{"id":29474,"date":"2018-08-01T01:00:00","date_gmt":"2018-08-09T04:01:50","guid":{"rendered":"http:\/\/www.05921.net\/index.php\/2018\/08\/09\/%e9%80%9f%e9%80%92-%e5%85%8d%e7%96%ab%e7%96%97%e6%b3%95%e5%86%8d%e8%8e%b7%e7%aa%81%e7%a0%b4%e6%80%a7%e7%96%97%e6%b3%95%e8%ae%a4%e5%ae%9a%ef%bc%8c%e6%b2%bb%e7%96%97%e5%ad%90%e5%ae%ab%e5%86%85\/"},"modified":"2018-08-09T12:01:52","modified_gmt":"2018-08-09T04:01:52","slug":"%e9%80%9f%e9%80%92-%e5%85%8d%e7%96%ab%e7%96%97%e6%b3%95%e5%86%8d%e8%8e%b7%e7%aa%81%e7%a0%b4%e6%80%a7%e7%96%97%e6%b3%95%e8%ae%a4%e5%ae%9a%ef%bc%8c%e6%b2%bb%e7%96%97%e5%ad%90%e5%ae%ab%e5%86%85","status":"publish","type":"post","link":"https:\/\/www.05921.net\/index.php\/29474\/","title":{"rendered":"\u901f\u9012 | \u514d\u75ab\u7597\u6cd5\u518d\u83b7\u7a81\u7834\u6027\u7597\u6cd5\u8ba4\u5b9a\uff0c\u6cbb\u7597\u5b50\u5bab\u5185\u819c\u764c"},"content":{"rendered":"<div class=\"bpp-post-content\">\n<p style=\"white-space: normal;line-height: 1.75em;\"><strong style=\"max-width: 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!important;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;line-height: 32px;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;line-height: 1.75em;font-family: \u5fae\u8f6f\u96c5\u9ed1, sans-serif;font-size: 15px;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;color: rgb(0, 112, 192);font-family: \u6977\u4f53;box-sizing: border-box !important;word-wrap: break-word !important;\">\u258e\u836f\u660e<\/span><\/strong><strong style=\"max-width: 100%;line-height: 1.75em;font-family: \u5fae\u8f6f\u96c5\u9ed1, sans-serif;font-size: 15px;box-sizing: border-box 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\u514d\u75ab\u7597\u6cd5\u518d\u83b7\u7a81\u7834\u6027\u7597\u6cd5\u8ba4\u5b9a\uff0c\u6cbb\u7597\u5b50\u5bab\u5185\u819c\u764c\" title=\"\u901f\u9012 | \u514d\u75ab\u7597\u6cd5\u518d\u83b7\u7a81\u7834\u6027\u7597\u6cd5\u8ba4\u5b9a\uff0c\u6cbb\u7597\u5b50\u5bab\u5185\u819c\u764c\"  \/><\/p>\n<p style=\"text-align: center;\"><br  \/><\/p>\n<p style=\"line-height: 1.75em;\"><span style=\"font-size: 15px;\">\u51e0\u4e4e\u6240\u6709\u7684\u5b50\u5bab\u764c\u75c7\u90fd\u662f\u5b50\u5bab\u5185\u819c\u764c\u30022018\u5e74\u9884\u8ba1\u5c06\u6709\u7ea663,230\u4f8b\u5b50\u5bab\u764c\u65b0\u53d1\u75c5\u4f8b\uff0c\u5e76\u5c06\u6709\u7ea611,350\u4eba\u6b7b\u4e8e\u5b50\u5bab\u764c\u3002\u5b50\u5bab\u5185\u819c\u764c\u60a3\u8005\u7684\u751f\u5b58\u671f\u968f\u7740\u75be\u75c5\u8fdb\u5c55\uff0c\u6709\u660e\u663e\u4e0b\u964d\u2014\u2014<\/span><strong style=\"font-size: 15px;\">Ia\u671f\u5b50\u5bab\u5185\u819c\u764c\u5973\u6027\u76845\u5e74\u751f\u5b58\u7387\u4e3a88\uff05\uff0c\u800cIVb\u671f\u5973\u6027\u76845\u5e74\u751f\u5b58\u7387\u5219\u4e0b\u964d\u81f315\uff05<\/strong><span style=\"font-size: 15px;\">\u3002\u5979\u4eec\u6025\u9700\u6709\u6548\u7597\u6cd5\u6765\u63a7\u5236\u75be\u75c5\uff0c\u5ef6\u957f\u751f\u547d\u3002<\/span><br  \/><\/p>\n<p><span style=\"color: rgb(255, 255, 255);font-size: 15px;\">\u672c\u6587\u6765\u6e90\uff1a\u836f\u660e\u5eb7\u5fb7<\/span><\/p>\n<p style=\"line-height: 1.75em;\"><span style=\"font-size: 15px;\">Lenvima\u52a0Keytruda\u7684\u7ec4\u5408\u7597\u6cd5\u7531\u536b\u6750\u548c\u9ed8\u6c99\u4e1c\u8054\u5408\u5f00\u53d1\u3002<strong>\u8fd9\u662fLenvima\u83b7\u5f97\u7684\u7b2c\u4e09\u4e2a\u7a81\u7834\u6027\u7597\u6cd5\u8ba4\u5b9a\uff0c\u4e5f\u662fLenvima\u52a0Keytruda\u7ec4\u5408\u7597\u6cd5\u83b7\u5f97\u7684\u7b2c\u4e8c\u4e2a\u7a81\u7834\u6027\u7597\u6cd5\u8ba4\u5b9a<\/strong>\uff08\u7b2c\u4e00\u4e2a\u8ba4\u5b9a\u4e8e\u4eca\u5e741\u6708\u83b7\u5f97\uff0c\u6cbb\u7597<\/span><a href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MzAwMDA5NTIxNQ==&amp;mid=2649969298&amp;idx=2&amp;sn=ed786a034deba4ccecc7af86ac1ee0ba&amp;chksm=82e9d412b59e5d041d2c27d0184280199d81fe14ff228f7c97dea8d15984e6a9ce1d87711803&amp;scene=21#wechat_redirect\" target=\"_blank\" style=\"text-decoration: underline;font-size: 15px;color: rgb(0, 112, 192);\"><span style=\"font-size: 15px;color: rgb(0, 112, 192);\">\u80be\u7ec6\u80de\u764c<\/span><\/a><span style=\"font-size: 15px;\">\uff09\u3002<\/span><\/p>\n<p style=\"text-align: center;\"><img class=\"\"       style=\"\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/08\/beepress0-1533787311.jpg\" alt=\"\u901f\u9012 | \u514d\u75ab\u7597\u6cd5\u518d\u83b7\u7a81\u7834\u6027\u7597\u6cd5\u8ba4\u5b9a\uff0c\u6cbb\u7597\u5b50\u5bab\u5185\u819c\u764c\" title=\"\u901f\u9012 | \u514d\u75ab\u7597\u6cd5\u518d\u83b7\u7a81\u7834\u6027\u7597\u6cd5\u8ba4\u5b9a\uff0c\u6cbb\u7597\u5b50\u5bab\u5185\u819c\u764c\"  \/><\/p>\n<p style=\"text-align: center;\"><br  \/><\/p>\n<p style=\"line-height: 1.75em;\"><span style=\"font-size: 15px;\">\u8fd9\u4e00\u7a81\u7834\u6027\u7597\u6cd5\u8ba4\u5b9a\u7684\u9881\u5e03\u662f\u57fa\u4e8e\u4e34\u5e8a\u8bd5\u9a8cStudy 111\/KEYNOTE-146\u4e2dEC\u961f\u5217\u7684\u4e2d\u671f\u7ed3\u679c\uff0c\u8be5\u7ed3\u679c\u4e8e\u4eca\u5e746\u6708\u5728\u7b2c54\u5c4a\u7f8e\u56fd\u4e34\u5e8a\u80bf\u7624\u5b66\u4f1a\uff08ASCO\uff09\u5e74\u4f1a\u4e0a\u53d1\u8868\u3002Study 111\/KEYNOTE-146 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trial\uff09\uff0c\u8bc4\u4f30\u4e86Lenvima\uff08\u6bcf\u592920\u6beb\u514b\uff09\u52a0Keytruda\uff08\u6bcf\u4e09\u5468\u9759\u8109\u6ce8\u5c04200\u6beb\u514b\uff09\u7ec4\u5408\u7597\u6cd5\u5bf9\u9009\u5b9a\u5b9e\u4f53\u7624\u60a3\u8005\u7684\u7597\u6548\u548c\u5b89\u5168\u6027\uff0c\u5305\u62ec\u80be\u7ec6\u80de\u764c\u3001EC\u3001\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u3001\u5c3f\u8def\u4e0a\u76ae\u764c\u3001\u9cde\u72b6\u7ec6\u80de\u5934\u9888\u764c\u548c\u9ed1\u8272\u7d20\u7624\u30021b\u671f\u7814\u7a76\u7684\u4e3b\u8981\u7ec8\u70b9\u662f\u786e\u5b9aLenvima\u52a0Keytruda\u7ec4\u5408\u7597\u6cd5\u7684\u6700\u5927\u8010\u53d7\u5242\u91cf\u30022\u671f\u7814\u7a76\u7684\u4e3b\u8981\u7ec8\u70b9\u662f\u5728\u7b2c24\u5468\u65f6\u7531\u7814\u7a76\u8005\u8bc4\u4f30\u7684\u57fa\u4e8e\u514d\u75ab\u76f8\u5173RECIST\uff08irRECIST\uff09\u7684\u5ba2\u89c2\u7f13\u89e3\u7387\uff08ORR\uff09\u3002\u6b21\u8981\u7ec8\u70b9\u5305\u62ecORR\u3001\u65e0\u8fdb\u5c55\u751f\u5b58\u671f\uff08PFS\uff09\u548c\u83b7\u5f97\u5b8c\u5168\u6216\u90e8\u5206\u7f13\u89e3\u7684\u6301\u7eed\u65f6\u95f4\u3002\u76ee\u524d\uff0c2\u671f\u7814\u7a76\u90e8\u5206\u6b63\u5728\u8fdb\u884cEC\u961f\u5217\u6269\u5c55\u3002<\/span><br 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Baynes\u535a\u58eb\u8bf4\uff1a\u201c\u6211\u4eec\u5c06\u7ee7\u7eed\u4e0e\u536b\u6750\u5bc6\u5207\u5408\u4f5c\uff0c\u4ee5\u5efa\u7acbLenvima\/Keytruda\u7ec4\u5408\u5728\u665a\u671f\u5b50\u5bab\u5185\u819c\u764c\u4e2d\u7684\u5f3a\u5927\u6570\u636e\uff0c\u52aa\u529b\u4e3a\u8fd9\u4e9b\u60a3\u8005\u63d0\u4f9b\u65b0\u9009\u62e9\uff0c\u5e76\u89e3\u51b3\u91cd\u8981\u7684\u672a\u6ee1\u8db3\u9700\u6c42\u3002\u201d<\/span><\/p>\n<p><br  \/><\/p>\n<p style=\"line-height: 1.75em;\"><span style=\"font-size: 15px;\">\u201c\u6211\u4eec\u8bbe\u8ba1Study 111\u4ee5\u5c3d\u53ef\u80fd\u9ad8\u6548\u5730\u4e86\u89e3Lenvima\/Keytruda\u7ec4\u5408\uff0c\u5c3d\u5feb\u4e3a\u6709\u9700\u8981\u7684\u60a3\u8005\u63d0\u4f9b\u6f5c\u5728\u7684\u65b0\u6cbb\u7597\u9009\u62e9\uff0c\u201d\u536b\u6750\u80bf\u7624\u4e8b\u4e1a\u90e8\u526f\u603b\u88c1\u517c\u9996\u5e2d\u836f\u7269\u521b\u5236\u5b98Takashi Owa\u535a\u58eb\u8bf4\uff1a\u201c\u6211\u4eec\u5bf9\u5728\u5b50\u5bab\u5185\u819c\u764c\u60a3\u8005\u4e2d\u89c2\u5bdf\u5230\u7684\u6301\u7eed\u6d3b\u6027\u611f\u5230\u9f13\u821e\uff0cLenvima\/Keytruda\u7ec4\u5408\u6700\u65b0\u83b7\u5f97\u7684\u7a81\u7834\u6027\u7597\u6cd5\u8ba4\u5b9a\u52a0\u5f3a\u4e86\u6211\u4eec\u4f5c\u4e3a\u4eba\u7c7b\u5065\u5eb7\u62a4\u7406\u4f7f\u547d\u4e00\u90e8\u5206\u7684\u627f\u8bfa\uff0c\u5c3d\u5feb\u4e3a\u5b50\u5bab\u5185\u819c\u764c\u60a3\u8005\u5e26\u6765\u76ca\u5904\u3002\u201d<\/span><\/p>\n<p style=\"white-space: normal;\"><br  \/><\/p>\n<p style=\"white-space: normal;line-height: normal;\"><span style=\"font-size: 10px;color: rgb(178, 178, 178);\">\u53c2\u8003\u8d44\u6599\uff1a<\/span><\/p>\n<p style=\"white-space: normal;line-height: normal;\"><span style=\"font-size: 10px;color: rgb(178, 178, 178);\">[1]&nbsp;<\/span><span style=\"color: rgb(178, 178, 178);font-size: 10px;\">Eisai and Merck Announce FDA Grants Breakthrough Therapy Designation for LENVIMA\u00ae (lenvatinib) in Combination with KEYTRUDA\u00ae (pembrolizumab)<\/span><\/p>\n<p style=\"white-space: normal;line-height: normal;\"><span style=\"color: rgb(178, 178, 178);font-size: 10px;\">[2] Eisai\u5b98\u65b9\u7f51\u7ad9<\/span><\/p>\n<p style=\"white-space: normal;line-height: normal;\"><span style=\"color: rgb(178, 178, 178);font-size: 10px;\"><br  \/><\/span><\/p>\n<p style=\"line-height: normal;\"><span style=\"max-width: 100%;font-size: 10px;color: rgb(178, 178, 178);box-sizing: border-box !important;word-wrap: break-word !important;\">\u672c\u6587\u6765\u81ea\u836f\u660e\u5eb7\u5fb7\u5fae\u4fe1\u56e2\u961f\uff0c\u6b22\u8fce\u8f6c\u53d1\u5230\u670b\u53cb\u5708\uff0c\u8c22\u7edd\u8f6c\u8f7d\u5230\u5176\u4ed6\u5e73\u53f0\uff1b\u5982\u6709\u5f00\u8bbe\u767d\u540d\u5355\u9700\u6c42\uff0c\u8bf7\u5728\u6587\u7ae0\u5e95\u90e8\u7559\u8a00\uff1b\u5982\u6709\u5176\u4ed6\u5408\u4f5c\u9700\u6c42\uff0c\u8bf7\u8054\u7cfbwuxi_media@wuxiapptec.com<\/span><\/p>\n<p style=\"white-space: normal;max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><span style=\"max-width: 100%;font-size: 10px;color: rgb(178, 178, 178);box-sizing: border-box !important;word-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/span><\/p>\n<p style=\"white-space: normal;max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><img class=\"__bg_gif\"      style=\"box-sizing: border-box !important;word-wrap: break-word !important;width: auto !important;visibility: visible !important;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/08\/beepress9-1533787311.gif\" alt=\"\u901f\u9012 | \u514d\u75ab\u7597\u6cd5\u518d\u83b7\u7a81\u7834\u6027\u7597\u6cd5\u8ba4\u5b9a\uff0c\u6cbb\u7597\u5b50\u5bab\u5185\u819c\u764c\" title=\"\u901f\u9012 | \u514d\u75ab\u7597\u6cd5\u518d\u83b7\u7a81\u7834\u6027\u7597\u6cd5\u8ba4\u5b9a\uff0c\u6cbb\u7597\u5b50\u5bab\u5185\u819c\u764c\"  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