{"id":25940,"date":"2018-07-31T01:00:00","date_gmt":"2018-08-09T03:39:49","guid":{"rendered":"http:\/\/www.05921.net\/index.php\/2018\/08\/09\/%e7%ac%ac%e4%b8%80%e4%b8%89%e5%85%b1%e4%b8%8eglycotope%e8%81%94%e5%90%88%e5%bc%80%e5%8f%91gatipotuzumab%e7%9a%84%e6%8a%97%e4%bd%93%e5%81%b6%e8%81%94%e8%8d%af%e7%89%a9\/"},"modified":"2018-08-09T11:39:51","modified_gmt":"2018-08-09T03:39:51","slug":"%e7%ac%ac%e4%b8%80%e4%b8%89%e5%85%b1%e4%b8%8eglycotope%e8%81%94%e5%90%88%e5%bc%80%e5%8f%91gatipotuzumab%e7%9a%84%e6%8a%97%e4%bd%93%e5%81%b6%e8%81%94%e8%8d%af%e7%89%a9","status":"publish","type":"post","link":"https:\/\/www.05921.net\/index.php\/25940\/","title":{"rendered":"\u7b2c\u4e00\u4e09\u5171\u4e0eGlycotope\u8054\u5408\u5f00\u53d1gatipotuzumab\u7684\u6297\u4f53\u5076\u8054\u836f\u7269"},"content":{"rendered":"
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\"\u7b2c\u4e00\u4e09\u5171\u4e0eGlycotope\u8054\u5408\u5f00\u53d1gatipotuzumab\u7684\u6297\u4f53\u5076\u8054\u836f\u7269\"<\/p>\n

2018\u5e747\u670830\u65e5\uff0c\u7b2c\u4e00\u4e09\u5171\u682a\u5f0f\u4f1a\u793e\uff08Daiichi Sankyo\uff09\u548cGlycotope GmbH\uff08\u4ee5\u4e0b\u7b80\u79f0Glycotope\uff09\u7b7e\u8ba2\u4e86\u5168\u7403\u72ec\u5bb6\u5408\u4f5c\u534f\u8bae\uff0c\u901a\u8fc7\u628aDaiichi Sankyo\u7684\u4e13\u6709\u7684\u6297\u4f53\u836f\u7269\u5076\u8054\u6280\u672f\u4e0eGlycotope\u7684\u9776\u5411\u80bf\u7624\u76f8\u5173MUC1\u9776\u70b9\u7684\u6297\u4f53gatipotuzumab\uff08\u4ee5\u524d\u79f0\u4e3aPankoMab-GEX\u00ae\uff09\u76f8\u7ed3\u5408\u6765\u5f00\u53d1\u6297\u4f53\u5076\u8054\u836f\u7269\uff08ADC\uff09\u3002<\/p>\n


<\/p>\n

\u6839\u636e\u8bb8\u53ef\u534f\u8bae\u7684\u89c4\u5b9a\uff0c<\/span>Daiichi Sankyo\u62e5\u6709\u5168\u7403\u72ec\u5bb6\u5f00\u53d1\u548c\u9500\u552e\u6297\u4f53\u5076\u8054\u836f\u7269gatipotuzumab\u7684\u6743\u5229\u3002<\/span> Glycotope\u5c06\u83b7\u5f97\u8d39\u7528\u5305\u62ec\u9996\u4ed8\u6b3e\u3001\u4e34\u5e8a\u3001\u76d1\u7ba1\u548c\u9500\u552e\u7684\u91cc\u7a0b\u7891\u4ed8\u6b3e\uff0c\u4ee5\u53caDaiichi Sankyo\u5728\u5168\u7403\u7684\u51c0\u9500\u552e\u989d\u63d0\u6210\uff0c\u5177\u4f53\u8d22\u52a1\u6761\u6b3e\u5c1a\u672a\u62ab\u9732\u3002<\/span><\/p>\n


<\/p>\n

PankoMab-GEX\u00ae \u662fGlycotope\u5229\u7528\u5176\u4e13\u6709\u7684\u6297\u539f\u8868\u4f4d\u7cd6\u57fa\u5316\u548c\u7cd6\u57fa\u4f18\u5316\u6280\u672f\u7814\u53d1\u7684\u9776\u5411MUC1\u7684\u4eba\u6e90\u5316\u5355\u514b\u9686\u6297\u4f53\u3002<\/span>\u6297\u4f53\u5076\u8054\u836f\u7269\uff08Antibody Drug Conjugates\uff0cADC\uff09\u662f\u4e00\u7c7b\u521b\u65b0\u578b\u751f\u7269\u5236\u836f\uff0c\u7531\u5355\u514b\u9686\u6297\u4f53\u548c\u5f3a\u6548\u6bd2\u6027\u836f\u7269\uff08toxin\uff09\u901a\u8fc7\u8fde\u63a5\u4f53\uff08linker\uff09\u5076\u8054\u800c\u6210\u3002<\/span>\u6297\u4f53\u5076\u8054\u836f\u7269\uff08ADC\uff09\u501f\u52a9\u6297\u4f53\u836f\u7269\u9776\u5411\u6027\u5f3a\u7684\u7279\u70b9\uff0c\u4f7f\u7ec6\u80de\u6bd2\u836f\u7269\u76f4\u63a5\u4f5c\u7528\u4e8e\u80bf\u7624\u7ec6\u80de\uff0c\u5145\u5206\u53d1\u6325\u4e24\u79cd\u836f\u7269\u7684\u6297\u80bf\u7624\u4f18\u52bf\u3002<\/span><\/p>\n


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ADC\u793a\u610f\u56fe<\/strong><\/span><\/p>\n

       <\/p>\n

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<\/p>\n

2017\u5e74\uff0cGlycotope\u5728ESMO\u5927\u4f1a\u4e0a\u516c\u5e03\u4e86PankoMab-GEX\u5355\u4e00\u7597\u6cd5\u76842b\u671f\u4e34\u5e8a\u8bd5\u9a8c\u5931\u5229\u7684\u6d88\u606f\uff0c\u4f46Glycotope\u4ecd\u5728\u5bfb\u6c42\u6f5c\u5728\u7684\u7ec4\u5408\u7597\u6cd5\u7684\u53d1\u5c55\u673a\u4f1a\u3002<\/span>Glycotope\u4e0eDaiichi Sankyo\u5408\u4f5c\u5f00\u53d1\u6210\u6297\u4f53\u5076\u8054\u836f\u7269\uff0c\u5c06\u7a81\u51fagatipotuzumab \u7684\u6f5c\u529b\u548c\u5e7f\u6cdb\u9002\u7528\u6027\u3002 <\/span>\u8fdb\u800c\u521b\u9020\u51fa\u4e00\u79cd\u5177\u6709\u78b3\u6c34\u5316\u5408\u7269\u4ecb\u5bfc\u7684\u80bf\u7624\u7279\u5f02\u6027\u548c\u9ad8\u4eb2\u548c\u529b\u7ed3\u5408\u7684\u65b0\u578b\u6297\u80bf\u7624\u76f8\u5173MUC1\u7684\u5355\u514b\u9686\u6297\u4f53\u3002<\/span><\/p>\n


<\/p>\n

Daiichi Sankyo\u7684\u80bf\u7624\u7814\u7a76\u4e0e\u5f00\u53d1\u6297\u4f53\u5076\u8054\u836f\u7269\u7279\u522b\u5de5\u4f5c\u7ec4\u526f\u603b\u88c1Tom Held\u8bf4\uff1a\u201c\u4ece\u5408\u4f5c\u81f3\u4eca\uff0c\u6211\u4eec\u73b0\u5728\u5df2\u7ecf\u5f00\u53d1\u4e86\u4e03\u79cd\u65b0\u578bADC\uff0c\u8fd9\u8868\u660e\u6211\u4eec\u81f4\u529b\u4e8e\u6700\u5927\u9650\u5ea6\u5730\u53d1\u6325\u6211\u4eecADC\u4e13\u6709\u7684\u6709\u6548\u8f7d\u8377\u548c\u8fde\u63a5\u5668\u6280\u672f\u7684\u6f5c\u529b\uff0c<\/span>\u4ee5\u5e2e\u52a9\u89e3\u51b3\u5168\u7403\u764c\u75c7\u60a3\u8005\u7684\u672a\u6ee1\u8db3\u9700\u6c42\u3002\u6211\u4eec\u5bf9\u4e0eGlycotope\u5408\u4f5c\u53d6\u5f97\u7684\u5feb\u901f\u8fdb\u5c55\u611f\u5230\u975e\u5e38\u5174\u594b\uff0c\u5e76\u671f\u5f85\u8fd9\u79cd\u6f5c\u5728\u7684\u9776\u5411\u80bf\u7624\u76f8\u5173MUC1\u9776\u70b9\u7684ADC\u7684\u4e34\u5e8a\u524d\u666f\u3002\u201d<\/p>\n


<\/p>\n

\u53c2\u8003\u6587\u732e\uff1a<\/p>\n

\u30101\u3011Daiichi Sankyo Enters Worldwide Licensing Agreement with Glycotope for Gatipotuzumab Antibody Drug Conjugate<\/span><\/p>\n

\u30102\u3011ADC\u5927\u84dd\u6d77\u518d\u6dfb\u529b\u5c06\uff01\u56fd\u5185\u9996\u4e2a\u4e2d\u7f8e\u53cc\u62a5\u6297\u4f53\u5076\u8054\u836f\u7269\u2014\u79d1\u4f26A166\u7f8e\u56fd\u5f00\u5c55I\/II\u4e34\u5e8a<\/span>   <\/span><\/span>CPhI\u5236\u836f\u5728\u7ebf <\/span> <\/p>\n

\u30103\u3011<\/span>2\u671f\u4e34\u5e8a\u5931\u5229\uff0cGlycotope\u643a\u624bDaiichi Sankyo\u7814\u53d1PankoMab-GEX \u7684ADC\u836f\u7269   \u6bcf\u65e5\u5355\u6297<\/p>\n


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\u5e7f\u800c\u544a\u4e4b<\/section>\n<\/section>\n


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\u2299 \u540c\u5199\u610f\u57f9\u8bad<\/span><\/p>\n

\u5199\u610f\u8bba\u575b\u4e28\u65b0\u836f\u4e2d\u7f8e\u53cc\u62a5\u4e4b\u5236\u5242\u6eb6\u51fa\u6280\u672f\u5f00\u53d1<\/a><\/span><\/p>\n

\u5199\u610f\u8bba\u575b\u4e28\u56fd\u9645\u89c4\u8303\u4e0b\u751f\u7269\u836f\u5168\u751f\u547d\u5468\u671f\u8d28\u91cf\u7ba1\u7406<\/a><\/span><\/p>\n

\u5199\u610f\u516c\u76ca\u4e28\u4eff\u5236\u836f\u4e00\u81f4\u6027\u8bc4\u4ef7\u5927\u76d8\u70b9\u4e0e\u603b\u51b3\u6218<\/a><\/p>\n

\u6ee1\u8db3IND\/NDA\u4e2d\u7f8e\u53cc\u62a5\u7684\u53e3\u670d\u65b0\u836f\u5236\u5242\u7814\u53d1<\/a><\/span><\/p>\n<\/section>\n<\/section>\n

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\"\u7b2c\u4e00\u4e09\u5171\u4e0eGlycotope\u8054\u5408\u5f00\u53d1gatipotuzumab\u7684\u6297\u4f53\u5076\u8054\u836f\u7269\"<\/p>\n

\u836f\u4e8b\u7eb5\u6a2a\u662f\u4e00\u4e2a\u5f00\u653e\uff0c\u7531\u81ea\u613f\u8005\u7ec4\u6210\u7684\u56e2\u4f53\uff0c\u73b0\u6709\u6210\u545838\u540d\uff0c\u5206\u522b\u4e3aVoyager88\uff08\u9b4f\u5229\u519b\uff09\uff0c\u96f7\u8bfa\u5c9b\uff0c\u4e09\u5206\u8bdd\uff0cHerman\uff0c\u6885\u5e0c\uff0c\u6587\u7af9\uff0cduke\uff0cyhqqqqq\uff0c\u5360\u5c0f\u5175\uff0c\u98ce\u4e00\u6837\u7684\u5c4e\u58f3\u90ce\uff0c\u9526\u5fc3\u7ee3\u53e3\uff0cflydp511\uff0c\u5de7\u5de7\uff0c\u4e91\u6c34\u9053\u4eba\uff0c\u9621\u4e0a\u964c\u964c\uff0c\u591a\u5df4\u80fa\uff0c\u745c\u513f\uff0cKailyn\uff0cSmall fish\uff0c\u5b50\u708e\uff0c\u514b\u683c\u83ab\uff0cVicky\uff0cPandada\uff0c\u83ab\u5306\u5306\uff0cSophia \uff0c\u4f9d\u7136\u7279\u96f7\u897f\uff0c\u5076\u9635\u96e8\uff0cAimee\uff0c\u4ed6\u5c71\u4e4b\u77f3\uff0c\u5510\u5c0f\u7396\uff0c\u96f6\u4e0b274\u2103\uff0cGloria\uff0cBreathless\uff0cLuffy\uff0c\u80e1\u4e0d\u559c\uff0c Helen\uff0c\u843d\u843d\uff0cSUNRISE\u3002\u6b22\u8fce\u6709\u5fd7\u4e4b\u58eb\u52a0\u5165\u6211\u4eec\u56e2\u961f\u3002\u6295\u7a3f\u3001\u5408\u4f5c\u3001\u52a0\u4e13\u4e1a\u7fa4\u8bf7\u52a0\u5fae\u4fe1442015666\uff0c\u836f\u4e8b\u7eb5\u6a2a\u4e8c\u5343\u4ebaQQ\u7fa422711855\u3002<\/span><\/p>\n

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\u59cb\u53d1\u4e8e\u5fae\u4fe1\u516c\u4f17\u53f7\uff1a \u836f\u4e8b\u7eb5\u6a2a <\/p>\n<\/blockquote>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

2018\u5e747\u670830\u65e5\uff0c\u7b2c\u4e00\u4e09\u5171\u682a\u5f0f\u4f1a\u793e\uff08Daiichi Sankyo\uff09\u548cGlycotope GmbH\uff08\u4ee5\u4e0b\u7b80\u79f0 […]<\/p>\n","protected":false},"author":1,"featured_media":25941,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[2],"tags":[],"_links":{"self":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/25940"}],"collection":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/comments?post=25940"}],"version-history":[{"count":1,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/25940\/revisions"}],"predecessor-version":[{"id":25948,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/25940\/revisions\/25948"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/media\/25941"}],"wp:attachment":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/media?parent=25940"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/categories?post=25940"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/tags?post=25940"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}