{"id":2241,"date":"2018-06-25T01:00:00","date_gmt":"2018-07-27T06:35:05","guid":{"rendered":"http:\/\/www.05921.net\/index.php\/2018\/07\/27\/20%e4%b8%aa%e6%9c%80%e5%85%b7%e4%bb%b7%e5%80%bc%e6%96%b0%e8%8d%af%e9%a1%b9%e7%9b%ae-%e8%a1%80%e6%b6%b2%e7%97%85%e9%a2%86%e5%9f%9f%e5%b1%85%e9%a6%96%ef%bc%81\/"},"modified":"2018-07-27T14:35:06","modified_gmt":"2018-07-27T06:35:06","slug":"20%e4%b8%aa%e6%9c%80%e5%85%b7%e4%bb%b7%e5%80%bc%e6%96%b0%e8%8d%af%e9%a1%b9%e7%9b%ae-%e8%a1%80%e6%b6%b2%e7%97%85%e9%a2%86%e5%9f%9f%e5%b1%85%e9%a6%96%ef%bc%81","status":"publish","type":"post","link":"https:\/\/www.05921.net\/index.php\/2241\/","title":{"rendered":"20\u4e2a\u6700\u5177\u4ef7\u503c\u65b0\u836f\u9879\u76ee \u8840\u6db2\u75c5\u9886\u57df\u5c45\u9996\uff01"},"content":{"rendered":"
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Evaluate\u533b\u836f\u6700\u8fd1\u53d1\u5e03\u7684\u300a2018\u5e74EvaluatePharma\u8bc4\u4f30\u836f\u7269\u4e16\u754c\u9884\u89c8\uff0c2024\u5e74\u5c55\u671b\u300b\u4e2d\u5bf9\u672a\u6765\u836f\u54c1\u5e02\u573a\u3001\u65b0\u836f\u7814\u7a76\u5f00\u53d1\u548c\u91cd\u8981\u6cbb\u7597\u9886\u57df\uff08\u6297\u80bf\u7624\u3001\u7cd6\u5c3f\u75c5\u3001\u6297\u7c7b\u98ce\u6e7f\u6027\u5173\u8282\u708e\u3001\u75ab\u82d7\u3001\u6297\u75c5\u6bd2\u5e02\u573a\uff09\u505a\u4e86\u5206\u6790\u9884\u6d4b\uff0c\u672c\u6587\u62df\u5bf9\u8be5\u62a5\u544a\u53d9\u8ff0\u662f\u6700\u6709\u4ef7\u503c\u768420\u4e2a\uff08Top 20\uff09\u65b0\u836f\u7814\u7a76\u5f00\u53d1\u9879\u76ee\u4f5c\u7b80\u8981\u4ecb\u7ecd\u3002<\/span><\/span>
<\/p>\n<\/section>\n<\/section>\n<\/section>\n

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\u5168\u65871893\u5b57\uff0c\u7528\u65f64\u5206\u949f<\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

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\u4f5c\u8005\uff1a<\/span><\/span>\u8bb8\u5173\u715c\u3001\u674e\u654f\u534e<\/span><\/p>\n

\u8457\u540d\u7684\u884c\u4e1a\u8c03\u67e5\u673a\u6784Evaluate\u533b\u836f\u6700\u8fd1\u53d1\u5e03\u7684\u300a2018\u5e74EvaluatePharma\u8bc4\u4f30\u836f\u7269\u4e16\u754c\u9884\u89c8\uff0c2024\u5e74\u5c55\u671b\u300b\uff08World Preview 2018, Outlook to 2024\uff09\u4e2d\u5bf9\u672a\u6765\u836f\u54c1\u5e02\u573a\u3001\u65b0\u836f\u7814\u7a76\u5f00\u53d1\u548c\u91cd\u8981\u6cbb\u7597\u9886\u57df\uff08\u6297\u80bf\u7624\u3001\u7cd6\u5c3f\u75c5\u3001\u6297\u7c7b\u98ce\u6e7f\u6027\u5173\u8282\u708e\u3001\u75ab\u82d7\u3001\u6297\u75c5\u6bd2\u5e02\u573a\uff09\u505a\u4e86\u5206\u6790\u9884\u6d4b\uff0c\u672c\u6587\u62df\u5bf9\u8be5\u62a5\u544a\u53d9\u8ff0\u662f\u6700\u6709\u4ef7\u503c\u768420\u4e2a\uff08Top 20\uff09\u65b0\u836f\u7814\u7a76\u5f00\u53d1\u9879\u76ee\u4f5c\u7b80\u8981\u4ecb\u7ecd\u3002\u539f\u6587\u4e2d\u8bb8\u591a\u9879\u76ee\u4ec5\u5217\u6709\u4ee3\u53f7\uff0c\u7b14\u8005\u5c3d\u53ef\u80fd\u7eb3\u5165\u901a\u7528\u540d\uff0c\u5e76\u52a0\u6ce8\u4e86\u9002\u5e94\u75c7\uff0c\u6587\u5b57\u90e8\u5206\u4e5f\u505a\u4e86\u8865\u5145\u3002<\/span><\/p>\n

Vertex\u516c\u53f8\u7684\u4e09\u91cd\u7ec4\u5408VX-659 + Tezacaftor + Ivacaftor\u88ab\u8ba4\u4e3a\u662f\u5236\u836f\u884c\u4e1a\u6700\u6709\u4ef7\u503c\u7684\u9879\u76ee\u3002<\/span><\/p>\n

\u901a\u8fc7\u5c06ivacaftor\uff08\u4ee5\u5546\u54c1\u540dKalydeco\u9500\u552e\uff09\u548ctezacaftor\uff08\u4e0eivacaftor\u7ec4\u5408\u4ee5Symdeko\u5546\u54c1\u540d\u9500\u552e\uff09\u4e0e\u53e6\u4e00\u79cd\u65b0\u7684\u56ca\u6027\u7ea4\u7ef4\u5316\u8de8\u819c\u8c03\u8282\u5242\uff08CFTR\uff09\u6821\u6b63\u5242VX-659\u7ed3\u5408\uff0c\u5728\u56ca\u6027\u7ea4\u7ef4\u5316\u6cbb\u7597\u9886\u57df\u4e2dVertex\u516c\u53f8\u7684\u4e3b\u5bfc\u5730\u4f4d\u5c06\u5f97\u5230\u8fdb\u4e00\u6b65\u52a0\u5f3a\u3002<\/span><\/p>\n

\u963f\u5179\u6d77\u9ed8\u75c5\u65b0\u836f\u7814\u7a76\u5f00\u53d1\u5c61\u6218\u5c61\u8d25\u3002\u76ee\u524d\u5728\u5168\u7403\u8303\u56f4\u5185\u4ecd\u6709\u8d85\u8fc7100\u79cd\u65b0\u836f\u9879\u76ee\u6b63\u5728\u8fdb\u884c\u8bd5\u9a8c\u3002\u767e\u5065\u516c\u53f8\u7684Aducanumab\u6700\u5f15\u4eba\u6ce8\u76ee\u3002\u8fd130\u5e74\u6765\uff0c\u03b2\u6dc0\u7c89\u6837\u86cb\u767d\u79ef\u805a\u88ab\u8ba4\u4e3a\u662f\u5bfc\u81f4\u963f\u5179\u6d77\u9ed8\u75c7\u4e3b\u8981\u539f\u56e0\u3002\u963f\u5179\u6d77\u9ed8\u75c7\u836f\u7269\u7814\u53d1\u4e2d\uff0c\u4fbf\u662f\u4ee5\u6e05\u9664\u3001\u51cf\u5c11\u6216\u963b\u6b62\u03b2-\u6dc0\u7c89\u6837\u86cb\u767d\u7684\u6c89\u79ef\u4e3a\u76ee\u7684\u3002\u7136\u800c\uff0c\u5728\u4e0d\u65ad\u7684\u5931\u8d25\u4e2d\uff0c\u51fa\u73b0\u4e86\u4e0d\u5c11\u5bf9\u6dc0\u7c89\u6837\u86cb\u767d\u5047\u8bf4\u771f\u5b9e\u6027\u7684\u8d28\u7591\u30022015\u5e743\u6708\uff0c\u767e\u5065\u827e\u8fea\u5ba3\u5e03\u7684\u4e00\u9879\u91cd\u8981\u4e34\u5e8a\u7814\u7a76\u6210\u679c\u2014\u2014Aducanumab\u76841b\u671f\u4e34\u5e8a\u7ed3\u679c\u663e\u793a\uff0c\u5b83\u80fd\u51cf\u5c11\u524d\u9a71\u671f\u6216\u8f7b\u5fae\u963f\u5179\u6d77\u9ed8\u75c7\u60a3\u8005\u5927\u8111\u6dc0\u7c89\u6837\u86cb\u767d\u6591\uff0c\u8fd8\u53ef\u4ee5\u5ef6\u7f13\u8ba4\u77e5\u529f\u80fd\u4e0b\u964d\uff0c\u56e0\u6b64\u88ab\u5bc4\u4e88\u539a\u671b\u3002\u76ee\u524d\uff0c\u5b83\u6b63\u5904\u4e8eIII\u671f\u4e34\u5e8a\u9636\u6bb5\uff0c\u9884\u8ba12019\u5e74\u62162020\u5e74\u53ef\u5f97\u51fa\u7ed3\u679c\u3002\u4e0d\u8fc7\uff0c\u4eca\u5e741\u6708\uff0c\u8f89\u745e\u548cAxovant\u5148\u540e\u5ba3\u5e03\u4e2d\u6b62\u5b83\u4eec\u5404\u81ea\u7684\u7814\u7a76\u9879\u76ee\uff0c\u5bf9Aducanumab\u7684\u671f\u8bb8\u4e5f\u53d7\u5230\u5f71\u54cd\uff0c\u53bb\u5e74\u4f5c\u4e3a\u6700\u6709\u4ef7\u503c\u7684\u9879\u76ee\u8dcc\u843d\u81f3\u7b2c\u4e09\u3002\u5c3d\u7ba1\u5b83\u5177\u6709\u9ad8\u56de\u62a5\u7684\u6f5c\u529b\uff0c\u4f46\u8fd9\u4e2a\u9886\u57df\u98ce\u9669\u5f88\u5927\u3002<\/span><\/p>\n

\u968f\u7740\u66f4\u591a\u4e34\u5e8a\u6570\u636e\u7684\u51fa\u73b0\uff0c\u65b0\u836f\u9879\u76ee\u51c0\u73b0\u503c\uff08NPV\uff09\u7684\u9884\u671f\u53ef\u80fd\u4f1a\u6025\u5267\u53d8\u5316\u3002\u540c\u6837\u6765\u81ea\u53bb\u5e74\u7684\u540d\u5355\uff0c\u827e\u4f2f\u7ef4\u7684upadacitinib\u5728\u8fc7\u53bb\u7684\u4e00\u5e74\u4e2d\u7c7b\u98ce\u6e7f\u5173\u8282\u708eII\u671f\u548cIII\u671f\u7814\u7a76\u7684\u90fd\u663e\u793a\u9633\u6027\u7ed3\u679c\uff0c\u4ee5\u81f3\u4e8e\u5b83\u4f9d\u7136\u4fdd\u6301\u4e86\u9884\u671f\u7684\u9ad8NPV\u3002<\/span><\/p>\n

\u524d\u51e0\u5e74\u8bb8\u591a\u80bf\u7624\u5b66\u9879\u76ee\u5728\u6700\u6709\u4ef7\u503c\u7684\u7814\u7a76\u5f00\u53d1\u9879\u76ee\u5360\u636e\u4f18\u52bf\u5730\u4f4d\uff0c\u4f46\u662f\u73b0\u800c\u73b0\u5728\u5df2\u6709\u66f4\u5e7f\u6cdb\u7684\u6cbb\u7597\u9886\u57df\u9879\u76ee\u5165\u56f4\u3002<\/span><\/p>\n

\u8fd9\u90e8\u5206\u5f97\u5f52\u56e0\u4e8e\u5f3a\u751f\u516c\u53f8\u7684Erleada\uff08apalutamide\uff0c\u4eca\u5e742\u670814\u65e5\u83b7\u51c6\uff09\uff0c\u793c\u6765\u516c\u53f8\u7684Verzenio\uff08abemaciclib\uff0c2017\u5e749\u670830\u83b7\u51c6\uff09\u548c\u8bfa\u534e\u7684CAR-T\u7ec6\u80de\u6cbb\u7597\u836fKymriah\uff08tisagenlecleucel\uff0c2017\u5e748\u670831\u65e5\u83b7\u51c6\uff09\u4eca\u5e74\u90fd\u5df2\u7ecf\u6210\u4e3a\u5e02\u573a\u8425\u9500\u8d44\u4ea7\uff0c\u4f46\u8fd9\u4e5f\u6807\u5fd7\u7740\u7814\u7a76\u5f00\u53d1\u9879\u76ee\u8d44\u4ea7\u7684\u8fd1\u671f\u53d8\u5316\uff0c\u5b83\u4eec\u90fd\u4ea7\u751f\u4e86\u5b9e\u9645\u4ef7\u503c\u3002\u6839\u636eEvaluatePharma\u91c7\u7eb3\u7684\u6cbb\u7597\u7c7b\u522b\u5206\u7c7b\uff0c\u5728Top 20\u9879\u76ee\u4e2d\uff0c\u4ee5\u7f55\u89c1\u75be\u75c5\u4e3a\u4e3b\u7684\u8840\u6db2\u75c5\u6cbb\u7597\u4ee3\u8868\u4e86\u6700\u9ad8\u7684\u603bNPV\uff0c\u5177\u4f53\u9879\u76ee\u6709Biomarin\u516c\u53f8\u7684Valoococogene Roxaparvovec\u548cShire\u516c\u53f8\u7684Lanadelumab\uff0c\u9884\u8ba1\u5b83\u4eec\u5206\u522b\u4f1a\u5bf9\u8840\u53cb\u75c5A\u548c\u9057\u4f20\u6027\u8840\u7ba1\u6027\u6c34\u80bf\u5e02\u573a\u663e\u8457\u4ea7\u751f\u5f71\u54cd\uff1b\u4ee5\u53caBluebird\u751f\u7269\u5236\u836f\u7684LentiGlobin\u3001\u65b0\u57fa\u516c\u53f8\u7684Luspatercept\u3002<\/span><\/p>\n

20\u4e2a\u9879\u76ee\u4e2d\u751f\u7269\u6280\u672f\u8d85\u8fc7\u534a\u6570\uff0c\u5176\u4e2d\u96642\u30013\u30016\u5916\uff0c\u5176\u4f59\u5747\u4e3a\u65b0\u5165\u56f4\u7684\uff0c\u4ee5\u51c0\u73b0\u503c\u5927\u5c0f\u6392\u540d\u3002\u5177\u4f53\u9879\u76ee\u89c1\u4e0b\u8868\uff1a<\/span><\/p>\n

\"20\u4e2a\u6700\u5177\u4ef7\u503c\u65b0\u836f\u9879\u76ee<\/p>\n

\"20\u4e2a\u6700\u5177\u4ef7\u503c\u65b0\u836f\u9879\u76ee<\/p>\n

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\u59cb\u53d1\u4e8e\u5fae\u4fe1\u516c\u4f17\u53f7\uff1a \u533b\u836f\u5730\u7406 <\/p>\n<\/blockquote>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

Evaluate\u533b\u836f\u6700\u8fd1\u53d1\u5e03\u7684\u300a2018\u5e74EvaluatePharma\u8bc4\u4f30\u836f\u7269\u4e16\u754c\u9884\u89c8\uff0c2024\u5e74\u5c55\u671b\u300b\u4e2d\u5bf9\u672a […]<\/p>\n","protected":false},"author":1,"featured_media":2242,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[2],"tags":[],"_links":{"self":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/2241"}],"collection":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/comments?post=2241"}],"version-history":[{"count":1,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/2241\/revisions"}],"predecessor-version":[{"id":2245,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/2241\/revisions\/2245"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/media\/2242"}],"wp:attachment":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/media?parent=2241"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/categories?post=2241"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/tags?post=2241"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}