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18px;\">\u8212\u5c3c\u66ff\u5c3c\u662f\u53e3\u670d\u591a\u9776\u70b9TKI\uff0c\u5177\u6709\u53cc\u91cd\u6297\u80bf\u7624\u4f5c\u7528\u3002FDA\u4e8e2006\u5e74\u6279\u51c6\u5176\u7528\u4e8emRCC\u7684\u6cbb\u7597\uff0c2007\u5e74\u8c41\u514d\u4e34\u5e8a\u8bd5\u9a8c\u5728\u56fd\u5185\u4e0a\u5e02\u30022017\u5e74\u5168\u7403\u5e02\u573a\u9500\u552e\u989d\u8d85\u8fc710\u4ebf\u7f8e\u5143\uff0c\u5728\u56fd\u5185\u5e02\u573a\u4e5f\u8d85\u8fc72\u4ebf\u5143\u3002\u4e13\u5229\u5230\u671f\u65f6\u95f4\u57282021\u5e74\u524d\u540e\uff0c\u56fd\u5185\u6709\u9f50\u9c81\u5236\u836f\u7b49\u4f01\u4e1a\u7533\u62a5\u3002<\/span><\/p>\n<p><span style=\"font-size: 18px;\"><br  \/><\/span><\/p>\n<p><span style=\"font-size: 18px;\">\u8212\u5c3c\u66ff\u5c3c\u5168\u56fd\u5e73\u5747\u4ef7\u683c\u572813100\u5143\/\u76d2\u5de6\u53f3\uff0c\u73b0\u5df2\u8fdb\u5165\u591a\u4e2a\u5730\u65b9\u7684\u7701\u7ea7\u533b\u4fdd\u3002\u5e76\u4e14\u6839\u636e\u60a3\u8005\u4e0d\u540c\u7684\u75be\u75c5\u79cd\u7c7b\u6709\u76f8\u5173\u6148\u5584\u8d60\u836f\u653f\u7b56\u3002\u9884\u8ba1\u4eca\u5e74\u6709\u5f88\u5927\u53ef\u80fd\u4f1a\u4e00\u4e3e\u8fdb\u5165\u56fd\u5bb6\u533b\u4fdd\u8c08\u5224\u76ee\u5f55\u3002<\/span><\/p>\n<p><span style=\"font-size: 18px;color: rgb(0, 82, 255);\"><br  \/><\/span><\/p>\n<p><span style=\"font-size: 18px;color: rgb(0, 82, 255);\">\u203b\u7532\u78fa\u9178\u5965\u5e0c\u66ff\u5c3c\u7247<\/span><\/p>\n<p><span style=\"font-size: 18px;\"><br  \/><\/span><\/p>\n<p><span style=\"font-size: 18px;\">\u5965\u5e0c\u66ff\u5c3c\u7531\u963f\u65af\u5229\u5eb7\u5f00\u53d1\uff0c\u662f\u7b2c\u4e09\u4ee3\u9776\u5411\u836f\u7269\uff0c\u4e3b\u8981\u9488\u5bf9\u7b2c\u4e00\u4ee3\u9776\u5411\u836f\u7269\u7684T790M\u8010\u836f\u7a81\u53d8\u30022015\u5e7411\u6708\uff0c\u5965\u5e0c\u66ff\u5c3c\u83b7FDA\u6279\u51c6\u5728\u7f8e\u56fd\u9996\u5148\u4e0a\u5e02\uff0c\u662f\u7f8e\u56fdFDA\u6709\u53f2\u4ee5\u6765\u4e0a\u5e02\u6700\u5feb\u7684\u6297\u764c\u836f\uff0c\u4ece\u4e34\u5e8a\u8bd5\u9a8c\u5230\u4e0a\u5e02\u8bb8\u53ef\u4ec5\u5386\u65f6\u4e24\u5e74\u534a\u3002\u76ee\u524d\u5168\u7403\u9500\u552e\u989d\u63a5\u8fd110\u4ebf\u7f8e\u5143\u3002<\/span><\/p>\n<p><span style=\"font-size: 18px;\"><br  \/><\/span><\/p>\n<p><span style=\"font-size: 18px;\">\u5728\u4e2d\u56fd\uff0c\u5965\u5e0c\u66ff\u5c3c\u8fdb\u5165\u4e86<\/span><span style=\"font-size: 18px;\">CFDA\u5feb\u901f\u5ba1\u6279\u901a\u9053\u540e\uff0c\u4ece\u53d7\u7406\uff082016\u5e749\u6708\uff09\u5230\u4e0a\u5e02\u7533\u8bf7\u6279\u51c6\uff082017\u5e743\u6708\uff09\u4ec5\u7528\u4e867\u4e2a\u6708\uff0c\u6210\u4e3a\u6211\u56fd\u65b0\u836f\u5ba1\u6279\u6539\u9769\u540e\u4e0a\u5e02\u5ba1\u6279\u65f6\u95f4\u6700\u77ed\u7684\u836f\u7269\uff0c\u4e13\u95e8\u9488\u5bf9\u7531EGFR\u57fa\u56e0\u7a81\u53d8\u5f15\u8d77\u7684\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u3002<\/span><span style=\"font-size: 18px;\">\u6b27\u7f8e\u80ba\u764c\u60a3\u8005\u4e2d<\/span><span style=\"font-size: 18px;\">EGFR\u7a81\u53d8\u4e0d\u523010%\uff0c\u800c\u4e2d\u56fd\u4e2d\u5374\u6709\u8fd130%\uff0c\u80ba\u817a\u764c\u4e2d\u66f4\u662f\u9ad8\u8fbe50%\u4ee5\u4e0a\uff01<\/span><span style=\"font-size: 18px;\">\u53ef\u89c1\u8be5\u836f\u5728\u6211\u56fd\u5e02\u573a\u7684\u91cd\u8981\u610f\u4e49\u548c\u5de8\u5927\u7684\u5e02\u573a\u7a7a\u95f4\u3002<\/span><\/p>\n<p><span style=\"font-size: 18px;\"><br  \/><\/span><\/p>\n<p><span style=\"font-size: 18px;\">\u4f46\u5965\u5e0c\u66ff\u5c3c\u6bcf\u76d2\u5e73\u5747\u8d85\u8fc7<\/span><span style=\"font-size: 18px;\">5<\/span><span style=\"font-size: 18px;\">\u4e07\u4eba\u6c11\u5e01\u7684\u552e\u4ef7\uff0c\u5bf9\u666e\u901a\u767e\u59d3\u6765\u8bf4\u662f\u4e00\u4e2a\u5929\u6587\u6570\u5b57\u3002<\/span><span style=\"font-size: 18px;\">\u540c\u65f6\uff0c\u8be5\u836f\u4e13\u5229\u5230\u671f\u65f6\u95f4\u5728<\/span><span style=\"font-size: 18px;\">2<\/span><span style=\"font-size: 18px;\">032<\/span><span style=\"font-size: 18px;\">\u5e74\uff0c<\/span><span style=\"font-size: 18px;\">\u6b64\u6b21\u533b\u4fdd\u51c6\u5165\u8c08\u5224<\/span><span style=\"font-size: 18px;\">\u538b\u529b\u6781\u5927\u3002\u5982\u8981\u8c08\u5224\u6210\u529f\uff0c<\/span><span style=\"font-size: 18px;\">\u5fc5\u5b9a\u4f1a\u5bf9\u5176\u4ef7\u683c\u4e0d\u65ad\u65bd\u538b\uff0c\u4ece\u800c\u8fbe\u5230\u533b\u4fdd\u57fa\u91d1\u627f\u53d7\u8303\u56f4\uff0c\u63d0\u9ad8\u4eba\u4eec\u7684\u7528\u836f\u53ef\u8d1f\u62c5\u6027\u3002<\/span><\/p>\n<p><span style=\"font-size: 18px;\"><br  \/><\/span><\/p>\n<p><span style=\"font-size: 18px;color: rgb(0, 82, 255);\">\u203b\u78f7\u9178\u82a6\u53ef\u66ff\u5c3c\u7247<\/span><\/p>\n<p><span style=\"font-size: 18px;\"><br  \/><\/span><\/p>\n<p><span style=\"font-size: 18px;\">\u82a6\u53ef\u66ff\u5c3c\u662f\u76ee\u524d\u552f\u4e00\u9488\u5bf9\u9aa8\u9ad3\u7ea4\u7ef4\u5316\u53d1\u75c5\u673a\u5236\u7684\u9776\u5411\u6cbb\u7597\u836f\u7269\u3002<\/span><span style=\"font-size: 18px;\">FDA\u6388\u4e88\u82a6\u53ef\u66ff\u5c3c\u6cbb\u7597\u9aa8\u9ad3\u7ea4\u7ef4\u5316\u7684\u5b64\u513f\u836f\u5730\u4f4d\uff0c\u5e76\u4e8e2011\u5e7411\u670816\u65e5\u5728\u7f8e\u56fd\u4e0a\u5e02\u3002\u8bfa\u534e\u4eceIncyte\u516c\u53f8\u6388\u6743\u83b7\u5f97\u9c81\u7d22\u5229\u66ff\u5c3c\u5728\u7f8e\u56fd\u4ee5\u5916\u7684\u5f00\u53d1\u548c\u5546\u4e1a\u5316\u6743\u5229\u3002\u82a6\u53ef\u66ff\u5c3c\u5df2\u6210\u4e3a\u6b27\u6d32\u80bf\u7624\u5185\u79d1\u5b66\u4f1a\u3001\u82f1\u56fd\u3001\u5fb7\u56fd\u3001\u7f8e\u56fd\u56fd\u5bb6\u7efc\u5408\u764c\u75c7\u7f51\u7edc\u6307\u5357\u63a8\u8350\u7684\u9aa8\u9ad3\u7ea4\u7ef4\u5316\u6cbb\u7597\u836f\u7269\uff0c\u5e76\u83b7\u5f97\u4e86\u300a\u539f\u53d1\u6027\u9aa8\u9ad3\u7ea4\u7ef4\u5316\u8bca\u65ad\u4e0e\u6cbb\u7597\u4e2d\u56fd\u4e13\u5bb6\u5171\u8bc6\u300b\uff082015\u5e74\u7248\uff09\u7684\u63a8\u8350\uff0c\u53ef\u89c1\u5176\u91cd\u8981\u6027\u3002<\/span><\/p>\n<p><span style=\"font-size: 18px;\"><br  \/><\/span><\/p>\n<p><span style=\"font-size: 18px;\">2017\u5e743\u670810\u65e5\u83b7\u5f97CFDA\u6279\u51c6\u7528\u4e8e\u4e2d\u5371\u6216\u9ad8\u5371\u7684\u539f\u53d1\u6027\u9aa8\u9ad3\u7ea4\u7ef4\u5316\u3001\u771f\u6027\u7ea2\u7ec6\u80de\u589e\u591a\u75c7\u7ee7\u53d1\u7684\u9aa8\u9ad3\u7ea4\u7ef4\u5316\u6216\u539f\u53d1\u6027\u8840\u5c0f\u677f\u589e\u591a\u75c7\u7ee7\u53d1\u7684\u9aa8\u9ad3\u7ea4\u7ef4\u5316\u7684\u6210\u5e74\u60a3\u8005\uff0c\u6cbb\u7597\u75be\u75c5\u76f8\u5173\u813e\u80bf\u5927\u6216\u75be\u75c5\u76f8\u5173\u75c7\u72b6\u3002<\/span><span style=\"font-size: 18px;\">\u76ee\u524d\u5728\u56fd\u5185\u5e02\u573a\u8fd8\u8f83\u5c0f\uff0c\u9500\u552e\u5355\u4ef7\u5728<\/span><span style=\"font-size: 18px;\">8<\/span><span style=\"font-size: 18px;\">000<\/span><span style=\"font-size: 18px;\">\u5143\u5de6\u53f3\uff0c\u5f88\u53ef\u80fd\u5728\u4eca\u5e74\u7eb3\u5165\u533b\u4fdd\u8c08\u5224\u5e76\u53d6\u5f97\u6210\u529f\u3002<\/span><\/p>\n<p><span style=\"font-size: 18px;\"><br  \/><\/span><\/p>\n<p><span style=\"font-size: 18px;color: rgb(0, 82, 255);\">\u203b\u7eb3\u6b66\u5229\u5c24\u5355\u6297\u6ce8\u5c04\u6db2<\/span><\/p>\n<p><span style=\"font-size: 18px;\"><br  \/><\/span><\/p>\n<p><span style=\"font-size: 18px;\">\u7eb3\u6b66\u5229\u5c24\u5355\u6297\u6ce8\u5c04\u6db2\u662f\u4e00\u79cd<\/span><span style=\"font-size: 18px;\">PD-1\u514d\u75ab\u68c0\u67e5\u70b9\u6291\u5236\u5242\uff0c\u72ec\u7279\u5730\u5229\u7528\u4eba\u4f53\u81ea\u8eab\u7684\u514d\u75ab\u7cfb\u7edf\u6765\u5e2e\u52a9\u673a\u4f53\u6062\u590d\u6297\u80bf\u7624\u514d\u75ab\u53cd\u5e94\u3002\u8fd9\u79cd\u901a\u8fc7\u5229\u7528\u4eba\u4f53\u81ea\u8eab\u514d\u75ab\u7cfb\u7edf\u6765\u6297\u51fb\u764c\u75c7\u7684\u7279\u6027\uff0c\u4f7f\u7eb3\u6b66\u5229\u5c24\u5355\u6297\u6ce8\u5c04\u6db2\u5df2\u6210\u4e3a\u591a\u79cd\u80bf\u7624\u7684\u91cd\u8981\u6cbb\u7597\u9009\u62e9\u3002<\/span><\/p>\n<p><span style=\"font-size: 18px;\"><br  \/><\/span><\/p>\n<p><span style=\"font-size: 18px;\">2014\u5e747\u6708\uff0c\u7eb3\u6b66\u5229\u5c24\u5355\u6297\u6ce8\u5c04\u6db2\u5728\u65e5\u672c\u4e0a\u5e02\uff0c\u6210\u4e3a\u5168\u7403\u9996\u4e2a\u83b7\u5f97\u76d1\u7ba1\u673a\u6784\u6279\u51c6\u7684PD-1\u514d\u75ab\u68c0\u67e5\u70b9\u6291\u5236\u5242\uff0c\u76ee\u524d\u83b7\u5f97\u7f8e\u56fd\u3001\u6b27\u76df\u3001\u65e5\u672c\u548c\u4e2d\u56fd\u5728\u518560\u591a\u4e2a\u56fd\u5bb6\u548c\u5730\u533a\u7684\u6279\u51c6\u3002<\/span><span style=\"font-size: 18px;\">\u7eb3\u6b66\u5229\u5c24\u5355\u6297\u6ce8\u5c04\u6db2<\/span><span style=\"font-size: 18px;\">\u4e8e<\/span><span style=\"font-size: 18px;\">2<\/span><span style=\"font-size: 18px;\">018<\/span><span style=\"font-size: 18px;\">\u5e74<\/span><span style=\"font-size: 18px;\">6\u670815\u65e5\u83b7\u5f97CFDA\u7684\u6b63\u5f0f\u6279\u51c6\uff0c\u7528\u4e8e\u4e8c\u7ebf\u6cbb\u7597\u6210\u4eba\u8868\u76ae\u751f\u957f\u56e0\u5b50\u53d7\u4f53\uff08EGFR\uff09\u57fa\u56e0\u7a81\u53d8\u9634\u6027\u548c\u95f4\u53d8\u6027\u6dcb\u5df4\u7624\u6fc0\u9176\uff08ALK\uff09\u9634\u6027\u3001\u65e2\u5f80\u63a5\u53d7\u8fc7\u542b\u94c2\u65b9\u6848\u5316\u7597\u540e\u75be\u75c5\u8fdb\u5c55\u6216\u4e0d\u53ef\u8010\u53d7\u7684\u5c40\u90e8\u665a\u671f\u6216\u8f6c\u79fb\u6027\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\uff08NSCLC\uff09\uff0c\u662f\u7b2c\u4e00\u4e2a\u5728\u4e2d\u56fd\u83b7\u6279\u7684PD-1\/PD-L1\u7c7b\u836f\u7269\u3002<\/span><\/p>\n<p><span style=\"font-size: 18px;\"><br  \/><\/span><\/p>\n<p><span style=\"font-size: 18px;\">8\u670810\u65e5\uff0c\u767e\u65f6\u7f8e\u65bd\u8d35\u5b9d\u5728\u5317\u4eac\u4e3e\u529ePD-1\u5355\u6297Opdivo\u7684\u4e2d\u56fd\u4e0a\u5e02\u5a92\u4f53\u53d1\u5e03\u4f1a\u3002\u4f1a\u4e2d\u900f\u9732\uff0cOpdivo\uff08\u7eb3\u6b66\u5229\u5c24\u5355\u6297\u6ce8\u5c04\u6db2\uff0c\u6b27\u72c4\u6c83\uff09\u5c06\u4e8e\u4eca\u5e74\u7b2c3\u5b63\u5ea6\u6b63\u5f0f\u767b\u9646\u4e2d\u56fd\u5e02\u573a\u3002<\/span><span style=\"font-size: 18px;\">\u4f46\u636e\u4f20\u8be5\u836f\u4ef7\u683c\u9ad8\u7684\u53ef\u6015\uff0c\u5728\u7f8e\u56fd\u4e00\u5e74\u7684\u6cbb\u7597\u6210\u672c\u5927\u7ea6<\/span><span style=\"font-size: 18px;\">1<\/span><span style=\"font-size: 18px;\">7<\/span><span style=\"font-size: 18px;\">\u4e07\u7f8e\u5143\uff0c\u8fd1<\/span><span style=\"font-size: 18px;\">1<\/span><span style=\"font-size: 18px;\">10<\/span><span style=\"font-size: 18px;\">\u4e07\u5143\u4eba\u6c11\u5e01\uff0c\u6708\u5747\u6cbb\u7597\u6210\u672c\u5728<\/span><span style=\"font-size: 18px;\">9\u4e07\u5143\u5de6\u53f3\uff0c\u5373\u4f7f\u5728\u4e2d\u56fd\u4ef7\u683c\u4ee5\u6b645<\/span><span style=\"font-size: 18px;\">0<\/span><span style=\"font-size: 18px;\">%\u8ba1\uff0c\u5219\u5e74\u6cbb\u7597\u6210\u672c\u8d85\u8fc75<\/span><span style=\"font-size: 18px;\">0<\/span><span style=\"font-size: 18px;\">\u4e07\u5143\u4eba\u6c11\u5e01\uff0c\u9c9c\u6709\u5bb6\u5ead\u53ef\u4ee5\u627f\u62c5\u5982\u6b64\u9ad8\u6602\u7684\u8d39\u7528\u3002\u4e13\u5229\u5230\u671f\u65f6\u95f4\u5728<\/span><span style=\"font-size: 18px;\">2<\/span><span style=\"font-size: 18px;\">026<\/span><span style=\"font-size: 18px;\">\u5e74\uff0c\u8c08\u5224\u4ef7\u683c\u538b\u529b\u5de8\u5927\u3002\u4f46\u5982\u679c\u4e0d\u901a\u8fc7\u8c08\u5224\u8fdb\u5165\u533b\u4fdd\uff0c\u8fd9\u6837\u9ad8\u6602\u7684\u6cbb\u7597\u8d39\u7528\u9884\u8ba1\u9c9c\u6709\u5bb6\u5ead\u53ef\u4ee5\u627f\u62c5\u3002<\/span><\/p>\n<p><span style=\"font-size: 18px;\"><br  \/><\/span><\/p>\n<p><span style=\"font-size: 18px;color: rgb(217, 33, 66);\">\u56fd\u4ea7\u80bf\u7624\u836f\u5c0f\u8377\u624d\u697c\u5c16\u5c16\u89d2<\/span><\/p>\n<p><span style=\"font-size: 18px;\"><br  \/><\/span><\/p>\n<p><span style=\"font-size: 18px;\">\u5728\u6211\u56fd\u80bf\u7624\u9776\u5411\u836f\u5e02\u573a\u57fa\u672c\u662f\u88ab\u8fdb\u53e3\u836f\u9738\u5360\uff0c\u4f46\u8fd1\u4e00\u4e9b\u5e74\u90e8\u5206\u56fd\u5185\u54c1\u79cd\u4e5f\u5728\u5feb\u901f\u53d1\u5c55\uff0c\u5982\u767e\u8fbe\u836f\u4e1a\u7684\u57c3\u514b\u66ff\u5c3c\uff0c\u6052\u745e\u533b\u836f\u7684\u963f\u5e15\u66ff\u5c3c\u7b49\u54c1\u79cd\u5df2\u901a\u8fc7\u533b\u4fdd\u8c08\u5224\u8fdb\u5165\u4e86\u533b\u4fdd\u76ee\u5f55\u3002\u6b64\u5916\uff0c\u8fd8\u6709\u4e00\u4e9b\u7597\u6548\u5c1a\u53ef\u3001\u4e34\u5e8a\u9700\u6c42\u8f83\u5927\u3001\u4ef7\u683c\u8f83\u9ad8\u7684\u54c1\u79cd\u5c1a\u672a\u8fdb\u5165\u533b\u4fdd\u76ee\u5f55\uff0c\u4eca\u5e74\u88ab\u7eb3\u5165\u8c08\u5224\u7684\u53ef\u80fd\u6027\u4e5f\u6bd4\u8f83\u5927\u3002<\/span><\/p>\n<p><span style=\"font-size: 18px;\"><br  \/><\/span><\/p>\n<p><span style=\"font-size: 18px;color: rgb(0, 82, 255);\">\u203b\u6ce8\u5c04\u7528\u96f7\u66ff\u66f2\u585e<\/span><\/p>\n<p><span style=\"font-size: 18px;\"><br  \/><\/span><\/p>\n<p><span style=\"font-size: 18px;\">\u96f7\u66ff\u66f2\u585e\u53c8\u540d<\/span><span style=\"font-size: 18px;\">\u5170\u66ff\u7279\u567b<\/span><span style=\"font-size: 18px;\">\uff0c<\/span><span style=\"font-size: 18px;\">\u4e3a\u6297\u4ee3\u8c22\u7c7b\u53f6\u9178\u7c7b\u4f3c\u7269\uff0c\u7279\u5f02\u6027\u5730\u6291\u5236\u80f8\u82f7\u9178\u5408\u6210\u9176\uff08<\/span><span style=\"font-size: 18px;\">TS\uff09\u3002\u4e0e5-FU\u6216\u6c28\u7532\u558b\u5464\u76f8\u6bd4\uff0c\u96f7\u66ff\u66f2\u585e\u662f\u76f4\u63a5\u7684\u548c\u7279\u5f02\u6027\u7684TS\u6291\u5236\u5242<\/span><span style=\"font-size: 18px;\">\uff0c\u4e3b\u8981\u7528\u4e8e\u665a\u671f\u7ed3\u76f4\u80a0\u764c\u60a3\u8005\u3002<\/span><\/p>\n<p><span style=\"font-size: 18px;\"><br  \/><\/span><\/p>\n<p><span style=\"font-size: 18px;\">\u96f7\u66ff\u66f2\u585e\u539f\u7814\u5382\u5bb6\u4e3a<\/span><span style=\"font-size: 18px;\">B<\/span><span style=\"font-size: 18px;\">TG I<\/span><span style=\"font-size: 18px;\">nte<\/span><span style=\"font-size: 18px;\">rnationl Ltd<\/span><span style=\"font-size: 18px;\">\uff0c<\/span><span style=\"font-size: 18px;\">2<\/span><span style=\"font-size: 18px;\">006<\/span><span style=\"font-size: 18px;\">\u5e74\u5316\u5408\u7269\u4e13\u5229\u5230\u671f\u3002\u56fd\u5185\u7684\u6b63\u5927\u5929\u6674<\/span><span style=\"font-size: 18px;\">2<\/span><span style=\"font-size: 18px;\">010<\/span><span style=\"font-size: 18px;\">\u5e74\u83b7\u5f97\u9996\u4eff\u4e0a\u5e02\uff0c\u867d\u7136\u4e0d\u662f\u5168\u7403\u65b0\u7684\u539f\u7814\u836f\uff0c\u4f46\u4e5f\u62e5\u6709<\/span><span style=\"font-size: 18px;\">\u4e00\u79cd\u542b\u6709\u96f7\u66ff\u66f2\u585e\u7684\u836f\u7269\u7ec4\u5408\u7269\u53ca\u5176\u5236\u5907\u65b9\u6cd5<\/span><span style=\"font-size: 18px;\">\u4e13\u5229\uff08\u4e13\u5229\u53f7<\/span><span style=\"font-size: 18px;\">201210119388.8<\/span><span style=\"font-size: 18px;\">\uff09\uff0c\u8be5\u5e02\u573a\u4ecd\u7531\u6b63\u5927\u5929\u6674\u72ec\u5360\u3002\u81f3<\/span><span style=\"font-size: 18px;\">2<\/span><span style=\"font-size: 18px;\">017<\/span><span style=\"font-size: 18px;\">\u5e74\u5f55\u5f97<\/span><span style=\"font-size: 18px;\">3<\/span><span style=\"font-size: 18px;\">3,387<\/span><span style=\"font-size: 18px;\">\u4e07\u5143\u4eba\u6c11\u5e01\u7684\u6536\u5165\u3002\u4e2d\u6807\u4ef7\u5728<\/span><span style=\"font-size: 18px;\">1<\/span><span style=\"font-size: 18px;\">600<\/span><span style=\"font-size: 18px;\">\u5143\u5de6\u53f3\u3002\u7eb3\u5165\u8c08\u5224\u7684\u53ef\u80fd\u6027\u5f88\u5927\u3002<\/span><\/p>\n<p><span style=\"font-size: 18px;\"><br  \/><\/span><\/p>\n<p><span style=\"font-size: 18px;color: rgb(0, 82, 255);\">\u203b\u76d0\u9178\u5b89\u7f57\u66ff\u5c3c\u80f6\u56ca<\/span><\/p>\n<p><span style=\"font-size: 18px;\"><br  \/><\/span><\/p>\n<p><span style=\"font-size: 18px;\">\u5b89\u7f57\u66ff\u5c3c\u662f\u4e00\u79cd\u65b0\u578b\u5c0f\u5206\u5b50\u591a\u9776\u70b9\u916a\u6c28\u9178\u6fc0\u9176\u6291\u5236\u5242\uff0c\u80fd\u6709\u6548\u4f5c\u7528\u4e8e<\/span><span style=\"font-size: 18px;\">VEGFR\u3001PDGFR\u3001FGFR\u3001 c-Kit\u7b49\u9776\u70b9\uff0c\u5177\u6709\u6297\u80bf\u7624\u8840\u7ba1\u751f\u6210\u548c\u6291\u5236\u80bf\u7624\u751f\u957f\u7684\u53cc\u91cd\u4f5c\u7528\u3002\u7ecf\u4e34\u5e8a\u8bd5\u9a8c\u8bc1\u5b9e\uff0c\u798f\u53ef\u7ef4\u662f\u76ee\u524d\u665a\u671f\u975e\u5c0f\u7ec6\u80de\u80ba\u764c(NSCLC)\u6297\u8840\u7ba1\u751f\u6210\u9776\u5411\u836f\u7269\u4e2d\u4ec5\u6709\u7684\u5355\u836f\u6709\u6548\u7684\u53e3\u670d\u5236\u5242\uff0c\u800c\u4e14\u4e0d\u826f\u53cd\u5e94\u8f83\u8f7b\uff0c\u60a3\u8005\u8010\u53d7\u6027\u826f\u597d\u3002<\/span><\/p>\n<p><span style=\"font-size: 18px;\"><br  \/><\/span><\/p>\n<p><span style=\"font-size: 18px;\">\u5b89\u7f57\u66ff\u5c3c\u662f<\/span><span style=\"font-size: 18px;\">\u6b63\u5927\u5929\u6674<\/span><span style=\"font-size: 18px;\">\u9996\u4e2a\u6309\u7167\u56fd\u9645\u7814\u53d1\u6d41\u7a0b\u548c<\/span><span style=\"font-size: 18px;\">\u6807\u51c6<\/span><span style=\"font-size: 18px;\">\u8fdb\u884c\u5f00\u53d1\u7684\u521b\u65b0<\/span><span style=\"font-size: 18px;\">1<\/span><span style=\"font-size: 18px;\">.1<\/span><span style=\"font-size: 18px;\">\u7c7b<\/span><span style=\"font-size: 18px;\">\u5c0f\u5206\u5b50\u836f\uff0c\u4e5f\u662f\u8be5\u96c6\u56e2\u8fc4\u4eca\u4e3a\u6b62\u7814\u53d1\u6295\u5165\u6700\u591a\u7684\u6297\u764c\u836f<\/span><span style=\"font-size: 18px;\">\uff0c\u4e8e\u4eca\u5e74<\/span><span style=\"font-size: 18px;\">5\u6708\u83b7\u5f97\u751f\u4ea7\u6279\u4ef6<\/span><span style=\"font-size: 18px;\">\u3002<\/span><span style=\"font-size: 18px;\">\u76ee\u524d\u6682\u65e0\u516c\u5f00\u7684\u4e2d\u6807\u7684\u4ef7\u683c\uff0c\u7f51\u4f20\u4ef7\u683c\u5728<\/span><span style=\"font-size: 18px;\">6<\/span><span style=\"font-size: 18px;\">000<\/span><span style=\"font-size: 18px;\">\u5143\u5de6\u53f3\uff0c\u7531\u4e8e\u662f\u65b0\u4e0a\u5e02\u54c1\u79cd\uff0c\u9884\u8ba1\u8c08\u5224\u7684\u538b\u529b\u8f83\u5927\u3002<\/span><\/p>\n<p><span style=\"font-size: 18px;\"><br  \/><\/span><\/p>\n<p><span style=\"font-size: 18px;color: rgb(0, 82, 255);\">\u203b\u6c2f\u6c27\u55b9\u80f6\u56ca<\/span><\/p>\n<p><span style=\"font-size: 18px;\"><br  \/><\/span><\/p>\n<p><span style=\"font-size: 18px;\">\u6c2f\u6c27\u55b9\u662f\u56fd\u5bb6\u7ea7\u4e00\u7c7b\u53cc\u9776\u5411\u6297\u764c\u65b0\u836f<\/span><span style=\"font-size: 18px;\">\uff0c\u53ef\u7528\u4e8e<\/span><span style=\"font-size: 18px;\">\u76f4\u80a0\u764c\u3001\u80be\u764c\u3001\u4e73\u817a\u764c\u3001\u80ba\u764c\u3001\u809d\u764c\u3001\u767d\u8840\u75c5\u3001\u7ed3\u80a0\u764c\u3001\u8180\u80f1\u764c\u3001\u80c3\u764c\u3001\u80f0\u817a\u764c\u3001\u9aa8\u8089\u7624\u3001\u6076\u6027\u6dcb\u5df4\u7624\u3001\u8111\u80bf\u7624\u7b49<\/span><span style=\"font-size: 18px;\">\u591a\u79cd\u80bf\u7624<\/span><span style=\"font-size: 18px;\">\u7684\u6cbb\u7597\u3002\u6c2f\u6c27\u55b9\u80f6\u56ca\u836f\u7269\u6210\u5206\u4e0e<\/span><span style=\"font-size: 18px;\">DNA\u4e0a\u7684\u9e1f\u560c\u5464\u6709\u4eb2\u548c\u4f5c\u7528,\u4f7f\u836f\u7269\u5d4c\u5165DNA\u4e24\u80a1\u4e4b\u95f4,\u4ece\u800c\u5f62\u6210DNA\u52a0\u5408\u7269,\u6291\u5236DNA\u529f\u80fd,\u8fbe\u5230\u963b\u6b62DNA\u590d\u5236\u3001\u8f6c\u5f55\u7684\u76ee\u7684,\u4ece\u800c\u6291\u5236\u764c\u7ec6\u80de\u3002<\/span><\/p>\n<p><span style=\"font-size: 18px;\"><br  \/><\/span><\/p>\n<p><span style=\"font-size: 18px;\">\u6c2f\u6c27\u55b9<\/span><span style=\"font-size: 18px;\">2003\u5e744\u6708\u83b7\u5f97\u56fd\u5bb6\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40\u9881\u53d1\u7684\u65b0\u836f\u8bc1\u4e66\u3002\u4ee5\u5176\u5177\u6709\u4e0e\u5355\u836f\u4f7f\u7528\u3001\u4e0e\u8054\u5408\u5316\u7597\u65b9\u6848\u76f8\u4f3c\u7684\u7597\u6548\uff0c\u5ef6\u957f\u60a3\u8005\u751f\u5b58\u671f\u53ca\u75be\u75c5\u7a33\u5b9a\u671f\uff0c\u6539\u5584\u60a3\u8005\u751f\u6d3b\u8d28\u91cf\u3002\u5f53\u524d\u67094<\/span><span style=\"font-size: 18px;\">5<\/span><span style=\"font-size: 18px;\">\u7c92\u548c<\/span><span style=\"font-size: 18px;\">6<\/span><span style=\"font-size: 18px;\">0<\/span><span style=\"font-size: 18px;\">\u7c92\u4e24\u4e2a\u5305\u88c5\u89c4\u683c\u3002<\/span><\/p>\n<p><span style=\"font-size: 18px;\"><br  \/><\/span><\/p>\n<p><span style=\"font-size: 18px;\">\u9884\u8ba1\u5e02\u573a\u9500\u552e\u4ee5<\/span><span style=\"font-size: 18px;\">6<\/span><span style=\"font-size: 18px;\">0<\/span><span style=\"font-size: 18px;\">\u7c92\u7684\u4e3a\u4e3b\uff0c\u4e0d\u540c\u7701\u4efd\u4ef7\u683c\u5dee\u5f02\u8f83\u5927\uff0c\u5728<\/span><span style=\"font-size: 18px;\">1<\/span><span style=\"font-size: 18px;\">300<\/span><span style=\"font-size: 18px;\">&#8211;<\/span><span style=\"font-size: 18px;\">2600<\/span><span style=\"font-size: 18px;\">\u5143\u4e4b\u95f4\u3002\u4e0a\u5e02\u65f6\u95f4\u5df2\u6709<\/span><span style=\"font-size: 18px;\">1<\/span><span style=\"font-size: 18px;\">5<\/span><span style=\"font-size: 18px;\">\u5e74\uff0c\u4f46\u662f\u9500\u552e\u89c4\u6a21\u4e0d\u5927\uff0c\u53ef\u89c1\u5176\u7597\u6548\u5728\u4e34\u5e8a\u5e76\u672a\u83b7\u5f97\u5e7f\u6cdb\u8ba4\u53ef\u3002\u9884\u8ba1\u4eca\u5e74\u88ab\u7eb3\u5165\u8c08\u5224\u4e5f\u662f\u6709\u4e00\u5b9a\u53ef\u80fd\u7684\u3002<\/span><\/p>\n<p><span style=\"font-size: 18px;\"><br  \/><\/span><\/p>\n<p><span style=\"font-size: 18px;\">\u6b64\u5916\uff0c\u53bb\u5e74\u8c08\u5224\u5931\u8d25\u7684\u54c1\u79cd\u4e09\u751f\u56fd\u5065\u836f\u4e1a\u7684\u91cd\u7ec4\u6297<\/span><span style=\"font-size: 18px;\">CD25\u4eba\u6e90\u5316\u5355<\/span><span style=\"font-size: 18px;\">\u514b\u9686<\/span><span style=\"font-size: 18px;\">\u6297<\/span><span style=\"font-size: 18px;\">\u4f53\uff0c\u4e3b\u8981\u7528\u4e8e\u9632\u80be\u79fb\u690d\u540e\u6025\u6027\u6392\u65a5\u53cd\u5e94\u7684\u53d1\u751f\uff0c\u4eca\u5e74\u5f88\u6709\u53ef\u80fd\u4f1a\u88ab\u518d\u6b21\u7eb3\u5165\u533b\u4fdd\u8c08\u5224\u3002<\/span><\/p>\n<p><span style=\"font-size: 18px;\"><br  \/><\/span><\/p>\n<p style=\"white-space: normal;\"><span style=\"font-size: 18px;\"><\/span><\/p>\n<p style=\"white-space: normal;\">\n<p style=\"white-space: normal;\"><span style=\"font-size: 18px;\"><\/span><\/p>\n<ul class=\"list-paddingleft-2\" style=\"list-style-type: square;\">\n<li>\n<p><a href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MjM5OTYyODk5Mg==&amp;mid=2651034239&amp;idx=2&amp;sn=a37628bde0725850a5dbdf984de6eca7&amp;chksm=bccfabd08bb822c6813b4e36d795968e9299cabb3f827b20d56703b3b5188f719c91aa206c61&amp;scene=21#wechat_redirect\" target=\"_blank\" style=\"text-decoration: underline;\"><span style=\"color: rgb(0, 82, 255);\">\u9080\u60a8\u52a0\u5165\u5168\u56fd1000\u4e2a\u533b\u836f\u7fa4<\/span><\/a><\/p>\n<\/li>\n<\/ul>\n<p style=\"white-space: normal;\"><br  \/><\/p>\n<p style=\"white-space: normal;background-color: rgb(255, 255, 255);box-sizing: border-box;color: rgb(62, 62, 62);\"><span style=\"color: rgb(136, 136, 136);font-size: 14px;\">\u672c\u5e73\u53f0\u4e0d\u5bf9\u8f6c\u8f7d\u4e4b\u6587\u7ae0\u6240\u5305\u542b\u5185\u5bb9\u7684\u51c6\u786e\u6027\u3001\u53ef\u9760\u6027\u6216\u8005\u5b8c\u6574\u6027\u63d0\u4f9b\u4efb\u4f55\u660e\u793a\u6216\u6697\u793a\u7684\u4fdd\u8bc1\uff0c\u4e0d\u5bf9\u6587\u7ae0\u89c2\u70b9\u8d1f\u8d23\u3002<\/span><\/p>\n<p style=\"white-space: normal;background-color: rgb(255, 255, 255);box-sizing: border-box;color: rgb(62, 62, 62);\"><span style=\"color: rgb(136, 136, 136);font-size: 14px;\"><br  \/><\/span><\/p>\n<p style=\"font-size: 16px;white-space: normal;color: rgb(62, 62, 62);line-height: 25.6px;font-variant-ligatures: normal;font-variant-east-asian: normal;font-variant-position: normal;word-wrap: break-word;min-height: 16px;max-width: 769px;box-sizing: border-box;orphans: 2;background-color: rgb(255, 255, 255);\"><span style=\"color: rgb(2, 30, 170);font-size: 14px;\"><span style=\"box-sizing: border-box;line-height: 25.6px;max-width: 100%;word-wrap: break-word;\">\u70b9<\/span><strong>\u9605\u8bfb\u539f\u6587<\/strong><span style=\"box-sizing: border-box;line-height: 25.6px;max-width: 100%;word-wrap: break-word;\">\u83b7\u53d6<span style=\"line-height: 25.6px;max-width: 100%;\">\u884c\u4e1a\u5927\u6570\u636e<\/span><\/span><\/span><\/p>\n<\/p><\/div>\n","protected":false},"excerpt":{"rendered":"<p>\u6765\u6e90\uff1a\u8d5b\u67cf\u84dd \u7279\u7ea6\u64b0\u7a3f\uff1a\u70e8\u534e \u65e5\u524d\uff0c\u56fd\u5bb6\u533b\u7597\u4fdd\u969c\u5c40\u76f8\u5173\u8d1f\u8d23\u4eba\u63a5\u53d7\u5a92\u4f53\u91c7\u8bbf\u65f6\u8868\u793a\uff0c\u65b0\u4e00\u8f6e\u6297\u764c\u836f\u4e13\u9879\u8c08\u5224\u7a33\u6b65\u63a8\u8fdb\uff0c 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