{"id":30157,"date":"2018-08-07T01:00:00","date_gmt":"2018-08-09T04:06:19","guid":{"rendered":"http:\/\/www.05921.net\/index.php\/2018\/08\/09\/2018%e4%b8%8a%e5%8d%8a%e5%b9%b4%e5%a4%a7%e5%8d%9620%e4%ba%bf%e7%be%8e%e5%85%83%ef%bc%81%e8%be%89%e7%91%9e%e4%b9%b3%e8%85%ba%e7%99%8c%e6%96%b0%e8%8d%afibrance%e6%ad%a3%e5%bc%8f%e7%99%bb%e9%99%86\/"},"modified":"2018-08-09T12:06:21","modified_gmt":"2018-08-09T04:06:21","slug":"2018%e4%b8%8a%e5%8d%8a%e5%b9%b4%e5%a4%a7%e5%8d%9620%e4%ba%bf%e7%be%8e%e5%85%83%ef%bc%81%e8%be%89%e7%91%9e%e4%b9%b3%e8%85%ba%e7%99%8c%e6%96%b0%e8%8d%afibrance%e6%ad%a3%e5%bc%8f%e7%99%bb%e9%99%86","status":"publish","type":"post","link":"https:\/\/www.05921.net\/index.php\/30157\/","title":{"rendered":"2018\u4e0a\u534a\u5e74\u5927\u535620\u4ebf\u7f8e\u5143\uff01\u8f89\u745e\u4e73\u817a\u764c\u65b0\u836fIbrance\u6b63\u5f0f\u767b\u9646\u4e2d\u56fd"},"content":{"rendered":"
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Ibrance<\/span>\u662f<\/span>first in class\u7684\u7ec6\u80de\u5468\u671f\u86cb\u767d\u4f9d\u8d56\u6027\u6fc0\u91764\/6<\/span>\uff08CDK4\/6<\/span>\uff09\u6291\u5236\u5242\uff0c<\/span>\u6700\u65e9\u57282015\u5e742\u67083\u65e5\u83b7\u5f97FDA\u52a0\u901f\u6279\u51c6\u4e0a\u5e02\u3002\u6839\u636e\u8d22\u62a5\u6570\u636e\uff0cIbrance\u7684<\/span>2017\u5e74\u9500\u552e\u989d\u5df2\u7ecf\u7a81\u783430\u4ebf\u7f8e\u5143\uff0c2018H1\u9500\u552e\u989d\u8fbe\u523019.6\u4ebf\u7f8e\u5143\uff0c\u540c\u6bd4\u589e\u957f28%\uff0c\u662f\u8f89\u745e\u500d\u53d7\u5173\u6ce8\u7684\u4e00\u4e2a\u660e\u661f\u91cd\u78c5\u70b8\u5f39\u65b0\u836f\u3002<\/span><\/p>\n


<\/span><\/p>\n

\u8f89\u745eIbrance\u5386\u5e74\u5168\u7403\u9500\u552e\u989d<\/span><\/span><\/p>\n

\"2018\u4e0a\u534a\u5e74\u5927\u535620\u4ebf\u7f8e\u5143\uff01\u8f89\u745e\u4e73\u817a\u764c\u65b0\u836fIbrance\u6b63\u5f0f\u767b\u9646\u4e2d\u56fd\"<\/p>\n


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2013 \u5e74FDA\u6388\u4e88Ibrance<\/span><\/span>\u6cbb\u7597\u665a\u671f\u4e73\u817a\u764c\u7684\u7a81\u7834\u6027\u836f\u7269\u8d44\u683c\uff0c2015 \u5e74FDA \u4ee5\u52a0\u901f\u6279\u51c6Ibrance<\/span><\/span>\u4e0a\u5e02<\/span>\uff0c\u7528\u4e8e\u6cbb\u7597\u665a\u671f\u4e73\u817a\u764c\u3002\u57fa\u4e8e\u6b64\u7a81\u7834\u6027\u8fdb\u5c55\uff0c\u7f8e\u56fd\u56fd\u7acb\u7efc\u5408\u764c\u75c7\u7f51\u7edc\uff08NCCN\uff09\u6307\u5357\u63a8\u8350Ibrance<\/span><\/span>\u8054\u5408\u82b3\u9999\u5316\u9176\u6291\u5236\u5242\u4f5c\u4e3aHR+\/ HER2-\u665a\u671f\u6216\u8f6c\u79fb\u6027\u4e73\u817a\u764c\u7684\u4e00\u7ebf\u6cbb\u7597\u65b9\u6848[3]\u3002<\/span><\/p>\n

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<\/span><\/p>\n

\u53c2\u8003\u8d44\u6599<\/span><\/p>\n

[1]\u4e2d\u56fd\u764c\u75c7\u7edf\u8ba12015<\/span><\/p>\n

[2]\u5f90\u5175\u6cb3\u7b49.\u4e2d\u56fd\u665a\u671f\u4e73\u817a\u764c\u7ef4\u6301\u6cbb\u7597\u4e13\u5bb6\u5171\u8bc6.\u4e2d\u534e\u533b\u5b66\u6742\u5fd7.2018;98(2):87-90<\/span><\/p>\n

[3] NCCN Clinical Practice Guidelines in Oncology\uff08NCCN Guidelines\u00ae\uff09 for Brest Cancer V1 2018<\/span><\/p>\n

[4] IBRANCE\u00ae (palbociclib) PrescribingInformation. New York. NY: Pfizer Inc: 2018.<\/span><\/p>\n


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