{"id":39094,"date":"2018-08-22T01:00:00","date_gmt":"2018-09-17T06:27:49","guid":{"rendered":"http:\/\/www.05921.net\/index.php\/2018\/09\/17\/car-t%e7%94%9f%e4%ba%a7%e8%bf%87%e7%a8%8b%e7%9a%84%e8%b4%a8%e9%87%8f%e6%8e%a7%e5%88%b6\/"},"modified":"2018-09-17T14:28:15","modified_gmt":"2018-09-17T06:28:15","slug":"car-t%e7%94%9f%e4%ba%a7%e8%bf%87%e7%a8%8b%e7%9a%84%e8%b4%a8%e9%87%8f%e6%8e%a7%e5%88%b6","status":"publish","type":"post","link":"https:\/\/www.05921.net\/index.php\/39094\/","title":{"rendered":"CAR-T\u751f\u4ea7\u8fc7\u7a0b\u7684\u8d28\u91cf\u63a7\u5236"},"content":{"rendered":"<div class=\"bpp-post-content\">\n<p style=\"text-align: center;\"><span style=\"font-size: 15px;background-color: rgb(255, 255, 255);color: rgb(62, 62, 62);text-align: left;widows: 1;\"><\/span><\/p>\n<p><span style=\"font-size: 15px;\"><\/span><\/p>\n<p style=\"text-align: center;\"><img class=\"\"      style=\"\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/09\/4-1537165670.gif\" alt=\"CAR-T\u751f\u4ea7\u8fc7\u7a0b\u7684\u8d28\u91cf\u63a7\u5236\" title=\"CAR-T\u751f\u4ea7\u8fc7\u7a0b\u7684\u8d28\u91cf\u63a7\u5236\"  \/><\/p>\n<p><span style=\"font-size: 15px;\"><\/span><br  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><span style=\"max-width: 100%;color: rgb(73, 73, 73);font-family: Helvetica;font-size: 15px;line-height: 1.75em;box-sizing: border-box !important;word-wrap: break-word !important;\">\u5bf9\u4e8eCAR-T\u7ec6\u80de\u7597\u6cd5\u6765\u8bf4\uff0c2017\u5e74\u662f\u5177\u6709\u91cc\u7a0b\u7891\u610f\u4e49\u7684\u5e74\u4efd\u30022017\u5e748\u670831\u65e5\uff0cFDA\u6279\u51c6\u9996\u4e2aCAR-T\u7597\u6cd5Kymriah\u4e0a\u5e02\uff0c\u8bfa\u534e\u4e3a\u5176\u5b9a\u4ef747.5\u4e07\u7f8e\u5143\uff1b2017\u5e7410\u670819\u65e5\uff0cFDA\u6279\u51c6\u7b2c\u4e8c\u6b3eCAR-T\u7597\u6cd5Yescarta\u4e0a\u5e02\uff0cKite Pharma\u4e3a\u5176\u5b9a\u4ef737.3\u4e07\u7f8e\u5143\u3002<\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/p>\n<section  label=\"Powered by 135editor.com\" style=\"max-width: 100%;color: rgb(51, 51, 51);\">\n<section  label=\"Powered by 135editor.com\" style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\">\n<section class=\"\"     style=\"max-width: 100%;box-sizing: border-box;border-width: 0px;border-style: none;border-color: initial;word-wrap: break-word !important;\">\n<section  style=\"margin: 10px auto;max-width: 100%;width: 20em;text-align: center;box-sizing: border-box !important;word-wrap: break-word !important;\">\n<section style=\"padding: 6px;max-width: 100%;color: rgb(255, 255, 255);transform: rotate(360deg);background-color: rgb(130, 215, 218);box-sizing: border-box !important;word-wrap: break-word !important;\">\n<section style=\"padding: 10px;max-width: 100%;box-sizing: border-box;border-width: 1px;border-style: dashed;border-color: white;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 15px;box-sizing: border-box !important;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\">CAR-T \u751f\u4ea7\u5de5\u827a\u590d\u6742\u3001\u8981\u6c42\u9ad8<\/strong><\/span><\/section>\n<\/section>\n<section  style=\"margin-top: -1.8em;max-width: 100%;width: 20em;height: 3em;background-image: url('http:\/\/www.05921.net\/wp-content\/uploads\/2018\/09\/5-1537165695.png');background-size: 100%;background-repeat: no-repeat;box-sizing: border-box !important;word-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><span style=\"max-width: 100%;font-size: 15px;font-family: Helvetica;color: rgb(73, 73, 73);box-sizing: border-box !important;word-wrap: break-word !important;\">CAR-T\u7597\u6cd5\u4e0d\u540c\u4e8e\u4f20\u7edf\u836f\u7269\uff0c\u662f\u4e00\u79cd\u57fa\u4e8e\u6574\u5408\u4e86CAR\u57fa\u56e0\u7684\u81ea\u4f53T\u7ec6\u80de\u7597\u6cd5\u3002\u8fd9\u610f\u5473\u7740CAR-T\u5fc5\u987b\u5728\u5c3d\u53ef\u80fd\u77ed\u7684\u65f6\u95f4\u5185\u5b8c\u6210\u62bd\u8840\u3001\u5206\u79bb\u3001\u6fc0\u6d3b\u3001\u8f6c\u67d3\u3001\u6269\u589e\u3001\u5236\u5242\u3001\u653e\u884c\u3001\u51bb\u5e72\u3001\u8fd0\u8f93\u548c\u7ed9\u836f\u3002<\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><span style=\"max-width: 100%;font-size: 15px;font-family: Helvetica;color: rgb(73, 73, 73);box-sizing: border-box !important;word-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><img loading=\"lazy\" class=\"\"      height=\"462.6pt\" width=\"415.3pt\"  style=\"box-sizing: border-box !important;word-wrap: break-word !important;visibility: visible !important;width: 668px !important;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/09\/2-1537165670.jpeg\" alt=\"CAR-T\u751f\u4ea7\u8fc7\u7a0b\u7684\u8d28\u91cf\u63a7\u5236\" title=\"CAR-T\u751f\u4ea7\u8fc7\u7a0b\u7684\u8d28\u91cf\u63a7\u5236\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><span style=\"max-width: 100%;font-size: 15px;font-family: Helvetica;color: rgb(73, 73, 73);box-sizing: border-box !important;word-wrap: break-word !important;\">\u8bfa\u534e\u3001Juno\u3001Kite\u4e09\u5de8\u5934\u7684\u751f\u4ea7\u5de5\u827a\u7565\u6709\u533a\u522b\uff0c\u9009\u7528\u7684\u751f\u4ea7\u7cfb\u7edf\u4e5f\u6709\u6240\u5dee\u5f02\u3002<\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><img loading=\"lazy\" class=\"\"      height=\"319.75pt\" width=\"415.3pt\"  style=\"background-color: rgb(238, 237, 235);border-width: 1px;border-style: solid;border-color: rgb(238, 237, 235);background-size: 22px;background-position: center center;background-repeat: no-repeat;height: 514.308px !important;box-sizing: border-box !important;word-wrap: break-word !important;visibility: visible !important;width: 668px !important;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/09\/1-1537165670.jpeg\" alt=\"CAR-T\u751f\u4ea7\u8fc7\u7a0b\u7684\u8d28\u91cf\u63a7\u5236\" title=\"CAR-T\u751f\u4ea7\u8fc7\u7a0b\u7684\u8d28\u91cf\u63a7\u5236\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><span style=\"max-width: 100%;font-size: 15px;font-family: Helvetica;color: rgb(73, 73, 73);box-sizing: border-box !important;word-wrap: break-word !important;\">\u4ee5\u8bfa\u534e\u7684\u751f\u4ea7\u5de5\u827a\u4e3a\u4f8b\uff0c\u5176\u7ec6\u80de\u7597\u6cd5\u751f\u4ea7\u8f66\u95f4\u5360\u573017\u4e07\u5e73\u65b9\u82f1\u5c3a\uff0817000\u5e73\u7c73\uff09\u3002\u4e34\u5e8a\u7814\u7a76\u671f\u95f4\u5171\u751f\u4ea7\u8d85\u8fc7250\u4e2a\u6279\u6b21\u3002<\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><img class=\"\"       style=\"background-color: rgb(238, 237, 235);border-width: 1px;border-style: solid;border-color: rgb(238, 237, 235);background-size: 22px;background-position: center center;background-repeat: no-repeat;height: 342.409px !important;box-sizing: border-box !important;word-wrap: break-word !important;visibility: visible !important;width: 677px !important;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/09\/1-1537165671.jpg\" alt=\"CAR-T\u751f\u4ea7\u8fc7\u7a0b\u7684\u8d28\u91cf\u63a7\u5236\" title=\"CAR-T\u751f\u4ea7\u8fc7\u7a0b\u7684\u8d28\u91cf\u63a7\u5236\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><span style=\"max-width: 100%;font-size: 15px;font-family: Helvetica;color: rgb(73, 73, 73);box-sizing: border-box !important;word-wrap: break-word !important;\">\u8bfa\u534eCAR-T\u751f\u4ea7\u8f66\u95f4\u4f7f\u7528\u7684\u7cfb\u7edf\u5305\u62ecDynabeads CD3\/CD28\u7ec6\u80de\u6cbb\u7597\u7cfb\u7edfCTS\uff08\u8d5b\u9ed8\u98de\uff09\u3001Elutra\u3001Cell Saver\u00ae 5 (Haemonetics)\u548cSepax\u2122 Automated Cell Processing System (Biosafe)\u7b49\u3002<\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><img class=\"\"         width=\"35%\"  style=\"background-color: rgb(238, 237, 235);border-width: 1px;border-style: solid;border-color: rgb(238, 237, 235);background-size: 22px;background-position: center center;background-repeat: no-repeat;height: 163.026px !important;box-sizing: border-box !important;word-wrap: break-word !important;visibility: visible !important;width: 233.797px !important;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/09\/9-1537165671.jpeg\" alt=\"CAR-T\u751f\u4ea7\u8fc7\u7a0b\u7684\u8d28\u91cf\u63a7\u5236\" title=\"CAR-T\u751f\u4ea7\u8fc7\u7a0b\u7684\u8d28\u91cf\u63a7\u5236\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><span style=\"max-width: 100%;font-family: Helvetica;font-size: 9pt;color: rgb(214, 214, 214);box-sizing: border-box !important;word-wrap: break-word !important;\">Dynabeads CD3\/CD28 CTS<\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/p>\n<section  label=\"Powered by 135editor.com\" style=\"max-width: 100%;color: rgb(51, 51, 51);\">\n<section  label=\"Powered by 135editor.com\" style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\">\n<section class=\"\"     style=\"max-width: 100%;box-sizing: border-box;border-width: 0px;border-style: none;border-color: initial;word-wrap: break-word !important;\">\n<section  style=\"margin: 10px auto;max-width: 100%;width: 20em;text-align: center;box-sizing: border-box !important;word-wrap: break-word !important;\">\n<section style=\"padding: 6px;max-width: 100%;color: rgb(255, 255, 255);transform: rotate(360deg);background-color: rgb(130, 215, 218);box-sizing: border-box !important;word-wrap: break-word !important;\">\n<section style=\"padding: 10px;max-width: 100%;box-sizing: border-box;border-width: 1px;border-style: dashed;border-color: white;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 15px;box-sizing: border-box !important;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\">CAR-T\u8d28\u91cf\u63a7\u5236\u6210\u672c\u9ad8<\/strong><\/span><\/section>\n<\/section>\n<section  style=\"margin-top: -1.8em;max-width: 100%;width: 20em;height: 3em;background-image: url('http:\/\/www.05921.net\/wp-content\/uploads\/2018\/09\/5-1537165695.png');background-size: 100%;background-repeat: no-repeat;box-sizing: border-box !important;word-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><span style=\"max-width: 100%;font-size: 15px;font-family: Helvetica;color: rgb(73, 73, 73);box-sizing: border-box !important;word-wrap: break-word !important;\">\u6b64\u5916\u8fd8\u8981\u6ce8\u610f\uff0c\u81ea\u4f53T\u7ec6\u80de\u7597\u6cd5\u4e5f\u610f\u5473\u7740\u6bcf\u4e2a\u4ea7\u54c1\u90fd\u662f\u72ec\u7acb\u6279\u6b21\uff0c\u9700\u8981\u5b8c\u6574\u7684\u653e\u884c\u68c0\u6d4b\u3002\u636e\u76f8\u5173\u4e13\u5bb6\u4f30\u8ba1\uff0cCAR-T\u7ec6\u80de\u7684\u5de5\u827a\u6210\u672c\u7ea61.5\u4e07\u7f8e\u5143\uff0c\u800c\u5206\u6790\u8d28\u63a7\u7684\u6210\u672c\u5219\u53ef\u80fd\u9ad8\u8fbe5\u4e07\u7f8e\u5143\u4ee5\u4e0a\u3002<\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><span style=\"max-width: 100%;font-size: 15px;font-family: Helvetica;color: rgb(73, 73, 73);box-sizing: border-box !important;word-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><img loading=\"lazy\" class=\"\"      height=\"212.21758pt\" width=\"239.02487pt\"  style=\"background-color: rgb(238, 237, 235);border-width: 1px;border-style: solid;border-color: rgb(238, 237, 235);background-size: 22px;background-position: center center;background-repeat: no-repeat;height: 593.064px !important;box-sizing: border-box !important;word-wrap: break-word !important;visibility: visible !important;width: 668px !important;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/09\/8-1537165671.jpg\" alt=\"CAR-T\u751f\u4ea7\u8fc7\u7a0b\u7684\u8d28\u91cf\u63a7\u5236\" title=\"CAR-T\u751f\u4ea7\u8fc7\u7a0b\u7684\u8d28\u91cf\u63a7\u5236\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><span style=\"max-width: 100%;font-size: 15px;font-family: Helvetica;color: rgb(73, 73, 73);box-sizing: border-box !important;word-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><span style=\"max-width: 100%;font-size: 15px;font-family: Helvetica;color: rgb(73, 73, 73);box-sizing: border-box !important;word-wrap: break-word !important;\">\u90a3\u4e48\uff0cCAR-T\u7684\u653e\u884c\u9700\u8981\u505a\u54ea\u4e9b\u68c0\u6d4b\u5462\uff1f\u6839\u636eCAR-T\u7684\u4f5c\u7528\u673a\u5236\u548c\u4ea7\u54c1\u7279\u70b9\uff0c\u5176\u8d28\u91cf\u63a7\u5236\u65e0\u5916\u4e4e\u4ee5\u4e0b\u51e0\u4e2a\u65b9\u9762\uff1a<\/span><\/p>\n<ul class=\"list-paddingleft-2\" style=\"list-style-type: circle;\">\n<li>\n<p style=\"max-width: 100%;min-height: 1em;line-height: 1.75em;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 15px;font-family: Helvetica;box-sizing: border-box !important;word-wrap: break-word !important;\">Potency \u6548\u4ef7<\/span><\/p>\n<\/li>\n<li>\n<p style=\"max-width: 100%;min-height: 1em;line-height: 1.75em;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 15px;font-family: Helvetica;box-sizing: border-box !important;word-wrap: break-word !important;\">Transduction Efficiency \u8f6c\u67d3\u6548\u7387<\/span><\/p>\n<\/li>\n<li>\n<p style=\"max-width: 100%;min-height: 1em;line-height: 1.75em;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 15px;font-family: Helvetica;box-sizing: border-box !important;word-wrap: break-word !important;\">Identity \u9274\u522b<\/span><\/p>\n<\/li>\n<li>\n<p style=\"max-width: 100%;min-height: 1em;line-height: 1.75em;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 15px;font-family: Helvetica;box-sizing: border-box !important;word-wrap: break-word !important;\">T cell subsets T\u7ec6\u80de\u4e9a\u7fa4<\/span><\/p>\n<\/li>\n<li>\n<p style=\"max-width: 100%;min-height: 1em;line-height: 1.75em;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 15px;font-family: Helvetica;box-sizing: border-box !important;word-wrap: break-word !important;\">Safty \u5b89\u5168\u6027<br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/span><\/p>\n<\/li>\n<\/ul>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><span style=\"max-width: 100%;font-size: 15px;font-family: Helvetica;font-weight: bold;color: rgb(73, 73, 73);box-sizing: border-box !important;word-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><span style=\"max-width: 100%;color: rgb(130, 215, 218);box-sizing: border-box !important;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 15px;font-family: Helvetica;box-sizing: border-box !important;word-wrap: break-word !important;\">Potency \u6548\u4ef7<\/span><\/strong><\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><span style=\"max-width: 100%;font-size: 15px;font-family: Helvetica;color: rgb(73, 73, 73);box-sizing: border-box !important;word-wrap: break-word !important;\">CAR-T\u7684Potency\u4e3b\u8981\u662fT\u7ec6\u80de\u7684\u6fc0\u6d3b\u7a0b\u5ea6\uff0c\u7531\u4e8eT\u7ec6\u80de\u7684\u6fc0\u6d3b\u6d89\u53ca\u4e00\u7cfb\u5217\u7684\u7ec6\u80de\u56e0\u5b50\u4ee5\u53ca\u764c\u7ec6\u80de\u7684\u6740\u4f24\uff0c\u56e0\u800c\u771f\u5b9e\u6548\u4ef7\u5f80\u5f80\u96be\u4ee5\u83b7\u5f97\u3002\u901a\u5e38\u4f1a\u9009\u53d6\u6709\u4ee3\u8868\u6027\u5982IFN-\u03b3\u7684\u8868\u8fbe\u6765\u8bc4\u4f30T\u7ec6\u80de\u7684\u6fc0\u6d3b\uff0c\u5728\u4e34\u5e8a\u8bd5\u9a8c\u4e2d\u53d1\u73b0IFN-\u03b3\u7684\u53d8\u5f02\u6027\u975e\u5e38\u5927\uff08\u4e0b\u56fe\u4e3aKymriah\u7684\u6570\u636e\uff09\uff0c\u5f88\u96be\u76f4\u63a5\u4e0eCAR-T \u7684\u5b89\u5168\u6027\u548c\u6709\u6548\u6027\u5173\u8054\u3002<\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><img loading=\"lazy\" class=\"\"      height=\"199.75583pt\" width=\"307.03394pt\"  style=\"background-color: rgb(238, 237, 235);border-width: 1px;border-style: solid;border-color: rgb(238, 237, 235);background-size: 22px;background-position: center center;background-repeat: no-repeat;height: 435.244px !important;box-sizing: border-box !important;word-wrap: break-word !important;visibility: visible !important;width: 668px !important;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/09\/2-1537165672.jpeg\" alt=\"CAR-T\u751f\u4ea7\u8fc7\u7a0b\u7684\u8d28\u91cf\u63a7\u5236\" title=\"CAR-T\u751f\u4ea7\u8fc7\u7a0b\u7684\u8d28\u91cf\u63a7\u5236\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><span style=\"max-width: 100%;color: rgb(130, 215, 218);box-sizing: border-box !important;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 15px;font-family: Helvetica;box-sizing: border-box !important;word-wrap: break-word !important;\">Transduction Efficiency \u8f6c\u67d3\u6548\u7387<\/span><\/strong><\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><span style=\"max-width: 100%;font-size: 15px;font-family: Helvetica;color: rgb(73, 73, 73);box-sizing: border-box !important;word-wrap: break-word !important;\">CAR\u57fa\u56e0\u901a\u8fc7\u6162\u75c5\u6bd2\u8d28\u7c92\u8f6c\u67d3\uff0c\u6574\u5408\u5230T\u7ec6\u80de\u57fa\u56e0\u4e2d\u3002\u56e0\u6b64\u8f6c\u67d3\u6548\u7387\u4e00\u822c\u901a\u8fc7\u8d28\u7c92\u62f7\u8d1d\u6570\uff08VCN\/cell\uff09\u548cCAR\u8868\u8fbe\u6c34\u5e73\u6765\u8bc4\u4f30\u3002<br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><span style=\"max-width: 100%;font-size: 15px;font-family: Helvetica;color: rgb(73, 73, 73);box-sizing: border-box !important;word-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><span style=\"max-width: 100%;font-size: 15px;font-family: Helvetica;color: rgb(73, 73, 73);box-sizing: border-box !important;word-wrap: break-word !important;\">\u8d28\u7c92\u62f7\u8d1d\u6570\u901a\u8fc7qPCR\u68c0\u6d4b\uff0c\u5f97\u5230\u76f8\u5bf9\u4e8eCAR\u9633\u6027\u7ec6\u80de\u6570\u6216\u8005\u603b\u7ec6\u80de\u6570\u7684\u8d28\u7c92\u62f7\u8d1d\u6570\u3002\u751f\u4ea7\u8fc7\u7a0b\u4e2d\u53ef\u4ee5\u901a\u8fc7\u8c03\u6574\u6162\u75c5\u6bd2\u8d28\u7c92\u6570\u4e0e\u603b\u7ec6\u80de\u6570\u6765\u4f18\u5316\u8d28\u7c92\u62f7\u8d1d\u6570\u7ec6\u80de\u6570\u6bd4\u3002<\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><img loading=\"lazy\" class=\"\"      height=\"250.1pt\" width=\"415.3pt\"  style=\"background-color: rgb(238, 237, 235);border-width: 1px;border-style: solid;border-color: rgb(238, 237, 235);background-size: 22px;background-position: center center;background-repeat: no-repeat;height: 402.358px !important;box-sizing: border-box !important;word-wrap: break-word !important;visibility: visible !important;width: 668px !important;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/09\/7-1537165672.png\" alt=\"CAR-T\u751f\u4ea7\u8fc7\u7a0b\u7684\u8d28\u91cf\u63a7\u5236\" title=\"CAR-T\u751f\u4ea7\u8fc7\u7a0b\u7684\u8d28\u91cf\u63a7\u5236\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><span style=\"max-width: 100%;font-size: 15px;font-family: Helvetica;color: rgb(73, 73, 73);box-sizing: border-box !important;word-wrap: break-word !important;\">CAR\u8868\u8fbe\u6c34\u5e73\u53ef\u4ee5\u901a\u8fc7\u6d41\u5f0f\u7ec6\u80de\u672f\u68c0\u6d4bCAR\u9633\u6027T\u7ec6\u80de\u767e\u5206\u6bd4\u6765\u8bc4\u4f30\u3002\u76ee\u524dCAR\u9633\u6027T\u7ec6\u80de\u7684\u767e\u5206\u6bd4\u63a7\u5236\u7ecf\u9a8c\u6709\u9650\uff0cKymriah\u7684CAR\u9633\u6027T\u7ec6\u80de\u767e\u5206\u6bd4\u6279\u6b21\u5dee\u5f02\u6027\u8f83\u5927\u3002\u5c3d\u7ba1CAR\u9634\u6027T\u7ec6\u80de\u5bf9\u5b89\u5168\u6027\u548c\u6709\u6548\u6027\u7684\u5f71\u54cd\u4e0d\u662f\u5341\u5206\u6e05\u695a\uff0c\u4f46\u4e00\u822c\u4e0d\u5c06\u5176\u4f5c\u4e3a\u6742\u8d28\u5bf9\u5f85\uff0c\u4e5f\u4e0d\u8ba4\u4e3a\u5176\u4ea7\u751f\u660e\u663e\u7684\u5b89\u5168\u98ce\u9669\u3002<\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><img loading=\"lazy\" class=\"\"      height=\"289.4122pt\" width=\"415.3pt\"  style=\"background-color: rgb(238, 237, 235);border-width: 1px;border-style: solid;border-color: rgb(238, 237, 235);background-size: 22px;background-position: center center;background-repeat: no-repeat;height: 465.468px !important;box-sizing: border-box !important;word-wrap: break-word !important;visibility: visible !important;width: 668px !important;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/09\/3-1537165672.jpg\" alt=\"CAR-T\u751f\u4ea7\u8fc7\u7a0b\u7684\u8d28\u91cf\u63a7\u5236\" title=\"CAR-T\u751f\u4ea7\u8fc7\u7a0b\u7684\u8d28\u91cf\u63a7\u5236\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><span style=\"max-width: 100%;color: rgb(130, 215, 218);box-sizing: border-box !important;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 15px;font-family: Helvetica;box-sizing: border-box !important;word-wrap: break-word !important;\">Identity \u9274\u522b<\/span><\/strong><\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><span style=\"max-width: 100%;font-size: 15px;font-family: Helvetica;color: rgb(73, 73, 73);box-sizing: border-box !important;word-wrap: break-word !important;\">\u9274\u522b\u8981\u4fdd\u8bc1\u75c5\u4eba\u4f7f\u7528\u7684\u4e3a\u6765\u81ea\u81ea\u8eab\u7684\u7ec6\u80de\uff0cKymriah\u540c\u65f6\u8fdb\u4e00\u6b65\u901a\u8fc7qPCR\u68c0\u6d4bVCN\u3001\u6d41\u5f0f\u7ec6\u80de\u672f\u68c0\u6d4bCAR\u8868\u8fbe\u6765\u9274\u522b\u5176\u4e3a\u8868\u8fbeCAR\u7684\u81ea\u8eabT\u7ec6\u80de\u3002<\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><span style=\"max-width: 100%;color: rgb(130, 215, 218);box-sizing: border-box !important;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 15px;font-family: Helvetica;box-sizing: border-box !important;word-wrap: break-word !important;\">T cell subsets T\u7ec6\u80de\u4e9a\u7fa4<\/span><\/strong><\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><span style=\"max-width: 100%;font-size: 15px;font-family: Helvetica;color: rgb(73, 73, 73);box-sizing: border-box !important;word-wrap: break-word !important;\">\u4ece\u5916\u5468\u8840\u5206\u79bb\u7684PBMC\uff0c\u56e0\u4e2a\u4f53\u5dee\u5f02\u5176\u7ec6\u80de\u6210\u5206\u5dee\u5f02\u5f88\u5927\uff0c\u7ecf\u8fc7\u5206\u79bb\u3001\u7eaf\u5316\u6700\u7ec8\u90fd\u6210\u4e3a\u767e\u5206\u4e4b\u767e\u7684T\u7ec6\u80de\u3002<\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><img loading=\"lazy\" class=\"\"      height=\"308.25pt\" width=\"415.3pt\"  style=\"background-color: rgb(238, 237, 235);border-width: 1px;border-style: solid;border-color: rgb(238, 237, 235);background-size: 22px;background-position: center center;background-repeat: no-repeat;height: 495.781px !important;box-sizing: border-box !important;word-wrap: break-word !important;visibility: visible !important;width: 668px !important;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/09\/9-1537165673.jpeg\" alt=\"CAR-T\u751f\u4ea7\u8fc7\u7a0b\u7684\u8d28\u91cf\u63a7\u5236\" title=\"CAR-T\u751f\u4ea7\u8fc7\u7a0b\u7684\u8d28\u91cf\u63a7\u5236\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><span style=\"max-width: 100%;font-size: 15px;font-family: Helvetica;color: rgb(73, 73, 73);box-sizing: border-box !important;word-wrap: break-word !important;\">\u4f46T\u7ec6\u80de\u4e5f\u5305\u542b\u4e0d\u540c\u4e9a\u7fa4\uff0c\u5982CD4 T\u7ec6\u80de\u3001CD8 T\u7ec6\u80de\u3001\u8bb0\u5fc6\u6027T\u7ec6\u80de\u7b49\uff0c\u8fd9\u4e9b\u4e9a\u7fa4\u90fd\u6709\u7740\u4e0d\u540c\u7684\u751f\u7269\u5b66\u529f\u80fd\u3002Kymriah\u6bcf\u4e00\u6279\u6b21\u90fd\u4f1a\u68c0\u6d4bT\u7ec6\u80de\u4e9a\u7fa4\u7ec4\u6210\uff0c\u4f46\u6ca1\u6709\u4f5c\u4e3a\u653e\u884c\u6807\u51c6\uff1bJuno\u5219\u63a7\u5236CD4 T\u7ec6\u80de\u4e0eCD8 T\u7ec6\u80de\u7684\u6bd4\u4f8b\u4e3a1:1\u3002T\u7ec6\u80de\u4e9a\u7fa4\u5bf9\u4e8e\u5b89\u5168\u6027\u548c\u6709\u6548\u6027\u7684\u5f71\u54cd\u5f85\u8fdb\u4e00\u6b65\u6df1\u5165\u7814\u7a76\u3002<\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><span style=\"max-width: 100%;color: rgb(130, 215, 218);box-sizing: border-box !important;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 15px;font-family: Helvetica;box-sizing: border-box !important;word-wrap: break-word !important;\">Safety \u5b89\u5168\u6027<\/span><\/strong><\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><span style=\"max-width: 100%;font-size: 15px;font-family: Helvetica;color: rgb(73, 73, 73);box-sizing: border-box !important;word-wrap: break-word !important;\">\u5b89\u5168\u6027\u9664\u4e86\u5e38\u89c4\u7684\u5185\u6bd2\u7d20\u3001\u652f\u539f\u4f53\u53ca\u65e0\u83cc\u5916\uff0c\u4e3b\u8981\u662f\u56f4\u7ed5\u6162\u75c5\u6bd2\u8f7d\u4f53\u7684\u5b89\u5168\u6027\u8003\u91cf\u3002\u7528\u4e8e\u8f6c\u67d3\u7684\u6162\u75c5\u6bd2\u5fc5\u987b\u4fdd\u8bc1\u9ad8\u8d28\u91cf\uff0c\u907f\u514d\u5b58\u5728\u5177\u6709\u590d\u5236\u80fd\u529b\u7684\u75c5\u6bd2\uff08RCL\uff09\u3001\u4f4e\u98ce\u9669\u7684\u6574\u5408profile\u3002<\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><img loading=\"lazy\" class=\"\"      height=\"200.62796pt\" width=\"368.81384pt\"  style=\"background-color: rgb(238, 237, 235);border-width: 1px;border-style: solid;border-color: rgb(238, 237, 235);background-size: 22px;background-position: center center;background-repeat: no-repeat;height: 363.411px !important;box-sizing: border-box !important;word-wrap: break-word !important;visibility: visible !important;width: 668px !important;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/09\/7-1537165673.jpg\" alt=\"CAR-T\u751f\u4ea7\u8fc7\u7a0b\u7684\u8d28\u91cf\u63a7\u5236\" title=\"CAR-T\u751f\u4ea7\u8fc7\u7a0b\u7684\u8d28\u91cf\u63a7\u5236\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><span style=\"max-width: 100%;font-family: Helvetica;font-size: 15px;color: rgb(73, 73, 73);box-sizing: border-box !important;word-wrap: break-word !important;\">\u6162\u75c5\u6bd2\u8f7d\u4f53\u7684\u68c0\u6d4b\u5206\u6790\u5305\u62ec\uff1a<\/span><\/p>\n<ul class=\"list-paddingleft-2\" style=\"list-style-type: circle;\">\n<li>\n<p style=\"max-width: 100%;min-height: 1em;line-height: 1.75em;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 15px;color: rgb(73, 73, 73);box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-family: Helvetica;color: rgb(62, 62, 62);box-sizing: border-box !important;word-wrap: break-word !important;\">\u5916\u89c2\uff1a\u8f7d\u4f53\u60ac\u6db2\u5916\u89c2\u5e94\u4fdd\u6301\u4e00\u81f4\u6027\uff1b<\/span><\/span><\/p>\n<\/li>\n<li>\n<p style=\"max-width: 100%;min-height: 1em;line-height: 1.75em;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 15px;color: rgb(73, 73, 73);box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-family: Helvetica;color: rgb(62, 62, 62);box-sizing: border-box !important;word-wrap: break-word !important;\">\u9274\u522b\uff1aqPCR\u68c0\u6d4bCAR\u57fa\u56e0\uff1b<\/span><\/span><\/p>\n<\/li>\n<li>\n<p style=\"max-width: 100%;min-height: 1em;line-height: 1.75em;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 15px;color: rgb(73, 73, 73);box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-family: Helvetica;color: rgb(62, 62, 62);box-sizing: border-box !important;word-wrap: break-word !important;\">\u5b89\u5168\u6027\uff1a\u907f\u514d\u5fae\u751f\u7269\u6c61\u67d3\u3001RCL\u6c61\u67d3\uff1b<\/span><\/span><\/p>\n<\/li>\n<li>\n<p style=\"max-width: 100%;min-height: 1em;line-height: 1.75em;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 15px;color: rgb(73, 73, 73);box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-family: Helvetica;color: rgb(62, 62, 62);box-sizing: border-box !important;word-wrap: break-word !important;\">\u7eaf\u5ea6\uff1a\u68c0\u6d4b\u8f7d\u4f53\u548c\u6742\u8d28\u91cf\uff1b<\/span><\/span><\/p>\n<\/li>\n<li>\n<p style=\"max-width: 100%;min-height: 1em;line-height: 1.75em;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 15px;color: rgb(73, 73, 73);box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-family: Helvetica;color: rgb(62, 62, 62);box-sizing: border-box !important;word-wrap: break-word !important;\">\u5b9a\u91cf\uff1ap24\u86cb\u767d\u5206\u6790\u548c\u75c5\u6bd2RNA\u68c0\u6d4b\uff1b<\/span><\/span><\/p>\n<\/li>\n<li>\n<p style=\"max-width: 100%;min-height: 1em;line-height: 1.75em;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 15px;color: rgb(73, 73, 73);box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-family: Helvetica;color: rgb(62, 62, 62);box-sizing: border-box !important;word-wrap: break-word !important;\">\u751f\u7269\u6d3b\u6027\uff1a\u76ee\u6807\u7ec6\u80de\u8f6c\u67d3\u7684\u6548\u7387\u6d4b\u5b9a\u3002<\/span><br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/span><\/p>\n<\/li>\n<\/ul>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/p>\n<section  label=\"Powered by 135editor.com\" style=\"max-width: 100%;color: rgb(51, 51, 51);\">\n<section  label=\"Powered by 135editor.com\" style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\">\n<section class=\"\"     style=\"max-width: 100%;box-sizing: border-box;border-width: 0px;border-style: none;border-color: initial;word-wrap: break-word !important;\">\n<section  style=\"margin: 10px auto;max-width: 100%;width: 20em;text-align: center;box-sizing: border-box !important;word-wrap: break-word !important;\">\n<section style=\"padding: 6px;max-width: 100%;color: rgb(255, 255, 255);transform: rotate(360deg);background-color: rgb(130, 215, 218);box-sizing: border-box !important;word-wrap: break-word !important;\">\n<section style=\"padding: 10px;max-width: 100%;box-sizing: border-box;border-width: 1px;border-style: dashed;border-color: white;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 15px;box-sizing: border-box !important;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\">CAR-T\u751f\u4ea7\u8f66\u95f4\u5b9e\u4f8b<\/strong><\/span><\/section>\n<\/section>\n<section  style=\"margin-top: -1.8em;max-width: 100%;width: 20em;height: 3em;background-image: url('http:\/\/www.05921.net\/wp-content\/uploads\/2018\/09\/5-1537165695.png');background-size: 100%;background-repeat: no-repeat;box-sizing: border-box !important;word-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><span style=\"max-width: 100%;color: rgb(73, 73, 73);font-family: Helvetica;font-size: 15px;box-sizing: border-box !important;word-wrap: break-word !important;\">CAR-T\u8f66\u95f4\u4e00\u822c\u5305\u62ec\u751f\u4ea7\u5355\u5143\u3001\u50a8\u5b58\u5355\u5143\u3001\u8d28\u63a7\u68c0\u6d4b\u5355\u5143\u7b49\uff0cCMO\u516c\u53f8\u8fd8\u4f1a\u6709\u6280\u672f\u8f6c\u79fb\u5355\u5143\u3002\u4e0b\u56fe\u5373MaSTherCell\u516c\u53f8\u7684CAR-T\u751f\u4ea7\u8f66\u95f4\u5e73\u9762\u56fe\uff0c\u6574\u4e2a\u8f66\u95f4\u7684\u5efa\u7b51\u9762\u79ef\u4e3a600\u33a1\u3002<\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><img loading=\"lazy\" class=\"\"      height=\"242.85pt\" width=\"415.3pt\"  style=\"background-color: rgb(238, 237, 235);border-width: 1px;border-style: solid;border-color: rgb(238, 237, 235);background-size: 22px;background-position: center center;background-repeat: no-repeat;height: 390.63px !important;box-sizing: border-box !important;word-wrap: break-word !important;visibility: visible !important;width: 668px !important;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/09\/6-1537165673.jpg\" alt=\"CAR-T\u751f\u4ea7\u8fc7\u7a0b\u7684\u8d28\u91cf\u63a7\u5236\" title=\"CAR-T\u751f\u4ea7\u8fc7\u7a0b\u7684\u8d28\u91cf\u63a7\u5236\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><span style=\"max-width: 100%;font-size: 15px;font-family: Helvetica;color: rgb(73, 73, 73);box-sizing: border-box !important;word-wrap: break-word !important;\">\u751f\u4ea7\u5355\u5143\u4e3b\u8981\u662fT\u7ec6\u80de\u7684\u5206\u79bb\u3001\u7eaf\u5316\u3001\u6fc0\u6d3b\u3001\u6269\u589e\u3001\u8fc7\u6ee4\u3001\u5236\u5242\u7b49\u3002MaSTherCell\u4e3a\u4e00\u5bb6CMO\u4f01\u4e1a\uff0c\u8003\u8651\u5230\u751f\u4ea7\u8fc7\u7a0b\u7684\u7075\u6d3b\u6027\uff0c\u751f\u4ea7\u90e8\u5206\u542b\u67092\u4e2a\u5b8c\u5168\u76f8\u540c\u7684\u751f\u4ea7\u5355\u5143\u3002\u6839\u636e\u7ea62\u5468\/\u6279\u7684\u751f\u4ea7\u5468\u671f\uff0c\u6bcf\u4e2a\u5355\u5143\u6bcf\u5e74\u53ef\u751f\u4ea7100-120\u6279\u6b21\u3002<\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><img loading=\"lazy\" class=\"\"      height=\"274.94403pt\" width=\"415.3pt\"  style=\"background-color: rgb(238, 237, 235);border-width: 1px;border-style: solid;border-color: rgb(238, 237, 235);background-size: 22px;background-position: center center;background-repeat: no-repeat;height: 442.226px !important;box-sizing: border-box !important;word-wrap: break-word !important;visibility: visible !important;width: 668px !important;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/09\/9-1537165674.jpg\" alt=\"CAR-T\u751f\u4ea7\u8fc7\u7a0b\u7684\u8d28\u91cf\u63a7\u5236\" title=\"CAR-T\u751f\u4ea7\u8fc7\u7a0b\u7684\u8d28\u91cf\u63a7\u5236\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><span style=\"max-width: 100%;font-size: 15px;font-family: Helvetica;color: rgb(73, 73, 73);box-sizing: border-box !important;word-wrap: break-word !important;\">QC\uff08\u8d28\u91cf\u63a7\u5236\uff09\u5355\u5143\u4e3b\u8981\u662fCAR-T\u7684\u653e\u884c\u68c0\u6d4b\uff0c\u5305\u62ec\u751f\u5316\u68c0\u6d4b\u3001\u5fae\u751f\u7269\u68c0\u6d4b\u3001\u7ec6\u80de\u5b66\u68c0\u6d4b\u3002\u751f\u5316\u68c0\u6d4b\u5b9e\u9a8c\u5ba4\u4e3b\u8981\u4f7f\u7528\u4e86Applied Biosysytems qPCR\u4eea\u7b49\u8bbe\u5907\uff0c\u7528\u4e8eCAR-T\u7684\u9274\u522b\u548c\u7eaf\u5ea6\u68c0\u6d4b\u3002\u7ec6\u80de\u5b66\u68c0\u6d4b\u5b9e\u9a8c\u5ba4\u4e3b\u8981\u4f7f\u7528\u5012\u7f6e\u663e\u5fae\u955c\u3001\u8367\u5149\u663e\u5fae\u955c\u3001\u5c42\u6d41\u7f69\u3001\u4e8c\u6c27\u5316\u78b3\u57f9\u517b\u7bb1\u3001qPCR\u4eea\u7b49\uff0c\u8fdb\u884c\u7ec6\u80de\u8ba1\u6570\u3001\u6d3b\u7387\u68c0\u6d4b\u3001\u4f53\u5916\u6548\u4ef7\u68c0\u6d4b\u4ee5\u53ca\u53ef\u80fd\u7684\u6742\u8d28\u5206\u6790\u7b49\u3002\u5fae\u751f\u7269\u68c0\u6d4b\u5b9e\u9a8c\u5ba4\u8d1f\u8d23\u5bf9\u73af\u5883\u7684\u76d1\u6d4b\uff0c\u4e3b\u8981\u8fdb\u884c\u603b\u538c\u6c27\u83cc\u7684\u8ba1\u6570\u3001\u9175\u6bcd\u548c\u9709\u83cc\u7684\u68c0\u6d4b\uff0c\u8d5b\u9ed8\u98de\u63d0\u4f9b\u652f\u539f\u4f53\u3001\u75c5\u6bd2\u68c0\u6d4b\u7cfb\u7edf\u53ca\u6b8b\u7559DNA\u3001\u6b8b\u7559\u86cb\u767d\u7b49\u7684\u68c0\u6d4b\u3002<\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><img loading=\"lazy\" class=\"\"      height=\"697.9pt\" width=\"351.25pt\"  style=\"box-sizing: border-box !important;word-wrap: break-word !important;visibility: visible !important;width: 668px !important;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/09\/0-1537165674.jpeg\" alt=\"CAR-T\u751f\u4ea7\u8fc7\u7a0b\u7684\u8d28\u91cf\u63a7\u5236\" title=\"CAR-T\u751f\u4ea7\u8fc7\u7a0b\u7684\u8d28\u91cf\u63a7\u5236\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><span style=\"max-width: 100%;font-size: 15px;font-family: Helvetica;box-sizing: border-box !important;word-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><span style=\"max-width: 100%;font-size: 15px;color: rgb(73, 73, 73);box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-family: Helvetica;color: rgb(62, 62, 62);box-sizing: border-box !important;word-wrap: break-word !important;\">\u50a8\u5b58\u5355\u5143\u7684\u9762\u79ef\u8d85\u8fc780\u33a1\uff0c\u4e3b\u8981\u8fdb\u884c\u6210\u54c1\u7684\u6807\u7b7e\u3001\u5305\u88c5\u3001\u50a8\u5b58\u7b49\u3002\u51b7\u5e93\u4e2d\u8fd8\u914d\u5907\u4e00\u4e9b-80<\/span><span style=\"max-width: 100%;font-family: \u5b8b\u4f53;color: rgb(62, 62, 62);box-sizing: border-box !important;word-wrap: break-word !important;\">\u2103<\/span><span style=\"max-width: 100%;font-family: Helvetica;color: rgb(62, 62, 62);box-sizing: border-box !important;word-wrap: break-word !important;\">\u51b0\u7bb1\uff0c\u7528\u4e8e\u75c5\u6bd2\u7684\u5b58\u653e\u3002\u6280\u672f\u5939\u5c42\u68c0\u6d4b\u73af\u5883\uff0c\u7b26\u5408GMP\u8981\u6c42\u3002<\/span><\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><img loading=\"lazy\" class=\"\"      height=\"697.9pt\" width=\"349.7pt\"  style=\"box-sizing: border-box !important;word-wrap: break-word !important;visibility: visible !important;width: 668px !important;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/09\/0-1537165695.jpeg\" alt=\"CAR-T\u751f\u4ea7\u8fc7\u7a0b\u7684\u8d28\u91cf\u63a7\u5236\" title=\"CAR-T\u751f\u4ea7\u8fc7\u7a0b\u7684\u8d28\u91cf\u63a7\u5236\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><span style=\"max-width: 100%;font-family: Helvetica;font-weight: bold;font-size: 15px;color: rgb(73, 73, 73);box-sizing: border-box !important;word-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/p>\n<section  label=\"Powered by 135editor.com\" style=\"max-width: 100%;color: rgb(51, 51, 51);\">\n<section  label=\"Powered by 135editor.com\" style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\">\n<section class=\"\"     style=\"max-width: 100%;box-sizing: border-box;border-width: 0px;border-style: none;border-color: initial;word-wrap: break-word !important;\">\n<section  style=\"margin: 10px auto;max-width: 100%;width: 20em;text-align: center;box-sizing: border-box !important;word-wrap: break-word !important;\">\n<section style=\"padding: 6px;max-width: 100%;color: rgb(255, 255, 255);transform: rotate(360deg);background-color: rgb(130, 215, 218);box-sizing: border-box !important;word-wrap: break-word !important;\">\n<section style=\"padding: 10px;max-width: 100%;box-sizing: border-box;border-width: 1px;border-style: dashed;border-color: white;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 15px;box-sizing: border-box !important;word-wrap: break-word !important;\">\u603b\u7ed3<\/span><\/section>\n<\/section>\n<section  style=\"margin-top: -1.8em;max-width: 100%;width: 20em;height: 3em;background-image: url('http:\/\/www.05921.net\/wp-content\/uploads\/2018\/09\/5-1537165695.png');background-size: 100%;background-repeat: no-repeat;box-sizing: border-box !important;word-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><span style=\"max-width: 100%;font-size: 15px;font-family: Helvetica;color: rgb(73, 73, 73);box-sizing: border-box !important;word-wrap: break-word !important;\">CAR-T\u7597\u6cd5\u7684\u7a81\u7834\u6027\u8fdb\u5c55\uff0c\u5e26\u52a8\u4e86CAR-T\u751f\u4ea7\u5de5\u827a\u7684\u5feb\u901f\u53d1\u5c55\uff0c\u7f29\u77ed\u751f\u4ea7\u5468\u671f\u3001\u964d\u4f4e\u751f\u4ea7\u6210\u672c\u6210\u4e3a\u6ee1\u8db3\u4e34\u5e8a\u9700\u6c42\u3001\u964d\u4f4e\u7528\u836f\u6210\u672c\u7684\u5fc5\u7136\u9009\u62e9\u3002\u5728CAR-T\u7684\u751f\u4ea7\u6210\u672c\u4e2d\uff0c\u5206\u6790\u8d28\u63a7\u5360\u5230\u4e86\u5f88\u5927\u6bd4\u4f8b\uff0c\u5efa\u7acb\u6210\u719f\u3001\u7b80\u4fbf\u3001\u6709\u6548\u7684\u653e\u884c\u68c0\u6d4b\u4f53\u7cfb\uff0c\u5bf9\u4e8eCAR-T\u7684\u666e\u53ca\u6709\u5f88\u91cd\u8981\u7684\u73b0\u5b9e\u610f\u4e49\u3002<\/span><\/p>\n<p style=\"white-space: normal;\"><br  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><span style=\"max-width: 100%;font-size: 12px;color: rgb(136, 147, 147);box-sizing: border-box !important;word-wrap: break-word !important;\">\u53c2\u8003\u8d44\u6599<\/span><\/p>\n<ul class=\"list-paddingleft-2\" style=\"list-style-type: circle;\">\n<li>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 12px;color: rgb(136, 147, 147);box-sizing: border-box !important;word-wrap: break-word !important;\">CTL019\u5ba1\u8bc4\u8d44\u6599\uff1b<\/span><\/p>\n<\/li>\n<li>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 12px;color: rgb(136, 147, 147);box-sizing: border-box !important;word-wrap: break-word !important;\">manufacturing of CAR T cells\uff0c 2016\uff1b<\/span><\/p>\n<\/li>\n<li>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 12px;color: rgb(136, 147, 147);box-sizing: border-box !important;word-wrap: break-word !important;\">Global Manufacturing of CAR T Cell Therapy(2017)\uff1bAutologous CAR-T Cell Manufacturing: &nbsp;Current Standing and Future Directions\uff1b<\/span><\/p>\n<\/li>\n<li>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 12px;color: rgb(136, 147, 147);box-sizing: border-box !important;word-wrap: break-word !important;\">Novartis\u3001Juno\u3001Kite\u3001MaSTherCell\u5b98\u7f51\u3002<\/span><\/p>\n<\/li>\n<\/ul>\n<p style=\"white-space: normal;\"><em><span style=\"font-size: 14px;color: rgb(136, 136, 136);\">\u6587\u7ae0\u6765\u6e90\uff1a\u884c\u821fDrug\uff0c\u836f\u7814\u7f16\u8f91\u6574\u7406<\/span><\/em><\/p>\n<p style=\"white-space: normal;\"><br  \/><\/p>\n<p style=\"text-align: center;\">\n<p><br  \/><\/p>\n<\/p><\/div>\n","protected":false},"excerpt":{"rendered":"<p>\u5bf9\u4e8eCAR-T\u7ec6\u80de\u7597\u6cd5\u6765\u8bf4\uff0c2017\u5e74\u662f\u5177\u6709\u91cc\u7a0b\u7891\u610f\u4e49\u7684\u5e74\u4efd\u30022017\u5e748\u670831\u65e5\uff0cFDA\u6279\u51c6\u9996\u4e2aCAR-T\u7597 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