{"id":29405,"date":"2018-08-03T01:00:00","date_gmt":"2018-08-09T04:01:17","guid":{"rendered":"http:\/\/www.05921.net\/index.php\/2018\/08\/09\/fda%e5%b1%80%e9%95%bf%e6%9c%80%e6%96%b0%e8%ae%b2%e8%af%9d%ef%bc%9a%e4%b8%b4%e5%ba%8a%e8%af%95%e9%aa%8c%e6%94%b9%e9%9d%a9%e5%8a%bf%e5%9c%a8%e5%bf%85%e8%a1%8c%ef%bc%81\/"},"modified":"2018-08-09T12:01:21","modified_gmt":"2018-08-09T04:01:21","slug":"fda%e5%b1%80%e9%95%bf%e6%9c%80%e6%96%b0%e8%ae%b2%e8%af%9d%ef%bc%9a%e4%b8%b4%e5%ba%8a%e8%af%95%e9%aa%8c%e6%94%b9%e9%9d%a9%e5%8a%bf%e5%9c%a8%e5%bf%85%e8%a1%8c%ef%bc%81","status":"publish","type":"post","link":"https:\/\/www.05921.net\/index.php\/29405\/","title":{"rendered":"FDA\u5c40\u957f\u6700\u65b0\u8bb2\u8bdd\uff1a\u4e34\u5e8a\u8bd5\u9a8c\u6539\u9769\u52bf\u5728\u5fc5\u884c\uff01"},"content":{"rendered":"<div class=\"bpp-post-content\">\n<h1 style=\"margin-bottom: 0.8em;font-weight: inherit;font-size: 1.7em;max-width: 100%;box-sizing: border-box;word-wrap: break-word;color: rgb(51, 51, 51);\"><strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;line-height: 32px;font-size: 20px;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-family: SimSun;box-sizing: border-box !important;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;line-height: 32px;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;line-height: 32px;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;line-height: 32px;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;line-height: 1.75em;font-family: \u5fae\u8f6f\u96c5\u9ed1, sans-serif;font-size: 15px;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;color: rgb(0, 112, 192);font-family: \u6977\u4f53;box-sizing: border-box !important;word-wrap: break-word !important;\">\u258e\u836f\u660e<\/span><\/strong><strong style=\"max-width: 100%;line-height: 1.75em;font-family: \u5fae\u8f6f\u96c5\u9ed1, sans-serif;font-size: 15px;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;color: rgb(0, 112, 192);font-family: \u6977\u4f53;box-sizing: border-box !important;word-wrap: break-word !important;\">\u5eb7\u5fb7\/\u62a5\u9053<\/span><\/strong><\/strong><\/span><\/strong><\/strong><\/span><\/strong><\/strong><\/strong><\/span><\/strong><\/strong><\/span><\/strong><\/strong><\/h1>\n<p style=\"line-height: 1.75em;\"><span style=\"font-size: 15px;\">\u8fd1\u65e5\uff0c\u7f8e\u56fdFDA\u5c40\u957fScott Gottlieb\u535a\u58eb\u5728\u4e00\u6b21\u53e3\u5934\u62a5\u544a\u4e2d\uff0c\u4ecb\u7ecd\u4e86FDA\u5728\u843d\u5b9e\u300a21\u4e16\u7eaa\u6cbb\u6108\u6cd5\u6848\u300b\u4e2d\u6240\u53d6\u5f97\u7684\u8fdb\u5c55\u3002<strong>\u5176\u4e2d\uff0cGottlieb\u535a\u58eb\u6307\u51fa\uff0c\u76ee\u524d\u5728\u4e34\u5e8a\u8bd5\u9a8c\u4e0a\u7684\u9650\u5236\uff0c\u5f71\u54cd\u4e86\u65b0\u836f\u83b7\u6279\u4e0a\u5e02\u3001\u6765\u5230\u60a3\u8005\u9762\u524d\u7684\u901f\u5ea6\u3002<\/strong>\u4e3a\u6b64\uff0cFDA\u4e5f\u5c06\u7ee7\u7eed\u5bf9\u4e34\u5e8a\u8bd5\u9a8c\u8fdb\u884c\u6539\u9769\uff0c\u8ba9\u66f4\u591a\u60a3\u8005\u66f4\u5feb\u7528\u4e0a\u5b89\u5168\u6709\u6548\u7684\u521b\u65b0\u7597\u6cd5\u3002<\/span><\/p>\n<p style=\"line-height: 1.75em;\"><span style=\"font-size: 15px;\"><br  \/><\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);text-align: center;\"><img class=\"\"       style=\"box-sizing: border-box !important;word-wrap: break-word !important;width: 393px !important;visibility: visible !important;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/08\/beepress10-1533787278.jpeg\" alt=\"FDA\u5c40\u957f\u6700\u65b0\u8bb2\u8bdd\uff1a\u4e34\u5e8a\u8bd5\u9a8c\u6539\u9769\u52bf\u5728\u5fc5\u884c\uff01\" title=\"FDA\u5c40\u957f\u6700\u65b0\u8bb2\u8bdd\uff1a\u4e34\u5e8a\u8bd5\u9a8c\u6539\u9769\u52bf\u5728\u5fc5\u884c\uff01\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);text-align: center;\"><strong style=\"max-width: 100%;color: rgb(62, 62, 62);font-size: 18px;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 14px;color: rgb(0, 112, 192);box-sizing: border-box !important;word-wrap: break-word !important;\">\u25b2FDA\u5c40\u957f<\/span><\/strong><strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 14px;color: rgb(0, 112, 192);box-sizing: border-box !important;word-wrap: break-word !important;\">Scott Gottlieb\u535a\u58eb\u8fd1\u65e5\u53d1\u8868\u4e86\u5173\u4e8e\u4e34\u5e8a\u8bd5\u9a8c\u6539\u9769\u7684\u8bb2\u8bdd<\/span><\/strong><strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 14px;color: rgb(0, 112, 192);box-sizing: border-box !important;word-wrap: break-word !important;\">\uff08\u56fe\u7247\u6765\u6e90\uff1aFDA\u5b98\u7f51\uff09<\/span><\/strong><\/p>\n<p><br  \/><\/p>\n<section style=\"max-width: 100%;box-sizing: border-box;color: rgb(51, 51, 51);\">\n<section class=\"\"  style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<section class=\"\" style=\"margin-top: 10px;max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<section class=\"\" style=\"padding-left: 5px;max-width: 100%;box-sizing: border-box;display: inline-block;width: 638.4px;border-width: 0px 0px 0px 10px;border-style: solid;border-left-color: rgb(0, 112, 192);border-right-color: rgb(0, 112, 192);word-wrap: break-word !important;\">\n<section class=\"\"  style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;color: rgb(0, 112, 192);word-wrap: break-word !important;\">\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 15px;box-sizing: border-box !important;word-wrap: break-word !important;\">Second-in-class\u5728\u54ea\u91cc\uff1f<\/span><\/strong><\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"\"  style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<section class=\"\" style=\"margin-bottom: 8px;max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;background-color: rgb(0, 112, 192);height: 1px;word-wrap: break-word !important;\"><\/section>\n<\/section>\n<\/section>\n<\/section>\n<p style=\"line-height: 1.75em;\"><br  \/><\/p>\n<p style=\"line-height: 1.75em;\"><strong><span style=\"font-size: 15px;\">\u65b0\u836f\u4ece\u7814\u53d1\u5230\u4e0a\u5e02\u662f\u4e00\u6761\u6f2b\u957f\u7684\u9053\u8def\uff0c\u5176\u4e2d\u5f88\u957f\u7684\u4e00\u6bb5\u65c5\u7a0b\u662f\u4e34\u5e8a\u8bd5\u9a8c\u3002<\/span><\/strong><span style=\"font-size: 15px;\">\u4e3a\u4e86\u786e\u8ba4\u65b0\u836f\u5206\u5b50\u7684\u5b89\u5168\u6027\u4e0e\u6709\u6548\u6027\uff0c\u4e34\u5e8a\u8bd5\u9a8c\u662f\u4e0d\u53ef\u6216\u7f3a\u7684\u3002\u4f46\u4e34\u5e8a\u8bd5\u9a8c\u7684\u6210\u672c\u4e0e\u590d\u6742\u5ea6\uff0c\u4e5f\u53ef\u80fd\u4e3a\u65b0\u836f\u4e0a\u5e02\u5e26\u6765\u963b\u788d\uff0c\u5ef6\u957f\u65b0\u836f\u7814\u53d1\u7684\u5468\u671f\u3002<\/span><\/p>\n<p><br  \/><\/p>\n<p style=\"line-height: 1.75em;\"><span style=\"font-size: 15px;\">\u8fd9\u6b63\u662fFDA\u4e3b\u5bfc\u7684\u4e00\u9879\u7814\u7a76\u6240\u53d1\u73b0\u7684\u7ed3\u679c\u3002\u5728\u8be5\u7814\u7a76\u4e2d\uff0c\u4eba\u4eec\u5206\u6790\u4e86\u7531CDER\u6279\u51c6\u7684\u540c\u7c7b\u7597\u6cd5\u7684\u6570\u76ee\u3002\u540c\u7c7b\u7597\u6cd5\u662f\u6307\u5177\u6709\u540c\u6837\u4f5c\u7528\u673a\u5236\uff0c\u5bf9\u76f8\u540c\u6216\u76f8\u5173\u75be\u75c5\u8fdb\u884c\u6cbb\u7597\u7684\u7597\u6cd5\u3002<strong>\u5206\u6790\u7ed3\u679c\u5219\u8868\u660e\uff0c\u8fd1\u5e74\u6765\uff0c\u540c\u7c7b\u7597\u6cd5\u7684\u4e0a\u5e02\u901f\u5ea6\u6709\u7740\u660e\u663e\u7684\u653e\u7f13\u3002<\/strong><\/span><\/p>\n<p><span style=\"color: rgb(255, 255, 255);font-size: 15px;\">\u672c\u6587\u6765\u6e90\uff1a\u836f\u660e\u5eb7\u5fb7<\/span><\/p>\n<p style=\"line-height: 1.75em;\"><span style=\"font-size: 15px;\">\u5bf9\u4e8e\u975e\u5b64\u513f\u836f\uff08\u6cbb\u7597\u5e7f\u5927\u7684\u60a3\u8005\u7fa4\u4f53\uff09\u6765\u8bf4\uff0c\u57281991\u5e74\u52302000\u5e74\u8fd910\u5e74\u91cc\u83b7\u6279\u7684\u201cfirst-in-class\u201d\u65b0\u836f\u4e2d\uff0c\u670941%\u7684\u65b0\u836f\u5728\u77ed\u77ed5\u5e74\u91cc\uff0c\u5c31\u8fce\u6765\u4e86\u201csecond-in-class\u201d\u7684\u540c\u7c7b\u836f\u7269\uff0c\u8fd9\u4e5f\u8ba9\u60a3\u8005\u4eec\u8fce\u6765\u4e86\u66f4\u591a\u7684\u6cbb\u7597\u9009\u62e9\u3002<strong>\u7136\u800c\u57282001\u5e74\u52302010\u5e74\u8fd910\u5e74\u91cc\uff0c\u8fd9\u4e00\u6bd4\u4f8b\u6709\u7740\u660e\u663e\u4e0b\u964d\u2014\u2014\u53ea\u670918%\u7684\u201cfirst-in-class\u201d\u65b0\u836f\u57285\u5e74\u91cc\u8fce\u6765\u4e86\u540c\u7c7b\u7597\u6cd5\u3002<\/strong><\/span><\/p>\n<p style=\"line-height: 1.75em;\"><span style=\"font-size: 15px;\"><strong><br  \/><\/strong><\/span><\/p>\n<p style=\"text-align: center;\"><img class=\"\"       style=\"\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/08\/beepress10-1533787278.jpg\" alt=\"FDA\u5c40\u957f\u6700\u65b0\u8bb2\u8bdd\uff1a\u4e34\u5e8a\u8bd5\u9a8c\u6539\u9769\u52bf\u5728\u5fc5\u884c\uff01\" title=\"FDA\u5c40\u957f\u6700\u65b0\u8bb2\u8bdd\uff1a\u4e34\u5e8a\u8bd5\u9a8c\u6539\u9769\u52bf\u5728\u5fc5\u884c\uff01\"  \/><\/p>\n<p style=\"text-align: center;\"><br  \/><\/p>\n<p><span style=\"font-size: 15px;\">\u4ece\u53e6\u4e00\u4e2a\u7ef4\u5ea6\u770b\uff0c\u57281991\u5e74\u52302000\u5e74\u671f\u95f4\uff0c\u4ec5\u4ec5\u9700\u89812\u5e74\uff0c\u5c31\u6709\u56db\u5206\u4e4b\u4e00\u7684\u201cfirst-in-class\u201d\u65b0\u836f\u8fce\u6765\u4e86\u540c\u7c7b\u7597\u6cd5\u3002\u800c\u57282001\u5e74\u52302010\u5e74\u671f\u95f4\uff0c\u60a3\u8005\u9700\u8981\u7b49\u5f85\u7684\u65f6\u95f4\u8981\u8d85\u8fc77\u5e74\u3002<\/span><br  \/><\/p>\n<p><br  \/><\/p>\n<p style=\"line-height: 1.75em;\"><span style=\"font-size: 15px;\">\u5728\u5b64\u513f\u836f\u9886\u57df\uff0c\u8fd9\u4e2a\u73b0\u8c61\u540c\u6837\u5b58\u5728\u3002\u4e0e1991\u5e74\u52302000\u5e74\u671f\u95f4\u76f8\u6bd4\uff0c\u57282001\u5e74\u52302010\u5e74\u671f\u95f4\uff0c\u53ea\u670913%\u7684\u201cfirst-in-class\u201d\u5b64\u513f\u836f\u80fd\u591f\u57285\u5e74\u91cc\u8fce\u6765\u53e6\u4e00\u6b3e\u540c\u7c7b\u7597\u6cd5\uff0c\u5e45\u5ea6\u4ec5\u4e3a\u4e4b\u524d\u768450%\u3002<\/span><\/p>\n<p><span style=\"color: rgb(255, 255, 255);font-size: 15px;\">\u672c\u6587\u6765\u6e90\uff1a\u836f\u660e\u5eb7\u5fb7<\/span><\/p>\n<p style=\"line-height: 1.75em;\"><span style=\"font-size: 15px;\">\u201c<strong>\u73b0\u6709\u2018\u4e00\u6b3e\u65b0\u836f\uff0c\u4e00\u9879\u4e34\u5e8a\u8bd5\u9a8c\u2019\u7684\u6548\u7387\u4e0d\u9ad8\uff0c\u53ef\u80fd\u5e26\u6765\uff08\u8d44\u6e90\u7684\uff09\u6d6a\u8d39<\/strong>\uff0c\u201d Gottlieb\u535a\u58eb\u8bf4\u9053\uff1a\u201c\u5b83\u4e0d\u4f46\u4f1a\u5ef6\u8bef\u521b\u65b0\u7597\u6cd5\u7684\u4e0a\u5e02\uff0c\u8fd8\u4f1a\u5ef6\u7f13\u5bf9\u8fd9\u4e9b\u7597\u6cd5\u8868\u73b0\u7684\u5145\u5206\u8bc4\u4f30\u3002\u201d<\/span><\/p>\n<p><br  \/><\/p>\n<section style=\"white-space: normal;max-width: 100%;box-sizing: border-box;color: rgb(51, 51, 51);\">\n<section class=\"\"  style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<section class=\"\" style=\"margin-top: 10px;max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<section class=\"\" style=\"padding-left: 5px;max-width: 100%;box-sizing: border-box;display: inline-block;width: 638.4px;border-width: 0px 0px 0px 10px;border-style: solid;border-left-color: rgb(0, 112, 192);border-right-color: rgb(0, 112, 192);word-wrap: break-word !important;\">\n<section class=\"\"  style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;color: rgb(0, 112, 192);word-wrap: break-word !important;\">\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 15px;box-sizing: border-box !important;word-wrap: break-word !important;\">\u4e34\u5e8a\u8bd5\u9a8c\u6539\u9769<\/span><\/strong><\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"\"  style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<section class=\"\" style=\"margin-bottom: 8px;max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;background-color: rgb(0, 112, 192);height: 1px;word-wrap: break-word !important;\"><\/section>\n<\/section>\n<\/section>\n<\/section>\n<p><br  \/><\/p>\n<p style=\"line-height: 1.75em;\"><span style=\"font-size: 15px;\">Gottlieb\u535a\u58eb\u5728\u62a5\u544a\u4e2d\u6307\u51fa\uff0c\u540c\u7c7b\u7597\u6cd5\u4e4b\u6240\u4ee5\u4e0a\u5e02\u7f13\u6162\uff0c\u90e8\u5206\u539f\u56e0\u5728\u4e8e\u5176\u4e34\u5e8a\u8bd5\u9a8c\u8bbe\u8ba1\u7684\u56f0\u96be\u3002<strong>\u5bf9\u4e8e\u90a3\u4e9b\u6709\u672a\u7adf\u6cbb\u7597\u9700\u6c42\u7684\u75be\u75c5\uff0c\u4e00\u65e6\u6709\u7597\u6cd5\u95ee\u4e16\uff0c\u7b2c\u4e8c\u6b3e\u7597\u6cd5\u7684\u4e0a\u5e02\u5c31\u4f1a\u53d8\u5f97\u56f0\u96be\u3002<\/strong>\u201c\u8fd9\u662f\u4e00\u4e2a\u95ee\u9898\u201d\uff0cGottlieb\u535a\u58eb\u8bf4\u3002\u800c\u89e3\u51b3\u4e4b\u9053\uff0c\u6216\u8bb8\u5c31\u662f\u5bf9\u4e34\u5e8a\u8bd5\u9a8c\u8fdb\u884c\u201c\u73b0\u4ee3\u5316\u6539\u9769\u201d\u3002<\/span><\/p>\n<p><br  \/><\/p>\n<p style=\"line-height: 1.75em;\"><span style=\"font-size: 15px;\">\u201c\u9ad8\u6548\u800c\u73b0\u4ee3\u7684\u4e34\u5e8a\u8bd5\u9a8c\u8bbe\u8ba1\u4e0e\u8fdb\u884c\uff0c\u80fd\u89e3\u51b3\u90e8\u5206\u6311\u6218\uff0c\u201d Gottlieb\u535a\u58eb\u8865\u5145\u9053\uff1a\u201c\u8fd9\u4e9b\u65b9\u6cd5\u80fd\u8ba9\u6211\u4eec\u9ad8\u6548\u4e86\u89e3\u66f4\u591a\u65b0\u836f\u7684\u5b89\u5168\u6027\u4e0e\u6536\u76ca\u3002\u5982\u679c\u4f60\u6240\u505a\u7684\u662f\u73b0\u4ee3\u3001\u5faa\u8bc1\u3001\u4e25\u683c\u7684\u4e8b\uff0c\u5c31\u80fd\u786e\u4fdd\u6781\u5927\u7684\u9ad8\u6548\uff0c\u5e76\u5bf9FDA\u91d1\u6807\u51c6\u5e26\u6765\u6781\u5927\u4fdd\u969c\u3002\u201d<\/span><\/p>\n<p style=\"line-height: 1.75em;\"><span style=\"font-size: 15px;\"><br  \/><\/span><\/p>\n<p style=\"text-align: center;\"><img class=\"\"       style=\"\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/08\/beepress3-1533787279.jpg\" alt=\"FDA\u5c40\u957f\u6700\u65b0\u8bb2\u8bdd\uff1a\u4e34\u5e8a\u8bd5\u9a8c\u6539\u9769\u52bf\u5728\u5fc5\u884c\uff01\" title=\"FDA\u5c40\u957f\u6700\u65b0\u8bb2\u8bdd\uff1a\u4e34\u5e8a\u8bd5\u9a8c\u6539\u9769\u52bf\u5728\u5fc5\u884c\uff01\"  \/><\/p>\n<p style=\"line-height: 1.75em;\"><span style=\"font-size: 15px;\"><\/span><\/p>\n<p style=\"white-space: normal;text-align: center;line-height: 1.75em;\"><strong><span style=\"font-size: 14px;color: rgb(0, 112, 192);\">\u25b2\u96e8\u4f1e\u8bd5\u9a8c\u4e0e\u7bee\u5b50\u8bd5\u9a8c\u793a\u610f\u56fe\uff08\u56fe\u7247\u6765\u6e90\uff1a\u300aJAMA Oncology\u300b\uff09<\/span><\/strong><\/p>\n<p><br  \/><\/p>\n<p style=\"line-height: 1.75em;\"><strong><span style=\"font-size: 15px;\">FDA\u62df\u542f\u52a8\u7684\u7b2c\u4e00\u9879\u4e3e\u63aa\uff0c\u662f\u540d\u4e3a\u201cMaster Clinical Trial Protocols\u201d\u7684\u65b9\u6cd5\uff0c\u5b83\u56ca\u62ec\u4e86\u7bee\u5b50\u8bd5\u9a8c\u3001\u96e8\u4f1e\u8bd5\u9a8c\u3001\u4ee5\u53ca\u5e73\u53f0\u8bd5\u9a8c\u3002<\/span><\/strong><span style=\"font-size: 15px;\">Gottlieb\u535a\u58eb\u8ba4\u4e3a\u201c\u8fd9\u4e9b\u65b9\u6cd5\u80fd\u6781\u5927\u63d0\u9ad8\u4e34\u5e8a\u8bd5\u9a8c\u7684\u6548\u7387\uff0c\u5e76\u964d\u4f4e\u6210\u672c\u201d\u3002\u5b83\u4eec\u6709\u671b\u6253\u7834\u201c\u4e00\u6b3e\u65b0\u836f\uff0c\u4e00\u9879\u4e34\u5e8a\u8bd5\u9a8c\u201d\u7684\u5e38\u89c4\uff0c\u901a\u8fc7\u5bf9\u4e34\u5e8a\u8bd5\u9a8c\u6846\u67b6\u7684\u666e\u53ca\uff0c\u57fa\u4e8e\u751f\u7269\u6807\u5fd7\u7269\uff0c\u5728\u4e00\u7c7b\u6216\u591a\u7c7b\u75be\u75c5\u4e2d\u6d4b\u8bd5\u591a\u79cd\u65b0\u836f\u3002\u8fc7\u53bb\uff0c\u6b64\u7c7b\u65b9\u6cd5\u5728\u80bf\u7624\u5b66\u9886\u57df\u5f97\u5230\u4e86\u521d\u6b65\u7684\u5c1d\u8bd5\u4e0e\u5e94\u7528\u3002\u5982\u4eca\uff0c\u5b83\u4eec\u6709\u671b\u5728\u66f4\u591a\u75be\u75c5\u9886\u57df\u4e2d\u5f97\u5230\u5e94\u7528\u3002<\/span><\/p>\n<p><br  \/><\/p>\n<p style=\"line-height: 1.75em;\"><strong><span style=\"font-size: 15px;\">\u800c\u53e6\u4e00\u9879\u4e3e\u63aa\u5219\u662f\u65e0\u7f1d\u7684\u4e34\u5e8a\u8bbe\u8ba1\uff0c\u5b83\u80fd\u5c06\u4f20\u7edf\u7684\u4e09\u5927\u4e34\u5e8a\u9636\u6bb5\u8fdb\u884c\u538b\u7f29\uff0c\u5408\u5e76\u6210\u4e00\u4e2a\u8fde\u7eed\u7684\u4e34\u5e8a\u8bd5\u9a8c\u3002<\/span><\/strong><span style=\"font-size: 15px;\">\u8fd9\u6709\u671b\u8ba9\u7814\u7a76\u4eba\u5458\u5728\u62db\u52df\u65b0\u7684\u60a3\u8005\u65f6\uff0c\u901a\u8fc7\u5df2\u77e5\u4fe1\u606f\u9884\u6d4b\u60a3\u8005\u7684\u7597\u6548\uff0c\u5c06\u4ed6\u4eec\u5206\u914d\u5230\u76f8\u5e94\u7684\u961f\u5217\u4e2d\u3002\u7531\u4e8e\u4e34\u5e8a\u8bd5\u9a8c\u7684\u4e3b\u8981\u65f6\u95f4\u6210\u672c\u4e0e\u91d1\u94b1\u6210\u672c\u4e3b\u8981\u8017\u8d39\u5728\u6bcf\u4e2a\u4e34\u5e8a\u8bd5\u9a8c\u9636\u6bb5\u7684\u7ed3\u675f\u4e0e\u5f00\u542f\u4e4b\u95f4\uff0c\u65b0\u7684\u201c\u8fde\u7eed\u4e34\u5e8a\u8bd5\u9a8c\u201d\u6846\u67b6\u6709\u671b\u964d\u4f4e\u6210\u672c\uff0c\u63d0\u9ad8\u6548\u7387\u3002<\/span><\/p>\n<p><br  \/><\/p>\n<section style=\"white-space: normal;max-width: 100%;box-sizing: border-box;color: rgb(51, 51, 51);\">\n<section class=\"\"  style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<section class=\"\" style=\"margin-top: 10px;max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<section class=\"\" style=\"padding-left: 5px;max-width: 100%;box-sizing: border-box;display: inline-block;width: 638.4px;border-width: 0px 0px 0px 10px;border-style: solid;border-left-color: rgb(0, 112, 192);border-right-color: rgb(0, 112, 192);word-wrap: break-word !important;\">\n<section class=\"\"  style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;color: rgb(0, 112, 192);word-wrap: break-word !important;\">\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 15px;box-sizing: border-box !important;word-wrap: break-word !important;\">\u65b0\u578b\u6307\u5bfc\u65b9\u9488<\/span><\/strong><\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"\"  style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<section class=\"\" style=\"margin-bottom: 8px;max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;background-color: rgb(0, 112, 192);height: 1px;word-wrap: break-word !important;\"><\/section>\n<\/section>\n<\/section>\n<\/section>\n<p><br  \/><\/p>\n<p style=\"line-height: 1.75em;\"><span style=\"font-size: 15px;\">\u4e3a\u4e86\u8ba9\u7814\u53d1\u65b0\u836f\u7684\u516c\u53f8\u66f4\u597d\u5730\u7406\u89e3\u8fd9\u4e9b\u65b0\u7b56\u7565\uff0c<strong>\u7f8e\u56fdFDA\u5373\u5c06\u516c\u5e03\u4e00\u7cfb\u5217\u6307\u5357<\/strong>\uff0c\u4ecb\u7ecd\u5982\u4f55\u5f00\u5c55\u65e0\u7f1d\u7684\u4e34\u5e8a\u8bd5\u9a8c\uff0c\u5982\u4f55\u968f\u7740\u8bd5\u9a8c\u8fdb\u5c55\u62d3\u5c55\u961f\u5217\uff0c\u4ee5\u53ca\u62d3\u5c55\u8fd9\u4e9b\u961f\u5217\u7684\u4e34\u5e8a\u6807\u51c6\u3002<\/span><\/p>\n<p><span style=\"color: rgb(255, 255, 255);font-size: 15px;\">\u672c\u6587\u6765\u6e90\uff1a\u836f\u660e\u5eb7\u5fb7<\/span><\/p>\n<p style=\"line-height: 1.75em;\"><span style=\"font-size: 15px;\">\u5177\u4f53\u6765\u8bf4\uff0c\u65b0\u7684\u6307\u5357\u5c06\u5bf9first-in-human\u7684\u4e34\u5e8a\u8bd5\u9a8c\u8fdb\u884c\u6307\u5bfc\uff0c\u534f\u52a9\u5f00\u8bbe\u591a\u4e2a\u53ef\u62d3\u5c55\u7684\u961f\u5217\uff0c\u52a0\u901f\u65b0\u836f\u4e34\u5e8a\u8bd5\u9a8c\u7684\u8fdb\u7a0b\u3002\u8fd9\u4e9b\u4e34\u5e8a\u8bd5\u9a8c\u9700\u8981\u901a\u8fc7\u751f\u7269\u6807\u5fd7\u7269\u5bf9\u60a3\u8005\u8fdb\u884c\u9009\u62e9\uff0c\u5e76\u80fd\u57fa\u4e8e\u79d1\u5b66\u65b9\u6cd5\uff0c\u544a\u8bc9\u6211\u4eec\u54ea\u4e9b\u4e2d\u671f\u4e34\u5e8a\u7ec8\u70b9\u6216\u66ff\u4ee3\u7ec8\u70b9\u53ef\u80fd\u4e0e\u957f\u671f\u4e34\u5e8a\u6548\u679c\u6709\u5173\uff0c\u4ece\u800c\u66f4\u4e3a\u4fbf\u6377\u5730\u627e\u5230\u836f\u7269\u7684\u79ef\u6781\u4f5c\u7528\u3002<\/span><\/p>\n<p style=\"line-height: 1.75em;\"><span style=\"font-size: 15px;\"><br  \/><\/span><\/p>\n<p style=\"line-height: 1.75em;\"><strong><span style=\"font-size: 15px;\">Gottlieb\u535a\u58eb\u8ba4\u4e3a\uff0c\u901a\u8fc7\u5e94\u7528\u8fd9\u4e9b\u65b9\u6cd5\uff0c\u6bcf\u4e00\u4e2a\u961f\u5217\u90fd\u80fd\u7528\u6765\u56de\u7b54\u5173\u4e8e\u65b0\u836f\u5b89\u5168\u6027\u4e0e\u7597\u6548\u7684\u7279\u5b9a\u95ee\u9898\u3002\u603b\u4f53\u770b\u6765\uff0c\u6211\u4eec\u4f1a\u63d0\u51fa\u66f4\u591a\u7684\u95ee\u9898\uff0c\u4e5f\u4f1a\u6536\u83b7\u66f4\u591a\u7684\u7b54\u6848\u3002<\/span><\/strong><\/p>\n<p style=\"line-height: 1.75em;\"><span style=\"font-size: 15px;\"><br  \/><\/span><\/p>\n<p style=\"line-height: 1.75em;\"><span style=\"font-size: 15px;\">\u800c\u5bf9\u4e8e\u90a3\u4e9b\u5df2\u7ecf\u83b7\u5f97\u7a81\u7834\u6027\u7597\u6cd5\u8ba4\u5b9a\u7684\u65b0\u836f\u6765\u8bf4\uff0c\u5bf9\u4e8e\u4e34\u5e8a\u8bd5\u9a8c\u961f\u5217\u7684\u6269\u589e\uff0c\u5219\u80fd\u901a\u8fc7\u7b5b\u90091\u671f\u4e34\u5e8a\u8bd5\u9a8c\u9636\u6bb5\u53d1\u73b0\u7684\u751f\u7269\u6807\u5fd7\u7269\uff0c\u6269\u5927\u62db\u52df\u7684\u8303\u56f4\uff0c\u4ee5\u5728\u65e0\u7f1d\u3001\u8fde\u7eed\u7684\u4e34\u5e8a\u8bd5\u9a8c\u4e2d\u5bf9\u65b0\u836f\u5c55\u5f00\u8bc4\u4f30\u3002<\/span><\/p>\n<p style=\"line-height: 1.75em;\"><span style=\"font-size: 15px;\"><br  \/><\/span><\/p>\n<p style=\"line-height: 1.75em;\"><span style=\"font-size: 15px;\">\u540c\u65f6\u8fdb\u5c55\u7684\u591a\u4e2a\u72ec\u7acb\u961f\u5217\uff0c\u80fd\u8ba9\u6211\u4eec\u5728\u5355\u9879\u5927\u578b\u4e34\u5e8a\u8bd5\u9a8c\u4e2d\u83b7\u5f97\u5927\u91cf\u6709\u7528\u7684\u4fe1\u606f\uff0c\u4e86\u89e3\u65b0\u836f\u7684\u5b89\u5168\u6027\u3001\u65b0\u836f\u5728\u4eba\u4f53\u5185\u5438\u6536\u4e0e\u5206\u5e03\u6709\u5173\u7684\u836f\u4ee3\u52a8\u529b\u5b66\u3001\u4ee5\u53ca\u65b0\u836f\u7684\u6297\u80bf\u7624\u6d3b\u6027\u3002\u53ea\u8981\u4e3a\u8fd9\u4e9b\u4e0d\u540c\u7684\u91cd\u8981\u95ee\u9898\u8bbe\u7acb\u5355\u72ec\u7684\u961f\u5217\uff0c\u5b83\u4eec\u5c31\u6709\u671b\u5f97\u5230\u8bc4\u4f30\u4e0e\u89e3\u7b54\u3002<strong>\u201c\u901a\u8fc7\u65e0\u7f1d\u7684\u8bd5\u9a8c\u8bbe\u8ba1\uff0c\u65b0\u836f\u5f00\u53d1\u4f1a\u53d8\u5f97\u66f4\u6709\u6548\u7387\uff0c\u201d Gottlieb\u535a\u58eb\u8bf4\u9053\uff1a\u201c\u6574\u4e2a\u8bd5\u9a8c\u6d41\u7a0b\u4ec5\u9700\u8981\u51e0\u767e\u540d\u60a3\u8005\u5c31\u80fd\u5b8c\u6210\u3002\u201d<\/strong><\/span><\/p>\n<p style=\"line-height: 1.75em;\"><span style=\"font-size: 15px;\"><br  \/><\/span><\/p>\n<section style=\"white-space: normal;max-width: 100%;box-sizing: border-box;color: rgb(51, 51, 51);\">\n<section class=\"\"  style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<section class=\"\" style=\"margin-top: 10px;max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<section class=\"\" style=\"padding-left: 5px;max-width: 100%;box-sizing: border-box;display: inline-block;width: 638.4px;border-width: 0px 0px 0px 10px;border-style: solid;border-left-color: rgb(0, 112, 192);border-right-color: rgb(0, 112, 192);word-wrap: break-word !important;\">\n<section class=\"\"  style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;color: rgb(0, 112, 192);word-wrap: break-word !important;\">\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 15px;box-sizing: border-box !important;word-wrap: break-word !important;\">\u66ff\u4ee3\u7ec8\u70b9<\/span><\/strong><\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"\"  style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<section class=\"\" style=\"margin-bottom: 8px;max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;background-color: rgb(0, 112, 192);height: 1px;word-wrap: break-word !important;\"><\/section>\n<\/section>\n<\/section>\n<\/section>\n<p style=\"line-height: 1.75em;\"><br  \/><\/p>\n<p style=\"line-height: 1.75em;\"><span style=\"font-size: 15px;\">\u5728\u53d1\u8a00\u4e2d\uff0cGottlieb\u535a\u58eb\u82b1\u4e86\u5f88\u5927\u7684\u7bc7\u5e45\u4ecb\u7ecd\u66ff\u4ee3\u7ec8\u70b9\u3002\u8fd9\u5bf9\u4e8e\u90a3\u4e9b\u9700\u8981\u5f88\u4e45\u624d\u80fd\u83b7\u5f97\u7ed3\u679c\u7684\u4e34\u5e8a\u8bd5\u9a8c\uff0c\u6216\u662f\u5bf9\u4e8e\u90a3\u4e9b\u6211\u4eec\u5df2\u6709\u8db3\u591f\u4e86\u89e3\u7684\u4e34\u5e8a\u8bd5\u9a8c\uff08\u6bd4\u5982\u63a7\u5236\u8840\u538b\uff0c\u6216\u8005\u964d\u4f4eHIV\u75c5\u6bd2\u91cf\uff09\u800c\u8a00\uff0c\u662f\u4e00\u4e2a\u5f88\u597d\u7684\u9009\u62e9\u3002<\/span><\/p>\n<p><br  \/><\/p>\n<p style=\"line-height: 1.75em;\"><span style=\"font-size: 15px;\">\u4e8b\u5b9e\u4e0a\uff0c\u5728\u764c\u75c7\u9886\u57df\uff0c\u66ff\u4ee3\u7ec8\u70b9\u5df2\u7ecf\u5f97\u5230\u4e86\u8bb8\u591a\u4eba\u7684\u8ba4\u53ef\uff0c\u5e76\u6210\u4e3a\u4e86\u8bb8\u591a\u5e38\u89c4\u83b7\u6279\uff0c\u751a\u81f3\u662f\u52a0\u901f\u83b7\u6279\u6240\u8003\u91cf\u7684\u5bf9\u8c61\u3002\u8b6c\u5982\u5bf9\u4e8e\u6025\u6027\u6dcb\u5df4\u6027\u767d\u8840\u75c5\u6765\u8bf4\uff0c\u6700\u5c0f\u75c5\u7076\u75be\u75c5\u7f13\u89e3\u7387\uff08minimal residual disease response rate\uff09\u662f\u5176\u7597\u6cd5\u52a0\u901f\u83b7\u6279\u7684\u66ff\u4ee3\u7ec8\u70b9\uff1b\u800c\u5bf9\u672a\u6269\u6563\u7684\u53bb\u52bf\u62b5\u6297\u6027\u524d\u5217\u817a\u764c\u6765\u8bf4\uff0c\u65e0\u8f6c\u79fb\u751f\u5b58\u671f\uff08metastasis-free survival\uff09\u4e5f\u662f\u83b7\u6279\u6240\u5ba1\u67e5\u7684\u4e00\u4e2a\u4e34\u5e8a\u7ec8\u70b9\u3002<\/span><\/p>\n<p style=\"line-height: 1.75em;\"><span style=\"font-size: 15px;\"><br  \/><\/span><\/p>\n<p style=\"text-align: center;\"><img class=\"\"       style=\"\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/08\/beepress6-1533787279.jpg\" alt=\"FDA\u5c40\u957f\u6700\u65b0\u8bb2\u8bdd\uff1a\u4e34\u5e8a\u8bd5\u9a8c\u6539\u9769\u52bf\u5728\u5fc5\u884c\uff01\" title=\"FDA\u5c40\u957f\u6700\u65b0\u8bb2\u8bdd\uff1a\u4e34\u5e8a\u8bd5\u9a8c\u6539\u9769\u52bf\u5728\u5fc5\u884c\uff01\"  \/><\/p>\n<p style=\"line-height: 1.75em;\"><span style=\"font-size: 15px;\"><\/span><\/p>\n<p style=\"white-space: normal;text-align: center;line-height: 1.75em;\"><strong><span style=\"font-size: 14px;color: rgb(0, 112, 192);\">\u25b2\u5173\u6ce8\u836f\u660e\u5eb7\u5fb7\u5fae\u4fe1\u53f7\uff0c\u5728\u540e\u53f0\u56de\u590d\u201c\u66ff\u4ee3\u7ec8\u70b9\u201d\uff0c\u5373\u53ef\u83b7\u53d6\u5b8c\u6574\u66ff\u4ee3\u7ec8\u70b9\u5217\u8868\uff08\u5171\u4e03\u9875\uff09<\/span><\/strong><\/p>\n<p><br  \/><\/p>\n<p style=\"line-height: 1.75em;\"><span style=\"font-size: 15px;\">\u201c\u5728\u764c\u75c7\u9886\u57df\u4f7f\u7528\u66ff\u4ee3\u7ec8\u70b9\uff0c\u80fd\u5c06\u5145\u6ee1\u6f5c\u529b\u7684\u7597\u6cd5\u9001\u5230\u9ad8\u98ce\u9669\u7684\u60a3\u8005\u8eab\u8fb9\u3002\u4e0e\u8fc7\u53bb\u7684\u4e34\u5e8a\u7ec8\u70b9\u76f8\u6bd4\uff0c\u66ff\u4ee3\u7ec8\u70b9\u80fd\u5c06\u8fdb\u7a0b\u52a0\u5feb\u597d\u51e0\u5e74\uff0c\u201dGottlieb\u535a\u58eb\u8bf4\u9053\uff1a\u201c\u5728\u67d0\u4e9b\u6848\u4f8b\u4e2d\uff0c\u5b83\u8fd8\u80fd\u589e\u52a0\u62b5\u8fbe\u957f\u671f\u7f13\u89e3\u7684\u51e0\u7387\u3002\u201d<\/span><\/p>\n<p><span style=\"color: rgb(255, 255, 255);font-size: 15px;\">\u672c\u6587\u6765\u6e90\uff1a\u836f\u660e\u5eb7\u5fb7<\/span><\/p>\n<p style=\"line-height: 1.75em;\"><span style=\"font-size: 15px;\">\u7f8e\u56fdFDA\u4e5f\u4e3a\u6211\u4eec\u63d0\u4f9b\u4e86\u4e00\u5f20\u5b8c\u6574\u7684\u66ff\u4ee3\u7ec8\u70b9\u5217\u8868\u3002\u5b83\u5c06\u662f\u8bf8\u591a\u5316\u5b66\u836f\u6216\u751f\u7269\u5236\u5242\u83b7\u6279\u7684\u57fa\u7840\u3002<strong>\u5173\u6ce8\u836f\u660e\u5eb7\u5fb7\u5fae\u4fe1\u53f7\uff0c\u5728\u540e\u53f0\u56de\u590d\u201c\u66ff\u4ee3\u7ec8\u70b9\u201d\uff0c\u5373\u53ef\u83b7\u53d6\u5b8c\u6574\u66ff\u4ee3\u7ec8\u70b9\u5217\u8868\u3002<\/strong><\/span><\/p>\n<p><br  \/><\/p>\n<section style=\"white-space: normal;max-width: 100%;box-sizing: border-box;color: rgb(51, 51, 51);\">\n<section class=\"\"  style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<section class=\"\" style=\"margin-top: 10px;max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<section class=\"\" style=\"padding-left: 5px;max-width: 100%;box-sizing: border-box;display: inline-block;width: 638.4px;border-width: 0px 0px 0px 10px;border-style: solid;border-left-color: rgb(0, 112, 192);border-right-color: rgb(0, 112, 192);word-wrap: break-word !important;\">\n<section class=\"\"  style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;color: rgb(0, 112, 192);word-wrap: break-word !important;\">\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 15px;box-sizing: border-box !important;word-wrap: break-word !important;\">15\u5e74\u6765\u7684\u7a81\u7834<\/span><\/strong><\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"\"  style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<section class=\"\" style=\"margin-bottom: 8px;max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;background-color: rgb(0, 112, 192);height: 1px;word-wrap: break-word !important;\"><\/section>\n<\/section>\n<\/section>\n<\/section>\n<p><br  \/><\/p>\n<p style=\"line-height: 1.75em;\"><span style=\"font-size: 15px;\">\u5728\u8fd9\u4efd\u53e3\u5934\u62a5\u544a\u7684\u6700\u540e\uff0cGottlieb\u535a\u58eb\u8bb2\u8ff0\u4e86\u81ea\u4ed6\u52a0\u5165\u7f8e\u56fdFDA\u768415\u5e74\u6765\uff0c\u4eba\u7c7b\u5728\u75be\u75c5\u6cbb\u7597\u9886\u57df\u53d6\u5f97\u7684\u5de8\u5927\u8fdb\u5c55\u3002\u4ed6\u8bf4\uff1a<\/span><\/p>\n<p><br  \/><\/p>\n<p style=\"line-height: 1.75em;\"><span style=\"font-size: 15px;\">\u201c\u5f53\u6211\u57282003\u5e74\u9996\u5ea6\u52a0\u5165FDA\u4e4b\u9645\uff0cHER2\u9633\u6027\u7684\u8f6c\u79fb\u6027\u4e73\u817a\u764c\u662f\u6700\u4e3a\u53ef\u6015\u7684\u764c\u75c7\u8bca\u65ad\u3002<strong>\u90a3\u65f6\uff0c\u80bf\u7624\u514d\u75ab\u7597\u6cd5\u627e\u4e0d\u5230\u51fa\u8def\uff0c\u57fa\u56e0\u7597\u6cd5\u5904\u4e8e\u505c\u6446\uff0c\u57fa\u56e0\u7f16\u8f91\u66f4\u662f\u65e0\u4ece\u8bf4\u8d77\u3002<\/strong>\u201d<\/span><\/p>\n<p><br  \/><\/p>\n<p style=\"line-height: 1.75em;\"><span style=\"font-size: 15px;\">\u201c\u60a3\u6709\u987d\u56fa\u6027\u767d\u8840\u75c5\u548c\u6dcb\u5df4\u7624\u7684\u60a3\u8005\uff0c\u53ea\u80fd\u60b2\u5267\u6027\u5730\u7528\u6708\u6765\u8ba1\u7b97\u81ea\u5df1\u7684\u751f\u547d\u3002\u60a3\u6709\u4e19\u809d\u7684\u60a3\u8005\u8fd8\u5728\u4f7f\u7528\u5229\u5df4\u97e6\u6797\u548c\u5e72\u6270\u7d20\u8fd9\u4e9b\u6bd2\u6027\u8f83\u5f3a\uff0c\u8010\u53d7\u5f88\u5dee\u7684\u836f\u7269\u3002\u5bf9\u4e8e\u8fd9\u4e9b\u60a3\u8005\uff0c\u6211\u4eec\u5f88\u5c11\u80fd\u5e26\u6765\u6cbb\u6108\u3002\u201d<\/span><\/p>\n<p><br  \/><\/p>\n<p style=\"line-height: 1.75em;\"><span style=\"font-size: 15px;\">\u201c\u513f\u7ae52\u578b\u7cd6\u5c3f\u75c5\u60a3\u8005\u7684\u7236\u6bcd\uff0c\u6bcf\u5929\u665a\u4e0a\u9694\u51e0\u4e2a\u5c0f\u65f6\uff0c\u5c31\u8981\u53eb\u9192\u81ea\u5df1\u7684\u5b69\u5b50\uff0c\u6d4b\u91cf\u4ed6\u4eec\u7684\u8840\u7cd6\u6c34\u5e73\uff0c\u51b3\u5b9a\u8981\u4e0d\u8981\u4f7f\u7528\u80f0\u5c9b\u7d20\u3002\u6211\u4eec\u8fd8\u6ca1\u6709\u6570\u5b57\u533b\u7597\u7684\u6982\u5ff5\uff0c\u667a\u80fd\u624b\u673a\u3001app\u5e93\u90fd\u8fd8\u4e0d\u5b58\u5728\uff0c\u7528\u4e8e\u533b\u5b66\u7684\u4eba\u5de5\u667a\u80fd\u8fd8\u5904\u4e8e\u840c\u82bd\u3002\u201d<\/span><\/p>\n<p><br  \/><\/p>\n<p style=\"line-height: 1.75em;\"><strong><span style=\"font-size: 15px;\">\u201c\u4ec5\u4ec5\u662f15\u5e74\uff0c\u4e00\u5207\u53d1\u751f\u4e86\u5982\u6b64\u5927\u7684\u4e0d\u540c\uff01\u201d<\/span><\/strong><\/p>\n<p><br  \/><\/p>\n<p style=\"text-align: center;\">\n<p style=\"text-align: center;\"><span style=\"font-size: 14px;text-decoration: underline;color: rgb(0, 112, 192);\"><strong><span style=\"color: rgb(0, 112, 192);font-size: 14px;\"><a href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MzAwMDA5NTIxNQ==&amp;mid=2649964215&amp;idx=1&amp;sn=d4ca7d1d6733e79f87c9811ce84439f4&amp;chksm=82e9b837b59e3121da05f5e6bf36dc6b6394cfdbca092af59db469d1cedec990cdcbb148ada4&amp;scene=21#wechat_redirect\" target=\"_blank\" style=\"font-size: 14px;text-decoration: underline;color: rgb(0, 112, 192);\"><strong style=\"text-align: center;white-space: normal;\"><span style=\"font-size: 14px;color: rgb(0, 112, 192);\">\u25b2<\/span><\/strong>\u836f\u660e\u5eb7\u5fb7\u72ec\u5bb6\u6df1\u5ea6\u62a5\u544a\uff1a\u514d\u75ab\u7597\u6cd5\u80fd\u6d88\u706d\u764c\u75c7\u5417\uff1f<\/a>\uff08\u56fe\u7247\u6765\u6e90\uff1a123RF\uff09<\/span><\/strong><\/span><br  \/><\/p>\n<p><br  \/><\/p>\n<p style=\"line-height: 1.75em;\"><span style=\"font-size: 15px;\">\u201c\u514d\u75ab\u68c0\u67e5\u70b9\u6291\u5236\u5242\u6b63\u4e3a\u4e00\u4e9b\u8f6c\u79fb\u6027\u9ed1\u8272\u7d20\u7624\u548c\u80ba\u764c\u60a3\u8005\u5e26\u6765\u524d\u6240\u672a\u6709\u7684\u6cbb\u7597\u7ed3\u679c\uff1b\u4e19\u809d\u7684\u6cbb\u6108\u7387\u8fbe\u5230\u4e8695%\u4ee5\u4e0a\uff0c\u7597\u6cd5\u4e0d\u4f46\u66f4\u6709\u6548\uff0c\u6bd2\u6027\u8fd8\u66f4\u5c0f\uff1b\u7ecf\u8fc7\u57fa\u56e0\u7f16\u8f91\u7684T\u7ec6\u80de\u5728\u81f3\u591a60%\u7684\u60a3\u8005\u4e2d\u5c55\u73b0\u51fa\u4e86\u6301\u4e45\u7684\u7f13\u89e3\u7597\u6548\uff0c\u8981\u77e5\u9053\uff0c\u8fd9\u4e9b\u60a3\u8005\u5f97\u7684\u90fd\u662f\u5bf9\u836f\u7269\u4ea7\u751f\u8010\u53d7\u7684\u81f4\u547d\u767d\u8840\u75c5\u548c\u6dcb\u5df4\u7624\uff1b\u6162\u6027\u6dcb\u5df4\u6027\u767d\u8840\u75c5\u548c\u6162\u6027\u9aa8\u9ad3\u6027\u767d\u8840\u75c5\u80fd\u88ab\u5f53\u4f5c\u6162\u6027\u75be\u75c5\u6765\u8fdb\u884c\u63a7\u5236\u548c\u7ba1\u7406\uff1b\u8bb8\u591a\u8840\u6db2\u764c\u75c7\u60a3\u8005\u7684\u75c5\u60c5\u5df2\u7ecf\u7a33\u5b9a\u4e86\u6570\u5e74\uff0c\u751a\u81f3\u662f\u6570\u5341\u5e74\u3002\u201d<\/span><\/p>\n<p><span style=\"color: rgb(255, 255, 255);font-size: 15px;\">\u672c\u6587\u6765\u6e90\uff1a\u836f\u660e\u5eb7\u5fb7<\/span><\/p>\n<p style=\"line-height: 1.75em;\"><span style=\"font-size: 15px;\">\u201c\u5728HER2\u9633\u6027\u7684\u8f6c\u79fb\u6027\u4e73\u817a\u764c\u6cbb\u7597\u4e2d\uff0c\u8bb8\u591a\u65b0\u7ebf\u7597\u6cd5\u83b7\u6279\u3002\u901a\u8fc7\u91c7\u53d6\u5168\u65b0\u7684\u4e34\u5e8a\u7ec8\u70b9\uff0c\u8f85\u4ee5\u624b\u672f\uff0c\u6211\u4eec\u4e3a\u8fd9\u4e9b\u60a3\u8005\u62d3\u5c55\u4e86\u6709\u6548\u7684\u6cbb\u7597\u9009\u62e9\uff0c\u964d\u4f4e\u4e86\u5979\u4eec\u75be\u75c5\u590d\u53d1\u7684\u98ce\u9669\u30021\u578b\u7cd6\u5c3f\u75c5\u60a3\u8005\u4e5f\u5df2\u7ecf\u6709\u4e86FDA\u6279\u51c6\u7684\u95ed\u73af\u80f0\u5c9b\u7d20\u9012\u9001\u7cfb\u7edf\uff0c\u5b83\u80fd\u901a\u8fc7\u7b97\u6cd5\uff0c\u57fa\u4e8e\u6bcf5\u5206\u949f\u4e00\u6b21\u7684\u5b9e\u65f6\u6570\u636e\u76d1\u63a7\uff0c\u9012\u9001\u57fa\u7840\u6c34\u5e73\u7684\u80f0\u5c9b\u7d20\uff0c\u4ece\u800c\u51cf\u5c11\uff0c\u751a\u81f3\u5f7b\u5e95\u6d88\u9664\u7531\u4e8e\u8840\u7cd6\u76d1\u6d4b\u5e26\u6765\u7684\u7761\u7720\u5e72\u6270\u3002\u201d<\/span><\/p>\n<p style=\"line-height: 1.75em;\"><span style=\"font-size: 15px;\"><br  \/><\/span><\/p>\n<p style=\"line-height: 1.75em;\"><span style=\"font-size: 15px;\">Gottlieb\u535a\u58eb\u603b\u7ed3\u8bf4\uff0c\u8fd9\u6b63\u662f\u5bf9\u4e34\u5e8a\u8bd5\u9a8c\u8fdb\u884c\u73b0\u4ee3\u5316\u6539\u9769\u7684\u52a8\u529b\u3002<strong>\u4e3a\u4e86\u8ba9\u60a3\u8005\u5c3d\u5feb\u5f97\u5230\u6cbb\u7597\uff0c\u8fd9\u6837\u7684\u6539\u9769\u52bf\u5728\u5fc5\u884c\uff01<\/strong><\/span><\/p>\n<p style=\"line-height: 1.75em;\"><span style=\"font-size: 15px;\"><strong><br  \/><\/strong><\/span><\/p>\n<p style=\"line-height: 1.75em;\"><span style=\"font-size: 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