{"id":23344,"date":"2018-08-01T01:00:00","date_gmt":"2018-08-09T03:20:40","guid":{"rendered":"http:\/\/www.05921.net\/index.php\/2018\/08\/09\/%e7%9f%ad%e8%8a%82%e6%ae%b5%e6%a8%aa%e8%b4%af%e5%9e%8b%e8%84%8a%e9%ab%93%e7%82%8e%ef%bc%9a%e8%a7%86%e7%a5%9e%e7%bb%8f%e8%84%8a%e9%ab%93%e7%82%8e%e8%b0%b1%e7%b3%bb%e7%96%be%e7%97%85%ef%bc%9f%e5%a4%9a\/"},"modified":"2018-08-09T11:20:42","modified_gmt":"2018-08-09T03:20:42","slug":"%e7%9f%ad%e8%8a%82%e6%ae%b5%e6%a8%aa%e8%b4%af%e5%9e%8b%e8%84%8a%e9%ab%93%e7%82%8e%ef%bc%9a%e8%a7%86%e7%a5%9e%e7%bb%8f%e8%84%8a%e9%ab%93%e7%82%8e%e8%b0%b1%e7%b3%bb%e7%96%be%e7%97%85%ef%bc%9f%e5%a4%9a","status":"publish","type":"post","link":"https:\/\/www.05921.net\/index.php\/23344\/","title":{"rendered":"\u77ed\u8282\u6bb5\u6a2a\u8d2f\u578b\u810a\u9ad3\u708e\uff1a\u89c6\u795e\u7ecf\u810a\u9ad3\u708e\u8c31\u7cfb\u75be\u75c5\uff1f\u591a\u53d1\u6027\u786c\u5316\uff1f"},"content":{"rendered":"
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\u75c5\u4f8b\u56de\u987e<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

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<\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

\u60a3\u8005\u5973\u6027\uff0c59 \u5c81\uff0c\u4e3b\u56e0\u53cc\u4e0b\u80a2\u65e0\u529b 1 \u5929\u5165\u9662\u3002\u60a3\u8005\u4e8e 1 \u5929\u524d\u65e0\u660e\u663e\u8bf1\u56e0\u51fa\u73b0\u5de6\u4fa7\u4e0b\u80a2\u65e0\u529b\uff0c\u5f53\u65f6\u53ef\u81ea\u884c\u884c\u8d70\uff0c\u7ee7\u800c\u51fa\u73b0\u53f3\u4fa7\u80a2\u4f53\u65e0\u529b\uff0c\u4e0d\u80fd\u72ec\u7acb\u884c\u8d70\uff0c\u4e0d\u4f34\u6709\u5927\u5c0f\u4fbf\u5931\u7981\u3002<\/p>\n


<\/p>\n

\u65e2\u5f80\u53f2\uff1a\u8111\u5e72\u51fa\u8840 1 \u5e74\uff0c\u9057\u7559\u5de6\u4fa7\u80a2\u4f53\u65e0\u529b\u3001\u9ebb\u6728\uff1b\u9ad8\u8840\u538b\u3001\u7cd6\u5c3f\u75c5\u591a\u5e74\u3002<\/p>\n


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\u67e5\u4f53\uff1a\u795e\u5fd7\u6e05\u695a\u3001\u8a00\u8bed\u6d41\u5229\uff0c\u9885\u795e\u7ecf\u67e5\u4f53\u672a\u89c1\u660e\u663e\u5f02\u5e38\u3002\u4e0a\u80a2\u808c\u529b 5 \u7ea7\uff0c\u5de6\u4fa7\u4e0b\u80a2\u808c\u529b 3 \u7ea7\uff0c\u53f3\u4fa7\u4e0b\u80a2\u808c\u529b 3 \u7ea7\u3002\u5de6\u4fa7\u4e0b\u80a2\u8171\u53cd\u5c04\u51cf\u9000\uff0c\u5de6\u4fa7\u504f\u8eab\u75db\u6e29\u89c9\u51cf\u9000\uff0c\u53cc\u4fa7\u75c5\u7406\u5f81\u9634\u6027\u3002<\/p>\n


<\/p>\n

\u68c0\u67e5\uff1a\u5934\u9885\u3001\u9888\u690e\u3001\u8170\u690e MRI \u672a\u89c1\u65b0\u53d1\u75c5\u7076\uff0c\u80f8\u690e MRI \u89c1\u5f02\u5e38\u4fe1\u53f7\u5f71\u3002<\/p>\n


<\/p>\n

\"\u77ed\u8282\u6bb5\u6a2a\u8d2f\u578b\u810a\u9ad3\u708e\uff1a\u89c6\u795e\u7ecf\u810a\u9ad3\u708e\u8c31\u7cfb\u75be\u75c5\uff1f\u591a\u53d1\u6027\u786c\u5316\uff1f\"\"\u77ed\u8282\u6bb5\u6a2a\u8d2f\u578b\u810a\u9ad3\u708e\uff1a\u89c6\u795e\u7ecf\u810a\u9ad3\u708e\u8c31\u7cfb\u75be\u75c5\uff1f\u591a\u53d1\u6027\u786c\u5316\uff1f\"<\/p>\n


<\/p>\n

\u80f8\u690e MRI \u53ef\u89c1 T9-11 \u6c34\u5e73\u810a\u9ad3\u7a0d\u589e\u7c97\u4f34\u4fe1\u53f7\u5f02\u5e38\uff08\u75c5\u7076\uff1c3 \u4e2a\u690e\u4f53\uff09\u3002<\/p>\n


<\/p>\n

\"\u77ed\u8282\u6bb5\u6a2a\u8d2f\u578b\u810a\u9ad3\u708e\uff1a\u89c6\u795e\u7ecf\u810a\u9ad3\u708e\u8c31\u7cfb\u75be\u75c5\uff1f\u591a\u53d1\u6027\u786c\u5316\uff1f\"\"\u77ed\u8282\u6bb5\u6a2a\u8d2f\u578b\u810a\u9ad3\u708e\uff1a\u89c6\u795e\u7ecf\u810a\u9ad3\u708e\u8c31\u7cfb\u75be\u75c5\uff1f\u591a\u53d1\u6027\u786c\u5316\uff1f\"<\/p>\n


<\/p>\n

\u80f8\u690e\u5f3a\u5316\u53ef\u89c1 T9-11 \u5f02\u5e38\u5f3a\u5316\u5f71\u3002<\/p>\n


<\/p>\n

\u8111\u810a\u6db2\u5e38\u89c4\uff1a\u65e0\u8272\u3001\u900f\u660e\uff1b\u6f58\u6c0f\u53cd\u5e94\u8bd5\u9a8c \u5f31\u9633\u6027 (+)\uff1b\u767d\u7ec6\u80de 104\u00d710^6\/L\uff0c\u6709\u6838\u7ec6\u80de\u6570 105\u00d710^6\/L\uff0c\u7ea2\u7ec6\u80de 0\u00d710^9\/L\uff0c\u5355\u4e2a\u6838\u7ec6\u80de\u6570 100\u00d710^6\/L\uff0c\u5355\u4e2a\u6838\u7ec6\u80de\u767e\u5206\u6bd4 96.2 %\uff0c\u591a\u4e2a\u6838\u7ec6\u80de\u6570 4\u00d710^6\/L\uff0c\u591a\u4e2a\u6838\u7ec6\u80de\u767e\u5206\u6bd4 3.8 %, \u55dc\u9178\u7ec6\u80de\u6570 0\u00d710^6\/L, \u55dc\u9178\u7ec6\u80de\u767e\u5206\u6bd4 0 %\u3002<\/p>\n


<\/p>\n

\u751f\u5316\uff1a\u6c2f\uff1a128.00 mmol\/L\uff0c\u8111\u810a\u6db2\u603b\u86cb\u767d\uff1a88.05 mg\/dL\uff0c\u8111\u810a\u6db2\u7cd6\uff1a62.88 mg\/dL<\/p>\n

\u8840\u6e05 AQP-4-Ab\uff1a\u9633\u6027\uff08+\uff09<\/p>\n


<\/p>\n

\u8bca\u65ad\uff1a\u89c6\u795e\u7ecf\u810a\u9ad3\u708e\u8c31\u7cfb\u75be\u75c5<\/p>\n

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\u75c5\u4f8b\u8ba8\u8bba<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

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<\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

\u957f\u8282\u6bb5\u6a2a\u8d2f\u6027\u810a\u9ad3\u708e\uff08LETM\uff0c\u4e00\u822c\u8ba4\u4e3a \u2265 3 \u4e2a\u690e\u4f53\uff09\uff0c\u88ab\u8ba4\u4e3a\u662f\u89c6\u795e\u7ecf\u810a\u9ad3\u708e\u8c31\u7cfb\u75be\u75c5\uff08NMOSD\uff09\u7684\u5178\u578b\u8868\u73b0\uff0c\u80fd\u591f\u63d0\u793a\u4e34\u5e8a\u533b\u5e08\u8fdb\u884c AQP4 \u6297\u4f53\u68c0\u6d4b\u3002\u6709\u5c06\u8fd1 34-45% \u7684 NMOSD \u4ee5\u810a\u9ad3\u708e\u4f5c\u4e3a\u9996\u53d1\u75c7\u72b6\uff0c\u5176\u4e2d 82-91% \u60a3\u8005\u75c5\u7a0b\u4e2d\u4f1a\u7ecf\u5386 LETM\uff0c\u800c\u4e14 LETM \u6709\u8f83\u4f4e\u7684\u591a\u53d1\u6027\u786c\u5316\uff08MS\uff09\u8f6c\u5316\u98ce\u9669\u3002<\/p>\n


<\/p>\n

\u77ed\u8282\u6bb5\u6a2a\u8d2f\u6027\u810a\u9ad3\u708e\uff08STM\uff0c<3 \u4e2a\u690e\u4f53\u8282\u6bb5\uff09\uff0c\u901a\u5e38\u8ba4\u4e3a\u5176\u5728\u591a\u53d1\u6027\u786c\u5316\uff08MS\uff09\u4e2d\u66f4\u5e38\u89c1\uff0c\u4f46 NMOSD \u5728 MRI \u4e0a\u4e5f\u53ef\u8868\u73b0\u4e3a STM\uff0c\u7ed9 NMOSD \u7684\u8bca\u65ad\u5e26\u6765\u4e86\u5f88\u5927\u7684\u56f0\u96be\uff0c\u5bfc\u81f4\u6cbb\u7597\u5ef6\u8fdf\u3002<\/p>\n

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\u56fd\u5916\u6709\u7814\u7a76\u663e\u793a\uff0c\u6709 14% \u7684\u8840\u6e05 AQP-4 \u6297\u4f53\u9633\u6027\u7684 NMOSD \u60a3\u8005\uff0c\u4ee5\u77ed\u8282\u6bb5\u7684\u810a\u9ad3\u708e\u4f5c\u4e3a\u9996\u53d1\u75c7\u72b6\uff0c\u4e14 STM \u8f83 LETM \u6b8b\u75be\u7a0b\u5ea6\u8f7b\u3002<\/p>\n


<\/p>\n

\u5bf9\u5165\u7ec4\u60a3\u8005\u8fdb\u884c\u7edf\u8ba1\u5b66\u5206\u6790\u53d1\u73b0\uff0cSTM \u9996\u53d1\u4f5c\u7684\u60a3\u8005\u6709\u4ee5\u4e0b\u7279\u5f81\u65f6\uff0c\u9700\u8981\u8003\u8651 NMOSD\uff1a<\/p>\n

1. \u975e\u767d\u79cd\u4eba\uff1b<\/p>\n

2. \u6709\u5f3a\u76f4\u6027\u75c9\u631b\uff1b<\/p>\n

3. \u5b58\u5728\u81ea\u8eab\u514d\u75ab\u6027\u75be\u75c5\uff1b<\/p>\n

4. MRI \u663e\u793a\u810a\u9ad3\u4e2d\u5fc3\u75c5\u7076\u3001T1 \u4f4e\u4fe1\u53f7\uff1b<\/p>\n

5. \u5927\u8111\u65e0\u7b26\u5408 MS \u76f8\u5173\u7684\u75c5\u7076\uff1b<\/p>\n

6. \u8111\u810a\u6db2\u5be1\u514b\u9686\u5e26\u9634\u6027\u3002<\/p>\n


<\/p>\n

\u800c\u4e00\u9879\u7531\u56fd\u5185\u5b66\u8005\u8fdb\u884c\u7684\u7814\u7a76\u663e\u793a\uff1a<\/p>\n

1. STM \u4e3a\u9996\u53d1\u7684 NMOSD \u60a3\u8005\u6709\u8f83\u5c11\u7684\u8fd0\u52a8\u4ee5\u53ca\u76f4\u80a0\u3001\u8180\u80f1\u969c\u788d\uff1b<\/p>\n

2. \u5c3d\u7ba1 NMOSD \u60a3\u8005\u8868\u73b0\u4e3a STM\uff0c\u4f46\u75c5\u7076\u5e38\u5e38>2 \u4e2a\u690e\u4f53\uff0c\u800c MS \u60a3\u8005\u75c5\u7076\u5e38\u5e38<2 \u4e2a\u690e\u4f53\uff1b<\/p>\n

3. \u9996\u53d1\u4e3a STM \u7684\u60a3\u8005\u590d\u53d1\u7387\u660e\u663e\u9ad8\u4e8e LETM \u60a3\u8005\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

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\u5173\u4e8e NMOSD \u60a3\u8005 STM \u7684\u5f62\u6210\u673a\u5236\u5c1a\u4e0d\u660e\u786e\uff0c\u6709\u4eba\u8ba4\u4e3a\u8fd9\u548c\u8fdb\u884c MRI \u7684\u65f6\u673a\u76f8\u5173\uff0c\u53ef\u80fd\u662f\u505a MRI \u7684\u65f6\u95f4\u592a\u65e9\uff0c\u75c5\u7076\u8fd8\u672a\u5b8c\u5168\u663e\u793a\u3002\u6216\u8005\u592a\u665a\uff0c\u5bfc\u81f4\u75c5\u7076\u4e0d\u8fde\u7eed\u3001\u77ed\u75c5\u7076\u6216\u8005\u65e0\u75c5\u7076\u3002<\/span>
<\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n


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\u4f46\u6709\u7814\u7a76\u663e\u793a\u4ece\u6709\u75c7\u72b6\u5230\u884c MRI \u68c0\u67e5\uff0cSTM \u60a3\u8005\u548c LETM \u60a3\u8005\u4e24\u7ec4\u4e4b\u95f4\u65e0\u7edf\u8ba1\u5b66\u5dee\u5f02\uff0c\u63d0\u793a NMOSD \u60a3\u8005 STM \u7684\u5f62\u6210\u53ef\u80fd\u548c\u65f6\u95f4\u6ca1\u6709\u5fc5\u7136\u7684\u5173\u7cfb\u3002<\/p>\n

\u8fd8\u6709\u4eba\u8ba4\u4e3a STM \u7684\u5f62\u6210\u662f\u56e0\u4e3a\u5e94\u7528\u4e86\u514d\u75ab\u6291\u5236\u5242\uff0c\u4f46\u6709\u8bb8\u591a\u4ee5 STM \u8d77\u75c5\u7684 NMOSD \u60a3\u8005\u75c5\u524d\u5e76\u672a\u5e94\u7528\u514d\u75ab\u6291\u5236\u5242\u3002<\/p>\n


<\/p>\n

STM \u5728 NMOSD \u60a3\u8005\u4e2d\u5e76\u4e0d\u5e38\u89c1\uff0c\u4f46\u662f\u5e38\u5e38\u5bfc\u81f4\u8bef\u8bca\u3001\u5ef6\u8bef\u8bca\u65ad\u3002\u4e34\u5e8a\u4e2d\u9047\u5230\u77ed\u8282\u6bb5\u6a2a\u8d2f\u578b\u810a\u9ad3\u708e\u4e5f\u5e94\u8be5\u60f3\u5230 NMOSD \u7684\u53ef\u80fd\u6027\u3002<\/p>\n


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\u63a8\u8350\u9605\u8bfb\uff1a<\/strong><\/p>\n


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Babinski \u5f81\u5929\u5929\u505a \u8fd9 8 \u4e2a\u77e5\u8bc6\u70b9\u4f60\u4e0d\u53ef\u4e0d\u77e5<\/a>
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\u6253\u7834\u5e38\u8bc6\uff01\u75c5\u7076\u4e0e\u75c7\u72b6\u540c\u4fa7\u7684\u8111\u6897\u6b7b<\/a>
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\u4e01\u9999\u56ed\u62db\u4eba\uff0c300 \u591a\u4e2a\u804c\u4f4d\u4e0d\u7528\u4e0a\u591c\u73ed\uff0c\u7ea6\u4e48\uff1f<\/a>
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\u4f5c\u8005 | \u4e01\u9999\u56ed\u795e\u7ecf\u7248\u7248\u4e3b \u67f3\u67f3\u5200<\/span><\/p>\n

\u7f16\u8f91 | \u738b\u5f18<\/span><\/p>\n

\u6295\u7a3f\u53ca\u5408\u4f5c | wanghong.dxy.cn<\/span><\/p>\n

\u9898\u56fe\u6765\u6e90 | shutterstock.com<\/span><\/p>\n

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\"\u77ed\u8282\u6bb5\u6a2a\u8d2f\u578b\u810a\u9ad3\u708e\uff1a\u89c6\u795e\u7ecf\u810a\u9ad3\u708e\u8c31\u7cfb\u75be\u75c5\uff1f\u591a\u53d1\u6027\u786c\u5316\uff1f\"<\/p>\n


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\u53c2\u8003\u6587\u732e\uff1a<\/span><\/strong><\/p>\n

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1. Flanagan EP, Weinshenker BG, Krecke KN, et al. Short myelitis lesions in aquaporin-4-IgG-positive neuromyelitis optica spectrum disorders. JAMA Neurol. 2015; 72(1):81-7.<\/span><\/p>\n


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2. Huh SY, Kim SH, Hyun JW, et al. Short segment myelitis as a first manifestation of neuromyelitis optica spectrum disorders. Mult Scler. 2017; 23(3):413-419.<\/span><\/p>\n


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3. Hu H, You X, Ye J. Short transverse myelitis in Chinese patients with neuromyelitis optica spectrum disorders. Mult Scler Relat Disord. 2018; 21:78-83.<\/span><\/p>\n


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4. Carnero Contentti E, Daccach Marques V, Soto de Castillo I, Short-segment transverse myelitis lesions in a cohort of Latin American patients with neuromyelitis optica spectrum disorders. Spinal Cord. 2018 May 22.<\/span><\/p>\n


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5. Zabad RK, Stewart R, Healey KM. Pattern Recognition of the Multiple Sclerosis Syndrome. Brain Sci. 2017 Oct 24;7(10).<\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

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