{"id":38508,"date":"2018-08-22T01:00:00","date_gmt":"2018-09-17T06:21:37","guid":{"rendered":"http:\/\/www.05921.net\/index.php\/2018\/09\/17\/%e3%80%90%e8%bf%9b%e5%8f%a3%e6%96%b0%e8%8d%af%e8%b6%8b%e5%8a%bf%e3%80%91%e8%b7%a8%e5%9b%bd%e5%88%b6%e8%8d%af%e4%bc%81%e4%b8%9a%e8%bf%9b%e5%85%a5%e6%96%b0%e8%8d%af%e6%94%b6%e8%8e%b7%e5%af%86%e9%9b%86\/"},"modified":"2018-09-17T14:21:44","modified_gmt":"2018-09-17T06:21:44","slug":"%e3%80%90%e8%bf%9b%e5%8f%a3%e6%96%b0%e8%8d%af%e8%b6%8b%e5%8a%bf%e3%80%91%e8%b7%a8%e5%9b%bd%e5%88%b6%e8%8d%af%e4%bc%81%e4%b8%9a%e8%bf%9b%e5%85%a5%e6%96%b0%e8%8d%af%e6%94%b6%e8%8e%b7%e5%af%86%e9%9b%86","status":"publish","type":"post","link":"https:\/\/www.05921.net\/index.php\/38508\/","title":{"rendered":"\u3010\u8fdb\u53e3\u65b0\u836f\u8d8b\u52bf\u3011\u8de8\u56fd\u5236\u836f\u4f01\u4e1a\u8fdb\u5165\u65b0\u836f\u6536\u83b7\u5bc6\u96c6\u671f*"},"content":{"rendered":"
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Research\u533b\u836f\u4ebaDaniel\u5206\u4eab\u3002
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\u5fb7\u62c9\u9a6c\u5c3c\u7247<\/span><\/strong>\uff0c<\/span>Delamanid Tablets<\/span>\u3002<\/span><\/p>\n


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2018\u5e743\u670812\u65e5\uff0c\u6297\u7ed3\u6838\u65b0\u836f\u5fb7\u62c9\u9a6c\u5c3c\u7247\u6b63\u5f0f\u83b7\u5f97\u56fd\u5bb6\u98df\u54c1\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u603b\u5c40\u7684\u4e0a\u5e02\u6279\u51c6\u3002<\/span>\u7528\u4e8e\u5728\u56e0\u8010\u836f\u6216\u8010\u53d7\u6027\u539f\u56e0\u800c\u65e0\u6cd5\u7ec4\u6210\u6709\u6548\u6cbb\u7597\u65b9\u6848\u7684\u6307\u5f81\u4e0b\uff0c\u672c\u54c1\u53ef\u4f5c\u4e3a\u8054\u5408\u6cbb\u7597\u65b9\u6848\u7684\u4e00\u90e8\u5206\uff0c\u7528\u4e8e<\/span>\u6210\u4eba\u8010\u591a\u836f\u80ba\u7ed3\u6838\uff08MDR-TB\uff09<\/span><\/strong>\u60a3\u8005\u7684\u6cbb\u7597\u3002<\/span><\/p>\n


<\/p>\n

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\"\u3010\u8fdb\u53e3\u65b0\u836f\u8d8b\u52bf\u3011\u8de8\u56fd\u5236\u836f\u4f01\u4e1a\u8fdb\u5165\u65b0\u836f\u6536\u83b7\u5bc6\u96c6\u671f*\"<\/p>\n<\/section>\n

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\"\u3010\u8fdb\u53e3\u65b0\u836f\u8d8b\u52bf\u3011\u8de8\u56fd\u5236\u836f\u4f01\u4e1a\u8fdb\u5165\u65b0\u836f\u6536\u83b7\u5bc6\u96c6\u671f*\"<\/span><\/p>\n<\/section>\n

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2018\u5e748\u6708\uff0c\u56fd\u5bb6\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40\u6b63\u5f0f\u6279\u51c6\u4e86\u65b0\u4e00\u4ee3 <\/span>ALK \u6291\u5236\u5242<\/span><\/strong>\u5b89\u5723\u838e<\/span>\u00ae<\/span>\uff08\u5316\u5b66\u901a\u7528\u540d\uff0c<\/span>\u963f\u6765\u66ff\u5c3c<\/span><\/strong>\uff09\u8fdb\u53e3\u6ce8\u518c\u7533\u8bf7\uff0c\u7528\u4e8e\u6cbb\u7597\u95f4\u53d8\u6027\u6dcb\u5df4\u7624\u6fc0\u9176\uff08Anaplastic Lymphoma Kinase\uff0c\u7b80\u79f0 ALK\uff09\u9633\u6027\u7684\u5c40\u90e8\u665a\u671f\u6216\u8f6c\u79fb\u6027\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u3002<\/span><\/p>\n


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\"\u3010\u8fdb\u53e3\u65b0\u836f\u8d8b\u52bf\u3011\u8de8\u56fd\u5236\u836f\u4f01\u4e1a\u8fdb\u5165\u65b0\u836f\u6536\u83b7\u5bc6\u96c6\u671f*\"<\/p>\n


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\u9ed8\u6c99\u4e1c\u5ba3\u5e03\uff0c\u5176PD-1\u6291\u5236\u5242\u836f\u7269<\/span>\u5e15\u535a\u5229\u73e0\u5355\u6297\uff08Pembrolizumab\uff09<\/span><\/strong>\u6b63\u5f0f\u83b7\u5f97\u4e2d\u56fd\u56fd\u5bb6\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40\u5ba1\u6279\uff0c\u7528\u4e8e<\/span>\u7ecf\u4e00\u7ebf\u6cbb\u7597\u5931\u8d25\u7684\u4e0d\u53ef\u5207\u9664\u6216\u8f6c\u79fb\u6027\u9ed1\u8272\u7d20\u7624\u7684\u6cbb\u7597<\/span><\/strong>\u3002<\/span><\/p>\n


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\u6162\u6027\u4e19\u578b\u809d\u708e\u53e3\u670d\u76f4\u63a5\u6297\u75c5\u6bd2\u836f\u7269<\/span>\u62e9\u5fc5\u8fbe\uff08\u827e\u5c14\u5df4\u97e6\u683c\u62c9\u745e\u97e6\u7247\uff09<\/span><\/strong>\u5df2\u4e8e2018\u5e744\u670828\u65e5\u83b7\u5f97\u56fd\u5bb6\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40\uff08\u539f\u56fd\u5bb6\u98df\u54c1\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u603b\u5c40\uff09\u7684\u4e0a\u5e02\u6279\u51c6\uff0c\u9002\u7528\u4e8e\u6cbb\u7597\u57fa\u56e0 1\u30014 \u578b\u6162\u6027\u4e19\u809d\u7684\u6210\u5e74\u60a3\u8005\u3002<\/span><\/p>\n


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\"\u3010\u8fdb\u53e3\u65b0\u836f\u8d8b\u52bf\u3011\u8de8\u56fd\u5236\u836f\u4f01\u4e1a\u8fdb\u5165\u65b0\u836f\u6536\u83b7\u5bc6\u96c6\u671f*\"<\/p>\n<\/section>\n

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\n

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2018\u5e748\u67086\u65e5\uff0c\u8f89\u745e\u5ba3\u5e03\uff0c\u5168\u7403\u9996\u4e2a\u7ec6\u80de\u5468\u671f\u86cb\u767d\u4f9d\u8d56\u6027\u6fc0\u9176\uff08CDK\uff094\/6\u6291\u5236\u5242<\/span>\u7231\u535a\u65b0\u00ae IBRANCE\u00ae\uff08\u54cc\u67cf\u897f\u5229, palbociclib\uff09<\/span><\/strong>\u5df2\u4e8e7\u670831\u65e5\u83b7\u5f97\u4e2d\u56fd\u56fd\u5bb6\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40\u6279\u51c6\u3002\u7231\u535a\u65b0\u00ae\u9002\u7528\u4e8e<\/span>\u6cbb\u7597\u6fc0\u7d20\u53d7\u4f53\uff08HR\uff09\u9633\u6027\u3001\u4eba\u8868\u76ae\u751f\u957f\u56e0\u5b50\u53d7\u4f53 2\uff08HER2\uff09\u9634\u6027\u7684\u5c40\u90e8\u665a\u671f\u6216\u8f6c\u79fb\u6027\u4e73\u817a\u764c<\/span><\/strong>\uff0c\u5e94\u4e0e\u82b3\u9999\u5316\u9176\u6291\u5236\u5242\u8054\u5408\u4f7f\u7528\u4f5c\u4e3a\u7edd\u7ecf\u540e\u5973\u6027\u60a3\u8005\u7684\u521d\u59cb\u5185\u5206\u6ccc\u6cbb\u7597\u3002<\/span><\/p>\n


<\/p>\n<\/section>\n

\n

\"\u3010\u8fdb\u53e3\u65b0\u836f\u8d8b\u52bf\u3011\u8de8\u56fd\u5236\u836f\u4f01\u4e1a\u8fdb\u5165\u65b0\u836f\u6536\u83b7\u5bc6\u96c6\u671f*\"<\/p>\n<\/section>\n

\n


<\/p>\n<\/section>\n

\n
\n
\n
\n
\n
\n
\n
<\/section>\n<\/section>\n
\n
<\/section>\n<\/section>\n<\/section>\n<\/section>\n
<\/section>\n
\n
\u8bfa\u534e<\/strong><\/span><\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n
\n


<\/p>\n<\/section>\n

\n

2018\u5e745\u670831\u65e5\uff0c\u56fd\u5bb6\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40\u6279\u51c6\u9996\u4e2a\u7528\u4e8e\u6cbb\u7597\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\uff08NSCLC\uff09\u4e2d\u7684\u95f4\u53d8\u6027\u6dcb\u5df4\u7624\u6fc0\u9176<\/span>\uff08ALK\uff09<\/span>\u9633\u6027\u60a3\u8005\u7684\u4e8c\u4ee3\u5c0f\u5206\u5b50\u53e3\u670d\u9776\u5411\u6cbb\u7597\u836f\u7269\uff0c\u5373ALK\u6291\u5236\u5242<\/span>\u585e\u745e\u66ff\u5c3c\u80f6\u56ca<\/span>\uff08\u5546\u54c1\u540d\u8d5e\u53ef\u8fbe\u00ae\uff09\u3002<\/span> <\/span><\/p>\n


<\/p>\n

\"\u3010\u8fdb\u53e3\u65b0\u836f\u8d8b\u52bf\u3011\u8de8\u56fd\u5236\u836f\u4f01\u4e1a\u8fdb\u5165\u65b0\u836f\u6536\u83b7\u5bc6\u96c6\u671f*\"<\/p>\n<\/section>\n

\n


<\/p>\n

\u8fd1\u51e0\u5341\u5e74\u80ba\u764c\u5df2\u6210\u4e3a\u4e16\u754c\u4e0a\u6700\u5e38\u89c1\u7684\u764c\u75c7\u3002\u80ba\u764c\u4eba\u7fa4\u4e2d\u7684\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\uff08NSCLC\uff09\u7ea6\u5360\u6240\u6709\u80ba\u764c\u75c5\u4f8b\u768485%\u4ee5\u4e0a\u3002\u95f4\u53d8\u6027\u6dcb\u5df4\u7624\u6fc0\u9176\uff08ALK\uff09\u9633\u6027\u7684NSCLC\u4e0e\u4e00\u822c\u7684NSCLC\u4eba\u7fa4\u76f8\u6bd4\uff0c\u503e\u5411\u4e8e\u66f4\u52a0\u5e74\u8f7b\u3001\u901a\u5e38\u8868\u73b0\u4e3a\u817a\u764c\u7ec4\u7ec7\u5b66\u7c7b\u578b\u3001\u975e\u5438\u70df\u8005\uff0c\u4e14\u4e0eEGFR\u53caKRAS\u7a81\u53d8\u4e92\u65a5\uff0c\u8fd9\u4e0eALK\u91cd\u6392\u5b9a\u4e49\u4e86\u4e00\u79cd\u72ec\u7279\u7684NSCLC\u5206\u5b50\u4e9a\u7fa4\u7684\u6982\u5ff5\u76f8\u543b\u5408\u3002\u5728\u5168\u7403NSCLC\u60a3\u8005\u4e2d\u7ea6\u67092%-7%\u53ef\u68c0\u6d4b\u5230ALK\u91cd\u6392\u3002\u901a\u8fc7\u5bf9\u4e8e\u4e2d\u56fd\u7684ALK\u9633\u6027NSCLC\u6d41\u884c\u75c5\u5b66\u5206\u6790\u53ca\u6587\u732e\u68c0\u7d22\uff0c\u4e2d\u56fdALK\u9633\u6027NSCLC\u6d41\u884c\u75c5\u5b66\u7279\u5f81\u4e0e\u56fd\u9645\u6570\u636e\u57fa\u672c\u76f8\u4f3c\u3002<\/span><\/p>\n


<\/p>\n

2018\u5e747\u670821\u65e5\uff0c\u8bfa\u534e\u80bf\u7624\uff08\u4e2d\u56fd\uff09\u5ba3\u5e03\uff0c\u9996\u4e2a\u4e5f\u662f\u552f\u4e00\u83b7\u6279\u7684<\/span>\u975e\u80bd\u7c7b\u53e3\u670d\u8840\u5c0f\u677f\u751f\u6210\u7d20\u53d7\u4f53\u6fc0\u52a8\u5242\uff08TPO-RA\uff09\u745e\u5f17\u5170\u00ae\uff08\u901a\u7528\u540d\uff1a\u827e\u66f2\u6cca\u5e15\u4e59\u9187\u80fa\u7247\uff09<\/span><\/strong>\u6b63\u5f0f\u5728\u4e2d\u56fd\u4e0a\u5e02\uff0c\u5c06\u7528\u4e8e\u6cbb\u7597\u7ecf\u7cd6\u76ae\u8d28\u6fc0\u7d20\u7c7b\u836f\u7269\u3001\u514d\u75ab\u7403\u86cb\u767d\u6cbb\u7597\u65e0\u6548\u6216\u813e\u5207\u9664\u672f\u540e\u6162\u6027\u539f\u53d1\u514d\u75ab\u6027\u8840\u5c0f\u677f\u51cf\u5c11\u75c7\uff08ITP\uff09\u60a3\u8005\u7684\u8840\u5c0f\u677f\u51cf\u5c11\u3002 <\/span><\/p>\n

\u8bfa\u534e\u5236\u836f\uff08\u4e2d\u56fd\uff09\u4e8e2018\u5e745\u6708\u5ba3\u5e03\uff0c<\/span>\u8bfa\u9002\u5f97\u00ae\uff08\u96f7\u73e0\u5355\u6297\uff09<\/span><\/strong>\u83b7\u56fd\u5bb6\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40\u6279\u51c6\u7528\u4e8e\u6cbb\u7597\u7ee7\u53d1\u4e8e\u89c6\u7f51\u819c\u9759\u8109\u963b\u585e\uff08RVO\uff09\uff0c\u5305\u62ec\u89c6\u7f51\u819c\u5206\u652f\u9759\u8109\u963b\u585e\uff08BRVO\uff09\u6216\u89c6\u7f51\u819c\u4e2d\u592e\u9759\u8109\u963b\u585e\uff08CRVO\uff09\u7684\u9ec4\u6591\u6c34\u80bf\u5f15\u8d77\u7684\u89c6\u529b\u635f\u5bb3\uff0c\u6210\u4e3a<\/span>\u4e2d\u56fd\u76ee\u524d\u552f\u4e00\u5177\u6709\u89c6\u7f51\u819c\u9759\u8109\u963b\u585e\u9002\u5e94\u75c7\u7684\u6297VEGF\u836f\u7269<\/span><\/strong>\u3002<\/span><\/p>\n


<\/p>\n

\u89c6\u7f51\u819c\u9759\u8109\u963b\u585e\u662f\u7531\u4e8e\u89c6\u7f51\u819c\u9759\u8109\u8840\u6813\u5f62\u6210\u800c\u9020\u6210\u7684\uff0c\u662f\u7b2c\u4e8c\u5e38\u89c1\u7684\u89c6\u7f51\u819c\u8840\u7ba1\u6027\u75be\u75c5\u3002RVO\u5728\u4e16\u754c\u8303\u56f4\u5185\u5f71\u54cd\u7ea61600\u4e07\u4eba\uff0c\u56e0RVO\u7ee7\u53d1\u7684\u9ec4\u6591\u6c34\u80bf\uff08ME\uff09\u662f\u9020\u6210\u60a3\u8005\u89c6\u529b\u635f\u4f24\u7684\u4e3b\u8981\u539f\u56e0\uff0c\u60a3\u8005\u53ef\u80fd\u51fa\u73b0\u89c6\u7269\u6a21\u7cca\uff0c\u7a81\u7136\u65e0\u75db\u7684\u89c6\u529b\u4e27\u5931\u6216\u89c6\u7269\u53d8\u5f62\u7b49\u75c7\u72b6\u3002<\/span><\/p>\n


<\/p>\n

\u683c\u9686\u6eb4\u94f5\u5438\u5165\u7c89\u96fe\u5242\u7528\u80f6\u56ca<\/span><\/strong>\uff0c2018\u5e744\u670816\u65e5\uff0c\u83b7\u6279\u4e0a\u5e02\u3002<\/span><\/p>\n

\u683c\u9686\u6eb4\u94f5\u5438\u5165\u7c89\u96fe\u5242\u662f\u4e00\u79cd\u5438\u5165\u7528\u957f\u6548\u6bd2\u8548\u78b1\u53d7\u4f53\u62ee\u6297\u5242(\u6297\u80c6\u78b1\u80fd\u836f\u7269)\uff0c\u7528\u4e8e\u7f13\u89e3\u6162\u6027\u963b\u585e\u6027\u80ba\u75be\u75c5(COPD)\u6210\u5e74\u60a3\u8005\u7684\u75c7\u72b6\u3002<\/span><\/p>\n

\u8bfa\u534e<\/span>\u683c\u9686\u6eb4\u94f5\u5438\u5165\u7c89\u96fe\u5242\uff08Seebri Breezhaler\uff09<\/span>\uff0c<\/span>2016\u5e74\u5168\u7403\u9500\u552e\u989d\u7ea6\u4e3a1.57\u4ebf\u7f8e\u5143\u3002<\/span><\/p>\n


<\/p>\n<\/section>\n

\n

\"\u3010\u8fdb\u53e3\u65b0\u836f\u8d8b\u52bf\u3011\u8de8\u56fd\u5236\u836f\u4f01\u4e1a\u8fdb\u5165\u65b0\u836f\u6536\u83b7\u5bc6\u96c6\u671f*\"<\/p>\n


<\/p>\n<\/section>\n

\n
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<\/section>\n<\/section>\n
\n
<\/section>\n<\/section>\n<\/section>\n<\/section>\n
<\/section>\n
\n
\u52c3\u6797\u683c\u6bb7\u683c\u7ff0<\/strong><\/span><\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n
\n


<\/p>\n<\/section>\n

\n

2018\u5e747\u670827\u65e5\uff0c\u52c3\u6797\u683c\u6bb7\u683c\u7ff0\u5ba3\u5e03\uff0c<\/span>\u601d\u5408\u534e\u80fd\u500d\u4e50\uff08\u567b\u6258\u6eb4\u94f5\/\u5965\u8fbe\u7279\u7f57\u5438\u5165\u55b7\u96fe\u5242\uff09<\/span><\/strong>\u83b7\u5f97\u4e2d\u56fd\u98df\u54c1\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40\u6b63\u5f0f\u6279\u51c6\uff0c\u7528\u4e8e\u6162\u6027\u963b\u585e\u6027\u80ba\u75be\u75c5\uff08\u5305\u62ec\u6162\u6027\u652f\u6c14\u7ba1\u708e\u548c\u80ba\u6c14\u80bf\uff09\u60a3\u8005\u7684\u957f\u671f\u7ef4\u6301\u6cbb\u7597\u3002<\/span><\/p>\n


<\/p>\n

\"\u3010\u8fdb\u53e3\u65b0\u836f\u8d8b\u52bf\u3011\u8de8\u56fd\u5236\u836f\u4f01\u4e1a\u8fdb\u5165\u65b0\u836f\u6536\u83b7\u5bc6\u96c6\u671f*\"<\/p>\n<\/section>\n

\n


<\/p>\n<\/section>\n

\n

\u567b\u6258\u6eb4\u94f5\/\u5965\u8fbe\u7279\u7f57\u5438\u5165\u55b7\u96fe\u5242\u4e5f\u662f\u76ee\u524d\u6162\u963b\u80ba\u6cbb\u7597\u9886\u57df\u552f\u4e00\u542b\u6709\u567b\u6258\u6eb4\u94f5\u3001\u4e14\u552f\u4e00\u7ecf\u7531\u72ec\u521b\u8f6f\u96fe\u5438\u5165\u88c5\u7f6e\u9012\u9001\u7684\u53cc\u652f\u6c14\u7ba1\u6269\u5f20\u5242\uff08\u53cc\u652f\u6269\u5242\uff09\u3002\u5728\u4e2d\u56fd\uff0c \u5176\u83b7\u6279\u6210\u4eba\u63a8\u8350\u5242\u91cf\u4e3a\u567b\u6258\u6eb4\u94f55\u03bcg\/\u5965\u8fbe\u7279\u7f575\u03bcg\uff0c\u6bcf\u65e5\u4e00\u6b21\u3002<\/span><\/p>\n


<\/p>\n

\u6cf0\u6bd5\u5168\u00ae \uff08\u8fbe\u6bd4\u52a0\u7fa4\u916f\uff09 \u7684\u7279\u5f02\u6027\u9006\u8f6c\u5242\u6cf0\u6bd5\u5b89\u00ae \uff08\u4f9d\u8fbe\u8d5b\u73e0\u5355\u6297\uff09<\/span><\/strong>\u5df2\u83b7\u5f97\u56fd\u5bb6\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40\u6279\u51c6\u3002\u8fbe\u6bd4\u52a0\u7fa4\u916f\u6210\u4e3a\u76ee\u524d\u56fd\u5185\u552f\u4e00\u4e00\u4e2a\u62e5\u6709\u83b7\u6279\u7684\u7279\u5f02\u6027\u9006\u8f6c\u5242\u7684\u975e\u7ef4\u751f\u7d20K\u62ee\u6297\u7c7b\u53e3\u670d\u6297\u51dd\u836f\u3002\u4f9d\u8fbe\u8d5b\u73e0\u5355\u6297\u83b7\u6279\u7528\u4e8e\u63a5\u53d7\u8fbe\u6bd4\u52a0\u7fa4\u916f\u6cbb\u7597\u7684\u60a3\u8005\uff0c\u5728\u6025\u8bca\u5916\u79d1\u624b\u672f\/\u7d27\u6025\u64cd\u4f5c\u6216\u8005\u51fa\u73b0\u5371\u53ca\u751f\u547d\/\u65e0\u6cd5\u63a7\u5236\u7684\u51fa\u8840\uff0c\u9700\u8981\u8fc5\u901f\u9006\u8f6c\u8fbe\u6bd4\u52a0\u7fa4\u916f\u7684\u6297\u51dd\u6548\u5e94\u65f6\u4f7f\u7528\u3002<\/span><\/p>\n


<\/p>\n<\/section>\n

\n

\"\u3010\u8fdb\u53e3\u65b0\u836f\u8d8b\u52bf\u3011\u8de8\u56fd\u5236\u836f\u4f01\u4e1a\u8fdb\u5165\u65b0\u836f\u6536\u83b7\u5bc6\u96c6\u671f*\"<\/p>\n<\/section>\n

\n


<\/p>\n<\/section>\n

\n
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<\/section>\n<\/section>\n
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<\/section>\n<\/section>\n<\/section>\n<\/section>\n
<\/section>\n
\n
\u827e\u4f2f\u7ef4<\/strong><\/span><\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n
\n


<\/p>\n<\/section>\n

\n

2018\u5e743\u670820\u65e5\uff0c\u827e\u4f2f\u7ef4\u5ba3\u5e03\uff0c<\/span>\u7ef4\u5efa\u4e50\u00ae\uff08\u5965\u6bd4\u5e15\u5229\u7247\uff09\u8054\u5408\u6613\u5947\u745e\u00ae\uff08\u8fbe\u585e\u5e03\u97e6\u94a0\u7247\uff09\u4e19\u809d\u6cbb\u7597\u65b9\u6848<\/span><\/strong>\u5df2\u83b7\u5f97\u4e2d\u56fd\u56fd\u5bb6\u98df\u54c1\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u603b\u5c40\uff08CFDA\uff09\u6279\u51c6\uff0c\u6cbb\u7597\u57fa\u56e01b\u578b\u3001\u521d\u6cbb\u3001\u8f7b\u5ea6\u81f3\u4e2d\u5ea6\u809d\u7ea4\u7ef4\u5316\uff08F0-F2\uff09\u6162\u6027\u4e19\u578b\u809d\u708e\u60a3\u8005\uff0c\u7597\u7a0b\u53ef\u7f29\u77ed\u81f38\u5468\uff0c\u662f\u4e2d\u56fd\u9996\u4e2a\u83b7\u6279\u76848\u5468\u6cbb\u7597\u65b9\u6848\u3002\u6b64\u65b9\u6848\u4e3a\u5168\u53e3\u670d\uff0c\u65e0\u5e72\u6270\u7d20\uff0c\u5305\u542b3\u79cd\u76f4\u63a5\u6297\u75c5\u6bd2\u836f\u7269\uff0c\u53ef\u9488\u5bf9\u4e19\u809d\u75c5\u6bd2\u751f\u547d\u5468\u671f\u76843\u4e2a\u4e3b\u8981\u9776\u70b9\uff0c\u6291\u5236\u4e19\u809d\u75c5\u6bd2\u7684\u590d\u5236\u3002<\/span><\/p>\n


<\/p>\n<\/section>\n

\n
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<\/section>\n<\/section>\n
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<\/section>\n<\/section>\n<\/section>\n<\/section>\n
<\/section>\n
\n
\u8d5b\u8bfa\u83f2<\/strong><\/span><\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n
\n


<\/p>\n<\/section>\n

\n

\u65e5\u524d\uff0c\u56fd\u5bb6\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40\u5df2\u6279\u51c6<\/span>\u5965\u5df4\u6377(\u7279\u7acb\u6c1f\u80fa\u7247)<\/span><\/strong>\u5728\u4e2d\u56fd\u4e0a\u5e02\uff0c\u7528\u4e8e\u6cbb\u7597\u590d\u53d1\u578b\u591a\u53d1\u6027\u786c\u5316\uff0c\u8fd9\u4e5f\u662f\u76ee\u524d\u5728\u4e2d\u56fd\u83b7\u6279\u7684\u6cbb\u7597\u591a\u53d1\u6027\u786c\u5316\u7684\u53e3\u670d\u578b\u6cbb\u7597\u836f\u7269\u3002<\/span><\/p>\n


<\/p>\n<\/section>\n

\n

\"\u3010\u8fdb\u53e3\u65b0\u836f\u8d8b\u52bf\u3011\u8de8\u56fd\u5236\u836f\u4f01\u4e1a\u8fdb\u5165\u65b0\u836f\u6536\u83b7\u5bc6\u96c6\u671f*\"<\/p>\n<\/section>\n

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\u65e5\u672c\u82cf\u7231\u5eb7<\/strong><\/span><\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n
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2018\u5e747\u6708\uff0c<\/span>\u65e5\u672c\u82cf\u7231\u5eb7\u6b63\u5f0f\u5ba3\u5e03<\/span>\u5584\u53ef\u8212\u00ae\uff08\u683c\u62c9\u53f8\u743c\u900f\u76ae\u8d34\u7247\uff09<\/span><\/strong>\u5df2\u83b7\u5f97\u4e2d\u56fd\u56fd\u5bb6\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40\uff08CNDA\uff09\u7684\u4e0a\u5e02\u6279\u51c6\u3002\u5584\u53ef\u8212\u00ae\u662f\u5168\u7403\u9996\u4e2a\u4e14\u552f\u4e00\u4e00\u4e2a5-HT3\u53d7\u4f53\u62ee\u6297\u5242\u7684\u900f\u76ae\u8d34\u7247\u4ea7\u54c1\uff0c\u7528\u4e8e\u9884\u9632\u4e2d\u5ea6\u548c\/\u6216\u9ad8\u5ea6\u81f4\u5410\u6027\u5316\u7597\u5f15\u8d77\u7684\u6076\u5fc3\u548c\u5455\u5410\uff0c\u4e3a\u5316\u7597\u60a3\u8005\u7684\u6076\u5fc3\u5455\u5410\u9884\u9632\u63d0\u4f9b\u4e86\u4e00\u79cd\u7597\u6548\u6301\u4e45\u7a33\u5b9a\u3001\u65e0\u521b\u7684\u7ed9\u836f\u65b0\u9014\u5f84\u3002ProStrakan, Inc.<\/span><\/p>\n


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\n

2018\u5e747\u6708\uff0c<\/span><\/strong> \u5f3a\u751f-\u897f\u5b89\u6768\u68ee\u5236\u836f\u5ba3\u5e03\uff0c\u56fd\u5bb6\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40\u5df2\u6b63\u5f0f\u6279\u51c6<\/span>\u666e\u6cfd\u529b\u00ae\uff08\u8fbe\u82a6\u90a3\u97e6\u8003\u6bd4\u53f8\u4ed6\u7247\uff09<\/span><\/strong>\u4e0e\u5176\u4ed6\u6297\u9006\u8f6c\u5f55\u75c5\u6bd2\u836f\u7269\u8054\u5408\u4f7f\u7528\u6cbb\u7597\u4eba\u7c7b\u514d\u75ab\u7f3a\u9677\u75c5\u6bd2\uff08HIV\uff09\u611f\u67d3\u6210\u5e74\u60a3\u8005\uff0c\u5176\u4e2d\u5305\u62ec\uff1a\u6297\u9006\u8f6c\u5f55\u75c5\u6bd2\u836f\u7269\u521d\u6cbb\u6210\u5e74\u60a3\u8005\uff0c\u4ee5\u53ca\u672a\u51fa\u73b0\u8fbe\u82a6\u90a3\u97e6\u8010\u836f\u76f8\u5173\u7a81\u53d8\u7684\u65e2\u5f80\u63a5\u53d7\u6297\u9006\u8f6c\u5f55\u75c5\u6bd2\u836f\u7269\u6cbb\u7597\u7684\u6210\u5e74\u60a3\u8005\u3002<\/span><\/p>\n


<\/p>\n

\u897f\u5b89\u6768\u68ee\u5ba3\u5e03<\/span>\u4ebf\u73c2\u00ae\uff08\u4f0a\u5e03\u66ff\u5c3c\u80f6\u56ca\uff09<\/span><\/strong>\u83b7\u56fd\u5bb6\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40\u201c\u4f18\u5148\u5ba1\u8bc4\u201d\u8d44\u683c\u83b7\u6279\u6210\u4e3a<\/span>\u56fd\u5185\u9996\u4e2a\u6162\u6027\u6dcb\u5df4\u7ec6\u80de\u767d\u8840\u75c5\/\u5c0f\u6dcb\u5df4\u7ec6\u80de\u6dcb\u5df4\u7624\u4e00\u7ebf\u6cbb\u7597<\/span><\/strong>\u7684\u53e3\u670d\u9776\u5411\u7597\u6cd5\u3002<\/span><\/p>\n


<\/p>\n

\u56fd\u5bb6\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40\u6b63\u5f0f\u6279\u51c6<\/span>\u6cbb\u7597\u7cbe\u795e\u5206\u88c2\u75c7\u957f\u6548\u9488\u5242 \u5584\u59a5\u8fbe\u00ae<\/span><\/strong>\u68d5\u6988\u5e15\u5229\u54cc\u916e\u916f\u6ce8\u5c04\u6db2\uff083\u4e2a\u6708\u5242\u578b\uff0c3M\uff09<\/span><\/strong>\u5728\u4e2d\u56fd\u4e0a\u5e02\u3002<\/span><\/p>\n


<\/p>\n<\/section>\n

\n

\"\u3010\u8fdb\u53e3\u65b0\u836f\u8d8b\u52bf\u3011\u8de8\u56fd\u5236\u836f\u4f01\u4e1a\u8fdb\u5165\u65b0\u836f\u6536\u83b7\u5bc6\u96c6\u671f*\"<\/p>\n<\/section>\n

\n


<\/p>\n

2018\u5e741\u67084\u65e5,\u897f\u5b89\u6768\u68ee\u5236\u5ba3\u5e03\uff0c \u56fd\u5bb6\u98df\u54c1\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u603b\u5c40\u5df2\u7ecf\u6279\u51c6<\/span>\u6b23\u666e\u5c3c\u00ae(SIMPONI\u00ae)\uff0c\u6208\u5229\u6728\u5355\u6297\u6ce8\u5c04\u6db2<\/span><\/strong>\uff0c\u7528\u4e8e\u6cbb\u7597\u6d3b\u52a8\u6027\u5f3a\u76f4\u6027\u810a\u67f1\u708e\u6210\u5e74\u60a3\u8005\uff1b\u4e5f\u53ef\u8054\u5408\u7532\u6c28\u8776\u5464\uff08MTX\uff09\u6cbb\u7597\u5bf9MTX\u5728\u5185\u7684\u6539\u5584\u75c5\u60c5\u6297\u98ce\u6e7f\u836f\u7269\u7597\u6548\u4e0d\u4f73\u7684\u4e2d\u5230\u91cd\u5ea6\u6d3b\u52a8\u6027\u7c7b\u98ce\u6e7f\u5173\u8282\u708e\u6210\u5e74\u60a3\u8005\u3002<\/span><\/p>\n


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\u767e\u65f6\u7f8e\u65bd\u8d35\u5b9d<\/strong><\/span><\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n
\n


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\n

2018\u5e746\u670815\u65e5\uff0c<\/span>\u7eb3\u6b66\u5229\u5c24\u5355\u6297\u6ce8\u5c04\u6db2\uff08\u82f1\u6587\u540d\uff1aNivolumab Injection\uff09<\/span><\/strong>\u5728\u4e2d\u56fd\u7684\u4e0a\u5e02\u7533\u8bf7\u6b63\u5f0f\u83b7\u5f97\u56fd\u5bb6\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40\uff08CFDA\uff09\u6279\u51c6\u3002<\/span><\/p>\n


<\/p>\n

\"\u3010\u8fdb\u53e3\u65b0\u836f\u8d8b\u52bf\u3011\u8de8\u56fd\u5236\u836f\u4f01\u4e1a\u8fdb\u5165\u65b0\u836f\u6536\u83b7\u5bc6\u96c6\u671f*\"<\/p>\n<\/section>\n

\n


<\/p>\n

\u6b64\u6b21\u6211\u56fd\u6279\u51c6\u7684\u9002\u5e94\u8bc1\u4e3a\uff1a<\/span><\/strong><\/span><\/p>\n

\u7528\u4e8e\u6cbb\u7597\u8868\u76ae\u751f\u957f\u56e0\u5b50\u53d7\u4f53\uff08<\/span>EGFR\uff09\u57fa\u56e0\u7a81\u53d8\u9634\u6027\u548c\u95f4\u53d8\u6027\u6dcb\u5df4\u7624\u6fc0\u9176\uff08ALK\uff09\u9634\u6027\u3001\u65e2\u5f80\u63a5\u53d7\u8fc7\u542b\u94c2\u65b9\u6848\u5316\u7597\u540e\u75be\u75c5\u8fdb\u5c55\u6216\u4e0d\u53ef\u8010\u53d7\u7684\u5c40\u90e8\u665a\u671f\u6216\u8f6c\u79fb\u6027\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\uff08NSCLC\uff09\u6210\u4eba\u60a3\u8005\u3002<\/span><\/p>\n


<\/p>\n

\u636e\u53ef\u9760\u6d88\u606f\uff0c\u6b63\u5f0f\u5f00\u59cb\u9500\u552e\u7684\u65f6\u95f4\u9884\u8ba1\u662f<\/span>8\u6708\u4e0b\u65ec\uff0c\u4e0d\u4f1a\u518d\u63a8\u8fdf\u52309\u6708\u3002
\u6bcf\u4e2a\u6708\u7684\u7528\u836f\u6210\u672c\u5728<\/span>4\u4e07\u5143\u5de6\u53f3\u3002 \u5177\u4f53\u4ee5\u5b9e\u9645\u516c\u5e03\u4ef7\u683c\u4e3a\u51c6\u3002\u636e\u4e86\u89e3\uff0c\u4e2d\u534e\u6148\u5584\u603b\u4f1aO\u836f\u7684\u6148\u5584\u8d60\u836f\uff0c\u6709\u4f20\u95fb\u662f\u4e705\u4e2a\u6708\u90017\u4e2a\u6708\uff0c\u5177\u4f53\u9700\u8981\u5173\u6ce8\u4e2d\u534e\u6148\u5584\u603b\u4f1a\u53d1\u5e03\u7684\u5b98\u65b9\u4fe1\u606f\u3002\u56fd\u4ea7PD-1\u5355\u6297\u9884\u8ba1\u8d60\u836f\u540e10-12\u4e07?<\/span><\/p>\n


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\n

2018\u5e742\u670813\u65e5\uff0c\u62dc\u8033\u5e03\uff0c\u56fd\u5bb6\u98df\u54c1\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u603b\u5c40\uff08CFDA\uff09\u5df2\u6279\u51c6<\/span>\u827e\u529b\u96c5\u00ae\uff08\u963f\u67cf\u897f\u666e\u773c\u5185\u6ce8\u5c04\u6eb6\u6db2\uff09<\/span><\/strong>\u7528\u4e8e\u6cbb\u7597\u6210\u4eba\u7cd6\u5c3f\u75c5\u6027\u9ec4\u6591\u6c34\u80bf\uff08DME\uff09\u3002\u8be5\u836f\u7269\u7684\u4e0a\u5e02\u7533\u8bf7\u66fe\u88ab\u7eb3\u5165\u4f18\u5148\u5ba1\u8bc4\u7a0b\u5e8f\u3002<\/span>\u827e\u529b\u96c5\u00ae\u662f\u4e2d\u56fd\u76ee\u524d\u552f\u4e00\u83b7\u51c6\u7528\u4e8e\u6cbb\u7597\u7cd6\u5c3f\u75c5\u6027\u9ec4\u6591\u6c34\u80bf\u7684\u6297VEGF\u7c7b\u836f\u7269\u3002<\/strong><\/span><\/p>\n


<\/p>\n

2018\u5e745\u67088\u65e5\uff0c\u827e\u529b\u96c5\u518d\u6b21\u83b7\u5f97\u56fd\u5bb6\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40\u6279\u51c6\u7528\u4e8e\u6cbb\u7597\u65b0\u751f\u8840\u7ba1\uff08\u6e7f\u6027\uff09\u5e74\u9f84\u76f8\u5173\u6027\u9ec4\u6591\u53d8\u6027\uff08nAMD\uff09\u3002<\/span><\/p>\n


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UCB<\/strong><\/span><\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n
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\n

2018\u5e746\u6708\uff0c\u4f18\u65f6\u6bd4\u5236\u836f\u516c\u53f8\uff08UCB\uff09\u7814\u53d1\u7684\u7528\u4e8e\u6cbb\u7597\u5e15\u91d1\u68ee\u75c5\u7684\u521b\u65b0\u836f\u7269\u4f18\u666e\u6d1b\u00ae\u83b7\u5f97\u4e2d\u56fd\u98df\u54c1\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40\u6279\u51c6\u5728\u4e2d\u56fd\u4e0a\u5e02\u3002<\/span><\/p>\n


<\/p>\n

\"\u3010\u8fdb\u53e3\u65b0\u836f\u8d8b\u52bf\u3011\u8de8\u56fd\u5236\u836f\u4f01\u4e1a\u8fdb\u5165\u65b0\u836f\u6536\u83b7\u5bc6\u96c6\u671f*\"<\/p>\n<\/section>\n

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<\/p>\n<\/section>\n

\n

\u4f18\u666e\u6d1b<\/span>\u00ae\u662f\u7b2c\u4e00\u4e2a\u6cbb\u7597\u5e15\u91d1\u68ee\u75c5\u7684\u8d34\u5242\uff0c\u4e0d\u540c\u4e8e\u5e02\u573a\u4e0a\u6240\u6709\u6cbb\u7597\u65b9\u6848\u7684\u7ed9\u836f\u9014\u5f84\u3002<\/span><\/p>\n<\/section>\n

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\n

\"\u3010\u8fdb\u53e3\u65b0\u836f\u8d8b\u52bf\u3011\u8de8\u56fd\u5236\u836f\u4f01\u4e1a\u8fdb\u5165\u65b0\u836f\u6536\u83b7\u5bc6\u96c6\u671f*\"<\/p>\n<\/section>\n

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<\/p>\n<\/section>\n

\n

2018\u5e744\u670817\u65e5\uff0c<\/span>\u6069\u83b1\u745e\u00ae\uff08\u4f0a\u6c99\u4f50\u7c73\uff09<\/span><\/strong>\u6b63\u5f0f\u83b7\u5f97\u56fd\u5bb6\u98df\u54c1\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u603b\u5c40\uff08CFDA\uff09\u7684\u6279\u51c6\uff0c\u5c06<\/span>\u8054\u5408\u6765\u90a3\u5ea6\u80fa\u548c\u5730\u585e\u7c73\u677e<\/span><\/strong>\u4f5c\u4e3a<\/span>\u9996\u4e2a\u5168\u53e3\u670d\u6cbb\u7597\u65b9\u6848<\/span><\/strong>\uff0c\u7528\u4e8e\u6cbb\u7597\u5df2\u63a5\u53d7\u8fc7\u81f3\u5c11\u4e00\u79cd\u65e2\u5f80\u6cbb\u7597\u7684\u591a\u53d1\u6027\u9aa8\u9ad3\u7624\u6210\u4eba\u60a3\u8005\u3002<\/span><\/span><\/p>\n


<\/p>\n

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\u53c2\u8003\uff1a<\/span><\/strong><\/span><\/p>\n

CNDA\/CDE\uff1b<\/span><\/h1>\n

\u836f\u878d\u6570\u636e\uff0c<\/span>Pharnex  Datamonitor;<\/span><\/span><\/p>\n

\u76f8\u5173\u516c\u53f8\u516c\u5f00\u62ab\u9732\u7b49\u3002<\/span><\/p>\n


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\u836f\u878d\u5708\u4e3a\u836f\u7269\u7b80\u8baf\u5408\u4f5c\u5e73\u53f0.<\/span>
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\n<\/section>\n<\/section>\n<\/section><\/div>\n","protected":false},"excerpt":{"rendered":"

Research\u533b\u836f\u4ebaDaniel\u5206\u4eab\u3002 \u65e5\u672c\u5927\u51a2 \u5fb7\u62c9\u9a6c\u5c3c\u7247\uff0cDelamanid Tablets\u3002 2018 […]<\/p>\n","protected":false},"author":1,"featured_media":38509,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[2],"tags":[],"_links":{"self":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/38508"}],"collection":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/comments?post=38508"}],"version-history":[{"count":1,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/38508\/revisions"}],"predecessor-version":[{"id":38528,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/38508\/revisions\/38528"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/media\/38509"}],"wp:attachment":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/media?parent=38508"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/categories?post=38508"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/tags?post=38508"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}