{"id":30079,"date":"2018-08-08T01:00:00","date_gmt":"2018-08-09T04:05:35","guid":{"rendered":"http:\/\/www.05921.net\/index.php\/2018\/08\/09\/%e3%80%90%e6%8b%9b%e5%8b%9f%e6%82%a3%e8%80%85%e3%80%91%e6%97%a2%e5%be%80%e6%8e%a5%e5%8f%97%e8%bf%87%e8%87%b3%e5%b0%91%e4%b8%80%e7%a7%8d%e7%b3%bb%e7%bb%9f%e6%b2%bb%e7%96%97%e7%9a%84%e6%99%9a%e6%9c%9f\/"},"modified":"2018-08-09T12:05:37","modified_gmt":"2018-08-09T04:05:37","slug":"%e3%80%90%e6%8b%9b%e5%8b%9f%e6%82%a3%e8%80%85%e3%80%91%e6%97%a2%e5%be%80%e6%8e%a5%e5%8f%97%e8%bf%87%e8%87%b3%e5%b0%91%e4%b8%80%e7%a7%8d%e7%b3%bb%e7%bb%9f%e6%b2%bb%e7%96%97%e7%9a%84%e6%99%9a%e6%9c%9f","status":"publish","type":"post","link":"https:\/\/www.05921.net\/index.php\/30079\/","title":{"rendered":"\u3010\u62db\u52df\u60a3\u8005\u3011\u65e2\u5f80\u63a5\u53d7\u8fc7\u81f3\u5c11\u4e00\u79cd\u7cfb\u7edf\u6cbb\u7597\u7684\u665a\u671f\u809d\u7ec6\u80de\u764c\u4e2d\u8bc4\u4f30TORC1\/TORC2\u6291\u5236\u5242ATG-008\u7684\u4e00\u9879 2 \u671f\u5f00\u653e\u6027\u4e34\u5e8a\u8bd5\u9a8c"},"content":{"rendered":"
\n
<\/mpcps><\/section>\n

<\/span>
<\/p>\n

1.  <\/span>\u8bd5\u9a8c\u836f\u7269\u7b80\u4ecb<\/span><\/p>\n

ATG-008<\/span>\u662f<\/span>TORC1\/TORC2 <\/span>\u53cc\u91cd\u6291\u5236\u5242\uff0c\u672c\u8bd5\u9a8c\u7684\u9002\u5e94\u75c7\u662f\u65e2\u5f80\u63a5\u53d7\u8fc7\u81f3\u5c11\u4e00\u79cd\u7cfb\u7edf\u6cbb\u7597\u7684<\/span>HBV+<\/span>\u665a\u671f\u809d\u7ec6\u80de\u764c\u3002<\/span><\/span><\/p>\n

 <\/span><\/p>\n

2.  <\/span>\u8bd5\u9a8c\u76ee\u7684<\/span><\/p>\n

<\/span>\u5728\u65e2\u5f80\u63a5\u53d7\u8fc7\u81f3\u5c11\u4e00\u79cd\u7cfb\u7edf\u6cbb\u7597\u65b9\u6848\u7684HBV+ HCC \u53d7\u8bd5\u8005\u4e2d\u8bc4\u4f30ATG-008 \u7684\u836f\u4ee3\u52a8\u529b\u5b66\uff08PK\uff09\u3001\u5b89\u5168\u6027\u3001\u8010\u53d7\u6027\u548c\u80bf\u7624\u603b\u4f53\u53cd\u5e94\u7387\uff08ORR\uff09\u3002<\/span><\/span><\/p>\n

 <\/span><\/p>\n

3.  <\/span>\u8bd5\u9a8c\u8bbe\u8ba1<\/span><\/p>\n

\u8bd5\u9a8c\u5206\u7c7b\uff1a    \u5b89\u5168\u6027\u548c\u6709\u6548\u6027<\/span><\/p>\n

\u8bd5\u9a8c\u5206\u671f\uff1a    II\u671f<\/span><\/p>\n

\u8bbe\u8ba1\u7c7b\u578b\uff1a    \u5355\u81c2\u8bd5\u9a8c<\/span><\/p>\n

\u968f\u673a\u5316\uff1a      \u975e\u968f\u673a\u5316<\/span><\/p>\n

\u76f2\u6cd5\uff1a        \u5f00\u653e<\/span><\/p>\n

\u8bd5\u9a8c\u8303\u56f4\uff1a    \u56fd\u9645\u591a\u4e2d\u5fc3\u8bd5\u9a8c<\/span><\/p>\n

\u8bd5\u9a8c\u4eba\u6570\uff1a    \u603b\u4f53<\/span>126<\/span>\u4eba\uff0c\u4e2d\u56fd<\/span>66<\/span>\u4eba<\/span><\/span><\/p>\n

 <\/span><\/p>\n

4.  <\/span>\u5165\u9009\u6807\u51c6\uff08\u5fc5\u987b\u5168\u90e8\u7b26\u5408\uff09<\/span><\/p>\n

1  \u5728\u65e2\u5f80\u63a5\u53d7\u8fc7\u81f3\u5c11\u4e00\u79cd\u7cfb\u7edf\u6cbb\u7597\u65b9\u6848\u7684HBV+ HCC \u53d7\u8bd5\u8005\u4e2d\u8bc4\u4f30ATG-008 \u7684\u836f\u4ee3\u52a8\u529b\u5b66\uff08PK\uff09\u3001\u5b89\u5168\u6027\u3001\u8010\u53d7\u6027\u548c\u80bf\u7624\u603b\u4f53\u53cd\u5e94\u7387\uff08ORR\uff09\u3002<\/span><\/p>\n

2  \u6309\u7167\u5df4\u585e\u7f57\u90a3\u4e34\u5e8a\u809d\u764c\u5206\u671f\uff08BCLC\uff09\u786e\u5b9a\u4e3a\u65e0\u6cd5\u5207\u9664\u7684B\u671f\uff08\u4e2d\u671f\uff09\u6216C\u671f\uff08\u665a \u671f\uff09\u7684HCC\u3002\u5982\u679c\u662fB\u671f\uff0c\u53d7\u8bd5\u8005\u5fc5\u987b\u662f\u624b\u672f\u6216\u5c40\u90e8\u6cbb\u7597\u4e4b\u540e\u51fa\u73b0\u75be\u75c5\u8fdb\u5c55\uff0c\u6216\u8005\u4e0d\u9002\u5408\u63a5\u53d7\u624b\u672f\u6216\u5c40\u90e8\u6cbb\u7597<\/span><\/p>\n

3  HBV+\u88ab\u5b9a\u4e49\u4e3a\u6162\u6027HBV\u611f\u67d3\u6216\u6709HBV\u611f\u67d3\u75c5\u53f2\uff0c\u4f9d\u636e\u4efb\u4f55\u4ee5\u4e0b\u8840\u6e05\u5b66\u7ed3\u679c\uff1aHBcAb+\u3001HBsAg+\u3001HBV-DNA+ <\/span><\/p>\n

4  \u65e2\u5f80\u63a5\u53d7\u8fc7\u81f3\u5c11\u4e00\u79cd\u7cfb\u7edf\u6cbb\u7597\u65b9\u6848\uff08\u5728\u7d22\u62c9\u975e\u5c3c\u6cbb\u7597\u548c\/\u6216\u5316\u7597\u671f\u95f4\u6216\u4e4b\u540e\u7ecf\u5f71\u50cf\u5b66\u68c0\u67e5\u786e\u5b9a\u4e3a\u75be\u75c5\u8fdb\u5c55\uff09\u3002\u63a5\u53d7\u8fc7\u5176\u4ed6\uff08\u88ab\u5f53\u5730\u836f\u653f\u90e8\u95e8\u6240\u6279\u51c6\uff09\u6cbb\u7597\u5982\u745e\u683c\u975e\u5c3c\u548c\/\u6216\u6297PD-1\u6297\u4f53\u7b49\u7684\u53d7\u8bd5\u8005\u5982\u679c\u7b26\u5408\u6240\u6709\u5176\u4ed6\u5165\u9009\/\u6392\u9664\u6807\u51c6\uff0c\u53ef\u4ee5\u53c2\u4e0e\u7814\u7a76\u3002 a. \u5316\u7597\u5305\u62ecFOLFOX\uff08\u6c1f\u5c3f\u5627\u5576\u3001\u919b\u6c22\u53f6\u9178\u548c\u5965\u6c99\u5229\u94c2\uff09\u6216\u4efb\u4f55\u5176\u4ed6\u542b\u94c2\u65b9\u6848\u3002 b. \u5316\u7597\u22652\u4e2a\u7597\u7a0b<\/span><\/p>\n

5  ECOG\u4f53\u80fd\u72b6\u6001\u8bc4\u5206\u4e3a0\u5206\u62161\u5206<\/span><\/p>\n

6  \u8840\u751f\u5316\u68c0\u67e5\u7ed3\u679c\uff0c\u7b26\u5408\u5982\u4e0b\u7ed3\u679c\uff1a a. AST\uff08SGOT\uff09\u548cALT\uff08SGPT\uff09\u2264 5x\u6b63\u5e38\u4e0a\u9650\u503c\uff08ULN\uff09\u3002 b. \u603b\u80c6\u7ea2\u7d20\u2264 2x ULN c. \u808c\u9150\u2264 1.5 x ULN\u621624\u5c0f\u65f6\u6e05\u9664\u7387\u2265 50 mL\/min <\/span><\/p>\n

7  \u9aa8\u9ad3\u529f\u80fd\u5145\u5206\uff0c\u57fa\u4e8e\u5982\u4e0b\u7ed3\u679c\uff1a a. \u7edd\u5bf9\u4e2d\u6027\u7c92\u7ec6\u80de\u8ba1\u6570\uff08ANC\uff09\u2265 1.5x 109\u4e2a\u7ec6\u80de\/Lb. \u8840\u5c0f\u677f \u2265 75x 109\u4e2a\u7ec6\u80de\/L c. \u8840\u7ea2\u86cb\u767d\u2265 9 g\/dL <\/span><\/p>\n

8  Child-Pugh A\u7ea7\uff085\u5206\u62166\u5206\uff09\u800c\u65e0\u809d\u6027\u8111\u75c5\u3002<\/span><\/p>\n

9  \u7537\u6027\u53d7\u8bd5\u8005\uff08\u5305\u62ec\u5df2\u7ecf\u63a5\u53d7\u8fc7\u8f93\u7cbe\u7ba1\u7ed3\u624e\u672f\u8005\uff09\u5fc5\u987b\u540c\u610f\u5728\u4e0e\u80b2\u9f84\u5987\u5973\u7684\u6027\u751f\u6d3b\u4e2d\u4f7f\u7528\u907f\u5b55\u5957\u4e14\u81ea\u7b7e\u7f72ICF\u4e4b\u65e5\u8d77\u5728\u4f7f\u7528\u7814\u7a76\u836f\u7269\u671f\u95f4\u53ca\u6700\u540e\u4e00\u6b21\u63a5\u53d7\u7814\u7a76\u836f\u7269\u540e3\u4e2a\u6708\u5185\u65e0\u4f7f\u5973\u65b9\u6000\u5b55\u8ba1\u5212\u3002<\/span><\/p>\n

10  \u80b2\u9f84\u5973\u6027\u53d7\u8bd5\u8005\u5fc5\u987b\u6ee1\u8db3\u4ee5\u4e0b\u4e24\u4e2a\u6761\u4ef6\uff1a a. \u540c\u610f\u81ea\u7b7e\u7f72ICF\u4e4b\u65e5\u8d77\u5728\u4f7f\u7528\u7814\u7a76\u836f\u7269\u671f\u95f4\u53ca\u6700\u540e\u4e00\u6b64\u63a5\u53d7\u7814\u7a76\u836f\u7269\u540e28\u5929\u5185\u540c\u65f6\u4f7f\u7528\u4e24\u79cd\u7814\u7a76\u533b\u5e08\u8ba4\u53ef\u7684\u907f\u5b55\u65b9\u6cd5\u6216\u8005\u5b8c\u5168\u7981\u6b32\u3002 i. \u771f\u5b9e\u7981\u6b32\uff1a\u5f53\u6b64\u65b9\u6cd5\u4e0e\u53d7\u8bd5\u8005\u504f\u597d\u7684\u548c\u65e5\u5e38\u751f\u6d3b\u65b9\u5f0f\u76f8\u4e00\u81f4\u65f6\u3002\u5468\u671f\u7981\u6b32\uff08\u5982\u6839\u636e\u65e5\u5386\u3001\u6392\u5375\u3001\u75c7\u72b6\u4f53\u6e29\u3001\u6392\u5375\u540e\u65b9\u6cd5\uff09\u5e76\u505c\u7528\u662f\u4e0d\u88ab\u63a5\u53d7\u7684\u907f\u5b55\u65b9\u6cd5\u3002 ii. \u53ef\u63a5\u53d7\u7684\u907f\u5b55\u65b9\u6cd5\u5305\u62ec\uff1a\u53e3\u670d\u907f\u5b55\u836f\u3001\u6ce8\u5c04\u907f\u5b55\u836f\u6216\u8005\u690d\u5165\u6027\u6fc0\u7d20\u7c7b\u907f\u5b55\u836f\uff1b\u5bab\u5185\u8282\u80b2\u5668\uff1b\u5e26\u6709\u6740\u7cbe\u5242\u7684\u5c4f\u969c\u7c7b\u907f\u5b55\u5de5\u5177\uff1b\u6216\u8005\u4f34\u4fa3\u63a5\u53d7\u4e86\u7edd\u80b2\u624b\u672f\uff0c\u52a0\u4e4b\u4f7f\u7528\u81f3\u5c11\u4e00\u79cd\u5c4f\u969c\u7c7b\u907f\u5b55\u5de5\u5177\u3002b. \u7b5b\u9009\u65f6\u7684\u8840\u6e05\u598a\u5a20\u8bd5\u9a8c\u7ed3\u679c\u5448\u9634\u6027\uff0c\u5e76\u5f97\u5230\u9996\u6b21\u4f7f\u7528\u7814\u7a76\u836f\u7269\uff08IP\uff09\u524d72\u5c0f\u65f6\u5185\u5c3f\u6db2\u598a\u5a20\u8bd5\u9a8c\u9634\u6027\u7ed3\u679c\u7684\u8bc1\u5b9e\uff08\u5982\u679c\u8840\u6e05\u68c0\u67e5\u8ddd\u79bb\u9996\u6b21\u7528\u836f>72\u5c0f\u65f6\uff09\uff1b\u598a\u5a20\u8bd5\u9a8c\u7684\u7075\u654f\u5ea6\u81f3\u5c11\u4e3a25 mIU\/mL\u3002<\/span><\/p>\n

 <\/span><\/p>\n

5.  <\/span>\u6392\u9664\u6807\u51c6\uff08\u5fc5\u987b\u5168\u90e8\u4e0d\u7b26\u5408\uff09<\/span><\/p>\n

1  \u65e0\u6cd5\u8010\u53d7\u7d22\u62c9\u975e\u5c3c\/\u745e\u6208\u975e\u5c3c\uff0c\u4f8b\u5982\u53d7\u8bd5\u8005\u56e0\u6bd2\u6027\u800c\u5fc5\u987b\u505c\u836f\u3002<\/span><\/p>\n

2  \u6709\u75c7\u72b6\u7684\u4e2d\u67a2\u795e\u7ecf\u7cfb\u7edf\u8f6c\u79fb\u3002\u65e2\u5f80\u56e0\u8111\u90e8\u8f6c\u79fb\u800c\u63a5\u53d7\u8fc7\u6cbb\u7597\u4e14\u5728\u968f\u673a\u5316\u4e4b\u524d\u75c5\u60c5\u5df2\u7a33\u5b9a\u8fbe4\u5468\u7684\u60c5\u51b5\u662f\u5141\u8bb8\u7684\u3002<\/span><\/p>\n

3  \u5728\u7b5b\u9009\u524d14\u5929\u5185\u63a5\u53d7\u8fc7\u7d22\u62c9\u975e\u5c3c\/\u745e\u6208\u975e\u5c3c\u6cbb\u7597<\/span><\/p>\n

4  \u5728\u7b5b\u9009\u524d4\u5468\u5185\uff08\u62165\u4e2a\u534a\u8870\u671f\u5185\uff0c\u4ee5\u8f83\u77ed\u8005\u4e3a\u51c6\uff09\u63a5\u53d7\u8fc7HCC\u5c40\u90e8\u6cbb\u7597\uff08\u5982TACE\u3001RFA\uff09\u3001\u5168\u8eab\u5316\u7597\u3001\u6fc0\u7d20\u6cbb\u7597\uff08\u5982\u4ed6\u83ab\u6614\u82ac\uff09\u6216\u4e34\u5e8a\u8bd5\u9a8c\u836f\u7269\u6cbb\u7597\u3002<\/span><\/p>\n

5  HBV\u548c\u4e19\u578b\u809d\u708e\u75c5\u6bd2\uff08HCV\uff09\u68c0\u6d4b\u7ed3\u679c\u5747\u4e3a\u9633\u6027\u3002 a. HCV \u9633\u6027\u88ab\u5b9a\u4e49\u4e3a\u6297 HCV \u6216 HCV-RNA \u68c0\u6d4b\u7ed3\u679c\u5448\u9633\u6027\u3002<\/span><\/p>\n

6  \u9884\u671f\u5bff\u547d\u5c11\u4e8e3\u4e2a\u6708<\/span><\/p>\n

7  \u65e2\u5f80\u63a5\u53d7\u8fc7mTOR\uff08TORC1\u548c\/\u6216TORC2\uff09\u6291\u5236\u5242\u6cbb\u7597\uff0c\u5305\u62ec\u897f\u7f57\u83ab\u53f8\u3001\u5766\u7f57\u83ab\u53f8\u3001\u4f9d\u7ef4\u83ab\u53f8\u548c\u5176\u4ed6\u7684\u8bd5\u9a8c\u6027\u6216\u5df2\u83b7\u51c6\u7684mTOR\/PI3K\/AKT\u6291\u5236\u5242\u3002<\/span><\/p>\n

8  \u5728\u7b5b\u9009\u671f\u524d28\u5929\u5185\u63a5\u53d7\u8fc7\u5927\u624b\u672f\u6216\u53d1\u751f\u663e\u8457\u5916\u4f24\u3002<\/span><\/p>\n

9  \u5c1a\u672a\u4ece\u65e2\u5f80\u6240\u63a5\u53d7\u7684\u6297\u764c\u6cbb\u7597\u6240\u81f4\u6025\u6027\u6bd2\u6027\u6548\u5e94\u3001\u653e\u7597\u6216\u5927\u624b\u672f\/\u663e\u8457\u5916\u4f24\u4e2d\u6062\u590d\u8fc7\u6765\u3002<\/span><\/p>\n

10  \u5728\u7b5b\u9009\u671f\u524d7\u5929\u5185\u63a5\u53d7\u8fc7\u5c0f\u624b\u672f\uff08\u653e\u7f6e\u4e2d\u5fc3\/\u5916\u5468\u5bfc\u7ba1\u6216\u8fdb\u884c\u76ae\u80a4\u6d3b\u68c0\u9664\u5916\uff09\u3002<\/span><\/p>\n

11  \u6b63\u63a5\u53d7\u76ae\u8d28\u7c7b\u56fa\u9187\u6cbb\u7597\uff08\u6bcf\u65e5\u6cfc\u5c3c\u677e\u7b49\u6548\u5242\u91cf\u2265 10mg\uff09\u6216\u5176\u4ed6\u5168\u8eab\u514d\u75ab\u7cfb\u7edf\u8c03\u8282\u5242\u6301\u7eed\u6cbb\u7597\u3002<\/span><\/p>\n

12  \u63a7\u5236\u4e0d\u4f73\u7684\u7cd6\u5c3f\u75c5\uff0c\u5176\u5b9a\u4e49\u4e3aHbA1c >8%\u3002<\/span><\/p>\n

13  \u6709\u5668\u5b98\u79fb\u690d\u53f2\u3002<\/span><\/p>\n

14  \u7ecf\u6cbb\u7597\u4ecd\u7136\u6301\u7eed\u7684\u7f8e\u56fd\u56fd\u7acb\u764c\u75c7\u7814\u7a76\u6240\uff08NCI\uff09\u5e38\u89c1\u4e0d\u826f\u53cd\u5e94\u672f\u8bed\u8bc4\u5b9a\u6807\u51c6\uff08 CTCAE\uff0c4.03\u7248\uff09\u22652\u7ea7\u8179\u6cfb\u6216\u5438\u6536\u4e0d\u826f\uff0c\u6216\u8005\u4efb\u4f55\u53ef\u5f71\u54cd\u7814\u7a76\u836f\u7269\u5438\u6536\u7684\u663e\u8457\u80c3\u80a0\u9053\u75be\u75c5\u3002<\/span><\/p>\n

15  \u6709\u4e34\u5e8a\u610f\u4e49\u7684\u3001\u9700\u8981\u5728\u7b5b\u9009\u671f\u524d28\u5929\u5185\u8fdb\u884c\u533b\u5b66\u5e72\u9884\u7684\u51fa\u8840\uff0c\u5305\u62ec\u98df\u9053\u9759\u8109\u66f2\u5f20\u51fa\u8840\u3002<\/span><\/p>\n

16  \u5df2\u77e5\u6709\u4eba\u7c7b\u514d\u75ab\u7f3a\u9677\u75c5\u6bd2\uff08HIV\uff09\u611f\u67d3\u75c5\u53f2\u6216\u76ee\u524d\u88ab\u8bca\u65ad\u4e3a\u8be5\u75c5\uff0c\u4e0d\u7ba1\u6cbb\u7597\u60c5\u51b5\u5982\u4f55\u3002<\/span><\/p>\n

17  \u53d7\u8bd5\u8005\u540c\u65f6\u60a3\u6709\u9664\u809d\u764c\u5916\u5176\u4ed6\u7684\u6d3b\u52a8\u6027\u6076\u6027\u80bf\u7624\uff08\u975e\u9ed1\u8272\u7d20\u7624\u76ae\u80a4\u764c\u3001\u6fc0\u7d20\u6cbb\u7597\u8fc7\u7684\u975e\u8fdb\u5c55\u6027\u524d\u5217\u817a\u764c\u6216\u5bab\u9888\u539f\u4f4d\u764c\u9664\u5916\uff09\u3002\u82e5\u60a3\u8005\u7684\u7b2c\u4e8c\u79cd\u6076\u6027\u80bf\u7624\u5728\u672c\u7814\u7a76\u524d\u5df2\u6cbb\u6108>5\u5e74\u53ef\u8fdb\u5165\u8bd5\u9a8c\u3002<\/span><\/p>\n

18  \u63a7\u5236\u4e0d\u4f73\u7684\u95f4\u53d1\u6027\u75be\u75c5\uff0c\u5305\u62ec\u4f46\u4e0d\u9650\u4e8e\u9700\u8981\u6297\u751f\u7d20\u3001\u6297\u771f\u83cc\u836f\u7269\u6216\u6297\u75c5\u6bd2\u836f\u7269\u6cbb\u7597\uff08\u6297HBV\u6cbb\u7597\u9664\u5916\uff09\u7684\u8fdb\u884c\u6027\u6216\u6d3b\u52a8\u6027\u611f\u67d3\uff08\u5982\u7ed3\u6838\u75c5\uff09\u3001\u75c7\u72b6\u6027\u5fc3\u8870\u3001\u5fc3\u5f8b\u5931\u5e38 \u3001\u6025\u6027\u6216\u6162\u6027\u80f0\u817a\u708e\u6216\u8005\u4f1a\u9650\u5236\u9075\u5b88\u7814\u7a76\u8981\u6c42\u7684\u7cbe\u795e\u6027\u75be\u75c5\/\u793e\u4ea4\u969c\u788d\u3002<\/span><\/p>\n

19  \u53ef\u5bfc\u81f4\u53d7\u8bd5\u8005\u4e0d\u80fd\u5b8c\u5168\u9075\u5b88\u5b9e\u9a8c\u65b9\u6848\u7684\u663e\u8457\u533b\u5b66\u95ee\u9898\u3001\u5b9e\u9a8c\u5ba4\u68c0\u67e5\u5f02\u5e38\u6216\u8005\u7cbe\u795e\u75be\u75c5\u3002<\/span><\/p>\n

20  \u53d7\u8bd5\u8005\u82e5\u53c2\u4e0e\u7814\u7a76\u4f1a\u5bfc\u81f4\u51fa\u73b0\u65e0\u6cd5\u63a5\u53d7\u7684\u98ce\u9669\u7684\u4efb\u4f55\u60c5\u51b5\uff0c\u5305\u62ec\u5b58\u5728\u5b9e\u9a8c\u5ba4\u68c0\u67e5\u5f02\u5e38\u7684\u60c5\u51b5\u3002<\/span><\/p>\n

21  \u4efb\u4f55\u53ef\u5e72\u6270\u8bd5\u9a8c\u6570\u636e\u89e3\u8bfb\u7684\u60c5\u51b5\u3002<\/span><\/p>\n

 <\/span><\/p>\n

6.  \u7814\u7a76\u8005\u4fe1\u606f<\/span><\/p>\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n
\n

\u5e8f\u53f7 <\/span><\/p>\n<\/td>\n

\n

\u673a\u6784\u540d\u79f0 <\/span><\/p>\n<\/td>\n

\n

\u4e3b\u8981\u7814\u7a76\u8005 <\/span><\/p>\n<\/td>\n

\n

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\n

\u7701\uff08\u5dde\uff09 <\/span><\/p>\n<\/td>\n

\n

\u57ce\u5e02 <\/span><\/p>\n<\/td>\n<\/tr>\n

\n

1 <\/span><\/p>\n<\/td>\n

\n

\u4e2d\u56fd\u4eba\u6c11\u89e3\u653e\u519b\u7b2c\u516b\u4e00\u533b\u9662 <\/span><\/p>\n<\/td>\n

\n

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\n

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\n

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\n

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\n

2 <\/span><\/p>\n<\/td>\n

\n

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\n

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\n

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\n

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\n

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\n

3 <\/span><\/p>\n<\/td>\n

\n

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\n

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\n

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\n

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\n

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\n

4 <\/span><\/p>\n<\/td>\n

\n

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\n

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\n

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\n

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\n

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\n

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\n

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\n

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\n

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\n

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\n

6 <\/span><\/p>\n<\/td>\n

\n

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\n

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\n

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\n

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\n

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\n

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\n

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\n

8 <\/span><\/p>\n<\/td>\n

\n

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\n

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9 <\/span><\/p>\n<\/td>\n

\n

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\n

10 <\/span><\/p>\n<\/td>\n

\n

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\n

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11 <\/span><\/p>\n<\/td>\n

\n

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12 <\/span><\/p>\n<\/td>\n

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\n

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\n

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13 <\/span><\/p>\n<\/td>\n

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\n

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\n

14 <\/span><\/p>\n<\/td>\n

\n

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\n

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\n

15 <\/span><\/p>\n<\/td>\n

\n

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\n

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\n

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\n

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\n

16 <\/span><\/p>\n<\/td>\n

\n

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\n

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\n

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\n

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\n

17 <\/span><\/p>\n<\/td>\n

\n

\u4e2d\u56fd\u4eba\u6c11\u89e3\u653e\u519b\u6c88\u9633\u519b\u533a\u603b\u533b\u9662 <\/span><\/p>\n<\/td>\n

\n

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\n

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\n

\u8fbd\u5b81 <\/span><\/p>\n<\/td>\n

\n

\u6c88\u9633 <\/span><\/p>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

 <\/span><\/p>\n

\u672c\u8bd5\u9a8c\u4fe1\u606f\u6765\u81ea<\/span>CFDA<\/span>\u201c\u836f\u7269\u4e34\u5e8a\u8bd5\u9a8c\u767b\u8bb0\u4e0e\u516c\u793a\u5e73\u53f0\u201d\u3002<\/span><\/span><\/p>\n

\u6b22\u8fce\u7533\u529e\u65b9\/CRO\/\u533b\u9662\u63d0\u4f9b\u80bf\u7624\u62db\u52df\u4fe1\u606f\uff0c\u53ef\u4ee5\u53d1\u90ae\u4ef6\u81f3LCSYZMXX@163.com\uff0c\u672c\u516c\u4f17\u53f7\u514d\u8d39\u63a8\u9001\u3002<\/span><\/p>\n

 <\/span><\/p>\n


<\/p>\n

\n

\u59cb\u53d1\u4e8e\u5fae\u4fe1\u516c\u4f17\u53f7\uff1a \u4e34\u5e8a\u8bd5\u9a8c\u62db\u52df\u4fe1\u606f <\/p>\n<\/blockquote>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

1.  \u8bd5\u9a8c\u836f\u7269\u7b80\u4ecb ATG-008\u662fTORC1\/TORC2 \u53cc\u91cd\u6291\u5236\u5242\uff0c\u672c\u8bd5\u9a8c\u7684\u9002\u5e94\u75c7\u662f\u65e2\u5f80\u63a5\u53d7\u8fc7 […]<\/p>\n","protected":false},"author":1,"featured_media":30080,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[2],"tags":[],"_links":{"self":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/30079"}],"collection":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/comments?post=30079"}],"version-history":[{"count":1,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/30079\/revisions"}],"predecessor-version":[{"id":30085,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/30079\/revisions\/30085"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/media\/30080"}],"wp:attachment":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/media?parent=30079"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/categories?post=30079"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/tags?post=30079"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}