{"id":28225,"date":"2018-08-06T01:00:00","date_gmt":"2018-08-09T03:54:21","guid":{"rendered":"http:\/\/www.05921.net\/index.php\/2018\/08\/09\/%e6%af%8f%e5%91%a8%e6%8a%97%e4%bd%93%e8%8d%af%e8%ae%af20180730-20180805\/"},"modified":"2018-08-09T11:54:23","modified_gmt":"2018-08-09T03:54:23","slug":"%e6%af%8f%e5%91%a8%e6%8a%97%e4%bd%93%e8%8d%af%e8%ae%af20180730-20180805","status":"publish","type":"post","link":"https:\/\/www.05921.net\/index.php\/28225\/","title":{"rendered":"\u6bcf\u5468\u6297\u4f53\u836f\u8baf20180730-20180805"},"content":{"rendered":"<div class=\"bpp-post-content\">\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 15px;color: rgb(0, 82, 255);box-sizing: border-box !important;word-wrap: break-word !important;overflow-wrap: break-word !important;\">\u4f5c\u8005 l&nbsp;<strong style=\"max-width: 100%;color: rgb(62, 62, 62);font-size: 16px;line-height: 25.6px;box-sizing: border-box !important;word-wrap: break-word !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 15px;color: rgb(0, 82, 255);box-sizing: border-box !important;word-wrap: break-word !important;overflow-wrap: break-word !important;\">\u653e\u7fc1\u662f\u6c34\u8d27<\/span><\/strong><span style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"><\/span><\/span><\/strong><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 15px;color: rgb(0, 82, 255);box-sizing: border-box !important;word-wrap: break-word !important;overflow-wrap: break-word !important;\">\u7f16\u8f91&nbsp;<strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;overflow-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;overflow-wrap: break-word !important;\">l<\/span><\/strong>&nbsp;\u7ec6\u80de\u623f\u95f4<\/span><\/strong><\/span><\/strong><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 15px;\"><\/span><\/p>\n<section style=\"max-width: 100%;box-sizing: border-box;color: rgb(51, 51, 51);\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;overflow-wrap: break-word !important;\">\n<section class=\"\" style=\"margin-top: 10px;margin-bottom: 10px;max-width: 100%;box-sizing: border-box;text-align: center;word-wrap: break-word !important;overflow-wrap: break-word !important;\">\n<section class=\"\" style=\"padding: 4px;max-width: 100%;box-sizing: border-box;display: inline-block;background-color: rgb(249, 110, 87);word-wrap: break-word !important;overflow-wrap: break-word !important;\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;border-width: 1px;border-style: solid;border-color: white;width: 1.6em;height: 1.6em;font-size: 24px;line-height: 1.5em;color: rgb(255, 255, 255);word-wrap: break-word !important;overflow-wrap: break-word !important;\">\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;word-wrap: break-word !important;overflow-wrap: break-word !important;\">1<\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><strong><span style=\"font-size: 15px;\">Kymab\u516c\u5e03\u4e86\u6cbb\u7597\u81ea\u8eab\u514d\u75ab\u6027\u75be\u75c5\u7684\u65b0\u6297\u4f53KY1005\u7684\u521d\u6b65\u4e34\u5e8a\u7814\u7a76\u7ed3\u679c<\/span><\/strong><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 15px;\">7\u670830\u65e5\uff0c\u82f1\u56fd\uff0cKymab\u516c\u53f8\u4eca\u65e5\u5ba3\u5e03\u8be5\u516c\u53f8\u5728\u7814\u65b0\u836fKY1005\u7684I\u671f\u4e34\u5e8a\u7814\u7a76\u83b7\u5f97\u79ef\u6781\u8fdb\u5c55\uff0c\u5e76\u5c06\u7ee7\u7eed\u8fdb\u884c\u7279\u5e94\u6027\u76ae\u708e\u7684II\u671f\u4e34\u5e8a\u7814\u7a76\uff0c\u4e0e\u6b64\u540c\u65f6\u8fd8\u5c06\u5728\u79fb\u690d\u7269\u6297\u5bbf\u4e3b\u75c5\uff08<\/span><span style=\"font-size: 15px;\">GvHD<\/span><span style=\"font-size: 15px;\">\uff09\u7b49\u5176\u4ed6\u514d\u75ab\u75be\u75c5\u65b9\u9762\u8fdb\u884c\u7814\u7a76\u3002\u6b64\u6b21\u7684I\u671f\u4e34\u5e8a\u7ed3\u679c\u8868\u660e\uff0cKY1005\u5177\u6709\u826f\u597d\u7684\u5b89\u5168\u6027\u548c\u8010\u53d7\u6027\uff0c\u6b64\u5916\u7814\u7a76\u6570\u636e\u8fd8\u8bc1\u660eKY1005\u53ef\u4ee5\u963b\u6b62\u5065\u5eb7\u5fd7\u613f\u8005\u76ae\u80a4\u4e2dT\u7ec6\u80de\u9a71\u52a8\u7684\u708e\u75c7\u3002<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 15px;\"><br \/><\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 15px;\">KY1005\u80fd\u591f\u9ad8\u6548\u9776\u5411OX40L\uff0c\u5176\u53d7\u4f53OX40\u5728\u591a\u79cd\u708e\u75c7\u548c\u81ea\u8eab\u514d\u75ab\u75be\u75c5\u7684\u53d1\u5c55\u4e2d\u8d77\u7740\u6838\u5fc3\u4f5c\u7528\uff0c\u56e0\u6b64\u9776\u5411OX40L\u963b\u65ad\u5176\u4fe1\u53f7\u8f6c\u5bfc\u662f\u7ef4\u6301T\u7ec6\u80de\u53cd\u5e94\u7684\u53ef\u9760\u7b56\u7565\u3002<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 15px;\">&nbsp;<\/span><\/p>\n<section style=\"white-space: normal;max-width: 100%;box-sizing: border-box;color: rgb(51, 51, 51);\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;overflow-wrap: break-word !important;\">\n<section class=\"\" style=\"margin-top: 10px;margin-bottom: 10px;max-width: 100%;box-sizing: border-box;text-align: center;word-wrap: break-word !important;overflow-wrap: break-word !important;\">\n<section class=\"\" style=\"padding: 4px;max-width: 100%;box-sizing: border-box;display: inline-block;background-color: rgb(249, 110, 87);word-wrap: break-word !important;overflow-wrap: break-word !important;\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;border-width: 1px;border-style: solid;border-color: white;width: 1.6em;height: 1.6em;font-size: 24px;line-height: 1.5em;color: rgb(255, 255, 255);word-wrap: break-word !important;overflow-wrap: break-word !important;\">\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;word-wrap: break-word !important;overflow-wrap: break-word !important;\">2<\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<p style=\"text-align: justify;\"><strong><span style=\"font-size: 15px;\">EMA\u5bf9Keytruda\u8054\u5408\u5316\u7597\u4e00\u7ebf\u6cbb\u7597\u8f6c\u79fb\u6027\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u6301\u80af\u5b9a\u610f\u89c1<\/span><\/strong><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 15px;\">7\u670830\u65e5\uff0c\u7f8e\u56fd\uff0cMerck\u516c\u53f8\u4eca\u65e5\u5ba3\u5e03CHMP\u901a\u8fc7\u4e86\u4e00\u9879\u79ef\u6781\u7684\u610f\u89c1\uff0c\u5efa\u8bae\u6279\u51c6\u9ed8\u514b\u516c\u53f8\u7684Keytruda\u4e0e\u57f9\u7f8e\u66f2\u585e\u548c\u94c2\u5316\u7597\u8054\u5408\u4f7f\u7528\uff0c\u7528\u4e8e\u6ca1\u6709EGFR\u6216ALK\u57fa\u56e0\u7ec4\u7578\u53d8\u7684\u6210\u4eba\u8f6c\u79fb\u6027\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u4e00\u7ebf\u6cbb\u7597\u3002\u76ee\u524d\u4e34\u5e8a\u9700\u8981\u521b\u65b0\u7597\u6cd5\u6765\u63d0\u9ad8\u8f6c\u79fb\u6027\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u60a3\u8005\u7684\u603b\u4f53\u751f\u5b58\u7387\uff0c\u56e0\u4e3a\u80ba\u764c\u662f\u6b27\u6d32\u764c\u75c7\u6b7b\u4ea1\u7684\u4e3b\u8981\u539f\u56e0\u3002KEYNOTE-189\u7814\u7a76\u8868\u660e\uff0c\u4e0e\u5355\u72ec\u7684\u6807\u51c6\u62a4\u7406\u5316\u7597\u76f8\u6bd4\uff0c<span style=\"font-size: 15px;text-align: justify;\">Keytruda<\/span>\u4e0e\u5316\u7597\u8054\u5408\u4f7f\u7528\u5177\u6709\u663e\u8457\u7684\u751f\u5b58\u83b7\u76ca\u3002\u5728\u6b64\u4e4b\u524dCHMP\u8fd8\u91c7\u7eb3\u4e86\u4e00\u4e2a\u79ef\u6781\u7684\u610f\u89c1\uff0c\u5efa\u8bae\u6279\u51c6<span style=\"font-size: 15px;text-align: justify;\">Keytruda<\/span>\u4f5c\u4e3a\u5355\u4e00\u7597\u6cd5\u6cbb\u7597\u590d\u53d1\u6216\u8f6c\u79fb\u6027\u5934\u9888\u90e8\u9cde\u72b6\u7ec6\u80de\u764c\u3002\u8fd9\u4e24\u9879\u5efa\u8bae\u5c06\u7531\u6b27\u6d32\u8054\u76df\u8425\u9500\u6388\u6743\u59d4\u5458\u4f1a\u8fdb\u884c\u5ba1\u67e5\uff0c\u9884\u8ba1\u5c06\u57282018\u5e74\u7b2c\u4e09\u5b63\u5ea6\u5c31\u8fd9\u4e24\u9879\u5efa\u8bae\u505a\u51fa\u6700\u7ec8\u51b3\u5b9a\u3002<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 15px;\">&nbsp;<\/span><\/p>\n<section style=\"white-space: normal;max-width: 100%;box-sizing: border-box;color: rgb(51, 51, 51);\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;overflow-wrap: break-word !important;\">\n<section class=\"\" style=\"margin-top: 10px;margin-bottom: 10px;max-width: 100%;box-sizing: border-box;text-align: center;word-wrap: break-word !important;overflow-wrap: break-word !important;\">\n<section class=\"\" style=\"padding: 4px;max-width: 100%;box-sizing: border-box;display: inline-block;background-color: rgb(249, 110, 87);word-wrap: break-word !important;overflow-wrap: break-word !important;\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;border-width: 1px;border-style: solid;border-color: white;width: 1.6em;height: 1.6em;font-size: 24px;line-height: 1.5em;color: rgb(255, 255, 255);word-wrap: break-word !important;overflow-wrap: break-word !important;\">\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;word-wrap: break-word !important;overflow-wrap: break-word !important;\">3<\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<p style=\"text-align: justify;\"><strong><span style=\"font-size: 15px;\">Arcus Biosciences\u5ba3\u5e03\u542f\u52a8TIGIT\u6297\u4f53AB154\u7684I\u671f\u4e34\u5e8a\u7814\u7a76<\/span><\/strong><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 15px;\">7\u670830\u65e5\uff0c\u7f8e\u56fd\uff0cArcus Biosciences\u4eca\u65e5\u5ba3\u5e03\u5176\u5df2\u7ecf\u83b7\u5f97\u76d1\u7ba1\u90e8\u95e8\u7684\u6279\u51c6\uff0c\u53ef\u4ee5\u5f00\u59cb\u5176\u6297TIGIT\u6297\u4f53AB154\u7684I\u671f\u4e34\u5e8a\u8bd5\u9a8c\uff0c\u5e76\u9884\u8ba1\u5f88\u5feb\u5f00\u59cb\u7ed9\u60a3\u8005\u7528\u836f\u3002\u6b64\u9879I\u671f\u3001\u591a\u4e2d\u5fc3\u3001\u5f00\u653e\u6807\u7b7e\u8bd5\u9a8c\u65e8\u5728\u8bc4\u4f30AB154\u4f5c\u4e3a\u5355\u4e00\u7597\u6cd5\u5e76\u4e0e\u6297PD-1\u6297\u4f53AB122\u8054\u5408\u4f7f\u7528\u7684\u5b89\u5168\u6027\u3001\u836f\u4ee3\u52a8\u529b\u5b66\u3001\u836f\u6548\u5b66\u548c\u4e34\u5e8a\u6d3b\u6027\u3002\u521d\u671f\u4e34\u5e8a\u6570\u636e\u4e00\u65e6\u786e\u5b9a\u4e86AB154\u4f5c\u4e3a\u5355\u4e00\u7597\u6cd5\u548c\u4e0eAB122\u8054\u5408\u4f7f\u7528\u7684\u63a8\u8350\u5242\u91cf\uff0c\u8be5\u516c\u53f8\u5c06\u542f\u52a8\u6269\u5c55\u961f\u5217\u7814\u7a76\uff0c\u8bc4\u4f30\u8054\u5408\u7597\u6cd5\u5728\u9009\u5b9a\u80bf\u7624\u7c7b\u578b\u4e2d\u7684\u4e34\u5e8a\u7597\u6548\u3002<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 15px;\"><br \/><\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 15px;\">TIGIT\u662f\u4e00\u4e2a\u72ec\u7279\u7684\u514d\u75ab\u68c0\u67e5\u70b9\u86cb\u767d\uff0c\u5176\u53c2\u4e0e\u80bf\u7624\u5fae\u73af\u5883\u4e2d\u7684\u514d\u75ab\u6291\u5236\u548c\u6fc0\u6d3b\u901a\u8def\u7684\u4fe1\u53f7\u8f6c\u5bfc\u3002AB154\u4e34\u5e8a\u8bd5\u9a8c\u7684\u5f00\u59cb\u4ee3\u8868\u4e86\u8be5\u516c\u53f8\u7684\u4e00\u4e2a\u91cd\u8981\u91cc\u7a0b\u7891\uff0c\u56e0\u4e3a\u5176\u9884\u6d4b\u6297TIGIT\u6297\u4f53\u6709\u53ef\u80fd\u6210\u4e3a\u80bf\u7624\u514d\u75ab\u9886\u57df\u4e00\u79cd\u65b0\u7684\u91cd\u8981\u6cbb\u7597\u7b56\u7565\u3002<\/span><\/p>\n<p style=\"text-align: center;\"><img class=\"\"     style=\"width: 465px;height: 163px;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/08\/beepress2-1533786862.jpg\" alt=\"\u6bcf\u5468\u6297\u4f53\u836f\u8baf20180730-20180805\" title=\"\u6bcf\u5468\u6297\u4f53\u836f\u8baf20180730-20180805\"><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 15px;\"><br \/><\/span><\/p>\n<section style=\"white-space: normal;max-width: 100%;box-sizing: border-box;color: rgb(51, 51, 51);\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;overflow-wrap: break-word !important;\">\n<section class=\"\" style=\"margin-top: 10px;margin-bottom: 10px;max-width: 100%;box-sizing: border-box;text-align: center;word-wrap: break-word !important;overflow-wrap: break-word !important;\">\n<section class=\"\" style=\"padding: 4px;max-width: 100%;box-sizing: border-box;display: inline-block;background-color: rgb(249, 110, 87);word-wrap: break-word !important;overflow-wrap: break-word !important;\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;border-width: 1px;border-style: solid;border-color: white;width: 1.6em;height: 1.6em;font-size: 24px;line-height: 1.5em;color: rgb(255, 255, 255);word-wrap: break-word !important;overflow-wrap: break-word !important;\">\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;word-wrap: break-word !important;overflow-wrap: break-word !important;\">4<\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<p style=\"text-align: justify;\"><strong><span style=\"font-size: 15px;\">\u9884\u9632\u504f\u5934\u75db\u65b0\u7597\u6cd5Aimovig\u00ae\u6b63\u5f0f\u5728\u6b27\u76df\u83b7\u6279<\/span><\/strong><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 15px;\">7\u670831\u65e5\uff0c\u745e\u58eb\uff0c\u8bfa\u534e\u516c\u53f8\u4eca\u65e5\u5ba3\u5e03\u6b27\u76df\u59d4\u5458\u4f1a\u5df2\u7ecf\u6279\u51c6Aimovig\uff08<\/span><span style=\"font-size: 15px;\">Erenumab<\/span><span style=\"font-size: 15px;\">\uff09\u7528\u4e8e\u6bcf\u6708\u7ecf\u5386\u56db\u5929\u4ee5\u4e0a\u504f\u5934\u75db\u7684\u6210\u5e74\u60a3\u8005\u504f\u5934\u75db\u7684\u9884\u9632\u6cbb\u7597\u3002Aimovig\u662f\u552f\u4e00\u4e00\u79cd\u4e13\u95e8\u8bbe\u8ba1\u7528\u4e8e\u504f\u5934\u75db\u9884\u9632\u6cbb\u7597\u7684\u65b9\u6cd5\uff0c\u5b83\u901a\u8fc7\u963b\u65ad\u964d\u9499\u7d20\u57fa\u56e0\u76f8\u5173\u80bd\u53d7\u4f53(CGRP-R)\u53d7\u4f53\u53d1\u6325\u4f5c\u7528\uff0c\u8fd9\u79cd\u53d7\u4f53\u5728\u4ecb\u5bfc\u504f\u5934\u75db\u4e2d\u8d77\u7740\u5173\u952e\u4f5c\u7528\u3002\u57282600\u540d\u60a3\u8005\u7684\u5e7f\u6cdb\u4e34\u5e8a\u9879\u76ee\u4e2d\uff0c\u670d\u7528Aimovig\u7684\u60a3\u8005\u6bcf\u6708\u504f\u5934\u75db\u5929\u6570\u663e\u8457\u51cf\u5c11\uff0c\u5176\u5b89\u5168\u6027\u548c\u8010\u53d7\u6027\u7c7b\u4f3c\u4e8e\u5b89\u6170\u5242\u3002<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 15px;\">&nbsp;<\/span><\/p>\n<section style=\"white-space: normal;max-width: 100%;box-sizing: border-box;color: rgb(51, 51, 51);\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;overflow-wrap: break-word !important;\">\n<section class=\"\" style=\"margin-top: 10px;margin-bottom: 10px;max-width: 100%;box-sizing: border-box;text-align: center;word-wrap: break-word !important;overflow-wrap: break-word !important;\">\n<section class=\"\" style=\"padding: 4px;max-width: 100%;box-sizing: border-box;display: inline-block;background-color: rgb(249, 110, 87);word-wrap: break-word !important;overflow-wrap: break-word !important;\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;border-width: 1px;border-style: solid;border-color: white;width: 1.6em;height: 1.6em;font-size: 24px;line-height: 1.5em;color: rgb(255, 255, 255);word-wrap: break-word !important;overflow-wrap: break-word !important;\">\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;word-wrap: break-word !important;overflow-wrap: break-word !important;\">5<\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<p style=\"text-align: justify;\"><strong><span style=\"font-size: 15px;\">\u8f89\u745e\u516c\u53f8\u7684\u751f\u7269\u7c7b\u4f3c\u836fTRAZIMERA\u2122\uff08T<\/span><\/strong><strong><span style=\"font-size: 15px;\">rastuzumab<\/span><\/strong><strong><span style=\"font-size: 15px;\">\uff09\u5728\u6b27\u6d32\u83b7\u6279<\/span><\/strong><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 15px;\">7\u670831\u65e5\uff0c\u7f8e\u56fd\uff0cPfizer\u4eca\u5929\u5ba3\u5e03\u6b27\u76df\u59d4\u5458\u4f1a\u5df2\u7ecf\u6279\u51c6\u4e86TRAZIMERA\uff08T<\/span><span style=\"font-size: 15px;\">rastuzumab<\/span><span style=\"font-size: 15px;\">\uff09\u4e0a\u5e02\u7528\u4e8e\u6cbb\u7597\u4eba\u8868\u76ae\u751f\u957f\u56e0\u5b50\u8fc7\u5ea6\u8868\u8fbe\u7684\u4e73\u817a\u764c\u548c\u8f6c\u79fb\u6027\u80c3\u6216\u80c3\u98df\u7ba1\u8fde\u63a5\u817a\u764c\u3002TRAZIMERA\u7684\u4e0a\u5e02\u5c06\u80fd\u591f\u5e2e\u52a9\u66f4\u591a\u4e73\u817a\u764c\u548c\u80c3\u764c\u60a3\u8005\uff0c\u5728\u4e0d\u5f71\u54cd\u836f\u54c1\u8d28\u91cf\u3001\u529f\u6548\u548c\u5b89\u5168\u6027\u7684\u60c5\u51b5\u4e0b\uff0c\u4e3a\u6b27\u6d32\u5404\u5730\u7684\u60a3\u8005\u548c\u533b\u751f\u63d0\u4f9b\u66f4\u591a\u6709\u4ef7\u503c\u670d\u52a1\u3002<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 15px;\">&nbsp;<\/span><\/p>\n<section style=\"white-space: normal;max-width: 100%;box-sizing: border-box;color: rgb(51, 51, 51);\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;overflow-wrap: break-word !important;\">\n<section class=\"\" style=\"margin-top: 10px;margin-bottom: 10px;max-width: 100%;box-sizing: border-box;text-align: center;word-wrap: break-word !important;overflow-wrap: break-word !important;\">\n<section class=\"\" style=\"padding: 4px;max-width: 100%;box-sizing: border-box;display: inline-block;background-color: rgb(249, 110, 87);word-wrap: break-word !important;overflow-wrap: break-word !important;\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;border-width: 1px;border-style: solid;border-color: white;width: 1.6em;height: 1.6em;font-size: 24px;line-height: 1.5em;color: rgb(255, 255, 255);word-wrap: break-word !important;overflow-wrap: break-word !important;\">\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;word-wrap: break-word !important;overflow-wrap: break-word !important;\">6<\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<p style=\"text-align: justify;\"><strong><span style=\"font-size: 15px;\">\u6b27\u76df\u59d4\u5458\u4f1a\u6279\u51c6Opdivo\uff08N<\/span><\/strong><strong><span style=\"font-size: 15px;\">ivolumab<\/span><\/strong><strong><span style=\"font-size: 15px;\">\uff09\u7528\u4e8e\u9ed1\u8272\u7d20\u7624\u60a3\u8005\u672f\u540e\u7684\u8f85\u52a9\u6cbb\u7597<\/span><\/strong><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 15px;\">7\u670831\u65e5\uff0c\u7f8e\u56fd\uff0cBMS\u516c\u53f8\u4eca\u65e5\u5ba3\u5e03\u6b27\u76df\u59d4\u5458\u4f1a\u5df2\u7ecf\u6279\u51c6\u4e86Opdivo\u7528\u4e8e\u4f34\u6709\u6dcb\u5df4\u7ed3\u8f6c\u79fb\u7684\u9ed1\u8272\u7d20\u7624\u60a3\u8005\u672f\u540e\u7684\u8f85\u52a9\u6cbb\u7597\uff0c\u8fd9\u4e00\u9002\u5e94\u75c7\u5bf9\u4e8eBRAF\u7a81\u53d8\u578b\u548c\u91ce\u751f\u578b\u7684\u9ed1\u8272\u7d20\u7624\u5747\u9002\u7528\u3002\u901a\u8fc7\u8fd9\u4e00\u51b3\u5b9a\uff0cOpdivo\u6210\u4e3a\u7b2c\u4e00\u4e2a\u4e5f\u662f\u552f\u4e00\u4e00\u4e2a\u5728\u8f85\u52a9\u6cbb\u7597\u4e2d\u83b7\u5f97\u6b27\u76df\u6279\u51c6\u7684PD-1\u7597\u6cd5\uff0c\u8be5\u836f\u76ee\u524d\u5728\u6b27\u6d32\u7684\u516d\u79cd\u4e0d\u540c\u80bf\u7624\u7c7b\u578b\u4e2d\u83b7\u5f97\u4e86\u516b\u4e2a\u9002\u5e94\u75c7\u3002<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 15px;\"><br \/><\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 15px;\">III\u671f\u548cIV\u671f\u9ed1\u8272\u7d20\u7624\u60a3\u8005\u5728\u624b\u672f\u5207\u9664\u540e\u6709\u590d\u53d1\u7684\u9ad8\u98ce\u9669\uff0c\u56e0\u6b64\u9700\u8981\u6709\u6548\u7684\u5e72\u9884\u63aa\u65bd\u6765\u9632\u6b62\u590d\u53d1\uff0c\u5df2\u6709\u7684III\u671f\u4e34\u5e8a\u6570\u636e\u5df2\u7ecf\u8bc1\u5b9e<span style=\"font-size: 15px;text-align: justify;\">Opdivo<\/span>\u5bf9\u4e8e\u4e0d\u540c\u80bf\u7624\u7c7b\u578b\u7684\u60a3\u8005\u5747\u80fd\u83b7\u76ca\uff0c\u5bf9\u4e8e\u5ef6\u7f13\u80bf\u7624\u590d\u53d1\u7597\u6548\u663e\u8457\u30022017\u5e7412\u6708\uff0cFDA\u6279\u51c6\u4e86Opdivo\u4f5c\u4e3a\u8f85\u52a9\u7597\u6cd5\uff0c\u7528\u4e8e\u6cbb\u7597\u60a3\u6709\u6dcb\u5df4\u7ed3\u8f6c\u79fb\u7684\u9ed1\u8272\u7d20\u7624\u60a3\u8005\uff0cOpdivo\u6b64\u6b21\u5728\u6b27\u6d32\u7684\u83b7\u6279\u6709\u52a9\u4e8e\u589e\u5f3a\u60a3\u8005\u7684\u4fe1\u5fc3\uff0c\u964d\u4f4e\u521d\u6b21\u6cbb\u7597\u540e\u9ed1\u7d20\u7624\u590d\u53d1\u548c\u53d1\u5c55\u7684\u98ce\u9669\u3002<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 15px;\">&nbsp;<\/span><\/p>\n<section style=\"white-space: normal;max-width: 100%;box-sizing: border-box;color: rgb(51, 51, 51);\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;overflow-wrap: break-word !important;\">\n<section class=\"\" style=\"margin-top: 10px;margin-bottom: 10px;max-width: 100%;box-sizing: border-box;text-align: center;word-wrap: break-word !important;overflow-wrap: break-word !important;\">\n<section class=\"\" style=\"padding: 4px;max-width: 100%;box-sizing: border-box;display: inline-block;background-color: rgb(249, 110, 87);word-wrap: break-word !important;overflow-wrap: break-word !important;\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;border-width: 1px;border-style: solid;border-color: white;width: 1.6em;height: 1.6em;font-size: 24px;line-height: 1.5em;color: rgb(255, 255, 255);word-wrap: break-word !important;overflow-wrap: break-word !important;\">\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;word-wrap: break-word !important;overflow-wrap: break-word !important;\">7<\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<p style=\"text-align: justify;\"><strong><span style=\"font-size: 15px;\">\u4e09\u53f6\u8349\u751f\u7269\u5236\u836f\u5728\u4e2d\u56fd\u542f\u52a8\u4e86Etanercept\u4eff\u5236\u836fSCB-808\u7684I\u671f\u4e34\u5e8a\u7814\u7a76<\/span><\/strong><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 15px;\">8\u67081\u65e5\uff0c\u4e2d\u56fd\uff0c\u4e09\u53f6\u8349\u751f\u7269\u5236\u836f\u4eca\u5929\u5ba3\u5e03\u5728\u4e2d\u56fd\u8fdb\u884c\u7684SCB-808\u7684I\u671f\u4e34\u5e8a\u8bd5\u9a8c\u5165\u7ec4\u9996\u4f8b\u53d7\u8bd5\u8005\u3002\u8be5\u836f\u7269\u662f\u4e00\u79cd\u9884\u5145\u586b\u5c0f\u5bb9\u91cf\u6ce8\u5c04\u6db2Etanercept\uff08\u4f9d\u90a3\u897f\u666e\uff09\u7684\u751f\u7269\u7c7b\u4f3c\u836f\uff0c\u7528\u4e8e\u6cbb\u7597\u7c7b\u98ce\u6e7f\u6027\u5173\u8282\u708e\u548c\u5176\u4ed6\u81ea\u8eab\u514d\u75ab\u6027\u75be\u75c5\u3002SCB-808\u5728\u4e2d\u56fd\u5f00\u5c55\u7684I\u671f\u4e34\u5e8a\u8bd5\u9a8c\u65e8\u5728\u8bc4\u4f30\u901a\u8fc7\u76ae\u4e0b\u6ce8\u5c04SCB-808\u548c\u539f\u7814\u836f\u7684\u836f\u4ee3\u52a8\u529b\u5b66\u7279\u6027\u3001\u5b89\u5168\u6027\u3001\u548c\u514d\u75ab\u539f\u6027\u3002<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 15px;\">&nbsp;<\/span><\/p>\n<section style=\"white-space: normal;max-width: 100%;box-sizing: border-box;color: rgb(51, 51, 51);\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;overflow-wrap: break-word !important;\">\n<section class=\"\" style=\"margin-top: 10px;margin-bottom: 10px;max-width: 100%;box-sizing: border-box;text-align: center;word-wrap: break-word !important;overflow-wrap: break-word !important;\">\n<section class=\"\" style=\"padding: 4px;max-width: 100%;box-sizing: border-box;display: inline-block;background-color: rgb(249, 110, 87);word-wrap: break-word !important;overflow-wrap: break-word !important;\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;border-width: 1px;border-style: solid;border-color: white;width: 1.6em;height: 1.6em;font-size: 24px;line-height: 1.5em;color: rgb(255, 255, 255);word-wrap: break-word !important;overflow-wrap: break-word !important;\">\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;word-wrap: break-word !important;overflow-wrap: break-word !important;\">8<\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<p style=\"text-align: justify;\"><strong><span style=\"font-size: 15px;\">Eylea\u6cbb\u7597\u5e74\u9f84\u76f8\u5173\u6027\u9ec4\u6591\u53d8\u6027\u7684\u65b0\u7597\u6cd5\u5728\u6b27\u6d32\u83b7\u6279<\/span><\/strong><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 15px;\">8\u67082\u65e5\uff0c\u5fb7\u56fd\uff0c\u62dc\u8033\u516c\u53f8\u4eca\u5929\u5ba3\u5e03\u6b27\u76df\u59d4\u5458\u4f1a\u5df2\u7ecf\u6279\u51c6\u4e86\u4e00\u79cd\u65b0\u7684Eylea\u7ed9\u836f\u65b9\u6cd5\uff0c\u4f7f\u5f97\u5728\u9762\u5bf9\u65b0\u751f\u8840\u7ba1\u5e74\u9f84\u76f8\u5173\u6027\u9ec4\u6591\u53d8\u6027\uff08<\/span><span style=\"font-size: 15px;\">nAMD<\/span><span style=\"font-size: 15px;\">\uff09\u60a3\u8005\u65f6\uff0c\u80fd\u591f\u5c06\u79ef\u6781\u6cbb\u7597\u4e0e\u5ef6\u957f\u6ce8\u5c04\u7ed9\u836f\u95f4\u9694\u7597\u6cd5\u76f8\u7ed3\u5408\u3002\u65b0\u7684\u6cbb\u7597\u65b9\u6848\u5141\u8bb8\u5bf9\u4e8e\u5df2\u7ecf\u6cbb\u7597\u4e00\u5e74\u7684\u60a3\u8005\uff0c\u4e34\u5e8a\u533b\u751f\u6839\u636e\u89c6\u89c9\u6539\u5584\u72b6\u51b5\u5ef6\u957f\u60a3\u8005\u7684\u4e2a\u4f53\u6ce8\u5c04\u7ed9\u836f\u95f4\u9694\u3002\u65b0\u751f\u8840\u7ba1\u6027\u5e74\u9f84\u76f8\u5173\u6027\u9ec4\u6591\u53d8\u6027\u5bf9\u60a3\u8005\u7684\u751f\u6d3b\u4f1a\u4ea7\u751f\u6bc1\u706d\u6027\u7684\u5f71\u54cd\uff0c\u6b64\u6b21\u9488\u5bf9Eylea\u7684\u65b0\u6cbb\u7597\u65b9\u6848\u6709\u53ef\u80fd\u5728\u7b2c\u4e8c\u5e74\u5c06\u90e8\u5206\u60a3\u8005\u7684\u6ce8\u5c04\u6b21\u6570\u548c\u4e34\u5e8a\u8bbf\u89c6\u6b21\u6570\u51cf\u5c11\u5230\u56db\u6b21\u4ee5\u5185\uff0c\u5728\u51cf\u5c11\u6cbb\u7597\u6b21\u6570\u7684\u540c\u65f6\u4ecd\u7136\u4fdd\u6301\u826f\u597d\u7684\u89c6\u529b\u3002<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 15px;\">&nbsp;<\/span><\/p>\n<section style=\"white-space: normal;max-width: 100%;box-sizing: border-box;color: rgb(51, 51, 51);\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;overflow-wrap: break-word !important;\">\n<section class=\"\" style=\"margin-top: 10px;margin-bottom: 10px;max-width: 100%;box-sizing: border-box;text-align: center;word-wrap: break-word !important;overflow-wrap: break-word !important;\">\n<section class=\"\" style=\"padding: 4px;max-width: 100%;box-sizing: border-box;display: inline-block;background-color: rgb(249, 110, 87);word-wrap: break-word !important;overflow-wrap: break-word !important;\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;border-width: 1px;border-style: solid;border-color: white;width: 1.6em;height: 1.6em;font-size: 24px;line-height: 1.5em;color: rgb(255, 255, 255);word-wrap: break-word !important;overflow-wrap: break-word !important;\">\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;word-wrap: break-word !important;overflow-wrap: break-word !important;\">9<\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<p style=\"text-align: justify;\"><strong><span style=\"font-size: 15px;\">LENVIMA\uff08L<\/span><\/strong><strong><span style=\"font-size: 15px;\">envatinib<\/span><\/strong><strong><span style=\"font-size: 15px;\">\uff09\u8054\u5408Ke&nbsp;ytruda\u7597\u6cd5\u518d\u6b21\u83b7\u5f97\u7a81\u7834\u6027\u7597\u6cd5\u8ba4\u8bc1<\/span><\/strong><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 15px;\">7\u670831\u65e5\uff0c\u65e5\u672c\u548c\u7f8e\u56fd\uff0cEisai\u548cMerck\u516c\u53f8\u4eca\u65e5\u5ba3\u5e03FDA\u5df2\u7ecf\u6388\u4e88\u4e86Eisai\u7684\u53e3\u670d\u6fc0\u9176\u6291\u5236\u5242LENVIMA\uff08L<\/span><span style=\"font-size: 15px;\">envatinib<\/span><span style=\"font-size: 15px;\">\uff09\u4e0eMerck\u7684Keytruda\u8054\u5408\u6cbb\u7597\u665a\u671f\/\u8f6c\u79fb\u6027\u975e\u5fae\u536b\u661f\u4e0d\u7a33\u5b9a\u6027\u9ad8\/\u9519\u914d\u4fee\u590d\u578b\u5b50\u5bab\u5185\u819c\u764c\uff08EC\uff09\u7a81\u7834\u6027\u7597\u6cd5\u79f0\u53f7\u3002\u8fd9\u9879\u7a81\u7834\u6027\u7597\u6cd5\u7684\u8ba4\u8bc1\u662f\u57fa\u4e8e\u4e00\u9879\u6709\u5173\u5b50\u5bab\u5185\u819c\u764c\u961f\u5217\u7814\u7a76\u7684\u4e2d\u671f\u7ed3\u679c\uff0c\u8be5\u7814\u7a76\u5df2\u7ecf\u6b63\u5f0f\u8054\u5408\u7597\u6cd5\u80fd\u591f\u83b7\u5f97\u6ee1\u610f\u7684\u4e34\u5e8a\u7597\u6548\u540c\u65f6\u5e76\u4e0d\u589e\u52a0\u989d\u5916\u7684\u4e0d\u826f\u53cd\u5e94\u548c\u5e76\u53d1\u75c7\u3002<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 15px;\">&nbsp;<\/span><\/p>\n<section style=\"white-space: normal;max-width: 100%;box-sizing: border-box;color: rgb(51, 51, 51);\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;overflow-wrap: break-word !important;\">\n<section class=\"\" style=\"margin-top: 10px;margin-bottom: 10px;max-width: 100%;box-sizing: border-box;text-align: center;word-wrap: break-word !important;overflow-wrap: break-word !important;\">\n<section class=\"\" style=\"padding: 4px;max-width: 100%;box-sizing: border-box;display: inline-block;background-color: rgb(249, 110, 87);word-wrap: break-word !important;overflow-wrap: break-word !important;\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;border-width: 1px;border-style: solid;border-color: white;width: 1.6em;height: 1.6em;font-size: 24px;line-height: 1.5em;color: rgb(255, 255, 255);word-wrap: break-word !important;overflow-wrap: break-word !important;\">\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;word-wrap: break-word !important;overflow-wrap: break-word !important;\">10<\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<p style=\"text-align: justify;\"><strong><span style=\"font-size: 15px;\">Xcovery\u5ba3\u5e03Vorolanib\u8054\u5408Nivolumab\u6cbb\u7597\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u6216\u80f8\u817a\u764c\u7684\u4e34\u5e8a\u8bd5\u9a8c\u5df2\u7ecf\u6709\u60a3\u8005\u5165\u7ec4<\/span><\/strong><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 15px;\">8\u67081\u65e5\uff0c\u7f8e\u56fd\uff0cXcovery\u516c\u53f8\u4eca\u65e5\u5ba3\u5e03\u8bc4\u4f30Vorolanib\u8054\u5408Nivolumab\u6cbb\u7597\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u6216\u80f8\u817a\u764c\u6709\u6548\u6027\u548c\u5b89\u5168\u6027\u7684I\/II\u671f\u4e34\u5e8a\u7814\u7a76\u5df2\u7ecf\u6709\u60a3\u8005\u5165\u7ec4\u53d7\u8bd5\u3002Vorolanib\u662f\u65b0\u4e00\u4ee3EGFR\u6291\u5236\u5242\uff0cNivolumab\u662f\u5df2\u7ecf\u83b7\u6279\u591a\u79cd\u9002\u5e94\u75c7\u7684PD-1\u6297\u4f53\u836f\u7269\u3002Nivolmab\u662f\u80fd\u591f\u8ba9\u591a\u79cd\u764c\u75c7\u60a3\u8005\u663e\u8457\u83b7\u76ca\u7684PD-1\u6297\u4f53\uff0c\u5176\u5b83\u901a\u8fc7\u6fc0\u6d3b\u75c5\u4eba\u81ea\u8eab\u7684\u514d\u75ab\u7cfb\u7edf\u6765\u653b\u51fb\u80bf\u7624\uff0c\u800c\u96be\u6cbb\u6027\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u60a3\u8005\u5bf9\u68c0\u67e5\u70b9\u6291\u5236\u5242\u6cbb\u7597\u5e94\u7b54\u4e0d\u4f73\uff0cVorolanib\u53ef\u4ee5\u8c03\u8282\u80bf\u7624\u5fae\u73af\u5883\uff0c\u5e76\u589e\u5f3a\u68c0\u67e5\u70b9\u6291\u5236\u5242\u5982Nivolmab\u7684\u529f\u6548<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 15px;\">&nbsp;<\/span><\/p>\n<section style=\"white-space: normal;max-width: 100%;box-sizing: border-box;color: rgb(51, 51, 51);\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;overflow-wrap: break-word !important;\">\n<section class=\"\" style=\"margin-top: 10px;margin-bottom: 10px;max-width: 100%;box-sizing: border-box;text-align: center;word-wrap: break-word !important;overflow-wrap: break-word !important;\">\n<section class=\"\" style=\"padding: 4px;max-width: 100%;box-sizing: border-box;display: inline-block;background-color: rgb(249, 110, 87);word-wrap: break-word !important;overflow-wrap: break-word !important;\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;border-width: 1px;border-style: solid;border-color: white;width: 1.6em;height: 1.6em;font-size: 24px;line-height: 1.5em;color: rgb(255, 255, 255);word-wrap: break-word !important;overflow-wrap: break-word !important;\">\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;word-wrap: break-word !important;overflow-wrap: break-word !important;\">11<\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<p style=\"text-align: justify;\"><strong><span style=\"font-size: 15px;\">FDA\u6388\u4e88ArmaGen\u516c\u53f8\u7684AGT-184\u5b64\u513f\u836f\u8d44\u683c<\/span><\/strong><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 15px;\">8\u67082\u65e5\uff0c\u7f8e\u56fd\uff0cArmaGen\u516c\u53f8\u4eca\u65e5\u5ba3\u5e03FDA\u5df2\u7ecf\u6388\u4e88AGT-184\u6cbb\u7597IIIA\u578b\u7c98\u591a\u7cd6\u75c5\u5b64\u513f\u836f\u8d44\u683c\u3002IIIA\u578b\u7c98\u591a\u7cd6\u75c5\uff08<\/span><span style=\"font-size: 15px;\">MPS IIIA<\/span><span style=\"font-size: 15px;\">\uff09\u662f\u6eb6\u9176\u4f53\u50a8\u5b58\u75be\u75c5\uff08<\/span><span style=\"font-size: 15px;\">LSD<\/span><span style=\"font-size: 15px;\">\uff09\uff0c\u7531\u7f16\u7801N-\u78fa\u57fa\u8461\u7cd6\u80fa\u78fa\u57fa\u6c34\u89e3\u9176\uff08<\/span><span style=\"font-size: 15px;\">SGSH<\/span><span style=\"font-size: 15px;\">\uff09\u7684\u57fa\u56e0\u7f3a\u5931\u5f15\u8d77\uff0c\u8fd9\u5bfc\u81f4\u590d\u6742\u7cd6\u805a\u5408\u7269\u5728\u5927\u8111\u4e2d\u79ef\u7d2f\uff0c\u6700\u7ec8\u5bfc\u81f4\u60a3\u8005\u7684\u667a\u529b\u9010\u6e10\u4e27\u5931\u3002AGT-184\u662f\u4e00\u79cdIgG-SGSH\u878d\u5408\u86cb\u767d\u7684\u9176\u66ff\u4ee3\u7597\u6cd5\uff0c\u7531\u6297\u4eba\u80f0\u5c9b\u7d20\u53d7\u4f53\u5355\u514b\u9686\u6297\u4f53IgG\u7aef\u548cSHSH\u9176\u5076\u8054\u800c\u6210\u3002\u5176\u4e2d\u80f0\u5c9b\u7d20\u53d7\u4f53\u6297\u4f53\u7aef\u8d1f\u8d23\u8c03\u89e3AGT-184\u878d\u5408\u86cb\u767d\u7684\u8de8\u819c\u8f6c\u8fd0\uff0c\u4f7f\u5176\u80fd\u591f\u987a\u5229\u901a\u8fc7\u8840\u8111\u5c4f\u969c\uff0c\u9884\u8ba1\u8be5\u836f\u5c06\u57282019\u5e74\u5728\u5168\u7403\u5404\u5730\u63d0\u4ea4\u65b0\u836f\u4e34\u5e8a\u8bd5\u9a8c\u7533\u8bf7\u3002<\/span><\/p>\n<p style=\"text-align: center;\"><img class=\"\"     style=\"width: 433px;height: 329px;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/08\/beepress5-1533786862.jpg\" alt=\"\u6bcf\u5468\u6297\u4f53\u836f\u8baf20180730-20180805\" title=\"\u6bcf\u5468\u6297\u4f53\u836f\u8baf20180730-20180805\"><\/p>\n<p><\/p>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 15px;box-sizing: border-box !important;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;color: rgb(192, 0, 0);font-family: \u5fae\u8f6f\u96c5\u9ed1;font-size: 14px;letter-spacing: 0.544px;text-align: center;widows: 1;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\">\u6b22\u8fce\u548c\u6211\u4eec\u4e00\u8d77\u53d1\u73b0\u6297\u4f53\u6e90\u52a8\u529b\uff0c\u201c<\/span><\/strong><\/span><strong style=\"max-width: 100%;color: rgb(192, 0, 0);font-family: \u5fae\u8f6f\u96c5\u9ed1;font-size: 14px;letter-spacing: 0.544px;text-align: center;widows: 1;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\">\u9605\u8bfb\u539f\u6587<\/span><\/strong><strong style=\"max-width: 100%;color: rgb(192, 0, 0);font-family: \u5fae\u8f6f\u96c5\u9ed1;font-size: 14px;letter-spacing: 0.544px;text-align: center;widows: 1;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\">\u201d\u62a5\u540d\u53c2\u52a0\u6297\u4f53\u836f\u7814\u53d1\u8bfe\u7a0b<\/span><\/strong><\/p>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 15px;box-sizing: border-box !important;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;color: rgb(192, 0, 0);font-family: \u5fae\u8f6f\u96c5\u9ed1;font-size: 14px;letter-spacing: 0.544px;text-align: center;widows: 1;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"><\/span><\/strong><\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;word-wrap: break-word !important;\"><img class=\"\"       style=\"box-sizing: border-box !important;word-wrap: break-word !important;visibility: visible !important;width: auto !important;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/08\/beepress10-1533786862.jpeg\" alt=\"\u6bcf\u5468\u6297\u4f53\u836f\u8baf20180730-20180805\" title=\"\u6bcf\u5468\u6297\u4f53\u836f\u8baf20180730-20180805\"><\/p>\n<p style=\"max-width: 100%;min-height: 1em;text-align: center;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;color: rgb(0, 209, 0);font-size: 14px;box-sizing: border-box !important;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\">\u6b22\u8fce\u52a0\u5165\u5c0f\u7f16\u56e2\u961f\u6210\u4e3a\u5c0f\u7f16\u4e00\u5458<\/strong><\/span><br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"><\/p>\n<p style=\"max-width: 100%;min-height: 1em;text-align: center;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;color: rgb(0, 209, 0);box-sizing: border-box !important;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;color: rgb(170, 33, 94);line-height: 25.6px;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;color: rgb(0, 209, 0);font-size: 14px;box-sizing: border-box !important;word-wrap: break-word !important;\">\u8bf7\u52a0\u5c0f\u7f16\u5fae\u4fe1\u53f7\uff1awuwenjun7237<\/span><\/strong><\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;text-align: center;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;color: rgb(0, 209, 0);font-size: 14px;box-sizing: border-box !important;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;color: rgb(170, 33, 94);line-height: 25.6px;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;color: rgb(0, 209, 0);line-height: 25.6px;box-sizing: border-box !important;word-wrap: break-word !important;\">\u5982\u6709\u6280\u672f\u89e3\u8bfb\u3001\u884c\u4e1a\u6d1e\u89c1\u613f\u610f\u5206\u4eab<\/span><\/strong><\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;text-align: center;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;color: rgb(0, 209, 0);font-size: 14px;box-sizing: border-box !important;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;color: rgb(170, 33, 94);line-height: 25.6px;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;color: rgb(0, 209, 0);line-height: 25.6px;box-sizing: border-box !important;word-wrap: break-word !important;\">\u6b22\u8fce\u6295\u7a3f\u5230\u5c0f\u7f16\u90ae\u7bb1\uff1a<strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\">wuwj06@163.com<\/strong><\/span><\/strong><\/span><strong style=\"max-width: 100%;color: rgb(170, 33, 94);line-height: 25.6px;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 14px;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;line-height: 25.6px;font-size: 12px;box-sizing: border-box !important;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"><\/strong><\/span><span style=\"max-width: 100%;line-height: 25.6px;box-sizing: border-box !important;word-wrap: break-word !important;\"><\/span><\/span><\/strong><\/p>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;word-wrap: break-word !important;\"><\/p>\n<section style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\">\n<section style=\"margin-top: 0.5em;margin-bottom: 0.5em;max-width: 100%;text-align: center;box-sizing: border-box !important;word-wrap: break-word !important;\">\n<section style=\"margin: -0.9em auto 0.9em;max-width: 100%;width: 0.6em;height: 0.6em;box-sizing: border-box !important;word-wrap: break-word !important;\">\n<section style=\"margin-left: 1px;max-width: 100%;border-radius: 100%;width: 9.59px;height: 9.59px;background-color: rgb(170, 33, 94);box-sizing: border-box !important;word-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"><\/section>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\">\n<section style=\"margin-top: 10px;margin-bottom: 10px;padding-left: 4px;max-width: 100%;text-align: center;box-sizing: border-box !important;word-wrap: break-word !important;\">\n<section style=\"margin-bottom: 0.2em;max-width: 100%;width: 666px;vertical-align: bottom;display: inline-block;box-sizing: border-box !important;word-wrap: break-word !important;\">\n<section style=\"max-width: 100%;width: 599.39px;border-top: 1px solid rgb(170, 33, 94);box-sizing: border-box !important;word-wrap: break-word !important;\"><\/section>\n<section style=\"margin-top: -4px;margin-right: -4px;max-width: 100%;border-radius: 100%;width: 8px;height: 8px;background-color: rgb(170, 33, 94);box-sizing: border-box !important;word-wrap: break-word !important;\"><\/section>\n<\/section>\n<section style=\"margin-top: -1.5em;max-width: 100%;text-align: right;box-sizing: border-box !important;word-wrap: break-word !important;\">\n<section style=\"max-width: 100%;border-radius: 100%;width: 2em;height: 2em;text-align: center;color: rgb(255, 255, 255);line-height: 2em;vertical-align: top;display: inline-block;background-color: rgb(170, 33, 94);box-sizing: border-box !important;word-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;color: rgb(170, 33, 94);box-sizing: border-box !important;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 18px;box-sizing: border-box !important;word-wrap: break-word !important;\"><\/span><\/strong><\/span>\u7248<\/section>\n<\/section>\n<section style=\"max-width: 100%;border-radius: 100%;width: 2em;height: 2em;text-align: center;color: rgb(255, 255, 255);line-height: 2em;vertical-align: top;display: inline-block;background-color: rgb(170, 33, 94);box-sizing: border-box !important;word-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\">\u6743<\/section>\n<\/section>\n<section style=\"max-width: 100%;border-radius: 100%;width: 2em;height: 2em;text-align: center;color: rgb(255, 255, 255);line-height: 2em;vertical-align: top;display: inline-block;background-color: rgb(170, 33, 94);box-sizing: border-box !important;word-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\">\u58f0<\/section>\n<\/section>\n<section style=\"max-width: 100%;border-radius: 100%;width: 2em;height: 2em;text-align: center;color: rgb(255, 255, 255);line-height: 2em;vertical-align: top;display: inline-block;background-color: rgb(170, 33, 94);box-sizing: border-box !important;word-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\">\u660e<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;line-height: 25.6px;font-size: 14px;box-sizing: border-box !important;word-wrap: break-word !important;\">\u6b22\u8fce\u4e2a\u4eba\u8f6c\u53d1\u5206\u4eab\u3002\u5176\u4ed6\u4efb\u4f55\u5a92\u4f53\u3001\u7f51\u7ad9\u5982\u9700\u8f6c\u8f7d\u6216\u5f15\u7528\u672c\u7f51\u7248\u6743\u6240\u6709\u5185\u5bb9\u987b\u83b7\u5f97\u6388\u6743\u4e14\u5728\u9192\u76ee\u4f4d\u7f6e\u5904\u6ce8\u660e\u201c\u8f6c\u81ea\uff1a\u751f\u7269\u5236\u836f\u5c0f\u7f16\u201d\u3002<\/span><\/p>\n<section style=\"max-width: 100%;font-family: inherit;text-decoration: inherit;letter-spacing: 0.544px;border-color: rgb(249, 110, 87);box-sizing: border-box !important;word-wrap: break-word !important;\">\n<section style=\"max-width: 100%;height: 16px;text-align: center;font-size: 1em;box-sizing: border-box !important;word-wrap: break-word !important;\">\n<section style=\"max-width: 100%;border-color: rgb(249, 110, 87);width: 24px;height: 16px;border-top-width: 6px;border-top-style: solid;border-left-width: 6px;border-left-style: solid;float: left;box-sizing: border-box !important;word-wrap: break-word !important;\"><\/section>\n<section style=\"max-width: 100%;border-color: rgb(249, 110, 87);width: 24px;height: 16px;border-top-width: 6px;border-top-style: solid;border-right-width: 6px;border-right-style: solid;float: right;box-sizing: border-box !important;word-wrap: break-word !important;\"><\/section>\n<section style=\"max-width: 100%;color: transparent;clear: both;display: inline-block;box-sizing: border-box !important;word-wrap: break-word !important;\"><\/section>\n<\/section>\n<section style=\"margin: -13px 3px;padding: 12px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;border-radius: 6px;border-width: 1px;border-style: solid;border-color: rgb(249, 110, 87);line-height: 1.4;font-family: inherit;\">\n<section style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\">\n<p style=\"max-width: 100%;min-height: 1em;text-align: center;font-size: 1em;box-sizing: border-box !important;word-wrap: break-word !important;\"><img class=\"\"     width=\"auto\"  style=\"box-sizing: border-box !important;word-wrap: break-word !important;visibility: visible !important;width: auto !important;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/08\/beepress2-1533786862.jpeg\" alt=\"\u6bcf\u5468\u6297\u4f53\u836f\u8baf20180730-20180805\" title=\"\u6bcf\u5468\u6297\u4f53\u836f\u8baf20180730-20180805\"><br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 14px;box-sizing: border-box !important;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;color: rgb(0, 112, 192);font-family: inherit;font-size: 1em;line-height: 1.4;text-decoration: inherit;box-sizing: border-box !important;word-wrap: break-word !important;\">\u575a\u6301\u539f\u521b\u3001\u575a\u6301\u4e13\u4e1a<\/strong><\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;text-align: center;line-height: 19.6px;font-size: 1em;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 14px;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;color: rgb(0, 112, 192);line-height: 1.4;font-family: inherit;text-decoration: inherit;box-sizing: border-box !important;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\">\u6b22\u8fce\u5173\u6ce8<\/strong><\/span><span style=\"max-width: 100%;color: rgb(192, 0, 0);line-height: 1.4;font-family: inherit;text-decoration: inherit;box-sizing: border-box !important;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\">\u751f\u7269\u5236\u836f\u5c0f\u7f16<\/strong><\/span><\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;text-align: center;line-height: 19.6px;font-size: 1em;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;color: rgb(0, 0, 0);font-size: 14px;box-sizing: border-box !important;word-wrap: break-word !important;\">\u6295\u7a3f\u4fe1\u7bb1\uff1awuwj06@163.com<\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;text-align: center;line-height: 19.6px;font-size: 1em;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 14px;box-sizing: border-box !important;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;color: rgb(0, 112, 192);line-height: 19.6px;font-family: inherit;font-size: 1em;text-decoration: inherit;box-sizing: border-box !important;word-wrap: break-word !important;\">\u5c0f\u7f16\u56e2\u961f\u73b0\u670921\u4f4d\u6210\u5458\uff1a<\/strong><span style=\"max-width: 100%;color: rgb(0, 0, 0);box-sizing: border-box !important;word-wrap: break-word !important;\"><\/span><\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;text-align: center;line-height: 19.6px;font-size: 1em;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 14px;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;color: rgb(0, 0, 0);box-sizing: border-box !important;word-wrap: break-word !important;\">Armstrong\u3001\u533b\u836f\u5c40\u5916\u4eba\u3001Fairy\u3001<\/span><span style=\"max-width: 100%;color: rgb(0, 0, 0);line-height: 19.6px;font-family: inherit;text-decoration: inherit;box-sizing: border-box !important;word-wrap: break-word !important;\">Jone\u3001<\/span><span style=\"max-width: 100%;line-height: 19.6px;font-family: inherit;text-decoration: inherit;color: rgb(0, 0, 0);box-sizing: border-box !important;word-wrap: break-word !important;\">\u4e1c\u80dc\u897f\u725b\u3001Alpharesearcher\u3001MT\u3001\u767e\u8349\u3001Irene\u3001<\/span><span style=\"max-width: 100%;color: rgb(0, 0, 0);font-family: inherit;line-height: 19.6px;text-decoration: inherit;box-sizing: border-box !important;word-wrap: break-word !important;\">Self Renew\u3001\u86cb\u767d\u5de5\u4eba\u3001At.Zhou\u3001Julia\u3001\u6e38\u65b9\u548c\u5c1a\u3001Grand\u3001\u5915\u9633\u6b66\u58eb\u3001\u5403\u74dc\u7fa4\u4f17\u3001Nathan\u3001\u795e\u7ecf\u5143\u3001Clear\u516e\u3001\u5357\u5c71\u5357<\/span><\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;text-align: center;line-height: 19.6px;font-size: 1em;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;color: rgb(0, 0, 0);font-size: 14px;box-sizing: border-box !important;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;color: rgb(0, 112, 192);line-height: 19.6px;font-family: inherit;font-size: 1em;text-decoration: inherit;box-sizing: border-box !important;word-wrap: break-word !important;\">\u6b22\u8fce\u6709\u5171\u540c\u5174\u8da3\u7684\u670b\u53cb\u52a0\u5165<\/strong><\/span><\/p>\n<\/section>\n<\/section>\n<section style=\"max-width: 100%;height: 16px;font-size: 1em;box-sizing: border-box !important;word-wrap: break-word !important;\">\n<section style=\"max-width: 100%;border-color: rgb(249, 110, 87);width: 24px;height: 16px;border-bottom-width: 6px;border-bottom-style: solid;border-left-width: 6px;border-left-style: solid;float: left;box-sizing: border-box !important;word-wrap: break-word !important;\"><\/section>\n<section style=\"max-width: 100%;border-color: rgb(249, 110, 87);width: 24px;height: 16px;border-right-width: 6px;border-right-style: solid;border-bottom-width: 6px;border-bottom-style: solid;float: right;box-sizing: border-box !important;word-wrap: break-word !important;\"><\/section>\n<\/section>\n<\/section>\n<p><\/p>\n<blockquote class='keep-source'>\n<p>\u59cb\u53d1\u4e8e\u5fae\u4fe1\u516c\u4f17\u53f7\uff1a                         \u751f\u7269\u5236\u836f\u5c0f\u7f16                      <\/p>\n<\/blockquote>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>\u4f5c\u8005 l&nbsp;\u653e\u7fc1\u662f\u6c34\u8d27 \u7f16\u8f91&nbsp;l&nbsp;\u7ec6\u80de\u623f\u95f4 1 Kymab\u516c\u5e03\u4e86\u6cbb\u7597\u81ea\u8eab\u514d\u75ab\u6027\u75be\u75c5 [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":28226,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[2],"tags":[],"_links":{"self":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/28225"}],"collection":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/comments?post=28225"}],"version-history":[{"count":1,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/28225\/revisions"}],"predecessor-version":[{"id":28235,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/28225\/revisions\/28235"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/media\/28226"}],"wp:attachment":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/media?parent=28225"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/categories?post=28225"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/tags?post=28225"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}