{"id":30859,"date":"2018-08-04T01:00:00","date_gmt":"2018-08-09T04:12:04","guid":{"rendered":"http:\/\/www.05921.net\/index.php\/2018\/08\/09\/%e3%80%90boa%e5%b9%b2%e8%b4%a7%e5%9b%9e%e9%a1%be%e3%80%91%e8%82%bf%e7%98%a4%e7%95%8c%e5%a4%a7%e5%92%96%e5%85%b1%e8%af%9d%e7%b2%be%e5%87%86%e5%8c%bb%e5%ad%a6%e6%96%b0%e9%a3%8e%e5%90%91\/"},"modified":"2018-08-09T12:12:07","modified_gmt":"2018-08-09T04:12:07","slug":"%e3%80%90boa%e5%b9%b2%e8%b4%a7%e5%9b%9e%e9%a1%be%e3%80%91%e8%82%bf%e7%98%a4%e7%95%8c%e5%a4%a7%e5%92%96%e5%85%b1%e8%af%9d%e7%b2%be%e5%87%86%e5%8c%bb%e5%ad%a6%e6%96%b0%e9%a3%8e%e5%90%91","status":"publish","type":"post","link":"https:\/\/www.05921.net\/index.php\/30859\/","title":{"rendered":"\u3010BOA\u5e72\u8d27\u56de\u987e\u3011\u80bf\u7624\u754c\u5927\u5496\u5171\u8bdd\u7cbe\u51c6\u533b\u5b66\u65b0\u98ce\u5411"},"content":{"rendered":"<div class=\"bpp-post-content\">\n<p><img class=\"\"       style=\"\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/08\/beepress1-1533787925.jpeg\" alt=\"\u3010BOA\u5e72\u8d27\u56de\u987e\u3011\u80bf\u7624\u754c\u5927\u5496\u5171\u8bdd\u7cbe\u51c6\u533b\u5b66\u65b0\u98ce\u5411\" title=\"\u3010BOA\u5e72\u8d27\u56de\u987e\u3011\u80bf\u7624\u754c\u5927\u5496\u5171\u8bdd\u7cbe\u51c6\u533b\u5b66\u65b0\u98ce\u5411\"  \/><\/p>\n<section class=\"\" style=\"padding-left: 5px;max-width: 100%;letter-spacing: 0.5440000295639038px;text-align: justify;white-space: normal;font-size: 12px;color: rgb(152, 152, 162);line-height: 16px;border-left-width: 4px;border-left-style: solid;border-left-color: rgb(205, 0, 112);font-family: sans-serif;box-sizing: border-box !important;word-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\">\u6765\u6e90\uff1a\u80bf\u7624\u8d44\u8baf<br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  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border-box !important;word-wrap: break-word !important;\"  \/>\u4e2d\u56fd\u6297\u764c\u534f\u4f1a\u80bf\u7624\u7cbe\u51c6\u6cbb\u7597\u4e13\u59d4\u4f1a\u5019\u4efb\u4e3b\u4efb\u59d4\u5458\u7b49\u804c\u52a1<br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/>\u4e00\u76f4\u81f4\u529b\u4e8e\u6d88\u5316\u7cfb\u7edf\u80bf\u7624\u7cbe\u51c6\u836f\u7269\u6cbb\u7597\u3001\u6297\u80bf\u7624\u65b0\u836f\u7684I-IV\u671f\u4e34\u5e8a\u8bd5\u9a8c\u4e0e\u57fa\u7840\u8f6c\u5316\u7814\u7a76\uff0c\u62c5\u4efb\u79d1\u6280\u90e8\u56fd\u5bb6\u91cd\u70b9\u7814\u53d1\u8ba1\u5212\u201c\u80c3\u764c\u9776\u5411\u6cbb\u7597\u65b0\u6280\u672f\u7814\u7a76\u201d\u9879\u76ee\u9996\u5e2d\u4e13\u5bb6\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<p style=\"margin-top: 20px;margin-bottom: 20px;max-width: 100%;word-wrap: break-word;min-height: 1em;letter-spacing: 0.5440000295639038px;text-align: justify;white-space: normal;font-size: 16px;color: rgb(69, 69, 86);line-height: 26px;font-family: sans-serif;box-sizing: border-box !important;\"><span style=\"max-width: 100%;font-weight: 700;box-sizing: border-box !important;word-wrap: break-word !important;\">\u6c88\u7433\u6559\u6388\uff1a<\/span>\u8fd1\u5e74\u6765\uff0c\u80bf\u7624\u514d\u75ab\u6cbb\u7597\u53d1\u5c55\u8fc5\u731b\u3002\u5bf9\u4e8e\u514d\u75ab\u6cbb\u7597\u654f\u611f\u7684\u80bf\u7624\uff0c\u5168\u5916\u663e\u5b50\u7ec4\u68c0\u6d4b\uff08WES\uff09\u7684\u9700\u6c42\u5e76\u4e0d\u5341\u5206\u5f3a\u70c8\uff0c\u4f46\u5bf9\u4e8e\u80c3\u80a0\u80bf\u7624\u7b49\u5bf9\u514d\u75ab\u6cbb\u7597\u654f\u611f\u6027\u7a0d\u5dee\u7684\u764c\u79cd\uff0c\u8fd9\u65b9\u9762\u7684\u7814\u7a76\u663e\u5f97\u5c24\u4e3a\u8feb\u5207\u3002\u5728\u80c3\u80a0\u80bf\u7624\u4e2d\uff0c\u5bf9\u514d\u75ab\u6cbb\u7597\u654f\u611f\u4eba\u7fa4\u7684\u9009\u62e9\u8981\u6c42\u975e\u5e38\u9ad8\u3002<span style=\"max-width: 100%;font-weight: 700;box-sizing: border-box !important;word-wrap: break-word 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class=\"\" style=\"margin-top: 20px;margin-bottom: 20px;padding: 5px;max-width: 100%;caret-color: rgb(51, 51, 51);color: rgb(51, 51, 51);letter-spacing: 0.5440000295639038px;text-align: justify;white-space: normal;background-color: rgb(205, 0, 112);font-family: sans-serif;font-size: 16px;box-sizing: border-box !important;word-wrap: break-word !important;\">\n<section class=\"\" style=\"padding: 10px;max-width: 100%;border: 2px solid rgb(255, 255, 255);color: rgb(255, 255, 255);line-height: 24px;box-sizing: border-box !important;word-wrap: break-word !important;\">\n<p style=\"max-width: 100%;word-wrap: break-word;min-height: 1em;line-height: 24px;box-sizing: border-box !important;\"><span style=\"max-width: 100%;font-weight: 700;box-sizing: border-box !important;word-wrap: break-word !important;\">\u76ee\u524d\u8ba4\u4e3a\uff0c\u80bf\u7624\u7a81\u53d8\u8d1f\u8377\uff08TMB\uff09\u80fd\u5f88\u597d\u7684\u9884\u6d4b\u514d\u75ab\u6cbb\u7597\u53cd\u5e94\uff0c\u5176\u4e2d\u8840\u6db2\u80bf\u7624\u7a81\u53d8\u8d1f\u8377\uff08bTMB\uff09\u66f4\u662f\u5f53\u524d\u7684\u70ed\u70b9\u3002\u8bf7\u60a8\u8c08\u8c08TMB\u53cabTMB\u5728\u80bf\u7624\u514d\u75ab\u6cbb\u7597\u4e2d\u7684\u610f\u4e49\uff1f<\/span><\/p>\n<\/section>\n<\/section>\n<section class=\"\" style=\"margin-top: 20px;margin-bottom: 20px;max-width: 100%;letter-spacing: 0.5440000295639038px;text-align: justify;white-space: normal;font-size: 16px;line-height: 24px;color: rgb(205, 0, 112);font-weight: 700;display: -webkit-box;flex-flow: row;font-family: sans-serif;box-sizing: border-box !important;word-wrap: break-word !important;\">\n<section class=\"\" style=\"margin-right: 4px;max-width: 100%;height: 24px;box-sizing: border-box !important;word-wrap: break-word !important;\">\n<section class=\"\" style=\"margin-top: 4px;max-width: 100%;float: left;border-left-width: 8px;border-left-style: solid;border-left-color: rgb(205, 0, 112);border-top-width: 8px;border-top-style: solid;border-top-color: transparent;border-bottom-width: 8px;border-bottom-style: solid;border-bottom-color: transparent;opacity: 0.6;box-sizing: border-box !important;word-wrap: break-word !important;\"><\/section>\n<section class=\"\" style=\"margin-top: 4px;max-width: 100%;float: left;border-left-width: 8px;border-left-style: solid;border-left-color: rgb(205, 0, 112);border-top-width: 8px;border-top-style: solid;border-top-color: transparent;border-bottom-width: 8px;border-bottom-style: solid;border-bottom-color: transparent;box-sizing: border-box !important;word-wrap: break-word !important;\"><\/section>\n<\/section>\n<section class=\"\" style=\"max-width: 100%;-webkit-box-flex: 1;box-sizing: border-box !important;word-wrap: break-word !important;\">\n<p style=\"max-width: 100%;word-wrap: break-word;min-height: 1em;line-height: 24px;box-sizing: border-box !important;\">TMB\u5728\u514d\u75ab\u6cbb\u7597\u4e2d\u7684\u610f\u4e49<\/p>\n<\/section>\n<\/section>\n<p style=\"margin-top: 20px;margin-bottom: 20px;max-width: 100%;word-wrap: break-word;min-height: 1em;letter-spacing: 0.5440000295639038px;text-align: justify;white-space: normal;font-size: 16px;color: rgb(69, 69, 86);line-height: 26px;font-family: sans-serif;box-sizing: border-box !important;\"><span style=\"max-width: 100%;font-weight: 700;box-sizing: border-box !important;word-wrap: break-word !important;\">\u6c88\u7433\u6559\u6388\uff1a<\/span><span style=\"max-width: 100%;font-weight: 700;box-sizing: border-box !important;word-wrap: break-word !important;\">\u5927\u91cf\u7814\u7a76\u6570\u636e\u663e\u793aTMB\u53ef\u4ee5\u4f5c\u4e3a\u751f\u7269\u6807\u5fd7\u7269\u9884\u6d4b\u514d\u75ab\u6cbb\u7597\u7684\u7597\u6548<\/span>\uff0cTMB\u9ad8\u7684\u60a3\u8005\u6709\u53ef\u80fd\u5f62\u6210\u65b0\u6297\u539f\uff0c\u800c\u65b0\u6297\u539f\u7684\u5f62\u6210\u4e0ePD-1\/PD-L1\u7684\u7597\u6548\u662f\u660e\u786e\u76f8\u5173\u7684\u3002\u6240\u4ee5\uff0cTMB\u662f\u76ee\u524d\u514d\u75ab\u6cbb\u7597\u4e2d\u7684\u91cd\u8981\u6307\u6807\uff0c\u4e34\u5e8a\u5b9e\u8df5\u53d1\u73b0\uff0c\u5bf9\u4e8eMSI-H\u7684\u60a3\u8005\uff0c\u5176TMB\u57fa\u672c\u4e0a\u90fd\u5927\u4e8e10\uff08mut\/mb\uff09\uff0c\u8fd9\u7c7b\u60a3\u8005\u4f7f\u7528\u514d\u75ab\u6cbb\u7597\u662f\u6709\u6548\u7684\u3002\u540c\u65f6\uff0c\u6211\u4eec\u8fd8\u53d1\u73b0\u5982<span class=\"\" style=\"max-width: 100%;font-style: italic;box-sizing: border-box !important;word-wrap: break-word !important;\">POLE\u3001POLD1<\/span>\u7a81\u53d8\u7684\u4eba\u7fa4\uff0c\u5176TMB\u8981\u8fdc\u9ad8\u4e8eMSI-H\u7684\u60a3\u8005\uff0c\u800c\u8fd9\u90e8\u5206\u60a3\u8005\u5bf9\u514d\u75ab\u6cbb\u7597\u7684\u54cd\u5e94\u4e5f\u8f83\u597d\u3002\u56e0\u6b64\uff0c<span style=\"max-width: 100%;font-weight: 700;box-sizing: border-box !important;word-wrap: break-word !important;\">TMB\u9ad8\u7684\u80c3\u80a0\u9053\u80bf\u7624\u60a3\u8005\u4e5f\u5f88\u6709\u53ef\u80fd\u662f\u514d\u75ab\u6cbb\u7597\u7684\u83b7\u76ca\u4eba\u7fa4<\/span>\uff0c\u8fd9\u5728\u5176\u4ed6\u5b9e\u4f53\u7624\u4e2d\u5df2\u5f97\u5230\u8bc1\u5b9e\uff0c\u4f46\u5728\u80c3\u80a0\u9053\u80bf\u7624\u4ecd\u9700\u66f4\u591a\u7684\u4e34\u5e8a\u7814\u7a76\u6765\u652f\u6301\u3002<br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/p>\n<p style=\"margin-top: 20px;margin-bottom: 20px;max-width: 100%;word-wrap: break-word;min-height: 1em;letter-spacing: 0.5440000295639038px;text-align: justify;white-space: normal;font-size: 16px;color: rgb(69, 69, 86);line-height: 26px;font-family: sans-serif;box-sizing: border-box !important;\">TMB\u7684cut-off\u503c\u5982\u4f55\u754c\u5b9a\uff0c\u662f\u5426\u5982\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u768410\uff08mut\/mb\uff09\u5c31\u8db3\u591f\uff1f\u6211\u8ba4\u4e3a\u4e0d\u4e00\u5b9a\u3002\u53e6\u5916\uff0cTMB\u7684\u9ad8\u4f4e\u662f\u68c0\u6d4b\u591a\u5c11\u4e2a\u57fa\u56e0\u5f97\u5230\u7684\uff1f\u56fd\u9645\u4e0a\u6709\u6587\u7ae0\u62a5\u9053\u5728\u8fdb\u884c\u51e0\u5341\u4e07\u4e2a\u57fa\u56e0\u68c0\u6d4b\u65f6\u53d1\u73b0\uff0c\u80c3\u764c\u662f\u4e00\u4e2aTMB\u975e\u5e38\u9ad8\u7684\u7624\u79cd\uff0c\u4f46\u5728\u4e34\u5e8a\u5b9e\u8df5\u4e2d\u4f7f\u7528panel\u8fdb\u884c\u68c0\u6d4b\u65f6TMB\u5e76\u6ca1\u6709\u90a3\u4e48\u9ad8\u3002\u56e0\u6b64\uff0c\u4e34\u5e8a\u68c0\u6d4b\u7684\u57fa\u56e0\u6570\u91cf\u662f\u5426\u8db3\u591f\uff0c\u503c\u5f97\u6211\u4eec\u601d\u8003\u3002\u80c3\u764c\u4f5c\u4e3a\u4e2d\u56fd\u7684\u9ad8\u53d1\u80bf\u7624\uff0c\u5176\u590d\u6742\u6027\u8fdc\u8fdc\u8d85\u8fc7\u5176\u4ed6\u80bf\u7624\uff0c\u6240\u4ee5\u8fd9\u4e00\u9886\u57df\u4ecd\u9700\u8981\u79ef\u7d2f\u7ecf\u9a8c\u3002\u5982\u679c\u56fd\u5185\u7684\u57fa\u56e0\u68c0\u6d4b\u516c\u53f8\u80fd\u591f\u79ef\u7d2f\u66f4\u5927\u7684\u6837\u672c\u91cf\u57fa\u56e0\u8c31\uff0c\u90a3\u4e48\u6211\u4eec\u80fd\u771f\u6b63\u6d4b\u7b97\u4e2d\u56fd\u60a3\u8005\u4e2d\u524d10%\/15%\/20%\u4eba\u7fa4\u7684TMB\u8868\u8fbe\u60c5\u51b5\u4ee5\u53ca\u5bf9\u514d\u75ab\u6cbb\u7597\u7684\u54cd\u5e94\u72b6\u6001\uff0c\u8fd9\u662f\u5f88\u6709\u610f\u4e49\u7684\u3002<\/p>\n<section class=\"\" style=\"max-width: 100%;caret-color: rgb(51, 51, 51);color: rgb(51, 51, 51);letter-spacing: 0.5440000295639038px;text-align: justify;white-space: normal;font-family: sans-serif;font-size: 16px;box-sizing: border-box !important;word-wrap: break-word !important;\">\n<section class=\"\" style=\"margin-top: 20px;margin-bottom: 10px;padding-top: 20px;padding-bottom: 20px;max-width: 100%;display: -webkit-box;flex-flow: row;border-top-width: 1px;border-top-style: dashed;border-top-color: rgb(204, 0, 111);border-bottom-width: 1px;border-bottom-style: dashed;border-bottom-color: rgb(204, 0, 111);box-sizing: border-box !important;word-wrap: break-word !important;\">\n<section class=\"\" style=\"margin-right: 10px;max-width: 100%;width: 90px;height: 120px;background-color: rgb(214, 214, 221);border-top-left-radius: 2px;border-top-right-radius: 2px;border-bottom-right-radius: 2px;border-bottom-left-radius: 2px;overflow: hidden;box-sizing: border-box !important;word-wrap: break-word !important;\"><img class=\"\"     style=\"display: block;overflow: hidden;box-sizing: border-box !important;word-wrap: break-word !important;width: 90px !important;visibility: visible !important;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/08\/beepress5-1533787925.jpeg\" alt=\"\u3010BOA\u5e72\u8d27\u56de\u987e\u3011\u80bf\u7624\u754c\u5927\u5496\u5171\u8bdd\u7cbe\u51c6\u533b\u5b66\u65b0\u98ce\u5411\" title=\"\u3010BOA\u5e72\u8d27\u56de\u987e\u3011\u80bf\u7624\u754c\u5927\u5496\u5171\u8bdd\u7cbe\u51c6\u533b\u5b66\u65b0\u98ce\u5411\"  \/>&nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp;<\/section>\n<section class=\"\" style=\"max-width: 100%;-webkit-box-flex: 1;box-sizing: border-box !important;word-wrap: break-word !important;\">\n<section class=\"\" style=\"margin-right: 5px;max-width: 100%;display: inline-block;font-size: 17px;font-weight: 700;color: rgb(69, 69, 86);box-sizing: border-box !important;word-wrap: break-word !important;\">\u6881\u519b<\/section>\n<section class=\"\" style=\"max-width: 100%;display: inline-block;font-size: 15px;color: rgb(111, 111, 122);box-sizing: border-box !important;word-wrap: break-word !important;\">\u4e3b\u4efb\u533b\u5e08\uff0c\u535a\u58eb\u7814\u7a76\u751f\u5bfc\u5e08<\/section>\n<section class=\"\" style=\"margin-top: 10px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\">\n<p style=\"max-width: 100%;word-wrap: break-word;min-height: 1em;font-size: 12px;color: rgb(204, 0, 111);line-height: 18px;box-sizing: border-box !important;\">\u5317\u4eac\u5927\u5b66\u56fd\u9645\u533b\u9662 \u526f\u9662\u957f<br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/>\u5317\u4eac\u5927\u5b66\u56fd\u9645\u533b\u9662 \u80bf\u7624\u4e2d\u5fc3\u4e3b\u4efb<br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/>\u5317\u4eac\u5927\u5b66\u80bf\u7624\u533b\u9662 \u5927\u5185\u79d1\u526f\u4e3b\u4efb<br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/>\u517c\u4efb\u4e2d\u56fd\u4e34\u5e8a\u80bf\u7624\u5b66\u4f1a\uff08CSCO\uff09\u526f\u7406\u4e8b\u957f\u3001\u4e2d\u56fd\u6297\u764c\u534f\u4f1a\u80bf\u7624\u59d1\u606f\u548c\u5eb7\u590d\u4e13\u4e1a\u59d4\u5458\u4f1a\uff08CRPC\uff09\u526f\u4e3b\u4efb\u59d4\u5458\u3001\u4e2d\u56fd\u4e34\u5e8a\u80bf\u7624\u5b66\u4f1a\u809d\u764c\u4e13\u5bb6\u59d4\u5458\u4f1a\u526f\u4e3b\u4efb\u59d4\u5458\u3001\u4e2d\u56fd\u533b\u5e08\u534f\u4f1a\u7ed3\u76f4\u80a0\u80bf\u7624\u4e13\u4e1a\u59d4\u5458\u4f1a\u526f\u4e3b\u4efb\u59d4\u5458\u7b49\u804c\u52a1\u3002\u4efb\u300a\u4e2d\u56fd\u80bf\u7624\u4e34\u5e8a\u300b\u7f16\u59d4\u3001\u300a\u4e34\u5e8a\u80bf\u7624\u5b66\u6742\u5fd7\u300b\u7f16\u59d4\u3001\u300a\u4e2d\u534e\u80bf\u7624\u9632\u6cbb\u6742\u5fd7\u300b\u7f16\u59d4\u3001\u300aThe oncologist\u300b\u7f16\u59d4\u3001\u300a\u5b9e\u7528\u80bf\u7624\u6742\u5fd7\u300b\u7b49\u591a\u90e8\u6742\u5fd7\u7f16\u59d4<\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<p style=\"margin-top: 20px;margin-bottom: 20px;max-width: 100%;word-wrap: break-word;min-height: 1em;letter-spacing: 0.5440000295639038px;text-align: justify;white-space: normal;font-size: 16px;color: rgb(69, 69, 86);line-height: 26px;font-family: sans-serif;box-sizing: border-box !important;\"><span style=\"max-width: 100%;font-weight: 700;box-sizing: border-box !important;word-wrap: break-word !important;\">\u6881\u519b\u6559\u6388\uff1a<\/span>\u5728\u514d\u75ab\u6cbb\u7597\u5982\u706b\u5982\u837c\u7684\u53d1\u5c55\u8fc7\u7a0b\u4e2d\uff0c\u6211\u4eec\u65e2\u770b\u5230\u5f88\u597d\u7684\u7597\u6548\uff0c\u4e5f\u53d1\u73b0\u8bb8\u591a\u4e9f\u9700\u89e3\u51b3\u7684\u65b0\u95ee\u9898\uff0c\u5982\u514d\u75ab\u6cbb\u7597\u7684\u83b7\u76ca\u4eba\u7fa4\u3001\u514d\u75ab\u6cbb\u7597\u7684\u7597\u6548\u8bc4\u4ef7\u3001\u514d\u75ab\u6cbb\u7597\u8054\u5408\u5176\u4ed6\u6cbb\u7597\u6a21\u5f0f\uff08\u9776\u5411\u6cbb\u7597\u3001\u5316\u7597\uff09\u7b49\u3002\u5176\u4e2d\uff0c\u8981\u786e\u5b9a\u514d\u75ab\u6cbb\u7597\u7684\u83b7\u76ca\u4eba\u7fa4\u5c31\u9700\u8981\u660e\u786e\u76f8\u5173\u7684biomarker\uff0c\u5982PD-1\u7684\u8868\u8fbe\u4e0e\u5426\u4ee5\u53ca\u6570\u503c\u9ad8\u4f4e\u3001\u514d\u75ab\u8bc4\u5206(CPS\uff0c\u8054\u5408\u9633\u6027\u8bc4\u5206)\u548c\u80bf\u7624\u7a81\u53d8\u8d1f\u8377\uff08TMB\uff09\u90fd\u662f\u76ee\u524d\u7814\u7a76\u706b\u70ed\u7684biomarker\u3002<\/p>\n<p style=\"margin-top: 20px;margin-bottom: 20px;max-width: 100%;word-wrap: break-word;min-height: 1em;letter-spacing: 0.5440000295639038px;text-align: justify;white-space: normal;font-size: 16px;color: rgb(69, 69, 86);line-height: 26px;font-family: sans-serif;box-sizing: border-box !important;\">\u5bf9\u4e8eTMB\uff0c\u57fa\u4e8e\u80a0\u764c\u7684\u7814\u7a76\u53d1\u73b0\uff0cMSI-H\u7684\u60a3\u8005\uff0c\u5176TMB\u8d8a\u5927\uff0c\u5bf9\u514d\u75ab\u6cbb\u7597\u7684\u54cd\u5e94\u8d8a\u597d\u3002\u8fd9\u4e00\u53d1\u73b0\u5df2\u6269\u5c55\u5230\u5176\u4ed6\u80bf\u7624\uff0c\u5982\u6700\u8fd1\u5728\u80c3\u764c\u7684\u7814\u7a76\u4e0a\u4e5f\u89c2\u5bdf\u5230TMB\u8d8a\u5927\uff0c\u514d\u75ab\u6cbb\u7597\u7684\u7597\u6548\u8d8a\u597d\u3002\u56e0\u6b64\uff0c<span style=\"max-width: 100%;font-weight: 700;box-sizing: border-box !important;word-wrap: break-word !important;\">TMB\u8fd9\u4e00\u6307\u6807\u7ecf\u8fc7\u591a\u4e2a\u91cd\u8981\u4e34\u5e8a\u7814\u7a76\u7684\u8003\u9a8c\uff0c\u5f88\u53ef\u80fd\u662f\u975e\u5e38\u597d\u7684\u514d\u75ab\u6cbb\u7597biomarker\uff0c\u672a\u6765\u4ecd\u9700\u8fdb\u4e00\u6b65\u6269\u5927\u7814\u7a76\u4ee5\u8bc1\u5b9e\u5176\u79d1\u5b66\u6027\u4e0e\u51c6\u786e\u6027\u3002<\/span>\u5f53\u7136\uff0c\u6211\u8ba4\u4e3a\u514d\u75ab\u6cbb\u7597\u7684\u7597\u6548\u9884\u6d4b\u53ef\u80fd\u9700\u8981\u7efc\u5408\u7684\u6307\u6570\u6765\u8bc4\u5224\uff0c\u800c\u4e0d\u4ec5\u4ec5\u5355\u9760TMB\u4e00\u4e2a\u6307\u6807\uff0c\u4f8b\u5982\u7ed3\u5408PD-1\u7684\u8868\u8fbe\u3001CPS\u7b49\uff0c\u8fd9\u9700\u8981\u8fdb\u4e00\u6b65\u7684\u4e34\u5e8a\u7814\u7a76\u4e0e\u63a2\u7d22\u3002<\/p>\n<section class=\"\" style=\"margin-top: 20px;margin-bottom: 20px;max-width: 100%;letter-spacing: 0.5440000295639038px;text-align: justify;white-space: normal;font-size: 16px;line-height: 24px;color: rgb(205, 0, 112);font-weight: 700;display: -webkit-box;flex-flow: row;font-family: sans-serif;box-sizing: border-box !important;word-wrap: break-word !important;\">\n<section class=\"\" style=\"margin-right: 4px;max-width: 100%;height: 24px;box-sizing: border-box !important;word-wrap: break-word !important;\">\n<section class=\"\" style=\"margin-top: 4px;max-width: 100%;float: left;border-left-width: 8px;border-left-style: solid;border-left-color: rgb(205, 0, 112);border-top-width: 8px;border-top-style: solid;border-top-color: transparent;border-bottom-width: 8px;border-bottom-style: solid;border-bottom-color: transparent;opacity: 0.6;box-sizing: border-box !important;word-wrap: break-word !important;\"><\/section>\n<section class=\"\" style=\"margin-top: 4px;max-width: 100%;float: left;border-left-width: 8px;border-left-style: solid;border-left-color: rgb(205, 0, 112);border-top-width: 8px;border-top-style: solid;border-top-color: transparent;border-bottom-width: 8px;border-bottom-style: solid;border-bottom-color: transparent;box-sizing: border-box !important;word-wrap: break-word !important;\"><\/section>\n<\/section>\n<section class=\"\" style=\"max-width: 100%;-webkit-box-flex: 1;box-sizing: border-box !important;word-wrap: break-word !important;\">\n<p style=\"max-width: 100%;word-wrap: break-word;min-height: 1em;line-height: 24px;box-sizing: border-box !important;\">bTMB\u5728\u80bf\u7624\u514d\u75ab\u6cbb\u7597\u4e2d\u7684\u610f\u4e49<\/p>\n<\/section>\n<\/section>\n<p style=\"margin-top: 20px;margin-bottom: 20px;max-width: 100%;word-wrap: break-word;min-height: 1em;letter-spacing: 0.5440000295639038px;text-align: justify;white-space: normal;font-size: 16px;color: rgb(69, 69, 86);line-height: 26px;font-family: sans-serif;box-sizing: border-box !important;\"><span style=\"max-width: 100%;font-weight: 700;box-sizing: border-box !important;word-wrap: break-word !important;\">\u6c88\u7433\u6559\u6388\uff1a<\/span>\u4f17\u6240\u5468\u77e5\uff0c\u6db2\u4f53\u6d3b\u68c0\u7684\u53ef\u83b7\u5f97\u6027\u6bd4\u7ec4\u7ec7\u6d3b\u68c0\u8981\u597d\uff0c\u4e14\u521b\u4f24\u5c0f\u3001\u53ef\u52a8\u6001\u76d1\u6d4b\u3002\u4f46\u5229\u7528\u8840\u6db2\u4e2d\u7684ctDNA\u6765\u68c0\u6d4bTMB\uff0c\u867d\u7136\u5176\u7ed3\u679c\u76ee\u524d\u4e5f\u8bb8\u8fd8\u4e0d\u80fd\u4e0e\u7ec4\u7ec7\u6837\u672c\u7684\u7ed3\u679c\u76f8\u6bd4\uff0c\u4f46\u662fbTMB\u662f\u4e00\u4e2a\u975e\u5e38\u597d\u7684\u65b9\u5411\uff0c\u672a\u6765\u5e94\u79ef\u7d2f\u66f4\u591a\u6807\u672c\uff0c\u4e0e\u60a3\u8005\u6700\u7ec8\u7684\u6cbb\u7597\u6548\u679c\u8fdb\u884c\u5339\u914d\u6027\u5206\u6790\uff0c\u4ee5\u5f97\u5230\u4e00\u4e2a\u65b0\u7684\u3001\u66f4\u597d\u7684biomarker\u3002\u6cdb\u751f\u5b50\u516c\u53f8\u5728\u8fd9\u65b9\u9762\u7684\u5de5\u4f5c\u8d70\u5728\u4e86\u524d\u5217\uff0c\u5e0c\u671b\u80fd\u5c3d\u65e9\u770b\u5230\u6709\u610f\u4e49\u7684\u7814\u7a76\u7ed3\u679c\u3002<\/p>\n<p style=\"margin-top: 20px;margin-bottom: 20px;max-width: 100%;word-wrap: break-word;min-height: 1em;letter-spacing: 0.5440000295639038px;text-align: justify;white-space: normal;font-size: 16px;color: rgb(69, 69, 86);line-height: 26px;font-family: sans-serif;box-sizing: border-box !important;\"><span style=\"max-width: 100%;font-weight: 700;box-sizing: border-box !important;word-wrap: break-word !important;\">\u6881\u519b\u6559\u6388\uff1a<\/span>\u968f\u7740\u57fa\u56e0\u68c0\u6d4b\u6280\u672f\u7684\u53d1\u5c55\uff0c\u6211\u4eec\u80fd\u4ece\u8840\u6db2\u7684\u4e8c\u4ee3\u6d4b\u5e8f\uff08NGS\u68c0\u6d4b\uff09\u4e2d\u53d1\u73b0\u9057\u4f20\u4fe1\u606f\u7684\u91cd\u8981\u53d8\u5316\u3002<span style=\"max-width: 100%;font-weight: 700;box-sizing: border-box !important;word-wrap: break-word !important;\">\u5728\u60a3\u8005\u7684\u52a8\u6001\u89c2\u5bdf\u4e2d\uff0c\u7ec4\u7ec7\u75c5\u7406\u68c0\u6d4b\u662f\u5f88\u597d\u7684\u9009\u62e9\uff0c\u4f46\u5373\u65f6\u6027\u8f83\u5dee\u3002\u56e0\u6b64\uff0c\u5728\u8840\u6db2\u4e2d\u8fdb\u884cNGS\u68c0\u6d4b\u662f\u975e\u5e38\u91cd\u8981\u7684\uff0c\u6211\u4eec\u4e5f\u79f0\u4e4b\u4e3a\u6db2\u4f53\u75c5\u7406\u68c0\u6d4b\u3002<\/span>bTMB\u68c0\u6d4b\u975e\u5e38\u91cd\u8981\uff0c\u4e5f\u6781\u5177\u53d1\u5c55\u524d\u666f\u3002\u4e34\u5e8a\u533b\u751f\u5e94\u79ef\u6781\u548c\u6cdb\u751f\u5b50\u7b49\u57fa\u56e0\u68c0\u6d4b\u516c\u53f8\u643a\u624b\u628a\u8fd9\u4e00\u79d1\u5b66\u7814\u7a76\u505a\u597d\uff0c\u8fdb\u4e00\u6b65\u63d0\u9ad8bTMB\u4e0e\u5b9e\u4f53\u7624\u7ec4\u7ec7\u75c5\u7406\u7684\u76f8\u7b26\u7a0b\u5ea6\u3002<\/p>\n<section class=\"\" style=\"margin-top: 20px;margin-bottom: 20px;padding: 5px;max-width: 100%;caret-color: rgb(51, 51, 51);color: rgb(51, 51, 51);letter-spacing: 0.5440000295639038px;text-align: justify;white-space: normal;background-color: rgb(205, 0, 112);font-family: sans-serif;font-size: 16px;box-sizing: border-box !important;word-wrap: break-word !important;\">\n<section class=\"\" style=\"padding: 10px;max-width: 100%;border: 2px solid rgb(255, 255, 255);color: rgb(255, 255, 255);line-height: 24px;box-sizing: border-box !important;word-wrap: break-word !important;\">\n<p style=\"max-width: 100%;word-wrap: break-word;min-height: 1em;line-height: 24px;box-sizing: border-box !important;\"><span style=\"max-width: 100%;font-weight: 700;box-sizing: border-box !important;word-wrap: break-word !important;\">\u5faa\u73af\u80bf\u7624DNA\uff08ctDNA\uff09\u68c0\u6d4b\u56e0\u65b9\u4fbf\u3001\u635f\u4f24\u5c0f\u800c\u5907\u53d7\u9752\u7750\uff0c\u8bf7\u8c08\u8c08\u5b83\u5728\u80bf\u7624\u7684\u6574\u4f53\u8bca\u7597\u8fc7\u7a0b\u4e2d\u7684\u4f5c\u7528\uff1f\u73b0\u6709ctDNA\u68c0\u6d4b\u6280\u672f\u53ca\u5404\u81ea\u7279\u70b9\uff1f<\/span><\/p>\n<\/section>\n<\/section>\n<section class=\"\" style=\"max-width: 100%;caret-color: rgb(51, 51, 51);color: rgb(51, 51, 51);letter-spacing: 0.5440000295639038px;text-align: justify;white-space: normal;font-family: sans-serif;font-size: 16px;box-sizing: border-box !important;word-wrap: break-word !important;\">\n<section class=\"\" style=\"margin-top: 20px;margin-bottom: 10px;padding-top: 20px;padding-bottom: 20px;max-width: 100%;display: -webkit-box;flex-flow: row;border-top-width: 1px;border-top-style: dashed;border-top-color: rgb(204, 0, 111);border-bottom-width: 1px;border-bottom-style: dashed;border-bottom-color: rgb(204, 0, 111);box-sizing: border-box !important;word-wrap: break-word !important;\">\n<section class=\"\" style=\"margin-right: 10px;max-width: 100%;width: 90px;height: 120px;background-color: rgb(214, 214, 221);border-top-left-radius: 2px;border-top-right-radius: 2px;border-bottom-right-radius: 2px;border-bottom-left-radius: 2px;overflow: hidden;box-sizing: border-box !important;word-wrap: break-word !important;\"><img class=\"\"     style=\"display: block;overflow: hidden;box-sizing: border-box !important;word-wrap: break-word !important;width: 90px !important;visibility: visible !important;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/08\/beepress5-1533787925-1.jpeg\" alt=\"\u3010BOA\u5e72\u8d27\u56de\u987e\u3011\u80bf\u7624\u754c\u5927\u5496\u5171\u8bdd\u7cbe\u51c6\u533b\u5b66\u65b0\u98ce\u5411\" title=\"\u3010BOA\u5e72\u8d27\u56de\u987e\u3011\u80bf\u7624\u754c\u5927\u5496\u5171\u8bdd\u7cbe\u51c6\u533b\u5b66\u65b0\u98ce\u5411\"  \/>&nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp;<\/section>\n<section class=\"\" style=\"max-width: 100%;-webkit-box-flex: 1;box-sizing: border-box !important;word-wrap: break-word !important;\">\n<section class=\"\" style=\"margin-right: 5px;max-width: 100%;display: inline-block;font-size: 17px;font-weight: 700;color: rgb(69, 69, 86);box-sizing: border-box !important;word-wrap: break-word !important;\">\u6731\u6167<\/section>\n<section class=\"\" style=\"max-width: 100%;display: inline-block;font-size: 15px;color: rgb(111, 111, 122);box-sizing: border-box !important;word-wrap: break-word !important;\">\u6559\u6388\u3001\u7855\u58eb\u7814\u7a76\u751f\u5bfc\u5e08<\/section>\n<section class=\"\" style=\"margin-top: 10px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\">\n<p style=\"max-width: 100%;word-wrap: break-word;min-height: 1em;font-size: 12px;color: rgb(204, 0, 111);line-height: 18px;box-sizing: border-box !important;\">\u5c71\u4e1c\u7701\u80bf\u7624\u533b\u9662\u653e\u7597\u79d1\u7279\u9700\u75c5\u623f\u526f\u4e3b\u4efb\u533b\u5e08<br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/>\u517c\u4efb\u4e2d\u56fd\u6297\u764c\u534f\u4f1a\u653e\u7597\u4e13\u4e1a\u59d4\u5458\u4f1a\u80ba\u764c\u5b66\u7ec4\u59d4\u5458\u3001\u4e2d\u56fd\u6297\u764c\u534f\u4f1a\u653e\u7597\u4e13\u4e1a\u59d4\u5458\u4f1a\u9752\u5e74\u526f\u4e3b\u4efb\u59d4\u5458\u3001\u5c71\u4e1c\u7701\u6297\u764c\u534f\u4f1a\u653e\u7597\u4e13\u4e1a\u59d4\u5458\u4f1a\u9752\u5e74\u526f\u4e3b\u4efb\u59d4\u5458<br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/>\u7814\u7a76\u65b9\u5411\u4e3a\u80ba\u764c\u7684\u4e34\u5e8a\u548c\u8f6c\u5316\u533b\u5b66\u7814\u7a76\uff0c\u4ee5<br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/>\u7b2c\u4e00\u4f5c\u8005\u548c\u901a\u8baf\u4f5c\u8005\u8bba\u8457\u8fd120\u7bc7\uff0cSCI\u6536\u5f5517\u7bc7\u3002\u4e3b\u6301\u79d1\u6280\u90e8\u91cd\u70b9\u9879\u76ee\u5b50\u8bfe\u9898\u3001\u5c71\u4e1c\u7701\u81ea\u7136\u57fa\u91d1\u9762\u4e0a\u9879\u76ee\u3001 \u5c71\u4e1c\u7701\u79d1\u6280\u653b\u5173\u9879\u76ee\u53caCSCO\u57fa\u91d1\u9879\u76ee<\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<p style=\"margin-top: 20px;margin-bottom: 20px;max-width: 100%;word-wrap: break-word;min-height: 1em;letter-spacing: 0.5440000295639038px;text-align: justify;white-space: normal;font-size: 16px;color: rgb(69, 69, 86);line-height: 26px;font-family: sans-serif;box-sizing: border-box !important;\"><span style=\"max-width: 100%;font-weight: 700;box-sizing: border-box !important;word-wrap: break-word !important;\">\u6731\u6167\u6559\u6388\uff1a<\/span>\u6db2\u6001\u6d3b\u68c0\u5728\u80ba\u764c\u9886\u57df\u4e2d\u7684\u5e94\u7528\u5df2\u7ecf\u975e\u5e38\u5e7f\u6cdb\uff0c\u4e5f\u5f97\u5230\u4e86\u5927\u5bb6\u7684\u8ba4\u53ef\uff0c\u4e0e\u7ec4\u7ec7\u6d3b\u68c0\u8fd9\u4e00\u91d1\u6807\u51c6\u76f8\u6bd4\u4e5f\u6709\u5176\u81ea\u8eab\u7684\u4f18\u52bf\uff0c\u5982\u6613\u83b7\u5f97\u3001\u53ef\u53cd\u590d\u76d1\u6d4b\uff0c\u771f\u6b63\u5b9e\u73b0\u5168\u7a0b\u7684\u52a8\u6001\u76d1\u6d4b\u3002\u8fd9\u79cd\u65e0\u521b\u7684\u68c0\u6d4b\u53ef\u7528\u4e8e\u8010\u836f\u57fa\u56e0\u7684\u7b5b\u67e5\u3001\u75c5\u60c5\u7684\u5168\u7a0b\u76d1\u6d4b\u4ee5\u53ca\u7597\u6548\u7684\u76d1\u63a7\u3002<\/p>\n<p style=\"margin-top: 20px;margin-bottom: 20px;max-width: 100%;word-wrap: break-word;min-height: 1em;letter-spacing: 0.5440000295639038px;text-align: justify;white-space: normal;font-size: 16px;color: rgb(69, 69, 86);line-height: 26px;font-family: sans-serif;box-sizing: border-box !important;\">\u672a\u6765\uff0c\u6db2\u6001\u76d1\u6d4b\u53ef\u7528\u4e8e\u65e9\u671f\u80ba\u764c\u4eba\u7fa4\u7684\u7b5b\u67e5\u3001\u672f\u540e\u8f85\u52a9\u5316\u7597\u7684\u4eba\u7fa4\u9009\u62e9\uff08\u901a\u8fc7\u5916\u5468\u8840\u4e2dctDNA\u7684\u542b\u91cf\u9009\u62e9\u9ad8\u5371\u4eba\u7fa4\uff09\uff0c\u8fd8\u6709\u8010\u836f\u57fa\u56e0\u7684\u7b5b\u67e5\u3002\u53e6\u5916\uff0c<span style=\"max-width: 100%;font-weight: 700;box-sizing: border-box !important;word-wrap: break-word !important;\">\u76ee\u524d\u6cdb\u751f\u5b50\u5f00\u5c55\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u7684\u8fbe\u5c14\u6587\u8ba1\u5212\uff0c\u901a\u8fc7\u6db2\u6001\u6d3b\u68c0\u6280\u672f\u5bf9\u60a3\u8005\u8fdb\u884c\u591a\u6b21\u514d\u8d39\u68c0\u6d4b\uff0c\u80fd\u5b9e\u73b0\u665a\u671f\u60a3\u8005\u9a71\u52a8\u57fa\u56e0\u7684\u76d1\u6d4b\uff0c\u540c\u65f6\u80fd\u76d1\u63a7\u6cbb\u7597\u7597\u6548\uff0c\u5e76\u5728\u51fa\u73b0\u8010\u836f\u540e\u5bf9\u8010\u836f\u57fa\u56e0\u8fdb\u884c\u68c0\u6d4b\uff0c\u8fd8\u80fd\u5bf9\u590d\u53d1\u8f6c\u79fb\u7b49\u6807\u5fd7\u7269\u8fdb\u884c\u68c0\u6d4b\uff0c\u8fd9\u4e9b\u90fd\u975e\u5e38\u5177\u6709\u5b9e\u9645\u610f\u4e49\u3002<\/span><\/p>\n<section class=\"\" style=\"max-width: 100%;caret-color: rgb(51, 51, 51);color: rgb(51, 51, 51);letter-spacing: 0.5440000295639038px;text-align: justify;white-space: normal;font-family: sans-serif;font-size: 16px;box-sizing: border-box !important;word-wrap: break-word !important;\">\n<section class=\"\" style=\"margin-top: 20px;margin-bottom: 10px;padding-top: 20px;padding-bottom: 20px;max-width: 100%;display: -webkit-box;flex-flow: row;border-top-width: 1px;border-top-style: dashed;border-top-color: rgb(204, 0, 111);border-bottom-width: 1px;border-bottom-style: dashed;border-bottom-color: rgb(204, 0, 111);box-sizing: border-box !important;word-wrap: break-word !important;\">\n<section class=\"\" style=\"margin-right: 10px;max-width: 100%;width: 90px;height: 120px;background-color: rgb(214, 214, 221);border-top-left-radius: 2px;border-top-right-radius: 2px;border-bottom-right-radius: 2px;border-bottom-left-radius: 2px;overflow: hidden;box-sizing: border-box !important;word-wrap: break-word !important;\"><img class=\"\"     style=\"display: block;overflow: hidden;box-sizing: border-box !important;word-wrap: break-word !important;width: 90px !important;visibility: visible !important;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/08\/beepress7-1533787925.jpg\" alt=\"\u3010BOA\u5e72\u8d27\u56de\u987e\u3011\u80bf\u7624\u754c\u5927\u5496\u5171\u8bdd\u7cbe\u51c6\u533b\u5b66\u65b0\u98ce\u5411\" title=\"\u3010BOA\u5e72\u8d27\u56de\u987e\u3011\u80bf\u7624\u754c\u5927\u5496\u5171\u8bdd\u7cbe\u51c6\u533b\u5b66\u65b0\u98ce\u5411\"  \/>&nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp;<\/section>\n<section class=\"\" style=\"max-width: 100%;-webkit-box-flex: 1;box-sizing: border-box !important;word-wrap: break-word !important;\">\n<section class=\"\" style=\"margin-right: 5px;max-width: 100%;display: inline-block;font-size: 17px;font-weight: 700;color: rgb(69, 69, 86);box-sizing: border-box !important;word-wrap: break-word !important;\">\u5218\u54f2\u5cf0<\/section>\n<section class=\"\" style=\"max-width: 100%;display: inline-block;font-size: 15px;color: rgb(111, 111, 122);box-sizing: border-box !important;word-wrap: break-word !important;\">\u6559\u6388\u3001\u526f\u4e3b\u4efb\u533b\u5e08\u3001\u7855\u58eb\u751f\u5bfc\u5e08<\/section>\n<section class=\"\" style=\"margin-top: 10px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\">\n<p style=\"max-width: 100%;word-wrap: break-word;min-height: 1em;font-size: 12px;color: rgb(204, 0, 111);line-height: 18px;box-sizing: border-box !important;\">\u89e3\u653e\u519b\u603b\u533b\u9662\u547c\u5438\u80bf\u7624\u53ca\u5185\u955c\u4ecb\u5165\u4e13\u79d1\u526f\u4e3b\u4efb<br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/>\u517c\u4efb\u4e2d\u56fd\u4e34\u5e8a\u80bf\u7624\u5b66\u4f1a\uff08CSCO\uff09\u9752\u5e74\u4e13\u5bb6\u59d4\u5458\u4f1a\u5e38\u52a1\u59d4\u5458\u3001\u5317\u4eac\u4e73\u817a\u75c5\u9632\u6cbb\u5b66\u4f1a\u80bf\u7624\u514d\u75ab\u6cbb\u7597\u4e13\u4e1a\u59d4\u5458\u4f1a\u526f\u4e3b\u4efb\u59d4\u5458\u3001\u5317\u4eac\u533b\u5b66\u5956\u52b1\u57fa\u91d1\u4f1a\u80ba\u764c\u533b\u5b66\u9752\u5e74\u4e13\u5bb6\u59d4\u5458\u4f1a\u526f\u4e3b\u4efb\u59d4\u5458\u3001\u4e2d\u56fd\u7814\u7a76\u578b\u533b\u9662\u5b66\u4f1a\u80bf\u7624\u5b66\u4e13\u4e1a\u59d4\u5458\u4f1a\u5e38\u52a1\u59d4\u5458\u3001\u4e2d\u56fd\u8001\u5e74\u80bf\u7624\u5b66\u4f1a\uff08CGOS\uff09\u59d1\u606f\u4e0e\u5eb7\u590d\u5206\u59d4\u4f1a\u5e38\u52a1\u59d4\u5458\u7b49\u804c\u52a1<br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/>\u83b7\u89e3\u653e\u519b\u603b\u533b\u9662\u5341\u6770\u9752\u5e74<\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<p style=\"margin-top: 20px;margin-bottom: 20px;max-width: 100%;word-wrap: break-word;min-height: 1em;letter-spacing: 0.5440000295639038px;text-align: justify;white-space: normal;font-size: 16px;color: rgb(69, 69, 86);line-height: 26px;font-family: sans-serif;box-sizing: border-box !important;\"><span style=\"max-width: 100%;font-weight: 700;box-sizing: border-box !important;word-wrap: break-word !important;\">\u5218\u54f2\u5cf0\u6559\u6388\uff1a<\/span>\u76ee\u524d\u9488\u5bf9\u6db2\u4f53\u6d3b\u68c0\uff0c\u5c24\u5176\u662f\u8840\u6db2\u4e2dctDNA\u7684\u68c0\u6d4b\u65b9\u6cd5\uff0c\u4e3b\u8981\u6709\uff1a<span style=\"max-width: 100%;font-weight: 700;box-sizing: border-box !important;word-wrap: break-word !important;\">\u4f20\u7edf\u7684ARMS-PCR\u3001\u6700\u65b0\u7684\u9ad8\u7075\u654f\u5ea6ddPCR\u4ee5\u53caNGS\u4e8c\u4ee3\u6d4b\u5e8f\u6cd5<\/span>\u3002\u8fd9\u51e0\u79cd\u65b9\u6cd5\u6709\u5404\u81ea\u7684\u7279\u70b9\uff0c\u5305\u62ec\u68c0\u6d4b\u8303\u56f4\u3001\u68c0\u6d4b\u7075\u654f\u5ea6\u3001\u7ecf\u6d4e\u8d39\u7528\uff0c\u4e34\u5e8a\u4e0a\u9700\u8981\u6839\u636e\u60a3\u8005\u7684\u60c5\u51b5\u8fdb\u884c\u9009\u62e9\u3002\u4e00\u822c\u6765\u8bf4\uff0c\u5bf9\u4e8e\u5df2\u77e5\u7684\u836f\u7269\u654f\u611f\u57fa\u56e0\u6216\u8010\u836f\u57fa\u56e0\u8fdb\u884c\u5355\u57fa\u56e0\u7684\u4f4d\u70b9\u68c0\u6d4b\uff0c\u63a8\u8350\u4f7f\u7528ddPCR\u6cd5\uff0c\u5176\u7075\u654f\u5ea6\u66f4\u9ad8\u3001\u65f6\u95f4\u66f4\u77ed\u3001\u8d39\u7528\u66f4\u4f4e\u3002\u800c\u9488\u5bf9\u672a\u77e5\u57fa\u56e0\u8fdb\u884c\u7b5b\u9009\u5219\u66f4\u63a8\u8350NGS\u6cd5\uff0c\u5176\u4f18\u70b9\u662f\u80fd\u63d0\u4f9b\u66f4\u5927\u7684\u4fe1\u606f\u91cf\uff0c\u7ed9\u4e34\u5e8a\u63d0\u4f9b\u66f4\u591a\u9009\u62e9\uff0c\u4f46\u8d39\u7528\u76f8\u5bf9\u8f83\u9ad8\uff0c\u65f6\u95f4\u8f83\u957f\uff0c\u9700\u8981\u533b\u751f\u4e0e\u60a3\u8005\u8010\u5fc3\u7b49\u5f85\u3002\u56e0\u6b64\uff0c<span style=\"max-width: 100%;font-weight: 700;box-sizing: border-box !important;word-wrap: break-word !important;\">\u5e94\u8be5\u6839\u636e\u4e0d\u540c\u7684\u60a3\u8005\u60c5\u51b5\u4e0e\u4e0d\u540c\u7684\u75be\u75c5\u9700\u6c42\u9009\u7528\u76f8\u5e94\u7684ctDNA\u68c0\u6d4b\u65b9\u6cd5\u3002<\/span><\/p>\n<section class=\"\" style=\"margin-top: 20px;margin-bottom: 20px;padding: 5px;max-width: 100%;caret-color: rgb(51, 51, 51);color: rgb(51, 51, 51);letter-spacing: 0.5440000295639038px;text-align: justify;white-space: normal;background-color: rgb(205, 0, 112);font-family: sans-serif;font-size: 16px;box-sizing: border-box !important;word-wrap: break-word !important;\">\n<section class=\"\" style=\"padding: 10px;max-width: 100%;border: 2px solid rgb(255, 255, 255);color: rgb(255, 255, 255);line-height: 24px;box-sizing: border-box !important;word-wrap: break-word !important;\">\n<p style=\"max-width: 100%;word-wrap: break-word;min-height: 1em;line-height: 24px;box-sizing: border-box !important;\"><span style=\"max-width: 100%;font-weight: 700;box-sizing: border-box !important;word-wrap: break-word !important;\">\u7cbe\u51c6\u533b\u5b66\u65f6\u4ee3\uff0c\u57fa\u56e0\u68c0\u6d4b\u5728\u6d88\u5316\u9053\u80bf\u7624\u548c\u80ba\u764c\u4e2d\u7684\u5e94\u7528<\/span><\/p>\n<\/section>\n<\/section>\n<section class=\"\" style=\"margin-top: 20px;margin-bottom: 20px;max-width: 100%;letter-spacing: 0.5440000295639038px;text-align: justify;white-space: normal;font-size: 16px;line-height: 24px;color: rgb(205, 0, 112);font-weight: 700;display: -webkit-box;flex-flow: row;font-family: sans-serif;box-sizing: border-box !important;word-wrap: break-word !important;\">\n<section class=\"\" style=\"margin-right: 4px;max-width: 100%;height: 24px;box-sizing: border-box !important;word-wrap: break-word !important;\">\n<section class=\"\" style=\"margin-top: 4px;max-width: 100%;float: left;border-left-width: 8px;border-left-style: solid;border-left-color: rgb(205, 0, 112);border-top-width: 8px;border-top-style: solid;border-top-color: transparent;border-bottom-width: 8px;border-bottom-style: solid;border-bottom-color: transparent;opacity: 0.6;box-sizing: border-box !important;word-wrap: break-word !important;\"><\/section>\n<section class=\"\" style=\"margin-top: 4px;max-width: 100%;float: left;border-left-width: 8px;border-left-style: solid;border-left-color: rgb(205, 0, 112);border-top-width: 8px;border-top-style: solid;border-top-color: transparent;border-bottom-width: 8px;border-bottom-style: solid;border-bottom-color: transparent;box-sizing: border-box !important;word-wrap: break-word !important;\"><\/section>\n<\/section>\n<section class=\"\" style=\"max-width: 100%;-webkit-box-flex: 1;box-sizing: border-box !important;word-wrap: break-word !important;\">\n<p style=\"max-width: 100%;word-wrap: break-word;min-height: 1em;line-height: 24px;box-sizing: border-box !important;\">\u5728\u6d88\u5316\u9053\u80bf\u7624\u4e2d\u7684\u5e94\u7528<\/p>\n<\/section>\n<\/section>\n<section class=\"\" style=\"max-width: 100%;caret-color: rgb(51, 51, 51);color: rgb(51, 51, 51);letter-spacing: 0.5440000295639038px;text-align: justify;white-space: normal;font-family: sans-serif;font-size: 16px;box-sizing: border-box !important;word-wrap: break-word !important;\">\n<section class=\"\" style=\"margin-top: 20px;margin-bottom: 10px;padding-top: 20px;padding-bottom: 20px;max-width: 100%;display: -webkit-box;flex-flow: row;border-top-width: 1px;border-top-style: dashed;border-top-color: rgb(204, 0, 111);border-bottom-width: 1px;border-bottom-style: dashed;border-bottom-color: rgb(204, 0, 111);box-sizing: border-box !important;word-wrap: break-word !important;\">\n<section class=\"\" style=\"margin-right: 10px;max-width: 100%;width: 90px;height: 120px;background-color: rgb(214, 214, 221);border-top-left-radius: 2px;border-top-right-radius: 2px;border-bottom-right-radius: 2px;border-bottom-left-radius: 2px;overflow: hidden;box-sizing: border-box !important;word-wrap: break-word !important;\"><img class=\"\"     style=\"display: block;overflow: hidden;box-sizing: border-box !important;word-wrap: break-word !important;width: 90px !important;visibility: visible !important;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/08\/beepress7-1533787926.jpeg\" alt=\"\u3010BOA\u5e72\u8d27\u56de\u987e\u3011\u80bf\u7624\u754c\u5927\u5496\u5171\u8bdd\u7cbe\u51c6\u533b\u5b66\u65b0\u98ce\u5411\" title=\"\u3010BOA\u5e72\u8d27\u56de\u987e\u3011\u80bf\u7624\u754c\u5927\u5496\u5171\u8bdd\u7cbe\u51c6\u533b\u5b66\u65b0\u98ce\u5411\"  \/>&nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp;<\/section>\n<section class=\"\" style=\"max-width: 100%;-webkit-box-flex: 1;box-sizing: border-box !important;word-wrap: break-word !important;\">\n<section class=\"\" style=\"margin-right: 5px;max-width: 100%;display: inline-block;font-size: 17px;font-weight: 700;color: rgb(69, 69, 86);box-sizing: border-box !important;word-wrap: break-word !important;\">\u5f6d\u667a<\/section>\n<section class=\"\" style=\"max-width: 100%;display: inline-block;font-size: 15px;color: rgb(111, 111, 122);box-sizing: border-box !important;word-wrap: break-word !important;\">\u526f\u6559\u6388\u3001\u533b\u5b66\u535a\u58eb<\/section>\n<section class=\"\" style=\"margin-top: 10px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\">\n<p style=\"max-width: 100%;word-wrap: break-word;min-height: 1em;font-size: 12px;color: rgb(204, 0, 111);line-height: 18px;box-sizing: border-box !important;\">\u5317\u4eac\u5927\u5b66\u533b\u5b66\u90e8\u548c\u5317\u4eac\u5927\u5b66\u4f18\u79c0\u535a\u58eb\u540e<br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/>\u73b0\u5c31\u804c\u4e8e\u5317\u4eac\u5927\u5b66\u80bf\u7624\u533b\u9662\u6d88\u5316\u80bf\u7624\u5185\u79d1<br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/>\u517c\u4efb\u4e2d\u56fd\u6297\u764c\u534f\u4f1a\u6574\u5408\u80bf\u7624\u5b66\u5206\u4f1a\u9752\u59d4\u59d4\u5458\u3001\u4e2d\u56fd\u6297\u764c\u534f\u4f1a\u80c3\u764c\u4e13\u4e1a\u59d4\u5458\u4f1a\u5185\u79d1\u5b66\u7ec4\u59d4\u5458\u3001\u300a\u80bf\u7624\u7efc\u5408\u6cbb\u7597\u7535\u5b50\u6742\u5fd7\u300b\u7f16\u59d4<br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/>\u4e3b\u6301\u5305\u62ec\u56fd\u5bb6\u81ea\u7136\u79d1\u5b66\u57fa\u91d1\u3001\u4e2d\u56fd\u535a\u58eb\u540e\u57fa\u91d1\u3001\u5317\u4eac\u5e02\u81ea\u7136\u79d1\u5b66\u57fa\u91d1\u7b49\u591a\u9879\u79d1\u7814\u57fa\u91d1\u9879\u76ee\uff0c\u4ee5\u7b2c\u4e00\u4f5c\u8005\u53d1\u8868SCI\u6536\u5f55\u8bba\u6587\u8fd110\u7bc7\uff0c\u83b7\u5f97\u56fd\u5bb6\u53d1\u660e\u4e13\u52291\u9879\uff0c\u53c2\u8bd1\u533b\u5b66\u4e13\u84572\u672c\u30022016\u5e74\u5ea6\u534e\u590f\u533b\u5b66\u79d1\u6280\u5956\u4e00\u7b49\u5956<\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<p style=\"margin-top: 20px;margin-bottom: 20px;max-width: 100%;word-wrap: break-word;min-height: 1em;letter-spacing: 0.5440000295639038px;text-align: justify;white-space: normal;font-size: 16px;color: rgb(69, 69, 86);line-height: 26px;font-family: sans-serif;box-sizing: border-box !important;\"><span style=\"max-width: 100%;font-weight: 700;box-sizing: border-box !important;word-wrap: break-word !important;\">\u5f6d\u667a\u6559\u6388\uff1a<\/span>\u6d88\u5316\u9053\u80bf\u7624\u6db5\u76d6\u4e86\u591a\u4e2a\u7624\u79cd\uff0c\u6bcf\u4e2a\u7624\u79cd\u90fd\u4e0d\u5c3d\u76f8\u540c\u3002\u57fa\u56e0\u68c0\u6d4b\u5728\u6d88\u5316\u9053\u80bf\u7624\u7684\u5e94\u7528\uff0c\u6700\u65e9\u5e94\u8ffd\u6eaf\u5230\u80c3\u80a0\u95f4\u8d28\u7624\uff0c<span class=\"\" style=\"max-width: 100%;font-style: italic;box-sizing: border-box !important;word-wrap: break-word !important;\">c-kit<\/span>\u7a81\u53d8\u3001<span class=\"\" style=\"max-width: 100%;font-style: italic;box-sizing: border-box !important;word-wrap: break-word !important;\">PDGFR<\/span>\u7a81\u53d8\u90fd\u4e0e\u6cbb\u7597\u7597\u6548\u3001\u8bca\u65ad\u5bc6\u5207\u76f8\u5173\u3002\u540e\u7eed\u62d3\u5c55\u5230\u7ed3\u76f4\u80a0\u764c\u7684<span class=\"\" style=\"max-width: 100%;font-style: italic;box-sizing: border-box !important;word-wrap: break-word !important;\">KRAS<\/span>\u3001<span class=\"\" style=\"max-width: 100%;font-style: italic;box-sizing: border-box !important;word-wrap: break-word !important;\">NRAS&nbsp;<\/span>\u548c&nbsp;<span class=\"\" style=\"max-width: 100%;font-style: italic;box-sizing: border-box !important;word-wrap: break-word !important;\">BRAF&nbsp;<\/span>\u7b49\u7a81\u53d8\u68c0\u6d4b\uff0c\u4ee5\u53ca\u80c3\u764c&nbsp;<span class=\"\" style=\"max-width: 100%;font-style: italic;box-sizing: border-box !important;word-wrap: break-word !important;\">HER2&nbsp;<\/span>\u7684\u68c0\u6d4b\u7b49\u3002<\/p>\n<p style=\"margin-top: 20px;margin-bottom: 20px;max-width: 100%;word-wrap: break-word;min-height: 1em;letter-spacing: 0.5440000295639038px;text-align: justify;white-space: normal;font-size: 16px;color: rgb(69, 69, 86);line-height: 26px;font-family: sans-serif;box-sizing: border-box !important;\">\u968f\u7740\u57fa\u56e0\u68c0\u6d4b\u6280\u672f\u7684\u4e0d\u65ad\u8fdb\u6b65\u4ee5\u53ca\u80bf\u7624\u751f\u7269\u5b66\u884c\u4e3a\u4e0e\u5206\u5b50\u673a\u5236\u7684\u4e0d\u65ad\u53d1\u5c55\uff0c<span style=\"max-width: 100%;font-weight: 700;box-sizing: border-box !important;word-wrap: break-word !important;\">\u4e34\u5e8a\u4e0a\u9700\u8981\u8fdb\u884c\u66f4\u591a\u7684\u57fa\u56e0\u68c0\u6d4b<\/span>\uff0c\u5305\u62ec\u5bf9\u4e8e\u8bca\u65ad\u4e0e\u6cbb\u7597\u7684\u8865\u5145\uff0c\u5982PD-1\u5355\u6297\u7684\u7597\u6548\u5224\u65ad\uff1a\u54ea\u4e9b\u60a3\u8005\u662f\u83b7\u76ca\u4eba\u7fa4\uff0c\u54ea\u4e9b\u60a3\u8005\u53ef\u80fd\u53d1\u751f\u8d85\u8fdb\u5c55\uff0c\u54ea\u4e9b\u60a3\u8005\u662f\u65e0\u6548\u7684\uff0c\u54ea\u4e9b\u60a3\u8005\u4f1a\u53d1\u751f\u7ee7\u53d1\u8010\u836f\u7b49\uff0c\u5206\u5b50\u68c0\u6d4b\u90fd\u80fd\u63d0\u4f9b\u63d0\u793a\u6027\u4fe1\u606f\u3002\u5b9e\u9645\u4e0a\uff0c\u76ee\u524d\u7684\u5e38\u89c4\u8bca\u7597\u4ecd\u672a\u8ddf\u4e0a\uff0c\u5f88\u591a\u4fe1\u606f\u662f\u7814\u7a76\u6027\u8d28\u7684\uff0c\u5e76\u672a\u5728\u6307\u5357\u89c4\u8303\u4e2d\u63d0\u5230\u3002<span style=\"max-width: 100%;font-weight: 700;box-sizing: border-box !important;word-wrap: break-word !important;\">\u53bb\u5e74FDA\u6279\u51c6PD-1\u6291\u5236\u5242\u7528\u4e8eMSI-H\u6216DNA\u9519\u914d\u4fee\u590d\u7f3a\u9677\uff08dMMR\uff09\u7684\u60a3\u8005\uff0c\u8fd9\u662f\u9996\u6b21\u901a\u8fc7\u5206\u5b50\u68c0\u6d4b\u3001\u4e0d\u9650\u7624\u79cd\u5730\u6279\u51c6\u836f\u7269\u4e0a\u5e02\uff0c\u662f\u5206\u5b50\u68c0\u6d4b\u9886\u57df\u91cd\u5927\u7684\u91cc\u7a0b\u7891\u3002<\/span><\/p>\n<p style=\"margin-top: 20px;margin-bottom: 20px;max-width: 100%;word-wrap: break-word;min-height: 1em;letter-spacing: 0.5440000295639038px;text-align: justify;white-space: normal;font-size: 16px;color: rgb(69, 69, 86);line-height: 26px;font-family: sans-serif;box-sizing: border-box !important;\">\u4eca\u5e74ASCO\u8ba8\u8bba\u4e86\u5f88\u591a\u901a\u8fc7<span style=\"max-width: 100%;font-weight: 700;box-sizing: border-box !important;word-wrap: break-word !important;\">\u6db2\u4f53\u6d3b\u68c0\u68c0\u6d4bctDNA\u3001\u5faa\u73af\u6e38\u79bbDNA\uff08cfDNA\uff09\u3001\u5faa\u73af\u80bf\u7624\u7ec6\u80de\uff08CTC\uff09\u548cbTMB<\/span>\u7684\u8bae\u9898\u3002\u5bf9\u4e8e\u80bf\u7624\u7684\u836f\u7269\u6cbb\u7597\uff0c\u7279\u522b\u662f\u5728\u8010\u836f\u95ee\u9898\u3001\u540e\u7eed\u836f\u7269\u7684\u9009\u62e9\u95ee\u9898\uff0c\u4ee5\u53cabTMB\u5982\u4f55\u6307\u5bfcPD-1\u5355\u6297\u6cbb\u7597\u65b9\u9762\u90fd\u6709\u4e00\u4e9b\u65b0\u8fdb\u5c55\u3002\u968f\u7740\u6280\u672f\u7684\u4e0d\u65ad\u8fdb\u6b65\uff0c\u66f4\u591a\u7684\u5206\u5b50\u68c0\u6d4b\u4ea7\u54c1\u4f1a\u8fd0\u7528\u5230\u80bf\u7624\u7684\u8bca\u65ad\u548c\u6cbb\u7597\uff0c\u7279\u522b\u662f\u5728\u52a8\u6001\u76d1\u6d4b\u8fc7\u7a0b\u4e2d\u4f1a\u51fa\u73b0\u66f4\u591a\u7684\u65b0\u4ea7\u54c1\u3001\u65b0\u65b9\u6cd5\u3002<\/p>\n<section class=\"\" style=\"margin-top: 20px;margin-bottom: 20px;max-width: 100%;letter-spacing: 0.5440000295639038px;text-align: justify;white-space: normal;font-size: 16px;line-height: 24px;color: rgb(205, 0, 112);font-weight: 700;display: -webkit-box;flex-flow: row;font-family: sans-serif;box-sizing: border-box !important;word-wrap: break-word !important;\">\n<section class=\"\" style=\"margin-right: 4px;max-width: 100%;height: 24px;box-sizing: border-box !important;word-wrap: break-word !important;\">\n<section class=\"\" style=\"margin-top: 4px;max-width: 100%;float: left;border-left-width: 8px;border-left-style: solid;border-left-color: rgb(205, 0, 112);border-top-width: 8px;border-top-style: solid;border-top-color: transparent;border-bottom-width: 8px;border-bottom-style: solid;border-bottom-color: transparent;opacity: 0.6;box-sizing: border-box !important;word-wrap: break-word !important;\"><\/section>\n<section class=\"\" style=\"margin-top: 4px;max-width: 100%;float: left;border-left-width: 8px;border-left-style: solid;border-left-color: rgb(205, 0, 112);border-top-width: 8px;border-top-style: solid;border-top-color: transparent;border-bottom-width: 8px;border-bottom-style: solid;border-bottom-color: transparent;box-sizing: border-box !important;word-wrap: break-word !important;\"><\/section>\n<\/section>\n<section class=\"\" style=\"max-width: 100%;-webkit-box-flex: 1;box-sizing: border-box !important;word-wrap: break-word !important;\">\n<p style=\"max-width: 100%;word-wrap: break-word;min-height: 1em;line-height: 24px;box-sizing: border-box !important;\">\u5728\u80ba\u764c\u4e2d\u7684\u5e94\u7528<\/p>\n<\/section>\n<\/section>\n<p style=\"margin-top: 20px;margin-bottom: 20px;max-width: 100%;word-wrap: break-word;min-height: 1em;letter-spacing: 0.5440000295639038px;text-align: justify;white-space: normal;font-size: 16px;color: rgb(69, 69, 86);line-height: 26px;font-family: sans-serif;box-sizing: border-box !important;\"><span style=\"max-width: 100%;font-weight: 700;box-sizing: border-box !important;word-wrap: break-word !important;\">\u5218\u54f2\u5cf0\u6559\u6388\uff1a<\/span>\u76ee\u524d\uff0c\u9776\u5411\u6cbb\u7597\u7684\u8010\u836f\u673a\u5236\u7814\u7a76\u4e3b\u8981\u96c6\u4e2d\u5728\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u9886\u57df\uff0c\u5176\u4e2dEGFR\u901a\u8def\u8010\u836f\u673a\u5236\u7684\u7814\u7a76\u76f8\u5bf9\u900f\u5f7b\u3002\u4eca\u5e74ASCO\u4e0a\uff0c<span style=\"max-width: 100%;font-weight: 700;box-sizing: border-box !important;word-wrap: break-word !important;\">\u66f4\u591a\u7684\u7814\u7a76\u70ed\u70b9\u96c6\u4e2d\u5728\u4e09\u4ee3\u7684EGFR TKI\u8010\u836f\u540e\u7684\u8010\u836f\u673a\u5236\u7814\u7a76\uff0c\u4ee5\u53caALK\u878d\u5408\u57fa\u56e0\u5728\u4e00\/\u4e8c\u4ee3ALK TKI\u8010\u836f\u540e\u51fa\u73b0\u7684\u4e0d\u540c\u8010\u836f\u6a21\u5f0f\u3002<\/span><\/p>\n<p style=\"margin-top: 20px;margin-bottom: 20px;max-width: 100%;word-wrap: break-word;min-height: 1em;letter-spacing: 0.5440000295639038px;text-align: justify;white-space: normal;font-size: 16px;color: rgb(69, 69, 86);line-height: 26px;font-family: sans-serif;box-sizing: border-box !important;\">\u9488\u5bf9EGFR\u901a\u8def\uff0c\u4e00\/\u4e8c\u4ee3TKI\u8010\u836f\u6a21\u5f0f\u4e3b\u8981\u96c6\u4e2d\u5728\u4ee5\u4e0b\u4e09\u79cd\u60c5\u51b5\uff1a<span style=\"max-width: 100%;font-weight: 700;box-sizing: border-box !important;word-wrap: break-word !important;\">\u6d3b\u5316\u57fa\u56e0\u7684\u7a81\u53d8\uff1b\u65c1\u8def\u7684\u6269\u589e\u548c\u6fc0\u6d3b\uff1b\u7ec6\u80de\u8868\u578b\u7684\u8f6c\u5316<\/span>\u3002\u4e09\u4ee3TKI\u5965\u5e0c\u66ff\u5c3c\u7684\u8010\u836f\u6a21\u5f0f\u4e0e\u4e00\/\u4e8c\u4ee3TKI\u57fa\u672c\u4e00\u81f4\uff0c\u53ea\u662f\u7a81\u53d8\u4f4d\u70b9\u53ca\u5176\u6bd4\u4f8b\u4e0d\u540c\u3002\u4e00\/\u4e8c\u4ee3TKI\u8010\u836f\u540e\uff0c\u6700\u5e38\u89c1\u7684\u7a81\u53d8\u4f4d\u70b9\u662f20\u5916\u663e\u5b50T790M\u7a81\u53d8\uff0c\u5360\u6bd4\u7ea6\u4e3a50%-60%\uff1b\u53e6\u5916\uff0c15%-20%\u7684\u60a3\u8005\u4f1a\u51fa\u73b0C-MET\u6269\u589e\uff1b\u8fd8\u67095%\u7684\u60a3\u8005\u4f1a\u51fa\u73b0\u5c0f\u7ec6\u80de\u80ba\u764c\u7684\u8f6c\u5316\u3002\u800c\u4e09\u4ee3TKI\u5965\u5e0c\u66ff\u5c3c\u8010\u836f\u540e\uff0c\u76ee\u524d\u5360\u6bd4\u6700\u5927\u7684\u8010\u836f\u4f4d\u70b9\u662fC797S\u7684\u77ac\u65f6\u7a81\u53d8\uff0c\u5176\u4ed6\u7684\u65c1\u8def\u6fc0\u6d3b\u4e0e\u5c0f\u7ec6\u80de\u80ba\u764c\u7684\u8f6c\u5316\u4e5f\u5206\u522b\u5360\u6709\u4e00\u5b9a\u7684\u6bd4\u4f8b\uff0c\u4f8b\u5982C-MET\u6269\u589e\u7ea615%-20%\uff0c\u540c\u65f6\u8fd8\u6709KRAS\u7a81\u53d8\u3001BRAF\u7a81\u53d8\u3001mTOR\u901a\u8def\u6fc0\u6d3b\uff0c\u4ee5\u53ca\u5c0f\u7ec6\u80de\u80ba\u764c\u8868\u578b\u7684\u8f6c\u5316\u3002\u56e0\u6b64\uff0cNGS\u68c0\u6d4b\u5728\u6574\u4e2a\u6cbb\u7597\u8fc7\u7a0b\u4e0e\u8010\u836f\u9636\u6bb5\u90fd\u5177\u6709\u91cd\u8981\u7684\u4ef7\u503c\u3002<\/p>\n<section class=\"\"   style=\"max-width: 100%;box-sizing: border-box;caret-color: rgb(51, 51, 51);color: rgb(51, 51, 51);\">\n<section  class=\"\" style=\"max-width: 100%;box-sizing: border-box;border: 0px none;word-wrap: break-word !important;\">\n<section style=\"padding: 10px;max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<section  style=\"margin: 20px auto;max-width: 100%;width: 650px;box-sizing: border-box !important;word-wrap: break-word !important;\">\n<section  style=\"margin: -20px auto;max-width: 100%;width: 617.5px;box-sizing: border-box !important;word-wrap: break-word !important;\">\n<p style=\"max-width: 100%;min-height: 1em;text-align: center;box-sizing: border-box !important;word-wrap: break-word !important;\"><img class=\"__bg_gif\"    title=\"\u3010BOA\u5e72\u8d27\u56de\u987e\u3011\u80bf\u7624\u754c\u5927\u5496\u5171\u8bdd\u7cbe\u51c6\u533b\u5b66\u65b0\u98ce\u5411\" width=\"auto\"  style=\"display: inline;box-sizing: border-box !important;word-wrap: break-word !important;visibility: visible !important;width: auto !important;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/08\/beepress9-1533787926.gif\" alt=\"\u3010BOA\u5e72\u8d27\u56de\u987e\u3011\u80bf\u7624\u754c\u5927\u5496\u5171\u8bdd\u7cbe\u51c6\u533b\u5b66\u65b0\u98ce\u5411\"  \/><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<p style=\"max-width: 100%;min-height: 1em;caret-color: rgb(51, 51, 51);color: rgb(51, 51, 51);\"><br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/p>\n<section class=\"\"   style=\"max-width: 100%;box-sizing: border-box;caret-color: rgb(51, 51, 51);color: rgb(51, 51, 51);\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;border: 0px none;word-wrap: break-word !important;\">\n<section  style=\"max-width: 100%;width: 670px;box-sizing: border-box !important;word-wrap: break-word !important;\">\n<section class=\"\" style=\"margin-top: -25px;margin-right: auto;margin-left: auto;padding: 15px;max-width: 100%;box-sizing: border-box;line-height: 28px;background-color: rgb(223, 253, 254);word-wrap: break-word !important;\">\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\">\u57fa\u56e0\u4ff1\u4e50\u90e8\u65b0\u589e\u4e24\u4efd\u91cd\u91cf\u7ea7\uff1a<\/strong><\/p>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;word-wrap: break-word !important;\"><img class=\"\"      width=\"auto\"  style=\"box-sizing: border-box !important;word-wrap: break-word !important;visibility: visible !important;width: auto !important;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/08\/beepress7-1533787926.jpg\" alt=\"\u3010BOA\u5e72\u8d27\u56de\u987e\u3011\u80bf\u7624\u754c\u5927\u5496\u5171\u8bdd\u7cbe\u51c6\u533b\u5b66\u65b0\u98ce\u5411\" title=\"\u3010BOA\u5e72\u8d27\u56de\u987e\u3011\u80bf\u7624\u754c\u5927\u5496\u5171\u8bdd\u7cbe\u51c6\u533b\u5b66\u65b0\u98ce\u5411\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;word-wrap: break-word !important;\">\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;word-wrap: break-word !important;\"><a href=\"https:\/\/mp.weixin.qq.com\/s?__biz=MzIwMTQ3MDc4Mw==&amp;mid=2247493206&amp;idx=2&amp;sn=5a9a8d6d186e36b2a032bc37206517a6&amp;scene=21#wechat_redirect\" target=\"_blank\" style=\"color: rgb(87, 107, 149);text-decoration: underline;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;color: rgb(255, 41, 65);box-sizing: border-box !important;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\">\u57fa\u56e0\u4ff1\u4e50\u90e8\u2014\u57fa\u56e0\u79d1\u6280\u884c\u4e1a\u3001\u4e13\u4e1a\u53ca\u6295\u8d44\u4eba\u58eb\u7684\u79c1\u5bc6\u4e16\u754c\uff0c\u4e00\u4e2a\u6709\u4ef7\u503c\u7684\u57fa\u56e0\u79d1\u6280\u8d44\u8baf\u3001\u4ea4\u6d41\u4e0e\u4e92\u52a8\u5e73\u53f0\u3002<\/strong><\/span><span style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"><\/strong><strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"><\/strong><\/span><br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/a><\/p>\n<p><a href=\"https:\/\/mp.weixin.qq.com\/s?__biz=MzIwMTQ3MDc4Mw==&amp;mid=2247493206&amp;idx=2&amp;sn=5a9a8d6d186e36b2a032bc37206517a6&amp;scene=21#wechat_redirect\" target=\"_blank\" style=\"color: rgb(87, 107, 149);text-decoration: underline;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;color: rgb(0, 82, 255);font-size: 15px;box-sizing: border-box !important;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\">\u70b9\u51fb\u52a0\u5165\u57fa\u56e0\u4ff1\u4e50\u90e8\uff0c\u6210\u5c31\u884c\u4e1a\u7cbe\u82f1\uff0c\u5c0a\u4eab\u57fa\u56e0\u76db\u5bb4\uff01<\/strong><\/span><\/a><\/section>\n<\/section>\n<\/section>\n<\/section>\n<p style=\"max-width: 100%;min-height: 1em;caret-color: rgb(51, 51, 51);color: rgb(51, 51, 51);\"><img class=\"\"      width=\"auto\"  style=\"box-sizing: border-box !important;word-wrap: break-word !important;visibility: visible !important;width: auto !important;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/08\/beepress6-1533787926.jpeg\" alt=\"\u3010BOA\u5e72\u8d27\u56de\u987e\u3011\u80bf\u7624\u754c\u5927\u5496\u5171\u8bdd\u7cbe\u51c6\u533b\u5b66\u65b0\u98ce\u5411\" title=\"\u3010BOA\u5e72\u8d27\u56de\u987e\u3011\u80bf\u7624\u754c\u5927\u5496\u5171\u8bdd\u7cbe\u51c6\u533b\u5b66\u65b0\u98ce\u5411\"  \/><\/p>\n<blockquote class='keep-source'>\n<p>\u59cb\u53d1\u4e8e\u5fae\u4fe1\u516c\u4f17\u53f7\uff1a                         \u57fa\u56e0\u8c37                      <\/p>\n<\/blockquote>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>\u6765\u6e90\uff1a\u80bf\u7624\u8d44\u8baf \u57282018\u201cBest of ASCO\uff08BOA\uff09\u201d\u4e2d\u5404\u8def\u80bf\u7624\u5927\u5496\u9f50\u805a\u4e00\u5802\uff0c\u4e00\u540c\u56de\u987e\u4e0e\u63a2\u8ba8\u4eca\u5e74AS [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":30860,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[2],"tags":[],"_links":{"self":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/30859"}],"collection":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/comments?post=30859"}],"version-history":[{"count":1,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/30859\/revisions"}],"predecessor-version":[{"id":30874,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/30859\/revisions\/30874"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/media\/30860"}],"wp:attachment":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/media?parent=30859"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/categories?post=30859"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/tags?post=30859"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}