{"id":31860,"date":"2018-08-01T01:00:00","date_gmt":"2018-08-09T04:19:00","guid":{"rendered":"http:\/\/www.05921.net\/index.php\/2018\/08\/09\/%e7%8c%8e%e8%8d%af%e4%ba%ba%e9%a3%8e%e9%87%87%e4%b9%8b%e5%a4%8d%e6%97%a6%e7%af%87%ef%bc%9a%e6%9d%a8%e9%9d%92%e6%95%99%e6%8e%88\/"},"modified":"2018-08-09T12:19:04","modified_gmt":"2018-08-09T04:19:04","slug":"%e7%8c%8e%e8%8d%af%e4%ba%ba%e9%a3%8e%e9%87%87%e4%b9%8b%e5%a4%8d%e6%97%a6%e7%af%87%ef%bc%9a%e6%9d%a8%e9%9d%92%e6%95%99%e6%8e%88","status":"publish","type":"post","link":"https:\/\/www.05921.net\/index.php\/31860\/","title":{"rendered":"\u730e\u836f\u4eba\u98ce\u91c7\u4e4b\u590d\u65e6\u7bc7\uff1a\u6768\u9752\u6559\u6388"},"content":{"rendered":"<div class=\"bpp-post-content\">\n<section style=\"box-sizing: border-box;\">\n<section class=\"V5\" style=\"box-sizing: border-box;\" >\n<section style=\"text-align: center;margin: 10px 0%;box-sizing: border-box;\">\n<section style=\"display: inline-block;vertical-align: top;width: 10%;box-sizing: border-box;\">\n<section class=\"V5\" style=\"box-sizing: border-box;\" >\n<section style=\"margin-right: 0%;margin-left: 0%;box-sizing: border-box;\">\n<section style=\"width: 2em;margin: auto;display: inline-block;box-sizing: border-box;\">\n<section style=\"display: inline-block;vertical-align: top;padding-top: 3px;padding-bottom: 3px;background-color: rgb(162, 48, 38);color: rgb(255, 255, 255);font-size: 17px;box-sizing: border-box;\">\n<p style=\"box-sizing: border-box;\">\u524d\u8a00<\/p>\n<\/section>\n<section style=\"display: inline-block;vertical-align: top;border-left: 1em solid rgb(162, 48, 38);border-top: 0.5em solid rgb(162, 48, 38);border-right: 1em solid transparent !important;border-bottom: 0.5em solid transparent !important;box-sizing: border-box;\"><\/section>\n<section style=\"display: inline-block;vertical-align: top;margin-top: -10px;font-size: 18px;box-sizing: border-box;\">\n<p style=\"box-sizing: border-box;\"><br style=\"box-sizing: border-box;\"  \/><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"display: inline-block;vertical-align: top;width: 88%;border-left: 3px solid rgb(162, 48, 38);border-bottom-left-radius: 0px;padding-right: 10px;padding-left: 10px;box-sizing: border-box;\">\n<section class=\"V5\" style=\"box-sizing: border-box;\" >\n<section style=\"box-sizing: border-box;\">\n<section style=\"text-align: left;color: rgb(162, 48, 38);box-sizing: border-box;\">\n<p style=\"box-sizing: border-box;\"><strong style=\"box-sizing: border-box;\">SCiDDD\u730e\u836f\u4eba\u98ce\u91c7<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"V5\" style=\"box-sizing: border-box;\" >\n<section style=\"box-sizing: border-box;\">\n<section style=\"text-align: justify;font-size: 14px;line-height: 1.8;box-sizing: border-box;\">\n<p style=\"white-space: normal;box-sizing: 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class=\"V5\" style=\"box-sizing: border-box;\" >\n<section style=\"box-sizing: border-box;\">\n<section style=\"box-sizing: border-box;\">\n<p style=\"box-sizing: border-box;\"><br style=\"box-sizing: border-box;\"  \/><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"V5\" style=\"box-sizing: border-box;\" >\n<section style=\"box-sizing: border-box;\">\n<section style=\"box-sizing: border-box;\">\n<section class=\"Powered-by-XIUMI V5\"  style=\"white-space: normal;box-sizing: border-box;\">\n<section class=\"\" style=\"box-sizing: border-box;\">\n<section class=\"\" style=\"box-sizing: border-box;\">\n<section class=\"Powered-by-XIUMI V5\"  style=\"background-color: rgb(255, 255, 255);box-sizing: border-box;\">\n<section class=\"\" style=\"margin-top: 10px;margin-bottom: 5px;box-sizing: border-box;\">\n<section class=\"\" style=\"display: inline-block;width: 558.4px;vertical-align: top;box-sizing: border-box;\">\n<section class=\"Powered-by-XIUMI V5\"  style=\"box-sizing: border-box;\">\n<section class=\"\" style=\"box-sizing: border-box;\">\n<section class=\"\" style=\"text-align: center;font-size: 20px;color: rgb(11, 11, 11);letter-spacing: 2px;box-sizing: border-box;\">\n<p style=\"box-sizing: border-box;\"><strong style=\"box-sizing: border-box;\">\u730e\u836f\u4eba\u98ce\u91c7\u4e4b\u590d\u65e6\u7bc7<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"Powered-by-XIUMI V5\"  style=\"box-sizing: border-box;\">\n<section class=\"\" style=\"margin-bottom: 10px;text-align: center;box-sizing: border-box;\">\n<section class=\"\" style=\"border-top: 2px solid rgb(184, 54, 33);width: 1.2em;display: inline-block;vertical-align: middle;border-right-color: rgb(184, 54, 33);border-bottom-color: rgb(184, 54, 33);border-left-color: rgb(184, 54, 33);box-sizing: border-box;\"><\/section>\n<section class=\"\" style=\"margin-right: -1.2em;margin-left: -1.2em;padding: 3px 1.5em;display: inline-block;vertical-align: middle;color: rgb(38, 43, 44);box-sizing: border-box;\">\n<p style=\"box-sizing: border-box;\">\u6768\u9752\u6559\u6388<\/p>\n<\/section>\n<section class=\"\" style=\"border-top: 2px solid rgb(184, 54, 33);width: 1.2em;display: inline-block;vertical-align: middle;border-right-color: rgb(184, 54, 33);border-bottom-color: rgb(184, 54, 33);border-left-color: rgb(184, 54, 33);box-sizing: border-box;\"><\/section>\n<\/section>\n<\/section>\n<section class=\"Powered-by-XIUMI V5\"  style=\"box-sizing: border-box;\">\n<section class=\"\" style=\"margin-top: -20px;opacity: 0.22;box-sizing: border-box;\">\n<section class=\"\" style=\"font-size: 28px;color: rgb(202, 198, 198);box-sizing: border-box;\">\n<p style=\"box-sizing: border-box;\"><br style=\"box-sizing: border-box;\"  \/><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"Powered-by-XIUMI V5\"  style=\"background-color: rgb(255, 255, 255);box-sizing: border-box;\">\n<section class=\"\" style=\"margin-top: -120px;margin-bottom: 10px;text-align: right;font-size: 5px;opacity: 0.16;transform: translate3d(-40px, 0px, 0px);box-sizing: border-box;\">\n<section class=\"\" style=\"max-width: 100%;vertical-align: middle;display: inline-block;width: 139.6px;box-shadow: rgba(0, 0, 0, 0) 0px 0px 0px;box-sizing: border-box;overflow: hidden !important;\"><img class=\"\"          style=\"height: 81px;vertical-align: middle;width: 132px;box-sizing: border-box;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/08\/beepress6-1533788341.jpg\" alt=\"\u730e\u836f\u4eba\u98ce\u91c7\u4e4b\u590d\u65e6\u7bc7\uff1a\u6768\u9752\u6559\u6388\" title=\"\u730e\u836f\u4eba\u98ce\u91c7\u4e4b\u590d\u65e6\u7bc7\uff1a\u6768\u9752\u6559\u6388\"  \/><\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"V5\" style=\"box-sizing: border-box;\" >\n<section style=\"text-align: center;margin: 10px 0% 20px;box-sizing: border-box;\">\n<section style=\"display: inline-block;width: 97%;vertical-align: top;box-shadow: rgb(140, 140, 140) 0px 0px 3px;box-sizing: border-box;\">\n<section class=\"V5\" style=\"box-sizing: border-box;\" >\n<section style=\"margin: 0.5em auto;box-sizing: border-box;\">\n<section style=\"max-width: 100%;border-radius: 1.5em;display: inline-block;overflow: hidden;box-shadow: rgb(0, 0, 0) 0px 0px 0px;box-sizing: border-box;\"><img     style=\"vertical-align: middle;box-sizing: border-box;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/08\/beepress3-1533788342.jpeg\" alt=\"\u730e\u836f\u4eba\u98ce\u91c7\u4e4b\u590d\u65e6\u7bc7\uff1a\u6768\u9752\u6559\u6388\" title=\"\u730e\u836f\u4eba\u98ce\u91c7\u4e4b\u590d\u65e6\u7bc7\uff1a\u6768\u9752\u6559\u6388\"  \/><\/section>\n<\/section>\n<\/section>\n<section class=\"V5\" style=\"box-sizing: border-box;\" >\n<section style=\"margin: 6px 0%;box-sizing: border-box;\">\n<section style=\"text-align: justify;padding-right: 20px;padding-left: 20px;font-size: 14px;letter-spacing: 0.25px;line-height: 1.8;box-sizing: border-box;\">\n<p style=\"white-space: normal;box-sizing: border-box;\">\u6768\u9752\uff0c\u590d\u65e6\u5927\u5b66\u751f\u547d\u79d1\u5b66\u79d1\u5b66\u9662\u6559\u6388\uff0c\u535a\u58eb\u751f\u5bfc\u5e08\uff0c\u957f\u671f\u4ece\u4e8bIDO\u53ca\u5176\u540c\u5de5\u9176IDO2\u548cTDO\u4e0e\u75be\u75c5\u7684\u5173\u7cfb\u53ca\u5176\u6291\u5236\u5242\u7684\u7814\u53d1\u30022006\u5e74\u4ece\u65e5\u672c\u56de\u56fd\u540e\uff0c\u6768\u9752\u6559\u6388\u5efa\u7acb\u4e86\u56fd\u5185\u9996\u4e2aIDO\u6291\u5236\u5242\u7b5b\u9009\u5e73\u53f0\u548c\u6d3b\u6027\u8bc4\u4ef7\u4f53\u7cfb\u3002\u76f8\u5173\u7814\u7a76\u6210\u679c\u5df2\u7533\u8bf7\u5230\u591a\u4e2a\u56fd\u5185\u4e13\u5229\u548cPCT\u30022016\u5e74\uff0c\u6768\u9752\u6559\u6388\u7684\u79d1\u7814\u6210\u679c\u201cIDO1\u6291\u5236\u5242\u201d\u4ee56500\u4e07\u7f8e\u5143\u91cc\u7a0b\u7891\u4ed8\u6b3e\u7684\u65b9\u5f0f\u6210\u529f\u8f6c\u8ba9\u7ed9\u4e00\u5bb6\u7f8e\u56fd\u516c\u53f8\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"V5\" style=\"box-sizing: border-box;\" >\n<section style=\"margin-right: 0%;margin-bottom: -22px;margin-left: 0%;box-sizing: border-box;\">\n<section style=\"max-width: 100%;vertical-align: middle;display: inline-block;box-shadow: rgb(0, 0, 0) 0px 0px 0px;box-sizing: border-box;\"><img     style=\"vertical-align: middle;box-sizing: border-box;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/08\/beepress3-1533788342.png\" alt=\"\u730e\u836f\u4eba\u98ce\u91c7\u4e4b\u590d\u65e6\u7bc7\uff1a\u6768\u9752\u6559\u6388\" title=\"\u730e\u836f\u4eba\u98ce\u91c7\u4e4b\u590d\u65e6\u7bc7\uff1a\u6768\u9752\u6559\u6388\"  \/><\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"V5\" style=\"box-sizing: border-box;\" >\n<section style=\"box-sizing: border-box;\">\n<section style=\"box-sizing: border-box;\">\n<p style=\"box-sizing: border-box;\"><br style=\"box-sizing: border-box;\"  \/><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"V5\" style=\"box-sizing: border-box;\" >\n<section style=\"margin: 15px 0%;box-sizing: border-box;\">\n<section style=\"display: inline-block;vertical-align: middle;width: 15%;padding-right: 1px;padding-left: 1px;box-sizing: border-box;\">\n<section class=\"V5\" style=\"box-sizing: border-box;\" >\n<section style=\"margin-right: 0%;margin-left: 0%;text-align: center;font-size: 18px;box-sizing: border-box;\">\n<section style=\"display: inline-block;vertical-align: top;border-left: 1px solid rgb(160, 160, 160);border-right: 1px solid rgb(160, 160, 160);padding-right: 5px;padding-left: 5px;color: rgb(161, 116, 82);font-size: 16px;box-sizing: border-box;\">\n<p style=\"display: inline-block;width: 1em;margin-right: 0.2em;margin-left: 0.2em;float: right;clear: none;box-sizing: border-box;\"><strong style=\"box-sizing: border-box;\">\u58f9<\/strong><\/p>\n<p style=\"font-size: 0px;line-height: 0;min-height: 0px;box-sizing: border-box;\"><br style=\"box-sizing: border-box;\"  \/><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"display: inline-block;vertical-align: middle;width: 85%;box-sizing: border-box;\">\n<section class=\"V5\" style=\"box-sizing: border-box;\" >\n<section style=\"box-sizing: border-box;\">\n<section style=\"text-align: justify;color: rgb(62, 62, 62);font-size: 14px;line-height: 1.8;padding-right: 20px;padding-left: 20px;letter-spacing: 0.5px;box-sizing: border-box;\">\n<p style=\"white-space: normal;box-sizing: border-box;\"><strong style=\"box-sizing: border-box;\">IDO\u2014\u2014\u80bf\u7624\u514d\u75ab\u6cbb\u7597\u65b0\u9776\u6807<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"V5\" style=\"box-sizing: border-box;\" >\n<section style=\"margin-top: 0.5em;margin-bottom: 0.5em;box-sizing: border-box;\">\n<section style=\"background-color: rgb(160, 160, 160);height: 1px;box-sizing: border-box;\"><\/section>\n<\/section>\n<\/section>\n<section class=\"V5\" style=\"box-sizing: border-box;\" >\n<section style=\"box-sizing: border-box;\">\n<section style=\"text-align: justify;font-size: 14px;line-height: 1.8;letter-spacing: 0.5px;padding-right: 8px;padding-left: 8px;color: rgb(62, 62, 62);box-sizing: border-box;\">\n<p style=\"white-space: normal;box-sizing: border-box;\"><span style=\"box-sizing: border-box;\">IDO<\/span>\u7684\u5168\u79f0\u662f\u5432\u54da\u80fa-2\uff0c3-\u53cc\u52a0\u6c27\u9176(indoleamine 2\uff0c3-dioxygenase\uff0cIDO)\uff0c\u5b83<span style=\"box-sizing: border-box;\">\u662f\u50ac\u5316\u8272\u6c28\u9178\u6cbf\u72ac\u5c3f\u6c28\u9178\u9014\u5f84\uff08kynurenine pathway, KP\uff09\u5206\u89e3\u7684\u9650\u901f\u9176<\/span>\u3002\u5065\u5eb7\u72b6\u6001\u4e0b\uff0c\u4eba\u4f53\u5185\u7684IDO\u8868\u8fbe\u6c34\u5e73\u8f83\u4f4e\uff0c\u4f46\u5f53\u673a\u4f53\u5904\u4e8e\u611f\u67d3\u3001\u708e\u75c7\u65f6\uff0cIDO\u7684\u8868\u8fbe\u660e\u663e\u589e\u52a0\u3002\u7814\u7a76\u8868\u660e\uff0c\u80bf\u7624\u7ec4\u7ec7\u4e2d\u5b58\u5728\u7740IDO\u8fc7\u8868\u8fbe\u7684\u73b0\u8c61\uff0c\u540c\u65f6\uff0cIDO\u53ef\u8bf1\u5bfc\u80bf\u7624\u8840\u7ba1\u7684\u751f\u6210\u3002\u7531<span style=\"color: rgb(161, 116, 82);\">I<\/span><span style=\"color: rgb(161, 116, 82);box-sizing: border-box;\">DO\u8fc7\u91cf\u8868\u8fbe\u6240\u5bfc\u81f4\u7684\u8272\u6c28\u9178\u4ee3\u8c22\u6c34\u5e73\u5931\u8861<\/span>\u53c2\u4e0e\u4e86\u80bf\u7624\u514d\u75ab\u8010\u53d7\u7684\u5f62\u6210\uff0c\u5176\u8fc7\u5ea6\u8868\u8fbe\u53ef\u901a\u8fc7\u4e00\u7cfb\u5217\u673a\u5236\u963b\u6b62\u6548\u5e94T\u7ec6\u80de\u7684\u751f\u6210\uff0c\u4ece\u800c<span style=\"color: rgb(161, 116, 82);box-sizing: border-box;\">\u4f7f\u80bf\u7624\u9003\u907f\u514d\u75ab\u7cfb\u7edf\u7684\u653b\u51fb<\/span>\u3002<\/p>\n<p style=\"white-space: normal;box-sizing: border-box;\"><br style=\"box-sizing: border-box;\"  \/><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"V5\" style=\"box-sizing: border-box;\" >\n<section style=\"text-align: center;margin: 10px 0%;box-sizing: border-box;\">\n<section style=\"display: inline-block;width: 97%;vertical-align: top;border-top: 5px solid rgb(161, 116, 82);border-top-left-radius: 0px;box-shadow: rgb(160, 160, 160) 0px 1px 2px;padding: 10px;box-sizing: border-box;\">\n<section class=\"V5\" style=\"box-sizing: border-box;\" >\n<section style=\"margin-right: 0%;margin-bottom: 10px;margin-left: 0%;text-align: left;box-sizing: border-box;\">\n<section style=\"display: inline-block;vertical-align: middle;box-sizing: border-box;\">\n<section style=\"max-width: 100%;display: inline-block;vertical-align: bottom;width: 0%;box-shadow: rgb(0, 0, 0) 0px 0px 0px;box-sizing: border-box;\"><img     style=\"vertical-align: middle;width: 100%;box-sizing: border-box;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/08\/beepress5-1533788342.gif\" alt=\"\u730e\u836f\u4eba\u98ce\u91c7\u4e4b\u590d\u65e6\u7bc7\uff1a\u6768\u9752\u6559\u6388\" title=\"\u730e\u836f\u4eba\u98ce\u91c7\u4e4b\u590d\u65e6\u7bc7\uff1a\u6768\u9752\u6559\u6388\"  \/><\/section>\n<section style=\"display: inline-block;vertical-align: bottom;padding-left: 5px;padding-right: 5px;line-height: 1.2em;margin-bottom: 2px;font-size: 12px;box-sizing: border-box;\">\n<p style=\"box-sizing: border-box;\">\u25bcIDO\u50ac\u5316\u8272\u6c28\u9178\u964d\u89e3\u4e3a\u72ac\u5c3f\u6c28\u9178<\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"V5\" style=\"box-sizing: border-box;\" >\n<section style=\"margin-top: 10px;margin-right: 0%;margin-left: 0%;box-sizing: border-box;\">\n<section style=\"max-width: 100%;vertical-align: middle;display: inline-block;box-sizing: border-box;\"><img     style=\"vertical-align: middle;box-sizing: border-box;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/08\/beepress3-1533788342.gif\" alt=\"\u730e\u836f\u4eba\u98ce\u91c7\u4e4b\u590d\u65e6\u7bc7\uff1a\u6768\u9752\u6559\u6388\" title=\"\u730e\u836f\u4eba\u98ce\u91c7\u4e4b\u590d\u65e6\u7bc7\uff1a\u6768\u9752\u6559\u6388\"  \/><\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"V5\" style=\"box-sizing: border-box;\" >\n<section style=\"box-sizing: border-box;\">\n<section style=\"box-sizing: border-box;\">\n<p style=\"box-sizing: border-box;\"><br style=\"box-sizing: border-box;\"  \/><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"V5\" style=\"box-sizing: border-box;\" >\n<section style=\"box-sizing: border-box;\">\n<section style=\"text-align: justify;font-size: 14px;line-height: 1.8;letter-spacing: 0.25px;padding-right: 8px;padding-left: 8px;box-sizing: border-box;\">\n<p style=\"white-space: normal;box-sizing: border-box;\">IDO\u5728\u6297\u539f\u63d0\u5448\u7ec6\u80de\u7684\u9ad8\u8868\u8fbe\u4f7f\u5f97\u8272\u6c28\u9178\u8017\u7aed\uff0c\u5bfc\u81f4T\u7ec6\u80de\u505c\u6ede\u4e8eG1\u671f\uff0c\u8fdb\u800c\u589e\u6b96\u53d7\u5230\u6291\u5236\u3002\u53e6\u4e00\u65b9\u9762\uff0c\u8272\u6c28\u9178\u964d\u89e3\u5f15\u8d77\u72ac\u5c3f\u6c28\u9178\u79ef\u7d2f\uff0c\u80fd\u591f<span style=\"color: rgb(161, 116, 82);box-sizing: border-box;\">\u8bf1\u5bfc\u6548\u5e94T\u7ec6\u80de\u7684\u51cb\u4ea1\uff0c\u8fdb\u800c\u6291\u5236\u5176\u5bf9\u80bf\u7624\u7ec6\u80de\u7684\u653b\u51fb<\/span>\uff1b\u4e5f\u80fd<span style=\"color: rgb(161, 116, 82);box-sizing: border-box;\">\u52a0\u5f3a\u5c40\u90e8\u8c03\u8282\u6027T\u7ec6\u80de\uff08Treg\uff09\u4ecb\u5bfc\u7684\u514d\u75ab\u6291\u5236\uff0c\u4fc3\u4f7f\u673a\u4f53\u5bf9\u80bf\u7624\u7279\u5f02\u6027\u6297\u539f\u7684\u5916\u5468\u514d\u75ab\u8010\u53d7<\/span>\u3002<br style=\"box-sizing: border-box;\"  \/><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"V5\" style=\"box-sizing: border-box;\" >\n<section style=\"box-sizing: border-box;\">\n<section style=\"box-sizing: border-box;\">\n<p style=\"box-sizing: border-box;\"><br style=\"box-sizing: border-box;\"  \/><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"V5\" style=\"box-sizing: border-box;\" >\n<section style=\"text-align: center;margin: 10px 0%;box-sizing: border-box;\">\n<section style=\"display: inline-block;width: 97%;vertical-align: top;border-top: 5px solid rgb(161, 116, 82);border-top-left-radius: 0px;box-shadow: rgb(160, 160, 160) 0px 1px 2px;padding: 10px;box-sizing: border-box;\">\n<section class=\"V5\" style=\"box-sizing: border-box;\" >\n<section style=\"margin-right: 0%;margin-bottom: 10px;margin-left: 0%;text-align: left;box-sizing: border-box;\">\n<section style=\"display: inline-block;vertical-align: middle;box-sizing: border-box;\">\n<section style=\"max-width: 100%;display: inline-block;vertical-align: bottom;width: 0%;box-shadow: rgb(0, 0, 0) 0px 0px 0px;box-sizing: border-box;\"><img     style=\"vertical-align: middle;width: 100%;box-sizing: border-box;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/08\/beepress2-1533788343.gif\" alt=\"\u730e\u836f\u4eba\u98ce\u91c7\u4e4b\u590d\u65e6\u7bc7\uff1a\u6768\u9752\u6559\u6388\" title=\"\u730e\u836f\u4eba\u98ce\u91c7\u4e4b\u590d\u65e6\u7bc7\uff1a\u6768\u9752\u6559\u6388\"  \/><\/section>\n<section style=\"display: inline-block;vertical-align: bottom;padding-left: 5px;padding-right: 5px;line-height: 1.2em;margin-bottom: 2px;font-size: 12px;box-sizing: border-box;\">\n<p style=\"box-sizing: border-box;\">\u25bc IDO\u5f15\u8d77\u80bf\u7624\u7ec6\u80de\u514d\u75ab\u8010\u53d7\u7684\u673a\u5236<\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"V5\" style=\"box-sizing: border-box;\" >\n<section style=\"margin-top: 10px;margin-right: 0%;margin-left: 0%;box-sizing: border-box;\">\n<section style=\"max-width: 100%;vertical-align: middle;display: inline-block;box-shadow: rgb(0, 0, 0) 0px 0px 0px;box-sizing: border-box;\"><img     style=\"vertical-align: middle;box-sizing: border-box;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/08\/beepress0-1533788343.jpg\" alt=\"\u730e\u836f\u4eba\u98ce\u91c7\u4e4b\u590d\u65e6\u7bc7\uff1a\u6768\u9752\u6559\u6388\" title=\"\u730e\u836f\u4eba\u98ce\u91c7\u4e4b\u590d\u65e6\u7bc7\uff1a\u6768\u9752\u6559\u6388\"  \/><\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"V5\" style=\"box-sizing: border-box;\" >\n<section style=\"box-sizing: border-box;\">\n<section style=\"box-sizing: border-box;\">\n<p style=\"box-sizing: border-box;\"><br style=\"box-sizing: border-box;\"  \/><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"V5\" style=\"box-sizing: border-box;\" >\n<section style=\"box-sizing: border-box;\">\n<section style=\"font-size: 14px;line-height: 1.8;letter-spacing: 0.25px;padding-right: 8px;padding-left: 8px;box-sizing: border-box;\">\n<p style=\"box-sizing: border-box;\">IDO\u6709\u4e24\u4e2a\u540c\u5de5\u9176TDO\u548cIDO2\u3002TDO\u5728\u591a\u79cd\u80bf\u7624\u7684\u514d\u75ab\u9003\u9038\u4e2d\u8d77\u4e00\u5b9a\u4f5c\u7528\uff0c\u800cIDO2\u5728T\u7ec6\u80de\u5bf9\u80bf\u7624\u6297\u539f\u7684\u514d\u75ab\u8010\u53d7\u4e2d\u7684\u89d2\u8272\u548c\u673a\u5236\u8fd8\u6709\u5f85\u6df1\u5165\u7814\u7a76\u3002\u76ee\u524d\uff0c\u5df2\u6709\u7684IDO\u6291\u5236\u5242\u5305\u62ec\u7ade\u4e89\u6027\u6291\u5236\u5242\uff08\u8272\u6c28\u9178\u884d\u751f\u7269\uff09\u3001\u975e\u7ade\u4e89\u6291\u5236\u5242\uff08\u82ef\u57fa\u54aa\u5511\uff09\u3001\u53cd\u7ade\u4e89\u6291\u5236\u5242\uff08\u751f\u7269\u78b1exiguamine\uff09\u7b49\u7c7b\u578b\u3002<br style=\"box-sizing: border-box;\"  \/><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"V5\" style=\"box-sizing: border-box;\" >\n<section style=\"box-sizing: border-box;\">\n<section style=\"box-sizing: border-box;\">\n<p style=\"box-sizing: border-box;\"><br style=\"box-sizing: border-box;\"  \/><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"V5\" style=\"box-sizing: border-box;\" >\n<section style=\"box-sizing: border-box;\">\n<section style=\"text-align: justify;font-size: 14px;line-height: 1.8;letter-spacing: 0.5px;padding-right: 8px;padding-left: 8px;box-sizing: border-box;\">\n<p style=\"white-space: normal;box-sizing: border-box;\">IDO\u65e9\u5148\u88ab\u8bc1\u5b9e\u4e0e\u963f\u5c14\u5179\u6d77\u9ed8\u75c7\u3001\u8001\u5e74\u6027\u767d\u5185\u969c\u3001\u6291\u90c1\u75c7\u7b49\u91cd\u5927\u75be\u75c5\u6709\u7740\u5bc6\u5207\u7684\u5173\u7cfb\u3002\u540e\u6765\u4f34\u968f\u80bf\u7624\u514d\u75ab\u6cbb\u7597\u6d6a\u6f6e\u7684\u5174\u8d77\uff0c<span style=\"color: rgb(161, 116, 82);box-sizing: border-box;\">IDO\u4f5c\u4e3a\u80bf\u7624\u514d\u75ab\u6cbb\u7597\u7684\u65b0\u9776\u70b9\u5f00\u59cb\u5d2d\u9732\u5934\u89d2<\/span>\u3002\u968f\u7740\u7f57\u6c0f\u5236\u836f\u516c\u53f8\u3001\u9ed8\u6c99\u4e1c\u3001\u767e\u65f6\u7f8e\u65bd\u8d35\u5b9d\uff08BMS\uff09\u7b49\u5236\u836f\u5de8\u5934\u7eb7\u7eb7\u9009\u62e9\u4e0eIncyte\u3001NewLink\u7b49\u516c\u53f8\u7814\u53d1\u7684IDO\u6291\u5236\u5242\u5c55\u5f00\u5408\u4f5c\uff0c\u5bf9IDO\u6291\u5236\u5242\u8fd9\u4e00\u9886\u57df\u7684\u5173\u6ce8\u8fc5\u901f\u63d0\u5347\uff0c\u5168\u7403\u8fdb\u5165\u4e86\u7b2c\u4e00\u6ce2\u7814\u53d1\u9ad8\u6f6e\u3002\u7136\u800c<span style=\"color: rgb(62, 62, 62);box-sizing: border-box;\">\uff0c\u5230\u76ee\u524d\u4e3a\u6b62\uff0c\u4e16\u754c\u4e0a\u8fd8\u6ca1\u6709IDO\u6291\u5236\u5242\u8fdb\u5165\u5e02\u573a\u3002<\/span>\u73b0\u9636\u6bb5\u8868\u73b0\u6700\u62a2\u773c\u7684\u662f<span style=\"color: rgb(161, 116, 82);box-sizing: border-box;\">Incyte\u516c\u53f8\u7684Epacadostat(INCB024360)<\/span>\u548c<span style=\"color: rgb(161, 116, 82);box-sizing: border-box;\">Newlink\u516c\u53f8\u7684indoximod\u548cGDC-0919(NLG-919)<\/span>\uff0c\u8fd9\u4e9b\u836f\u7269<span style=\"color: rgb(161, 116, 82);box-sizing: border-box;\">\u76ee\u524d\u5747\u5df2\u8fdb\u5165\u4e34\u5e8a\u5b9e\u9a8c<\/span><span style=\"color: rgb(161, 116, 82);box-sizing: border-box;\">\u3002<\/span><\/p>\n<p style=\"white-space: normal;box-sizing: border-box;\"><br style=\"box-sizing: border-box;\"  \/><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"V5\" style=\"box-sizing: border-box;\" >\n<section style=\"box-sizing: border-box;\">\n<section style=\"box-sizing: border-box;\">\n<p style=\"box-sizing: border-box;\"><br style=\"box-sizing: border-box;\"  \/><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"V5\" style=\"box-sizing: border-box;\" >\n<section style=\"margin: 15px 0%;box-sizing: border-box;\">\n<section style=\"display: inline-block;vertical-align: middle;width: 15%;padding-right: 1px;padding-left: 1px;box-sizing: border-box;\">\n<section class=\"V5\" style=\"box-sizing: border-box;\" >\n<section style=\"margin-right: 0%;margin-left: 0%;text-align: center;font-size: 18px;box-sizing: border-box;\">\n<section style=\"display: inline-block;vertical-align: top;border-left: 1px solid rgb(160, 160, 160);border-right: 1px solid rgb(160, 160, 160);padding-right: 5px;padding-left: 5px;color: rgb(94, 122, 71);font-size: 16px;box-sizing: border-box;\">\n<p style=\"display: inline-block;width: 1em;margin-right: 0.2em;margin-left: 0.2em;float: right;clear: none;box-sizing: border-box;\"><strong style=\"box-sizing: border-box;\">\u8d30<\/strong><\/p>\n<p style=\"font-size: 0px;line-height: 0;min-height: 0px;box-sizing: border-box;\"><br style=\"box-sizing: border-box;\"  \/><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"display: inline-block;vertical-align: middle;width: 85%;box-sizing: border-box;\">\n<section class=\"V5\" style=\"box-sizing: border-box;\" >\n<section style=\"box-sizing: border-box;\">\n<section style=\"text-align: justify;color: rgb(62, 62, 62);font-size: 14px;line-height: 1.8;padding-right: 20px;padding-left: 20px;letter-spacing: 0.5px;box-sizing: border-box;\">\n<p style=\"white-space: normal;box-sizing: border-box;\"><strong style=\"box-sizing: border-box;\">\u5386\u7ecf\u79cd\u79cd\u78e8\u96be\uff0c\u7855\u679c\u6210\u529f\u8f6c\u5316<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"V5\" style=\"box-sizing: border-box;\" >\n<section style=\"margin-top: 0.5em;margin-bottom: 0.5em;box-sizing: border-box;\">\n<section style=\"background-color: rgb(160, 160, 160);height: 1px;box-sizing: border-box;\"><\/section>\n<\/section>\n<\/section>\n<section class=\"V5\" style=\"box-sizing: border-box;\" >\n<section style=\"box-sizing: border-box;\">\n<section style=\"text-align: justify;font-size: 14px;line-height: 1.8;letter-spacing: 0.25px;padding-right: 8px;padding-left: 8px;box-sizing: border-box;\">\n<p style=\"white-space: normal;box-sizing: border-box;\"><span style=\"color: rgb(94, 122, 71);box-sizing: border-box;\">2016\u5e743\u670825\u65e5\uff0c\u590d\u65e6\u5927\u5b66\u5c06\u5177\u6709\u81ea\u4e3b\u77e5\u8bc6\u4ea7\u6743\u7684\u201cIDO\u6291\u5236\u5242\u201d\u6210\u529f\u8f6c\u5316\u7ed9\u4e00\u5bb6\u7f8e\u56fd\u516c\u53f8\u3002<span style=\"color: rgb(62, 62, 62);box-sizing: border-box;\">\u8be5\u516c\u53f8<\/span><\/span>\u5c06\u4ee5\u91cc\u7a0b\u7891\u7684\u4ed8\u6b3e\u6a21\u5f0f\u8fdb\u884c\u652f\u4ed8\u3002\u53cc\u65b9\u8fbe\u6210\u534f\u8bae\uff0c\u8be5\u516c\u53f8\u5c06\u5411\u590d\u65e6\u5927\u5b66\u652f\u4ed8\u4e00\u5b9a\u989d\u5ea6\u7684\u9996\u4ed8\u6b3e\uff0c\u4ee5\u83b7\u5f97\u8be5\u836f\u7269\u9664\u4e2d\u56fd\u5927\u9646\u3001\u6e2f\u6fb3\u53f0\u5730\u533a\u4ee5\u5916\u7684\u5168\u7403\u72ec\u5bb6\u4e34\u5e8a\u5f00\u53d1\u548c\u5e02\u573a\u9500\u552e\u7684\u6743\u5229\u3002\u82e5\u8be5IDO\u6291\u5236\u5242\u5728\u56fd\u5916\u4e34\u5e8a\u8bd5\u9a8c\u7ed3\u679c\u53d6\u5f97\u4f18\u826f\u6548\u679c\uff0c\u5728\u6b27\u76df\u3001\u7f8e\u56fd\u3001\u65e5\u672c\u6210\u529f\u4e0a\u5e02\uff0c\u5e74\u9500\u552e\u989d\u8fbe\u5230\u4e0d\u540c\u7684\u76ee\u6807\u540e\uff0c\u8be5\u516c\u53f8\u5411\u590d\u65e6\u5927\u5b66\u652f\u4ed8\u7d2f\u8ba1\u4e0d\u8d85\u8fc76500\u4e07\u7f8e\u5143\u7684\u6b3e\u9879\u3002<\/p>\n<p style=\"white-space: normal;box-sizing: border-box;\"><br style=\"box-sizing: border-box;\"  \/><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"V5\" style=\"box-sizing: border-box;\" >\n<section style=\"text-align: center;margin: 10px 0%;box-sizing: border-box;\">\n<section style=\"display: inline-block;width: 97%;vertical-align: top;border-top: 5px solid rgb(94, 122, 71);border-top-left-radius: 0px;box-shadow: rgb(160, 160, 160) 0px 1px 2px;padding: 10px;box-sizing: border-box;\">\n<section class=\"V5\" style=\"box-sizing: border-box;\" >\n<section style=\"margin-right: 0%;margin-bottom: 10px;margin-left: 0%;text-align: left;box-sizing: border-box;\">\n<section style=\"display: inline-block;vertical-align: middle;box-sizing: border-box;\">\n<section style=\"max-width: 100%;display: inline-block;vertical-align: bottom;width: 0%;box-shadow: rgb(0, 0, 0) 0px 0px 0px;box-sizing: border-box;\"><img     style=\"vertical-align: middle;width: 100%;box-sizing: border-box;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/08\/beepress9-1533788343.gif\" alt=\"\u730e\u836f\u4eba\u98ce\u91c7\u4e4b\u590d\u65e6\u7bc7\uff1a\u6768\u9752\u6559\u6388\" title=\"\u730e\u836f\u4eba\u98ce\u91c7\u4e4b\u590d\u65e6\u7bc7\uff1a\u6768\u9752\u6559\u6388\"  \/><\/section>\n<section style=\"display: inline-block;vertical-align: bottom;padding-left: 5px;padding-right: 5px;line-height: 1.2em;margin-bottom: 2px;font-size: 12px;box-sizing: border-box;\">\n<p style=\"box-sizing: border-box;\">\u25bc\u6768\u9752\u6559\u6388\u7684\u79d1\u7814\u6210\u679c\u201cIDO\u6291\u5236\u5242\u201d\u6210\u529f\u8f6c\u5316<\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"V5\" style=\"box-sizing: border-box;\" >\n<section style=\"margin-top: 10px;margin-right: 0%;margin-left: 0%;box-sizing: border-box;\">\n<section style=\"max-width: 100%;vertical-align: middle;display: inline-block;box-shadow: rgb(0, 0, 0) 0px 0px 0px;box-sizing: border-box;\"><img     style=\"vertical-align: middle;box-sizing: border-box;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/08\/beepress7-1533788343.jpeg\" alt=\"\u730e\u836f\u4eba\u98ce\u91c7\u4e4b\u590d\u65e6\u7bc7\uff1a\u6768\u9752\u6559\u6388\" title=\"\u730e\u836f\u4eba\u98ce\u91c7\u4e4b\u590d\u65e6\u7bc7\uff1a\u6768\u9752\u6559\u6388\"  \/><\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"V5\" style=\"box-sizing: border-box;\" >\n<section style=\"box-sizing: border-box;\">\n<section style=\"text-align: justify;font-size: 14px;line-height: 1.8;letter-spacing: 0.25px;padding-right: 8px;padding-left: 8px;box-sizing: border-box;\">\n<p style=\"white-space: normal;box-sizing: border-box;\"><br style=\"box-sizing: border-box;\"  \/><\/p>\n<p style=\"white-space: normal;box-sizing: border-box;\">\u4f5c\u4e3a\u56fd\u5185IDO\u6291\u5236\u5242\u7814\u53d1\u9886\u57df\u7684\u62d3\u8352\u8005\uff0c\u56de\u56fd\u521d\u671f\uff0c\u6768\u9752\u8bfe\u9898\u7ec4\u9762\u4e34\u7740\u8d44\u91d1\u77ed\u7f3a\uff0c\u627e\u4e0d\u5230\u5408\u4f5c\u8005\u7b49\u8bf8\u591a\u96be\u9898\u3002\u5341\u51e0\u5e74\u7684\u7814\u53d1\u8fc7\u7a0b\u4e2d\uff0c\u6768\u9752\u6559\u6388\u5e26\u9886\u56e2\u961f\u4e0d\u65ad\u5730\u514b\u670d\u4e86\u8bf8\u591a\u56f0\u96be\uff0c\u8fdb\u884c\u4e86\u5927\u91cf\u7684\u57fa\u7840\u7814\u7a76\u548c\u524d\u671f\u5de5\u4f5c\u30022015\u5e74\uff0c\u6768\u9752\u6559\u6388\u7684\u79d1\u7814\u6210\u679c\u5df2\u7533\u8bf7\u5e76\u83b7\u5f97\u591a\u9879\u4e13\u5229\uff0c\u5e76\u53d7\u5230\u56fd\u5185\u5916\u591a\u5bb6\u5236\u836f\u4f01\u4e1a\u7684\u9752\u7750\u3002<span style=\"color: rgb(94, 122, 71);box-sizing: border-box;\">\u6b64\u6b21\u6210\u529f\u8f6c\u5316\u7684IDO\u6291\u5236\u5242\u662f\u6211\u56fd\u5728\u8be5\u9886\u57df\u4e2d\u9996\u4e2a\u6210\u529f\u8f6c\u5316\u9879\u76ee\uff0c\u5ba2\u89c2\u4e0a\u8bf4\u660e\u4e86\u6211\u56fd\u9ad8\u6821\u79d1\u7814\u5b9e\u529b\u7684\u63d0\u5347\uff0c\u540c\u65f6\uff0c\u4e5f\u4e3a\u9ad8\u6821\u57fa\u7840\u7814\u7a76\u6210\u679c\u8f6c\u5316\u63d0\u4f9b\u4e86\u793a\u8303\u548c\u7ecf\u9a8c\u3002<\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"V5\" style=\"box-sizing: border-box;\" >\n<section style=\"box-sizing: border-box;\">\n<section style=\"box-sizing: border-box;\">\n<p style=\"box-sizing: border-box;\"><br style=\"box-sizing: border-box;\"  \/><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"V5\" style=\"box-sizing: border-box;\" >\n<section style=\"margin: 15px 0%;box-sizing: border-box;\">\n<section style=\"display: inline-block;vertical-align: middle;width: 15%;padding-right: 1px;padding-left: 1px;box-sizing: border-box;\">\n<section class=\"V5\" style=\"box-sizing: border-box;\" >\n<section style=\"margin-right: 0%;margin-left: 0%;text-align: center;font-size: 18px;box-sizing: border-box;\">\n<section style=\"display: inline-block;vertical-align: top;border-left: 1px solid rgb(160, 160, 160);border-right: 1px solid rgb(160, 160, 160);padding-right: 5px;padding-left: 5px;color: rgb(162, 48, 38);font-size: 16px;box-sizing: border-box;\">\n<p style=\"display: inline-block;width: 1em;margin-right: 0.2em;margin-left: 0.2em;float: right;clear: none;box-sizing: border-box;\"><strong style=\"box-sizing: border-box;\">\u53c1<\/strong><\/p>\n<p style=\"font-size: 0px;line-height: 0;min-height: 0px;box-sizing: border-box;\"><br style=\"box-sizing: border-box;\"  \/><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"display: inline-block;vertical-align: middle;width: 85%;box-sizing: border-box;\">\n<section class=\"V5\" style=\"box-sizing: border-box;\" >\n<section style=\"box-sizing: border-box;\">\n<section style=\"text-align: justify;color: rgb(62, 62, 62);font-size: 14px;line-height: 1.8;padding-right: 20px;padding-left: 20px;letter-spacing: 0.5px;box-sizing: border-box;\">\n<p style=\"white-space: normal;box-sizing: border-box;\"><strong style=\"box-sizing: border-box;\">\u7acb\u8db3\u57fa\u7840\u7814\u7a76\uff0c\u628a\u63e1\u524d\u6cbf\u52a8\u6001<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"V5\" style=\"box-sizing: border-box;\" >\n<section style=\"margin-top: 0.5em;margin-bottom: 0.5em;box-sizing: border-box;\">\n<section style=\"background-color: rgb(160, 160, 160);height: 1px;box-sizing: border-box;\"><\/section>\n<\/section>\n<\/section>\n<section class=\"V5\" style=\"box-sizing: border-box;\" >\n<section style=\"box-sizing: border-box;\">\n<section style=\"text-align: justify;font-size: 14px;line-height: 1.8;letter-spacing: 0.25px;padding-right: 8px;padding-left: 8px;box-sizing: border-box;\">\n<p style=\"white-space: normal;box-sizing: border-box;\">\u57fa\u7840\u7814\u7a76\u5bf9\u4e8e\u836f\u7269\u7684\u6e90\u5934\u521b\u65b0\u81f3\u5173\u91cd\u8981\u3002\u56de\u56fd\u540e\uff0c\u6768\u9752\u6559\u6388\u4e00\u76f4\u5e26\u9886\u56e2\u961f\u63a2\u7a76IDO\u4e0eIDO\u6291\u5236\u5242\u5728\u5404\u79cd\u91cd\u5927\u75be\u75c5\u7684\u4f5c\u7528\u3002\u521a\u56de\u56fd\u65f6\uff0c\u6768\u9752\u6559\u6388\u53d1\u73b0\u7531\u4e8e\u7f3a\u4e4f\u5546\u54c1\u5316\u7684IDO\uff0c\u56fd\u5185\u65e0\u6cd5\u5f00\u5c55IDO\u6291\u5236\u5242\u7684\u7b5b\u9009\u5de5\u4f5c\u3002\u4e8e\u662f\u6768\u9752\u6559\u6388\u5e26\u9886\u56e2\u961f\u5f00\u5c55\u76f8\u5173\u5b9e\u9a8c\u5e76\u83b7\u5f97\u4e86\u91cd\u7ec4\u4eba\u6e90IDO\uff0c\u5efa\u7acb\u4e86\u9176\u6d3b\u6027\u6821\u6d4b\u7cfb\u7edf\u548cIDO1\u7684\u7b5b\u9009\u5e73\u53f0\u3002<span style=\"color: rgb(162, 48, 38);box-sizing: border-box;\">\u7ecf\u8fc7\u591a\u5e74\u7684\u7814\u7a76\uff0c\u6768\u9752\u6559\u6388\u8bfe\u9898\u7ec4\u53d6\u5f97\u4e86\u8bf8\u591a\u6210\u679c\uff1a<\/span>\u4ece\u5929\u7136\u4ea7\u7269\u4e2d\u53d1\u73b0\u591a\u79cd\u5177\u6709\u826f\u597d\u6d3b\u6027\u7684IDO\u6291\u5236\u5242\uff08<span style=\"color: rgb(162, 48, 38);box-sizing: border-box;\"><em style=\"box-sizing: border-box;\">J Med Chem<\/em>,&nbsp;<strong style=\"box-sizing: border-box;\">2013<\/strong>,&nbsp;56\uff1a8321\u20138331<\/span>\uff09\uff1b\u53d1\u73b0\u591a\u4e2a\u5177\u6709\u9ad8\u6548\u7684\u6d3b\u6027\u57fa\u56e2\u548c\u5206\u5b50\uff1b\u901a\u8fc7\u5b9e\u9a8c\u63d0\u51fa\u4e86\u9ec4\u8fde\u89e3\u6bd2\u6c64\u6cbb\u7597\u963f\u5c14\u5179\u6d77\u9ed8\u7684\u5206\u5b50\u673a\u5236\u53ef\u80fd\u662f\u4e0b\u8c03IDO\u6d3b\u6027\u8fd9\u4e00\u5177\u6709\u521b\u65b0\u6027\u7684\u89c2\u70b9\uff08<span style=\"color: rgb(162, 48, 38);box-sizing: border-box;\"><em style=\"box-sizing: border-box;\">J Alzheimers Dis <\/em>,&nbsp;<strong style=\"box-sizing: border-box;\">2010<\/strong>&nbsp;,&nbsp;22:257<\/span>\uff09\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"V5\" style=\"box-sizing: border-box;\" >\n<section style=\"box-sizing: border-box;\">\n<section style=\"text-align: justify;font-size: 14px;line-height: 1.8;letter-spacing: 0.25px;padding-right: 8px;padding-left: 8px;box-sizing: border-box;\">\n<p style=\"white-space: normal;box-sizing: border-box;\"><br style=\"box-sizing: border-box;\"  \/><\/p>\n<p style=\"white-space: normal;box-sizing: border-box;\"><span style=\"color: rgb(162, 48, 38);box-sizing: border-box;\">\u76ee\u524d\uff0c\u6768\u9752\u6559\u6388\u8bfe\u9898\u7ec4\u56f4\u7ed5IDO\u6291\u5236\u5242\u9886\u57df\u7684\u4e00\u4e9b\u524d\u6cbf\u95ee\u9898\u5c55\u5f00\u7814\u7a76<\/span><span style=\"color: rgb(162, 48, 38);box-sizing: border-box;\">\uff0c<\/span>\u5305\u62ecIDO\/TDO\u4e0e\u795e\u7ecf\u7cfb\u7edf\u75be\u75c5\u3001\u764c\u75c7\u4ee5\u53ca\u5fc3\u8111\u8840\u7ba1\u75be\u75c5\u7b49\u75be\u75c5\u53d1\u75c5\u7684\u5173\u7cfb\uff1b\u5229\u7528\u751f\u7269\u4fe1\u606f\u5b66\u7684\u624b\u6bb5\u5bfb\u627ebiomarker\u4ece\u800c\u627e\u5230\u9002\u5408\u836f\u7269\u6cbb\u7597\u7684\u60a3\u8005\uff1b \u7528\u5df2\u9a8c\u8bc1\u8fc7\u7684IDO\u6291\u5236\u5242\u4f5c\u4e3a\u63a2\u9488\uff0c\u53bb\u53d1\u73b0IDO\u548c\u80bf\u7624\u514d\u75ab\u8c03\u8282\u7684\u5173\u7cfb \uff0c\u540c\u65f6\u8bfe\u9898\u7ec4\u4e5f\u5728\u52aa\u529b\u5f00\u53d1IDO\u6291\u5236\u5242\u548cIDO\u7684\u7ed3\u6676\u3002<\/p>\n<p style=\"white-space: normal;box-sizing: border-box;\"><br style=\"box-sizing: border-box;\"  \/><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"V5\" style=\"box-sizing: border-box;\" >\n<section style=\"box-sizing: border-box;\">\n<section style=\"text-align: justify;font-size: 14px;line-height: 1.8;letter-spacing: 0.25px;padding-right: 8px;padding-left: 8px;box-sizing: border-box;\">\n<p style=\"white-space: normal;box-sizing: border-box;\">IDO\u6291\u5236\u5242\u4f5c\u4e3a\u80bf\u7624\u514d\u75ab\u6cbb\u7597\u7684\u65b0\u6210\u5458\uff0c\u5176\u7814\u53d1\u4e4b\u8def\u4e0a\u4f9d\u7136\u9762\u4e34\u7740\u8bf8\u591a\u6311\u6218\u3002\u9ed8\u6c99\u4e1c(MSD)\u5728\u4eca\u5e744\u6708\u4efd\u5ba3\u5e03,\u6d3e\u59c6\u5355\u6297(Keytruda)\u8054\u5408Incyte\u516c\u53f8IDO\u6291\u5236\u5242\u6cbb\u7597\u9ed1\u8272\u7d20\u7624\u7684\u2162\u671f\u4e34\u5e8a\u7814\u7a76\u5931\u8d25\u3002\u968f\u540e\uff0c\u591a\u5bb6\u5236\u836f\u5de8\u5934\u5ba3\u5e03\u505c\u6b62IDO\u6291\u5236\u5242\u7684\u4e34\u5e8a\u5b9e\u9a8c\u3002\u6768\u9752\u6559\u6388\u8ba4\u4e3a\u5728\u65b0\u836f\u7814\u53d1\u8fc7\u7a0b\u4e2d\uff0c\u51fa\u73b0\u95ee\u9898\u662f\u6b63\u5e38\u7684\u4e8b\u60c5\u3002\u8fd9\u4e9b\u4e34\u5e8a\u7814\u7a76\u7684\u5931\u8d25\u66b4\u9732\u51fa\u8fd9\u4e2a\u9886\u57df\u76ee\u524d\u6240\u5b58\u5728\u7684\u4e00\u4e9b\u95ee\u9898\u3002<span style=\"color: rgb(162, 48, 38);box-sizing: 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style=\"box-sizing: border-box;\" >\n<section style=\"box-sizing: border-box;\">\n<section style=\"text-align: justify;font-size: 14px;line-height: 1.8;letter-spacing: 0.25px;padding-right: 4px;padding-left: 4px;box-sizing: border-box;\">\n<p style=\"white-space: normal;box-sizing: 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center;margin-top: -10px;margin-right: 0%;margin-left: 0%;box-sizing: border-box;\">\n<section style=\"max-width: 100%;vertical-align: middle;display: inline-block;box-sizing: border-box;\"><svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" x=\"0px\" y=\"0px\" viewbox=\"0 0 536.1 59.2\" style=\"vertical-align: middle;max-width: 100%;box-sizing: border-box;\" width=\"536.1\"><g style=\"box-sizing: border-box;\"><polygon points=\"533.5,3 518.7,19.1 503.1,1 486.9,18.6 471.3,0.5 455.1,18.1 439.5,0 422,19.1 424.6,21.5 439.4,5.3 455,23.4    471.2,5.8 486.8,23.9 503,6.3 518.6,24.4 536.1,5.4\" fill=\"#000000\" style=\"box-sizing: border-box;\"><\/polygon><g style=\"box-sizing: border-box;\"><polygon points=\"89.5,28.7 82.5,39.3 96.5,39.3\" fill=\"#000000\" style=\"box-sizing: border-box;\"><\/polygon><polygon points=\"68.9,28.7 61.9,39.3 75.9,39.3\" fill=\"#000000\" style=\"box-sizing: border-box;\"><\/polygon><polygon points=\"48.2,28.7 41.3,39.3 55.2,39.3\" fill=\"#000000\" style=\"box-sizing: 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class=\"V5\" style=\"box-sizing: border-box;\" >\n<section style=\"margin: 10px;box-sizing: border-box;\">\n<section style=\"display: inline-block;width: 100%;vertical-align: top;padding-right: 10px;padding-left: 10px;border-style: dashed;border-width: 1px;border-radius: 0px;border-color: rgb(62, 62, 62);box-sizing: border-box;\">\n<section class=\"V5\" style=\"box-sizing: border-box;\" >\n<section style=\"margin: 10px 0%;box-sizing: border-box;\">\n<section style=\"display: inline-block;width: 100%;border-width: 0px 0px 0px 10px;border-style: solid;border-left-color: rgb(144, 215, 236);border-right-color: rgb(162, 48, 38);box-shadow: rgb(0, 0, 0) 0px 0px 0px;border-bottom-left-radius: 0px;box-sizing: border-box;\">\n<section class=\"V5\" style=\"box-sizing: border-box;\" >\n<section style=\"margin-right: 0%;margin-left: 0%;padding-right: 3px;padding-left: 3px;box-sizing: border-box;\">\n<section style=\"display: inline-block;width: 100%;vertical-align: top;margin-bottom: -0.65em;margin-top: 0.95em;box-sizing: border-box;\">\n<section style=\"width: 100%;box-sizing: border-box;\">\n<section style=\"border-top: 1px solid rgb(0, 0, 0);width: 99.9%;float: left;box-sizing: border-box;\"><\/section>\n<section style=\"width: 6px;height: 6px;margin-top: -3px;border-radius: 100%;float: right;background-color: rgb(162, 48, 38);box-sizing: border-box;\"><\/section>\n<\/section>\n<section style=\"display: inline-block;margin-top: -1em;vertical-align: top;background-color: rgb(255, 255, 255);padding: 3px 10px;color: rgb(162, 48, 38);box-sizing: border-box;\">\n<p style=\"box-sizing: border-box;\"><strong style=\"box-sizing: border-box;\">\u5f80\u671f\u56de\u987e<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"V5\" style=\"box-sizing: border-box;\" ><a title=\"https:\/\/mp.weixin.qq.com\/s?__biz=MzAwMTEwNTc4OA==&amp;mid=2653513142&amp;idx=1&amp;sn=ad5410cfe6ebd55980aed0af2bf3bfa6&amp;chksm=81030fa5b67486b3743d4fbbf0f1a70476b8edc21439a1c2c01642e56a27aeba7418ef392199&amp;scene=21#wechat_redirect\" formlinkparm=\"&quot;https:\/\/mp.weixin.qq.com\/s?__biz=MzAwMTEwNTc4OA==&amp;mid=2653513142&amp;idx=1&amp;sn=ad5410cfe6ebd55980aed0af2bf3bfa6&amp;chksm=81030fa5b67486b3743d4fbbf0f1a70476b8edc21439a1c2c01642e56a27aeba7418ef392199&amp;scene=21#wechat_redirect&quot;\" href=\"https:\/\/mp.weixin.qq.com\/s?__biz=MzAwMTEwNTc4OA==&amp;mid=2653513142&amp;idx=1&amp;sn=ad5410cfe6ebd55980aed0af2bf3bfa6&amp;chksm=81030fa5b67486b3743d4fbbf0f1a70476b8edc21439a1c2c01642e56a27aeba7418ef392199&amp;scene=21#wechat_redirect\" target=\"_blank\" rel=\"noopener noreferrer\" style=\"box-sizing: border-box;\"><\/p>\n<section style=\"margin-right: 0%;margin-bottom: 10px;margin-left: 0%;box-sizing: border-box;\">\n<section style=\"font-size: 14px;box-sizing: border-box;\">\n<p style=\"box-sizing: border-box;\">\u730e\u836f\u4eba\u98ce\u91c7\u4e4b\u590d\u65e6\u7bc7\uff1a\u59dc\u4e16\u52c3\u6559\u6388<\/p>\n<\/section>\n<\/section>\n<p><\/a><\/section>\n<section class=\"V5\" style=\"box-sizing: border-box;\" ><a title=\"https:\/\/mp.weixin.qq.com\/s?__biz=MzAwMTEwNTc4OA==&amp;mid=2653513060&amp;idx=1&amp;sn=dd77df4b1a06ccceb957bd092e946127&amp;chksm=81030f77b6748661e309d97a9b2fc223e4488cb3f4c3dc71b86a44599eb9faa02c9358bec984&amp;scene=21#wechat_redirect\" formlinkparm=\"&quot;https:\/\/mp.weixin.qq.com\/s?__biz=MzAwMTEwNTc4OA==&amp;mid=2653513060&amp;idx=1&amp;sn=dd77df4b1a06ccceb957bd092e946127&amp;chksm=81030f77b6748661e309d97a9b2fc223e4488cb3f4c3dc71b86a44599eb9faa02c9358bec984&amp;scene=21#wechat_redirect&quot;\" href=\"https:\/\/mp.weixin.qq.com\/s?__biz=MzAwMTEwNTc4OA==&amp;mid=2653513060&amp;idx=1&amp;sn=dd77df4b1a06ccceb957bd092e946127&amp;chksm=81030f77b6748661e309d97a9b2fc223e4488cb3f4c3dc71b86a44599eb9faa02c9358bec984&amp;scene=21#wechat_redirect\" target=\"_blank\" rel=\"noopener noreferrer\" style=\"box-sizing: border-box;\"><\/p>\n<section style=\"box-sizing: border-box;\">\n<section style=\"font-size: 14px;box-sizing: border-box;\">\n<p style=\"box-sizing: border-box;\">\u730e\u836f\u4eba\u98ce\u91c7\u4e4b\u4e0a\u6d77\u7bc7\uff1a\u623f\u5065\u6c11\u6559\u6388<\/p>\n<\/section>\n<\/section>\n<p><\/a><\/section>\n<section class=\"V5\" style=\"box-sizing: border-box;\" ><a title=\"https:\/\/mp.weixin.qq.com\/s?__biz=MzAwMTEwNTc4OA==&amp;mid=2653512948&amp;idx=1&amp;sn=c6901655bbcab34cce580759fefd0c85&amp;chksm=81030ee7b67487f17122813683a377cec8ef4e12e2ba7683e542669e223f8ffba04ead852a35&amp;scene=21#wechat_redirect\" formlinkparm=\"&quot;https:\/\/mp.weixin.qq.com\/s?__biz=MzAwMTEwNTc4OA==&amp;mid=2653512948&amp;idx=1&amp;sn=c6901655bbcab34cce580759fefd0c85&amp;chksm=81030ee7b67487f17122813683a377cec8ef4e12e2ba7683e542669e223f8ffba04ead852a35&amp;scene=21#wechat_redirect&quot;\" href=\"https:\/\/mp.weixin.qq.com\/s?__biz=MzAwMTEwNTc4OA==&amp;mid=2653512948&amp;idx=1&amp;sn=c6901655bbcab34cce580759fefd0c85&amp;chksm=81030ee7b67487f17122813683a377cec8ef4e12e2ba7683e542669e223f8ffba04ead852a35&amp;scene=21#wechat_redirect\" target=\"_blank\" rel=\"noopener noreferrer\" style=\"box-sizing: border-box;\"><\/p>\n<section style=\"margin: 10px 0%;box-sizing: border-box;\">\n<section style=\"font-size: 14px;box-sizing: border-box;\">\n<p style=\"box-sizing: border-box;\">\u730e\u836f\u4eba\u98ce\u91c7\u4e4b\u590d\u65e6\u7bc7\uff1a\u949f\u6625\u7396\u6559\u6388<\/p>\n<\/section>\n<\/section>\n<p><\/a><\/section>\n<section class=\"V5\" style=\"box-sizing: border-box;\" ><a title=\"https:\/\/mp.weixin.qq.com\/s?__biz=MzAwMTEwNTc4OA==&amp;mid=2653512820&amp;idx=1&amp;sn=2065967e39f55a4dc49ee9110ab75ae9&amp;chksm=81030e67b674877184029370860afd8e59d4e99a8dd3508197102e12e80aaadb7183dbdcb2aa&amp;scene=21#wechat_redirect\" formlinkparm=\"&quot;https:\/\/mp.weixin.qq.com\/s?__biz=MzAwMTEwNTc4OA==&amp;mid=2653512820&amp;idx=1&amp;sn=2065967e39f55a4dc49ee9110ab75ae9&amp;chksm=81030e67b674877184029370860afd8e59d4e99a8dd3508197102e12e80aaadb7183dbdcb2aa&amp;scene=21#wechat_redirect&quot;\" href=\"https:\/\/mp.weixin.qq.com\/s?__biz=MzAwMTEwNTc4OA==&amp;mid=2653512820&amp;idx=1&amp;sn=2065967e39f55a4dc49ee9110ab75ae9&amp;chksm=81030e67b674877184029370860afd8e59d4e99a8dd3508197102e12e80aaadb7183dbdcb2aa&amp;scene=21#wechat_redirect\" target=\"_blank\" rel=\"noopener noreferrer\" style=\"box-sizing: border-box;\"><\/p>\n<section style=\"box-sizing: border-box;\">\n<section style=\"font-size: 14px;box-sizing: border-box;\">\n<p style=\"box-sizing: border-box;\">\u730e\u836f\u4eba\u98ce\u91c7\u4e4b\u590d\u65e6\u7bc7\uff1a\u4f59\u79d1\u6559\u6388<\/p>\n<\/section>\n<\/section>\n<p><\/a><\/section>\n<section class=\"V5\" style=\"box-sizing: border-box;\" ><a title=\"https:\/\/mp.weixin.qq.com\/s?__biz=MzAwMTEwNTc4OA==&amp;mid=2653512750&amp;idx=1&amp;sn=6eb821c2e9b58d3afe129295edfd8ddf&amp;chksm=81030e3db674872b13fe47b68f3ec9419e604f0502a87c99d8c4d18a32475de8393eb68a7b9b&amp;scene=21#wechat_redirect\" formlinkparm=\"&quot;https:\/\/mp.weixin.qq.com\/s?__biz=MzAwMTEwNTc4OA==&amp;mid=2653512750&amp;idx=1&amp;sn=6eb821c2e9b58d3afe129295edfd8ddf&amp;chksm=81030e3db674872b13fe47b68f3ec9419e604f0502a87c99d8c4d18a32475de8393eb68a7b9b&amp;scene=21#wechat_redirect&quot;\" href=\"https:\/\/mp.weixin.qq.com\/s?__biz=MzAwMTEwNTc4OA==&amp;mid=2653512750&amp;idx=1&amp;sn=6eb821c2e9b58d3afe129295edfd8ddf&amp;chksm=81030e3db674872b13fe47b68f3ec9419e604f0502a87c99d8c4d18a32475de8393eb68a7b9b&amp;scene=21#wechat_redirect\" target=\"_blank\" rel=\"noopener noreferrer\" style=\"box-sizing: border-box;\"><\/p>\n<section style=\"margin: 10px 0%;box-sizing: border-box;\">\n<section style=\"font-size: 14px;box-sizing: border-box;\">\n<p style=\"box-sizing: border-box;\">\u730e\u836f\u4eba\u98ce\u91c7\u4e4b\u590d\u65e6\u7bc7\uff1a\u738b\u6c38\u8f89\u6559\u6388<\/p>\n<\/section>\n<\/section>\n<p><\/a><\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<p><br  \/><\/p>\n<section style=\"white-space: normal;background-color: rgb(255, 255, 255);box-sizing: border-box;\">\n<section class=\"Powered-by-XIUMI V5\"  style=\"box-sizing: border-box;\">\n<section class=\"\" style=\"box-sizing: border-box;\">\n<section class=\"\" style=\"padding-right: 10px;padding-left: 10px;font-size: 14px;line-height: 1.8;letter-spacing: 0.25px;box-sizing: border-box;\">\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;color: rgb(38, 43, 44);font-size: 12px;text-align: justify;word-wrap: break-word !important;\"><em><span style=\"color: rgb(136, 136, 136);\"><strong style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">&nbsp; &nbsp;\u91c7\u8bbf&amp;\u8d23\u7f16 |<\/strong><em style=\"color: rgb(38, 43, 44);\"><span style=\"color: rgb(136, 136, 136);\">&nbsp; \u674e\u660e\u3001\u5b54\u4ee4\u8f89<\/span><\/em><\/span><\/em><\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;color: rgb(38, 43, 44);font-size: 12px;text-align: justify;word-wrap: break-word !important;\"><em><span style=\"color: rgb(136, 136, 136);\"><strong style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">&nbsp; &nbsp;\u680f\u76ee\u4e3b\u7f16<\/strong>&nbsp;<strong style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">|&nbsp;<\/strong>\u5f90\u4e3d\u4e3d<\/span><\/em><\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;color: rgb(38, 43, 44);font-size: 12px;text-align: right;word-wrap: break-word !important;\"><span style=\"color: rgb(136, 136, 136);\"><span style=\"max-width: 100%;box-sizing: border-box;text-align: justify;word-wrap: break-word !important;\"><br  \/><\/span><\/span><\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;color: rgb(38, 43, 44);font-size: 12px;text-align: right;word-wrap: break-word !important;\"><span style=\"color: rgb(136, 136, 136);\"><span style=\"max-width: 100%;box-sizing: border-box;text-align: justify;word-wrap: break-word !important;\">&nbsp;\uff08\u70b9\u51fb\u5e95\u90e8<\/span><span style=\"text-align: justify;max-width: 100%;box-sizing: border-box;letter-spacing: 0px;word-wrap: break-word !important;\">\u201c\u9605\u8bfb\u539f\u6587\u201d<\/span><span style=\"max-width: 100%;box-sizing: border-box;letter-spacing: 0px;word-wrap: break-word !important;\"><span style=\"letter-spacing: 0.25px;text-align: justify;\">\u67e5\u770b<\/span><span style=\"text-align: justify;max-width: 100%;\">\u66f4\u591a\u91c7\u8bbf\u5185\u5bb9<\/span><\/span><span style=\"text-align: justify;\">\uff09<\/span><span style=\"letter-spacing: 0px;text-align: justify;\">&nbsp;<\/span><\/span><\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;color: rgb(38, 43, 44);font-size: 12px;text-align: right;word-wrap: break-word !important;\"><span style=\"max-width: 100%;box-sizing: border-box;letter-spacing: 0px;color: rgb(136, 136, 136);word-wrap: break-word !important;\">&nbsp;<span style=\"max-width: 100%;word-wrap: break-word !important;\">\uff08\u00a9 \u7248\u6743\u6240\u6709\uff0c\u5982\u9700\u8f6c\u8f7d\u8bf7\u8054\u7cfb\u6211\u4eec\u5e76\u8bf7\u6ce8\u660e\u51fa\u5904\uff09<\/span><\/span><\/p>\n<p style=\"box-sizing: border-box;\"><br  \/><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"Powered-by-XIUMI V5\"  style=\"white-space: normal;box-sizing: border-box;\">\n<section class=\"\" style=\"margin-bottom: 8px;box-sizing: border-box;\">\n<section class=\"\" style=\"margin-bottom: -10px;padding-right: 5px;padding-left: 5px;font-size: 18px;text-align: right;color: rgba(27, 27, 27, 0.882);line-height: 2.5;box-sizing: border-box;\">\n<p style=\"box-sizing: border-box;\"><strong style=\"box-sizing: border-box;\">Innovation&amp;Teamwork<\/strong><\/p>\n<\/section>\n<section class=\"\" style=\"width: 558.4px;height: 2em;line-height: 2em;display: inline-block;vertical-align: top;background-color: rgb(184, 54, 33);box-sizing: border-box;\">\n<section class=\"\" style=\"margin-left: 7.5em;white-space: nowrap;overflow: hidden;color: rgb(255, 255, 255);font-size: 12px;text-align: right;letter-spacing: 0px;box-sizing: border-box;\">\n<p style=\"box-sizing: border-box;\">\u6e90\u5934\u521b\u65b0 | \u534f\u540c\u8f6c\u5316 | \u77e5\u8bc6\u670d\u52a1&nbsp;<\/p>\n<\/section>\n<\/section>\n<section class=\"\" style=\"width: 558.4px;box-sizing: border-box;\">\n<section style=\"margin-top: -3.8em;margin-left: 1em;display: inline-block;vertical-align: top;width: 6em;box-sizing: border-box;\">\n<section class=\"\" style=\"width: 67.2px;display: inline-block;box-sizing: border-box;overflow: hidden !important;\"><\/section>\n<section class=\"\" style=\"width: 0px;display: inline-block;box-sizing: border-box;overflow: hidden !important;\"><img    width=\"100%\"  style=\"vertical-align: middle;width: 0px;box-sizing: border-box;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/08\/beepress1-1533788343.png\" alt=\"\u730e\u836f\u4eba\u98ce\u91c7\u4e4b\u590d\u65e6\u7bc7\uff1a\u6768\u9752\u6559\u6388\" title=\"\u730e\u836f\u4eba\u98ce\u91c7\u4e4b\u590d\u65e6\u7bc7\uff1a\u6768\u9752\u6559\u6388\"  \/><\/section>\n<\/section>\n<section class=\"group-empty\" style=\"padding-right: 5px;padding-left: 5px;display: inline-block;vertical-align: top;width: 10px;box-sizing: border-box;max-width: 60%;\">&nbsp;<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"Powered-by-XIUMI V5\"  style=\"white-space: normal;box-sizing: border-box;\">\n<section class=\"\" style=\"margin-top: -30px;box-sizing: border-box;\">\n<section class=\"\" style=\"text-align: center;line-height: 1.3;box-sizing: border-box;\">\n<p style=\"box-sizing: border-box;\"><strong style=\"box-sizing: border-box;\"><span style=\"font-size: 12px;box-sizing: border-box;\">\u4e0a\u6d77\u6d66\u4e1c\u5f20\u8861\u8def826\u53f7<\/span><\/strong><strong style=\"letter-spacing: 0px;box-sizing: border-box;\"><span style=\"font-size: 12px;letter-spacing: 0px;box-sizing: border-box;\">| 51980200|&nbsp;<\/span><\/strong><strong style=\"letter-spacing: 0px;box-sizing: border-box;\"><span style=\"font-size: 12px;letter-spacing: 0px;box-sizing: border-box;\">http:\/\/scd.fudan.edu.cn<\/span><\/strong><\/p>\n<p><br  \/><\/p>\n<\/section>\n<\/section>\n<\/section>\n<blockquote class='keep-source'>\n<p>\u59cb\u53d1\u4e8e\u5fae\u4fe1\u516c\u4f17\u53f7\uff1a                         \u4e0a\u6d77\u5e02\u836f\u7269\u7814\u53d1\u534f\u540c\u521b\u65b0\u4e2d\u5fc3                      <\/p>\n<\/blockquote>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>\u524d\u8a00 SCiDDD\u730e\u836f\u4eba\u98ce\u91c7 \u730e\uff0c\u4e00\u8bf4\u63fd\u4e5f\uff0c\u300a\u592a\u7384\u300b\u8c13\u4e4b\u6355\uff0c\u300a\u6cd5\u8a00\u300b\u8c13\u4e4b\u8ffd\u6c42\u4e5f\u3002\u836f\u5b66\u4eba\uff0c\u901a\u535a\u6570\u8f7d\uff0c\u5de5\u7814\u5176\u65b9\uff0c\u4e8e [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":31861,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[2],"tags":[],"_links":{"self":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/31860"}],"collection":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/comments?post=31860"}],"version-history":[{"count":1,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/31860\/revisions"}],"predecessor-version":[{"id":31876,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/31860\/revisions\/31876"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/media\/31861"}],"wp:attachment":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/media?parent=31860"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/categories?post=31860"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/tags?post=31860"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}