{"id":4583,"date":"2018-07-03T01:00:00","date_gmt":"2018-07-27T06:53:39","guid":{"rendered":"http:\/\/www.05921.net\/index.php\/2018\/07\/27\/2018%e4%b8%8a%e5%8d%8a%e5%b9%b4fda%e6%89%b9%e5%87%86%e7%9a%8417%e4%b8%aa%e6%96%b0%e8%8d%af%e6%b1%87%e6%80%bb%e5%8f%8a%e9%80%90%e4%b8%aa%e8%af%84%e8%bf%b0\/"},"modified":"2018-07-27T14:53:40","modified_gmt":"2018-07-27T06:53:40","slug":"2018%e4%b8%8a%e5%8d%8a%e5%b9%b4fda%e6%89%b9%e5%87%86%e7%9a%8417%e4%b8%aa%e6%96%b0%e8%8d%af%e6%b1%87%e6%80%bb%e5%8f%8a%e9%80%90%e4%b8%aa%e8%af%84%e8%bf%b0","status":"publish","type":"post","link":"https:\/\/www.05921.net\/index.php\/4583\/","title":{"rendered":"2018\u4e0a\u534a\u5e74FDA\u6279\u51c6\u768417\u4e2a\u65b0\u836f\u6c47\u603b\u53ca\u9010\u4e2a\u8bc4\u8ff0"},"content":{"rendered":"<div class=\"bpp-post-content\">\n<p style=\"text-align: center;\"><span style=\"color: rgb(51, 51, 51);\">\u70b9\u51fb\u4e0a\u65b9\u7684&nbsp;\u884c\u821fDrug&nbsp;<\/span><span style=\"max-width: 100%;\">\u25b2&nbsp;\u6dfb\u52a0\u5173\u6ce8<\/span><\/p>\n<p><br  \/><\/p>\n<section class=\"\"  style=\"max-width: 100%;box-sizing: border-box;color: rgb(51, 51, 51);\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;line-height: 2;word-wrap: break-word !important;\">\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;text-indent: 2em;word-wrap: break-word !important;text-align: justify;\">2018\u5e74\u4e0a\u534a\u5e74\uff0cFDA\u836f\u54c1\u5ba1\u8bc4\u4e0e\u7814\u7a76\u4e2d\u5fc3\uff08CDER\uff09\u6279\u51c6\u4e8617\u4e2a\u65b0\u836f\uff0c\u8fd9\u4e9b\u65b0\u836f\u5305\u62ec\u65b0\u836f\u7533\u8bf7NDA\u4e2d\u7684\u65b0\u5206\u5b50\u5b9e\u4f53\uff08NME\uff09\u548c\u751f\u7269\u5236\u54c1\u8bb8\u53ef\u7533\u8bf7\uff08BLA\uff09\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"\"  style=\"max-width: 100%;box-sizing: border-box;color: rgb(51, 51, 51);\">\n<section class=\"\" style=\"margin-top: 10px;margin-bottom: 10px;max-width: 100%;box-sizing: border-box;text-align: center;word-wrap: break-word !important;\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;vertical-align: middle;display: inline-block;word-wrap: break-word !important;overflow: hidden !important;\"><img class=\"\"     style=\"box-sizing: border-box;vertical-align: middle;word-wrap: break-word !important;visibility: visible !important;width: auto !important;\" width=\"auto\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/07\/beepress3-1532674420.png\" alt=\"2018\u4e0a\u534a\u5e74FDA\u6279\u51c6\u768417\u4e2a\u65b0\u836f\u6c47\u603b\u53ca\u9010\u4e2a\u8bc4\u8ff0\" title=\"2018\u4e0a\u534a\u5e74FDA\u6279\u51c6\u768417\u4e2a\u65b0\u836f\u6c47\u603b\u53ca\u9010\u4e2a\u8bc4\u8ff0\"  \/><\/section>\n<\/section>\n<\/section>\n<section class=\"\"  style=\"max-width: 100%;box-sizing: border-box;color: rgb(51, 51, 51);\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;line-height: 2;word-wrap: break-word !important;\">\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;text-indent: 2em;word-wrap: break-word !important;\"><span style=\"max-width: 100%;box-sizing: border-box;letter-spacing: 0px;line-height: 2;word-wrap: break-word !important;\">\u4e0a\u56fe\u662f\u8fc7\u53bb10\u5e74\u4e2d\uff0cCDER\u6bcf\u5e74\u6279\u51c6\u7684\u65b0\u836f\u6570\u30022018\u5e74\u4e0a\u534a\u5e74CDER\u6279\u51c6\u7684\u65b0\u836f\u5305\u62ec5\u4e2aBLA\u548c12\u4e2aNME\u3002\u76f8\u6bd4\u4e8e2017\u5e74\u4e0a\u534a\u5e74\u768423\u4e2a\u51cf\u5c11\u4e866\u4e2a\uff0c\u7565\u9ad8\u4e8e2016\u4e0a\u534a\u5e74\u548c2015\u4e0a\u534a\u5e74\u3002<\/span><\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;word-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;text-indent: 0em;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\">\u7f55\u89c1\u75c5\/\u5b64\u513f\u836f<\/strong><\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;text-indent: 0em;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\">(<\/strong><span style=\"max-width: 100%;font-size: 16px;box-sizing: border-box !important;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\">Rare&nbsp;OR &#8220;Orphan&#8221;&nbsp;Diseases<\/strong><\/span><strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\">)<\/strong><\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;text-indent: 2em;word-wrap: break-word !important;\"><span style=\"max-width: 100%;box-sizing: border-box;text-indent: 2em;letter-spacing: 0px;line-height: 2;word-wrap: break-word !important;\">\u5df2\u6279\u51c6\u768417\u4e2a\u65b0\u836f\u4e2d\uff0c8\u4e2a\u65b0\u836f\u83b7\u5f97\u4e86\u5b64\u513f\u836f\u8d44\u683c\uff08O\uff09\uff0c\u5360CDER\u6279\u51c6\u65b0\u836f\u768447%\u3002\u7f55\u89c1\u75c5\u6709\u4e24\u4e2a\u7279\u5f81\uff0c\u5176\u4e00\u4e3a\u60a3\u8005\u4eba\u6570\u5c11\uff0c\u7f8e\u56fd\u4e3a\u5c11\u4e8e20\u4e07\u4eba\u7684\u75be\u75c5\uff0c\u6b27\u76df\u5c5e\u4e8e5\/10000\u7684\u75be\u75c5\uff1b\u5176\u4e8c\u4e3a\u5371\u53ca\u751f\u547d\u548c\u5065\u5eb7\u7684\u4e25\u91cd\u75be\u75c5\u3002<\/span><\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;text-indent: 2em;word-wrap: break-word !important;\"><span style=\"max-width: 100%;box-sizing: border-box;text-indent: 2em;letter-spacing: 0px;line-height: 2;word-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\">\u4f18\u5148\u5ba1\u8bc4\uff08Priority Review\uff09<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"\"  style=\"max-width: 100%;box-sizing: border-box;color: rgb(51, 51, 51);\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;line-height: 2;word-wrap: break-word !important;\">\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;text-indent: 2em;word-wrap: break-word !important;\">\u5982\u679cCDER\u786e\u5b9a\u836f\u54c1\u80fd\u591f\u6709\u6f5c\u529b\u5bf9\u533b\u7597\u4fdd\u5065\u505a\u51fa\u5b9e\u8d28\u6027\u63a8\u52a8\uff0c\u836f\u54c1\u5c06\u83b7\u5f97\u4f18\u5148\u5ba1\u8bc4\u3002\u836f\u54c1\u57286\u4e2a\u6708\u5185\u800c\u4e0d\u662f\u6807\u51c6\u768410\u4e2a\u6708\u5185\u5ba1\u8bc4\u30022018\u5e74\u4e0a\u534a\u5e74\u83b7\u6279\u65b0\u836f\u4e2d\u67098\u4e2a\u88ab\u8ba4\u5b9a\u4e3a\u4f18\u5148\u5ba1\u8bc4\uff08P\uff09\uff0c\u536017\u4e2a\u65b0\u836f\u768447%\u3002<\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;word-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;text-indent: 2em;word-wrap: break-word !important;\">CDER\u5e94\u7528\u591a\u79cd\u76d1\u7ba1\u65b9\u6cd5\u52a0\u5feb\u65b0\u836f\u7814\u53d1\u548c\u5ba1\u6279\u3002\u8fd9\u4e9b\u65b9\u6cd5\u9664\u4e86\u4f18\u5148\u5ba1\u8bc4\u8fd8\u5305\u62ec\uff1a\u5feb\u901f\u901a\u9053\uff08Fast Track\uff09\u3001\u7a81\u7834\u6027\u6cbb\u7597\u8ba4\u5b9a\uff08Breakthrough\uff09\u548c\u52a0\u901f\u6279\u51c6\uff08Accelerated Approval\uff09\u3002<\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;word-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;text-indent: 2em;word-wrap: break-word !important;\">\u6cbb\u7597\u9886\u57df\u65b9\u9762\uff0c2018\u5e74\u4e0a\u534a\u5e74\u8fd8\u662f\u6bd4\u8f83\u4e30\u5bcc\uff0c\u6297\u80bf\u7624\u836f\u660e\u663e\u51cf\u5c11\uff0c\u4ec5\u67092\u4e2a\u3002\u6574\u4f53\u6765\u8bf4\uff0c\u7f8e\u56fdFDA\u8fd8\u662f\u5404\u836f\u4f01\u65b0\u836f\u4e0a\u5e02\u7684\u9996\u9009\uff0c17\u4e2a\u65b0\u836f\u670912\u4e2a\u836f\u7269\u90fd\u662f\u5168\u7403\u9996\u6279\uff0c\u5176\u4f59\u7684\u5927\u591a\u5728\u6b27\u76df\u9996\u6279\u3002<\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;text-indent: 2em;word-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;text-indent: 2em;word-wrap: break-word !important;\">\u4e0b\u8868\u4e3a2018\u5e74\u6279\u51c6\u768417\u4e2a\u65b0\u836f\u6c47\u603b\uff0c\u6765\u6e90\u4e8eFDA\u7f51\u7ad9\uff0cNovel Drug Approvals for2018\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"\"  style=\"max-width: 100%;box-sizing: border-box;color: rgb(51, 51, 51);\">\n<section class=\"\" style=\"margin-top: 10px;margin-bottom: 10px;max-width: 100%;box-sizing: border-box;text-align: center;word-wrap: break-word !important;\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;vertical-align: middle;display: inline-block;word-wrap: break-word !important;overflow: hidden !important;\"><img class=\"\"     style=\"box-sizing: border-box;vertical-align: middle;word-wrap: break-word !important;visibility: visible !important;width: auto !important;\" width=\"auto\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/07\/beepress7-1532674420.jpg\" alt=\"2018\u4e0a\u534a\u5e74FDA\u6279\u51c6\u768417\u4e2a\u65b0\u836f\u6c47\u603b\u53ca\u9010\u4e2a\u8bc4\u8ff0\" title=\"2018\u4e0a\u534a\u5e74FDA\u6279\u51c6\u768417\u4e2a\u65b0\u836f\u6c47\u603b\u53ca\u9010\u4e2a\u8bc4\u8ff0\"  \/><\/section>\n<\/section>\n<\/section>\n<section class=\"\"  style=\"max-width: 100%;box-sizing: border-box;color: rgb(51, 51, 51);\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;word-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\"  \/><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"\"  style=\"max-width: 100%;box-sizing: border-box;color: rgb(51, 51, 51);\">\n<section class=\"\" style=\"margin-top: 10px;margin-bottom: 10px;max-width: 100%;box-sizing: border-box;text-align: center;word-wrap: break-word !important;\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;display: inline-block;vertical-align: top;width: 0.5em;height: 1.8em;border-bottom: 0.9em solid rgb(36, 96, 178);border-top: 0.9em solid rgb(36, 96, 178);word-wrap: break-word !important;border-left: 0.9em solid transparent !important;\"><\/section>\n<section class=\"\" style=\"padding-right: 8px;padding-left: 8px;max-width: 100%;box-sizing: border-box;display: inline-block;vertical-align: top;height: 1.8em;line-height: 1.8em;color: rgb(255, 255, 255);background-color: rgb(36, 96, 178);word-wrap: break-word !important;\">\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\u54c1\u79cd\u8bc4\u8ff0<\/strong><\/p>\n<\/section>\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;display: inline-block;vertical-align: top;width: 0.5em;height: 1.8em;border-bottom: 0.9em solid rgb(36, 96, 178);border-top: 0.9em solid rgb(36, 96, 178);word-wrap: break-word !important;border-right: 0.9em solid transparent !important;\"><\/section>\n<\/section>\n<\/section>\n<section class=\"\"  style=\"max-width: 100%;box-sizing: border-box;color: rgb(51, 51, 51);\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<section class=\"\" style=\"padding: 10px;max-width: 100%;box-sizing: border-box;display: inline-block;width: 677px;border-width: 0px 0px 0px 6px;border-style: solid;border-left-color: rgb(36, 96, 178);border-right-color: rgb(36, 96, 178);word-wrap: break-word !important;\">\n<section class=\"\"  style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">01&nbsp;Lutathera&nbsp;<\/strong><\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\uff08lutetium Lu 177 dotatate\uff09<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"\"  style=\"max-width: 100%;box-sizing: border-box;color: rgb(51, 51, 51);\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;line-height: 2;word-wrap: break-word !important;\">\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;text-indent: 2em;word-wrap: break-word !important;\">1\u670826\u65e5\uff0cFDA\u6279\u51c6\u4e86\u8bfa\u534e\u5b50\u516c\u53f8\u6cd5\u56fdAdvanced Accelerator Applications \u516c\u53f8Lutathera\u7528\u4e8e\u6cbb\u7597\u5f71\u54cd\u80f0\u817a\u6216\u80c3\u80a0\u9053\u7684\u4e00\u7c7b\u764c\u75c7\uff0c\u5373\u80c3\u80a0\u80f0\u817a\u795e\u7ecf\u5185\u5206\u6ccc\u80bf\u7624\uff08GEP-NETs\uff09\u3002<\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;word-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;text-indent: 2em;word-wrap: break-word !important;\">Lutathera\u662f\u4e00\u79cdLu-177\u6807\u8bb0\u7684\u751f\u957f\u6291\u7d20\u7c7b\u4f3c\u7269\uff0c\u5c5e\u4e8e\u65b0\u5174\u7684\u80bd\u53d7\u4f53\u653e\u5c04\u6027\u6838\u7d20\u7597\u6cd5\uff08PRRT\uff09\uff0c\u901a\u8fc7\u4e0e\u4e00\u79cd\u79f0\u4e3a\u751f\u957f\u6fc0\u7d20\u6291\u5236\u7d20\u53d7\u4f53\u7684\u7ec6\u80de\u7ed3\u5408\u800c\u8d77\u4f5c\u7528\uff0c\u8be5\u751f\u957f\u6291\u7d20\u53d7\u4f53\u53ef\u80fd\u5b58\u5728\u4e8e\u67d0\u4e9b\u80bf\u7624\u4e0a\u3002\u5728\u4e0e\u53d7\u4f53\u7ed3\u5408\u4e4b\u540e\uff0c\u836f\u7269\u8fdb\u5165\u7ec6\u80de\uff0c\u91ca\u653e\u8f90\u5c04\u6765\u635f\u4f24\u80bf\u7624\u7ec6\u80de\u3002<\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;word-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;text-indent: 2em;word-wrap: break-word !important;\">\u5728\u7f8e\u56fd\u548c\u6b27\u76df\uff0cLutathera\u5747\u88ab\u6388\u4e88\u5b64\u513f\u836f\u5730\u4f4d\u3002\u6b27\u76df\u5df2\u4e8e2017\u5e7410\u6708\u6279\u51c6\u7528\u4e8e\u6cbb\u7597\u4e0d\u53ef\u5207\u9664\u6216\u8f6c\u79fb\u7684\u751f\u957f\u6291\u7d20\u53d7\u4f53\u9633\u6027\u80c3\u80a0\u80f0\u817a\u795e\u7ecf\u5185\u5206\u6ccc\u80bf\u7624\u6210\u4eba\u60a3\u8005\u3002\u8fd9\u4e5f\u662f\u653e\u5c04\u6027\u836f\u7269\u9996\u6b21\u88abFDA\u6279\u51c6\u7528\u4e8e\u6cbb\u7597GEP-NETs\u3002<\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;text-indent: 2em;word-wrap: break-word !important;\">&nbsp;<\/p>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"\"  style=\"max-width: 100%;box-sizing: border-box;color: rgb(51, 51, 51);\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<section class=\"\" style=\"padding: 10px;max-width: 100%;box-sizing: border-box;display: inline-block;width: 677px;border-width: 0px 0px 0px 6px;border-style: solid;border-left-color: rgb(36, 96, 178);border-right-color: rgb(36, 96, 178);word-wrap: break-word !important;\">\n<section class=\"\"  style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">02&nbsp;Biktarvy<\/strong><\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">&nbsp;\uff08bictegravir,&nbsp;<\/strong><strong style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">embitcitabine,&nbsp;<\/strong><\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">tenofovir alafenamide\uff09<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"\"  style=\"max-width: 100%;box-sizing: border-box;color: rgb(51, 51, 51);\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;line-height: 2;word-wrap: break-word !important;\">\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;text-indent: 2em;word-wrap: break-word !important;\">2\u67087\u65e5\uff0cFDA\u6279\u51c6\u4e86Gilead\u516c\u53f8\u7684Biktarvy\uff0c\u4f5c\u4e3a\u6bcf\u65e5\u4e00\u6b21\u7684\u5355\u7247\u7247\u5242\u7597\u6cd5\uff0c\u7528\u4e8e\u6cbb\u7597HIV-1\u611f\u67d3\u3002<\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;text-indent: 2em;word-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;text-indent: 2em;word-wrap: break-word !important;\">Biktarvy\u662f\u4e00\u6b3e\u5168\u65b0\u7684\u65e0\u52a9\u63a8\uff08unboosted\uff09\u6574\u5408\u9176\u94fe\u8f6c\u79fb\u6291\u5236\u5242\uff08INSTI\uff09\uff0c\u7531bictegravir\uff0850mg\uff09\u3001emtricitabine\uff08200mg\uff09\u3001\u4e0etenofovir alafenamide\uff0825mg\uff09\u4e09\u79cd\u6210\u5206\u7ec4\u6210\u3002<\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;word-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;text-indent: 2em;word-wrap: break-word !important;\">Biktarvy\u7684\u7597\u6548\u4e0e\u5b89\u5168\u6027\u57284\u9879\u6b63\u5728\u8fdb\u884c\u76843\u671f\u4e34\u5e8a\u8bd5\u9a8c\u4e2d\u5f97\u5230\u4e86\u9a8c\u8bc1\u3002\u8bd5\u9a8c1489\u548c1490\u62db\u52df\u7684\u662f\u521d\u6cbb\u7684HIV-1\u611f\u67d3\u6210\u4eba\u60a3\u8005\uff0c\u800c\u8bd5\u9a8c1844\u4e0e1878\u5219\u62db\u52df\u4e86\u75c5\u6bd2\u611f\u67d3\u5728\u75c5\u6bd2\u5b66\u4e0a\u5f97\u5230\u6291\u5236\u7684\u6210\u4eba\u60a3\u8005\u3002<\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;word-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;text-indent: 2em;word-wrap: break-word !important;\">\u5728\u8bd5\u9a8c1489\u4e2d\uff0c629\u540d\u60a3\u8005\u4ee51\uff1a1\u7684\u6bd4\u4f8b\u5206\u4e3a\u4e24\u7ec4,\u5206\u522b\u63a5\u53d7Biktarvy\u4e0eabacavir\/dolutegravir\/lamivudine\uff08600\/50\/300mg\uff09\u7684\u6cbb\u7597\u3002\u572848\u5468\u540e\uff0c\u8fd9\u4e24\u7ec4\u60a3\u8005\u4e2d\uff0c\u5206\u522b\u670992.4%\u548c93.0%\u7684\u60a3\u8005\u8fbe\u5230\u4e86HIV-1 RNA\u5c0f\u4e8e\u6bcf\u6beb\u534750c\u7684\u4e3b\u8981\u7ec8\u70b9\u3002\u800c\u5728\u8bd5\u9a8c1490\u4e2d\uff0c645\u540d\u60a3\u8005\u63a5\u53d7\u7684\u5206\u522b\u662fBiktarvy\u4e0edolutegravir\/FTC\/TAF\u3002\u540c\u6837\uff0c\u4e24\u7ec4\u8fbe\u5230\u4e3b\u8981\u7ec8\u70b9\u7684\u6bd4\u4f8b\u63a5\u8fd1\uff0c\u5206\u522b\u4e3a89.4%\u4e0e92.9%\u3002<\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;word-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;text-indent: 2em;word-wrap: break-word !important;\">\u5728\u8bd5\u9a8c1878\u4e2d\uff0c577\u540d\u5728\u836f\u7269\u4f5c\u7528\u4e0b\uff0cHIV-1 RNA\u5df2\u7ecf\u5c0f\u4e8e\u6bcf\u6beb\u534750c\u7684\u6210\u4eba\u60a3\u8005\u88ab1\uff1a1\u5206\u4e3a\u4e24\u7ec4\uff0c\u4e00\u7ec4\u7ee7\u7eed\u73b0\u6709\u7684\u7597\u6cd5\uff0c\u53e6\u4e00\u7ec4\u5219\u5207\u6362\u5230Biktarvy\u7684\u6cbb\u7597\u3002\u572848\u5468\u540e\uff0c\u4e24\u7ec4\u4e2d\u5747\u67091.7%\u7684\u60a3\u8005\u5176HIV-1 RNA\u56de\u5230\u4e0d\u4f4e\u4e8e\u6bcf\u6beb\u534750c\u7684\u6c34\u5e73\uff1b\u800c\u6839\u636eFDA\u7684\u7b97\u6cd5\uff0c\u5206\u522b\u670992.1%\uff08Biktarvy\u7ec4\uff09\u4e0e88.9%\uff08\u73b0\u6709\u7597\u6cd5\u7ec4\uff09\u7684\u60a3\u8005\u4fdd\u6301\u4e86HIV-1 RNA\u5c0f\u4e8e\u6bcf\u6beb\u534750c\u3002<\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;word-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\"  \/><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"\"  style=\"max-width: 100%;box-sizing: border-box;color: rgb(51, 51, 51);\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<section class=\"\" style=\"padding: 10px;max-width: 100%;box-sizing: border-box;display: inline-block;width: 677px;border-width: 0px 0px 0px 6px;border-style: solid;border-left-color: rgb(36, 96, 178);border-right-color: rgb(36, 96, 178);word-wrap: break-word !important;\">\n<section class=\"\"  style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">03&nbsp;Symdeko&nbsp;<\/strong><\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\uff08tezacaftor; ivacafto\uff09<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"\"  style=\"max-width: 100%;box-sizing: border-box;color: rgb(51, 51, 51);\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;line-height: 2;word-wrap: break-word !important;\">\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;text-indent: 2em;word-wrap: break-word !important;\">2\u670813\u65e5\uff0cFDA\u6279\u51c6\u4e86Vertex\u533b\u836f\u516c\u53f8\u7684Symdeko\u4e0a\u5e02\uff0c\u7528\u4e8e\u6cbb\u759712\u5c81\u53ca\u4ee5\u4e0a\u7684\u56ca\u6027\u7ea4\u7ef4\u5316\uff08cystic fibrosis\uff0cCF\uff09\u60a3\u8005\u3002SYMDEKO\u662fVertex\u83b7\u5f97FDA\u6279\u51c6\u7684\u7b2c3\u79cd\u9488\u5bf9\u56ca\u6027\u7ea4\u7ef4\u5316\u6839\u672c\u75c5\u56e0\u7684\u6cbb\u7597\u836f\u7269\u3002<\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;word-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;text-indent: 2em;word-wrap: break-word !important;\">\u56ca\u6027\u7ea4\u7ef4\u5316\u662f\u4e00\u79cd\u7f55\u89c1\u7684\u4f1a\u7f29\u77ed\u5bff\u547d\u7684\u9057\u4f20\u75be\u75c5\uff0c\u5f71\u54cd\u4e86\u5317\u7f8e\u3001\u6b27\u6d32\u548c\u6fb3\u5927\u5229\u4e9a\u7ea6 75000 \u540d\u60a3\u8005\uff0c\u7531\u57fa\u56e0\u7a81\u53d8\u5bfc\u81f4\u7684 CFTR \u86cb\u767d\u7f3a\u9677\u6216\u7f3a\u5931\u5f15\u8d77\u3002\u513f\u7ae5\u5fc5\u987b\u9057\u4f20\u5230\u4e24\u4e2a\u6709\u7f3a\u9677\u7684 CFTR \u57fa\u56e0\u2014\u2014\u5206\u522b\u6765\u81ea\u7236\u6bcd\uff0c\u624d\u4f1a\u60a3\u56ca\u6027\u7ea4\u7ef4\u5316\u3002CFTR \u57fa\u56e0\u4e2d\u6709\u7ea6 2000 \u4e2a\u5df2\u77e5\u7684\u7a81\u53d8\uff0c\u5176\u4e2d\u4e00\u4e9b\u7a81\u53d8\u4f1a\u901a\u8fc7\u5728\u7ec6\u80de\u8868\u9762\u4ea7\u751f\u4e0d\u5de5\u4f5c\u6216\u8fc7\u5c11\u7684 CFTR \u86cb\u767d\uff0c\u5b83\u4eec\u53ef\u4ee5\u901a\u8fc7\u57fa\u56e0\u68c0\u6d4b\u6216\u57fa\u56e0\u5206\u578b\u68c0\u6d4b\u6765\u786e\u5b9a\u3002CFTR \u86cb\u767d\u7684\u529f\u80fd\u7f3a\u9677\u6216\u7f3a\u5931\u5bfc\u81f4\u8bb8\u591a\u5668\u5b98\u7ec6\u80de\u4e2d\u76d0\u548c\u6c34\u7684\u6d41\u5165\u548c\u6d41\u51fa\u4e0d\u5747\u8861\u3002\u5728\u80ba\u4e2d\uff0c\u8fd9\u4f1a\u9020\u6210\u5f02\u5e38\u7c98\u7a20\u7684\u7c98\u6db2\u79ef\u805a\uff0c\u5f15\u8d77\u6162\u6027\u80ba\u90e8\u611f\u67d3\u548c\u8fdb\u884c\u6027\u80ba\u635f\u4f24\uff0c\u5e76\u6700\u7ec8\u5bfc\u81f4\u6b7b\u4ea1\u3002\u56ca\u6027\u7ea4\u7ef4\u5316\u60a3\u8005\u7684\u4e2d\u4f4d\u5bff\u547d\u5728 20 \u5c81\u5de6\u53f3\u3002<\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;word-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;text-indent: 2em;word-wrap: break-word !important;\">\u636e\u6089\uff0c\u6b27\u6d32\u836f\u54c1\u7ba1\u7406\u5c40\uff08EMA\uff09\u5df2\u7ecf\u786e\u8ba4\u4e86tezacaftor\/ivacaftor\u7ec4\u5408\u836f\u7269\u7684\u8425\u9500\u6388\u6743\u7533\u8bf7\uff08MAA\uff09\u3002\u516c\u53f8\u9884\u8ba1\u57282018\u5e74\u4e0b\u534a\u5e74\u83b7\u5f97\u6b27\u76df\u6279\u51c6\u3002<\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;word-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\"  \/><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"\"  style=\"max-width: 100%;box-sizing: border-box;color: rgb(51, 51, 51);\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<section class=\"\" style=\"padding: 10px;max-width: 100%;box-sizing: border-box;display: inline-block;width: 677px;border-width: 0px 0px 0px 6px;border-style: solid;border-left-color: rgb(36, 96, 178);border-right-color: rgb(36, 96, 178);word-wrap: break-word !important;\">\n<section class=\"\"  style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">04&nbsp;Erleada(apalutamide)<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"\"  style=\"max-width: 100%;box-sizing: border-box;color: rgb(51, 51, 51);\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;line-height: 2;word-wrap: break-word !important;\">\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;text-indent: 2em;word-wrap: break-word !important;\">2\u670814\u65e5\uff0cFDA\u6279\u51c6\u5f3a\u751fErleada (apalutamide) \u4e0a\u5e02\uff0c\u7528\u4e8e\u6cbb\u7597\u975e\u8f6c\u79fb\u6027\uff08\u524d\u5217\u817a\u764c\u7ec6\u80de\u672a\u6269\u6563\uff09\u53bb\u52bf\u62b5\u6297\uff08\u6fc0\u7d20\u6cbb\u7597\u540e\u75be\u75c5\u4ecd\u8fdb\u5c55\uff09\u7684\u524d\u5217\u817a\u764c\u3002<\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;word-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;text-indent: 2em;word-wrap: break-word !important;\">Erleada\u83b7\u5f97\u8fc7FDA\u7684\u4f18\u5148\u5ba1\u8bc4\u8d44\u683c\uff0c\u662fFDA\u6279\u51c6\u7684\u9996\u4e2a\u6cbb\u7597\u975e\u8f6c\u79fb\u6027\u53bb\u52bf\u62b5\u6297\u524d\u5217\u817a\u764c\u7684\u836f\u7269\uff0c\u4e5f\u662f\u9996\u4e2a\u51ed\u501f\u65e0\u8f6c\u79fb\u751f\u5b58\u671f\uff08metastasis-free survival\uff0cMFS\uff09\u7684\u4e34\u5e8a\u7ec8\u70b9\u83b7\u6279\u4e0a\u5e02\u7684\u80bf\u7624\u65b0\u836f\u3002<\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;word-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;text-indent: 2em;word-wrap: break-word !important;\">Erleada\u7684\u5b89\u5168\u6027\u53ca\u7597\u6548\u5728\u6d89\u53ca1207\u4f8b\u975e\u8f6c\u79fb\u6027\u53bb\u52bf\u62b5\u6297\u524d\u5217\u817a\u764c\u7684\u968f\u673a\u7814\u7a76\u4e2d\u5f97\u5230\u8bc1\u5b9e\u3002\u60a3\u8005\u968f\u673a\u7ed9\u4e88apalutamide\u6216\u5b89\u6170\u5242\uff0c\u5e76\u63a5\u53d7\u5185\u5206\u6ccc\u6cbb\u7597\uff0c\u5305\u62ec\u63a5\u53d7\u4fc3\u6027\u817a\u6fc0\u7d20\u91ca\u653e\u6fc0\u7d20\uff08GnRH\uff09\u7c7b\u4f3c\u7269\uff0c\u6216\u8005\u624b\u672f\u53bb\u52bf\uff08\u5207\u9664\u53cc\u4fa7\u777e\u4e38\uff09\u4ee5\u964d\u4f4e\u4f53\u5185\u96c4\u6fc0\u7d20\u6c34\u5e73\u3002\u7ed3\u679c\u663e\u793a\uff0capalutamide\u6cbb\u7597\u7ec4\u65e0\u8f6c\u79fb\u751f\u5b58\u671f\u76f8\u6bd4\u5b89\u6170\u5242\u7ec4\u663e\u8457\u5ef6\u957f\uff0840.5 vs 16.2\u4e2a\u6708\uff09\u3002<\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;word-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\"  \/><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"\"  style=\"max-width: 100%;box-sizing: border-box;color: rgb(51, 51, 51);\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<section class=\"\" style=\"padding: 10px;max-width: 100%;box-sizing: border-box;display: inline-block;width: 677px;border-width: 0px 0px 0px 6px;border-style: solid;border-left-color: rgb(36, 96, 178);border-right-color: rgb(36, 96, 178);word-wrap: break-word !important;\">\n<section class=\"\"  style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">05&nbsp;Trogarzo(ibalizumab-uiyk)<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"\"  style=\"max-width: 100%;box-sizing: border-box;color: rgb(51, 51, 51);\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;line-height: 2;word-wrap: break-word !important;\">\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;text-indent: 2em;word-wrap: break-word !important;\">2018\u5e743\u67087\u65e5\uff0c\u7f8e\u56fdFDA\u5ba3\u5e03\u6b63\u5f0f\u6279\u51c6\u836f\u660e\u751f\u7269\u5408\u4f5c\u4f19\u4f34\u4e2d\u88d5\u65b0\u836f(TaiMed)\u7684Trogarzo(ibalizumab-uiyk)\u4e0a\u5e02\uff0c\u4f5c\u4e3a\u4e00\u79cd\u5168\u65b0\u7684\u6297\u9006\u8f6c\u5f55\u75c5\u6bd2\u7597\u6cd5\uff0c\u6cbb\u7597\u73b0\u6709\u591a\u79cd\u7597\u6cd5\u5747\u65e0\u6cd5\u8d77\u6548\u7684\u6210\u4ebaHIV\u611f\u67d3\u8005\u3002\u503c\u5f97\u4e00\u63d0\u7684\u662f\uff0c\u8fd9\u662f\u7f8e\u56fdFDA\u57282018\u5e74\u6279\u51c6\u7684\u9996\u6b3e\u521b\u65b0\u751f\u7269\u836f\uff0c\u6b64\u9879\u76ee\u4e5f\u662f\u836f\u660e\u751f\u7269\u9996\u4e2a\u5546\u4e1a\u5316\u751f\u4ea7\u7684\u9879\u76ee\uff0c\u6807\u5fd7\u7740\u836f\u660e\u751f\u7269\u8dfb\u8eab\u6210\u4e3a\u5168\u7403\u5c11\u6570\u51e0\u4e2a\u901a\u8fc7FDA GMP\u8ba4\u8bc1\u7684\u751f\u7269\u836f\u5408\u4f5c\u7814\u53d1\u751f\u4ea7\u670d\u52a1\u5546(CDMO)\u3002<\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;word-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;text-indent: 2em;word-wrap: break-word !important;\">Trogarzo\u662f\u4e00\u79cd\u9759\u8109\u6ef4\u6ce8\u7684\u4eba\u6e90\u5316\u514d\u75ab\u7403\u86cb\u767dG4\u5355\u514b\u9686\u6297\u4f53\uff0c\u5b83\u4e0eCD4+ T\u7ec6\u80de\u53d7\u4f53\u7684\u7b2c\u4e8c\u4e2a\u80de\u5916\u533a\u57df\u7ed3\u5408\uff0c\u963b\u6b62HIV\u75c5\u6bd2\u5165\u4fb5\u8fd9\u4e9b\u7ec6\u80de\u3002<\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;word-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;text-indent: 2em;word-wrap: break-word !important;\">Trogarzo\u7684\u5b89\u5168\u6027\u4e0e\u7597\u6548\u5728\u4e00\u9879\u4e34\u5e8a\u8bd5\u9a8c\u4e2d\u5f97\u5230\u4e86\u9a8c\u8bc1\u3002\u8be5\u8bd5\u9a8c\u62db\u52df\u4e8640\u540d\u611f\u67d3\u6709\u591a\u91cd\u8010\u836f\u6027HIV\u7684\u60a3\u8005\uff0c\u4ed6\u4eec\u5747\u91cd\u5ea6\u7ecf\u6cbb\uff0c\u6709\u4e9b\u60a3\u8005\u751a\u81f3\u5df2\u7ecf\u63a5\u53d7\u8fc710\u79cd\u6216\u66f4\u591a\u7684\u6297\u9006\u8f6c\u5f55\u75c5\u6bd2\u7597\u6cd5\u3002\u7136\u800c\u5373\u4fbf\u63a5\u53d7\u4e86\u5927\u91cf\u6cbb\u7597\uff0c\u4ed6\u4eec\u8840\u6db2\u4e2d\u7684\u75c5\u6bd2\u6c34\u5e73(HIV-RNA)\u4f9d\u65e7\u5f88\u9ad8\u3002\u7814\u7a76\u4eba\u5458\u53d1\u73b0\uff0c\u5728\u73b0\u6709\u7684\u7597\u6cd5\u4e2d\u989d\u5916\u52a0\u5165Trogarzo\u7684\u6cbb\u7597\u540e\uff0c\u53ea\u8981\u77ed\u77ed\u4e00\u5468\uff0c\u5927\u90e8\u5206\u60a3\u8005\u8840\u6db2\u4e2d\u7684HIV-RNA\u6c34\u5e73\u5c31\u6709\u663e\u8457\u4e0b\u964d\u300224\u5468\u540e\uff0c43%\u7684\u60a3\u8005\u5176HIV-RNA\u6c34\u5e73\u4f9d\u65e7\u5f97\u5230\u4e86\u6291\u5236\u3002\u5bf9\u4e8e\u8fd9\u4e9b\u6025\u7f3a\u6cbb\u7597\u65b9\u6848\u7684\u60a3\u8005\uff0cTrogarzo\u5e26\u6765\u4e86\u663e\u8457\u76ca\u5904\u3002<\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;word-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\"  \/><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"\"  style=\"max-width: 100%;box-sizing: border-box;color: rgb(51, 51, 51);\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<section class=\"\" style=\"padding: 10px;max-width: 100%;box-sizing: border-box;display: inline-block;width: 677px;border-width: 0px 0px 0px 6px;border-style: solid;border-left-color: rgb(36, 96, 178);border-right-color: rgb(36, 96, 178);word-wrap: break-word !important;\">\n<section class=\"\"  style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">06&nbsp;Ilumya(ibalizumab-uiyk)<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"\"  style=\"max-width: 100%;box-sizing: border-box;color: rgb(51, 51, 51);\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;line-height: 2;word-wrap: break-word !important;\">\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;text-indent: 2em;word-wrap: break-word !important;\">3\u670820\u65e5\uff0cFDA\u6279\u51c6ILUMYA \uff08tildrakizumab-asmn\uff09\u4e0a\u5e02\uff0c\u7528\u4e8e\u9002\u5408\u63a5\u53d7\u5168\u8eab\u6cbb\u7597\u6216\u5149\u7597\u7684\u4e2d\u91cd\u5ea6\u6591\u5757\u578b\u94f6\u5c51\u75c5\u6210\u4eba\u60a3\u8005\u3002<\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;word-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;text-indent: 2em;word-wrap: break-word !important;\">\u636e3\u671f\u4e34\u5e8a\u8bd5\u9a8c\u6570\u636e\u663e\u793a\uff0c\u4e0e\u5b89\u6170\u5242\u76f8\u6bd4\uff0c\u65bd\u7528ILUMYA 100 mg\u80fd\u53d6\u5f97\u663e\u8457\u7684\u4e34\u5e8a\u6539\u5584\u3002\u7814\u7a76\u901a\u8fc7\u4e24\u6b21\u7528\u836f\u540e\u7b2c12\u5468\u81f3\u5c1175%\u7684\u76ae\u80a4\u6e05\u9664\u7387\uff08\u94f6\u5c51\u75c5\u9762\u79ef\u654f\u611f\u6307\u6570\u6216PASI 75\uff09\uff0c\u4ee5\u53ca\u533b\u5e08\u5168\u9762\u8bc4\u4f30\uff08PGA\uff09\u8bc4\u5206\u201c\u6e05\u9664\u201d\u6216\u201c\u6700\u5c0f\u201d\u8fdb\u884c\u6d4b\u91cf\u3002\u5176\u4e2d\uff0c\u8be5\u7814\u7a76\u670974%\uff08229\u4eba\uff09\u7684\u60a3\u8005\u5728\u4e09\u6b21\u7528\u836f\u540e\u7b2c28\u5468\u8fbe\u523075%\u7684\u76ae\u80a4\u6e05\u9664\u7387\uff0c84%\u6301\u7eed\u7528\u836f\u7684\u60a3\u8005\u5728\u7b2c64\u5468\u80fd\u7ef4\u6301PASI 75\u3002\u6bcb\u5eb8\u7f6e\u7591\uff0cILUMYA\u662f\u4e2d\u5ea6\u81f3\u91cd\u5ea6\u6591\u5757\u578b\u94f6\u5c51\u75c5\u4e34\u5e8a\u6cbb\u7597\u4e0a\u7684\u53c8\u4e00\u4e2a\u91cd\u8981\u7a81\u7834\u3002<\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;text-indent: 2em;word-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\"  \/><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"\"  style=\"max-width: 100%;box-sizing: border-box;color: rgb(51, 51, 51);\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<section class=\"\" style=\"padding: 10px;max-width: 100%;box-sizing: border-box;display: inline-block;width: 677px;border-width: 0px 0px 0px 6px;border-style: solid;border-left-color: rgb(36, 96, 178);border-right-color: rgb(36, 96, 178);word-wrap: break-word !important;\">\n<section class=\"\"  style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;word-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">07 Tavalisse(fostamatinib\uff09<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"\"  style=\"max-width: 100%;box-sizing: border-box;color: rgb(51, 51, 51);\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;line-height: 2;word-wrap: break-word !important;\">\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;text-indent: 2em;word-wrap: break-word !important;\">4\u670817\u65e5\uff0c\u7f8e\u56fdFDA\u6279\u51c6\u4e86Rigel\u5236\u836f\u7684TAVALISSE\u7528\u4e8e\u5bf9\u4e4b\u524d\u6cbb\u7597\u7f13\u89e3\u4e0d\u4f73\u7684\u6210\u5e74\u6162\u6027\u514d\u75ab\u6027\u8840\u5c0f\u677f\u51cf\u5c11\u75c7\uff08ITP\uff09\u60a3\u8005\u8840\u5c0f\u677f\u51cf\u5c11\u7684\u6cbb\u7597\u3002TAVALISSE\u662f\u4e00\u79cd\u53e3\u670d\u7684\u813e\u810f\u916a\u6c28\u9178\u6fc0\u9176(SYK)\u6291\u5236\u5242\uff0c\u901a\u8fc7\u963b\u6b62\u8840\u5c0f\u677f\u7684\u7834\u574f\u6765\u5e94\u5bf9\u75be\u75c5\u7684\u6f5c\u5728\u81ea\u8eab\u514d\u75ab\u539f\u56e0\uff0c\u4e3a\u6210\u5e74\u6162\u6027ITP\u60a3\u8005\u63d0\u4f9b\u4e86\u4e00\u4e2a\u91cd\u8981\u7684\u65b0\u7684\u6cbb\u7597\u65b9\u6848\u3002<\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;word-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;text-indent: 2em;word-wrap: break-word !important;\">TAVALISSE\u7684\u6279\u51c6\u4f9d\u8d56\u4e8eFIT\u4e34\u5e8a\u7814\u7a76\u9879\u76ee\u7684\u6570\u636e\uff0cFIT\u5305\u542b\u4e24\u9879\u968f\u673a\u5b89\u6170\u5242\u5bf9\u7167\u7684\u4e34\u5e8a3\u671f\u7814\u7a76047\u548c048\u3001\u4e00\u9879\u5f00\u6807\u6269\u5c55\u8bd5\u9a8c049\u4ee5\u53ca\u6700\u521d\u7684\u6982\u5ff5\u9a8c\u8bc1\u8bd5\u9a8c\u3002\u65b0\u836f\u4e0a\u5e02\u7533\u8bf7\u5305\u62ec\u4e86163\u4f8bITP\u60a3\u8005\u7684\u6570\u636e\uff0c\u5e76\u5f97\u5230\u4e86\u4e00\u9879\u5b89\u5168\u6570\u636e\u96c6\u7684\u652f\u6301\uff0c\u8be5\u6570\u636e\u96c6\u5305\u542b4600\u591a\u540d\u6d89\u53ca\u5176\u5b83\u9002\u5e94\u75c7\u7684\u5df2\u63a5\u53d7TAVALISSE\u8bc4\u4f30\u7684\u53d7\u8bd5\u8005\u3002<\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;text-indent: 2em;word-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\"  \/><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"\"  style=\"max-width: 100%;box-sizing: border-box;color: rgb(51, 51, 51);\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<section class=\"\" style=\"padding: 10px;max-width: 100%;box-sizing: border-box;display: inline-block;width: 677px;border-width: 0px 0px 0px 6px;border-style: solid;border-left-color: rgb(36, 96, 178);border-right-color: rgb(36, 96, 178);word-wrap: break-word !important;\">\n<section class=\"\"  style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;word-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">08 Crysvita(burosumab-twza)<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"\"  style=\"max-width: 100%;box-sizing: border-box;color: rgb(51, 51, 51);\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;line-height: 2;word-wrap: break-word !important;\">\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;text-indent: 2em;word-wrap: break-word !important;\">4\u670817\u65e5\uff0c\u7f8e\u56fdFDA\u6279\u51c6\u4e86Ultragenyx Pharmaceutical\u516c\u53f8\u7684\u65b0\u836fCrysvita\uff0c\u6210\u4e3a\u9996\u4e2a\u83b7\u6279\u6cbb\u75971\u5c81\u53ca\u4ee5\u4e0a\u513f\u7ae5\u548c\u6210\u5e74\u4eba\u7684X\u8fde\u9501\u4f4e\u78f7\u8840\u75c7\uff08XLH\uff09\u7684\u836f\u7269\u3002XLH\u662f\u4e00\u79cd\u7f55\u89c1\u7684\u9057\u4f20\u6027\u8f6f\u9aa8\u75c5\uff0c\u4f1a\u9020\u6210\u8840\u6db2\u4e2d\u78f7\u542b\u91cf\u4f4e\uff0c\u5bfc\u81f4\u513f\u7ae5\u548c\u9752\u5c11\u5e74\u7684\u9aa8\u9abc\u751f\u957f\u548c\u53d1\u80b2\u53d7\u635f\uff0c\u5e76\u4f7f\u5176\u4e00\u751f\u90fd\u6709\u9aa8\u77ff\u5316\u7684\u95ee\u9898\u3002<\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;word-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;text-indent: 2em;word-wrap: break-word !important;\">&nbsp;Crysvita\u83b7\u6279\u662f\u57fa\u4e8e4\u9879\u4e34\u5e8a\u8bd5\u9a8c\u4e2d\u7684\u5b89\u5168\u6027\u548c\u7597\u6548\u6570\u636e\u3002\u5728\u4e00\u9879\u5b89\u6170\u5242\u5bf9\u7167\u4e34\u5e8a\u8bd5\u9a8c\u4e2d\uff0c94\uff05\u7684\u6bcf\u6708\u63a5\u53d7\u4e00\u6b21Crysvita\u7684\u6210\u5e74\u4eba\u80fd\u8fbe\u5230\u6b63\u5e38\u7684\u78f7\u6c34\u5e73\uff0c\u800c\u5b89\u6170\u5242\u7ec4\u60a3\u8005\u53ea\u67098\uff05\u80fd\u8fbe\u5230\u8fd9\u4e00\u6c34\u5e73\u3002\u5728\u513f\u7ae5\u4e2d\uff0c\u6bcf\u4e24\u5468\u63a5\u53d7\u4e00\u6b21Crysvita\u7684\u60a3\u8005\u4e2d\u670994\uff05\u5230100\uff05\u80fd\u8fbe\u5230\u6b63\u5e38\u7684\u78f7\u6c34\u5e73\u3002\u5728\u513f\u7ae5\u548c\u6210\u4eba\u4e2d\uff0c\u63a5\u53d7Crysvita\u7597\u6cd5\u7684\u60a3\u8005\u7684X\u5149\uff08\u4e0eXLH\u76f8\u5173\uff09\u7ed3\u679c\u6709\u6240\u6539\u5584\u3002\u628a\u8fd9\u4e9b\u7ed3\u679c\u4e0e\u81ea\u7136\u5386\u53f2\u961f\u5217\u76f8\u6bd4\u8f83\uff0c\u4e5f\u4e3aCrysvita\u7684\u6709\u6548\u6027\u63d0\u4f9b\u4e86\u652f\u6301\u3002<\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;word-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\"  \/><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"\"  style=\"max-width: 100%;box-sizing: border-box;color: rgb(51, 51, 51);\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<section class=\"\" style=\"padding: 10px;max-width: 100%;box-sizing: border-box;display: inline-block;width: 677px;border-width: 0px 0px 0px 6px;border-style: solid;border-left-color: rgb(36, 96, 178);border-right-color: rgb(36, 96, 178);word-wrap: break-word !important;\">\n<section class=\"\"  style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">09&nbsp;Akynzeo \uff08fosnetupitant&nbsp;<\/strong><\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">and palonosetron\uff09<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"\"  style=\"max-width: 100%;box-sizing: border-box;color: rgb(51, 51, 51);\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;line-height: 2;word-wrap: break-word !important;\">\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;text-indent: 2em;word-wrap: break-word !important;\">4\u670819\u65e5\uff0cFDA\u6279\u51c6\u4e86\u745e\u58eb\u5236\u836f\u96c6\u56e2Helsinn\u516c\u53f8\u7684\u9759\u8109\u6ce8\u5c04AKYNZEO\uff0c\u4f5c\u4e3a\u7ecf\u5386CINV\u7684\u60a3\u8005\u7684\u66ff\u4ee3\u6cbb\u7597\u9009\u62e9\u3002<\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;word-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;text-indent: 2em;word-wrap: break-word !important;\">FDA\u5df2\u6279\u51c6\u5c06AKYNZEO\u00aeIV\u4e0e\u6210\u4eba\u5730\u585e\u7c73\u677e\u8054\u5408\u7528\u4e8e\u9884\u9632\u4e0e\u9ad8\u5ea6\u81f4\u5410\u6027\u764c\u75c7\u5316\u7597\u7684\u521d\u59cb\u548c\u91cd\u590d\u8fc7\u7a0b\u6709\u5173\u7684\u6025\u6027\u548c\u5ef6\u8fdf\u6027\u6076\u5fc3\u548c\u5455\u5410\u3002\u5c1a\u672a\u7814\u7a76AKYNZEO\u00ae\u7528\u4e8e\u9884\u9632\u4e0e\u84bd\u73af\u7c7b\u52a0\u73af\u78f7\u9170\u80fa\u5316\u7597\u76f8\u5173\u7684\u6076\u5fc3\u548c\u5455\u5410<\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;word-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;text-indent: 2em;word-wrap: break-word !important;\">\u53e3\u670dAKYNZEO\u57282014\u5e74\u88ab\u7f8e\u56fd\u98df\u54c1\u836f\u7269\u7ba1\u7406\u5c40\u6279\u51c6\u4e3a\u56fa\u5b9a\u7ec4\u5408\u53e3\u670d\u836f\uff0c\u7528\u4e8e\u9884\u9632\u4e0e\u764c\u75c7\u5316\u7597\u521d\u671f\u548c\u91cd\u590d\u8fc7\u7a0b\u6709\u5173\u7684\u6025\u6027\u548c\u5ef6\u8fdf\u6027\u6076\u5fc3\u548c\u5455\u5410\uff0c\u5305\u62ec\u4f46\u4e0d\u9650\u4e8e\u9ad8\u5ea6\u81f4\u5410\u5316\u7597\u3002<\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;word-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;text-indent: 2em;word-wrap: break-word !important;\">AKYNZEO\u00ae\u9759\u8109\u6ce8\u5c04\u5236\u5242\u7684\u6279\u51c6\u4e3a\u5c06\u8fd9\u79cd\u91cd\u8981\u6cbb\u7597\u9009\u62e9\u5e26\u5165\u66f4\u591a\u60a3\u8005\u91c7\u7528\u65b0\u914d\u65b9\u94fa\u5e73\u4e86\u9053\u8def\uff0c\u5e76\u5c06\u4e8e2018\u5e745\u6708\u5728\u7f8e\u56fd\u63a8\u51fa\u6b64\u4ea7\u54c1\u3002<\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;text-indent: 2em;word-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\"  \/><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"\"  style=\"max-width: 100%;box-sizing: border-box;color: rgb(51, 51, 51);\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<section class=\"\" style=\"padding: 10px;max-width: 100%;box-sizing: border-box;display: inline-block;width: 677px;border-width: 0px 0px 0px 6px;border-style: solid;border-left-color: rgb(36, 96, 178);border-right-color: rgb(36, 96, 178);word-wrap: break-word !important;\">\n<section class=\"\"  style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box;letter-spacing: 0px;line-height: 1.6;word-wrap: break-word !important;\">10 Lucemyra&nbsp;<\/strong><\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box;letter-spacing: 0px;line-height: 1.6;word-wrap: break-word !important;\">\uff08ofexidine hydrochloride\uff09<\/strong><br style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\"  \/><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"\"  style=\"max-width: 100%;box-sizing: border-box;color: rgb(51, 51, 51);\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;line-height: 2;word-wrap: break-word !important;\">\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;text-indent: 2em;word-wrap: break-word !important;\">5\u670816\u65e5\uff0c\u7f8e\u56fdFDA\u5ba3\u5e03\u6279\u51c6US WorldMeds\u7684Lucemyra\uff08\u76d0\u9178\u6d1b\u975e\u65af\u6c40\uff0clofexidine hydrochloride\uff09\uff0c\u7528\u4e8e\u7f13\u89e3\u7a81\u7136\u505c\u7528\u963f\u7247\u7c7b\u836f\u7269\u7684\u6210\u4eba\u60a3\u8005\u7684\u6212\u65ad\u75c7\u72b6\u3002\u867d\u7136Lucemyra\u53ef\u4ee5\u51cf\u8f7b\u6212\u65ad\u75c7\u72b6\u7684\u4e25\u91cd\u7a0b\u5ea6\uff0c\u4f46\u5b83\u65e0\u6cd5\u5b8c\u5168\u963b\u6b62\u8fd9\u4e9b\u75c7\u72b6\uff0c\u5e76\u4e14\u6700\u957f\u53ea\u80fd\u4f7f\u752814\u5929\u3002<\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;word-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;text-indent: 2em;word-wrap: break-word !important;\">Lucemyra\u7684\u5b89\u5168\u6027\u548c\u6709\u6548\u6027\u5f97\u5230\u4e86\u4e24\u9879\u968f\u673a\u3001\u53cc\u76f2\u3001\u5b89\u6170\u5242\u5bf9\u7167\u4e34\u5e8a\u8bd5\u9a8c\u7684\u652f\u6301\u3002\u8fd9\u4e9b\u4e34\u5e8a\u8bd5\u9a8c\u5171\u6709866\u540d\u7b26\u5408\u963f\u7247\u7c7b\u836f\u7269\u4f9d\u8d56\u8bca\u65ad\u6807\u51c6\u7684\u6210\u4eba\u60a3\u8005\uff0c\u8fd9\u4e9b\u60a3\u8005\u5728\u751f\u7406\u4e0a\u4f9d\u8d56\u4e8e\u963f\u7247\u7c7b\u836f\u7269\uff0c\u5e76\u6b63\u5728\u8fdb\u884c\u963f\u7247\u7c7b\u836f\u7269\u6212\u65ad\u3002\u8fd9\u4e9b\u7814\u7a76\u4f7f\u7528Gossop\u77ed\u6682\u505c\u836f\u91cf\u8868\uff08SOWS-Gossop\uff09\u6765\u8bc4\u4f30\u7597\u6548\uff0c\u8fd9\u662f\u4e00\u79cd\u901a\u8fc7\u60a3\u8005\u62a5\u544a\u7ed3\u679c\u6765\u8bc4\u4f30\u963f\u7247\u7c7b\u6212\u65ad\u75c7\u72b6\u7684\u5de5\u5177\u3002\u8fd9\u4e9b\u75c7\u72b6\u5305\u62ec\u611f\u89c9\u4e0d\u9002\u3001\u80c3\u75c9\u631b\u3001\u62bd\u6410\u3001\u611f\u89c9\u51b7\u3001\u5fc3\u810f\u5267\u70c8\u8df3\u52a8\u3001\u808c\u8089\u7d27\u5f20\u3001\u75bc\u75db\uff0c\u6253\u5475\u6b20\u3001\u6d41\u6cea\u548c\u5931\u7720\u3002<\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;word-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\"  \/><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"\"  style=\"max-width: 100%;box-sizing: border-box;color: rgb(51, 51, 51);\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<section class=\"\" style=\"padding: 10px;max-width: 100%;box-sizing: border-box;display: inline-block;width: 677px;border-width: 0px 0px 0px 6px;border-style: solid;border-left-color: rgb(36, 96, 178);border-right-color: rgb(36, 96, 178);word-wrap: break-word !important;\">\n<section class=\"\"  style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">11 Aimovig(erenumab-aooe)<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"\"  style=\"max-width: 100%;box-sizing: border-box;color: rgb(51, 51, 51);\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;line-height: 2;word-wrap: break-word !important;\">\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;text-indent: 2em;word-wrap: break-word !important;\">5\u670817\u65e5\uff0cFDA\u6279\u51c6\u4e86\u5b89\u8fdb\uff08Amgen\uff09\u516c\u53f8\u7684Aimovig\uff0c\u4f5c\u4e3a\u6210\u4eba\u504f\u5934\u75db\u7684\u9884\u9632\u6027\u6cbb\u7597\uff0c\u7ed9\u836f\u65b9\u5f0f\u4e3a\u6bcf\u6708\u4e00\u6b21\u7684\u81ea\u6211\u6ce8\u5c04\uff0c\u8fd9\u4e5f\u662fFDA\u6279\u51c6\u7684\u9996\u4e2a\u9884\u9632\u6027\u504f\u5934\u75db\u6cbb\u7597\u836f\u7269\u3002<\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;word-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;text-indent: 2em;word-wrap: break-word !important;\">Aimovig\u83b7\u6279\u4e3b\u8981\u57fa\u4e8e\u56f4\u7ed5\u5176\u5c55\u5f00\u7684\u4e09\u9879\u4e34\u5e8a\u8bd5\u9a8c\uff0c\u8bd5\u9a8c\u8bc4\u4f30\u4e86\u5176\u5728\u504f\u5934\u75db\u9884\u9632\u4e2d\u7684\u5b89\u5168\u6027\u548c\u6709\u6548\u6027\u3002<\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;word-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;text-indent: 2em;word-wrap: break-word !important;\">\u7b2c\u4e00\u9879\u7814\u7a76\u5305\u62ec955\u540d\u6709\u53d1\u4f5c\u6027\u504f\u5934\u75db\u75c5\u53f2\u7684\u53c2\u4e0e\u8005\uff0c\u5e76\u5c06Aimovig\u4e0e\u5b89\u6170\u5242\u8fdb\u884c\u6bd4\u8f83\u3002\u57286\u4e2a\u6708\u7684\u65f6\u95f4\u91cc\uff0caimovig\u6cbb\u7597\u7684\u60a3\u8005\u5e73\u5747\u6bcf\u6708\u7684\u504f\u5934\u75db\u5929\u6570\u6bd4\u670d\u7528\u5b89\u6170\u5242\u7684\u60a3\u8005\u5c111\u52302\u4e2a\u6708\u3002<\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;word-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;text-indent: 2em;word-wrap: break-word !important;\">\u7b2c\u4e8c\u9879\u7814\u7a76\u5305\u62ec577\u540d\u6709\u53d1\u4f5c\u6027\u504f\u5934\u75db\u75c5\u53f2\u7684\u60a3\u8005\uff0c\u5e76\u5c06Aimovig\u4e0e\u5b89\u6170\u5242\u8fdb\u884c\u6bd4\u8f83\u3002\u5728\u4e09\u4e2a\u6708\u7684\u65f6\u95f4\u91cc\uff0caimovig\u6cbb\u7597\u7684\u60a3\u8005\u5e73\u5747\u6bcf\u4e2a\u6708\u6bd4\u670d\u7528\u5b89\u6170\u5242\u7684\u75c5\u4eba\u5c11\u4e00\u6b21\u504f\u5934\u75db\u3002<\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;word-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;text-indent: 2em;word-wrap: break-word !important;\">\u7b2c\u4e09\u9879\u7814\u7a76\u5bf9667\u4f8b\u6162\u6027\u504f\u5934\u75db\u60a3\u8005\u8fdb\u884c\u4e86\u8bc4\u4f30\uff0c\u5e76\u5c06Aimovig\u4e0e\u5b89\u6170\u5242\u8fdb\u884c\u6bd4\u8f83\u3002\u5728\u8fd9\u9879\u7814\u7a76\u4e2d\uff0c\u5728\u4e09\u4e2a\u6708\u7684\u65f6\u95f4\u91cc\uff0c\u63a5\u53d7Aimovig\u6cbb\u7597\u7684\u60a3\u8005\u5e73\u5747\u6bcf\u6708\u6bd4\u63a5\u53d7\u5b89\u6170\u5242\u7684\u60a3\u8005\u5c112\u6b21\u3002\u4e34\u5e8a\u8bd5\u9a8c\u4e2d\u6700\u5e38\u89c1\u7684\u526f\u4f5c\u7528\u662f\u6ce8\u5c04\u90e8\u4f4d\u7684\u53cd\u5e94\u548c\u4fbf\u79d8\u3002<\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;word-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\"  \/><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"\"  style=\"max-width: 100%;box-sizing: border-box;color: rgb(51, 51, 51);\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<section class=\"\" style=\"padding: 10px;max-width: 100%;box-sizing: border-box;display: inline-block;width: 677px;border-width: 0px 0px 0px 6px;border-style: solid;border-left-color: rgb(36, 96, 178);border-right-color: rgb(36, 96, 178);word-wrap: break-word !important;\">\n<section class=\"\"  style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">12 Lokelma \uff08sodium zirconium cyclosilicate\uff09<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"\"  style=\"max-width: 100%;box-sizing: border-box;color: rgb(51, 51, 51);\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;line-height: 2;word-wrap: break-word !important;\">\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;text-indent: 2em;word-wrap: break-word !important;\">5\u670818\u65e5\uff0c\u7f8e\u56fdFDA\u6279\u51c6\u4e86\u963f\u65af\u5229\u5eb7\uff08AstraZeneca\uff09\u7684\u65b0\u836fLokelma\u7528\u4e8e\u6cbb\u7597\u7f79\u60a3\u9ad8\u94be\u8840\u75c7\uff08hyperkalaemia\uff09\u7684\u6210\u4eba\u60a3\u8005\u3002<\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;word-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;text-indent: 2em;word-wrap: break-word !important;\">\u9ad8\u8840\u94be\u98ce\u9669\u5728\u6162\u6027\u80be\u75c5\uff08CKD\uff09\u60a3\u8005\u4ee5\u53ca\u670d\u7528\u666e\u901a\u5fc3\u529b\u8870\u7aed\uff08HF\uff09\u836f\u7269\uff08\u5982\u80be\u7d20-\u8840\u7ba1\u7d27\u5f20\u7d20-\u919b\u56fa\u916e\u7cfb\u7edf[RAAS]\u6291\u5236\u5242\uff09\u7684\u60a3\u8005\u4e2d\u663e\u8457\u589e\u52a0\uff0c\u56e0\u4e3a\u8fd9\u79cd\u836f\u7269\u4f1a\u589e\u52a0\u8840\u94be\u6c34\u5e73\u3002<\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;word-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;text-indent: 2em;word-wrap: break-word !important;\">Lokelma\u4e8e\u4eca\u5e743\u6708\u5e95\u5728\u6b27\u76df\u83b7\u6279\u4e0a\u5e02\u3002\u6b21Lokelma\u83b7\u5f97FDA\u7684\u6279\u51c6\u662f\u57fa\u4e8e\u4e09\u9879\u53cc\u76f2\u3001\u5b89\u6170\u5242\u5bf9\u7167\u8bd5\u9a8c\u548c\u4e24\u9879\u5f00\u653e\u6807\u7b7e\u8bd5\u9a8c\u6570\u636e\u7684\u652f\u6301\u3002<\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;word-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;text-indent: 2em;word-wrap: break-word !important;\">\u8fd9\u4e9b\u7814\u7a76\u8868\u660e\uff0cLokelma\u7684\u8d77\u6548\u65f6\u95f4\u662f\u670d\u836f\u540e1.0\u5c0f\u65f6\uff0c\u8fbe\u5230\u6b63\u5e38\u8840\u94be\u6c34\u5e73\u7684\u4e2d\u4f4d\u65f6\u95f4\u662f2.2\u5c0f\u65f6\uff0c92\uff05\u7684\u60a3\u8005\u5728\u57fa\u7ebf\u540e48\u5c0f\u65f6\u5185\u8fbe\u5230\u6b63\u5e38\u8840\u94be\u6c34\u5e73\u3002\u8be5\u836f\u7269\u7684\u6cbb\u7597\u6548\u679c\u53ef\u7ef4\u6301\u957f\u8fbe12\u4e2a\u6708\u3002<\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;text-indent: 2em;word-wrap: break-word !important;\">&nbsp;<\/p>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"\"  style=\"max-width: 100%;box-sizing: border-box;color: rgb(51, 51, 51);\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<section class=\"\" style=\"padding: 10px;max-width: 100%;box-sizing: border-box;display: inline-block;width: 677px;border-width: 0px 0px 0px 6px;border-style: solid;border-left-color: rgb(36, 96, 178);border-right-color: rgb(36, 96, 178);word-wrap: break-word !important;\">\n<section class=\"\"  style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\">13 Doptelet(avatrombopag)<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"\"  style=\"max-width: 100%;box-sizing: border-box;color: rgb(51, 51, 51);\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;line-height: 2;word-wrap: break-word !important;\">\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;text-indent: 2em;word-wrap: break-word !important;\">&nbsp;5\u670821\u65e5\uff0c\u7f8e\u56fdFDA\u6279\u51c6Dova Pharmaceuticals\u5b50\u516c\u53f8AkaRx\u7684\u65b0\u836fDoptelet\u7247\u5242\uff0c\u7528\u4e8e\u6cbb\u7597\u8ba1\u5212\u63a5\u53d7\u533b\u7597\u6216\u7259\u79d1\u624b\u672f\u7684\u6162\u6027\u809d\u75c5\uff08CLD\uff09\u6210\u4eba\u60a3\u8005\u7684\u4f4e\u8840\u5c0f\u677f\u8ba1\u6570\uff08\u8840\u5c0f\u677f\u51cf\u5c11\u75c7\uff09\u3002<\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;word-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;text-indent: 2em;word-wrap: break-word !important;\">Doptelet\u7684\u5b89\u5168\u6027\u548c\u6709\u6548\u6027\u5728\u4e24\u9879\u8bd5\u9a8c\uff08ADAPT-1\u548cADAPT-2\uff09\u4e2d\u5f97\u5230\u4e86\u9a8c\u8bc1\u3002\u8fd9\u4e9b\u7814\u7a76\u5171\u5305\u542b435\u540d\u6162\u6027\u809d\u75c5\u548c\u4e25\u91cd\u8840\u5c0f\u677f\u51cf\u5c11\u75c7\u60a3\u8005\uff0c\u4ed6\u4eec\u5c06\u63a5\u53d7\u901a\u5e38\u9700\u8981\u8f93\u6ce8\u8840\u5c0f\u677f\u7684\u624b\u672f\u3002\u8fd9\u4e9b\u8bd5\u9a8c\u8bc4\u4f30\u4e86\u4e24\u4e2a\u5242\u91cf\u6c34\u5e73\u7684\u53e3\u670dDoptelet\u4e0e\u5b89\u6170\u5242\u76f8\u6bd4\u6cbb\u75975\u5929\u7684\u6548\u679c\u3002\u7ed3\u679c\u663e\u793a\uff0c\u4e0e\u5b89\u6170\u5242\u7ec4\u76f8\u6bd4\uff0c\u4e24\u79cd\u5242\u91cf\u6c34\u5e73\u7684Doptelet\u7ec4\u6709\u8f83\u9ad8\u6bd4\u4f8b\u7684\u60a3\u8005\u5177\u6709\u589e\u52a0\u7684\u8840\u5c0f\u677f\u8ba1\u6570\uff0c\u5e76\u4e14\u4e0d\u9700\u8981\u5728\u624b\u672f\u5f53\u5929\u548c\u6cbb\u7597\u540e7\u5929\u5185\u63a5\u53d7\u8840\u5c0f\u677f\u8f93\u6ce8\u6216\u4efb\u4f55\u6551\u63f4\u6cbb\u7597\u3002Doptelet\u6700\u5e38\u89c1\u7684\u526f\u4f5c\u7528\u6709\u53d1\u70e7\u3001\u80c3\uff08\u8179\uff09\u75db\u3001\u6076\u5fc3\u3001\u5934\u75db\u3001\u75b2\u52b3\u548c\u624b\u8db3\u80bf\u80c0\uff08\u6c34\u80bf\uff09\u3002<\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;word-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\"  \/><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"\"  style=\"max-width: 100%;box-sizing: border-box;color: rgb(51, 51, 51);\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<section class=\"\" style=\"padding: 10px;max-width: 100%;box-sizing: border-box;display: inline-block;width: 677px;border-width: 0px 0px 0px 6px;border-style: solid;border-left-color: rgb(36, 96, 178);border-right-color: rgb(36, 96, 178);word-wrap: break-word !important;\">\n<section class=\"\"  style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">14 Doptelet(avatrombopag)<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"\"  style=\"max-width: 100%;box-sizing: border-box;color: rgb(51, 51, 51);\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;line-height: 2;word-wrap: break-word !important;\">\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;text-indent: 2em;word-wrap: break-word !important;\">5\u670824\u65e5\uff0cFDA\u6279\u51c6\u4e86BioMarin Pharmaceutical\u516c\u53f8\u7684Palynziq\u6ce8\u5c04\u5242\uff0c\u7528\u4e8e\u964d\u4f4e\u82ef\u4e19\u916e\u5c3f\u75c7\uff08PKU\uff09\u6210\u4eba\u60a3\u8005\u7684\u8840\u6db2\u82ef\u4e19\u6c28\u9178\uff08Phe\uff09\u6c34\u5e73 \uff0c\u8fd9\u4e9b\u60a3\u8005\u5728\u73b0\u6709\u7ba1\u7406\u4e0b\u5176\u8840\u6db2Phe\u6d53\u5ea6\u65e0\u6cd5\u63a7\u5236\u5728600\u5fae\u6469\u5c14\/\u5347\u4ee5\u5185\u3002<\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;word-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;text-indent: 2em;word-wrap: break-word !important;\">Palynziq\u662f\u4e00\u79cd\u805a\u4e59\u4e8c\u9187\u5316\u7684\u91cd\u7ec4\u82ef\u4e19\u6c28\u9178\u89e3\u6c28\u9176\uff0c\u7528\u6765\u66ff\u4ee3PKU\u60a3\u8005\u7f3a\u4e4f\u7684\u82ef\u4e19\u6c28\u9178\u7f9f\u5316\u9176\uff08PAH\uff09\u4ee5\u5206\u89e3Phe\u3002\u5728\u5173\u952e3\u671f\u7814\u7a76PRISM-2\u4e2d\uff0cPalynziq\u4e0e\u5b89\u6170\u5242\u76f8\u6bd4\u663e\u8457\u964d\u4f4e\u4e86\u8840\u6db2Phe\u6c34\u5e73\uff08p&lt;0.0001\uff09\uff0c\u62b5\u8fbe\u4e86\u8840\u6db2Phe\u53d8\u5316\u7684\u4e3b\u8981\u7ec8\u70b9\u3002\u5728PRISM-2\u53cc\u76f2\u3001\u5b89\u6170\u5242\u5bf9\u7167\u3001\u968f\u673a\u505c\u836f\u671f\u8bd5\u9a8c\uff08RWP\uff09\u4e2d\uff0c\u60a3\u8005\u4ee52\uff1a1\u7684\u6bd4\u4f8b\u88ab\u968f\u673a\u5206\u914d\u7ee7\u7eed\u63a5\u53d7Palynziq\u6cbb\u7597\uff08\u6bcf\u65e520 mg\u6216\u6bcf\u65e540 mg\uff09\u6216\u63a5\u53d7\u5b89\u6170\u5242\uff0c\u6301\u7eed8\u5468\u3002\u7ed3\u679c\u663e\u793a\uff0cPalynziq\u7ec4\u60a3\u8005\u53ef\u4ee5\u7ef4\u6301\u8840\u6db2Phe\u6d53\u5ea6\uff0c\u800c\u5b89\u6170\u5242\u7ec4\u60a3\u8005\u7684\u8840\u6db2Phe\u6d53\u5ea6\u6062\u590d\u5230\u6cbb\u7597\u524d\u57fa\u7ebf\u3002<\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;word-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\"  \/><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"\"  style=\"max-width: 100%;box-sizing: border-box;color: rgb(51, 51, 51);\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<section class=\"\" style=\"padding: 10px;max-width: 100%;box-sizing: border-box;display: inline-block;width: 677px;border-width: 0px 0px 0px 6px;border-style: solid;border-left-color: rgb(36, 96, 178);border-right-color: rgb(36, 96, 178);word-wrap: break-word !important;\">\n<section class=\"\"  style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">15&nbsp;Olumiant(baricitinib)<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"\"  style=\"max-width: 100%;box-sizing: border-box;color: rgb(51, 51, 51);\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;line-height: 2;word-wrap: break-word !important;\">\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;text-indent: 2em;word-wrap: break-word !important;\">5\u670831\u65e5\uff0c\u7f8e\u56fdFDA\u6279\u51c6\u4e86\u793c\u6765\u516c\u53f8\uff08Eli Lilly\uff09\u65b0\u836fOlumiant\u4e0a\u5e02\uff0c\u6cbb\u7597\u7f79\u60a3\u4e2d\u5ea6\u81f3\u91cd\u5ea6\u7c7b\u98ce\u6e7f\u5173\u8282\u708e\uff0c\u5374\u65e0\u6cd5\u4eceTNF\u6291\u5236\u5242\u6cbb\u7597\u4e2d\u53d7\u76ca\u7684\u6210\u4eba\u60a3\u8005\u3002<\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;word-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;text-indent: 2em;word-wrap: break-word !important;\">\u7531\u793c\u6765\u4e0eIncyte\u5e26\u6765\u7684Olumiant\u5c31\u662f\u8fd9\u6837\u4e00\u6b3e\u5145\u6ee1\u6f5c\u529b\u7684\u65b0\u836f\u3002\u5b83\u662f\u4e00\u6b3e\u6bcf\u65e5\u4e00\u6b21\u7684\u53e3\u670dJAK\u6291\u5236\u5242\uff0c\u80fd\u9ad8\u6548\u6291\u5236JAK1\u3001JAK2\u3001\u4ee5\u53caTYK2\u3002\u5728\u4eba\u4f53\u5185\uff0c\u4e0d\u5c11\u7ec6\u80de\u56e0\u5b50\u4f9d\u8d56\u4e8eJAK\u7684\u6d3b\u6027\uff0c\u5176\u5728\u4e0d\u5c11\u708e\u6027\u75be\u75c5\u548c\u81ea\u8eab\u514d\u75ab\u75be\u75c5\u7684\u53d1\u75c5\u8fc7\u7a0b\u4e2d\u6709\u6f5c\u5728\u4f5c\u7528\u3002\u901a\u8fc7\u6291\u5236\u591a\u79cdJAK\u7684\u6d3b\u6027\uff0cOlumiant\u6709\u671b\u7ed9\u7c7b\u98ce\u6e7f\u5173\u8282\u708e\u60a3\u8005\u5e26\u6765\u798f\u97f3\u3002<\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;word-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\"  \/><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"\"  style=\"max-width: 100%;box-sizing: border-box;color: rgb(51, 51, 51);\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<section class=\"\" style=\"padding: 10px;max-width: 100%;box-sizing: border-box;display: inline-block;width: 677px;border-width: 0px 0px 0px 6px;border-style: solid;border-left-color: rgb(36, 96, 178);border-right-color: rgb(36, 96, 178);word-wrap: break-word !important;\">\n<section class=\"\"  style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">16&nbsp;Epidioloex (cannabidiol)<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"\"  style=\"max-width: 100%;box-sizing: border-box;color: rgb(51, 51, 51);\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;line-height: 2;word-wrap: break-word !important;\">\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;text-indent: 2em;word-wrap: break-word !important;\">6\u670825\u65e5\uff0c\u7f8e\u56fdFDA\u6279\u51c6\u4e86GW RESEARCH LTD\u65b0\u836fEpidiolex\u53e3\u670d\u6eb6\u6db2\u6cbb\u7597\u4e24\u5c81\u53ca\u4ee5\u4e0a\u60a3\u8005\u7684\u4e24\u79cd\u7f55\u89c1\u548c\u4e25\u91cd\u766b\u75eb\uff0cLennox-Gastaut\u7efc\u5408\u5f81\u548cDravet\u7efc\u5408\u5f81\u76f8\u5173\u7684\u766b\u75eb\u53d1\u4f5c\u3002\u8fd9\u662fFDA\u6279\u51c6\u7684\u7b2c\u4e00\u79cd\u542b\u6709\u4ece\u5927\u9ebb\u4e2d\u63d0\u53d6\u7684\u7eaf\u5316\u836f\u7269\u7684\u836f\u7269\u3002\u8fd9\u4e5f\u662fFDA\u9996\u6b21\u6279\u51c6\u7528\u4e8e\u6cbb\u7597Dravet\u7efc\u5408\u5f81\u60a3\u8005\u7684\u836f\u7269\u3002<\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;word-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;text-indent: 2em;word-wrap: break-word !important;\">\u5728\u4e09\u9879\u968f\u673a\uff0c\u53cc\u76f2\uff0c\u5b89\u6170\u5242\u5bf9\u7167\u7684\u4e34\u5e8a\u8bd5\u9a8c\u4e2d\u7814\u7a76\u4e86Epidiolex\u7684\u6709\u6548\u6027\uff0c\u8be5\u8bd5\u9a8c\u6d89\u53ca516\u540d\u60a3\u6709Lennox-Gastaut\u7efc\u5408\u5f81\u6216Dravet\u7efc\u5408\u5f81\u7684\u60a3\u8005\u3002\u4e0e\u5b89\u6170\u5242\u76f8\u6bd4\uff0cEpidiolex\u4e0e\u5176\u4ed6\u836f\u7269\u4e00\u8d77\u88ab\u8bc1\u660e\u53ef\u6709\u6548\u964d\u4f4e\u766b\u75eb\u53d1\u4f5c\u7684\u9891\u7387\u3002<\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;word-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\"  \/><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"\"  style=\"max-width: 100%;box-sizing: border-box;color: rgb(51, 51, 51);\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<section class=\"\" style=\"padding: 10px;max-width: 100%;box-sizing: border-box;display: inline-block;width: 677px;border-width: 0px 0px 0px 6px;border-style: solid;border-left-color: rgb(36, 96, 178);border-right-color: rgb(36, 96, 178);word-wrap: break-word !important;\">\n<section class=\"\"  style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">17&nbsp;Zemdri (plazomicin)<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"\"  style=\"max-width: 100%;box-sizing: border-box;color: rgb(51, 51, 51);\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;line-height: 2;word-wrap: break-word !important;\">\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;text-indent: 2em;word-wrap: break-word !important;\">6\u670825\u65e5\uff0c\u7f8e\u56fdFDA\u6279\u51c6\u4e86Achaogen\u65b0\u836fZemdri\u4e0a\u5e02\uff0c\u7528\u4e8e\u7531\u67d0\u4e9b\u80a0\u6746\u83cc\u79d1\u7ec6\u83cc\u611f\u67d3\u5f15\u8d77\u7684\u3001\u6cbb\u7597\u9009\u62e9\u975e\u5e38\u6709\u9650\u6216\u65e0\u6cbb\u7597\u9009\u62e9\u7684\u590d\u6742\u6027\u5c3f\u8def\u611f\u67d3\uff08cUTI\uff0c\u5305\u62ec\u80be\u76c2\u80be\u708e\uff09\u6210\u4eba\u60a3\u8005\uff0c\u8be5\u836f\u662f\u4e00\u79cd\u9759\u8109\u8f93\u6ce8\u836f\u7269\uff0c\u6bcf\u5929\u7ed9\u836f\u4e00\u6b21\u3002<\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;word-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;text-indent: 2em;word-wrap: break-word !important;\">\u6b64\u6b21\u6279\u51c6\uff0c\u4f7fZemdri\u6210\u4e3a\u6cbb\u7597cUTI\u7684\u552f\u4e00\u4e00\u79cd\u6bcf\u65e5\u4e00\u6b21\u7684\u6c28\u57fa\u7cd6\u82f7\u7c7b\u7597\u6cd5\u3002plazomicin\u662f\u4e00\u79cd\u65b0\u4e00\u4ee3\u7684\u6c28\u57fa\u7cd6\u82f7\u7c7b\u6297\u751f\u7d20\uff0c\u80fd\u591f\u6291\u5236\u7ec6\u83cc\u86cb\u767d\u8d28\u7684\u7ffb\u8bd1\u8fc7\u7a0b\u3002plazomicin\u662f\u5728\u897f\u68ad\u9709\u7d20\uff08sisomicin\uff09\u57fa\u7840\u4e0a\u8fdb\u884c\u4e86\u5316\u5b66\u6539\u9020\u800c\u5f97\uff0c\u80fd\u907f\u514d\u88ab\u4e3b\u8981\u7684\u6c28\u57fa\u7cd6\u82f7\u7c7b\u6297\u751f\u7d20\u949d\u5316\u9176\uff08AME\uff09\u7834\u574f\u800c\u5931\u53bb\u6d3b\u6027\u3002plazomicin\u5f00\u53d1\u7528\u4e8e\u6cbb\u7597MDR\u9769\u5170\u6c0f\u9634\u6027\u83cc\u80a0\u6746\u83cc\u79d1\u7ec6\u83cc\u5bfc\u81f4\u7684\u4e25\u91cd\u611f\u67d3\uff0c\u5305\u62ec\u5bf9\u78b3\u9752\u9709\u70ef\u7c7b\u6297\u751f\u7d20\u8010\u836f\u7684\u80a0\u6746\u83cc\u3002<\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;word-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;text-indent: 2em;word-wrap: break-word !important;\">Zemdri\u7684\u83b7\u6279\uff0c\u662f\u57fa\u4e8eIII\u671f\u4e34\u5e8a\u7814\u7a76EPIC\u7684\u6570\u636e\u3002\u8be5\u7814\u7a76\u662f\u9996\u4e2a\u8bc4\u4f30\u6bcf\u65e5\u4e00\u6b21\u6c28\u57fa\u7cd6\u82f7\u7c7b\u7597\u6cd5\u6cbb\u7597cUTI\uff08\u5305\u62ec\u80be\u76c2\u80be\u708e\uff09\u7684\u968f\u673a\u5bf9\u7167\u7814\u7a76\uff0c\u6570\u636e\u663e\u793a\uff0cZemdri\u8fbe\u5230\u4e86\u4e0e\u7f8e\u7f57\u57f9\u5170\uff08meropenem\uff09\u7684\u975e\u52a3\u6548\u6027\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n<p><br  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;color: rgb(102, 102, 102);font-family: \u5fae\u8f6f\u96c5\u9ed1;font-size: 14px;font-style: italic;letter-spacing: 0.544px;text-indent: 32px;widows: 1;box-sizing: border-box !important;word-wrap: break-word !important;\">\u6587\u7ae0\u4fe1\u606f\u6e90\u4e8e\u516c<\/span><span style=\"max-width: 100%;color: rgb(102, 102, 102);font-family: \u5fae\u8f6f\u96c5\u9ed1;font-size: 14px;font-style: italic;letter-spacing: 0.544px;text-indent: 32px;widows: 1;box-sizing: border-box !important;word-wrap: break-word !important;\">\u4f17\u53f7\u827e\u7f8e\u8fbe\u884c\u4e1a\u7814\u7a76<\/span><span style=\"max-width: 100%;color: rgb(102, 102, 102);font-family: \u5fae\u8f6f\u96c5\u9ed1;font-size: 14px;font-style: italic;letter-spacing: 0.544px;text-indent: 32px;widows: 1;box-sizing: border-box !important;word-wrap: break-word !important;\">&nbsp;\uff0c<\/span><span style=\"max-width: 100%;color: rgb(102, 102, 102);font-family: \u5fae\u8f6f\u96c5\u9ed1;font-size: 14px;font-style: 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rgb(35, 21, 10);box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;color: rgb(136, 136, 136);box-sizing: border-box !important;word-wrap: break-word !important;\">\u533b\u836f\u5927\u6570\u636e|\u884c\u4e1a\u52a8\u6001|\u653f\u7b56\u89e3\u8bfb<\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;word-wrap: break-word !important;\"><br  \/><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<blockquote class='keep-source'>\n<p>\u59cb\u53d1\u4e8e\u5fae\u4fe1\u516c\u4f17\u53f7\uff1a                         \u884c\u821fDrug                      <\/p>\n<\/blockquote>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>\u70b9\u51fb\u4e0a\u65b9\u7684&nbsp;\u884c\u821fDrug&nbsp;\u25b2&nbsp;\u6dfb\u52a0\u5173\u6ce8 2018\u5e74\u4e0a\u534a\u5e74\uff0cFDA\u836f\u54c1\u5ba1\u8bc4\u4e0e\u7814\u7a76\u4e2d [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":4584,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[2],"tags":[],"_links":{"self":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/4583"}],"collection":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/comments?post=4583"}],"version-history":[{"count":1,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/4583\/revisions"}],"predecessor-version":[{"id":4588,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/4583\/revisions\/4588"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/media\/4584"}],"wp:attachment":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/media?parent=4583"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/categories?post=4583"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/tags?post=4583"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}