{"id":4393,"date":"2018-07-06T01:00:00","date_gmt":"2018-07-27T06:52:26","guid":{"rendered":"http:\/\/www.05921.net\/index.php\/2018\/07\/27\/1953-2018%ef%bc%8c%e8%82%bf%e7%98%a4%e5%85%8d%e7%96%ab%e7%96%97%e6%b3%95%e7%9a%84%e7%be%a4%e6%98%9f%e9%97%aa%e8%80%80%e6%97%b6%ef%bc%88%e4%b8%8b%e7%af%87%ef%bc%89\/"},"modified":"2018-07-27T14:52:31","modified_gmt":"2018-07-27T06:52:31","slug":"1953-2018%ef%bc%8c%e8%82%bf%e7%98%a4%e5%85%8d%e7%96%ab%e7%96%97%e6%b3%95%e7%9a%84%e7%be%a4%e6%98%9f%e9%97%aa%e8%80%80%e6%97%b6%ef%bc%88%e4%b8%8b%e7%af%87%ef%bc%89","status":"publish","type":"post","link":"https:\/\/www.05921.net\/index.php\/4393\/","title":{"rendered":"1953-2018\uff0c\u80bf\u7624\u514d\u75ab\u7597\u6cd5\u7684\u7fa4\u661f\u95ea\u8000\u65f6\uff08\u4e0b\u7bc7\uff09"},"content":{"rendered":"<div class=\"bpp-post-content\">\n<p style=\"text-align: center;\"><span style=\"max-width: 100%;\">\u70b9\u51fb\u4e0a\u65b9\u7684<\/span><span style=\"max-width: 100%;\">&nbsp;\u884c\u821fDrug&nbsp;<span style=\"max-width: 100%;color: rgb(127, 127, 127);font-size: 12px;box-sizing: border-box !important;word-wrap: break-word !important;\">\u25b2<\/span><span style=\"max-width: 100%;color: rgb(127, 127, 127);box-sizing: border-box !important;word-wrap: break-word !important;\">&nbsp;\u6dfb\u52a0\u5173\u6ce8<\/span><\/span><\/p>\n<p><br  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;line-height: 32px;font-size: 20px;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-family: SimSun;box-sizing: border-box !important;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;line-height: 32px;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;line-height: 32px;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;line-height: 32px;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;line-height: 1.75em;font-family: \u5fae\u8f6f\u96c5\u9ed1, sans-serif;font-size: 15px;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;color: rgb(0, 112, 192);font-family: \u6977\u4f53;box-sizing: border-box !important;word-wrap: break-word !important;\">\u258e\u836f\u660e<\/span><\/strong><strong style=\"max-width: 100%;line-height: 1.75em;font-family: \u5fae\u8f6f\u96c5\u9ed1, sans-serif;font-size: 15px;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;color: rgb(0, 112, 192);font-family: \u6977\u4f53;box-sizing: border-box !important;word-wrap: break-word !important;\">\u5eb7\u5fb7\/<strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-family: SimSun;box-sizing: border-box !important;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;line-height: 1.75em;font-family: \u5fae\u8f6f\u96c5\u9ed1, sans-serif;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-family: \u6977\u4f53;box-sizing: border-box !important;word-wrap: break-word !important;\">\u7f16\u8bd1\uff08\u6765\u6e90\uff1aCRI\uff09<\/span><\/strong><\/strong><\/span><\/strong><\/span><\/strong><\/strong><\/span><\/strong><\/strong><\/span><\/strong><\/strong><\/strong><\/span><\/strong><\/strong><\/span><\/strong><\/strong><\/p>\n<p style=\"padding: 20px 8px 15px;max-width: 100%;min-height: 1em;\"><strong style=\"max-width: 100%;font-size: 1em;line-height: 1.5em;text-decoration: inherit;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;color: rgb(0, 112, 192);font-size: 12px;line-height: 1.5em;text-decoration: inherit;box-sizing: border-box !important;word-wrap: break-word !important;\">\u7f16\u8005\u6309\uff1a<\/span><\/strong><span style=\"max-width: 100%;color: rgb(0, 112, 192);font-size: 12px;text-decoration: inherit;box-sizing: border-box !important;word-wrap: break-word !important;\">\u4f4d\u4e8e\u7ebd\u7ea6\u7684\u764c\u75c7\u7814\u7a76\u6240\uff08Cancer Research Institute\uff0cCRI\uff09\u6210\u7acb\u4e8e1953\u5e74\uff0c\u662f\u5168\u7403\u764c\u75c7\u514d\u75ab\u5b66\u7684\u9886\u5148\u673a\u6784\u3002\u4eca\u5e746\u6708\u4efd\uff0c\u5728\u6210\u7acb65\u5468\u5e74\u4e4b\u9645\uff0cCRI\u516c\u5e03\u4e8630\u9879\u5176\u8d44\u52a9\u7684\u91cd\u8981\u80bf\u7624\u514d\u75ab\u7597\u6cd5\u79d1\u5b66\u7a81\u7834\uff0c\u5b83\u4eec\u5305\u62ec\uff1a1)\u764c\u75c7\u514d\u75ab\u7597\u6cd5\u7684\u57fa\u7840\uff1b2)\u7406\u89e3\u514d\u75ab\u68c0\u67e5\u70b9\u548c\u901a\u8def\uff1b3)\u6297\u764c\u7684\u514d\u75ab\u7ec6\u80de\uff1b4)<span style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\">\u5bf9\u6297\u764c\u75c7\u7684<\/span>\u7ec6\u83cc\u548c\u75ab\u82d7\u3002\u836f\u660e\u5eb7\u5fb7\u7f16\u8bd1\u6574\u7406\u4e86\u8fd930\u4e2a\u7a81\u7834\u6027\u6210\u679c\uff0c\u5206\u4e3a\u4e0a\u4e0b\u4e24\u7bc7\u4e0e\u5927\u5bb6\u4e00\u540c\u5206\u4eab\u3002\u4e0a\u7bc7\u6b22\u8fce\u8bbf\u95ee\uff1a<\/span><a href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MzAwMDA5NTIxNQ==&amp;mid=2649974755&amp;idx=1&amp;sn=89e467a0d4cc6984411f33b0bd8d018e&amp;chksm=82e9e163b59e687514ee8c7d82719e3d7f0819f71325ac0549199326e272b27168bcf52216b6&amp;scene=21#wechat_redirect\" target=\"_blank\" style=\"color: rgb(87, 107, 149);-webkit-tap-highlight-color: rgba(0, 0, 0, 0);max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 12px;color: rgb(0, 112, 192);text-decoration: underline;box-sizing: border-box !important;word-wrap: break-word !important;\">1953-2018\uff0c\u80bf\u7624\u514d\u75ab\u7597\u6cd5\u7684\u7fa4\u661f\u95ea\u8000\u65f6\uff08\u4e0a\u7bc7\uff09<\/span><\/strong><\/a><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/p>\n<section style=\"max-width: 100%;box-sizing: border-box;color: rgb(51, 51, 51);\">\n<section class=\"\"  style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<section class=\"\" style=\"margin-top: 10px;max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<section class=\"\" style=\"padding-left: 5px;max-width: 100%;box-sizing: border-box;display: inline-block;width: 638.4px;border-width: 0px 0px 0px 10px;border-style: solid;border-left-color: rgb(0, 112, 192);border-right-color: rgb(0, 112, 192);word-wrap: break-word !important;\">\n<section class=\"\"  style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;color: rgb(0, 112, 192);word-wrap: break-word !important;\">\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 15px;box-sizing: border-box !important;word-wrap: break-word !important;\">PART3\uff1a\u6297\u764c\u7684\u514d\u75ab\u7ec6\u80de<\/span><\/strong><\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"\"  style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<section class=\"\" style=\"margin-bottom: 8px;max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;background-color: rgb(0, 112, 192);height: 1px;word-wrap: break-word !important;\"><\/section>\n<\/section>\n<\/section>\n<\/section>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><span style=\"max-width: 100%;color: rgb(0, 112, 192);box-sizing: border-box !important;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 15px;box-sizing: border-box !important;word-wrap: break-word !important;\">17. 2002\u5e74\uff1aCassian Yee\u535a\u58eb<\/span><\/strong><\/span><br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><img class=\"\"      style=\"box-sizing: border-box !important;word-wrap: break-word !important;width: auto !important;visibility: visible !important;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/07\/beepress2-1532674347.jpg\" alt=\"1953-2018\uff0c\u80bf\u7624\u514d\u75ab\u7597\u6cd5\u7684\u7fa4\u661f\u95ea\u8000\u65f6\uff08\u4e0b\u7bc7\uff09\" title=\"1953-2018\uff0c\u80bf\u7624\u514d\u75ab\u7597\u6cd5\u7684\u7fa4\u661f\u95ea\u8000\u65f6\uff08\u4e0b\u7bc7\uff09\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><span style=\"max-width: 100%;font-size: 15px;box-sizing: border-box !important;word-wrap: break-word !important;\">\u5728\u5bf9\u6297\u80bf\u7624\u65b9\u9762\uff0c\u514d\u75ab\u7cfb\u7edf\u7684T\u7ec6\u80de\u975e\u5e38\u5f3a\u5927\u3002\u867d\u7136\u5b83\u4eec\u5929\u7136\u80fd\u591f\u8bc6\u522b\u548c\u6d88\u9664\u764c\u7ec6\u80de\uff0c\u4f46\u6709\u65f6\u4e5f\u9700\u8981\u4e00\u4e9b\u5e2e\u52a9\u3002\u5728Fred Hutchinson\u764c\u75c7\u7814\u7a76\u4e2d\u5fc3\u7684\u4e00\u9879\u5f00\u521b\u6027\u5de5\u4f5c\u4e2d\uff0c<strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\">Cassian Yee\u535a\u58eb\u9996\u6b21\u8868\u660e\u9ed1\u8272\u7d20\u7624\u60a3\u8005\u7684\u514d\u75ab\u7ec6\u80de\u53ef\u4ee5\u88ab\u53d6\u51fa\uff0c\u5728\u5b9e\u9a8c\u5ba4\u4e2d\u589e\u5f3a\uff0c\u7136\u540e\u7528\u6765\u5e2e\u52a9\u60a3\u8005\u6297\u764c\u3002<\/strong>\u4ece\u8fd9\u4e9b\u60a3\u8005\u7684\u8840\u6db2\u4e2d\u83b7\u5f97\u514d\u75ab\u7ec6\u80de\u540e\uff0c\u5c06\u7ec6\u80de\u66b4\u9732\u4e8e\u4e24\u79cd\u9ed1\u8272\u7d20\u7624\u7ec6\u80de\u8868\u8fbe\u7684\u6297\u539f\uff08MART1\/MelanA\u548cgp100\uff09\u4e2d\uff0c\u7136\u540e\u6269\u589e\u5b83\u4eec\u7684\u6570\u76ee\u3002\u91cd\u65b0\u8f93\u6ce8\u5230\u60a3\u8005\u4f53\u5185\u540e\uff0c\u8fd9\u4e9b\u7ec6\u80de\u4f1a\u5bfb\u627e\u5e76\u653b\u51fb\u80bf\u7624\uff0c\u7ed3\u679c\u663e\u793a10\u540d\u60a3\u8005\u4e2d\u67098\u540d\u60a3\u8005\u6709\u7597\u6548\u53cd\u5e94\u6216\u81f3\u5c11\u75c5\u60c5\u7a33\u5b9a\u3002\u8fd9\u4e2a\u6700\u521d\u7684\u6982\u5ff5\u9a8c\u8bc1\u968f\u540e\u63a8\u52a8\u4e86\u8bb8\u591a\u8fc7\u7ee7\u6027T\u7ec6\u80de\u514d\u75ab\u6cbb\u7597\u65b9\u6cd5\uff0c\u8fd9\u4e9b\u65b9\u6cd5\u5305\u62ec\u83b7\u5f97\u60a3\u8005\u7684T\u7ec6\u80de\u5e76\u5c06\u5176\u6539\u9020\u4e3a\u4f18\u79c0\u7684\u6297\u764c\u6218\u58eb\uff0c\u7136\u540e\u518d\u5c06\u5176\u9001\u56de\u60a3\u8005\u4f53\u5185\u3002\u57fa\u4e8e\u8be5\u53d1\u73b0\u53d6\u5f97\u6700\u91cd\u8981\u7684\u7a81\u7834\u4e4b\u4e00\u662fCAR-T\u7ec6\u80de\u7597\u6cd5\uff0c\u628a\u60a3\u8005\u6765\u6e90\u7684T\u7ec6\u80de\u914d\u4e0a\u4e13\u95e8\u7684\u53d7\u4f53\uff0c\u4f7f\u5176\u80fd\u591f\u66f4\u6709\u6548\u5730\u9776\u5411\u548c\u6d88\u9664\u764c\u7ec6\u80de\u3002\u76ee\u524d\uff0c\u5df2\u7ecf\u6709\u4e24\u79cdCAR-T\u7ec6\u80de\u514d\u75ab\u7597\u6cd5\u88abFDA\u6279\u51c6\u7528\u4e8e\u6cbb\u7597\u767d\u8840\u75c5\u548c\u6dcb\u5df4\u7624\u3002<\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><span style=\"max-width: 100%;color: rgb(0, 112, 192);box-sizing: border-box !important;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 15px;box-sizing: border-box !important;word-wrap: break-word !important;\">18. 2003\u5e74: E. John Wherry\u535a\u58eb, David Masopust\u535a\u58eb, Rafi Ahmed\u535a\u58eb<\/span><\/strong><\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><span style=\"max-width: 100%;color: rgb(0, 112, 192);box-sizing: border-box !important;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 15px;box-sizing: border-box !important;word-wrap: break-word !important;\"><\/span><\/strong><\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><img class=\"\"      style=\"box-sizing: border-box !important;word-wrap: break-word !important;width: auto !important;visibility: visible !important;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/07\/beepress6-1532674347.jpg\" alt=\"1953-2018\uff0c\u80bf\u7624\u514d\u75ab\u7597\u6cd5\u7684\u7fa4\u661f\u95ea\u8000\u65f6\uff08\u4e0b\u7bc7\uff09\" title=\"1953-2018\uff0c\u80bf\u7624\u514d\u75ab\u7597\u6cd5\u7684\u7fa4\u661f\u95ea\u8000\u65f6\uff08\u4e0b\u7bc7\uff09\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><span style=\"max-width: 100%;font-size: 15px;box-sizing: border-box !important;word-wrap: break-word !important;\">\u4e0d\u540c\u201c\u6740\u624b\u201d\u7ec6\u80de\u5728\u80fd\u529b\u6216\u6301\u4e45\u6027\u65b9\u9762\u90fd\u4e0d\u540c\uff0c\u800c\u57c3\u9ed8\u91cc\u5927\u5b66\u7684E. John Wherry\u535a\u58eb\uff0cDavid Masopust\u535a\u58eb\u548cRafi Ahmed\u535a\u58eb\u8bc1\u5b9e\uff0c<strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\">\u4e2d\u67a2\u8bb0\u5fc6T\u7ec6\u80de\u5728\u5bf9\u6297\u75be\u75c5\u65b9\u9762\u7279\u522b\u6709\u6548\u3002<\/strong>\u540c\u5e74\uff0cWherry\u535a\u58eb\u548cAhmed\u535a\u58eb\u4e5f\u8868\u660e\uff0c\u53ef\u4ee5\u901a\u8fc7\u68c0\u6d4b\u767d\u7ec6\u80de\u4ecb\u7d20-7\u53d7\u4f53\u7684\u8868\u8fbe\u6765\u9274\u5b9a\u4e2d\u67a2\u8bb0\u5fc6T\u7ec6\u80de\u30022003\u5e74\uff0c\u8fd9\u4e2a\u56e2\u961f\u6700\u65e9\u53d1\u73b0\u4e86\u8fd9\u4e9b\u7ec6\u80de\u5728\u5bf9\u4ed8\u75c5\u6bd2\u611f\u67d3\u7684\u91cd\u8981\u6027\uff0c\u4f46\u968f\u540e\uff0c\u7814\u7a76\u8005\u8bc1\u660e\u4e86\u8bb0\u5fc6T\u7ec6\u80de\u4e5f\u5728\u764c\u75c7\u4e2d\u53d1\u6325\u91cd\u8981\u4f5c\u7528\uff0c\u5e76\u4e14\u5b83\u4eec\u6709\u52a9\u4e8e\u6539\u5584\u514d\u75ab\u7597\u6cd5\u7684\u597d\u5904\u3002\u6700\u8fd1\uff0c\u57fa\u4e8e\u7ec6\u80de\u7684\u514d\u75ab\u6cbb\u7597\u65b9\u6cd5\uff0c\u5982CAR-T\u7ec6\u80de\u7597\u6cd5\uff0c\u4e0e\u8fd9\u4e00\u91cd\u8981\u7684\u6740\u4f24\u6027T\u7ec6\u80de\u4e9a\u7fa4\u7684\u7ec4\u5408\u7597\u6cd5\u76ee\u524d\u6b63\u5728\u4e34\u5e8a\u8bd5\u9a8c\u4e2d\u8fdb\u884c\u8bc4\u4f30\u3002<\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><span style=\"max-width: 100%;color: rgb(0, 112, 192);box-sizing: border-box !important;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 15px;box-sizing: border-box !important;word-wrap: break-word !important;\">19\uff0e2014\u5e74\uff1aMichel Sadelain\u535a\u58eb<\/span><\/strong><\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><span style=\"max-width: 100%;color: rgb(0, 112, 192);box-sizing: border-box !important;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 15px;box-sizing: border-box !important;word-wrap: break-word !important;\"><\/span><\/strong><\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><img class=\"\"      style=\"box-sizing: border-box !important;word-wrap: break-word !important;width: auto !important;visibility: visible !important;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/07\/beepress2-1532674347-1.jpg\" alt=\"1953-2018\uff0c\u80bf\u7624\u514d\u75ab\u7597\u6cd5\u7684\u7fa4\u661f\u95ea\u8000\u65f6\uff08\u4e0b\u7bc7\uff09\" title=\"1953-2018\uff0c\u80bf\u7624\u514d\u75ab\u7597\u6cd5\u7684\u7fa4\u661f\u95ea\u8000\u65f6\uff08\u4e0b\u7bc7\uff09\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><span style=\"max-width: 100%;font-size: 15px;box-sizing: border-box !important;word-wrap: break-word !important;\">CAR-T\u7ec6\u80de\u2014\u2014\u4e5f\u88ab\u79f0\u4e3a\u201c\u6d3b\u4f53\u836f\u7269\u201d\u7684\u8f6c\u57fa\u56e0\u514d\u75ab\u7ec6\u80de\u2014\u2014\u5df2\u7ecf\u5f7b\u5e95\u6539\u53d8\u4e86\u767d\u8840\u75c5\u548c\u6dcb\u5df4\u7624\u7b49\u8840\u6db2\u764c\u75c7\u7684\u6cbb\u7597\u65b9\u6cd5\uff0c\u4f46\u5b83\u4eec\u8fd8\u4e0d\u80fd\u6210\u529f\u6cbb\u7597\u4e73\u817a\u764c\u3001\u80ba\u764c\u6216\u80f0\u817a\u764c\u7b49\u5b9e\u4f53\u80bf\u7624\u3002\u539f\u56e0\u4e4b\u4e00\u662f\uff0c\u767d\u8840\u75c5\u7684\u764c\u7ec6\u80de\u5b58\u5728\u4e8e\u8840\u6db2\u5faa\u73af\u4e2d\uff0c\u6dcb\u5df4\u7624\u7684\u764c\u7ec6\u80de\u5b58\u5728\u4e8e\u6dcb\u5df4\u7ed3\uff08\u4e5f\u662f\u514d\u75ab\u7cfb\u7edf\u7684\u4e00\u90e8\u5206\uff09\uff0c\u8fd9\u90fd\u4f7f\u5f97CAR-T\u7ec6\u80de\u66f4\u5bb9\u6613\u63a5\u89e6\u5e76\u6d88\u9664\u764c\u7ec6\u80de\u3002\u53e6\u4e00\u65b9\u9762\uff0c\u5728\u5b9e\u4f53\u7624\u4e2d\uff0cCAR-T\u7ec6\u80de\u5fc5\u987b\u79bb\u5f00\u8840\u6db2\u5faa\u73af\u5e76\u7a7f\u900f\u5668\u5b98\u7684\u81f4\u5bc6\u7ec4\u7ec7\u548c\u5176\u4ed6\u969c\u788d\u624d\u80fd\u5230\u8fbe\u764c\u7ec6\u80de\u3002Memorial Sloan Kettering\u764c\u75c7\u4e2d\u5fc3\u7684Michel Sadelain\u535a\u58eb\u56e2\u961f\u7684\u7814\u7a76\u53d1\u73b0\u6709\u671b\u89e3\u51b3\u8fd9\u4e00\u6311\u6218\u3002<strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\">\u4ed6\u4eec\u5728\u5c0f\u9f20\u4f53\u5185\u53d1\u73b0\u901a\u8fc7CAR-T\u7ec6\u80de\u5c40\u90e8\u7ed9\u836f\u2014\u2014\u8fdb\u5165\u80ba\u90e8\u7684\u80f8\u819c\u8154\uff0c\u800c\u4e0d\u662f\u901a\u8fc7\u9759\u8109\u6ce8\u5c04\u8fdb\u5165\u8840\u6db2\u2014\u2014\u4f1a\u589e\u52a0CAR-T\u7ec6\u80de\u6d3b\u5316\uff0c\u589e\u5f3a\u5176\u6297\u80bf\u7624\u6d3b\u6027\u548c\u5bf9\u95f4\u76ae\u7624\uff08\u4e00\u79cd\u80ba\u90e8\u764c\u75c7\uff09\u7684\u5e94\u7b54\u6301\u4e45\u6027\u3002<\/strong>\u968f\u540e\uff0c\u5728\u5df2\u7ecf\u8111\u8f6c\u79fb\u7684\u764c\u75c7\u60a3\u8005\u4e2d\uff0c\u4e5f\u8bc1\u5b9e\u4e86\u5c40\u90e8\u7ed9\u836f\u53ef\u4ee5\u6539\u5584CAR -T\u7ec6\u80de\u7597\u6cd5\u7684\u6709\u6548\u6027\uff0c\u5e76\u4e14\u4e5f\u53ef\u80fd\u5e94\u7528\u4e8e\u8bb8\u591a\u5176\u4ed6\u764c\u75c7\u4e2d\u3002<\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><span style=\"max-width: 100%;color: rgb(0, 112, 192);box-sizing: border-box !important;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 15px;box-sizing: border-box !important;word-wrap: break-word !important;\">20. 2003\u5e74: Jason Fontenot\u535a\u58eb\uff0cAlexander Rudensky\u535a\u58eb<\/span><\/strong><\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><span style=\"max-width: 100%;color: rgb(0, 112, 192);box-sizing: border-box !important;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 15px;box-sizing: border-box !important;word-wrap: break-word !important;\"><\/span><\/strong><\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><img class=\"\"      style=\"box-sizing: border-box !important;word-wrap: break-word !important;width: auto !important;visibility: visible !important;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/07\/beepress3-1532674348.jpg\" alt=\"1953-2018\uff0c\u80bf\u7624\u514d\u75ab\u7597\u6cd5\u7684\u7fa4\u661f\u95ea\u8000\u65f6\uff08\u4e0b\u7bc7\uff09\" title=\"1953-2018\uff0c\u80bf\u7624\u514d\u75ab\u7597\u6cd5\u7684\u7fa4\u661f\u95ea\u8000\u65f6\uff08\u4e0b\u7bc7\uff09\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><span style=\"max-width: 100%;font-size: 15px;box-sizing: border-box !important;word-wrap: break-word !important;\">\u9664\u4e86\u201c\u6740\u624b\u201dT\u7ec6\u80de\u5916\uff0c\u8fd8\u6709\u5176\u4ed6\u51e0\u79cd\u7c7b\u578b\u7684\u514d\u75ab\u7ec6\u80de\u4f1a\u5f71\u54cd\u6297\u80bf\u7624\u7684\u514d\u75ab\u53cd\u5e94\u3002\u4e00\u79cd\u662f\u8c03\u8282\u6027T\u7ec6\u80de\uff08Tregs\uff09\u3002\u5728\u534e\u76db\u987f\u5927\u5b66\u7684\u4e00\u9879\u91cd\u5927\u53d1\u73b0\u4e2d\uff0cJason Fontenot\u535a\u58eb\u548cAlexander Rudensky\u535a\u58eb\u7684\u7814\u7a76\u8868\u660e\uff0c<strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\">FOXP3\u662f\u63a7\u5236Tregs\u5f62\u6210\u548c\u4fdd\u6301\u6d3b\u6027\u7684\u4e3b\u8981\u5206\u5b50\u5f00\u5173\uff0c\u907f\u514d\u4e86\u53ef\u80fd\u81f4\u547d\u7684\u81ea\u8eab\u514d\u75ab\u53cd\u5e94\u3002<\/strong>\u5c3d\u7ba1Tregs\u5728\u9884\u9632\u81ea\u8eab\u514d\u75ab\u65b9\u9762\u53d1\u6325\u4e86\u6709\u6548\u4f5c\u7528\uff0c\u4f46\u5728\u764c\u75c7\u4e2d\uff0c\u5b83\u4eec\u7684\u4fdd\u62a4\u4f5c\u7528\u53ef\u80fd\u9002\u5f97\u5176\u53cd\u2014\u2014\u4fdd\u62a4\u4e86\u80bf\u7624\u514d\u53d7\u514d\u75ab\u53cd\u5e94\u653b\u51fb\u3002\u4e8b\u5b9e\u4e0a\uff0c\u7b2c\u4e00\u4e2a\u68c0\u67e5\u70b9\u514d\u75ab\u7597\u6cd5\uff082011\u5e74\u88ab\u6279\u51c6\u7528\u4e8e\u665a\u671f\u9ed1\u8272\u7d20\u7624\u7684CTLA-4\u6297\u4f53ipilimumab\uff09\u7684\u6709\u6548\u6027\u5df2\u88ab\u8bc1\u660e\u4e0e\u80bf\u7624\u5fae\u73af\u5883\u4e2dTregs\u7ec6\u80de\u7684\u6d88\u9664\u6709\u5173\u3002<\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><span style=\"max-width: 100%;color: rgb(0, 112, 192);box-sizing: border-box !important;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 15px;box-sizing: border-box !important;word-wrap: break-word !important;\">21\uff0e2018\u5e74\uff1aSusan Kaech\u535a\u58eb<\/span><\/strong><\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><span style=\"max-width: 100%;color: rgb(0, 112, 192);box-sizing: border-box !important;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 15px;box-sizing: border-box !important;word-wrap: break-word !important;\"><\/span><\/strong><\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><img class=\"\"      style=\"box-sizing: border-box !important;word-wrap: break-word !important;width: auto !important;visibility: visible !important;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/07\/beepress9-1532674348.jpg\" alt=\"1953-2018\uff0c\u80bf\u7624\u514d\u75ab\u7597\u6cd5\u7684\u7fa4\u661f\u95ea\u8000\u65f6\uff08\u4e0b\u7bc7\uff09\" title=\"1953-2018\uff0c\u80bf\u7624\u514d\u75ab\u7597\u6cd5\u7684\u7fa4\u661f\u95ea\u8000\u65f6\uff08\u4e0b\u7bc7\uff09\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><span style=\"max-width: 100%;font-size: 15px;box-sizing: border-box !important;word-wrap: break-word !important;\">\u5df2\u7ecf\u88abT\u7ec6\u80de\u8bc6\u522b\u548c\u6e17\u900f\u7684\u201c\u70ed\u201d\u80bf\u7624\u66f4\u6709\u53ef\u80fd\u5bf9\u68c0\u67e5\u70b9\u514d\u75ab\u7597\u6cd5\u6709\u53cd\u5e94\uff0c\u800c\u201c\u51b7\u201d\u80bf\u7624\u901a\u5e38\u5bf9\u514d\u75ab\u7597\u6cd5\u6709\u6297\u6027\u3002\u56e0\u6b64\uff0c\u5927\u591a\u6570\u80bf\u7624\u90fd\u662f\u201c\u51b7\u201d\u80bf\u7624\uff0c\u6025\u9700\u80fd\u591f\u4f7f\u514d\u75ab\u7cfb\u7edf\u66f4\u597d\u5730\u6d88\u706d \u201c\u51b7\u201d\u80bf\u7624\u7684\u65b9\u6cd5\u3002\u4eca\u5e74\uff0c\u8036\u9c81\u5927\u5b66\u7684Susan Kaech\u535a\u58eb<strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\">\u53d1\u73b0\u4e86\u4e00\u79cd\u6f5c\u5728\u7684\u6709\u5e0c\u671b\u7684\u65b9\u6cd5\uff0c\u901a\u8fc7CD40\u548cCSF-1R\u901a\u8def\u9776\u5411\u5de8\u566c\u7ec6\u80de\uff08\u53e6\u4e00\u79cd\u7c7b\u578b\u7684\u514d\u75ab\u7ec6\u80de\uff09<\/strong>\u3002\u8fd9\u79cd\u53cc\u91cd\u7597\u6cd5\u6fc0\u6d3bCD40\u901a\u8def\uff0c\u540c\u65f6\u6291\u5236CSF-1R\u901a\u8def\uff0c\u80fd\u591f\u51cf\u5c11\u514d\u75ab\u6291\u5236\u7684\u5de8\u566c\u7ec6\u80de\u6570\u91cf\uff0c\u5e76\u589e\u52a0\u6297\u80bf\u7624\u708e\u6027\u7684\u5de8\u566c\u7ec6\u80de\u6570\u91cf\uff0c\u4ece\u800c\u80fd\u591f\u5c06\u201c\u51b7\u201d\u80bf\u7624\u8f6c\u5316\u4e3a\u201c\u70ed\u201d\u80bf\u7624\uff0c\u589e\u5f3aT\u7ec6\u80de\u6d3b\u6027\u548c\u80bf\u7624\u6d88\u9664\u3002\u8fd9\u79cd\u65b9\u6cd5\u8fd8\u53ef\u80fd\u4e0e\u68c0\u67e5\u70b9\u514d\u75ab\u7597\u6cd5\u76f8\u7ed3\u5408\uff0c\u8fdb\u4e00\u6b65\u63d0\u9ad8T\u7ec6\u80de\u653b\u51fb\u764c\u7ec6\u80de\u7684\u80fd\u529b\u3002<\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><span style=\"max-width: 100%;color: rgb(0, 112, 192);box-sizing: border-box !important;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 15px;box-sizing: border-box !important;word-wrap: break-word !important;\">22. 2017\u5e74\uff1aRoy Maute\u535a\u58eb\uff0cIrving Weissman\u535a\u58eb<\/span><\/strong><\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><span style=\"max-width: 100%;color: rgb(0, 112, 192);box-sizing: border-box !important;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 15px;box-sizing: border-box !important;word-wrap: break-word !important;\"><\/span><\/strong><\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><img class=\"\"      style=\"box-sizing: border-box !important;word-wrap: break-word !important;width: auto !important;visibility: visible !important;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/07\/beepress1-1532674348.jpg\" alt=\"1953-2018\uff0c\u80bf\u7624\u514d\u75ab\u7597\u6cd5\u7684\u7fa4\u661f\u95ea\u8000\u65f6\uff08\u4e0b\u7bc7\uff09\" title=\"1953-2018\uff0c\u80bf\u7624\u514d\u75ab\u7597\u6cd5\u7684\u7fa4\u661f\u95ea\u8000\u65f6\uff08\u4e0b\u7bc7\uff09\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><span style=\"max-width: 100%;font-size: 15px;box-sizing: border-box !important;word-wrap: break-word !important;\">\u5de8\u566c\u7ec6\u80de\uff08\u4e00\u79cd\u514d\u75ab\u7cfb\u7edf\u7ec6\u80de\uff09\u7684\u4e00\u79cd\u7279\u6b8a\u80fd\u529b\u662f\u901a\u8fc7 \u201c\u541e\u566c\u4f5c\u7528\u201d\u5403\u6389\u635f\u4f24\u6216\u75c5\u6001\u7684\u7ec6\u80de\u3002\u6b63\u5e38\u7ec6\u80de\u8868\u9762\u901a\u8fc7\u8868\u8fbe\u67d0\u4e9b\u6807\u8bb0\u7269\uff0c\u8ba9\u5de8\u566c\u7ec6\u80de\u4e0d\u5403\u5b83\u4eec\uff0c\u4f46\u4e0d\u5e78\u7684\u662f\uff0c\u764c\u7ec6\u80de\u4e5f\u53ef\u4ee5\u5229\u7528\u8fd9\u4e9b\u6807\u8bb0\u7269\u6765\u9a97\u8fc7\u5de8\u566c\u7ec6\u80de\u3002\u4eba\u4eec\u5df2\u7ecf\u77e5\u9053\uff0c\u764c\u7ec6\u80de\u53ef\u4ee5\u4f7f\u7528CD47\u6765\u4fdd\u62a4\u81ea\u5df1\u514d\u53d7\u5de8\u566c\u7ec6\u80de\u7684\u541e\u566c\uff0c\u4f46\u65af\u5766\u798f\u5927\u5b66\u7684Roy Maute\u535a\u58eb\u548cIrving Weissman\u535a\u58eb\u53d1\u73b0\uff0c<strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\">MHC1\u590d\u5408\u7269\u7684\u03b22-\u5fae\u7403\u86cb\u767d\u6210\u5206\u4e5f\u53ef\u88ab\u764c\u7ec6\u80de\u5229\u7528<\/strong>\u3002\u6b64\u5916\uff0c\u4ed6\u4eec\u8868\u660e\uff0c\u7834\u574f\uff08\u764c\u7ec6\u80de\u8868\u9762\u7684\uff09MHC1\u548c\uff08\u5de8\u566c\u7ec6\u80de\u8868\u9762\u7684\uff09LILRB1\u7684\u76f8\u4e92\u4f5c\u7528\u80fd\u591f\u589e\u5f3a\u5de8\u566c\u7ec6\u80de\u4ecb\u5bfc\u7684\u541e\u566c\u4f5c\u7528\uff0c\u66f4\u6709\u6548\u5730\u6d88\u9664\u764c\u7ec6\u80de\u3002\u4e0e\u4e0a\u8ff0Kaech\u535a\u58eb\u7684\u7b56\u7565\u4e00\u6837\uff0c\u8fd9\u79cd\u9776\u5411\u5de8\u566c\u7ec6\u80de\u7684\u65b9\u6cd5\u4e0e\u76ee\u524d\u589e\u5f3aT\u7ec6\u80de\u6297\u764c\u6d3b\u6027\u7684\u514d\u75ab\u6cbb\u7597\u65b9\u6cd5\u76f8\u7ed3\u5408\u5177\u6709\u5f88\u5927\u6f5c\u529b\u3002<\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><span style=\"max-width: 100%;color: rgb(0, 112, 192);box-sizing: border-box !important;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 15px;box-sizing: border-box !important;word-wrap: break-word !important;\">23. 2006\u5e74\uff1aYoshihiro Hayakawa\u535a\u58eb\uff0cMark Smyth\u535a\u58eb<\/span><\/strong><\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><span style=\"max-width: 100%;color: rgb(0, 112, 192);box-sizing: border-box !important;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 15px;box-sizing: border-box !important;word-wrap: break-word !important;\"><\/span><\/strong><\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><img class=\"\"      style=\"box-sizing: border-box !important;word-wrap: break-word !important;width: auto !important;visibility: visible !important;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/07\/beepress7-1532674348.jpg\" alt=\"1953-2018\uff0c\u80bf\u7624\u514d\u75ab\u7597\u6cd5\u7684\u7fa4\u661f\u95ea\u8000\u65f6\uff08\u4e0b\u7bc7\uff09\" title=\"1953-2018\uff0c\u80bf\u7624\u514d\u75ab\u7597\u6cd5\u7684\u7fa4\u661f\u95ea\u8000\u65f6\uff08\u4e0b\u7bc7\uff09\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><span style=\"max-width: 100%;font-size: 15px;box-sizing: border-box !important;word-wrap: break-word !important;\">\u514d\u75ab\u7ec6\u80de\u4e2d\uff0c\u9664\u4e86\u5de8\u566c\u7ec6\u80de\u548c\u201c\u6740\u624b\u201dT\u7ec6\u80de\uff0c\u81ea\u7136\u6740\u4f24\uff08NK\uff09\u7ec6\u80de\u4e5f\u53ef\u4ee5\u5728\u6d88\u9664\u80bf\u7624\u4e2d\u53d1\u6325\u4f5c\u7528\u3002\u6fb3\u5927\u5229\u4e9a\u7684Peter MacCallum\u764c\u75c7\u4e2d\u5fc3\u7684Yoshihiro Hayakawa\u535a\u58eb\u548cMark Smyth\u535a\u58eb\u8868\u660e\uff0c<strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\">NK\u7ec6\u80de\u80fd\u591f\u901a\u8fc7NKG2D\u53d7\u4f53\u901a\u8def\u7684\u76f8\u4e92\u4f5c\u7528\u6765\u4fdd\u62a4\u5c0f\u9f20\u4e0d\u53d1\u751f\u80bf\u7624\u3002<\/strong>\u5728\u611f\u67d3\u6216\u764c\u75c7\u7684\u201c\u538b\u529b\u201d\u4e0b\uff0c\u75c5\u6001\u7ec6\u80de\uff08\u5305\u62ec\u4e00\u4e9b\u764c\u7ec6\u80de\uff09\u8868\u9762\u4f1a\u8868\u8fbe\u4e00\u79cd\u80fd\u88abNKG2D\u901a\u8def\u8bc6\u522b\u548c\u7ed3\u5408\u7684\u86cb\u767d\u8d28\uff0c\u523a\u6fc0NK\u7ec6\u80de\u53d1\u8d77\u653b\u51fb\u3002\u7531\u4e8e\u5bf9NK\u7ec6\u80de\u6297\u80bf\u7624\u80fd\u529b\u7684\u7406\u89e3\u53d6\u5f97\u7684\u8fd9\u9879\u7a81\u7834\uff0c\u7814\u7a76\u4eba\u5458\u5f00\u53d1\u4e86\u51e0\u79cd\u5229\u7528\u8be5\u901a\u8def\u6297\u80bf\u7624\u6f5c\u529b\u7684\u514d\u75ab\u6cbb\u7597\u7b56\u7565\uff0c\u5305\u62ec\u4e00\u4e9b\u901a\u8fc7\u57fa\u56e0\u5de5\u7a0b\u6539\u9020\u4ee5\u8868\u8fbeNKG2D\u53d7\u4f53\u7684CAR-T\u7ec6\u80de\u7597\u6cd5\u3002<\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/p>\n<section style=\"max-width: 100%;box-sizing: border-box;color: rgb(51, 51, 51);\">\n<section class=\"\"  style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<section class=\"\" style=\"margin-top: 10px;max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<section class=\"\" style=\"padding-left: 5px;max-width: 100%;box-sizing: border-box;display: inline-block;width: 638.4px;border-width: 0px 0px 0px 10px;border-style: solid;border-left-color: rgb(0, 112, 192);border-right-color: rgb(0, 112, 192);word-wrap: break-word !important;\">\n<section class=\"\"  style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;color: rgb(0, 112, 192);word-wrap: break-word !important;\">\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 15px;box-sizing: border-box !important;word-wrap: break-word !important;\">PART3\uff1a<span style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\">\u5bf9\u6297\u764c\u75c7\u7684\u7ec6\u83cc\u548c\u75ab\u82d7<\/span><\/span><\/strong><\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"\"  style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<section class=\"\" style=\"margin-bottom: 8px;max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;background-color: rgb(0, 112, 192);height: 1px;word-wrap: break-word !important;\"><\/section>\n<\/section>\n<\/section>\n<\/section>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><span style=\"max-width: 100%;color: rgb(0, 112, 192);box-sizing: border-box !important;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 15px;box-sizing: border-box !important;word-wrap: break-word !important;\">24. 2018\u5e74\uff1aCRI-SU2C\u514d\u75ab\u5b66\u68a6\u4e4b\u961f<\/span><\/strong><\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><span style=\"max-width: 100%;color: rgb(0, 112, 192);box-sizing: border-box !important;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 15px;box-sizing: border-box !important;word-wrap: break-word !important;\"><\/span><\/strong><\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><img class=\"\"      style=\"box-sizing: border-box !important;word-wrap: break-word !important;width: auto !important;visibility: visible !important;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/07\/beepress5-1532674349.jpg\" alt=\"1953-2018\uff0c\u80bf\u7624\u514d\u75ab\u7597\u6cd5\u7684\u7fa4\u661f\u95ea\u8000\u65f6\uff08\u4e0b\u7bc7\uff09\" title=\"1953-2018\uff0c\u80bf\u7624\u514d\u75ab\u7597\u6cd5\u7684\u7fa4\u661f\u95ea\u8000\u65f6\uff08\u4e0b\u7bc7\uff09\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><span style=\"max-width: 100%;font-size: 15px;box-sizing: border-box !important;word-wrap: break-word !important;\">\u4e0e\u5176\u4ed6\u7c7b\u578b\u7684\u764c\u75c7\u76f8\u6bd4\uff0c\u80ba\u764c\u5bfc\u81f4\u7684\u6b7b\u4ea1\u4eba\u6570\u66f4\u591a\u3002\u867d\u7136\u5927\u591a\u6570\u80ba\u90e8\u80bf\u7624\u53ef\u4ee5\u5207\u9664\uff0c\u4f46\u5927\u591a\u6570\u60a3\u8005\u5728\u624b\u672f\u540e\u4ecd\u7136\u4f1a\u590d\u53d1\u3002\u4e3a\u4e86\u89e3\u51b3\u8fd9\u4e2a\u95ee\u9898\uff0cCRI-SU2C\u514d\u75ab\u5b66\u68a6\u4e4b\u961f\u5728\u8fdb\u884c\u4e86\u5173\u4e8e\u672f\u524d\u6297PD-1\u68c0\u67e5\u70b9\u514d\u75ab\u6cbb\u7597\u7684\u7814\u7a76\u3002\u503c\u5f97\u6ce8\u610f\u7684\u662f\uff0c<strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\">\u4ed6\u4eec\u53d1\u73b0\u8fd1\u4e00\u534a\u7684\u60a3\u8005\u5728\u80bf\u7624\u5207\u9664\u524d\u5bf9\u836f\u7269\u6709\u660e\u663e\u53cd\u5e94\u3002<\/strong>\u867d\u7136\u8fd8\u9700\u8981\u66f4\u591a\u7684\u65f6\u95f4\u548c\u7814\u7a76\u6765\u8bc1\u5b9e\u771f\u6b63\u7684\u957f\u671f\u76ca\u5904\uff0c\u4f46\u5230\u76ee\u524d\u4e3a\u6b62\uff0c\u514d\u75ab\u7597\u6cd5\u4f3c\u4e4e\u663e\u793a\u51fa\u9884\u9632\u764c\u75c7\u590d\u53d1\u7684\u4f5c\u7528\u3002\u7814\u7a76\u8d1f\u8d23\u4eba\u3001\u5728\u7ea6\u7ff0\u970d\u666e\u91d1\u65af\u5927\u5b66\u533b\u5b66\u9662\u7684Drew Pardoll\u535a\u58eb\u8bf4\uff1a\u201c\u6211\u4eec\u975e\u5e38\u4e50\u89c2\u5730\u8ba4\u4e3a\u8fd9\u79cd\u65b9\u6cd5\u6700\u7ec8\u5c06\u6539\u53d8\u4e34\u5e8a\u5b9e\u8df5\uff0c\u6709\u671b\u5728\u624b\u672f\u524d\u589e\u5f3a\u5316\u7597\u7684\u4f5c\u7528\u751a\u81f3\u53d6\u4ee3\u5316\u7597\u3002\u201d<\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><span style=\"max-width: 100%;color: rgb(0, 112, 192);box-sizing: border-box !important;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 15px;box-sizing: border-box !important;word-wrap: break-word !important;\">25. 1974\u5e74\uff1aEdgar Lederer\u535a\u58eb<\/span><\/strong><\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><span style=\"max-width: 100%;color: rgb(0, 112, 192);box-sizing: border-box !important;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 15px;box-sizing: border-box !important;word-wrap: break-word !important;\"><\/span><\/strong><\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><img class=\"\"      style=\"box-sizing: border-box !important;word-wrap: break-word !important;width: auto !important;visibility: visible !important;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/07\/beepress2-1532674349.jpg\" alt=\"1953-2018\uff0c\u80bf\u7624\u514d\u75ab\u7597\u6cd5\u7684\u7fa4\u661f\u95ea\u8000\u65f6\uff08\u4e0b\u7bc7\uff09\" title=\"1953-2018\uff0c\u80bf\u7624\u514d\u75ab\u7597\u6cd5\u7684\u7fa4\u661f\u95ea\u8000\u65f6\uff08\u4e0b\u7bc7\uff09\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><span style=\"max-width: 100%;font-size: 15px;box-sizing: border-box !important;word-wrap: break-word !important;\">\u8c08\u5230\u4f53\u5185\u5fae\u751f\u7269\u5982\u7ec6\u83cc\uff0c\u75c5\u6bd2\u548c\u771f\u83cc\uff08\u7edf\u79f0\u4e3a\u5fae\u751f\u7269\u7ec4\uff09\u65f6\uff0c\u6211\u4eec\u60f3\u5230\u7684\u4e3b\u8981\u662f\u5f15\u8d77\u75be\u75c5\u548c\u611f\u67d3\u7684\u8d1f\u9762\u8054\u7cfb\u3002\u7136\u800c\uff0c\u5fae\u751f\u7269\u80fd\u591f\u523a\u6fc0\u514d\u75ab\u7cfb\u7edf\uff0c\u7279\u522b\u662f\u7ec6\u83cc\u8fd8\u53ef\u4ee5\u4fc3\u8fdb\u9488\u5bf9\u764c\u75c7\u7684\u514d\u75ab\u53cd\u5e94\u3002\u4e8b\u5b9e\u4e0a\uff0cCRI\u7684\u521b\u59cb\u4eba\u4e4b\u4e00William B. Coley\u535a\u58eb\u572819\u4e16\u7eaa90\u5e74\u4ee3\u9996\u6b21\u91c7\u7528\u7684\u514d\u75ab\u7597\u6cd5\u5c31\u662f\u5173\u4e8e\u7ec6\u83cc\u611f\u67d3\u764c\u75c7\u60a3\u8005\u30021974\u5e74\uff0c\u5df4\u9ece\u5357\u90e8\u5927\u5b66\u7684Edgar Lederer\u535a\u58eb\u53d1\u73b0\uff0c<strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\">\u7ec6\u83cc\u7ec6\u80de\u58c1\u7684\u7279\u5b9a\u6210\u5206\u80bd\u805a\u7cd6\u5982\u4f55\u523a\u6fc0\u514d\u75ab\u529b<\/strong>\uff0c\u751a\u81f3\u8868\u5f81\u4e86\u8fd9\u79cd\u514d\u75ab\u589e\u5f3a\u6d3b\u52a8\u6240\u9700\u7684\u6700\u5c0f\u7ed3\u6784\u9700\u6c42\u3002\u4e8b\u5b9e\u4e0a\uff0c\u7f8e\u56fdFDA\u4e8e1990\u5e74\u6279\u51c6\u7684\u9996\u4e2a\u514d\u75ab\u7597\u6cd5Bacille Calmette-Guerin\uff08BCG\uff09\uff0c\u5c31\u662f\u5229\u7528\u7ec6\u83cc\u7684\u514d\u75ab\u523a\u6fc0\u7279\u6027\u6cbb\u7597\u65e9\u671f\u8180\u80f1\u764c\u60a3\u8005\u3002<\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><span style=\"max-width: 100%;color: rgb(0, 112, 192);box-sizing: border-box !important;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 15px;box-sizing: border-box !important;word-wrap: break-word !important;\">26\uff0e2008\u5e74: Nicolas Manel\u535a\u58eb\uff0cDan Littman\u535a\u58eb<\/span><\/strong><\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><span style=\"max-width: 100%;color: rgb(0, 112, 192);box-sizing: border-box !important;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 15px;box-sizing: border-box !important;word-wrap: break-word !important;\"><\/span><\/strong><\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><img class=\"\"      style=\"box-sizing: border-box !important;word-wrap: break-word !important;width: auto !important;visibility: visible !important;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/07\/beepress4-1532674349.jpg\" alt=\"1953-2018\uff0c\u80bf\u7624\u514d\u75ab\u7597\u6cd5\u7684\u7fa4\u661f\u95ea\u8000\u65f6\uff08\u4e0b\u7bc7\uff09\" title=\"1953-2018\uff0c\u80bf\u7624\u514d\u75ab\u7597\u6cd5\u7684\u7fa4\u661f\u95ea\u8000\u65f6\uff08\u4e0b\u7bc7\uff09\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><span style=\"max-width: 100%;font-size: 15px;box-sizing: border-box !important;word-wrap: break-word !important;\">\u9664\u4e86\u523a\u6fc0\u514d\u75ab\u53cd\u5e94\u5916\uff0c\u7ec6\u83cc\u8fd8\u5728\u514d\u75ab\u7cfb\u7edf\u7684\u53d1\u80b2\u548c\u6d3b\u6027\u65b9\u9762\u53d1\u6325\u91cd\u8981\u4f5c\u7528\u3002\u7ebd\u7ea6\u5927\u5b66\u533b\u5b66\u9662\u7684Nicolas Manel\u535a\u58eb\u548cDan Littman\u535a\u58eb\u53d1\u73b0\u4e86\u4e00\u79cd\u7279\u6b8a\u514d\u75ab\u7ec6\u80deTh17\u4ecb\u5bfc\u7684\u65b9\u5f0f\u3002\u4ed6\u4eec\u53d1\u73b0<strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\">\u540d\u4e3acytophaga-flavobacter-bacteroidetes\u7684\u7ec6\u83cc\u7684\u5b58\u5728\u4e0eIL17- T\u8f85\u52a9\u7ec6\u80de\u7684\u53d1\u80b2\u6709\u5173\uff0c\u751a\u81f3\u53ef\u80fd\u662f\u5fc5\u9700\u6761\u4ef6<\/strong>\u3002\u5f53\u8fd9\u4e9b\u7ec6\u83cc\u4e0d\u5b58\u5728\u65f6\uff0c\u5b83\u4f1a\u4f7fTh17\u7ec6\u80de\u4e0e\u8c03\u8282\u6027T\u7ec6\u80de\u7684\u6bd4\u4f8b\u53d1\u751f\u504f\u5dee\uff0c\u4ece\u800c\u5f71\u54cd\u80a0\u9053\u514d\u75ab\u529b\u3001\u8010\u53d7\u6027\u548c\u5bf9\u708e\u75c7\u6027\u80a0\u75c5\u7684\u6613\u611f\u6027\u3002<\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><span style=\"max-width: 100%;color: rgb(0, 112, 192);box-sizing: border-box !important;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 15px;box-sizing: border-box !important;word-wrap: break-word !important;\">27. 2015\u5e74\uff1aLeticia Corrales\u535a\u58eb\uff0cThomas Gajewski\u535a\u58eb<\/span><\/strong><\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><span style=\"max-width: 100%;color: rgb(0, 112, 192);box-sizing: border-box !important;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 15px;box-sizing: border-box !important;word-wrap: break-word !important;\"><\/span><\/strong><\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><img class=\"\"      style=\"box-sizing: border-box !important;word-wrap: break-word !important;width: auto !important;visibility: visible !important;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/07\/beepress6-1532674350.jpg\" alt=\"1953-2018\uff0c\u80bf\u7624\u514d\u75ab\u7597\u6cd5\u7684\u7fa4\u661f\u95ea\u8000\u65f6\uff08\u4e0b\u7bc7\uff09\" title=\"1953-2018\uff0c\u80bf\u7624\u514d\u75ab\u7597\u6cd5\u7684\u7fa4\u661f\u95ea\u8000\u65f6\uff08\u4e0b\u7bc7\uff09\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><span style=\"max-width: 100%;font-size: 15px;box-sizing: border-box !important;word-wrap: break-word !important;\">\u6700\u8fd1\uff0cLeticia Corrales\u535a\u58eb\u548cThomas Gajewski\u535a\u58eb\u63ed\u793a\u4e86\u7ec6\u83cc\u5728\u514d\u75ab\u7597\u6cd5\u4e2d\u7684\u4f5c\u7528\u3002\u5728\u8fd9\u9879\u7a81\u7834\u6027\u5de5\u4f5c\u4e2d\uff0c\u4ed6\u4eec\u53d1\u73b0\u8eab\u4f53\u67d0\u4e2a\u90e8\u4f4d\u7684\u7ec6\u83cc\u53ef\u4ee5\u5f71\u54cd\u8eab\u4f53\u5bf9\u5176\u4ed6\u90e8\u4f4d\u764c\u75c7\u7684\u53cd\u5e94\uff0c\u6bd4\u5982\u9ed1\u8272\u7d20\u7624\u3002<strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\">\u5373\u4f7f\u4e0d\u6cbb\u7597\uff0c\u6709\u201c\u597d\u201d\u7ec6\u83cc\uff08\u53cc\u6b67\u6746\u83cc\uff09\u7684\u8001\u9f20\u4e5f\u663e\u793a\u51fa\u5bf9\u80bf\u7624\u7684\u6297\u6027\u3002<\/strong>\u6b64\u5916\uff0c\u5f53\u8fd9\u4e9b\u5c0f\u9f20\u7528\u6297PD-1\u68c0\u67e5\u70b9\u514d\u75ab\u7597\u6cd5\u6cbb\u7597\u65f6\uff0c\u201c\u5b83\u4eec\u7684\u80bf\u7624\u751f\u957f\u51e0\u4e4e\u6d88\u5931\u3002\u201d\u867d\u7136\u4e0a\u8ff0\u7814\u7a76\u662f\u5728\u5c0f\u9f20\u4e2d\u8fdb\u884c\u7684\uff0c\u4f46Gajewski\u535a\u58eb\u9886\u5bfc\u7684\u540e\u7eed\u7814\u7a76\u8868\u660e\uff0c\u4eba\u4f53\u4e5f\u5b58\u5728\u8fd9\u79cd\u76f8\u540c\u7684\u5173\u7cfb\u3002\u764c\u75c7\u60a3\u8005\u4e5f\u662f\u5982\u6b64\u3002\u57fa\u4e8e\u8fd9\u4e9b\u53d1\u73b0\uff0c\u7814\u7a76\u4eba\u5458\u6b63\u5728\u5f00\u53d1\u5229\u7528\u5fae\u751f\u7269\u7ec4\u63d0\u9ad8\u60a3\u8005\u764c\u75c7\u514d\u75ab\u7597\u6cd5\u6210\u529f\u7387\u7684\u65b9\u6cd5\uff0c\u5176\u4e2d\u4e00\u4e9b\u8fdb\u5165\u4e86\u4e34\u5e8a\u7814\u7a76\u3002<\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><span style=\"max-width: 100%;color: rgb(0, 112, 192);box-sizing: border-box !important;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 15px;box-sizing: border-box !important;word-wrap: break-word !important;\">28. 1993\u5e74\uff1aPramod Srivastava\u535a\u58eb<\/span><\/strong><\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><span style=\"max-width: 100%;color: rgb(0, 112, 192);box-sizing: border-box !important;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 15px;box-sizing: border-box !important;word-wrap: break-word !important;\"><\/span><\/strong><\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><img class=\"\"      style=\"box-sizing: border-box !important;word-wrap: break-word !important;width: auto !important;visibility: visible !important;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/07\/beepress6-1532674350-1.jpg\" alt=\"1953-2018\uff0c\u80bf\u7624\u514d\u75ab\u7597\u6cd5\u7684\u7fa4\u661f\u95ea\u8000\u65f6\uff08\u4e0b\u7bc7\uff09\" title=\"1953-2018\uff0c\u80bf\u7624\u514d\u75ab\u7597\u6cd5\u7684\u7fa4\u661f\u95ea\u8000\u65f6\uff08\u4e0b\u7bc7\uff09\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><span style=\"max-width: 100%;font-size: 15px;box-sizing: border-box !important;word-wrap: break-word !important;\">\u514d\u75ab\u7cfb\u7edf\u5bf9\u6297\u764c\u75c7\u7684\u80fd\u529b\u6765\u81ea\u4e8e\u5176\u8bc6\u522b\u548c\u9274\u5b9a\u7a81\u53d8\u7684\u80bf\u7624\u86cb\u767d\u7684\u80fd\u529b\uff0c\u5e76\u4e14\u6709\u51e0\u4e2a\u56e0\u7d20\u53ef\u4ee5\u4fc3\u8fdb\u8fd9\u79cd\u6297\u764c\u6548\u679c\u3002Pramod Srivastava\u535a\u58eb\u7814\u7a76\u4e86\u5176\u4e2d\u4e00\u4e2a\u56e0\u7d20\uff0c\u4ed6\u4eec\u53d1\u73b0<strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\">\u70ed\u4f11\u514b\u86cb\u767d70\uff08hsp70\uff09\u4e0e\u80bf\u7624\u7ec6\u80de\u7684\u6df7\u5408\u7269\u80fd\u591f\u5728\u5c0f\u9f20\u4e2d\u9884\u9632\u80bf\u7624\u7684\u53d1\u751f<\/strong>\u3002\u5728\u8fd9\u9879\u5de5\u4f5c\u4e2d\uff0c\u4ed6\u8fd8\u8868\u660ehsp70\u672c\u8eab\u5e76\u4e0d\u76f4\u63a5\u523a\u6fc0\u514d\u75ab\uff0c\u800c\u662f\u901a\u8fc7\u4e0e\u7a81\u53d8\u7684\u80bf\u7624\u80bd\u7ed3\u5408\uff0c\u4f7f\u514d\u75ab\u7cfb\u7edf\u66f4\u5bb9\u6613\u5730\u8bc6\u522b\u80bf\u7624\u7ec6\u80de\u6765\u5b9e\u73b0\u6297\u764c\u76ee\u7684\u3002\u56e0\u6b64\uff0cSrivastava\u535a\u58eb\u5f00\u53d1\u4e86HSP\u75ab\u82d7OncoPhage\uff0c\u5e76\u4e8e2008\u5e74\u5728\u4fc4\u7f57\u65af\u88ab\u6279\u51c6\u7528\u4e8e\u6cbb\u7597\u80be\u764c\u3002<\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><span style=\"max-width: 100%;color: rgb(0, 112, 192);box-sizing: border-box !important;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 15px;box-sizing: border-box !important;word-wrap: break-word !important;\">29. 2012\u5e74\uff1aMatthew Vesely\u535a\u58eb\u548cRobert Schreiber\u535a\u58eb<\/span><\/strong><\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><span style=\"max-width: 100%;color: rgb(0, 112, 192);box-sizing: border-box !important;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 15px;box-sizing: border-box !important;word-wrap: break-word !important;\"><\/span><\/strong><\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><img class=\"\"      style=\"box-sizing: border-box !important;word-wrap: break-word !important;width: auto !important;visibility: visible !important;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/07\/beepress7-1532674350.jpg\" alt=\"1953-2018\uff0c\u80bf\u7624\u514d\u75ab\u7597\u6cd5\u7684\u7fa4\u661f\u95ea\u8000\u65f6\uff08\u4e0b\u7bc7\uff09\" title=\"1953-2018\uff0c\u80bf\u7624\u514d\u75ab\u7597\u6cd5\u7684\u7fa4\u661f\u95ea\u8000\u65f6\uff08\u4e0b\u7bc7\uff09\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><span style=\"max-width: 100%;font-size: 15px;box-sizing: border-box !important;word-wrap: break-word !important;\">\u80bf\u7624\u7ec6\u80de\u4e0e\u6b63\u5e38\u7ec6\u80de\u7684\u533a\u522b\u5728\u4e8e\u5b83\u4eec\u8868\u8fbe\u7684\u86cb\u767d\u8d28\uff0c\u5c24\u5176\u662f\u5b83\u4eec\u79ef\u7d2f\u7684\u57fa\u56e0\u7a81\u53d8\u5bfc\u81f4\u7684\u5f02\u5e38\u86cb\u767d\u8d28\u3002\u7136\u800c\uff0c\u76f4\u5230\u6700\u8fd1\u4e5f\u6ca1\u6709\u8bc1\u5b9e\u8fd9\u4e9b\u7a81\u53d8\u53ef\u4ee5\u901a\u8fc7\u75ab\u82d7\u5feb\u901f\u8bc6\u522b\u548c\u9776\u5411\u3002\u5e78\u8fd0\u7684\u662f\uff0cMatthew Vesely\u535a\u58eb\u548cRobert Schreiber\u535a\u58eb\u9996\u6b21\u8bc1\u660e\uff0c<strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\">\u6709\u53ef\u80fd\u786e\u5b9a\u54ea\u4e9b\u7a81\u53d8\u86cb\u767d\u8d28\u662f\u7531\u764c\u7ec6\u80de\u4ea7\u751f\u7684\uff0c\u5e76\u4e14\u53ef\u4ee5\u5728\u5c0f\u9f20\u4e2d\u7528\u75ab\u82d7\u9776\u5411\u5b83\u4eec<\/strong>\u3002\u73b0\u5728\uff0c\u8fd9\u4e9b\u4e2a\u4f53\u5316\u7684\u514d\u75ab\u7597\u6cd5\uff08\u79f0\u4e3a\u65b0\u6297\u539f\u75ab\u82d7\uff09\u53ef\u4ee5\u6f5c\u5728\u5730\u6559\u80b2\u60a3\u8005\u7684\u514d\u75ab\u7cfb\u7edf\u8bc6\u522b\u80bf\u7624\u7684\u201c\u6837\u5b50\u201d\uff0c\u6709\u4e00\u4e9b\u80bf\u7624\u75ab\u82d7\u6b63\u5728\u8fdb\u884c\u4e34\u5e8a\u8bd5\u9a8c\uff0c\u800c\u4e14\u5df2\u7ecf\u663e\u793a\u51fa\u6709\u5e0c\u671b\u7684\u521d\u6b65\u6709\u6548\u6570\u636e\u3002<\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><span style=\"max-width: 100%;font-size: 15px;box-sizing: border-box !important;word-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><span style=\"max-width: 100%;color: rgb(0, 112, 192);box-sizing: border-box !important;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 15px;box-sizing: border-box !important;word-wrap: break-word !important;\">30. 2017\u5e74: Sacha Gnjatic\u535a\u58eb\uff0cKunle Odunsi\u535a\u58eb<\/span><\/strong><\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><span style=\"max-width: 100%;color: rgb(0, 112, 192);box-sizing: border-box !important;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 15px;box-sizing: border-box !important;word-wrap: break-word !important;\"><\/span><\/strong><\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><img class=\"\"      style=\"box-sizing: border-box !important;word-wrap: break-word !important;width: auto !important;visibility: visible !important;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/07\/beepress2-1532674351.jpg\" alt=\"1953-2018\uff0c\u80bf\u7624\u514d\u75ab\u7597\u6cd5\u7684\u7fa4\u661f\u95ea\u8000\u65f6\uff08\u4e0b\u7bc7\uff09\" title=\"1953-2018\uff0c\u80bf\u7624\u514d\u75ab\u7597\u6cd5\u7684\u7fa4\u661f\u95ea\u8000\u65f6\uff08\u4e0b\u7bc7\uff09\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><span style=\"max-width: 100%;font-size: 15px;box-sizing: border-box !important;word-wrap: break-word !important;\">\u867d\u7136\u80bf\u7624\u8868\u8fbe\u4e86\u8bb8\u591a\u7531\u7a81\u53d8\u5f15\u8d77\u7684\u5f02\u5e38\u86cb\u767d\u8d28\uff0c\u4f46\u6709\u65f6\u5b83\u4eec\u4e5f\u4f1a\u4e0d\u6070\u5f53\u5730\u8868\u8fbe\u6b63\u5e38\u86cb\u767d\u8d28\u3002\u4e00\u79cd\u7531<em style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\">testis<\/em>\u57fa\u56e0\u7f16\u7801\u7684\u86cb\u767d\u8d28\u901a\u5e38\u4ec5\u5728\u53d1\u80b2\u671f\u95f4\u6216\u5728\u6210\u4eba\u777e\u4e38\u7ec6\u80de\u4e2d\u8868\u8fbe\uff1b\u7136\u800c\uff0c\u764c\u7ec6\u80de\u6709\u65f6\u4f1a\u5f02\u5e38\u5730\u8868\u8fbe\u8be5\u86cb\u767d\u3002<strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\">\u8be5\u86cb\u767d\u5bb6\u65cf\u4e2d\u7684NY-ESO-1\u901a\u5e38\u5728\u51e0\u79cd\u764c\u75c7\u7c7b\u578b\u4e2d\u8868\u8fbe\uff0c\u5c24\u5176\u662f\u5375\u5de2\u764c\uff0c\u8868\u8fbe\u8be5\u86cb\u767d\u8d28\u7684\u80bf\u7624\u901a\u5e38\u66f4\u5177\u4fb5\u88ad\u6027\u5e76\u4e14\u4e0e\u8f83\u4f4e\u7684\u751f\u5b58\u7387\u76f8\u5173\u3002<\/strong>\u56e0\u6b64\uff0c\u7814\u7a76\u8005\u5f00\u53d1\u4e86\u9776\u5411NY-ESO-1\u7684\u75ab\u82d7\u5e76\u7528\u4e8e\u6cbb\u7597\u8fd9\u4e9b\u60a3\u8005\u3002\u503c\u5f97\u6ce8\u610f\u7684\u662f\uff0cRoswell Park\u764c\u75c7\u7814\u7a76\u6240\u7684Kunle Odunsi\u535a\u58eb\u548c\u897f\u5948\u5c71\u4f0a\u574e\u533b\u5b66\u9662\u7684Sacha Gnjatic \u535a\u58eb\u7684\u7814\u7a76\u5de5\u4f5c\u53d1\u73b0\uff0c\u80bf\u7624\u8868\u8fbeNY-ESO-1\u7684\u60a3\u8005\u63a5\u53d7NY-ESO-1\u75ab\u82d7\u540e\uff0c\u6bd4\u672a\u63a5\u79cd\u75ab\u82d7\u7684\u60a3\u8005\u5e73\u5747\u591a\u6d3b\u4e24\u5e74\u3002\u8fd9\u4e9b\u6709\u5e0c\u671b\u7684\u7ed3\u679c\u8bc1\u660e\u4e86\u764c\u75c7\u75ab\u82d7\u7684\u5de8\u5927\u6f5c\u529b\uff0c\u968f\u7740\u9009\u62e9\u75ab\u82d7\u6700\u4f73\u9776\u6807\u7684\u65b9\u6cd5\u4e0d\u65ad\u6539\u8fdb\u548c\u4f18\u5316\uff0c\u764c\u75c7\u75ab\u82d7\u7684\u4f18\u52bf\u4f1a\u66f4\u52a0\u660e\u663e\u3002<\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><span style=\"max-width: 100%;font-size: 10px;color: rgb(178, 178, 178);box-sizing: border-box !important;word-wrap: break-word !important;\">\u53c2\u8003\u8d44\u6599\uff1a<\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);\"><span style=\"max-width: 100%;font-size: 10px;color: rgb(178, 178, 178);box-sizing: border-box !important;word-wrap: break-word !important;\">[1] 30 Days of CRI Impact: Laying the Foundation for Cancer Immunotherapy<\/span><\/p>\n<p><br  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;color: rgb(102, 102, 102);font-family: \u5fae\u8f6f\u96c5\u9ed1;font-size: 14px;font-style: italic;letter-spacing: 0.544px;text-indent: 32px;widows: 1;box-sizing: border-box !important;word-wrap: break-word !important;\">\u6587\u7ae0\u4fe1\u606f\u6e90\u4e8e\u516c<\/span><span style=\"max-width: 100%;color: rgb(102, 102, 102);font-family: \u5fae\u8f6f\u96c5\u9ed1;font-size: 14px;font-style: italic;letter-spacing: 0.544px;text-indent: 32px;widows: 1;box-sizing: border-box !important;word-wrap: break-word !important;\">\u4f17<\/span><span style=\"max-width: 100%;color: rgb(102, 102, 102);font-family: \u5fae\u8f6f\u96c5\u9ed1;font-size: 14px;font-style: italic;letter-spacing: 0.544px;text-indent: 32px;widows: 1;box-sizing: border-box !important;word-wrap: break-word !important;\">\u53f7<\/span><span style=\"max-width: 100%;color: rgb(102, 102, 102);font-family: \u5fae\u8f6f\u96c5\u9ed1;font-size: 14px;font-style: italic;letter-spacing: 0.544px;text-indent: 32px;widows: 1;box-sizing: border-box !important;word-wrap: break-word !important;\">\u836f\u660e\u5eb7\u5fb7<\/span><span style=\"max-width: 100%;color: rgb(102, 102, 102);font-family: \u5fae\u8f6f\u96c5\u9ed1;font-size: 14px;font-style: italic;letter-spacing: 0.544px;text-indent: 32px;widows: 1;box-sizing: border-box !important;word-wrap: break-word !important;\">\uff0c<\/span><span style=\"max-width: 100%;color: rgb(102, 102, 102);font-family: \u5fae\u8f6f\u96c5\u9ed1;font-size: 14px;font-style: italic;letter-spacing: 0.544px;text-indent: 32px;widows: 1;box-sizing: border-box !important;word-wrap: break-word !important;\">\u767b\u8f7d<\/span><span style=\"max-width: 100%;color: rgb(102, 102, 102);font-family: \u5fae\u8f6f\u96c5\u9ed1;font-size: 14px;font-style: italic;letter-spacing: 0.544px;text-indent: 32px;widows: 1;box-sizing: border-box !important;word-wrap: break-word !important;\">\u8be5\u6587\u7ae0\u76ee\u7684\u4e3a\u66f4\u5e7f\u6cdb\u7684\u4f20\u9012\u884c\u4e1a\u4fe1\u606f\uff0c\u4e0d\u4ee3\u8868\u8d5e\u540c\u5176\u89c2\u70b9\u6216\u5bf9\u5176\u771f\u5b9e\u6027\u8d1f\u8d23\u3002\u6587\u7ae0\u7248\u6743\u5f52\u539f\u4f5c\u8005\u53ca\u539f\u51fa\u5904\u6240\u6709\uff0c\u6587\u7ae0\u5185\u5bb9\u4ec5\u4f9b\u53c2\u8003\u3002\u672c\u7f51\u62e5\u6709\u5bf9\u6b64\u58f0\u660e\u7684\u6700\u7ec8\u89e3\u91ca\u6743\uff0c\u82e5\u65e0\u610f\u4fb5\u72af\u7248\u6743\uff0c\u8bf7\u8054\u7cfb\u5c0f\u7f16\u5220\u9664\u3002<\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;word-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/p>\n<p><br  \/><\/p>\n<section  label=\"Powered by 135editor.com\" style=\"max-width: 100%;text-align: center;box-sizing: border-box !important;word-wrap: break-word !important;\">\n<section class=\"\"   style=\"max-width: 100%;box-sizing: border-box;border-width: 0px;border-style: none;border-color: initial;word-wrap: break-word !important;\">\n<section  label=\"Powered by 135editor.com\" style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\">\n<section  label=\"Powered by 135editor.com\" style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\">\n<section  label=\"Powered by 135editor.com\" style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\">\n<section class=\"\"   style=\"max-width: 100%;box-sizing: border-box;border-width: 0px;border-style: none;border-color: initial;word-wrap: break-word !important;\">\n<section class=\"\"  style=\"margin-right: auto;margin-left: auto;max-width: 100%;width: 333.594px;box-sizing: border-box !important;word-wrap: break-word !important;\">\n<section  style=\"max-width: 100%;display: inline-block;width: 333.594px;vertical-align: top;box-sizing: border-box !important;word-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\">\n<section  style=\"max-width: 100%;display: inline-block;vertical-align: top;width: 133.438px;box-sizing: border-box !important;word-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\">\n<section style=\"margin-top: 0.5em;margin-bottom: 0.5em;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box;border-top: 1px dotted rgb(223, 223, 223);word-wrap: break-word !important;\"><\/section>\n<\/section>\n<\/section>\n<\/section>\n<section  style=\"max-width: 100%;display: inline-block;vertical-align: top;width: 50.0312px;box-sizing: border-box !important;word-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\">\n<section style=\"margin-top: 5px;margin-bottom: 10px;max-width: 100%;line-height: 0.8;box-sizing: border-box !important;word-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box;width: 0px;display: inline-block;border-top: 0.8em solid rgb(187, 227, 197);word-wrap: break-word !important;border-left: 0.7em solid transparent !important;border-right: 0.7em solid transparent !important;\"><\/section>\n<\/section>\n<\/section>\n<\/section>\n<section  style=\"max-width: 100%;display: inline-block;vertical-align: top;width: 133.438px;box-sizing: border-box !important;word-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\">\n<section style=\"margin-top: 0.5em;margin-bottom: 0.5em;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box;border-top: 1px dotted rgb(223, 223, 223);word-wrap: break-word !important;\"><\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\">\n<section class=\"\" style=\"padding-right: 10px;padding-left: 10px;max-width: 100%;box-sizing: border-box;text-align: justify;font-size: 14px;letter-spacing: 0px;line-height: 2;color: rgb(160, 160, 160);word-wrap: break-word !important;\">\n<p style=\"max-width: 100%;min-height: 1em;text-indent: 0em;text-align: center;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;color: rgb(136, 136, 136);box-sizing: border-box !important;word-wrap: break-word !important;\">\u5b66\u5982\u9006\u6c34\u884c\u821f\uff0c\u4e0d\u8fdb\u5219\u9000\uff1b<\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;text-indent: 0em;text-align: center;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;color: rgb(136, 136, 136);box-sizing: border-box !important;word-wrap: break-word !important;\">\u5fc3\u4f3c\u5e73\u539f\u8d70\u9a6c\uff0c\u6613\u653e\u96be\u6536\u3002<\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\">\n<section  style=\"max-width: 100%;display: inline-block;vertical-align: top;width: 133.438px;box-sizing: border-box !important;word-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\">\n<section style=\"margin-top: 18px;margin-bottom: 8px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box;border-top: 1px dotted rgb(223, 223, 223);word-wrap: break-word !important;\"><\/section>\n<\/section>\n<\/section>\n<\/section>\n<section  style=\"max-width: 100%;display: inline-block;vertical-align: top;width: 50.0312px;box-sizing: border-box !important;word-wrap: break-word !important;\">\n<section style=\"margin-top: 10px;margin-bottom: 10px;max-width: 100%;line-height: 0.8;box-sizing: border-box !important;word-wrap: break-word !important;\">\n<section   style=\"max-width: 100%;box-sizing: border-box;width: 0px;display: inline-block;border-bottom: 0.8em solid rgb(121, 204, 213);word-wrap: break-word !important;border-left: 0.7em solid transparent !important;border-right: 0.7em solid transparent !important;\"><\/section>\n<\/section>\n<\/section>\n<section  style=\"max-width: 100%;display: inline-block;vertical-align: top;width: 133.438px;box-sizing: border-box !important;word-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\">\n<section style=\"margin-top: 18px;margin-bottom: 8px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box;border-top: 1px dotted rgb(223, 223, 223);word-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;word-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;word-wrap: break-word !important;\"><img class=\"__bg_gif\"       style=\"display: inline;box-sizing: border-box !important;word-wrap: break-word !important;visibility: visible !important;width: 558px !important;\" title=\"1953-2018\uff0c\u80bf\u7624\u514d\u75ab\u7597\u6cd5\u7684\u7fa4\u661f\u95ea\u8000\u65f6\uff08\u4e0b\u7bc7\uff09\" width=\"auto\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/07\/beepress7-1532674351.gif\" alt=\"1953-2018\uff0c\u80bf\u7624\u514d\u75ab\u7597\u6cd5\u7684\u7fa4\u661f\u95ea\u8000\u65f6\uff08\u4e0b\u7bc7\uff09\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;word-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  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1em;letter-spacing: 0.544px;font-family: \u5fae\u8f6f\u96c5\u9ed1;font-size: 14px;color: rgb(35, 21, 10);box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;color: rgb(136, 136, 136);box-sizing: border-box !important;word-wrap: break-word !important;\">\u533b\u836f\u5927\u6570\u636e|\u884c\u4e1a\u52a8\u6001|\u653f\u7b56\u89e3\u8bfb<\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;word-wrap: break-word !important;\"><br  \/><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<blockquote class='keep-source'>\n<p>\u59cb\u53d1\u4e8e\u5fae\u4fe1\u516c\u4f17\u53f7\uff1a                         \u884c\u821fDrug                      <\/p>\n<\/blockquote>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>\u70b9\u51fb\u4e0a\u65b9\u7684&nbsp;\u884c\u821fDrug&nbsp;\u25b2&nbsp;\u6dfb\u52a0\u5173\u6ce8 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