{"id":29165,"date":"2018-08-08T01:00:00","date_gmt":"2018-08-09T03:59:34","guid":{"rendered":"http:\/\/www.05921.net\/index.php\/2018\/08\/09\/%e9%80%9f%e9%80%92-%e7%bc%93%e8%a7%a3%e7%8e%87%e8%be%be97%ef%bc%81%e8%a1%80%e5%8f%8b%e7%97%85%e5%9f%ba%e5%9b%a0%e7%96%97%e6%b3%95%e6%95%88%e6%9e%9c%e6%98%be%e8%91%97\/"},"modified":"2018-08-09T11:59:36","modified_gmt":"2018-08-09T03:59:36","slug":"%e9%80%9f%e9%80%92-%e7%bc%93%e8%a7%a3%e7%8e%87%e8%be%be97%ef%bc%81%e8%a1%80%e5%8f%8b%e7%97%85%e5%9f%ba%e5%9b%a0%e7%96%97%e6%b3%95%e6%95%88%e6%9e%9c%e6%98%be%e8%91%97","status":"publish","type":"post","link":"https:\/\/www.05921.net\/index.php\/29165\/","title":{"rendered":"\u901f\u9012 | \u7f13\u89e3\u7387\u8fbe97%\uff01\u8840\u53cb\u75c5\u57fa\u56e0\u7597\u6cd5\u6548\u679c\u663e\u8457"},"content":{"rendered":"
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\u258e\u836f\u660e<\/span><\/strong>\u5eb7\u5fb7\/\u62a5\u9053<\/span><\/strong><\/strong><\/span><\/strong><\/strong><\/span><\/strong><\/strong><\/strong><\/span><\/strong><\/strong><\/span><\/strong><\/strong><\/h1>\n

Spark Therapeutics\u4eca\u65e5\u5ba3\u5e03\uff0c12\u540d\u7532\u578b\u8840\u53cb\u75c5\u60a3\u8005\u5728\u63a5\u53d7\u57fa\u56e0\u7597\u6cd5SPK-8011\u6cbb\u7597\u540e\uff0c\u7f13\u89e3\u7387\u8fbe\u523097\uff05<\/strong>\u3002
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\u672c\u6587\u6765\u6e90\uff1a\u836f\u660e\u5eb7\u5fb7<\/span><\/p>\n

Spark\u7814\u53d1\u7684SPK-8011\u662f\u4e00\u79cd\u4f7f\u7528Spark200\u8863\u58f3\u4e14\u542b\u6709\u5bc6\u7801\u5b50\u4f18\u5316\u7684\u4eba\u6e90\u56e0\u5b50VIII\u57fa\u56e0\u7684\u65b0\u578b\u751f\u7269\u5de5\u7a0b\u817a\u76f8\u5173\u75c5\u6bd2\uff08AAV\uff09\u8f7d\u4f53<\/strong>\u3002\u5b83\u53ef\u4ee5\u66f4\u6709\u6548\u5730\u8f6c\u5bfc\u4eba\u809d\u7ec6\u80de\uff0c\u5e76\u8868\u8fbe\u5bc6\u7801\u5b50\u4f18\u5316\u7684B\u7ed3\u6784\u57df\u7f3a\u5931\u7684\u56e0\u5b50VIII\u57fa\u56e0\uff0c\u5185\u6e90\u6027\u4ea7\u751f\u56e0\u5b50VIII\uff0c\u7528\u4e8e\u6cbb\u7597\u7532\u578b\u8840\u53cb\u75c5\u3002<\/span><\/p>\n


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\u25b2Spark Therapeutics\u603b\u88c1\u517c\u7814\u53d1\u8d1f\u8d23\u4ebaKatherine High\u535a\u58eb\uff08\u56fe\u7247\u6765\u6e90\uff1aSpark Therapeutics\u5b98\u65b9\u7f51\u7ad9\uff09<\/span><\/strong><\/p>\n


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\u201cSPK-8011\u7684\u4e34\u5e8a\u6570\u636e\u548c\u5b89\u5168\u6027\u975e\u5e38\u4ee4\u4eba\u9f13\u821e\uff0c\u6ca1\u6709\u89c2\u5bdf\u5230\u51fa\u73b0\u56e0\u5b50VIII\u6291\u5236\u5242\u3002\u8f6c\u6c28\u9176\u5347\u9ad8\u8d85\u8fc7\u6b63\u5e38\u4e0a\u9650\u4ec5\u57283\u540d\u53c2\u4e0e\u8005\u4e2d\u89c2\u5bdf\u5230\uff0c\u6ca1\u6709\u8f6c\u6c28\u9176\u6301\u7eed\u5347\u9ad8\u7684\u8bc1\u636e\u3002\u6211\u4eec\u76f8\u4fe1\uff0c\u6839\u636e\u89c2\u5bdf\u5230\u7684\u514d\u75ab\u53cd\u5e94\u7684\u8282\u594f\u548c\u7a0b\u5ea6\uff0c\u9884\u9632\u6027\u7c7b\u56fa\u9187\u7597\u6cd5\u5c06\u6291\u5236\u8fd9\u4e9b\u53cd\u5e94\uff0c\u5e76\u4e14\u4f7f\u6240\u6709SPK-8011\u5242\u91cf\u4e3a2×10^12 vg\/kg\u7684\u53c2\u4e0e\u8005\u7684\u56e0\u5b50VIII\u957f\u671f\u8868\u8fbe\u8d85\u8fc712\uff05\u3002\u6211\u4eec\u8ba1\u5212\u5b9e\u65bd\u8fd9\u79cd\u9884\u9632\u6027\u7684\u7c7b\u56fa\u9187\u7ba1\u7406\u65b9\u6cd5\uff0c\u201cSpark\u603b\u88c1\u517c\u7814\u53d1\u8d1f\u8d23\u4ebaKatherine High\u535a\u58eb\u8bf4\uff1a\u201c\u8fd9\u4e9b\u65e9\u671f\u6570\u636e\u8fdb\u4e00\u6b65\u652f\u6301\u4e86\u56e0\u5b50\u6d3b\u6027\u6c34\u5e73\u8d85\u8fc712\uff05\u5bf9\u60a3\u8005\u9884\u540e\u9020\u6210\u7684\u5de8\u5927\u5f71\u54cd\uff0c\u4f7f\u6211\u4eec\u66f4\u63a5\u8fd1\u6d88\u9664\u81ea\u53d1\u6027\u51fa\u8840\u7684\u76ee\u6807\uff0c\u4f7f\u7532\u578b\u8840\u53cb\u75c5\u60a3\u8005\u4e0d\u518d\u9700\u8981\u5b9a\u671f\u8f93\u6ce8\u3002\u201d<\/span><\/p>\n


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\u57fa\u4e8e\u5230\u76ee\u524d\u4e3a\u6b62\u7684\u603b\u4f53\u7ed3\u679c\uff0cSpark\u6253\u7b97\u5728\u4eca\u5e74\u7b2c\u56db\u5b63\u5ea6\u542f\u52a83\u671f\u8bd5\u8fd0\u884c\u7814\u7a76\u3002\u5728\u8bd5\u8fd0\u884c\u7814\u7a76\u5b8c\u6210\u540e\uff0c3\u671f\u53c2\u4e0e\u8005\u5c06\u63a5\u53d72×10^12 vg\/kg\u7684SPK-8011\u3002<\/span><\/p>\n


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\u6211\u4eec\u671f\u5f85\u8fd9\u6b3e\u57fa\u56e0\u7597\u6cd5\u80fd\u4e3a\u7532\u578b\u8840\u53cb\u75c5\u60a3\u8005\u5e26\u6765\u957f\u4e45\u7684\u75be\u75c5\u7f13\u89e3\u3002<\/span><\/p>\n


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\u53c2\u8003\u8d44\u6599\uff1a<\/span><\/p>\n

[1] Spark’s Hemophilia A Gene Therapy Significantly Reduced Bleeding in Clinical Trial. Retrieved August 7, 2018, from https:\/\/www.biospace.com\/article\/spark-s-hemophilia-a-gene-therapy-significantly-reduced-bleeding-in-clinical-trial\/<\/span><\/p>\n

[2] Spark Therapeutics. Retrieved August 7, 2018, from http:\/\/ir.sparktx.com\/news-releases\/news-release-details\/spark-therapeutics-reports-second-quarter-2018-financial-results<\/span>
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[3] \u8840\u53cb\u75c5\u57fa\u56e0\u7597\u6cd5\u4e34\u5e8a\u8bd5\u9a8c\u73b0\u66d9\u5149. Retrieved August 7, 2018, from \u836f\u660e\u5eb7\u5fb7\u5fae\u4fe1\u516c\u4f17\u53f7\uff08WuXiAppTecChina\uff09<\/span><\/h2>\n


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\u672c\u6587\u6765\u81ea\u836f\u660e\u5eb7\u5fb7\u5fae\u4fe1\u56e2\u961f\uff0c\u6b22\u8fce\u8f6c\u53d1\u5230\u670b\u53cb\u5708\uff0c\u8c22\u7edd\u8f6c\u8f7d\u5230\u5176\u4ed6\u5e73\u53f0\uff1b\u5982\u6709\u5f00\u8bbe\u767d\u540d\u5355\u9700\u6c42\uff0c\u8bf7\u5728\u6587\u7ae0\u5e95\u90e8\u7559\u8a00\uff1b\u5982\u6709\u5176\u4ed6\u5408\u4f5c\u9700\u6c42\uff0c\u8bf7\u8054\u7cfbwuxi_media@wuxiapptec.com<\/span><\/p>\n


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\"\u901f\u9012<\/p>\n

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\u59cb\u53d1\u4e8e\u5fae\u4fe1\u516c\u4f17\u53f7\uff1a \u836f\u660e\u5eb7\u5fb7 <\/p>\n<\/blockquote>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

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