{"id":40440,"date":"2018-09-10T01:00:00","date_gmt":"2018-09-17T06:42:05","guid":{"rendered":"http:\/\/www.05921.net\/index.php\/2018\/09\/17\/2018%e4%b8%8b%e5%8d%8a%e5%b9%b4%e6%9c%89%e6%9c%9b%e5%9c%a8%e5%9b%bd%e5%86%85%e4%b8%8a%e5%b8%82%e7%9a%84%e9%87%8d%e7%a3%85%e6%8a%97%e7%99%8c%e6%96%b0%e8%8d%af\/"},"modified":"2018-09-17T14:42:07","modified_gmt":"2018-09-17T06:42:07","slug":"2018%e4%b8%8b%e5%8d%8a%e5%b9%b4%e6%9c%89%e6%9c%9b%e5%9c%a8%e5%9b%bd%e5%86%85%e4%b8%8a%e5%b8%82%e7%9a%84%e9%87%8d%e7%a3%85%e6%8a%97%e7%99%8c%e6%96%b0%e8%8d%af","status":"publish","type":"post","link":"https:\/\/www.05921.net\/index.php\/40440\/","title":{"rendered":"2018\u4e0b\u534a\u5e74\u6709\u671b\u5728\u56fd\u5185\u4e0a\u5e02\u7684\u91cd\u78c5\u6297\u764c\u65b0\u836f"},"content":{"rendered":"
\n
\n
\n
\n

\u544b\u55b9\u66ff\u5c3c\u80f6\u56ca\u4e0a\u5e02\uff0c\u5c06\u7ed9\u8f6c\u79fb\u6027\u7ed3\u76f4\u80a0\u764c\u60a3\u8005\u5e26\u6765\u65b0\u7684\u6cbb\u7597\u9014\u5f84\u3002<\/span><\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n

\n
\n
\n
\n
\n

 \u5168\u65872374\u5b57\uff0c\u7528\u65f65\u5206\u949f<\/span><\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

\u4f5c\u8005\uff1a\u6cf0\u857e\u838e<\/p>\n

\u8fd1\u65e5\uff0c\u56fd\u5bb6\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40\u6279\u51c6\u544b\u55b9\u66ff\u5c3c\u80f6\u56ca\u4e0a\u5e02\uff0c\u5c06\u7ed9\u8f6c\u79fb\u6027\u7ed3\u76f4\u80a0\u764c\u60a3\u8005\u5e26\u6765\u65b0\u7684\u6cbb\u7597\u9014\u5f84\u3002\u665a\u671f\u7ed3\u76f4\u80a0\u764c\u7684\u6cbb\u7597\u8fd8\u662f\u4ee5\u5316\u7597\u4e3a\u4e3b\uff0c\u591a\u4f7f\u7528\u8054\u5408\u5316\u7597\u65b9\u6848\u3002\u4e00\u7ebf\u6cbb\u7597\u5931\u8d25\u7684\u7ed3\u76f4\u80a0\u764c\u60a3\u8005\u4ee5\u4e8c\u7ebf\u5316\u7597\u4e3a\u4e3b\uff0c\u4f46\u5f53\u524d\u4e8c\u7ebf\u6807\u51c6\u6cbb\u7597\u5931\u8d25\u540e\u7684\u60a3\u8005\u7684\u540e\u7eed\u6cbb\u7597\u65b9\u6848\u4ecd\u7136\u532e\u4e4f\u3002\u544b\u55b9\u66ff\u5c3c\u662f\u4e00\u79cd\u9ad8\u9009\u62e9\u6027\u7684VEGFR\u957f\u6548\u6291\u5236\u5242,\u9002\u5e94\u75c7\u5305\u62ec\u7ed3\u76f4\u80a0\u764c\u53ca\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\uff0c\u5b83\u7684\u51fa\u73b0\u53ef\u4ee5\u8bf4\u662f\u6253\u7834\u4e86\u665a\u671f\u7ed3\u76f4\u80a0\u764c\u5316\u7597\u4e3a\u4e3b\u7684\u5c40\u9762\uff0c\u53ef\u80fd\u7ed9\u665a\u671f\u7ed3\u76f4\u80a0\u764c\u7684\u751f\u5b58\u671f\u5e26\u6765\u65b0\u7684\u83b7\u76ca\u3002\u65e0\u8bba\u65e2\u5f80\u662f\u5426\u63a5\u53d7\u8fc7\u6297VEGF\u6216\u6297EGFR\u6cbb\u7597\uff0c\u544b\u55b9\u66ff\u5c3c\u7ec4\u5747\u80fd\u663e\u8457\u83b7\u76ca\u3002\u540c\u65f6\uff0c\u544b\u55b9\u66ff\u5c3c\u7684\u5b89\u5168\u6027\u826f\u597d\u3002\u603b\u4e4b\uff0c\u544b\u55b9\u66ff\u5c3c\u53ef\u4ee5\u6210\u4e3a\u4e09\u7ebf\u6cbb\u7597\u665a\u671f\u7ed3\u76f4\u80a0\u764c\u7684\u6807\u51c6\u6cbb\u7597\u4e4b\u4e00\u3002<\/span><\/p>\n

\u81ea2014\u5e74\u5e95\u6211\u56fd\u9996\u4e2a\u5b8c\u5168\u81ea\u4e3b\u7814\u53d1\u7684\u6297\u764c\u65b0\u836f\u963f\u5e15\u66ff\u5c3c\u4e0a\u5e02\u540e\uff0c\u56fd\u5185\u6297\u764c\u65b0\u836f\u53d1\u5c55\u5448\u9010\u5e74\u4e0a\u5347\u7684\u8d8b\u52bf\uff0c\u6d8c\u73b0\u51fa\u4e86\u975e\u5e38\u591a\u7684\u65b0\u836f\uff0c\u4ece\u5e38\u89c4\u7684\u5316\u7597\uff0c\u5230\u9010\u6b65\u7cbe\u51c6\u6cbb\u7597\u4e0b\u7684\u9776\u5411\u6cbb\u7597\uff0c\u518d\u5230\u76ee\u524d\u6700\u524d\u6cbf\u7684\u514d\u75ab\u6cbb\u7597\uff0c\u665a\u671f\u764c\u75c7\u60a3\u8005\u9762\u4e34\u66f4\u591a\u9009\u62e9\u3002<\/span>\u4e2d\u56fd\u533b\u836f\u5de5\u4e1a\u4fe1\u606f\u4e2d\u5fc3\u6839\u636e\u76f8\u5173\u6570\u636e\uff0c\u68b3\u7406\u4e86\u56fd\u5185\u65b0\u836f\u7814\u53d1\u81f3\u4e0a\u5e02\u9636\u6bb5\u7533\u8bf7\u5ba1\u6279\u5e38\u89c4\u6d41\u7a0b\uff0c\u5982\u4e0b\u8868\uff1a<\/span><\/p>\n

\u88681.\u56fd\u5185\u65b0\u836f\u7814\u53d1\u81f3\u4e0a\u5e02\u9636\u6bb5\u6ce8\u518c\u5ba1\u6279\u5e38\u89c4\u6d41\u7a0b<\/span><\/p>\n

\"2018\u4e0b\u534a\u5e74\u6709\u671b\u5728\u56fd\u5185\u4e0a\u5e02\u7684\u91cd\u78c5\u6297\u764c\u65b0\u836f\"<\/p>\n

\u6570\u636e\u6765\u6e90\uff1a\u4e2d\u56fd\u533b\u836f\u5de5\u4e1a\u4fe1\u606f\u4e2d\u5fc3\u68b3\u7406<\/span><\/p>\n

CDE\u4ece2017\u5e74\u5f00\u59cb\u52a0\u5feb\u4e86\u91cd\u5927\u65b0\u836f\u7684\u4e0a\u5e02\u5ba1\u6279\u901f\u5ea6\uff0c\u4ece\u65b0\u836f\u4e0a\u5e02\u7533\u8bf7\u53d7\u7406\u5230\u836f\u54c1\u6b63\u5f0f\u4e0a\u5e02\u5927\u7ea6\u9700\u89811\u5e74\u5de6\u53f3\uff0c\u6216\u8005\u66f4\u77ed\u7684\u65f6\u95f4\u3002\u57fa\u4e8eCDE\u7684\u516c\u5f00\u4fe1\u606f\u53ca\u4e2d\u56fd\u65b0\u836f\u7814\u53d1\u76d1\u6d4b\u6570\u636e\u5e93CPM<\/em><\/strong>\uff0c\u6211\u4eec\u9884\u6d4b\u672a\u6765\u534a\u5e74\u4ee5\u4e0b\u8fd9\u4e9b\u6297\u764c\u836f\u6781\u53ef\u80fd\u5728\u4e2d\u56fd\u4e0a\u5e02\uff0c\u6cbb\u7597\u8303\u56f4\u6db5\u76d6\u80a0\u764c\u3001\u809d\u764c\u3001\u4e73\u817a\u764c\u3001\u6dcb\u5df4\u7624\u7b49\u5e38\u89c1\u764c\u79cd\u3002<\/span><\/p>\n

\u88682.\u56fd\u5185\u5373\u5c06\u4e0a\u5e02\u6297\u764c\u91cd\u78c5\u65b0\u836f<\/span><\/p>\n

\"2018\u4e0b\u534a\u5e74\u6709\u671b\u5728\u56fd\u5185\u4e0a\u5e02\u7684\u91cd\u78c5\u6297\u764c\u65b0\u836f\"<\/p>\n

\u6570\u636e\u6765\u6e90\uff1a\u4e2d\u56fd\u533b\u836f\u5de5\u4e1a\u4fe1\u606f\u4e2d\u5fc3 \u4e2d\u56fd\u65b0\u836f\u7814\u53d1\u76d1\u6d4b\u6570\u636e\u5e93CPM<\/span><\/p>\n

2018<\/strong>\u5e74\u622a\u81f3\u76ee\u524d\u56fd\u5185\u4e0a\u5e02\u53ca\u5373\u5c06\u4e0a\u5e02\u6297\u80bf\u7624\u9776\u5411\u6cbb\u7597\u836f\u7269<\/strong><\/span><\/p>\n

2018\u5e74\u622a\u6b62\u76ee\u524d\u56fd\u5185\u4e0a\u5e02\u7684\u9776\u5411\u6cbb\u7597\u836f\u7269\u5305\u62ec\u4e86\u6cbb\u7597\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u7684\u76d0\u9178\u5b89\u7f57\u66ff\u5c3c\u3001\u5168\u7403\u9996\u4e2a\u5375\u5de2\u764cPARP\u6291\u5236\u5242\u5965\u62c9\u5e15\u5c3c\u3001\u6211\u56fd\u81ea\u4e3b\u7814\u53d1\u7684\u4e73\u817a\u764c1.1\u7c7bEGFR\/HER2\u6291\u5236\u5242\u9a6c\u6765\u9178\u5421\u54af\u66ff\u5c3c\u7247\u4ee5\u53ca\u521a\u521a\u83b7\u6279\u7684\u8f6c\u79fb\u6027\u7ed3\u76f4\u80a0\u764c\u6cbb\u7597\u836f\u7269\u544b\u55b9\u66ff\u5c3c\u80f6\u56ca\u3002\u9664\u6b64\u4e4b\u5916\uff0c\u4ee5\u4e0b\u91cd\u78c5\u65b0\u836f\u4e5f\u5907\u53d7\u5173\u6ce8\u3002<\/span><\/p>\n

\u4ed1\u4f10\u66ff\u5c3c<\/strong><\/span><\/p>\n

2017\u5e7411\u67083\u65e5\uff0c\u7532\u78fa\u9178\u4ed1\u4f10\u66ff\u5c3c\u80f6\u56ca\u6cbb\u7597\u809d\u7ec6\u80de\u764c<\/strong>\u7684\u4e0a\u5e02\u7533\u8bf7\u83b7\u5f97CDE\u627f\u529e\u53d7\u7406\uff0c2017\u5e7412\u6708\u88abCDE\u7eb3\u5165\u4f18\u5148\u5ba1\u8bc4\uff0c\u76ee\u524d\u5df2\u5230CFDA\u5ba1\u6279\u9636\u6bb5\u3002<\/span><\/p>\n

\"2018\u4e0b\u534a\u5e74\u6709\u671b\u5728\u56fd\u5185\u4e0a\u5e02\u7684\u91cd\u78c5\u6297\u764c\u65b0\u836f\"<\/p>\n

\u4ed1\u4f10\u66ff\u5c3c\u662f\u536b\u6750\u682a\u5f0f\u4f1a\u793e\u81ea\u4e3b\u7814\u53d1\u7684\u591a\u9776\u70b9\u53d7\u4f53\u916a\u6c28\u9178\u6fc0\u9176\u6291\u5236\u5242\uff0c\u5df2\u4e8e2015\u5e74\u83b7\u7f8e\u56fdFDA\u548c\u6b27\u6d32EMA\u7ba1\u7406\u5c40\u6279\u51c6\u7528\u4e8e\u4fb5\u88ad\u6027\u3001\u5c40\u90e8\u665a\u671f\u6216\u8f6c\u79fb\u6027\u5206\u5316\u578b\u7532\u72b6\u817a\u764c\u7684\u6cbb\u7597, \u5e76\u4e8e2016\u5e74FDA\u548cEMA\u76f8\u7ee7\u6279\u51c6\u4ed1\u4f10\u66ff\u5c3c\u8054\u5408\u4f9d\u7ef4\u83ab\u53f8\u6cbb\u7597\u665a\u671f\u80be\u7ec6\u80de\u764c\u3002<\/span><\/p>\n

\u5728\u4eca\u5e74ASCO\u5e74\u4f1a\u4e0a\uff0c\u91cd\u78c5\u516c\u5e03\u7684\u7814\u7a76\u7ed3\u679c\u663e\u793a\uff0c\u4ed1\u4f10\u66ff\u5c3c\u7ec4\u603b\u751f\u5b58\u671f\u975e\u52a3\u6548\u4e8e\u7d22\u62c9\u975e\u5c3c\uff0813.6\u4e2a\u6708 vs. 12.3\u4e2a\u6708\uff09\uff0c\u8fbe\u5230\u7814\u7a76\u7684\u4e3b\u8981\u7ec8\u70b9\u3002<\/span><\/p>\n

\u5e15\u59a5\u73e0\u5355\u6297<\/strong><\/span><\/p>\n

2018\u5e741\u67082\u65e5\uff0c\u91cd\u78c5\u4e73\u817a\u764c<\/strong>\u836f\u7269\u5e15\u59a5\u73e0\u5355\u6297\u5728\u4e2d\u56fd\u7684\u4e0a\u5e02\u7533\u8bf7\u83b7\u5f97CDE\u627f\u529e\u53d7\u7406\uff0c\u5e76\u4e14\u5df2\u7ecf\u83b7\u5f97CFDA\u4f18\u5148\u5ba1\u6279\u7684\u8d44\u683c\uff0c\u76ee\u524d\u5df2\u5230\u4e86\u836f\u5b66\u7814\u7a76\u7684\u5ba1\u8bc4\u9636\u6bb5\u3002<\/span><\/p>\n

\"2018\u4e0b\u534a\u5e74\u6709\u671b\u5728\u56fd\u5185\u4e0a\u5e02\u7684\u91cd\u78c5\u6297\u764c\u65b0\u836f\"<\/p>\n

\u5e15\u59a5\u73e0\u5355\u6297\u6700\u65e9\u4e8e2012\u5e746\u6708\uff0c\u5728\u7f8e\u56fd\u4e0a\u5e02\uff0c\u76ee\u524d\u5df2\u7ecf\u6210\u4e3aHER2\u6269\u589e\u9633\u6027\u7684\u4e73\u817a\u764c\u60a3\u8005\u3001\u5168\u7597\u7a0b\u7684\u7528\u836f\u9009\u62e9\uff08\u672f\u524d\u65b0\u8f85\u52a9\u53ef\u4ee5\u7528\uff0c\u672f\u540e\u8f85\u52a9\u6cbb\u7597\u53ef\u4ee5\u7528\uff0c\u665a\u671f\u6cbb\u7597\u4e5f\u53ef\u4ee5\u7528\uff09\u3002<\/span><\/p>\n

\u5e15\u59a5\u73e0\u5355\u6297\u8054\u5408\u8d6b\u8d5b\u6c40\u8054\u5408\u5316\u7597\uff0c\u76f8\u6bd4\u4e8e\u8d6b\u8d5b\u6c40\u8054\u5408\u5316\u7597\uff0c\u53ef\u4ee5\u660e\u663e\u63d0\u9ad8\u6709\u6548\u7387\u3001\u5ef6\u957f\u751f\u5b58\u671f\u3002\u4e00\u9879\u5e15\u59a5\u73e0\u5355\u6297+\u8d6b\u8d5b\u6c40+\u591a\u897f\u4ed6\u8d5b\u6cbb\u7597\u7684\u4e09\u671f\u4e34\u5e8a\u8bd5\u9a8c\u7814\u7a76\u7ed3\u679c\u8868\u660e\uff0c\u4e2d\u4f4d\u603b\u751f\u5b58\u671f\uff0c\u5e15\u59a5\u73e0\u7ec4\u662f56.5\u4e2a\u6708\uff0c\u800c\u5bf9\u7167\u7ec4\u53ea\u670940.8\u4e2a\u6708\uff0c\u76f8\u5dee15.7\u4e2a\u6708\u3002\u4e00\u4e2a\u836f\u7269\u7684\u52a0\u5165\uff0c\u8ba9\u665a\u671f\u4e73\u817a\u764c\u60a3\u8005\u603b\u751f\u5b58\u671f\u5e73\u5747\u5ef6\u957f\u4e861\u5e74\u591a\uff0c\u582a\u79f0\u5212\u65f6\u4ee3\u7684\u201c\u5947\u8ff9\u201d\u3002<\/span><\/p>\n

\u66f2\u59a5\u73e0\u5355\u6297+\u5e15\u59a5\u73e0\u5355\u6297+\u5316\u7597\u5df2\u88ab\u5168\u7403\u8d85\u8fc775\u4e2a\u56fd\u5bb6\u6279\u51c6\u7528\u4e8eHER2\u9633\u6027\u4e73\u817a\u764c\u7684\u65b0\u8f85\u52a9\u6cbb\u7597\uff0c\u6210\u4e3aHER2\u9633\u6027\u4e73\u817a\u764c\u60a3\u8005\u7684\u6807\u51c6\u6cbb\u7597\u3002<\/span><\/p>\n

\u76ee\u524d\u56fd\u5185\u4e0a\u5e02\u53ca\u5373\u5c06\u4e0a\u5e02\u6297\u80bf\u7624\u514d\u75ab\u6cbb\u7597\u836f\u7269<\/strong><\/span><\/p>\n

PD-1\u5355\u6297Opdivo\uff08\u7eb3\u6b66\u5229\u5c24\u5355\u6297\uff09\u7684\u4e0a\u5e02\u9500\u552e\u7533\u8bf7\u83b7\u5f97CDE\u627f\u529e\u53d7\u7406\u3002\u8fd9\u4f7f\u5f97Opdivo\u6210\u4e3a\u7b2c\u4e00\u6b3e\u5728\u4e2d\u56fd\u4e0a\u5e02\u7684PD-1\/PD-L1\u7c7b\u836f\u7269\u3002\u4fe1\u8fea\u5229\u5355\u6297\u662f\u7ee7Opdivo\u4e4b\u540e\u7b2c2\u4e2a\u7533\u8bf7\u4e2d\u56fd\u4e0a\u5e02\u7684PD-1\/PD-L1\u836f\u7269\uff0c\u4e5f\u662f\u9996\u4e2a\u56fd\u4ea7PD-1\u5355\u6297\u7533\u8bf7\u3002<\/span><\/p>\n

\u4fe1\u8fea\u5229\u5355\u6297<\/strong><\/span><\/p>\n

2017\u5e7412\u670813\u65e5\uff0c\u56fd\u5bb6\u836f\u76d1\u5c40\u53d7\u7406\u4e86\u4fe1\u8fbe\u751f\u7269\u56fd\u4ea7PD-1\u6291\u5236\u5242\u2014\u2014\u4fe1\u8fea\u5355\u6297\u6ce8\u5c04\u6db2\u7684\u4e0a\u5e02\u7533\u8bf7\u3002\u5982\u679c\u987a\u5229\u83b7\u6279\uff0c\u8fd9\u5c06\u6210\u4e3a\u6211\u56fd\u7b2c\u4e00\u4e2a\u4e0a\u5e02\u7684\u56fd\u4ea7PD-1\u6291\u5236\u5242\u3002\u5176\u4e5f\u662f\u7ee7Opdivo\u4e4b\u540e\u7b2c2\u4e2a\u7533\u8bf7\u4e2d\u56fd\u4e0a\u5e02\u7684PD-1\/PD-L1\u836f\u7269\u3002\u76ee\u524d\u91cd\u65b0\u9012\u4ea4\u4e86\u540e\u8fdb\u5165CFDA\u5ba1\u8bc4\u9636\u6bb5\u3002 <\/span><\/p>\n

\"2018\u4e0b\u534a\u5e74\u6709\u671b\u5728\u56fd\u5185\u4e0a\u5e02\u7684\u91cd\u78c5\u6297\u764c\u65b0\u836f\"<\/p>\n

\u4fe1\u8fea\u5355\u6297\u6ce8\u5c04\u6db2\u4ee3\u53f7IBI308\uff0c\u7533\u8bf7\u9002\u5e94\u75c7\u4e3a\u970d\u5947\u91d1\u6dcb\u5df4\u7624<\/strong>\u3002\u9664\u6b64\u9002\u5e94\u75c7\u4e4b\u5916\uff0cIBI308\u8fd8\u5728\u8fdb\u884c\u975e\u5c0f\u7ec6\u80de\u80ba\u764c \u3001\u98df\u7ba1\u764c\u4ee5\u53caNK\/T\u7ec6\u80de\u6dcb\u5df4\u7624\u4e34\u5e8a\u7814\u7a76\uff0c\u4e3b\u8981\u7528\u4e8e\u6cbb\u7597\u665a\u671f\u5b9e\u4f53\u7624\u3002<\/span><\/p>\n

\u5c0f\u5206\u5b50\u9776\u5411\u6297\u80bf\u7624\u836f\u56fd\u5185\u5e03\u5c40\u4ecd\u4ee5\u56fd\u9645\u5de8\u5934\u4e3a\u4e3b<\/strong><\/span><\/p>\n

\u6839\u636e\u4e2d\u56fd\u533b\u836f\u5de5\u4e1a\u4fe1\u606f\u4e2d\u5fc3<\/em><\/strong>\u6570\u636e\u7edf\u8ba1\uff0cSFDA\u5171\u6279\u51c6\u4e8620\u591a\u79cd\u9776\u5411\u6297\u80bf\u7624\u836f\u7269\uff0c\u5176\u4e2d80%\u4ee5\u4e0a\u4e3a\u539f\u7814\u8fdb\u53e3\u65b0\u836f\uff0c\u4e14\u591a\u4e3a\u5c0f\u5206\u5b50\u836f\u7269\uff1b\u4ec54\u79cd\u836f\u7269\u4e3a\u4e2d\u56fd\u836f\u4f01\u5f00\u53d1\u7684\u65b0\u836f\uff1a\u5176\u4e2d\u5c3c\u59a5\u73e0\u5355\u6297\u662f\u6211\u56fd\u7b2c\u4e00\u4e2a\u7528\u4e8e\u6cbb\u7597\u6076\u6027\u80bf\u7624\u7684\u529f\u80fd\u6027\u5355\u6297\u836f\u7269\uff1b\u57c3\u514b\u66ff\u5c3c\u662f\u6211\u56fd\u7b2c\u4e00\u4e2a\u62e5\u6709\u5b8c\u5168\u81ea\u4e3b\u77e5\u8bc6\u4ea7\u6743\u7684\u5c0f\u5206\u5b50\u9776\u5411\u6297\u80bf\u7624\u836f\u7269\uff1b\u53e6\u5916\uff0c\u6052\u745e\u533b\u836f\u7684\u963f\u5e15\u66ff\u5c3c\u662f\u5168\u7403\u9996\u4e2a\u88ab\u8bc1\u5b9e\u5728\u665a\u671f\u80c3\u764c\u6807\u51c6\u5316\u7597\u5931\u8d25\u540e\u5b89\u5168\u6709\u6548\u7684\u5c0f\u5206\u5b50\u6297VEGFR-2\u9776\u5411\u836f\u7269\uff1b\u5fae\u82af\u751f\u7269\u7684\u897f\u8fbe\u672c\u80fa\u662f\u5168\u7403\u9996\u4e2a\u83b7\u6279\u7684\u7ec4\u86cb\u767d\u53bb\u4e59\u9170\u5316\u9176\u6291\u5236\u5242\uff0c\u4e5f\u662f\u4e2d\u56fd\u9996\u4e2a\u6388\u6743\u7f8e\u56fd\u7b49\u53d1\u8fbe\u56fd\u5bb6\u4e13\u5229\u4f7f\u7528\u7684\u539f\u521b\u65b0\u836f\uff0c\u7528\u4e8e\u6cbb\u7597\u590d\u53d1\u6027\u6216\u96be\u6cbb\u6027\u5916\u5468T\u7ec6\u80de\u6dcb\u5df4\u7624\u3002\u6574\u4f53\u800c\u8a00\uff0c\u76ee\u524d2018\u5e74\u56fd\u5185\u7533\u8bf7\u4e0a\u5e02\u7684\u6297\u80bf\u7624\u9776\u5411\u5c0f\u5206\u5b50\u836f\u7269\u7684\u4f01\u4e1a\u4ee5\u7f57\u6c0f\u72ec\u5927\u3002<\/span><\/p>\n

\u88683.\u622a\u6b62\u76ee\u524d2018\u5e74\u56fd\u5185\u6279\u51c6\u7684\u6297\u80bf\u7624\u836f\u9776\u5411\u5c0f\u5206\u5b50<\/span><\/p>\n

\"2018\u4e0b\u534a\u5e74\u6709\u671b\u5728\u56fd\u5185\u4e0a\u5e02\u7684\u91cd\u78c5\u6297\u764c\u65b0\u836f\"<\/p>\n

\u6570\u636e\u6765\u6e90\uff1a\u4e2d\u56fd\u533b\u836f\u5de5\u4e1a\u4fe1\u606f\u4e2d\u5fc3 \u4e2d\u56fd\u65b0\u836f\u7814\u53d1\u76d1\u6d4b\u6570\u636e\u5e93CPM<\/span><\/p>\n

\u4e2d\u56fd\u7684\u514d\u75ab\u7597\u6cd5\u7684\u65b0\u683c\u5c40\u8f6c\u53d8\u5e26\u6765\u4f17\u591a\u673a\u9047\u548c\u6311\u6218<\/strong><\/span><\/p>\n

\u8fd1\u5e74\u6765\u764c\u75c7\u514d\u75ab\u7597\u6cd5\u5907\u53d7\u77a9\u76ee\uff0c\u7531\u4e8e\u76f8\u5173\u7814\u7a76\u4e0d\u65ad\u6df1\u5165\uff0cPD-1\u6291\u5236\u5242\u9010\u6e10\u5c55\u73b0\u51fa\u5728\u764c\u75c7\u6cbb\u7597\u4e0a\u7684\u6f5c\u529b\u3002\u795e\u5947\u836f\u7269\u5e15\u535a\u5229\u73e0\u5355\u6297\u66f4\u662f\u6709\u7f8e\u56fd\u5361\u7279\u603b\u7edf\u7684\u201c\u80cc\u4e66\u201d\u3002 PD-1\u6291\u5236\u5242\u65e8\u5728\u901a\u8fc7\u4eba\u4f53\u81ea\u8eab\u7684\u514d\u75ab\u7cfb\u7edf\u6297\u51fb\u80bf\u7624\uff0c\u5177\u6709\u591a\u79cd\u80bf\u7624\u7684\u9002\u5e94\u75c7\uff0c\u6709\u671b\u5b9e\u8d28\u6027\u7684\u6539\u5584\u60a3\u8005\u751f\u5b58\u671f\u3002<\/span><\/p>\n

\u83b7\u6279\u7684\u5e15\u535a\u5229\u73e0\u5355\u6297\u5c31\u662f\u6211\u4eec\u5e38\u8bf4\u7684PD-1\u6291\u5236\u5242K\u836f\uff0c\u4f5c\u4e3a\u514d\u75ab\u6cbb\u7597\u7684\u91cd\u78c5\u836f\u7269\uff0c\u5e15\u535a\u5229\u73e0\u5355\u6297\u6b64\u6b21\u5728\u56fd\u5185\u53ea\u83b7\u6279\u6cbb\u7597\u665a\u671f\u9ed1\u8272\u7d20\u7624\u60a3\u8005\uff0c\u7136\u800c\u5728\u56fd\u9645\u4e0a\uff0c\u5e15\u535a\u5229\u73e0\u5355\u6297\u76ee\u524d\u62e5\u6709\u6700\u5e7f\u6cdb\u7684\u9002\u5e94\u75c7\uff0c\u540c\u65f6\u4e5f\u662f\u5168\u7403\u7b2c\u4e00\u6b3e\u5e7f\u8c31\u6297\u764c\u836f\u7269\u3002<\/span><\/p>\n

\u9ed8\u6c99\u4e1c\u7684\u5e15\u535a\u5229\u73e0\u5355\u6297\u5728\u4e2d\u56fd\u4e0a\u5e02\u65f6\u95f4\u6bd4Opdivo\u665a\u4e861\u4e2a\u591a\u6708\uff0c\u4f46\u4e24\u8005\u9002\u5e94\u75c7\u6709\u6240\u4e0d\u540c\u3002\u56fd\u5185\u6279\u51c6\u7684Opdivo\u7528\u4e8e\u4e8c\u7ebf\u6cbb\u7597\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\uff0c\u53ef\u745e\u8fbe\u5219\u7528\u4e8e\u4e00\u7ebf\u6cbb\u7597\u540e\u53d1\u751f\u8fdb\u5c55\u7684\u5c40\u90e8\u665a\u671f\u6216\u8f6c\u79fb\u6027\u9ed1\u8272\u7d20\u7624\u3002<\/span><\/p>\n

\u4e2d\u56fd\u7684\u514d\u75ab\u6cbb\u7597\u65b0\u65f6\u4ee3\u5373\u5c06\u5f00\u542f\uff0c\u540c\u65f6\uff0cFDA\u5bf9\u521b\u65b0\u836f\u3001\u7a81\u7834\u6027\u836f\u7269\u53ca\u7f55\u89c1\u75c5\u836f\u7269\u91c7\u53d6\u52a0\u901f\u5ba1\u6279\u653f\u7b56\u4e5f\u5feb\u901f\u63a8\u52a8\u4e34\u5e8a\u6025\u9700\u7684\u521b\u65b0\u836f\u7269\u4e0a\u5e02\u3002\u653f\u7b56\u7ea2\u5229\u4e0b\uff0c\u8c01\u5c06\u4e3b\u5bb0\u80bf\u7624\u672a\u6765\u5e02\u573a\uff1f<\/span><\/p>\n

\"2018\u4e0b\u534a\u5e74\u6709\u671b\u5728\u56fd\u5185\u4e0a\u5e02\u7684\u91cd\u78c5\u6297\u764c\u65b0\u836f\"<\/p>\n

\n


<\/p>\n<\/p><\/div>\n","protected":false},"excerpt":{"rendered":"

\u544b\u55b9\u66ff\u5c3c\u80f6\u56ca\u4e0a\u5e02\uff0c\u5c06\u7ed9\u8f6c\u79fb\u6027\u7ed3\u76f4\u80a0\u764c\u60a3\u8005\u5e26\u6765\u65b0\u7684\u6cbb\u7597\u9014\u5f84\u3002  \u5168\u65872374\u5b57\uff0c\u7528\u65f65\u5206\u949f \u4f5c\u8005\uff1a\u6cf0\u857e […]<\/p>\n","protected":false},"author":1,"featured_media":40441,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[2],"tags":[],"_links":{"self":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/40440"}],"collection":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/comments?post=40440"}],"version-history":[{"count":1,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/40440\/revisions"}],"predecessor-version":[{"id":40449,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/40440\/revisions\/40449"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/media\/40441"}],"wp:attachment":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/media?parent=40440"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/categories?post=40440"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/tags?post=40440"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}