{"id":37526,"date":"2018-08-22T01:00:00","date_gmt":"2018-09-17T06:13:50","guid":{"rendered":"http:\/\/www.05921.net\/index.php\/2018\/09\/17\/be%e7%a0%94%e7%a9%b6%e6%8e%a8%e8%8d%90%e8%af%bb%e8%af%bb%e8%bf%99%e5%87%a0%e6%9c%ac%e4%b9%a6\/"},"modified":"2018-09-17T14:13:58","modified_gmt":"2018-09-17T06:13:58","slug":"be%e7%a0%94%e7%a9%b6%e6%8e%a8%e8%8d%90%e8%af%bb%e8%af%bb%e8%bf%99%e5%87%a0%e6%9c%ac%e4%b9%a6","status":"publish","type":"post","link":"https:\/\/www.05921.net\/index.php\/37526\/","title":{"rendered":"BE\u7814\u7a76,\u63a8\u8350\u8bfb\u8bfb\u8fd9\u51e0\u672c\u4e66"},"content":{"rendered":"
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\"BE\u7814\u7a76,\u63a8\u8350\u8bfb\u8bfb\u8fd9\u51e0\u672c\u4e66\"<\/section>\n
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\u5916\u8d44\u5927\u578b\u5236\u836f\u516c\u53f8\u6280\u672f\u3001\u7814\u53d1\u3001\u8d28\u91cf\u603b\u76d1\uff0c\u9a8c\u8bc1\u7ba1\u7406\u8d44\u6df1\u4e13\u5bb6\uff0c\u591a\u5bb6\u5236\u836f\u516c\u53f8\u987e\u95ee\uff0c\u836f\u5b66\u7855\u58eb\u3002\u56fd\u5bb6\u5de5\u827a\u6838\u5bf9\u672a\u96e8\u7ef8\u7f2a\u4e4b\u9645\uff0c\u6210\u529f\u89e3\u51b3\u4e86\u591a\u5bb6\u5728\u4ea7\u4ea7\u54c1\u5904\u65b9\u3001\u5de5\u827a\u95ee\u9898\u3002\u5904\u65b9\u5de5\u827a\u7684\u4e8c\u6b21\u5f00\u53d1\uff0c\u514d\u8d39\u54a8\u8be2\uff0c\u5168\u7a0b\u4fdd\u5bc6\u3002\u90ae\u7bb1\uff1a1193686015@qq.com\u3002<\/span><\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

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\u7f16\u8005\u8bed\uff1a\u968f\u7740\u4e00\u81f4\u6027\u8bc4\u4ef7\u6df1\u5165\u8fdb\u884c\uff0c\u5f88\u591a\u5382\u5bb6\u5df2\u7ecf\u5b8c\u6210\u4e86BE\u7814\u7a76\u548c\u6b63\u5728\u8fdb\u884cBE\u8bd5\u9a8c\u3002\u4e3a\u4e86\u5bf9BE\u8bd5\u9a8c\u6709\u5168\u9762\u8ba4\u8bc6\u548c\u4e86\u89e3\uff0c\u63a8\u8350\u540c\u884c\u8bfb\u8bfb\u4ee5\u4e0b\u8fd9\u51e0\u672c\u4e66\u3002<\/span><\/p>\n


<\/p>\n

\u7b2c\u4e00\u672c\uff1aFDA\u751f\u7269\u7b49\u6548\u6027\u6807\u51c6\uff082014\u5e74\u7248\uff09<\/span><\/strong><\/p>\n

\"BE\u7814\u7a76,\u63a8\u8350\u8bfb\u8bfb\u8fd9\u51e0\u672c\u4e66\"<\/p>\n


<\/p>\n

FDA\u751f\u7269\u7b49\u6548\u6027\u6807\u51c6\u7531<\/span>FDA<\/span>\u76d1\u7ba1\u79d1\u5b66\u5bb6\u7f16\u5199\uff0c\u4ed6\u4eec\u5236\u5b9a\u76d1\u7ba1\u653f\u7b56\u5e76\u5bf9\u751f\u7269\u7b49\u6548\u6027\u8fdb\u884c\u76d1\u7ba1\u8bc4\u4f30\u3002\u56e0\u6b64\uff0c\u8fd9\u4e9b\u7ae0\u8282\u90fd\u5f3a\u8c03\u4e86\u5b9e\u8df5\u6848\u4f8b\u7814\u7a76\u548c\u57fa\u7840\u79d1\u5b66\u3002\u672c\u4e66\u5bf9\u4e8e\u5728\u5236\u836f\u884c\u4e1a\uff0c\u76d1\u7ba1\u673a\u6784\u548c\u5b66\u672f\u754c\u5de5\u4f5c\u7684\u79d1\u5b66\u5bb6\u4ee5\u53ca\u5e0c\u671b\u6269\u5c55\u751f\u7269\u7b49\u6548\u6027\u6807\u51c6\u77e5\u8bc6\u7684\u672c\u79d1\u751f\u548c\u7814\u7a76\u751f\u6765\u8bf4\u662f\u5b9d\u8d35\u7684\u8d44\u6e90\u3002\u672c\u4e66\u5f88\u591a\u540c\u884c\u8d2d\u4e70\u4e86\u4e2d\u6587\u7248\u9605\u8bfb\u3002\u662f\u975e\u5e38\u4e0d\u9519\u7684\u4e00\u672c\u4e66\u3002<\/span><\/span><\/p>\n


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\u7b2c\u4e8c\u672c \uff1a\u751f\u7269\u7b49\u6548\u6027\u5b9e\u9a8c\u624b\u518c\uff08\u7b2c\u4e8c\u7248\uff09<\/span><\/strong><\/p>\n

\u4f5c\u8005\uff08S\uff09\uff1aSarfaraz K Niazi
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\u51fa\u7248\u5546\uff1a\u6cf0\u52d2\u548c\u5f17\u6717\u897f\u65af\uff0cCRC\u51fa\u7248\u793e<\/span><\/strong><\/p>\n

\"BE\u7814\u7a76,\u63a8\u8350\u8bfb\u8bfb\u8fd9\u51e0\u672c\u4e66\"<\/span><\/strong><\/p>\n

<\/span><\/strong><\/p>\n

\u7814\u5982\u7389\u7ffb\u8bd1\u56e2\u961f\u7ecf\u8fc7\u534a\u5e74\u7684\u52aa\u529b\u628a\u300a\u751f\u7269\u7b49\u6548\u6027\u8bd5\u9a8c\u624b\u518c\u300b\u7ffb\u8bd1\u5b8c\u6bd5\u3002\u5c11\u91cf\u7ffb\u8bd1\u7a3f\u5df2\u7ecf\u8d60\u9001\u7ed9\u90e8\u5206\u540c\u884c\u5171\u4eab\u3002<\/span><\/strong><\/p>\n

\"BE\u7814\u7a76,\u63a8\u8350\u8bfb\u8bfb\u8fd9\u51e0\u672c\u4e66\"<\/p>\n

 <\/span>
<\/p>\n

\u968f\u7740\u4eff\u5236\u836f\u884c\u4e1a\u7684\u4e0d\u65ad\u53d1\u5c55\u548c\u58ee\u5927\uff0c\u9700\u8981\u5f00\u5c55\u5145\u5206\uff0c\u9ad8\u6548\u7684\u751f\u7269\u7b49\u6548\u6027\u7814\u7a76\u3002\u8fd1\u5e74\u6765\uff0c\u8bc4\u4f30\u751f\u7269\u7b49\u6548\u6027\u7684\u7edf\u8ba1\u6a21\u578b\u53d1\u751f\u4e86\u91cd\u5927\u53d8\u5316\u3002\u6b64\u5916\uff0c\u7528\u4e8e\u68c0\u6d4b\u836f\u7269\u548c\u4ee3\u8c22\u7269\u6c34\u5e73\u7684\u5206\u6790\u6280\u672f\u7684\u8fdb\u6b65\u4f7f\u751f\u7269\u7b49\u6548\u6027\u6d4b\u8bd5\u66f4\u52a0\u590d\u6742\u3002<\/span>\u201c\u751f\u7269\u7b49\u6548\u6027\u6d4b\u8bd5\u624b\u518c\u201d\u7b2c\u4e8c\u7248\u5df2\u7ecf\u5b8c\u5168\u66f4\u65b0\uff0c\u5305\u62ec\u6700\u65b0\u7684\u4fe1\u606f\uff0c\u5305\u62ec\u836f\u7269\u8f93\u9001\u548c\u5242\u578b\u8bbe\u8ba1\u548c\u4fee\u6539\u7684\u65b0\u53d1\u73b0\u3002<\/span><\/p>\n


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\u76ee\u5f55<\/span> <\/span>\uff1a<\/span><\/span><\/p>\n

\u7b2c\u4e00\u7ae0 \u4eff\u5236\u836f\u7684\u5386\u53f2\u56de\u987e <\/span><\/p>\n

\u7b2c\u4e8c\u7ae0 \u751f\u7269\u7b49\u6548\u6027\u8bd5\u9a8c\u7684\u7406\u5316\u57fa\u7840<\/span><\/p>\n

\u7b2c\u4e09\u7ae0 \u836f\u7269\u9012\u9001\u56e0\u7d20<\/span><\/p>\n

\u7b2c\u56db\u7ae0 \u836f\u4ee3\u52a8\u529b\u5b66\/\u836f\u6548\u5b66\uff08PKPD\uff09\u5efa\u6a21<\/span><\/p>\n

\u7b2c\u4e94\u7ae0 \u751f\u7269\u7b49\u6548\u6027\u8bd5\u9a8c\u539f\u7406\u548c\u539f\u5219<\/span><\/p>\n

\u7b2c\u516d\u7ae0 \u751f\u7269\u7b49\u6548\u6027\u7684\u8c41\u514d<\/span><\/p>\n

\u7b2c\u4e03\u7ae0 \u751f\u7269\u7b49\u6548\u6027\u6570\u636e\u7684\u7edf\u8ba1\u8bc4\u4f30<\/span><\/p>\n

\u7b2c\u516b\u7ae0 \u76d1\u7763\u76d1\u5bdf\u6d41\u7a0b335<\/span><\/p>\n

\u7b2c\u4e5d\u7ae0 \u9910\u540e\u751f\u7269\u7b49\u6548\u6027\u8bd5\u9a8c<\/span><\/p>\n

\u7b2c\u5341\u7ae0 \u5c40\u90e8\u7528\u836f<\/span><\/p>\n

\u7b2c\u5341\u4e00\u7ae0 \u9f3b\u7528\u836f\u7269\u7684\u751f\u7269\u7b49\u6548\u6027<\/span><\/p>\n

\u7b2c\u5341\u4e8c\u7ae0 \u8865\u5145\u548c\u66ff\u4ee3\u836f\u7269\u7684\u751f\u7269\u7b49\u6548\u6027<\/span><\/p>\n

\u7b2c\u5341\u4e09\u7ae0 \u751f\u836f\u4eff\u5236\u836f\u751f\u7269\u7b49\u6548\u6027<\/span><\/p>\n

\u7b2c\u5341\u56db\u7ae0 \u751f\u7269\u7b49\u6548\u6027\u8bd5\u9a8c\uff1a\u7f8e\u56fd\u89c2\u70b9<\/span><\/p>\n

\u7b2c\u5341\u4e94\u7ae0 \u751f\u7269\u7b49\u6548\u6027\u8bd5\u9a8c\uff1a\u6b27\u6d32\u89c2\u70b9<\/span><\/p>\n

\u7b2c\u5341\u516d\u7ae0 \u751f\u7269\u7b49\u6548\u6027\u8bd5\u9a8c\u884c\u4e1a\u900f\u89c6<\/span><\/p>\n

\u7b2c\u5341\u4e03\u7ae0 \u751f\u7269\u7b49\u6548\u6027\u8bd5\u9a8c\u65b9\u6848<\/span><\/p>\n

\u7b2c\u5341\u516b\u7ae0 \u751f\u7269\u7b49\u6548\u6027\u6587\u4ef6<\/span><\/p>\n

\u7b2c\u5341\u4e5d\u7ae0 \u836f\u7269\u975e\u4e34\u5e8a\u7814\u7a76\u8d28\u91cf\u7ba1\u7406\u89c4\u8303\uff08GLP\uff09<\/span><\/p>\n

\u7b2c\u4e8c\u5341\u7ae0 \u751f\u7269\u5206\u6790\u65b9\u6cd5\u5b66\u9a8c\u8bc1<\/span><\/p>\n

\u7b2c\u4e8c\u5341\u4e00\u7ae0 \u836f\u7269\u4e34\u5e8a\u8bd5\u9a8c\u8d28\u91cf\u7ba1\u7406\u89c4\u8303(GCP)<\/span><\/p>\n

\u7b2c\u4e8c\u5341\u4e8c\u7ae0 \u7535\u8111\u548c\u8f6f\u4ef6\u9a8c\u8bc1<\/span><\/p>\n

\u7b2c\u4e8c\u5341\u4e09\u7ae0 \u751f\u7269\u7b49\u6548\u6027\u7814\u7a76\u7684\u5916\u5305\u548c\u76d1\u6d4b<\/span><\/p>\n

\u7b2c\u4e8c\u5341\u56db\u7ae0 \u751f\u7269\u7b49\u6548\u6027\u8bd5\u9a8c\u7684\u672a\u6765<\/span><\/p>\n

\u9644\u5f55<\/span>A<\/span>\uff1a\u672f\u8bed\u8868<\/span>; <\/span><\/span>\u9644\u5f55<\/span>B<\/span>\uff1a\u7f8e\u56fd<\/span>FDA<\/span>\u63d0\u4ea4\u7684\u6eb6\u51fa\u5ea6\u6d4b\u8bd5\u8981\u6c42<\/span>; <\/span><\/span>\u53c2\u8003\u4e66\u76ee<\/span>; <\/span><\/span>\u5c01\u5e95 <\/span>
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\u7b2c\u4e09\u672c\uff1a\u4e34\u5e8a\u836f\u7406\u5b66\u4e2d\u7684\u751f\u7269\u7b49\u6548\u6027\u548c\u7edf\u8ba1\u5b66\uff0c\u7b2c\u4e8c\u7248<\/span><\/strong><\/p>\n

\u743c\u65af\uff0c\u62dc\u4f26; \u5e15\u7279\u68ee\uff0c\u65af\u79d1\u7279D.<\/span><\/strong><\/p>\n

\u51fa\u7248\u5546\uff1a\u67e5\u666e\u66fc\u548c\u970d\u5c14\/ CRC\uff0cCRC\u51fa\u7248\u793e<\/span><\/strong><\/p>\n


<\/p>\n

\"BE\u7814\u7a76,\u63a8\u8350\u8bfb\u8bfb\u8fd9\u51e0\u672c\u4e66\"<\/p>\n

\u743c\u65af\uff0c\u62dc\u4f26; \u5e15\u7279\u68ee\uff0c\u65af\u79d1\u7279D.<\/span><\/strong><\/p>\n

\u51fa\u7248\u5546\uff1a\u67e5\u666e\u66fc\u548c\u970d\u5c14\/ CRC\uff0cCRC\u51fa\u7248\u793e<\/span><\/strong><\/p>\n

 <\/span><\/p>\n

\u4fdd\u6301\u5b9e\u7528\u7684\u89c2\u70b9\uff0c\u4e34\u5e8a\u836f\u7406\u5b66\u4e2d\u7684\u751f\u7269\u7b49\u6548\u6027\u548c\u7edf\u8ba1\u5b66\uff0c\u7b2c\u4e8c\u7248\u63a2\u8ba8\u4e86\u65e5\u5e38\u4e34\u5e8a\u836f\u7406\u5b66\u5de5\u4f5c\u4e2d\u4f7f\u7528\u7684\u7edf\u8ba1\u5b66\u3002\u672c\u4e66\u662f\u53c2\u4e0e\u6b64\u7c7b\u7814\u7a76\u7684\u4eba\u5458\u7684\u8d77\u70b9\uff0c\u6db5\u76d6\u8bbe\u8ba1\uff0c\u5206\u6790\u548c\u89e3\u91ca\u751f\u7269\u7b49\u6548\u6027\u8bd5\u9a8c\u6240\u9700\u7684\u65b9\u6cd5<\/span>; <\/span>\u63a2\u8ba8\u8fd9\u4e9b\u7814\u7a76\u4f55\u65f6\uff0c\u5982\u4f55\u4ee5\u53ca\u4e3a\u4f55\u4f5c\u4e3a\u836f\u7269\u5f00\u53d1\u7684\u4e00\u90e8\u5206\u8fdb\u884c<\/span>; <\/span><\/span>\u5e76\u6f14\u793a\u4f7f\u7528\u771f\u5b9e\u4e16\u754c\u793a\u4f8b\u7684\u65b9\u6cd5\u3002<\/span><\/span><\/p>\n

 <\/span><\/p>\n

\u5229\u7528\u4ece\u5236\u836f\u884c\u4e1a\u76f4\u63a5\u83b7\u5f97\u7684\u77e5\u8bc6\uff0c\u4f5c\u8005\u901a\u8fc7\u63cf\u8ff0\u7edf\u8ba1\u7684\u4e00\u822c\u4f5c\u7528\u6765\u8bbe\u5b9a\u9636\u6bb5\u3002\u4e00\u65e6\u5efa\u7acb\u4e86\u4e34\u5e8a\u836f\u7406\u5b66\u836f\u7269\u5f00\u53d1\uff0c\u76d1\u7ba1\u5e94\u7528\u4ee5\u53ca\u751f\u7269\u7b49\u6548\u6027\u8bd5\u9a8c\u7684\u8bbe\u8ba1\u548c\u5206\u6790\u7684\u57fa\u7840\uff0c\u5305\u62ec\u6700\u8fd1\u5728\u8bbe\u8ba1\u548c\u5206\u6790\u65b9\u9762\u7684\u76d1\u7ba1\u53d8\u5316\uff0c\u7279\u522b\u662f\u6837\u672c\u5927\u5c0f\u9002\u5e94\uff0c\u4ed6\u4eec\u8f6c\u5411\u6d89\u53ca\u4e34\u5e8a\u836f\u7406\u5b66\u7684\u76f8\u5173\u4e3b\u9898\u3002\u4f7f\u7528\u4ea4\u53c9\u8bbe\u8ba1\u3002\u8fd9\u4e9b\u5305\u62ec\u4f46\u4e0d\u9650\u4e8e<\/span>I\u671f\u5b89\u5168\u6027\u7814\u7a76\uff0c\u5242\u91cf\u53cd\u5e94\u8bd5\u9a8c\uff0c\u836f\u7269\u76f8\u4e92\u4f5c\u7528\u8bd5\u9a8c\uff0c\u98df\u7269\u6548\u5e94\u548c\u8054\u5408\u8bd5\u9a8c\uff0c<\/span>QTc<\/span>\u548c\u5176\u4ed6\u836f\u6548\u5b66\u7b49\u6548\u8bd5\u9a8c\uff0c\u6982\u5ff5\u9a8c\u8bc1\u8bd5\u9a8c\uff0c\u5242\u91cf\u6bd4\u4f8b\u8bd5\u9a8c\uff0c\u548c\u75ab\u82d7\u8bd5\u9a8c\u3002<\/span><\/span><\/p>\n

 <\/span><\/p>\n

\u672c\u7b2c\u4e8c\u7248\u4ecb\u7ecd\u4e86\u8be5\u9886\u57df\u7684\u51e0\u9879\u6700\u65b0\u53d1\u5c55\uff0c\u5305\u62ec\u9002\u5e94\u6027\u751f\u7269\u7b49\u6548\u6027\u7814\u7a76\uff0c\u89c4\u6a21\u5e73\u5747\u751f\u7269\u7b49\u6548\u6027\u6d4b\u8bd5\u548c\u75ab\u82d7\u8bd5\u9a8c\u7684\u65b0\u7ae0\u8282\u3002<\/span><\/span><\/p>\n

 <\/span> <\/span><\/p>\n

\u6709\u9488\u5bf9\u6027\u5730\u8bbe\u8ba1\u4e3a\u5373\u523b\u9002\u7528\uff0c\u4e34\u5e8a\u836f\u7406\u5b66\u751f\u7269\u7b49\u6548\u6027\u548c\u7edf\u8ba1\u5b66\uff0c\u7b2c\u4e8c\u7248\u63d0\u4f9b\u4e86<\/span>SAS\u548c<\/span>R<\/span>\u4ee3\u7801\u7684\u4f8b\u5b50\uff0c\u4ee5\u4fbf\u6240\u63cf\u8ff0\u7684\u5206\u6790\u53ef\u4ee5\u7acb\u5373\u5b9e\u65bd\u3002\u4f5c\u8005\u5e7f\u6cdb\u4f7f\u7528\u4e86<\/span>SAS<\/span>\u4e2d\u53ef\u7528\u7684<\/span>proc<\/span>\u6df7\u5408\u7a0b\u5e8f\u3002<\/span><\/span><\/p>\n

\u76ee\u5f55\uff1a<\/span><\/span><\/p>\n

\u5185\u5bb9\uff1a<\/span><\/span><\/p>\n

1\u3001\u751f\u7269\u7b49\u6548\u6027\u548c\u751f\u7269\u5236\u836f\u5f00\u53d1 <\/span><\/span>–<\/span><\/span><\/p>\n

2\u3001\u751f\u7269\u7b49\u6548\u6027\u4e13\u9898 <\/span><\/span>–<\/span><\/span><\/p>\n

3\u3001\u4e34\u5e8a\u836f\u7406\u5b66 <\/span><\/span>–<\/span><\/span><\/p>\n

4\u3001\u75ab\u82d7\u548c\u7ed3\u8bed <\/span><\/span>–<\/span><\/span><\/p>\n

5\u3001\u53c2\u8003\u4e66\u76ee\u3002<\/span><\/span><\/p>\n

\u80fd\u4ed4\u7ec6\u628a\u8fd9\u51e0\u672c\u4e66\u8bfb\u5b8c\u8bfb\u61c2\u5e76\u7406\u89e3\u548c\u9886\u4f1a\uff0c\u771f\u5f97\u8981\u82b1\u70b9\u65f6\u95f4\uff0c\u4e0b\u6b21\u6211\u7ed9\u5927\u5bb6\u518d\u4ecb\u7ecd\u51e0\u672c\u4e66\u8bfb\u3002<\/span><\/strong><\/p>\n

\u7b2c\u56db\u672c\uff1a\u836f\u7269\u5f00\u53d1\u4e2d\u7684\u751f\u7269\u7b49\u6548\u6027\u7814\u7a76 <\/span><\/strong><\/p>\n


<\/span><\/strong><\/p>\n

\"BE\u7814\u7a76,\u63a8\u8350\u8bfb\u8bfb\u8fd9\u51e0\u672c\u4e66\"<\/p>\n

\u4f5c\u8005\uff1aDieter hauschke\u3001Volker Steinigi\u3001Iris Pistina <\/span><\/strong><\/h3>\n

\u51fa\u7248\u5546\uff1aWiley  \u9875\u6570\uff1a328  \u53d1\u5e03\u65e5\u671f\uff1a2007-03-16 <\/span><\/strong>
<\/p>\n


<\/p>\n

   \u751f\u7269\u7b49\u6548\u6027\u7814\u7a76\u662f\u8bc1\u660e\u4e24\u79cd\u836f\u7269\u4e4b\u95f4\u6cbb\u7597\u7b49\u6548\u6027\u7684\u5e38\u7528\u65b9\u6cd5\u3002 \u5f53\u4f7f\u7528\u751f\u7269\u7b49\u6548\u6027\u4f5c\u4e3a\u6cbb\u7597\u7b49\u6548\u6027\u7684\u5efa\u7acb\u66ff\u4ee3\u6807\u8bb0\u65f6\uff0c\u65f6\u95f4\u548c\u6210\u672c\u7684\u8282\u7ea6\u662f\u76f8\u5f53\u5927\u7684\u3002 \u51fa\u4e8e\u8fd9\u4e00\u539f\u56e0\uff0c\u751f\u7269\u7b49\u6548\u6027\u7814\u7a76\u7684\u8bbe\u8ba1\u3001\u6027\u80fd\u548c\u8bc4\u4ef7\u53d7\u5230\u5b66\u672f\u754c\u3001\u5236\u836f\u884c\u4e1a\u548c\u536b\u751f\u5f53\u5c40\u7684\u5e7f\u6cdb\u5173\u6ce8\u3002 <\/span><\/p>\n


<\/p>\n

   \u836f\u7269\u5f00\u53d1\u751f\u7269\u7b49\u6548\u6027\u7814\u7a76\u96c6\u4e2d\u4e8e\u751f\u7269\u7b49\u6548\u6027\u7814\u7a76\u7684\u89c4\u5212\u3001\u4f20\u5bfc\u3001\u5206\u6790\u548c\u62a5\u544a\uff0c\u6db5\u76d6\u76d1\u7ba1\u673a\u6784\u8981\u6c42\u7684\u6240\u6709\u65b9\u9762\u3002 \u672c\u6587\u4ecb\u7ecd\u4e86\u6240\u9700\u7684\u7edf\u8ba1\u65b9\u6cd5\uff0c\u5e76\u5177\u6709\u7a81\u51fa\u7684\u5b9e\u9645\u91cd\u70b9\uff0c\u901a\u8fc7\u8bb8\u591a\u5b9e\u4f8b\u5c55\u793a\u4e86\u5b83\u4eec\u7684\u5e94\u7528\uff0c\u4f7f\u7528\u4e86\u6765\u81ea\u836f\u7269\u5f00\u53d1\u7684\u771f\u5b9e\u6570\u636e\u3002 <\/span><\/p>\n


<\/p>\n

\u5305\u62ec\u6240\u6709\u5fc5\u8981\u7684\u836f\u4ee3\u52a8\u529b\u5b66\u80cc\u666f\u4fe1\u606f\u3002 <\/span><\/p>\n

\u7ed9\u51fa\u4e86\u53c2\u6570\u548c\u975e\u53c2\u6570\u7edf\u8ba1\u6280\u672f\u3002 <\/span><\/p>\n

\u63cf\u8ff0\u4e86\u8db3\u591f\u7684\u529f\u7387\u548c\u6837\u672c\u91cf\u786e\u5b9a\u65b9\u6cd5\u3002 <\/span><\/p>\n

\u5305\u62ec\u9002\u5f53\u5448\u73b0\u751f\u7269\u7b49\u6548\u6027\u7814\u7a76\u7684\u7ed3\u679c\u3002 <\/span><\/p>\n

\u63d0\u4f9b\u751f\u7269\u7b49\u6548\u6027\u7814\u7a76\u7684\u8bbe\u8ba1\u548c\u5206\u6790\u7684\u5b9e\u9645\u6982\u8ff0\u3002 <\/span><\/p>\n

\u4ecb\u7ecd\u4e86\u65b9\u6cd5\u5b66\u4e0a\u6700\u8fd1\u7684\u8fdb\u5c55\uff0c\u5305\u62ec\u4eba\u53e3\u548c\u4e2a\u4f53\u751f\u7269\u7b49\u6548\u6027\u3002 <\/span><\/p>\n

\u5ba1\u67e5\u6b64\u7c7b\u7814\u7a76\u7684\u76d1\u7ba1\u6307\u5357\uff0c\u4ee5\u53ca\u73b0\u6709\u7684\u5168\u7403\u5dee\u5f02\u3002 <\/span><\/p>\n

\u8ba8\u8bba\u4e86\u836f\u7269-\u836f\u7269\u76f8\u4e92\u4f5c\u7528\u7814\u7a76\u7684\u8bbe\u8ba1\u548c\u5206\u6790\u3002 <\/span><\/p>\n

\u836f\u7269\u5f00\u53d1\u4e2d\u7684\u751f\u7269\u7b49\u6548\u6027\u7814\u7a76\u4ee5\u53ef\u8bbf\u95ee\u7684\u65b9\u5f0f\u4e66\u5199\uff0c\u4f7f\u5f97\u836f\u7269\u79d1\u5b66\u5bb6\u3001\u4e34\u5e8a\u836f\u7406\u5b66\u5bb6\u548c\u533b\u5b66\u4ece\u4e1a\u8005\u4ee5\u53ca\u5728\u5236\u836f\u5de5\u4e1a\u4e2d\u5de5\u4f5c\u7684\u751f\u7269\u8ba1\u91cf\u533b\u5e08\u90fd\u662f\u7406\u60f3\u7684\u3002 \u8bc4\u4f30\u751f\u7269\u7b49\u6548\u6027\u7814\u7a76\u7684\u76d1\u7ba1\u673a\u6784\u7684\u4e13\u4e1a\u4eba\u5458\u4e5f\u6709\u5f88\u5927\u7684\u4ef7\u503c\u3002 <\/span><\/p>\n

\"BE\u7814\u7a76,\u63a8\u8350\u8bfb\u8bfb\u8fd9\u51e0\u672c\u4e66\"<\/p>\n


<\/span><\/strong><\/p>\n

\u7b2c\u4e94\u672c\uff1a\u5168\u7403\u53f8\u6cd5\u7ba1\u8f96\u533a\u7684\u5404\u79cd\u751f\u7269\u7b49\u6548\u6027\u8981\u6c42<\/span><\/strong>
<\/p>\n\n\n\n

<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

\"BE\u7814\u7a76,\u63a8\u8350\u8bfb\u8bfb\u8fd9\u51e0\u672c\u4e66\"
<\/p>\n


<\/span><\/p>\n

   \u5c3d\u7ba1\u8bb8\u591a\u5168\u7403\u53f8\u6cd5\u7ba1\u8f96\u533a\u7684\u751f\u7269\u7b49\u6548\u6027\uff08BE\uff09\u8981\u6c42\u6709\u8bb8\u591a\u5171\u540c\u4e4b\u5904\uff0c\u4f46\u67d0\u4e9b\u65b9\u6cd5\u548c\u8981\u6c42\uff08\u5982\u5b9a\u4e49\u548c\u672f\u8bed\uff0c\u6bd4\u8f83\uff08\u53c2\u8003\uff09\u4ea7\u54c1\u7684\u9009\u62e9\uff0c\u9a8c\u6536\u6807\u51c6\uff0c\u7981\u98df\u548c\u9972\u6599\u7814\u7a76\uff0c\u5355\u5242\u91cf\u548c\u591a\u5242\u91cf\u7814\u7a76\uff0c\u4e0d\u6253\u7b97\u5438\u6536\u5230\u4f53\u5faa\u73af\u4e2d\u7684\u751f\u7269\u5242\u548c\u4ea7\u54c1\uff08\u5c40\u90e8\u65bd\u7528\u836f\u7269\u548c\u5242\u578b\uff09\u7b49\u7b49\uff0c\u63d0\u4f9b\u4e86\u4e00\u79cd\u601d\u60f3\uff0c\u8ba4\u4e3a\u6807\u51c6\u5316\u5e94\u8be5\u662f\u4e00\u4e2a\u9ad8\u5ea6\u4f18\u5148\u7684\u76ee\u6807\uff0c\u4ee5\u4fbf\u5f62\u6210\u4e00\u4e2a\u7edf\u4e00\u7684\u56fd\u9645\u7a0b\u5e8f\uff0c\u4ee5\u83b7\u5f97\u5e02\u573a\u6279\u51c6\u4ea7\u54c1\u4f7f\u7528BE<\/span>\u3002\u5404\u79cd\u5168\u7403\u53f8\u6cd5\u7ba1\u8f96\u533a\u4e2d\u751f\u7269\u7b49\u6548\u6027\u8981\u6c42\u7684\u4e00\u4e2a\u91cd\u8981\u76ee\u6807\u662f\u5c1d\u8bd5\u6536\u96c6\u4e0d\u540c\u5168\u7403\u53f8\u6cd5\u7ba1\u8f96\u533a\u4e2d\u4f7f\u7528\u7684\u5404\u79cdBE<\/span>\u8981\u6c42\uff0c\u4ee5\u63d0\u4f9b\u76f8\u5173\u4fe1\u606f\u7684\u5355\u4e00\u6765\u6e90\u3002<\/span><\/p>\n

 <\/span><\/p>\n

   \u7f8e\u56fd\u548c\u4e16\u754c\u536b\u751f\u7ec4\u7ec7\u5c06\u5bf9\u836f\u54c1\u5236\u9020\u5546\uff0c\u76d1\u7ba1\u673a\u6784\uff0c\u5236\u836f\u79d1\u5b66\u5bb6\u4ee5\u53ca\u76f8\u5173\u536b\u751f\u7ec4\u7ec7\u548c\u4e16\u754c\u5404\u56fd\u653f\u5e9c\u6709\u4ef7\u503c\uff0c\u4ee5\u534f\u8c03\u5bf9\u901a\u7528\u4ea7\u54c1\u5e02\u573a\u6279\u51c6\u7684\u76d1\u7ba1\u8981\u6c42\u3002<\/span><\/p>\n


<\/p>\n

\u7b2c\u516d\u672c\uff1a\u4eff\u5236\u836f\u4ea7\u54c1\u5f00\u53d1\uff1a\u751f\u7269\u7b49\u6548\u6027\u7684\u56fd\u9645\u76d1\u7ba1\u8981\u6c42<\/span><\/strong><\/p>\n

 <\/span><\/p>\n

\"BE\u7814\u7a76,\u63a8\u8350\u8bfb\u8bfb\u8fd9\u51e0\u672c\u4e66\"<\/p>\n


<\/p>\n

sadore Kanfer\uff08\u7f16\u8f91\uff09\uff0cLeon Shargel\uff08\u7f16\u8f91\uff09<\/span><\/strong><\/p>\n

\u51fa\u7248\u5546\uff1aInforma\u533b\u7597\u4fdd\u5065<\/span><\/strong>
<\/p>\n

  <\/span><\/p>\n

  \u7531\u4e8e\u5168\u7403\u5bf9\u4f4e\u6210\u672c\u836f\u7269\u6cbb\u7597\u7684\u9700\u6c42\uff0c\u901a\u7528\u548c\u591a\u6e90\u836f\u7269\u4ea7\u54c1\u7684\u4f7f\u7528\u6b63\u5728\u589e\u52a0\u3002\u4e3a\u4e86\u7b26\u5408\u56fd\u9645\u4e13\u5229\u548c\u8d38\u6613\u534f\u8bae\uff0c\u8fd9\u4e9b\u4ea7\u54c1\u7684\u5f00\u53d1\u548c\u9500\u552e\u5fc5\u987b\u7b26\u5408\u56fd\u5bb6\u548c\u56fd\u9645\u6cd5\u5f8b\uff0c\u5e76\u4e14\u901a\u7528\u4ea7\u54c1\u5fc5\u987b\u8bc1\u660e\u5b83\u4eec\u5177\u6709\u76f8\u540c\u7684\u8d28\u91cf\u5e76\u4e14\u5728\u6cbb\u7597\u4e0a\u7b49\u540c\u4e8e\u54c1\u724c\u540d\u79f0\u66ff\u4ee3\u54c1\u3002\u4f46\u662f\uff0c\u8bb8\u591a\u56fd\u5bb6\u8d44\u6e90\u6709\u9650\uff0c\u65e0\u6cd5\u68c0\u67e5\u548c\u6838\u5b9e\u5176\u56fd\u5185\u9500\u552e\u7684\u6240\u6709\u836f\u54c1\u7684\u8d28\u91cf\u3002\u8be5\u6807\u9898\u8ba8\u8bba\u4e86\u901a\u7528\u548c\u591a\u6e90\u836f\u54c1\u6ce8\u518c\u7684\u5168\u7403\u7acb\u6cd5\u548c\u76d1\u7ba1\u8981\u6c42\u3002<\/span><\/p>\n


<\/span><\/strong><\/p>\n

\u7b2c\u4e03\u672c<\/span><\/strong>\uff1a<\/span><\/strong>\u5916\u7528\u836f\u7269\u7684\u751f\u7269\u5229\u7528\u5ea6\uff0c\u751f\u7269\u7b49\u6548\u6027\u548c\u6e17\u900f\u6027<\/span><\/strong><\/p>\n

 <\/span><\/strong><\/p>\n

\"BE\u7814\u7a76,\u63a8\u8350\u8bfb\u8bfb\u8fd9\u51e0\u672c\u4e66\"<\/p>\n

\u4f5c\u8005\uff08S\uff09\uff1a<\/span><\/strong>Vinod P. Shah\uff0cHoward I. Maibach<\/span>\uff0cJohn Jenner<\/span>\uff08\u7f16\u8f91\uff09<\/span><\/strong>
<\/p>\n

\u51fa\u7248\u5546\uff1a<\/span><\/strong>Springer-Verlag\u7ebd\u7ea6<\/span><\/strong><\/p>\n

 <\/span><\/p>\n

\u8be5\u6743\u5a01\u6027\u6587\u7ae0\u63a2\u8ba8\u4e86\u7528\u4e8e\u6d4b\u91cf\u836f\u7269\u548c\u5316\u5b66\u54c1\u7ecf\u76ae\u6e17\u900f\u7684\u6280\u672f\u7684\u8fdb\u5c55\uff0c\u4ee5\u8bc4\u4f30\u751f\u7269\u5229\u7528\u5ea6\u548c\u751f\u7269\u7b49\u6548\u6027\uff0c\u5e76\u8ba8\u8bba\u4e86\u5b83\u4eec\u5982\u4f55\u7528\u4e8e\u4e34\u5e8a\u548c\u79d1\u5b66\u7814\u7a76\u3002\u4e03\u4e2a\u7efc\u5408\u90e8\u5206\u7814\u7a76\u7684\u4e3b\u9898\u5305\u62ec\u4f53\u5916\u836f\u7269\u91ca\u653e\uff0c\u5c40\u90e8\u836f\u7269\u4ea7\u54c1\uff0c\u4e34\u5e8a\u7814\u7a76\uff0c\u6307\u5357\u548c\u7814\u8ba8\u4f1a\u62a5\u544a\u7b49\u3002\u8be5\u4e66\u8fd8\u63cf\u8ff0\u4e86\u9776\u5411\u900f\u76ae\u7ed9\u836f\u548c\u66f4\u590d\u6742\u7684\u6570\u5b66\u5efa\u6a21\u5982\u4f55\u6709\u52a9\u4e8e\u7406\u89e3\u900f\u76ae\u836f\u7269\u7684\u751f\u7269\u5229\u7528\u5ea6\u3002<\/span><\/p>\n

 <\/span><\/p>\n

\u672c\u4e66\u7684\u7b2c\u4e00\u7248\u662f\u7814\u7a76\u4eba\u5458\u786e\u5b9a\u7a7f\u900f\u76ae\u80a4\u7684\u836f\u7269\u548c\u5316\u5b66\u54c1\u7684\u6709\u6548\u6027\u548c\u5b89\u5168\u6027\u7684\u91cd\u8981\u53c2\u8003\u6307\u5357\u3002\u672c\u7b2c\u4e8c\u7248\u5305\u542b\u8be5\u9886\u57df\u7684\u5c16\u7aef\u8fdb\u5c55\uff0c\u5e76\u4e14\u662f\u5bfb\u6c42\u5b9a\u4e49\u7ecf\u76ae\u6d3b\u6027\u5316\u5408\u7269\u7684\u751f\u7269\u5229\u7528\u5ea6\u548c\u751f\u7269\u7b49\u6548\u6027\u4ee5\u6539\u5584\u79d1\u5b66\u548c\u4e34\u5e8a\u8c03\u67e5\u548c\u8c03\u63a7\u7684\u4eba\u5458\u7684\u5173\u952e\u8d44\u6e90\u3002<\/span><\/p>\n


<\/span><\/strong><\/span><\/p>\n

\u7b2c\u516b\u672c \u751f\u7269\u5229\u7528\u5ea6\u548c\u751f\u7269\u7b49\u6548\u6027\u7684\u8bbe\u8ba1\u548c\u5206\u6790<\/span><\/strong><\/span><\/p>\n


<\/span><\/strong><\/span><\/p>\n

\"BE\u7814\u7a76,\u63a8\u8350\u8bfb\u8bfb\u8fd9\u51e0\u672c\u4e66\"
<\/p>\n


<\/p>\n

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    \n
  • \n

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  • \n

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  • \n

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  • \n

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    <\/p>\n<\/ul>\n

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    <\/span><\/strong><\/p>\n

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    <\/p>\n

    \"BE\u7814\u7a76,\u63a8\u8350\u8bfb\u8bfb\u8fd9\u51e0\u672c\u4e66\"<\/p>\n

    \"BE\u7814\u7a76,\u63a8\u8350\u8bfb\u8bfb\u8fd9\u51e0\u672c\u4e66\"<\/p>\n


    <\/p>\n

    \u4e00\u81f4\u6027\u8bc4\u4ef7\u7684\u5173\u952e\u5728\u4e8e\u5236\u5242\u5f00\u53d1\u4e0a\u5360\u6709\u91cd\u8981\u7684\u56e0\u7d20\u3002\u505a\u597d\u5236\u5242\u624d\u662f\u8fc7BE\u7684\u5148\u51b3\u6761\u4ef6\u3002\u5e0c\u671b\u5404\u4f4d\u540c\u884c\u5173\u6ce8\u5236\u5242\u6280\u672f\u7684\u7814\u7a76\u3002\u6709\u673a\u4f1a\u7ed9\u5927\u5bb6\u63a8\u8350\u4e00\u4e9b\u5236\u5242\u7684\u539f\u7248\u4e66\u4f9b\u540c\u884c\u53c2\u8003\u3002<\/span>
    <\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section><\/div>\n","protected":false},"excerpt":{"rendered":"

    \u5916\u8d44\u5927\u578b\u5236\u836f\u516c\u53f8\u6280\u672f\u3001\u7814\u53d1\u3001\u8d28\u91cf\u603b\u76d1\uff0c\u9a8c\u8bc1\u7ba1\u7406\u8d44\u6df1\u4e13\u5bb6\uff0c\u591a\u5bb6\u5236\u836f\u516c\u53f8\u987e\u95ee\uff0c\u836f\u5b66\u7855\u58eb\u3002\u56fd\u5bb6\u5de5\u827a\u6838\u5bf9\u672a\u96e8\u7ef8\u7f2a\u4e4b\u9645\uff0c […]<\/p>\n","protected":false},"author":1,"featured_media":37527,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[2],"tags":[],"_links":{"self":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/37526"}],"collection":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/comments?post=37526"}],"version-history":[{"count":1,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/37526\/revisions"}],"predecessor-version":[{"id":37541,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/37526\/revisions\/37541"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/media\/37527"}],"wp:attachment":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/media?parent=37526"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/categories?post=37526"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/tags?post=37526"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}