{"id":32350,"date":"2018-07-31T01:00:00","date_gmt":"2018-08-09T04:22:10","guid":{"rendered":"http:\/\/www.05921.net\/index.php\/2018\/08\/09\/%e4%bb%8e%e6%97%a0%e8%8d%af%e5%8f%af%e6%95%91%ef%bc%8c%e5%88%b0%e8%b5%b7%e6%ad%bb%e5%9b%9e%e7%94%9f%ef%bc%8cpd-1%e5%8f%88%e4%b8%80%e6%ac%a1%e5%a4%a7%e6%98%be%e7%a5%9e%e5%a8%81%ef%bc%81\/"},"modified":"2018-08-09T12:22:13","modified_gmt":"2018-08-09T04:22:13","slug":"%e4%bb%8e%e6%97%a0%e8%8d%af%e5%8f%af%e6%95%91%ef%bc%8c%e5%88%b0%e8%b5%b7%e6%ad%bb%e5%9b%9e%e7%94%9f%ef%bc%8cpd-1%e5%8f%88%e4%b8%80%e6%ac%a1%e5%a4%a7%e6%98%be%e7%a5%9e%e5%a8%81%ef%bc%81","status":"publish","type":"post","link":"https:\/\/www.05921.net\/index.php\/32350\/","title":{"rendered":"\u4ece\u65e0\u836f\u53ef\u6551\uff0c\u5230\u8d77\u6b7b\u56de\u751f\uff0cPD-1\u53c8\u4e00\u6b21\u5927\u663e\u795e\u5a01\uff01"},"content":{"rendered":"<div class=\"bpp-post-content\">\n<section style=\"font-size: 15px;line-height: 2;letter-spacing: 0.5px;padding: 0px 20px;color: rgb(86, 86, 102);box-sizing: border-box;\">\n<section class=\"Powered-by-XIUMI V5\" style=\"box-sizing: border-box;\" >\n<section class=\"\" style=\"text-align: center;margin-top: 10px;margin-bottom: 10px;box-sizing: border-box;\">\n<section class=\"\" style=\"max-width: 100%;vertical-align: middle;display: inline-block;border-width: 2px;border-radius: 5px;border-style: solid;border-color: rgb(70, 87, 114);overflow: hidden;box-sizing: border-box;\"><img    style=\"vertical-align: middle;max-width: 100%;box-sizing: border-box;\"  src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/08\/beepress5-1533788531.jpeg\" alt=\"\u4ece\u65e0\u836f\u53ef\u6551\uff0c\u5230\u8d77\u6b7b\u56de\u751f\uff0cPD-1\u53c8\u4e00\u6b21\u5927\u663e\u795e\u5a01\uff01\" title=\"\u4ece\u65e0\u836f\u53ef\u6551\uff0c\u5230\u8d77\u6b7b\u56de\u751f\uff0cPD-1\u53c8\u4e00\u6b21\u5927\u663e\u795e\u5a01\uff01\"  \/><\/section>\n<\/section>\n<\/section>\n<section class=\"Powered-by-XIUMI V5\" style=\"box-sizing: border-box;\" >\n<section class=\"\" style=\"box-sizing: border-box;\">\n<section class=\"\" style=\"font-size: 13px;color: rgb(142, 142, 154);box-sizing: border-box;\">\n<p style=\"margin: 0px;padding: 0px;box-sizing: border-box;\">\u6587\u4e28\u8f6c\u89d2\u7a7f\u68ad\u5b63\u8282<\/p>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"Powered-by-XIUMI V5\" style=\"box-sizing: border-box;\" >\n<section class=\"\" style=\"box-sizing: border-box;\">\n<section class=\"\" style=\"box-sizing: border-box;\">\n<p style=\"margin: 0px;padding: 0px;box-sizing: border-box;\"><br style=\"box-sizing: border-box;\"  \/><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"Powered-by-XIUMI V5\" style=\"box-sizing: border-box;\" >\n<section class=\"\" style=\"text-align: center;margin: 0px 0% 20px;box-sizing: border-box;\">\n<section class=\"\" style=\"max-width: 100%;vertical-align: middle;display: inline-block;width: 10%;border-width: 0px;box-shadow: rgb(0, 0, 0) 0px 0px 0px;box-sizing: border-box;\"><img    style=\"vertical-align: middle;max-width: 100%;width: 100%;box-sizing: border-box;\" width=\"100%\"  src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/08\/beepress0-1533788531.gif\" alt=\"\u4ece\u65e0\u836f\u53ef\u6551\uff0c\u5230\u8d77\u6b7b\u56de\u751f\uff0cPD-1\u53c8\u4e00\u6b21\u5927\u663e\u795e\u5a01\uff01\" title=\"\u4ece\u65e0\u836f\u53ef\u6551\uff0c\u5230\u8d77\u6b7b\u56de\u751f\uff0cPD-1\u53c8\u4e00\u6b21\u5927\u663e\u795e\u5a01\uff01\"  \/><\/section>\n<\/section>\n<\/section>\n<section class=\"Powered-by-XIUMI V5\" style=\"box-sizing: border-box;\" >\n<section class=\"\" style=\"box-sizing: border-box;\">\n<section class=\"\" style=\"text-align: justify;box-sizing: border-box;\">\n<p style=\"white-space: normal;margin: 0px;padding: 0px;box-sizing: border-box;\"><span style=\"color: rgb(197, 36, 36);font-size: 16px;box-sizing: border-box;\"><strong style=\"box-sizing: border-box;\">\u514d\u75ab\u6cbb\u7597<\/strong><\/span><span style=\"color: rgb(197, 36, 36);box-sizing: border-box;\"><strong style=\"box-sizing: border-box;\">&nbsp;<\/strong><\/span>\u8fd9\u4e2a\u8bcd\uff0c\u76f8\u4fe1\u5927\u5bb6\u5e94\u8be5\u90fd\u5f88\u719f\u6089\u4e86\u3002\u5728\u5b83\u7684\u5e2e\u52a9\u4e0b\uff0c\u5f88\u591a\u201c\u65e0\u836f\u53ef\u7528\u201d\u7684\u665a\u671f\u60a3\u8005\u53ef\u4ee5\u83b7\u5f97\u957f\u671f\u5e26\u7624\u751f\u5b58\u7684\u72b6\u6001\uff0c\u751a\u81f3\u8fbe\u5230\u4e34\u5e8a\u6cbb\u6108\u3002<\/p>\n<p style=\"white-space: normal;margin: 0px;padding: 0px;box-sizing: border-box;\"><br style=\"box-sizing: border-box;\"  \/><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"Powered-by-XIUMI V5\" style=\"box-sizing: border-box;\" >\n<section class=\"\" style=\"box-sizing: border-box;\">\n<section class=\"\" style=\"text-align: justify;box-sizing: border-box;\">\n<p style=\"white-space: normal;margin: 0px;padding: 0px;box-sizing: border-box;\">PD-1\u6291\u5236\u5242\u5728\u957f\u671f\u751f\u5b58\u7387\u548c\u526f\u4f5c\u7528\u65b9\u9762\u90fd\u6709\u7740\u4e0d\u9519\u7684\u8868\u73b0\uff0c\u54cd\u5e94PD-1\u514d\u75ab\u7597\u6cd5\u7684\u60a3\u8005\uff0c\u6709\u5f88\u5927\u7684\u6982\u7387\u53ef\u4ee5\u5b9e\u73b0\u9ad8\u8d28\u91cf\u957f\u671f\u5b58\u6d3b\u7684\u68a6\u60f3\uff0c\u8fd9\u6279\u66fe\u7ecf\u88ab\u5224\u6b7b\u5211\u7684\u665a\u671f\u764c\u75c7\u60a3\u8005\u901a\u5e38\u88ab\u79f0\u4e3a<span style=\"color: rgb(0, 121, 173);box-sizing: border-box;\"><strong style=\"box-sizing: border-box;\">\u201c\u8d85\u7ea7\u5e78\u5b58\u8005\u201d<\/strong><\/span>\uff01<\/p>\n<p style=\"white-space: normal;margin: 0px;padding: 0px;box-sizing: border-box;\"><br style=\"box-sizing: border-box;\"  \/><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"Powered-by-XIUMI V5\" style=\"box-sizing: border-box;\" >\n<section class=\"\" style=\"box-sizing: border-box;\">\n<section class=\"\" style=\"text-align: justify;box-sizing: border-box;\">\n<p style=\"white-space: normal;margin: 0px;padding: 0px;box-sizing: border-box;\">\u4f46\u51e1\u4e8b\u90fd\u6709\u4e24\u9762\u6027\uff0c\u795e\u836fPD-1\u5e76\u975e\u5c3d\u5584\u5c3d\u7f8e\uff0c\u5b83\u4e0d\u662f\u5bf9\u6240\u6709\u764c\u75c7\u60a3\u8005\u90fd\u6709\u6548\uff0c\u76ee\u524d\u4ec5\u5728\u4e00\u5c0f\u90e8\u5206\u60a3\u8005\u8eab\u4e0a\u770b\u5230\u4e86\u54cd\u5e94\u3002\u63d0\u9ad8PD-1\u7684\u6709\u6548\u7387\u8fd8\u6709\u5f88\u957f\u7684\u8def\u8981\u8d70\u3002<\/p>\n<p style=\"white-space: normal;margin: 0px;padding: 0px;box-sizing: border-box;\"><br style=\"box-sizing: border-box;\"  \/><\/p>\n<p style=\"white-space: normal;margin: 0px;padding: 0px;box-sizing: border-box;\">\u4eca\u5929\u4e3a\u5927\u5bb6\u5206\u4eab\u4e00\u4e2a&nbsp;<span style=\"color: rgb(197, 36, 36);box-sizing: border-box;\"><strong style=\"box-sizing: border-box;\">\u5b50\u5bab\u5185\u819c\u764c\u60a3\u8005\u4f7f\u7528PD-1\u7684\u6848\u4f8b<\/strong><\/span><span style=\"color: rgb(0, 121, 173);box-sizing: border-box;\"><strong style=\"box-sizing: border-box;\">&nbsp;<\/strong><\/span>,\u8fd9\u4e2a\u60a3\u8005\u90fd\u7ecf\u5386\u4e86\u4ec0\u4e48\u5462\uff1f\u8bf7\u5f80\u4e0b\u770b\uff1a<\/p>\n<p style=\"white-space: normal;margin: 0px;padding: 0px;box-sizing: border-box;\"><br style=\"box-sizing: border-box;\"  \/><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"Powered-by-XIUMI V5\" style=\"box-sizing: border-box;\" >\n<section class=\"\" style=\"box-sizing: border-box;\">\n<section class=\"\" style=\"text-align: justify;box-sizing: border-box;\">\n<p style=\"white-space: normal;margin: 0px;padding: 0px;box-sizing: border-box;\"><strong style=\"box-sizing: border-box;\">\u4e00\u4f4d42\u5c81\u7684\u5973\u6027\u60a3\u8005\uff0c<\/strong>2015\u5e741\u6708\u51fa\u73b0\u4e86\u4e0d\u89c4\u5219\u9634\u9053\u6d41\u8840\u7684\u75c7\u72b6\uff0c\u53bb\u533b\u9662\u68c0\u67e5\u53d1\u73b0\u662f\u5b50\u5bab\u5185\u819c\u764c\u3002<\/p>\n<p style=\"white-space: normal;margin: 0px;padding: 0px;box-sizing: border-box;\"><br style=\"box-sizing: border-box;\"  \/><\/p>\n<p style=\"white-space: normal;margin: 0px;padding: 0px;box-sizing: border-box;\">\u5979\u6700\u7ec8\u8fdb\u884c\u4e86\u8179\u8154\u955c\u5b50\u5bab\u5207\u9664\u672f\u548c\u53cc\u4fa7\u8f93\u5375\u7ba1\u5375\u5de2\u5207\u9664\u672f\uff0c\u75c5\u7406\u8bc1\u5b9e\u4e3a\u5b50\u5bab\u5185\u819c\u6837\u817a\u764c\uff0c\u4f34\u6709\u6dcb\u5df4\u548c\u8840\u7ba1\u7684\u4fb5\u72af\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"Powered-by-XIUMI V5\" style=\"box-sizing: border-box;\" >\n<section class=\"\" style=\"box-sizing: border-box;\">\n<section class=\"\" style=\"box-sizing: border-box;\">\n<p style=\"margin: 0px;padding: 0px;box-sizing: border-box;\"><br style=\"box-sizing: border-box;\"  \/><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"Powered-by-XIUMI V5\" style=\"box-sizing: border-box;\" >\n<section class=\"\" style=\"text-align: center;transform: translate3d(-2px, 0px, 0px);-webkit-transform: translate3d(-2px, 0px, 0px);-moz-transform: translate3d(-2px, 0px, 0px);-o-transform: translate3d(-2px, 0px, 0px);margin: 10px 0%;box-sizing: border-box;\">\n<section class=\"\" style=\"display: inline-block;min-width: 10%;max-width: 100%;vertical-align: top;background-color: rgb(255, 202, 0);padding: 0px;box-sizing: border-box;\">\n<section class=\"Powered-by-XIUMI V5\" style=\"box-sizing: border-box;\" >\n<section class=\"\" style=\"margin: 5px 0% -5px;transform: translate3d(5px, 0px, 0px);-webkit-transform: translate3d(5px, 0px, 0px);-moz-transform: translate3d(5px, 0px, 0px);-o-transform: translate3d(5px, 0px, 0px);box-sizing: border-box;\">\n<section class=\"\" style=\"display: inline-block;min-width: 10%;max-width: 100%;vertical-align: top;border-style: solid;border-width: 8px 1px 1px;border-radius: 0px;border-color: rgb(62, 62, 62);background-color: rgb(255, 255, 255);padding: 0px 8px;box-sizing: border-box;\">\n<section class=\"Powered-by-XIUMI V5\" style=\"box-sizing: border-box;\" >\n<section class=\"\" style=\"box-sizing: border-box;\">\n<section class=\"\" style=\"text-align: left;padding: 0px 8px;box-sizing: border-box;\">\n<p style=\"margin: 0px;padding: 0px;box-sizing: border-box;\"><em style=\"box-sizing: border-box;\"><strong style=\"box-sizing: border-box;\">\u75c5\u4f8b\u5206\u6790<\/strong><\/em><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"Powered-by-XIUMI V5\" style=\"box-sizing: border-box;\" >\n<section class=\"\" style=\"box-sizing: border-box;\">\n<section class=\"\" style=\"box-sizing: border-box;\">\n<p style=\"margin: 0px;padding: 0px;box-sizing: border-box;\"><br style=\"box-sizing: border-box;\"  \/><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"Powered-by-XIUMI V5\" style=\"box-sizing: border-box;\" >\n<section class=\"\" style=\"box-sizing: border-box;\">\n<section class=\"\" style=\"text-align: justify;box-sizing: border-box;\">\n<p style=\"white-space: normal;margin: 0px;padding: 0px;box-sizing: border-box;\"><span style=\"color: rgb(0, 121, 173);box-sizing: border-box;\"><strong style=\"box-sizing: border-box;\">2015\u5e743\u6708\uff0c<\/strong><\/span>\u5979\u63a5\u53d7\u4e86<strong style=\"box-sizing: border-box;\">\u76c6\u8154\u548c\u4e3b\u52a8\u8109\u65c1\u6dcb\u5df4\u7ed3\u6e05\u626b\u672f\u4ee5\u53ca\u9634\u9053\u80bf\u5757\u5207\u9664\u672f<\/strong>\u3002<\/p>\n<p style=\"white-space: normal;margin: 0px;padding: 0px;box-sizing: border-box;\"><br style=\"box-sizing: border-box;\"  \/><\/p>\n<p style=\"white-space: normal;margin: 0px;padding: 0px;box-sizing: border-box;\">\u6700\u7ec8\u75c5\u7406\u663e\u793a\uff0c\u6240\u6709\u6dcb\u5df4\u7ed3\u5747\u4e3a\u9634\u6027;\u9634\u9053\u80bf\u5757\u75c5\u7406\u5207\u7247\u663e\u793a\u5b50\u5bab\u5185\u819c\u6837\u817a\u764c\uff0cMSH2\u548cMSH6\u8868\u8fbe\u7f3a\u5931\uff0c\u4e0edMMR\u9519\u914d\u4fee\u590d\u7f3a\u9677<span style=\"color: rgb(142, 142, 154);box-sizing: border-box;\">\uff08\u9519\u914d\u4fee\u590d\u7f3a\u9677\uff09<\/span>\u4e00\u81f4\u3002<\/p>\n<p style=\"white-space: normal;margin: 0px;padding: 0px;box-sizing: border-box;\"><br style=\"box-sizing: border-box;\"  \/><\/p>\n<p style=\"white-space: normal;margin: 0px;padding: 0px;box-sizing: border-box;\">\u4e00\u4e2a\u6708\u540e\uff0c\u5f71\u50cf\u5b66\u663e\u793a\uff0c\u60a3\u8005\u7684\u53f3\u4fa7\u8179\u76f4\u808c\u548c\u8110\u90e8\u51fa\u73b0\u4e86\u8f6c\u79fb\u3002\u4f7f\u7528\u4e86\u6fc0\u7d20\u548c\u4ed6\u83ab\u6614\u82ac\uff0c\u4f46\u6ca1\u6709\u63a7\u5236\u4f4f\u8f6c\u79fb\u7076\u7684\u8fdb\u5c55\u3002\u4e4b\u540e\u5bf9\u8f6c\u79fb\u7076\u8fdb\u884c\u4e86\u653e\u7597\u3002<\/p>\n<p style=\"white-space: normal;margin: 0px;padding: 0px;box-sizing: border-box;\"><br style=\"box-sizing: border-box;\"  \/><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"Powered-by-XIUMI V5\" style=\"box-sizing: border-box;\" >\n<section class=\"\" style=\"box-sizing: border-box;\">\n<section class=\"\" style=\"text-align: justify;box-sizing: border-box;\">\n<p style=\"white-space: normal;margin: 0px;padding: 0px;box-sizing: border-box;\"><span style=\"color: rgb(0, 121, 173);box-sizing: border-box;\"><strong style=\"box-sizing: border-box;\">2016\u5e745\u6708\uff0c<\/strong><\/span>\u5f71\u50cf\u5b66\u68c0\u67e5\u53d1\u73b0\uff0c\u4f1a\u9634\u90e8\u51fa\u73b0\u4e86\u65b0\u7684\u8f6c\u79fb\u75c5\u7076\u3002\u4e4b\u524d\u4f7f\u7528\u7684\u5316\u7597\u548c\u653e\u7597\u672a\u80fd\u63a7\u5236\u75c5\u60c5\u7684\u590d\u53d1\u3002<\/p>\n<p style=\"white-space: normal;margin: 0px;padding: 0px;box-sizing: border-box;\"><br style=\"box-sizing: border-box;\"  \/><\/p>\n<p style=\"white-space: normal;margin: 0px;padding: 0px;box-sizing: border-box;\">\u6b64\u65f6\u91cd\u65b0\u8fdb\u884c\u6d3b\u7ec4\u7ec7\u68c0\u67e5\uff0c\u53d1\u73b0\u80bf\u7624\u5df2\u7ecf\u53bb\u5206\u5316\u6210\u9ad8\u7ea7Mullerian\u817a\u764c\u3002\u514d\u75ab\u7ec4\u7ec7\u5316\u5b66\u67d3\u8272\u518d\u6b21\u8bc1\u5b9eMSH2\u548cMSH6\u7684\u8868\u8fbe\u4e27\u5931\uff0c\u4e0e\u539f\u53d1\u7076\u7684\u68c0\u67e5\u7ed3\u679c\u4e00\u81f4\u3002\u9274\u4e8e\u8fd9\u4e9b\u53d1\u73b0\uff0c\u533b\u751f\u5efa\u8bae\u60a3\u8005\u8fdb\u884c\u57fa\u56e0\u68c0\u6d4b\u4ee5\u8fdb\u884c\u57fa\u56e0\u7ec4\u5206\u6790\u3002<\/p>\n<p style=\"white-space: normal;margin: 0px;padding: 0px;box-sizing: border-box;\"><br style=\"box-sizing: border-box;\"  \/><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"Powered-by-XIUMI V5\" style=\"box-sizing: border-box;\" >\n<section class=\"\" style=\"text-align: center;margin: 10px 0% 0px;box-sizing: border-box;\">\n<section class=\"\" style=\"max-width: 100%;vertical-align: middle;display: inline-block;box-sizing: border-box;\"><img    style=\"vertical-align: middle;max-width: 100%;box-sizing: border-box;\"  src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/08\/beepress3-1533788531.jpg\" alt=\"\u4ece\u65e0\u836f\u53ef\u6551\uff0c\u5230\u8d77\u6b7b\u56de\u751f\uff0cPD-1\u53c8\u4e00\u6b21\u5927\u663e\u795e\u5a01\uff01\" title=\"\u4ece\u65e0\u836f\u53ef\u6551\uff0c\u5230\u8d77\u6b7b\u56de\u751f\uff0cPD-1\u53c8\u4e00\u6b21\u5927\u663e\u795e\u5a01\uff01\"  \/><\/section>\n<\/section>\n<\/section>\n<section class=\"Powered-by-XIUMI V5\" style=\"box-sizing: border-box;\" >\n<section class=\"\" style=\"box-sizing: border-box;\">\n<section class=\"\" style=\"text-align: center;font-size: 14px;box-sizing: border-box;\">\n<p style=\"margin: 0px;padding: 0px;box-sizing: border-box;\">\u56fe1<\/p>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"Powered-by-XIUMI V5\" style=\"box-sizing: border-box;\" >\n<section class=\"\" style=\"box-sizing: border-box;\">\n<section class=\"\" style=\"box-sizing: border-box;\">\n<p style=\"margin: 0px;padding: 0px;box-sizing: border-box;\"><br style=\"box-sizing: border-box;\"  \/><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"Powered-by-XIUMI V5\" style=\"box-sizing: border-box;\" >\n<section class=\"\" style=\"box-sizing: border-box;\">\n<section class=\"\" style=\"text-align: justify;box-sizing: border-box;\">\n<p style=\"white-space: normal;margin: 0px;padding: 0px;box-sizing: border-box;\">\u57fa\u56e0\u68c0\u6d4b\u6570\u636e\u8868\u660e\uff0c<span style=\"color: rgb(0, 121, 173);box-sizing: border-box;\"><strong style=\"box-sizing: border-box;\">\u60a3\u8005\u5728BRCA1\u548cBRCA2\u4e2d\u5177\u6709\u81f4\u75c5\u7a81\u53d8\u3002<\/strong><\/span>\u56e0\u4e3a\u4e24\u79cd\u53d8\u4f53\u4f3c\u4e4e\u90fd\u662f\u6742\u5408\u7684\uff0c\u9884\u8ba1\u80bf\u7624\u6291\u5236\u56e0\u5b50\u4e0d\u4f1a\u5b8c\u5168\u5931\u6d3b\u3002<\/p>\n<p style=\"white-space: normal;margin: 0px;padding: 0px;box-sizing: border-box;\"><br style=\"box-sizing: border-box;\"  \/><\/p>\n<p style=\"white-space: normal;margin: 0px;padding: 0px;box-sizing: border-box;\">\u63a8\u6d4b\u8fd9\u4e24\u79cd\u57fa\u56e0\u7684\u90e8\u5206\u7f3a\u5931\uff0c\u53ef\u80fd\u4f1a\u5bfc\u81f4BRCA\u4fee\u590d\u9014\u5f84\u7684\u6d3b\u6027\u964d\u4f4e\uff0c\u5e76\u8fdb\u4e00\u6b65\u4fc3\u8fdb\u80bf\u7624\u65b0\u6297\u539f\u7684\u4ea7\u751f<span style=\"color: rgb(142, 142, 154);box-sizing: border-box;\">\uff08\u56fe2\uff09<\/span><\/p>\n<p style=\"white-space: normal;margin: 0px;padding: 0px;box-sizing: border-box;\"><br style=\"box-sizing: border-box;\"  \/><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"Powered-by-XIUMI V5\" style=\"box-sizing: border-box;\" >\n<section class=\"\" style=\"text-align: center;margin-top: 10px;margin-bottom: 10px;box-sizing: border-box;\">\n<section class=\"\" style=\"max-width: 100%;vertical-align: middle;display: inline-block;box-sizing: border-box;\"><img    style=\"vertical-align: middle;max-width: 100%;box-sizing: border-box;\"  src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/08\/beepress2-1533788531.jpg\" alt=\"\u4ece\u65e0\u836f\u53ef\u6551\uff0c\u5230\u8d77\u6b7b\u56de\u751f\uff0cPD-1\u53c8\u4e00\u6b21\u5927\u663e\u795e\u5a01\uff01\" title=\"\u4ece\u65e0\u836f\u53ef\u6551\uff0c\u5230\u8d77\u6b7b\u56de\u751f\uff0cPD-1\u53c8\u4e00\u6b21\u5927\u663e\u795e\u5a01\uff01\"  \/><\/section>\n<\/section>\n<\/section>\n<section class=\"Powered-by-XIUMI V5\" style=\"box-sizing: border-box;\" >\n<section class=\"\" style=\"box-sizing: border-box;\">\n<section class=\"\" style=\"text-align: center;font-size: 14px;box-sizing: border-box;\">\n<p style=\"margin: 0px;padding: 0px;box-sizing: border-box;\">\u56fe2<\/p>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"Powered-by-XIUMI V5\" style=\"box-sizing: border-box;\" >\n<section class=\"\" style=\"box-sizing: border-box;\">\n<section class=\"\" style=\"box-sizing: border-box;\">\n<p style=\"margin: 0px;padding: 0px;box-sizing: border-box;\"><br style=\"box-sizing: border-box;\"  \/><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"Powered-by-XIUMI V5\" style=\"box-sizing: border-box;\" >\n<section class=\"\" style=\"box-sizing: border-box;\">\n<section class=\"\" style=\"text-align: justify;box-sizing: border-box;\">\n<p style=\"white-space: normal;margin: 0px;padding: 0px;box-sizing: border-box;\">\u9274\u4e8e\u60a3\u8005\u4e0d\u80fd\u8010\u53d7\u987a\u94c2\u4f5c\u4e3a\u653e\u5c04\u589e\u654f\u5242\uff0c\u5168\u8eab\u6cbb\u7597\u5e76\u4e0d\u4e00\u5b9a\u662f\u4e00\u79cd\u5b89\u5168\u7684\u9009\u62e9\u3002\u8fd9\u4f4d\u60a3\u8005\u5bf9\u653e\u7597\u7684\u6548\u679c\u4e0d\u662f\u592a\u597d\uff0c\u5e76\u4e14\u624b\u672f\u7684\u5c1d\u8bd5\u8bc1\u660e\u662f\u65e0\u6548\u7684\u3002<\/p>\n<p style=\"white-space: normal;margin: 0px;padding: 0px;box-sizing: border-box;\"><br style=\"box-sizing: border-box;\"  \/><\/p>\n<p style=\"white-space: normal;margin: 0px;padding: 0px;box-sizing: border-box;\">\u5728\u6700\u540e\u4e00\u6b21\u6cbb\u7597\u7684\u5c1d\u8bd5\u4e2d\uff0c\u60a3\u8005\u4e8e2016\u5e746\u6708\u5f00\u59cb\u4f7f\u7528\u6d3e\u59c6\u5355\u6297\uff08\u6bcf3\u5468\u670d\u7528\u4e00\u6b21\uff0c\u6bcf\u6b212 mg \/ kg\uff09\u3002<strong style=\"box-sizing: border-box;\">\u5728\u7b2c\u4e00\u6b21\u6cbb\u7597\u540e\uff0c\u68c0\u67e5\u53d1\u73b0\u5979\u7684\u80bf\u7624\u7f29\u5c0f\u4e8630\uff05\uff0c\u5e76\u4e14\u5728\u7b2c\u4e09\u5468\u671f\u5f00\u59cb\u65f6\uff0c\u60a3\u8005\u7684\u75bc\u75db\u75c7\u72b6\u5b8c\u5168\u6d88\u9000\u3002<\/strong><\/p>\n<p style=\"white-space: normal;margin: 0px;padding: 0px;box-sizing: border-box;\"><br style=\"box-sizing: border-box;\"  \/><\/p>\n<p style=\"white-space: normal;margin: 0px;padding: 0px;box-sizing: border-box;\"><strong style=\"box-sizing: border-box;\">\u56db\u4e2a\u5468\u671f\u540e\uff0c\u5f71\u50cf\u5b66\u68c0\u67e5\u663e\u793a\u60a3\u8005\u7684\u80bf\u7624\u75c5\u7076\u5b8c\u5168\u6d88\u9000\u3002\u5728\u6cbb\u7597\u5f00\u59cb\u540e\u768413\u4e2a\u6708\uff0c\u60a3\u8005\u4ecd\u7136\u5904\u4e8e\u7f13\u89e3\u671f\uff0c\u75be\u75c5\u6ca1\u6709\u53d1\u751f\u8fdb\u5c55\u3002<\/strong><\/p>\n<p style=\"white-space: normal;margin: 0px;padding: 0px;box-sizing: border-box;\"><br style=\"box-sizing: border-box;\"  \/><\/p>\n<p style=\"white-space: normal;margin: 0px;padding: 0px;box-sizing: border-box;\">\u5bf9\u60a3\u8005\u6765\u8bf4\uff0c\u5386\u7ecf\u574e\u5777\u540e\uff0c\u7ec8\u4e8e\u627e\u5230\u4e86\u751f\u5b58\u4e0b\u53bb\u7684\u5e0c\u671b\u3002<\/p>\n<p style=\"white-space: normal;margin: 0px;padding: 0px;box-sizing: border-box;\"><br style=\"box-sizing: border-box;\"  \/><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"Powered-by-XIUMI V5\" style=\"box-sizing: border-box;\" >\n<section class=\"\" style=\"box-sizing: border-box;\">\n<section class=\"\" style=\"text-align: justify;box-sizing: border-box;\">\n<p style=\"white-space: normal;margin: 0px;padding: 0px;box-sizing: border-box;\">\u5728\u8fd9\u4e2a\u5177\u6709\u4fb5\u88ad\u6027\u5b50\u5bab\u5185\u819c\u764c\u7684BRCA1\u7a81\u53d8\u643a\u5e26\u8005\u7684\u75c5\u4f8b\u4e2d\uff0cPD-1\u6291\u5236\u5242\u663e\u793a\u51fa\u4e86\u8fc5\u901f\u548c\u6301\u7eed\u7684\u6548\u679c\u3002<\/p>\n<p style=\"white-space: normal;margin: 0px;padding: 0px;box-sizing: border-box;\"><br style=\"box-sizing: border-box;\"  \/><\/p>\n<p style=\"white-space: normal;margin: 0px;padding: 0px;box-sizing: border-box;\">\u5728\u5979\u7684MMR\u7f3a\u9677\u80bf\u7624\u4e2d\u51fa\u73b0\u7684BRCA2\u53d8\u5f02\u53ef\u80fd\u5bfc\u81f4BRCA\u4fee\u590d\u9014\u5f84\u7684\u90e8\u5206\u635f\u4f24\u3002<\/p>\n<p style=\"white-space: normal;margin: 0px;padding: 0px;box-sizing: border-box;\"><br style=\"box-sizing: border-box;\"  \/><\/p>\n<p style=\"white-space: normal;margin: 0px;padding: 0px;box-sizing: border-box;\">\u8fd9\u79cd\u7ec4\u5408\u53ef\u4ee5\u89e3\u91ca\u4e3a\u4ec0\u4e48\u8fd9\u4f4d\u60a3\u8005\u5bf9PD-1\u6291\u5236\u5242\u6709\u6548\u3002\u8fd9\u4e2a\u6848\u4f8b\u4e5f\u7ed9\u4e86\u6211\u4eec\u4e00\u4e9b\u53c2\u8003\uff0c<span style=\"color: rgb(0, 121, 173);box-sizing: border-box;\"><strong style=\"box-sizing: border-box;\">\u5373\u4f7f\u5728\u9047\u5230\u201c\u65e0\u836f\u53ef\u7528\u201d\u7684\u60c5\u51b5\u4e0b\uff0c\u4e5f\u4e0d\u8981\u653e\u5f03\u5bf9\u751f\u5b58\u4e0b\u53bb\u7684\u6e34\u671b\u3002<\/strong><\/span><\/p>\n<p style=\"white-space: normal;margin: 0px;padding: 0px;box-sizing: border-box;\"><br style=\"box-sizing: border-box;\"  \/><\/p>\n<p style=\"white-space: normal;margin: 0px;padding: 0px;box-sizing: border-box;\">\u8fd9\u4e00\u6b21\uff0cPD-1\u6291\u5236\u5242\u518d\u4e00\u6b21\u626e\u6f14\u4e86\u6551\u4e16\u4e3b\u7684\u89d2\u8272\uff0c\u628a\u90a3\u4f4d\u60a3\u8005\u4ece\u6b7b\u4ea1\u7684\u8fb9\u7f18\u62c9\u4e86\u56de\u6765\uff0c\u4e0d\u7981\u8ba9\u4eba\u611f\u53f9PD-1\u7684\u795e\u5947\u548c\u60a3\u8005\u7684\u5e78\u8fd0\uff01<\/p>\n<p style=\"white-space: normal;margin: 0px;padding: 0px;box-sizing: border-box;\"><br style=\"box-sizing: border-box;\"  \/><\/p>\n<p style=\"white-space: normal;margin: 0px;padding: 0px;box-sizing: border-box;\"><strong style=\"box-sizing: border-box;\">\u4eca\u5929\u7684\u6587\u732e\u94fe\u63a5\uff0c\u53ef\u4ee5\u5728\u540e\u53f0\u79c1\u4fe120180731\u83b7\u53d6\u3002<\/strong><\/p>\n<p style=\"white-space: normal;margin: 0px;padding: 0px;box-sizing: border-box;\"><br style=\"box-sizing: border-box;\"  \/><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"Powered-by-XIUMI V5\" style=\"box-sizing: border-box;\" >\n<section class=\"\" style=\"box-sizing: border-box;\">\n<section class=\"\" style=\"text-align: justify;font-size: 12px;color: rgb(142, 142, 154);box-sizing: border-box;\">\n<p style=\"white-space: normal;margin: 0px;padding: 0px;box-sizing: border-box;\"><strong style=\"box-sizing: border-box;\">\u539f\u59cb\u6587\u732e\u6765\u6e90\uff1a<\/strong><\/p>\n<p style=\"white-space: normal;margin: 0px;padding: 0px;box-sizing: border-box;\">DON S. DIZON\uff0cComplete Remission Following Pembrolizumab in a Woman with Mismatch Repair-Deficient Endometrial Cancer and a Germline BRCA1 Mutation\uff0cFebruary 26, 2018\uff0cthe oncologist<br style=\"box-sizing: border-box;\"  \/><\/p>\n<p style=\"white-space: normal;margin: 0px;padding: 0px;box-sizing: border-box;\"><br style=\"box-sizing: border-box;\"  \/><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"Powered-by-XIUMI V5\" style=\"box-sizing: border-box;\" >\n<section class=\"\" style=\"text-align: center;margin: 30px 0% 10px;box-sizing: border-box;\">\n<section class=\"\" style=\"max-width: 100%;vertical-align: middle;display: inline-block;width: 60%;box-sizing: border-box;\"><img    style=\"vertical-align: middle;max-width: 100%;width: 100%;box-sizing: border-box;\" width=\"100%\"  src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/08\/beepress10-1533788532.png\" alt=\"\u4ece\u65e0\u836f\u53ef\u6551\uff0c\u5230\u8d77\u6b7b\u56de\u751f\uff0cPD-1\u53c8\u4e00\u6b21\u5927\u663e\u795e\u5a01\uff01\" title=\"\u4ece\u65e0\u836f\u53ef\u6551\uff0c\u5230\u8d77\u6b7b\u56de\u751f\uff0cPD-1\u53c8\u4e00\u6b21\u5927\u663e\u795e\u5a01\uff01\"  \/><\/section>\n<\/section>\n<\/section>\n<section class=\"Powered-by-XIUMI V5\" style=\"box-sizing: border-box;\" >\n<section class=\"\" style=\"margin: 0px 0% 10px;box-sizing: border-box;\">\n<section class=\"\" style=\"font-size: 14px;letter-spacing: 5px;color: rgb(70, 87, 114);box-sizing: border-box;\">\n<p style=\"text-align: center;margin: 0px;padding: 0px;box-sizing: border-box;\"><strong style=\"box-sizing: border-box;\">\u764c\u5ea6\u670d\u52a1\u9879\u76ee<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"Powered-by-XIUMI V5\" style=\"box-sizing: border-box;\" ><a class=\"\" title=\"https:\/\/mp.weixin.qq.com\/s?__biz=MzI4MzIxOTU2Mw==&amp;mid=2247491418&amp;idx=2&amp;sn=4040ba15fcaa58666fc32660d89e0ecf&amp;scene=21#wechat_redirect\" formlinkparm=\"&quot;https:\/\/mp.weixin.qq.com\/s?__biz=MzI4MzIxOTU2Mw==&amp;mid=2247491418&amp;idx=2&amp;sn=4040ba15fcaa58666fc32660d89e0ecf&amp;scene=21#wechat_redirect&quot;\" href=\"https:\/\/mp.weixin.qq.com\/s?__biz=MzI4MzIxOTU2Mw==&amp;mid=2247491418&amp;idx=2&amp;sn=4040ba15fcaa58666fc32660d89e0ecf&amp;scene=21#wechat_redirect\" target=\"_blank\" rel=\"noopener noreferrer\" style=\"box-sizing: border-box;\"><\/p>\n<section class=\"\" style=\"text-align: center;margin: 10px 0% 20px;box-sizing: border-box;\">\n<section class=\"\" style=\"max-width: 100%;vertical-align: middle;display: inline-block;border-width: 2px;border-radius: 5px;border-style: groove;border-color: rgb(250, 250, 250);box-shadow: rgb(250, 250, 250) 0px 0px 0px;width: 90%;overflow: hidden;box-sizing: border-box;\"><span class=\"js_jump_icon h5_image_link\"  style=\"top: auto;left: auto;margin: 0px;right: auto;bottom: auto;\"><img    style=\"vertical-align: middle;max-width: 100%;width: 100%;box-sizing: border-box;margin: 0px;\" width=\"100%\"  src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/08\/beepress0-1533788532.jpeg\" alt=\"\u4ece\u65e0\u836f\u53ef\u6551\uff0c\u5230\u8d77\u6b7b\u56de\u751f\uff0cPD-1\u53c8\u4e00\u6b21\u5927\u663e\u795e\u5a01\uff01\" title=\"\u4ece\u65e0\u836f\u53ef\u6551\uff0c\u5230\u8d77\u6b7b\u56de\u751f\uff0cPD-1\u53c8\u4e00\u6b21\u5927\u663e\u795e\u5a01\uff01\"  \/><\/span><\/section>\n<\/section>\n<p><\/a><\/section>\n<section class=\"Powered-by-XIUMI V5\" style=\"box-sizing: border-box;\" ><a class=\"\" title=\"https:\/\/mp.weixin.qq.com\/s?__biz=MzI4MzIxOTU2Mw==&amp;mid=2247491418&amp;idx=3&amp;sn=661f3278d33b756a3cdb900f25cfe734&amp;scene=21#wechat_redirect\" formlinkparm=\"&quot;https:\/\/mp.weixin.qq.com\/s?__biz=MzI4MzIxOTU2Mw==&amp;mid=2247491418&amp;idx=3&amp;sn=661f3278d33b756a3cdb900f25cfe734&amp;scene=21#wechat_redirect&quot;\" href=\"https:\/\/mp.weixin.qq.com\/s?__biz=MzI4MzIxOTU2Mw==&amp;mid=2247491418&amp;idx=3&amp;sn=661f3278d33b756a3cdb900f25cfe734&amp;scene=21#wechat_redirect\" target=\"_blank\" rel=\"noopener noreferrer\" style=\"box-sizing: border-box;\"><\/p>\n<section class=\"\" style=\"text-align: center;margin: 10px 0% 20px;box-sizing: border-box;\">\n<section class=\"\" style=\"max-width: 100%;vertical-align: middle;display: inline-block;border-width: 2px;border-radius: 5px;border-style: groove;border-color: rgb(250, 250, 250);box-shadow: rgb(0, 0, 0) 0px 0px 0px;width: 90%;overflow: hidden;box-sizing: border-box;\"><span class=\"js_jump_icon h5_image_link\"  style=\"top: auto;left: auto;margin: 0px;right: auto;bottom: auto;\"><\/span><\/section>\n<\/section>\n<p><\/a><\/section>\n<section class=\"Powered-by-XIUMI V5\" style=\"box-sizing: border-box;\" ><a class=\"\" title=\"https:\/\/mp.weixin.qq.com\/s?__biz=MzI4MzIxOTU2Mw==&amp;mid=2247491418&amp;idx=4&amp;sn=8554f6083df09d133b6d218e6bc5443f&amp;scene=21#wechat_redirect\" formlinkparm=\"&quot;https:\/\/mp.weixin.qq.com\/s?__biz=MzI4MzIxOTU2Mw==&amp;mid=2247491418&amp;idx=4&amp;sn=8554f6083df09d133b6d218e6bc5443f&amp;scene=21#wechat_redirect&quot;\" href=\"https:\/\/mp.weixin.qq.com\/s?__biz=MzI4MzIxOTU2Mw==&amp;mid=2247491418&amp;idx=4&amp;sn=8554f6083df09d133b6d218e6bc5443f&amp;scene=21#wechat_redirect\" target=\"_blank\" rel=\"noopener noreferrer\" style=\"box-sizing: border-box;\"><\/p>\n<section class=\"\" style=\"text-align: center;margin: 10px 0% 20px;box-sizing: border-box;\">\n<section class=\"\" style=\"max-width: 100%;vertical-align: middle;display: inline-block;border-width: 2px;border-radius: 5px;border-style: groove;border-color: rgb(250, 250, 250);box-shadow: rgb(0, 0, 0) 0px 0px 0px;width: 90%;overflow: hidden;box-sizing: border-box;\"><span class=\"js_jump_icon h5_image_link\"  style=\"top: auto;left: auto;margin: 0px;right: auto;bottom: auto;\"><img    style=\"vertical-align: middle;max-width: 100%;width: 100%;box-sizing: border-box;margin: 0px;\" width=\"100%\"  src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/08\/beepress4-1533788532.jpeg\" alt=\"\u4ece\u65e0\u836f\u53ef\u6551\uff0c\u5230\u8d77\u6b7b\u56de\u751f\uff0cPD-1\u53c8\u4e00\u6b21\u5927\u663e\u795e\u5a01\uff01\" title=\"\u4ece\u65e0\u836f\u53ef\u6551\uff0c\u5230\u8d77\u6b7b\u56de\u751f\uff0cPD-1\u53c8\u4e00\u6b21\u5927\u663e\u795e\u5a01\uff01\"  \/><\/span><\/section>\n<\/section>\n<p><\/a><\/section>\n<\/section>\n<blockquote class='keep-source'>\n<p>\u59cb\u53d1\u4e8e\u5fae\u4fe1\u516c\u4f17\u53f7\uff1a                         \u764c\u5ea6                      <\/p>\n<\/blockquote>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>\u6587\u4e28\u8f6c\u89d2\u7a7f\u68ad\u5b63\u8282 \u514d\u75ab\u6cbb\u7597&nbsp;\u8fd9\u4e2a\u8bcd\uff0c\u76f8\u4fe1\u5927\u5bb6\u5e94\u8be5\u90fd\u5f88\u719f\u6089\u4e86\u3002\u5728\u5b83\u7684\u5e2e\u52a9\u4e0b\uff0c\u5f88\u591a\u201c\u65e0\u836f\u53ef\u7528\u201d\u7684\u665a\u671f\u60a3\u8005 [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":32351,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[2],"tags":[],"_links":{"self":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/32350"}],"collection":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/comments?post=32350"}],"version-history":[{"count":1,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/32350\/revisions"}],"predecessor-version":[{"id":32363,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/32350\/revisions\/32363"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/media\/32351"}],"wp:attachment":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/media?parent=32350"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/categories?post=32350"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/tags?post=32350"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}