{"id":31549,"date":"2018-08-01T01:00:00","date_gmt":"2018-08-09T04:17:04","guid":{"rendered":"http:\/\/www.05921.net\/index.php\/2018\/08\/09\/cell%ef%bc%9a%e4%b8%8b%e5%8d%885%e7%82%b9%ef%bc%8c%e7%94%9f%e7%89%a9%e9%92%9f%e4%bf%83%e8%bf%9b%e8%84%82%e8%82%aa%e7%87%83%e7%83%a7%e7%9a%84%e9%bb%84%e9%87%91%e6%9c%9f\/"},"modified":"2018-08-09T12:17:06","modified_gmt":"2018-08-09T04:17:06","slug":"cell%ef%bc%9a%e4%b8%8b%e5%8d%885%e7%82%b9%ef%bc%8c%e7%94%9f%e7%89%a9%e9%92%9f%e4%bf%83%e8%bf%9b%e8%84%82%e8%82%aa%e7%87%83%e7%83%a7%e7%9a%84%e9%bb%84%e9%87%91%e6%9c%9f","status":"publish","type":"post","link":"https:\/\/www.05921.net\/index.php\/31549\/","title":{"rendered":"Cell\uff1a\u4e0b\u53485\u70b9\uff0c\u751f\u7269\u949f\u4fc3\u8fdb\u8102\u80aa\u71c3\u70e7\u7684\u201c\u9ec4\u91d1\u671f\u201d"},"content":{"rendered":"<div class=\"bpp-post-content\">\n<section class=\"xmteditor\" style=\"display:none;\"  ><\/section>\n<section  class=\"\" style=\"max-width: 100%;text-align: justify;white-space: normal;background-color: rgb(255, 255, 255);font-size: 16px;letter-spacing: 0.476px;color: rgb(62, 62, 62);font-family: \u5fae\u8f6f\u96c5\u9ed1;box-sizing: border-box !important;word-wrap: break-word !important;\">\n<section class=\"\" style=\"max-width: 100%;border-width: 0px;border-style: none;border-color: initial;box-sizing: border-box !important;word-wrap: break-word !important;\">\n<section class=\"\" style=\"max-width: 100%;border-width: 0px;border-style: none;border-color: initial;box-sizing: border-box !important;word-wrap: break-word !important;\">\n<section class=\"\" style=\"padding: 0.8em;max-width: 100%;border-width: 1px 0.4em;border-style: solid;border-color: rgb(172, 29, 16);border-radius: 0.3em;box-sizing: border-box !important;word-wrap: break-word !important;\">\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;word-wrap: break-word !important;\">\u5f88\u591a\u4eba\u4e4b\u6240\u4ee5\u80a5\u80d6\u4e0e\u201c\u8425\u517b\u8fc7\u5269\u201d\u6709\u5173\u8054\uff0c\u8fd9\u4e00\u996e\u98df\u56e0\u7d20\u4f1a\u5f71\u54cd\u751f\u7269\u949f\uff0c\u4f46\u662f\u80cc\u540e\u7684\u673a\u5236\u5374\u4e0d\u6e05\u6670\u3002\u73b0\u5728\uff0c\u6700\u65b0\u4e00\u9879\u7814\u7a76\u63ed\u793a\uff0c\u9ad8\u8102\u80aa\u996e\u98df\u4f1a\u4fc3\u4f7f\u5c0f\u9f20\u4ea7\u751f\u65b0\u7684\u809d\u810f\u201c\u751f\u7269\u949f\u201d\uff0c\u4ece\u800c\u5f71\u54cd\u8102\u80aa\u7684\u56e4\u79ef\u548c\u6d88\u8017\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"><\/p>\n<p style=\"line-height: 1.75em;text-align: center;\"><img class=\"\"     style=\"margin-top: 6px;margin-bottom: 6px;border-width: 0px;border-style: none;border-color: initial;vertical-align: middle;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/08\/beepress1-1533788225.jpeg\" alt=\"Cell\uff1a\u4e0b\u53485\u70b9\uff0c\u751f\u7269\u949f\u4fc3\u8fdb\u8102\u80aa\u71c3\u70e7\u7684\u201c\u9ec4\u91d1\u671f\u201d\" title=\"Cell\uff1a\u4e0b\u53485\u70b9\uff0c\u751f\u7269\u949f\u4fc3\u8fdb\u8102\u80aa\u71c3\u70e7\u7684\u201c\u9ec4\u91d1\u671f\u201d\"><\/p>\n<p style=\"line-height: 1.75em;text-align: justify;\"><span style=\"color: rgb(136, 136, 136);font-size: 14px;\">\u8fd9\u5e45\u56fe\u5c55\u793a\u4e86\u8f6c\u5f55\u56e0\u5b50SREBP\u3001PPAR-\u03b1\u4e0e\u8c03\u63a7\u8102\u80aa\u4ee3\u8c22\u7684\u751f\u7269\u949f\u6709\u5173\u8054\uff1a\u201c\u540e\u8f6e\u201dSREBP\uff0c\u76f4\u63a5\u9a71\u52a8\u8102\u80aa\u7684\u5408\u6210\uff0c\u901a\u8fc7\u201c\u524d\u8f6e\u201dPPAR-\u03b1\u95f4\u63a5\u9a71\u52a8\u8102\u80aa\u71c3\u70e7\u7684\u540c\u6b65\u53d8\u5316\uff1b\u5c0f\u9f20\u624b\u4e2d\u7684\u201c\u6c34\u74f6\u201d\u4e2d\u542b\u6709\u4e00\u4e2aPPAR-\u03b1\u7684\u6fc0\u52a8\u914d\u4f53\uff0c\u8d1f\u8d23\u589e\u52a0PPAR-\u03b1\u7684\u9a71\u52a8\u529b\u3002\u56fe\u7247\u6765\u6e90\uff1aAnnie Spikes, Dongyin Guan and Mitchell A. Lazar, Perelman School of Medicine, University of Pennsylvania; Cell<\/span><\/p>\n<p style=\"line-height: 1.75em;\"><\/p>\n<p style=\"line-height: 1.75em;text-align: justify;\">7\u670826\u65e5\uff0c\u6765\u81ea\u4e8e\u5bbe\u5915\u6cd5\u5c3c\u4e9a\u5927\u5b66Perelman\u533b\u5b66\u9662\u7684\u79d1\u5b66\u5bb6\u4eec\u5728\u300aCell\u300b\u671f\u520a\u5728\u7ebf\u53d1\u8868\u4e86\u8fd9\u4e00\u7bc7\u9898\u4e3a\u201cDiet-Induced Circadian Enhancer Remodeling Synchronizes Opposing Hepatic Lipid Metabolic Processes\u201d\u7684\u7814\u7a76\u3002<\/p>\n<p><\/p>\n<p style=\"line-height: 1.75em;text-align: justify;\">\u4ed6\u4eec\u53d1\u73b0\uff0c\u968f\u7740\u809d\u810f\u8102\u80aa\u542b\u91cf\u7684\u589e\u52a0\uff0c\u8eab\u4f53\u71c3\u70e7\u8102\u80aa\u7684\u80fd\u529b\u4e5f\u4f1a\u4e0a\u8c03\u3002\u800c\u4e14\uff0c\u8fd9\u4e9b\u76f8\u53cd\u7684\u751f\u7406\u8fc7\u7a0b\u4f1a\u5728\u6bcf\u5929\u4e0b\u53485\u70b9\u8fbe\u5230\u5cf0\u503c\u3002\u8fd9\u610f\u5473\u7740\uff0c\u66b4\u996e\u66b4\u98df\u3001\u751f\u7269\u949f\u3001\u809d\u810f\u8102\u80aa\u7d2f\u79ef\u4e4b\u95f4\u5b58\u5728\u4e00\u79cd\u610f\u6599\u4e4b\u5916\u7684\u8054\u7cfb\u3002<\/p>\n<p style=\"line-height: 1.75em;\"><\/p>\n<p style=\"line-height: 1.75em;text-align: center;\"><img class=\"\"     style=\"margin-top: 6px;margin-bottom: 6px;border-width: 0px;border-style: none;border-color: initial;vertical-align: middle;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/08\/beepress5-1533788225.jpeg\" alt=\"Cell\uff1a\u4e0b\u53485\u70b9\uff0c\u751f\u7269\u949f\u4fc3\u8fdb\u8102\u80aa\u71c3\u70e7\u7684\u201c\u9ec4\u91d1\u671f\u201d\" title=\"Cell\uff1a\u4e0b\u53485\u70b9\uff0c\u751f\u7269\u949f\u4fc3\u8fdb\u8102\u80aa\u71c3\u70e7\u7684\u201c\u9ec4\u91d1\u671f\u201d\"><\/p>\n<section class=\"\"  style=\"white-space: normal;max-width: 100%;color: rgb(51, 51, 51);\">\n<section style=\"margin: 10px auto;max-width: 100%;text-align: center;box-sizing: border-box !important;word-wrap: break-word !important;\">\n<section style=\"margin-bottom: 3px;margin-left: 33px;max-width: 100%;font-size: 0px;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 16px;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"margin-bottom: 10px;max-width: 100%;width: 6px;height: 6px;display: inline-block;color: rgb(255, 255, 255);background-color: rgb(172, 29, 16);box-sizing: border-box !important;word-wrap: break-word !important;\"><\/span><span style=\"max-width: 100%;display: inline-block;width: 10px;height: 10px;opacity: 0.6;color: rgb(255, 255, 255);background-color: rgb(172, 29, 16);box-sizing: border-box !important;word-wrap: break-word !important;\"><\/span>&nbsp;&nbsp;&nbsp;<\/span><\/section>\n<section style=\"margin-top: -2px;max-width: 100%;font-size: 0px;box-sizing: border-box !important;word-wrap: break-word !important;\">\n<section style=\"max-width: 100%;display: inline-block;width: 15px;height: 15px;border-width: 1px;border-style: solid;border-color: white;opacity: 0.9;vertical-align: bottom;color: rgb(255, 255, 255);background-color: rgb(172, 29, 16);box-sizing: border-box !important;word-wrap: break-word !important;\"><\/section>\n<section style=\"max-width: 100%;display: inline-block;border-width: 1px;border-style: solid;border-color: rgb(255, 255, 255);width: 30px;height: 30px;line-height: 30px;vertical-align: top;color: rgb(255, 255, 255);background-color: rgb(172, 29, 16);box-sizing: border-box !important;word-wrap: break-word !important;\">\n<p class=\"\" style=\"margin-right: auto;margin-left: auto;max-width: 100%;min-height: 1em;white-space: pre-wrap;min-width: 1px;font-size: 16px;box-sizing: border-box !important;word-wrap: break-word !important;\">01<\/p>\n<\/section>\n<section style=\"max-width: 100%;display: inline-block;width: 15px;height: 15px;border-width: 1px;border-style: solid;border-color: white;opacity: 0.9;vertical-align: top;color: rgb(255, 255, 255);background-color: rgb(172, 29, 16);box-sizing: border-box !important;word-wrap: break-word !important;\"><\/section>\n<\/section>\n<section style=\"margin-top: 3px;margin-left: -33px;max-width: 100%;font-size: 0px;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 16px;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;display: inline-block;width: 10px;height: 10px;opacity: 0.6;color: rgb(255, 255, 255);background-color: rgb(172, 29, 16);box-sizing: border-box !important;word-wrap: break-word !important;\"><\/span><span style=\"margin-bottom: -10px;max-width: 100%;width: 6px;height: 6px;display: inline-block;color: rgb(255, 255, 255);background-color: rgb(172, 29, 16);box-sizing: border-box !important;word-wrap: break-word !important;\"><\/span>&nbsp; &nbsp;<\/span><\/section>\n<\/section>\n<\/section>\n<p style=\"white-space: normal;max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);text-align: center;\"><span style=\"max-width: 100%;font-size: 16px;color: rgb(123, 12, 0);box-sizing: border-box !important;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;text-align: justify;box-sizing: border-box !important;word-wrap: break-word !important;\">\u80a5\u80d6\u3001\u751f\u7269\u949f<\/span><\/strong><\/span><\/p>\n<p style=\"white-space: normal;max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);text-align: center;\"><\/p>\n<p style=\"line-height: 1.75em;text-align: justify;\">\u201c\u6211\u4eec\u77e5\u9053\uff0c\u80a5\u80d6\u4f1a\u5bfc\u81f4\u8102\u80aa\u5728\u809d\u810f\u4e2d\u7d2f\u79ef\uff0c\u4ece\u800c\u5bfc\u81f4\u708e\u75c7\u751a\u81f3\u4e8e\u589e\u52a0\u809d\u708e\u3001\u809d\u8870\u7aed\u3001\u809d\u764c\u98ce\u9669\u3002\u201dPeen\u7cd6\u5c3f\u75c5\u3001\u80a5\u80d6\u548c\u65b0\u9648\u4ee3\u8c22\u7814\u7a76\u6240\u4e3b\u4efb Mitchell Lazar\u8868\u793a\uff0c\u201c\u8fd9\u80cc\u540e\u5173\u8054\u7740\u5de8\u5927\u7684\u5065\u5eb7\u95ee\u9898\u3002\u201d<\/p>\n<p><\/p>\n<p style=\"line-height: 1.75em;text-align: justify;\">\u5c3d\u7ba1\u5168\u7403\u670910\u4ebf\u4eba\u53d7\u5230\u8425\u517b\u4e0d\u826f\u7684\u4e0d\u5229\u5f71\u54cd\uff0c\u4f46\u662f\u4f9d\u7136\u670910\u4ebf\u4eba\u56e0\u4e3a\u6444\u5165\u8fc7\u591a\u7684\u70ed\u91cf\uff0c\u5373\u201c\u8425\u517b\u8fc7\u5269\u201d\u800c\u5bfc\u81f4\u80a5\u80d6\u548c\u5176\u4ed6\u4ee3\u8c22\u7d0a\u4e71\uff0c\u5305\u62ec2\u578b\u7cd6\u5c3f\u75c5\u3001\u5fc3\u8840\u7ba1\u75be\u75c5\u3001\u8102\u80aa\u809d\u3001\u9ad8\u8840\u538b\u548c\u764c\u75c7\u3002<\/p>\n<p><\/p>\n<p style=\"line-height: 1.75em;text-align: justify;\">\u8102\u80aa\u4ea7\u751f\u548c\u71c3\u70e7\u6240\u9075\u5faa\u7684\u751f\u7269\u949f\u662f\u4e00\u4e2a\u7ea624\u5c0f\u65f6\u7684\u751f\u7406\u5faa\u73af\u8fc7\u7a0b\u3002\u5728\u5206\u5b50\u6c34\u5e73\u4e2d\uff0c\u8fd9\u4e9b\u5faa\u73af\u6d89\u53ca\u5230\u751f\u7269\u949f\u6838\u5fc3\u86cb\u767d\uff08\u5728\u8eab\u4f53\u51e0\u4e4e\u6240\u6709\u7ec6\u80de\u90fd\u6709\u8868\u8fbe\uff09\u7684\u8c03\u63a7\u56de\u8def\u3002\u8fd9\u4e00\u8282\u5f8b\u901a\u8fc7\u6574\u5408\u73af\u5883\u523a\u6fc0\u3001\u9057\u4f20\u4fe1\u606f\uff0c\u4ee5\u4e00\u79cd\u7ec4\u7ec7\u7279\u6709\u7684\u65b9\u5f0f\u63a7\u5236\u57fa\u56e0\u6709\u8282\u594f\u7684\u8868\u8fbe\u3002<\/p>\n<p><\/p>\n<p style=\"line-height: 1.75em;text-align: justify;\">\u8425\u517b\u8fc7\u5269\u4f1a\u7834\u574f\u751f\u7269\u949f\uff0c\u8fdb\u800c\u5f71\u54cd\u4ee3\u8c22\u7d0a\u4e71\u3002\u4e86\u89e3\u5f71\u54cd\u663c\u591c\u8282\u5f8b\u4e0e\u4ee3\u8c22\u7d0a\u4e71\u4e4b\u95f4\u5173\u8054\u7684\u673a\u5236\uff0c\u5bf9\u4e8e\u5236\u5b9a\u6cbb\u7597\u80a5\u80d6\u76f8\u5173\u75be\u75c5\u5bf9\u7b56\u5f88\u6709\u5fc5\u8981\u3002<\/p>\n<section class=\"\"  style=\"white-space: normal;max-width: 100%;color: rgb(51, 51, 51);\">\n<section style=\"margin: 10px auto;max-width: 100%;text-align: center;box-sizing: border-box !important;word-wrap: break-word !important;\">\n<section style=\"margin-bottom: 3px;margin-left: 33px;max-width: 100%;font-size: 0px;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 16px;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"margin-bottom: 10px;max-width: 100%;width: 6px;height: 6px;display: inline-block;color: rgb(255, 255, 255);background-color: rgb(172, 29, 16);box-sizing: border-box !important;word-wrap: break-word !important;\"><\/span><span style=\"max-width: 100%;display: inline-block;width: 10px;height: 10px;opacity: 0.6;color: rgb(255, 255, 255);background-color: rgb(172, 29, 16);box-sizing: border-box !important;word-wrap: break-word !important;\"><\/span>&nbsp;&nbsp;&nbsp;<\/span><\/section>\n<section style=\"margin-top: -2px;max-width: 100%;font-size: 0px;box-sizing: border-box !important;word-wrap: break-word !important;\">\n<section style=\"max-width: 100%;display: inline-block;width: 15px;height: 15px;border-width: 1px;border-style: solid;border-color: white;opacity: 0.9;vertical-align: bottom;color: rgb(255, 255, 255);background-color: rgb(172, 29, 16);box-sizing: border-box !important;word-wrap: break-word !important;\"><\/section>\n<section style=\"max-width: 100%;display: inline-block;border-width: 1px;border-style: solid;border-color: rgb(255, 255, 255);width: 30px;height: 30px;line-height: 30px;vertical-align: top;color: rgb(255, 255, 255);background-color: rgb(172, 29, 16);box-sizing: border-box !important;word-wrap: break-word !important;\">\n<p class=\"\" style=\"margin-right: auto;margin-left: auto;max-width: 100%;min-height: 1em;white-space: pre-wrap;min-width: 1px;font-size: 16px;box-sizing: border-box !important;word-wrap: break-word !important;\">02<\/p>\n<\/section>\n<section style=\"max-width: 100%;display: inline-block;width: 15px;height: 15px;border-width: 1px;border-style: solid;border-color: white;opacity: 0.9;vertical-align: top;color: rgb(255, 255, 255);background-color: rgb(172, 29, 16);box-sizing: border-box !important;word-wrap: break-word !important;\"><\/section>\n<\/section>\n<section style=\"margin-top: 3px;margin-left: -33px;max-width: 100%;font-size: 0px;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 16px;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;display: inline-block;width: 10px;height: 10px;opacity: 0.6;color: rgb(255, 255, 255);background-color: rgb(172, 29, 16);box-sizing: border-box !important;word-wrap: break-word !important;\"><\/span><span style=\"margin-bottom: -10px;max-width: 100%;width: 6px;height: 6px;display: inline-block;color: rgb(255, 255, 255);background-color: rgb(172, 29, 16);box-sizing: border-box !important;word-wrap: break-word !important;\"><\/span>&nbsp; &nbsp;<\/span><\/section>\n<\/section>\n<\/section>\n<p style=\"white-space: normal;max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);text-align: center;\"><span style=\"max-width: 100%;font-size: 16px;color: rgb(123, 12, 0);box-sizing: border-box !important;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;text-align: justify;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"text-align: justify;\">\u996e\u98df\u5f15\u53d1\u7684\u80a5\u80d6\u4f1a\u91cd\u5851\u809d\u810f\u751f\u7269\u949f<\/span><\/span><\/strong><\/span><\/p>\n<p><\/p>\n<p style=\"line-height: 1.75em;text-align: justify;\">\u201c\u6211\u4eec\u63a8\u6d4b\uff0c\u996e\u98df\u8bf1\u5bfc\u7684\u751f\u7269\u949f\u53d8\u5316\uff08\u53cd\u5bf9\u8102\u80aa\u4ee3\u8c22\u8fc7\u7a0b\uff09\u662f\u4e3a\u4e86\u5e94\u5bf9\u8425\u517b\u8fc7\u5269\uff0c\u786e\u4fdd\u8102\u80aa\u71c3\u70e7\u7387\u8d85\u8fc7\u8102\u80aa\u7d2f\u79ef\u7387\u3002\u201d\u7b2c\u4e00\u4f5c\u8005Dongyin Guan\u535a\u58eb\u8868\u793a\u9053\u3002<\/p>\n<p><\/p>\n<p style=\"line-height: 1.75em;text-align: justify;\">\u8fd9\u4e0024\u5c0f\u65f6\u7684\u751f\u7269\u949f\u4e3a\u201c\u65f6\u95f4\u7597\u6cd5\u201d\u7684\u53ef\u884c\u6027\u63d0\u4f9b\u4e86\u601d\u8def\u2014\u2014\u5728\u836f\u7269\u6700\u6709\u6548\u3001\u8010\u53d7\u6700\u5f3a\u7684\u65f6\u95f4\u7528\u836f\uff0c\u63d0\u9ad8\u7597\u6548\u3001\u51cf\u5c11\u6bd2\u6027\u3002\u7814\u7a76\u56e2\u961f\u53d1\u73b0\uff0c\u8102\u80aa\u71c3\u70e7\u7684\u8282\u5f8b\u662f\u7531PPAR-\u03b1\u86cb\u767d\u6240\u8c03\u63a7\u7684\u3002<\/p>\n<p style=\"line-height: 1.75em;\"><\/p>\n<p style=\"line-height: 1.75em;text-align: justify;\">\u800c\u4e14\uff0cPPAR-\u03b1\u86cb\u767d\u7684\u6fc0\u6d3b\u4f9d\u8d56\u4e8eSREBP1\u86cb\u767d\uff0c\u540e\u8005\u76f4\u63a5\u8d1f\u8d23\u8102\u80aa\u7684\u5408\u6210\u3002\u8fd9\u610f\u5473\u7740\uff0c\u5f53\u201c\u8425\u517b\u8fc7\u5ea6\u201d\u5f15\u53d1\u8102\u80aa\u5806\u79ef\u65f6\uff0c\u751f\u7269\u949f\u4f1a\u52aa\u529b\u9a71\u52a8\u8102\u80aa\u6d88\u8017\u3002<\/p>\n<p style=\"line-height: 1.75em;\"><\/p>\n<p style=\"line-height: 1.75em;text-align: center;\"><\/p>\n<p style=\"line-height: 1.75em;text-align: center;\"><span style=\"color: rgb(136, 136, 136);\">\u56fe\u7247\u6765\u6e90\uff1aCell<\/span><\/p>\n<section class=\"\"  style=\"white-space: normal;max-width: 100%;color: rgb(51, 51, 51);\">\n<section style=\"margin: 10px auto;max-width: 100%;text-align: center;box-sizing: border-box !important;word-wrap: break-word !important;\">\n<section style=\"margin-bottom: 3px;margin-left: 33px;max-width: 100%;font-size: 0px;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 16px;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"margin-bottom: 10px;max-width: 100%;width: 6px;height: 6px;display: inline-block;color: rgb(255, 255, 255);background-color: rgb(172, 29, 16);box-sizing: border-box !important;word-wrap: break-word !important;\"><\/span><span style=\"max-width: 100%;display: inline-block;width: 10px;height: 10px;opacity: 0.6;color: rgb(255, 255, 255);background-color: rgb(172, 29, 16);box-sizing: border-box !important;word-wrap: break-word !important;\"><\/span>&nbsp;&nbsp;&nbsp;<\/span><\/section>\n<section style=\"margin-top: -2px;max-width: 100%;font-size: 0px;box-sizing: border-box !important;word-wrap: break-word !important;\">\n<section style=\"max-width: 100%;display: inline-block;width: 15px;height: 15px;border-width: 1px;border-style: solid;border-color: white;opacity: 0.9;vertical-align: bottom;color: rgb(255, 255, 255);background-color: rgb(172, 29, 16);box-sizing: border-box !important;word-wrap: break-word !important;\"><\/section>\n<section style=\"max-width: 100%;display: inline-block;border-width: 1px;border-style: solid;border-color: rgb(255, 255, 255);width: 30px;height: 30px;line-height: 30px;vertical-align: top;color: rgb(255, 255, 255);background-color: rgb(172, 29, 16);box-sizing: border-box !important;word-wrap: break-word !important;\">\n<p class=\"\" style=\"margin-right: auto;margin-left: auto;max-width: 100%;min-height: 1em;white-space: pre-wrap;min-width: 1px;font-size: 16px;box-sizing: border-box !important;word-wrap: break-word !important;\">03<\/p>\n<\/section>\n<section style=\"max-width: 100%;display: inline-block;width: 15px;height: 15px;border-width: 1px;border-style: solid;border-color: white;opacity: 0.9;vertical-align: top;color: rgb(255, 255, 255);background-color: rgb(172, 29, 16);box-sizing: border-box !important;word-wrap: break-word !important;\"><\/section>\n<\/section>\n<section style=\"margin-top: 3px;margin-left: -33px;max-width: 100%;font-size: 0px;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 16px;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;display: inline-block;width: 10px;height: 10px;opacity: 0.6;color: rgb(255, 255, 255);background-color: rgb(172, 29, 16);box-sizing: border-box !important;word-wrap: break-word !important;\"><\/span><span style=\"margin-bottom: -10px;max-width: 100%;width: 6px;height: 6px;display: inline-block;color: rgb(255, 255, 255);background-color: rgb(172, 29, 16);box-sizing: border-box !important;word-wrap: break-word !important;\"><\/span>&nbsp; &nbsp;<\/span><\/section>\n<\/section>\n<\/section>\n<p style=\"white-space: normal;max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);text-align: center;\"><span style=\"max-width: 100%;font-size: 16px;color: rgb(123, 12, 0);box-sizing: border-box !important;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;text-align: justify;box-sizing: border-box !important;word-wrap: break-word !important;\">\u5e94\u7528\u4ef7\u503c<\/span><\/strong><\/span><\/p>\n<p style=\"line-height: 1.75em;\"><\/p>\n<p style=\"line-height: 1.75em;text-align: justify;\">PPAR-\u03b1\u662f\u4e00\u79cd\u8d1d\u7279\u7c7b\u836f\u7269\uff08\u4e00\u7c7b\u964d\u7518\u6cb9\u4e09\u916f\u548c\u964d\u80c6\u56fa\u9187\u836f\u7269\uff09\u7684\u4f5c\u7528\u9776\u6807\u3002\u4e0b\u53485\u70b9\u5de6\u53f3\uff0c\u809d\u810f\u4e2d\u7684PPAR-\u03b1\u86cb\u767d\u542b\u91cf\u8fbe\u5230\u5cf0\u503c\u3002Mitchell Lazar\u597d\u5947\uff0c\u5f53PPAR-\u03b1\u86cb\u767d\u8fbe\u5230\u6700\u9ad8\u6c34\u5e73\u65f6\uff0c\u9776\u5411PPAR-\u03b1\u7684\u77ed\u6548\u836f\u7269\u662f\u5426\u6709\u597d\u5904\uff1f<\/p>\n<p><\/p>\n<p style=\"line-height: 1.75em;text-align: justify;\">\u4ed6\u4eec\u53d1\u73b0\uff0c\u76f8\u6bd4\u4e8e\u65e9\u6668\uff0c\u4e00\u79cd\u77ed\u6548\u7684PPAR-\u03b1\u836f\u7269\u5728\u4e0b\u5348\u7ed9\u836f\u66f4\u80fd\u51cf\u5c11\u809d\u810f\u8102\u80aa\u7d2f\u79ef\uff0c\u8fd9\u7c7b\u4f3c\u4e8e\u4ed6\u6c40\u7c7b\u836f\u7269\uff08\u964d\u80c6\u56fa\u9187\u836f\u7269\uff09\u5728\u5c31\u5bdd\u65f6\u95f4\u670d\u7528\u4e00\u6837\u3002<\/p>\n<p><\/p>\n<p style=\"line-height: 1.75em;text-align: justify;\">\u201c\u6211\u4eec\u7684\u7ed3\u679c\u652f\u6301\uff0c\u7531\u4e8ePPAR-\u03b1\u8282\u5f8b\uff0c\u5728\u7279\u5b9a\u7684\u65f6\u95f4\u964d\u4f4e\u809d\u810f\u3001\u8840\u6db2\u8102\u80aa\u6c34\u5e73\u7684\u836f\u7269\u53ef\u80fd\u66f4\u6709\u6548\u3002\u201d Lazar\u8868\u793a\uff0c\u201c\u9075\u5faa\u8fd9\u4e00\u539f\u5219\u66f4\u5bb9\u6613\u6cbb\u7597\u809d\u810f\u4ee3\u8c22\u7c7b\u75be\u75c5\uff0c\u4ece\u800c\u8ba9\u60a3\u8005\u53d7\u76ca\u66f4\u5927\u3002\u201d<\/p>\n<p style=\"line-height: 1.75em;\"><\/p>\n<p style=\"line-height: 1.75em;text-align: right;\"><strong>\u8d23\u7f16\uff1a\u98ce\u94c3<\/strong><\/p>\n<section  class=\"\" style=\"max-width: 100%;color: rgb(51, 51, 51);\">\n<section  style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\">\n<section  class=\"\" style=\"max-width: 100%;line-height: 28.4444px;font-family: \u5fae\u8f6f\u96c5\u9ed1;border-width: 0px;border-style: none;border-color: initial;box-sizing: border-box !important;word-wrap: break-word !important;overflow-wrap: break-word !important;\">\n<section  style=\"margin: 1em auto;max-width: 100%;border-width: 0px;border-style: none;border-color: initial;text-align: center;width: 941px;box-sizing: border-box !important;word-wrap: break-word !important;overflow-wrap: break-word !important;\"><span class=\"\"  style=\"max-width: 100%;width: 941px;border-bottom: 1px solid rgb(172, 29, 16);border-top-color: rgb(172, 29, 16);border-right-color: rgb(172, 29, 16);border-left-color: rgb(172, 29, 16);display: inline-block;box-sizing: border-box !important;word-wrap: break-word !important;overflow-wrap: break-word !important;\"><\/p>\n<section class=\"\" style=\"margin-bottom: -3px;padding-top: 5px;padding-right: 10px;padding-left: 10px;max-width: 100%;display: inline-block;min-height: 32px;border-bottom: 5px solid rgb(172, 29, 16);font-size: 20px;color: rgb(121, 121, 121);box-sizing: border-box !important;word-wrap: break-word !important;overflow-wrap: break-word !important;\">\n<p class=\"\" style=\"margin-top: 5px;margin-bottom: 5px;max-width: 100%;min-height: 1em;line-height: 1.6em;font-size: 16px;box-sizing: border-box !important;word-wrap: break-word !important;overflow-wrap: break-word !important;\">End<\/p>\n<\/section>\n<p><\/span><\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<p class=\"\" style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><strong class=\"\" style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"><span class=\"\" style=\"max-width: 100%;font-size: 12px;box-sizing: border-box !important;word-wrap: break-word !important;\">\u53c2\u8003\u8d44\u6599\uff1a<\/span><\/strong><span style=\"max-width: 100%;font-size: 12px;box-sizing: border-box !important;word-wrap: break-word !important;\">1\uff09<span style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\">Fat production and burning are synchronized in livers of mice with obesity<\/span><\/span><\/p>\n<p class=\"\" style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"><\/p>\n<section  class=\"\" style=\"max-width: 100%;box-sizing: border-box;letter-spacing: 0.544px;text-align: justify;white-space: normal;background-color: rgb(255, 255, 255);font-size: 16px;color: rgb(62, 62, 62);line-height: 25.6px;font-family: \u5fae\u8f6f\u96c5\u9ed1;border-width: 0px;border-style: none;word-wrap: break-word !important;overflow-wrap: break-word !important;\">\n<section class=\"\"  style=\"padding: 2px;max-width: 100%;box-sizing: border-box;border-width: 1px;border-style: dotted;border-color: rgb(218, 98, 71);word-wrap: break-word !important;overflow-wrap: break-word !important;\">\n<section class=\"\" style=\"margin: 5px auto;max-width: 100%;box-sizing: border-box;border-width: 0px;border-style: none;word-wrap: break-word !important;overflow-wrap: break-word !important;\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;height: 25px;color: inherit;word-wrap: break-word !important;overflow-wrap: break-word !important;\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;height: 25px;width: 50px;float: left;border-top: 2px solid rgb(172, 29, 16);border-right-color: rgb(172, 29, 16);border-bottom-color: rgb(172, 29, 16);border-left: 2px solid rgb(172, 29, 16);color: inherit;word-wrap: break-word !important;overflow-wrap: break-word !important;\"><\/section>\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;display: inline-block;color: rgb(172, 29, 16);clear: both;border-color: rgb(172, 29, 16);word-wrap: break-word !important;overflow-wrap: break-word !important;\"><\/section>\n<\/section>\n<section class=\"\"  style=\"margin: -0.8em 0.3em;padding: 0.8em;max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;color: inherit;overflow-wrap: break-word !important;\">\n<p class=\"\" style=\"max-width: 100%;min-height: 1em;overflow-wrap: break-word;color: rgb(51, 51, 51);font-size: 1em;line-height: 1.75em;word-break: break-all;box-sizing: border-box !important;word-wrap: break-word !important;\"><span class=\"\" style=\"max-width: 100%;color: rgb(0, 0, 0);line-height: 22.4px;font-size: 14px;box-sizing: border-box !important;word-wrap: break-word !important;overflow-wrap: break-word !important;\">\u672c\u6587\u7cfb\u751f\u7269\u63a2\u7d22\u539f\u521b\uff0c\u6b22\u8fce\u4e2a\u4eba\u8f6c\u53d1\u5206\u4eab\u3002\u5176\u4ed6\u4efb\u4f55\u5a92\u4f53\u3001\u7f51\u7ad9\u5982\u9700\u8f6c\u8f7d\uff0c\u987b\u5728\u6b63\u6587\u524d\u6ce8\u660e\u6765\u6e90\u751f\u7269\u63a2\u7d22\u3002<\/span><\/p>\n<\/section>\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;height: 25px;color: inherit;word-wrap: break-word !important;overflow-wrap: break-word !important;\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;height: 25px;width: 50px;float: right;border-bottom: 2px solid rgb(172, 29, 16);border-top-color: rgb(172, 29, 16);border-right: 2px solid rgb(172, 29, 16);border-left-color: rgb(172, 29, 16);color: inherit;word-wrap: break-word !important;overflow-wrap: break-word !important;\"><\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<p class=\"\" style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><img class=\"\"       style=\"box-sizing: border-box !important;word-wrap: break-word !important;visibility: visible !important;width: auto !important;\" width=\"auto\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/08\/beepress0-1533788225.png\" alt=\"Cell\uff1a\u4e0b\u53485\u70b9\uff0c\u751f\u7269\u949f\u4fc3\u8fdb\u8102\u80aa\u71c3\u70e7\u7684\u201c\u9ec4\u91d1\u671f\u201d\" title=\"Cell\uff1a\u4e0b\u53485\u70b9\uff0c\u751f\u7269\u949f\u4fc3\u8fdb\u8102\u80aa\u71c3\u70e7\u7684\u201c\u9ec4\u91d1\u671f\u201d\"><\/p>\n<blockquote class='keep-source'>\n<p>\u59cb\u53d1\u4e8e\u5fae\u4fe1\u516c\u4f17\u53f7\uff1a                         \u751f\u7269\u63a2\u7d22                      <\/p>\n<\/blockquote>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>\u5f88\u591a\u4eba\u4e4b\u6240\u4ee5\u80a5\u80d6\u4e0e\u201c\u8425\u517b\u8fc7\u5269\u201d\u6709\u5173\u8054\uff0c\u8fd9\u4e00\u996e\u98df\u56e0\u7d20\u4f1a\u5f71\u54cd\u751f\u7269\u949f\uff0c\u4f46\u662f\u80cc\u540e\u7684\u673a\u5236\u5374\u4e0d\u6e05\u6670\u3002\u73b0\u5728\uff0c\u6700\u65b0\u4e00\u9879\u7814\u7a76\u63ed\u793a [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":31550,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[2],"tags":[],"_links":{"self":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/31549"}],"collection":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/comments?post=31549"}],"version-history":[{"count":1,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/31549\/revisions"}],"predecessor-version":[{"id":31559,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/31549\/revisions\/31559"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/media\/31550"}],"wp:attachment":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/media?parent=31549"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/categories?post=31549"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/tags?post=31549"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}