{"id":25093,"date":"2018-08-06T01:00:00","date_gmt":"2018-08-09T03:33:06","guid":{"rendered":"http:\/\/www.05921.net\/index.php\/2018\/08\/09\/%e5%81%8f%e5%a4%b4%e7%97%9b%e6%b2%bb%e7%96%97%e8%8d%af%e7%89%a9-aimoving%e5%86%8d%e8%8e%b7%e6%ac%a7%e7%9b%9f%e6%89%b9%e5%87%86\/"},"modified":"2018-08-09T11:33:08","modified_gmt":"2018-08-09T03:33:08","slug":"%e5%81%8f%e5%a4%b4%e7%97%9b%e6%b2%bb%e7%96%97%e8%8d%af%e7%89%a9-aimoving%e5%86%8d%e8%8e%b7%e6%ac%a7%e7%9b%9f%e6%89%b9%e5%87%86","status":"publish","type":"post","link":"https:\/\/www.05921.net\/index.php\/25093\/","title":{"rendered":"\u504f\u5934\u75db\u6cbb\u7597\u836f\u7269-Aimoving\u518d\u83b7\u6b27\u76df\u6279\u51c6"},"content":{"rendered":"
\n

\u70b9\u51fb\u4e0a\u65b9\u7684 \u884c\u821fDrug \u25b2 \u6dfb\u52a0\u5173\u6ce8<\/span><\/p>\n


<\/p>\n

\"\u504f\u5934\u75db\u6cbb\u7597\u836f\u7269-Aimoving\u518d\u83b7\u6b27\u76df\u6279\u51c6\"<\/p>\n


<\/p>\n

\u8fd1\u65e5\uff0c\u745e\u58eb\u5236\u836f\u5de8\u5934\u8bfa\u534e\uff08Novartis\uff09\u5ba3\u5e03\uff0c\u504f\u5934\u75db\u836f\u7269Aimovig\uff08erenumab\uff09\u5df2\u83b7\u6b27\u76df\u59d4\u5458\u4f1a\uff08EC\uff09\u6279\u51c6\uff0c\u7528\u4e8e\u6bcf\u6708\u81f3\u5c11\u7ecf\u53864\u5929\u504f\u5934\u75db\u7684\u6210\u4eba\u60a3\u8005\uff0c\u9884\u9632\u504f\u5934\u75db\u3002\u503c\u5f97\u4e00\u63d0\u7684\u662f\uff0cAimovig\u4e8e\u4eca\u5e745\u6708\u4e2d\u65ec\u83b7\u5f97\u7f8e\u56fdFDA\u6279\u51c6\uff0c\u6210\u4e3a\u5168\u7403\u9996\u4e2a\u9776\u5411CGRP\u53d7\u4f53\u7684\u504f\u5934\u75db\u836f\u7269\uff0c\u540c\u65f6\u4e5f\u662f\u7f8e\u56fd\u5e02\u573a\u8fd120\u5e74\u6765\u9996\u4e2a\u9884\u9632\u504f\u5934\u75db\u7684\u65b0\u836f\u3002FDA\u6279\u51c6\u662f\u5168\u7403\u9996\u4e2a\u4e5f\u662f\u552f\u4e00\u9884\u9632\u6027\u504f\u5934\u75db\u6cbb\u7597\u836f\u7269\u3002\u622a\u81f3\u76ee\u524d\uff0cAimovig\u5df2\u83b7\u7f8e\u56fd\u3001\u745e\u58eb\u3001\u6fb3\u5927\u5229\u4e9a\u3001\u6b27\u76df\u6279\u51c6\uff0c\u6210\u4e3a\u5168\u7403\u9996\u4e2a\u4e5f\u662f\u552f\u4e00\u4e00\u4e2a\u83b7\u6279\u4e13\u95e8\u7528\u4e8e\u9884\u9632\u504f\u5934\u75db\u7684\u836f\u7269\u3002\u7528\u836f\u65b9\u9762\uff0c\u7528\u836f\u65b9\u5f0f\u4e3a\u901a\u8fc7SureClick\u81ea\u52a8\u6ce8\u5c04\u7b14\u6bcf4\u5468\u4e00\u6b21\u76ae\u4e0b\u6ce8\u5c04\u3002<\/span><\/p>\n

 <\/span><\/p>\n

\u504f\u5934\u75db\u662f\u4e00\u79cd\u5e38\u89c1\u7684\u6162\u6027\u795e\u7ecf\u8840\u7ba1\u6027\u75be\u75c5\uff0c\u7279\u5f81\u4e3a\u53cd\u590d\u53d1\u4f5c\u7684\u5267\u70c8\u5934\u75db\uff0c\u591a\u4e3a\u504f\u4fa7\u3002\u4e16\u754c\u536b\u751f\u7ec4\u7ec7\uff08WHO\uff09\u5df2\u5c06\u504f\u5934\u75db\u6307\u5b9a\u4e3a20\u4e2a\u6700\u81f4\u6b8b\u7684\u75be\u75c5\u4e4b\u4e00\u3002\u5728\u7f8e\u56fd\uff0c\u7ea6\u67091000\u4e07\u504f\u5934\u75bc\u60a3\u8005\u7684\u65e5\u5e38\u751f\u6d3b\u56e0\u4e3a\u8be5\u75be\u75c5\u800c\u53d7\u5230\u4e25\u91cd\u56f0\u6270\u3002\u9891\u7e41\u53d1\u751f\u504f\u5934\u75db\u7684\u4eba\u53ef\u80fd\u4f1a\u56e0\u4e3a\u504f\u5934\u75db\u800c\u5931\u53bb\u4e00\u534a\u4ee5\u4e0a\u7684\u751f\u6d3b\u3002\u504f\u5934\u75db\u63a0\u593a\u4e86\u4ed6\u4eec\u4e0e\u5bb6\u4eba\u76f8\u5904\u7684\u65f6\u95f4\uff0c\u5f71\u54cd\u4e86\u5de5\u4f5c\u6548\u7387\uff0c\u4ee5\u53ca\u5176\u5b83\u4e0e\u751f\u6d3b\u76f8\u5173\u7684\u65b9\u9762\u3002\u4ed6\u4eec\u65f6\u5e38\u9700\u8981\u5fcd\u53d7\u8870\u5f31\u6027\u7684\u75bc\u75db\u3001\u8eab\u4f53\u7684\u53d7\u635f\uff0c\u5e76\u65f6\u523b\u5904\u4e8e\u5bf9\u4e0b\u4e00\u6b21\u504f\u5934\u75bc\u6765\u88ad\u7684\u6050\u60e7\u4e2d\u3002\u5bf9\u4e8e\u8fd9\u4e9b\u4eba\u6765\u8bf4\uff0c\u9884\u9632\u6027\u836f\u7269\u662f\u6cbb\u7597\u9009\u62e9\u4e4b\u4e00\u3002\u4ed6\u4eec\u4e2d\u7ea6\u6709350\u4e07\u4eba\u76ee\u524d\u6b63\u5728\u63a5\u53d7\u9884\u9632\u6027\u6cbb\u7597\uff0c\u4f46\u6709\u9ad8\u8fbe80%\u7684\u4eba\u4f1a\u56e0\u4e3a\u5404\u79cd\u539f\u56e0\u800c\u5728\u4e00\u5e74\u5185\u505c\u6b62\u7528\u836f\u3002\u8fd9\u4e9b\u60a3\u8005\u6025\u9700\u4e00\u6b3e\u66f4\u52a0\u6709\u6548\u4e14\u526f\u4f5c\u7528\u8f83\u5c0f\u7684\u836f\u7269\u6765\u7f13\u89e3\u75c5\u75db\u3002<\/span><\/p>\n


<\/p>\n

\"\u504f\u5934\u75db\u6cbb\u7597\u836f\u7269-Aimoving\u518d\u83b7\u6b27\u76df\u6279\u51c6\"<\/p>\n


<\/span><\/p>\n

\u800c\u672c\u6b21Aimovig\u7684\u83b7\u6279\u662f\u57fa\u4e8e\u5176\u5f3a\u5927\u7684\u4e34\u5e8a\u8bd5\u9a8c\u6570\u636e\uff1a\uff081\uff09\u9884\u9632\u53d1\u4f5c\u6027\u504f\u5934\u75db\uff08EM\uff0c\u6bcf\u6708\u504f\u5934\u75db\u5929\u65704-14\u5929\uff09\uff0c\u4e0e\u5b89\u6170\u5242\u7ec4\u76f8\u6bd4\uff0cAimovig\u6cbb\u7597\u7ec4\u6709\u4e00\u534a\u7684\u60a3\u8005\u6bcf\u6708\u504f\u5934\u75db\u5929\u6570\u51cf\u5c11\u4e00\u534a\u6216\u66f4\u591a\uff08STRIVE\u7814\u7a76\uff1aAimovig70mg\u548c140mg\u5242\u91cf\u5206\u522b\u4e3a43.3%\u548c50%\uff0c\u5b89\u6170\u5242\u4e3a26.6%\uff1bp\uff1c0.001\uff09\uff1b\uff082\uff09\u9884\u9632\u6162\u6027\u504f\u5934\u75db\uff08CM\uff0c\u6bcf\u670815\u5929\u6216\u66f4\u591a\u504f\u5934\u75db\u5929\u6570\uff09\uff0c\u4e0e\u5b89\u6170\u5242\u7ec4\u76f8\u6bd4\uff0cAimovig\u6cbb\u7597\u7ec4\u53d6\u5f97\u4e86\u76f8\u4f3c\u7684\u7edf\u8ba1\u5b66\u663e\u8457\u53cd\u5e94\uff08Aimovi\uff08STRIVE\u7814\u7a76\uff1aAimovig 70mg\u548c140mg\u5242\u91cf\u5206\u522b\u4e3a40%\u548c41%\uff0c\u5b89\u6170\u5242\u4e3a23%\uff0cp\uff1c0.001\uff09\u3002<\/span><\/p>\n

 <\/span><\/p>\n

Aimovig\u662f\u7531Amgen\/Novartis\u5171\u540c\u7814\u53d1\u7684\u901a\u8fc7\u9776\u5411\u963b\u65ad\u964d\u9499\u7d20\u57fa\u56e0\u76f8\u5173\u80bd\uff08CGRP\uff09\u53d7\u4f53\u7684\u9884\u9632\u504f\u5934\u75db\u7684\u836f\u7269\u3002\u800cCGRP\u5df2\u88ab\u8bc1\u660e\u5728\u504f\u5934\u75db\u53d1\u4f5c\u65f6\u91ca\u653e\uff0c\u88ab\u8ba4\u4e3a\u662f\u504f\u5934\u75db\u53d1\u4f5c\u7684\u8bf1\u56e0\uff0c\u5728\u504f\u5934\u75db\u7684\u53d1\u751f\u4e2d\u53d1\u6325\u4e86\u5173\u952e\u4f5c\u7528\u3002FDA\u836f\u7269\u8bc4\u4f30\u548c\u7814\u7a76\u4e2d\u5fc3\u795e\u7ecf\u75c5\u5b66\u4ea7\u54c1\u90e8\u526f\u4e3b\u4efbEric Bastings\u535a\u58eb\u8bf4\uff1a\u201cAimovig\u4e3a\u60a3\u8005\u63d0\u4f9b\u4e86\u4e00\u79cd\u51cf\u5c11\u504f\u5934\u75db\u5929\u6570\u7684\u65b0\u65b9\u6cd5\u3002\u6211\u4eec\u9700\u8981\u65b0\u7684\u6cbb\u7597\u65b9\u6cd5\u6765\u6cbb\u7597\u8fd9\u79cd\u4ee4\u4eba\u75db\u82e6\u5e76\u4e14\u7ecf\u5e38\u865a\u5f31\u7684\u75be\u75c5\u3002\u201d <\/span><\/p>\n

 <\/span><\/p>\n

Aimovig\u83b7\u6279\u4e0a\u5e02\u4f7f\u5176\u6210\u4e3aCGRP\u6291\u5236\u5242\u5e02\u573a\u7684\u9886\u5934\u7f8a\uff0c\u5b89\u8fdb\u548c\u8bfa\u534e\u5c06\u5728\u7f8e\u56fd\u5e02\u573a\u5171\u540c\u8425\u9500\u8be5\u836f\uff0c\u5b89\u8fdb\u62e5\u6709\u5176\u5728\u65e5\u672c\u7684\u72ec\u5bb6\u5546\u4e1a\u5316\u6743\u5229\uff0c\u8bfa\u534e\u5219\u62e5\u6709\u5728\u5168\u7403\u5176\u4ed6\u5730\u533a\u7684\u72ec\u5bb6\u5546\u4e1a\u5316\u6743\u5229\u3002\u6839\u636eEvaluatePharma\u7684\u9884\u6d4b\uff0c2018\u5e74Aimovig\u7684\u9500\u552e\u989d\u4e3a1.26\u4ebf\u7f8e\u5143\uff0c\u57282024\u5e74\u5176\u9500\u552e\u989d\u4f1a\u9ad8\u8fbe18.82\u4ebf\u7f8e\u5143\u3002<\/span><\/p>\n


<\/p>\n

\u58f0\u660e\uff1a\u8f6c\u8f7d\u8bf7\u52a1\u5fc5\u6ce8\u660e\u672c\u6587\u6765\u6e90\u53ca\u4f5c\u8005\u3002<\/strong><\/p>\n

\n
\n
\n
\n
\n
\u4f5c\u8005\u6587\u7ae0\u63a8\u8350\uff1a<\/span><\/section>\n

<\/section>\n<\/section>\n
\n
<\/section>\n<\/section>\n
\n
\n

FDA\u6279\u51c6\u56db\u5408\u4e00HIV\u65b0\u836fSymtuza<\/span><\/a><\/h2>\n

FDA\u6279\u51c6\u767d\u8840\u75c5\u65b0\u7597\u6cd5<\/span><\/a><\/h2>\n

Keytruda\u5de9\u56fa\u80ba\u764c\u4f18\u52bf\u518d\u4e0b\u4e00\u57ce<\/span><\/a><\/p>\n

\u91cd\u78c5\uff01FDA\u6279\u51c6\u9996\u4e2a\u504f\u5934\u75db\u9884\u9632\u65b0\u836f-Aimovig<\/a><\/span><\/h2>\n

\u5965\u5e0c\u66ff\u5c3c\u83b7FDA\u6279\u51c6\u7528\u4e8e\u4e00\u7ebf\u6cbb\u7597EGFR\u7a81\u53d8\u975e\u5c0f\u7ec6\u80de\u80ba\u764c<\/a><\/span><\/h2>\n

Abbvie\u7c7b\u98ce\u6e7f\u6027\u5173\u8282\u708e\u65b0\u836fUpadacitinib\u62b53\u671f\u4e34\u5e8a\u7ec8\u70b9<\/a><\/span><\/h2>\n

\u6052\u745e\u533b\u836fCDK4\/6\u6291\u5236\u5242\u8fdb\u5165II\u671f\u4e34\u5e8a<\/a><\/span><\/h2>\n

\u5f53Keytruda\u9047\u4e0aLenvatinib<\/a><\/span><\/h2>\n

\u4e5f\u8c08\u524d\u5217\u817a\u764c\u91cd\u78c5\u836f\u7269\u2014\u2014apalutamide<\/a><\/span><\/h2>\n

\u8d1d\u8fbe\u836f\u4e1aCDK4\/6\u6291\u5236\u5242\u4e34\u5e8a\u8bd5\u9a8c\u7533\u8bf7\u83b7FDA\u53d7\u7406<\/a><\/span><\/h2>\n

\u8c01\u80fd\u6253\u7834Theranos\u9b54\u5492<\/a><\/span><\/h2>\n

\u5c55\u671b2018\uff0c\u751f\u7269\u533b\u836f\u516c\u53f8\u8868\u73b0\u53ef\u671f<\/span><\/a><\/h2>\n

\u5f53\u836f\u7269\u7814\u53d1\u9047\u4e0aAI<\/a><\/span><\/h2>\n

\u91cd\u78c5!!!\u7f8e\u56fd\u9996\u4e2a\u667a\u80fd\u836f\u4e38\u83b7\u6279<\/a><\/span><\/h2>\n

\u793c\u6765\u8054\u624b\u5fb7\u5eb7\u533b\u7597\u6253\u9020\u7cd6\u5c3f\u75c5\u6570\u5b57\u5065\u5eb7\u4ea7\u54c1<\/a><\/span><\/h2>\n

\u91cd\u78c5\uff01PD-1\u795e\u836fNivolumab\u6709\u671b\u8fd1\u671f\u8fdb\u5165\u4e2d\u56fd\u5e02\u573a<\/a><\/span><\/h2>\n<\/section>\n<\/section>\n
\n
<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n
\n
\n
\n
\n
\n
\n
\n
\n
\n
\n

<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n
\n
\n
\n
\n
\n
\n
\n
\n
\n
\n
<\/section>\n<\/section>\n<\/section>\n<\/section>\n
\n
\n
\n
<\/section>\n<\/section>\n<\/section>\n<\/section>\n
\n
\n
\n
<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n
\n
\n

\u5b66\u5982\u9006\u6c34\u884c\u821f\uff0c\u4e0d\u8fdb\u5219\u9000\uff1b<\/span><\/p>\n

\u5fc3\u4f3c\u5e73\u539f\u8d70\u9a6c\uff0c\u6613\u653e\u96be\u6536\u3002<\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n

\n
\n
\n
\n
\n
<\/section>\n<\/section>\n<\/section>\n<\/section>\n
\n
\n
<\/section>\n<\/section>\n<\/section>\n
\n
\n
\n

<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n


<\/p>\n

\n


<\/p>\n


<\/p>\n

\n
\n
\n
\n
\n

\u884c\u821fDrug<\/span><\/p>\n<\/section>\n

\n

\u6bcf\u65e5\u66f4\u65b0 \u6b22\u8fce\u8ba2\u9605+<\/span><\/p>\n

\n


<\/p>\n

\"\u504f\u5934\u75db\u6cbb\u7597\u836f\u7269-Aimoving\u518d\u83b7\u6b27\u76df\u6279\u51c6\"<\/p>\n<\/section>\n


<\/p>\n

\u533b\u836f\u5927\u6570\u636e|\u884c\u4e1a\u52a8\u6001|\u653f\u7b56\u89e3\u8bfb<\/span><\/p>\n


<\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

\n

\u59cb\u53d1\u4e8e\u5fae\u4fe1\u516c\u4f17\u53f7\uff1a \u884c\u821fDrug <\/p>\n<\/blockquote>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

\u70b9\u51fb\u4e0a\u65b9\u7684 \u884c\u821fDrug \u25b2 \u6dfb\u52a0\u5173\u6ce8 \u8fd1\u65e5\uff0c\u745e\u58eb\u5236\u836f\u5de8\u5934\u8bfa\u534e\uff08Novartis […]<\/p>\n","protected":false},"author":1,"featured_media":25094,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[2],"tags":[],"_links":{"self":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/25093"}],"collection":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/comments?post=25093"}],"version-history":[{"count":1,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/25093\/revisions"}],"predecessor-version":[{"id":25102,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/25093\/revisions\/25102"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/media\/25094"}],"wp:attachment":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/media?parent=25093"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/categories?post=25093"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/tags?post=25093"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}