d\u53c2\u4f1a\u8005\u4fe1\u606f\uff09<\/span><\/a><br style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word;\"  \/><\/p>\n<p style=\"max-width: 645px;box-sizing: border-box;word-wrap: break-word;min-height: 17px;\"><span style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word;color: rgb(0, 82, 255);text-decoration: underline;font-size: 15px;-webkit-tap-highlight-color: rgba(0, 0, 0, 0);\"><a href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MzI5ODI5NDE2OA==&amp;mid=2247494784&amp;idx=2&amp;sn=1c457feb0fc67e66502a0215a39cb655&amp;chksm=ecaaa277dbdd2b61695b93a95135622459e3339a59521782b14c82c230d37a76a8c7763c8309&amp;scene=21#wechat_redirect\" target=\"_blank\" style=\"color: rgb(0, 82, 255);-webkit-tap-highlight-color: rgba(0, 0, 0, 0);max-width: 100%;box-sizing: border-box;word-wrap: break-word;\">\u5c0f\u5206\u5b50\u521b\u65b0\u836f\u7269\u53d1\u73b0\u2014\u2014\u7406\u8bba\u3001\u5b9e\u8df5\u3001\u8fc7\u7a0b\u4e0e\u5c55\u671b<\/a><\/span><br style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word;\"  \/><\/p>\n<p style=\"max-width: 645px;box-sizing: border-box;word-wrap: break-word;min-height: 17px;\"><span style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word;color: rgb(0, 82, 255);-webkit-tap-highlight-color: rgba(0, 0, 0, 0);text-decoration: underline;font-size: 15px;\"><a href=\"https:\/\/mp.weixin.qq.com\/s?__biz=MzI5ODI5NDE2OA==&amp;mid=2247495740&amp;idx=2&amp;sn=5730f48e350b775d76fbe0f2ddb7b11d&amp;scene=21#wechat_redirect\" target=\"_blank\" style=\"color: rgb(87, 107, 149);-webkit-tap-highlight-color: rgba(0, 0, 0, 0);max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\">\u5199\u610f\u8bba\u575b\u4e28\u65b0\u836f\u4e2d\u7f8e\u53cc\u62a5\u4e4b\u5236\u5242\u6eb6\u51fa\u6280\u672f\u5f00\u53d1<\/a><\/span><\/p>\n<p style=\"max-width: 645px;box-sizing: border-box;word-wrap: break-word;min-height: 17px;\"><span style=\"color: rgb(87, 107, 149);-webkit-tap-highlight-color: rgba(0, 0, 0, 0);max-width: 100%;box-sizing: border-box;word-wrap: break-word;font-size: 15px;text-decoration: underline;\"><a href=\"https:\/\/mp.weixin.qq.com\/s?__biz=MzI5ODI5NDE2OA==&amp;mid=2247495753&amp;idx=2&amp;sn=86f8f5bdde6849a6e35848be58f4e1c6&amp;scene=21#wechat_redirect\" target=\"_blank\" style=\"color: rgb(87, 107, 149);-webkit-tap-highlight-color: rgba(0, 0, 0, 0);max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\">\u5199\u610f\u8bba\u575b\u4e28\u56fd\u9645\u89c4\u8303\u4e0b\u751f\u7269\u836f\u5168\u751f\u547d\u5468\u671f\u8d28\u91cf\u7ba1\u7406<\/a><\/span><\/p>\n<p style=\"max-width: 645px;box-sizing: border-box;word-wrap: break-word;min-height: 17px;\"><a href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MzI5ODI5NDE2OA==&amp;mid=2247495790&amp;idx=2&amp;sn=718dd5d02dd76f06a4ef7064348a8fdb&amp;chksm=ecaabe99dbdd378f16da63761667e26cdac884284b6352d754af9b6523723de1f25563955685&amp;scene=21#wechat_redirect\" target=\"_blank\">\u5199\u610f\u516c\u76ca\u4e28\u4eff\u5236\u836f\u4e00\u81f4\u6027\u8bc4\u4ef7\u5927\u76d8\u70b9\u4e0e\u603b\u51b3\u6218<\/a><br  \/><\/p>\n<\/section>\n<section style=\"margin-left: -20px;max-width: 645px;box-sizing: border-box;word-wrap: break-word;\">\n<p style=\"max-width: 645px;box-sizing: border-box;word-wrap: break-word;min-height: 17px;\"><span style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word;font-size: 15px;\">\u2299 \u57f9\u4f18\u57f9\u8bad<\/span><\/p>\n<p style=\"max-width: 645px;box-sizing: border-box;word-wrap: break-word;min-height: 17px;\"><span style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word;color: rgb(0, 128, 255);text-decoration: underline;-webkit-tap-highlight-color: rgba(0, 0, 0, 0);font-size: 15px;\"><a href=\"https:\/\/mp.weixin.qq.com\/s?__biz=MzIyMjU0ODMxMg==&amp;mid=2247485992&amp;idx=2&amp;sn=dffcb15674c7bea6066b70387f36e740&amp;scene=21#wechat_redirect\" target=\"_blank\" style=\"color: rgb(87, 107, 149);-webkit-tap-highlight-color: rgba(0, 0, 0, 0);max-width: 100%;box-sizing: border-box;word-wrap: break-word;\">\u4f1a\u8baf|\u6539\u826f\u578b\u521b\u65b0\/505(b)(2)\u7acb\u9879\u7814\u53d1\u66a8\u4e2d\u7f8e\u53cc\u62a5\u7814\u8ba8\u4f1a\u9080\u8bf7\u51fd<\/a><\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n<p style=\"text-align: justify;\"><br  \/><\/p>\n<hr style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\"  \/>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;word-wrap: break-word !important;text-align: center;\"><img class=\"\"     style=\"color: rgb(51, 51, 51);\" width=\"auto\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/08\/beepress9-1533691023.jpg\" alt=\"\u590d\u6742\u6ce8\u5c04\u5242\u7684\u5e02\u573a\u6982\u51b5\u548c\u53d1\u5c55\u673a\u9047\" title=\"\u590d\u6742\u6ce8\u5c04\u5242\u7684\u5e02\u573a\u6982\u51b5\u548c\u53d1\u5c55\u673a\u9047\"  \/><\/p>\n<p style=\"max-width: 677px;box-sizing: border-box;word-wrap: break-word;min-height: 17px;line-height: 27.2px;letter-spacing: 0.54px;text-align: justify;\"><span style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word;font-size: 15px;\">\u836f\u4e8b\u7eb5\u6a2a\u662f\u4e00\u4e2a\u5f00\u653e\uff0c\u7531\u81ea\u613f\u8005\u7ec4\u6210\u7684\u56e2\u4f53\uff0c\u73b0\u6709\u6210\u545838\u540d\uff0c\u5206\u522b\u4e3aVoyager88\uff08\u9b4f\u5229\u519b\uff09\uff0c\u96f7\u8bfa\u5c9b\uff0c\u4e09\u5206\u8bdd\uff0cHerman\uff0c\u6885\u5e0c\uff0c\u6587\u7af9\uff0cduke\uff0cyhqqqqq\uff0c\u5360\u5c0f\u5175\uff0c\u98ce\u4e00\u6837\u7684\u5c4e\u58f3\u90ce\uff0c\u9526\u5fc3\u7ee3\u53e3\uff0cflydp511\uff0c\u5de7\u5de7\uff0c\u4e91\u6c34\u9053\u4eba\uff0c\u9621\u4e0a\u964c\u964c\uff0c\u591a\u5df4\u80fa\uff0c\u745c\u513f\uff0cKailyn\uff0cSmall fish\uff0c\u5b50\u708e\uff0c\u514b\u683c\u83ab\uff0cVicky\uff0cPandada\uff0c\u83ab\u5306\u5306\uff0cSophia \uff0c\u4f9d\u7136\u7279\u96f7\u897f\uff0c\u5076\u9635\u96e8\uff0cAimee\uff0c\u4ed6\u5c71\u4e4b\u77f3\uff0c\u5510\u5c0f\u7396\uff0c\u96f6\u4e0b274\u2103\uff0cGloria\uff0cBreathless\uff0cLuffy\uff0c\u80e1\u4e0d\u559c\uff0c&nbsp;Helen\uff0c\u843d\u843d\uff0cSUNRISE\u3002\u6b22\u8fce\u6709\u5fd7\u4e4b\u58eb\u52a0\u5165\u6211\u4eec\u56e2\u961f\u3002\u6295\u7a3f\u3001\u5408\u4f5c\u3001\u52a0\u4e13\u4e1a\u7fa4\u8bf7\u52a0\u5fae\u4fe1442015666\uff0c\u836f\u4e8b\u7eb5\u6a2a\u4e8c\u5343\u4ebaQQ\u7fa422711855\u3002<\/span><\/p>\n<blockquote class='keep-source'>\n<p>\u59cb\u53d1\u4e8e\u5fae\u4fe1\u516c\u4f17\u53f7\uff1a                         \u836f\u4e8b\u7eb5\u6a2a                      <\/p>\n<\/blockquote>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>\u590d\u6742\u6ce8\u5c04\u5242\u662f\u76f8\u5bf9\u4e00\u822c\u6ce8\u5c04\u5242\u800c\u8a00\u7684\uff0c\u672c\u6587\u6307\u7684\u590d\u6742\u6ce8\u5c04\u5242\u5305\u62ec\u8102\u8d28\u4f53\u3001\u5fae\u7403\u3001\u4e73\u5242\u548c\u7eb3\u7c73\u7c92\u7b49\uff0c\u5c3d\u7ba1\u4ea7\u54c1\u4e0d\u591a\uff0c\u4f46\u5168\u7403\u5374\u6709 [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":20144,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[2],"tags":[],"_links":{"self":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/20143"}],"collection":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/comments?post=20143"}],"version-history":[{"count":1,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/20143\/revisions"}],"predecessor-version":[{"id":20163,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/20143\/revisions\/20163"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/media\/20144"}],"wp:attachment":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/media?parent=20143"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/categories?post=20143"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/tags?post=20143"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}