{"id":46489,"date":"2018-09-19T01:00:00","date_gmt":"2018-09-26T01:29:05","guid":{"rendered":"http:\/\/www.05921.net\/index.php\/2018\/09\/26\/%e4%bb%b7%e6%a0%bc%e5%ae%9a%e4%ba%86%ef%bc%81keytruda%e8%b5%a0%e8%8d%af%e6%82%a3%e8%80%85%e4%b8%80%e5%b9%b4%e4%bb%85%e9%9c%8016%e4%b8%87%ef%bc%8c%e5%85%a8%e7%90%83%e6%9c%80%e4%bd%8e\/"},"modified":"2018-09-26T09:29:06","modified_gmt":"2018-09-26T01:29:06","slug":"%e4%bb%b7%e6%a0%bc%e5%ae%9a%e4%ba%86%ef%bc%81keytruda%e8%b5%a0%e8%8d%af%e6%82%a3%e8%80%85%e4%b8%80%e5%b9%b4%e4%bb%85%e9%9c%8016%e4%b8%87%ef%bc%8c%e5%85%a8%e7%90%83%e6%9c%80%e4%bd%8e","status":"publish","type":"post","link":"https:\/\/www.05921.net\/index.php\/46489\/","title":{"rendered":"\u4ef7\u683c\u5b9a\u4e86\uff01Keytruda\u8d60\u836f\u60a3\u8005\u4e00\u5e74\u4ec5\u970016\u4e07\uff0c\u5168\u7403\u6700\u4f4e"},"content":{"rendered":"<div class=\"bpp-post-content\">\n<p style=\"text-align: center;\"><img class=\"__bg_gif\"         width=\"auto\" style=\"text-align: center;white-space: normal;color: rgb(62, 62, 62);font-family: \u5fae\u8f6f\u96c5\u9ed1;z-index: -1;cursor: pointer;font-size: 14px;line-height: 22.4px;background-color: rgb(255, 255, 255);width: 558px;box-sizing: border-box !important;word-wrap: break-word !important;visibility: visible !important;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/09\/5-1537925346.jpeg\" alt=\"\u4ef7\u683c\u5b9a\u4e86\uff01Keytruda\u8d60\u836f\u60a3\u8005\u4e00\u5e74\u4ec5\u970016\u4e07\uff0c\u5168\u7403\u6700\u4f4e\" title=\"\u4ef7\u683c\u5b9a\u4e86\uff01Keytruda\u8d60\u836f\u60a3\u8005\u4e00\u5e74\u4ec5\u970016\u4e07\uff0c\u5168\u7403\u6700\u4f4e\"  \/><\/p>\n<p style=\"text-align: center;\"><br  \/><\/p>\n<p>\u3000\u30009\u670819\u65e5\uff0c\u7531\u4e2d\u56fd\u521d\u7ea7\u536b\u751f\u4fdd\u5065\u57fa\u91d1\u4f1a\u53d1\u8d77\uff0c\u9ed8\u6c99\u4e1c\uff08\u4e2d\u56fd\uff09\u6709\u9650\u516c\u53f8\u652f\u6301\u7684\u751f\u547d\u4e4b\u94a5\u2014\u2014\u80bf\u7624\u514d\u75ab\u6cbb\u7597\u60a3\u8005\u63f4\u52a9\u9879\u76ee\uff08PAP\u8ba1\u5212\uff09\u5728\u5168\u56fd\u542f\u52a8\uff0c\u65e8\u5728\u4e3a\u4e2d\u56fd\u4f4e\u4fdd\u548c\u4f4e\u6536\u5165\u5bb6\u5ead\u4e2d\u7684\u665a\u671f\u9ed1\u8272\u7d20\u7624\u60a3\u8005\u63d0\u4f9b\u836f\u54c1\u63f4\u52a9\u3002<\/p>\n<p>\u3000\u3000<\/p>\n<p>\u3000\u3000\u8bb0\u8005\u5f97\u5230\u6700\u65b0\u6d88\u606f\uff0cKeytruda\uff08\u53ef\u745e\u8fbe\uff09\u4e2d\u56fd\u96f6\u552e\u4ef7\u4e3a17918\u5143\/100mg\uff0c\u5168\u5e74\u6cbb\u7597\u8d39\u7528\u4e3a304606\u5143\uff0c\u4ec5\u4e3a\u7f8e\u56fd\u5e02\u573a\u4ef7\u683c\u768454%\uff1b\u5bf9\u4e8e\u4f4e\u6536\u5165\u60a3\u8005\uff0c\u901a\u8fc7PAP\u8ba1\u5212\u8d60\u836f\u653f\u7b56\u4e3a3+3\uff08\u4e703\u4e2a\u7597\u7a0b\u90013\u4e2a\u7597\u7a0b\uff09\uff0c\u60a3\u8005\u9700\u8d1f\u62c5\u7684\u5e74\u6cbb\u7597\u8d39\u7528\u6700\u4f4e\u4e3a161262\u5143\uff1b\u800c\u5bf9\u4e8e\u4f4e\u4fdd\u60a3\u8005\uff0c\u53ef\u4ee5\u514d\u8d39\u4f7f\u752824\u4e2a\u6708\u3002<\/p>\n<p>\u3000\u3000<\/p>\n<p>\u3000\u3000\u4e1a\u5185\u4eba\u58eb\u8ba4\u4e3a\uff0c\u8fd9\u4e00\u65b9\u9762\u5151\u73b0\u4e86\u6b64\u524d\u9ed8\u6c99\u4e1c\u6709\u5173\u5bf9\u4e2d\u665a\u671f\u9ed1\u8272\u7d20\u7624\u60a3\u8005\u63f4\u52a9\u7684\u627f\u8bfa\uff0c\u53e6\u4e00\u65b9\u9762\u4e5f\u9884\u793a\u7740\u9ed8\u6c99\u4e1cPD-1\u6291\u5236\u5242Keytruda\u5c06\u987a\u5e94\u4e2d\u56fd\u6297\u80bf\u7624\u836f\u7269\u964d\u4ef7\u7684\u5927\u52bf\u3002<\/p>\n<p>\u3000\u3000<\/p>\n<p>\u3000\u3000\u5bf9\u6b64\uff0c\u9ed8\u6c99\u4e1c\u4e2d\u56fd\u603b\u88c1\u7f57\u4e07\u91cc\uff08Joseph Romanelli\uff09\u8868\u793a\uff1a\u201c\u9ed8\u6c99\u4e1c\u975e\u5e38\u652f\u6301\u4e2d\u56fd\u653f\u5e9c\u8fd1\u5e74\u6765\u9488\u5bf9\u6297\u80bf\u7624\u836f\u7269\u7684\u4e00\u7cfb\u5217\u964d\u4ef7\u63aa\u65bd\uff0c\u5305\u62ec\u6297\u80bf\u7624\u836f\u7269\u8fdb\u53e3\u96f6\u5173\u7a0e\u4ee5\u53ca\u533b\u4fdd\u7279\u836f\u8c08\u5224\u7b49\uff0c\u9ed8\u6c99\u4e1c\u4e5f\u5e0c\u671b\u5c06\u5168\u7403\u66f4\u5148\u8fdb\u7684\u80bf\u7624\u836f\u7269\u5f15\u8fdb\u4e2d\u56fd\uff0c\u63a8\u8fdb\u4e2d\u56fd\u80bf\u7624\u836f\u7269\u7684\u53ef\u53ca\u548c\u53ef\u652f\u4ed8\u3002\u201d<\/p>\n<p>\u3000\u3000\u3000\u3000<\/p>\n<section class=\"_135editor\"     style=\"font-size: 16px;border-width: 0px;border-style: none;border-color: initial;box-sizing: border-box;\">\n<section class=\"135brush\" style=\"border-left: 5px solid #ef7060;font-weight: bold;line-height: 32px;color: #666666;padding: 5px 10px;margin-top: 10px;margin-bottom: 10px;box-sizing: border-box;\">\n<p style=\"white-space: normal;line-height: 1.5em;\"><strong style=\"caret-color: red;\"><span style=\"color: #ef7060;font-size: 18px;\">\u7b26\u5408\u8d60\u836f\u6761\u4ef6\u60a3\u8005\u5168\u7403\u82b1\u8d39\u6700\u4f4e<\/span><\/strong><\/p>\n<\/section>\n<\/section>\n<p>\u3000\u3000<br  \/><\/p>\n<p>\u3000\u3000\u636e\u6b64\u8bb0\u8005\u8ba1\u7b97\u4e86\u4e00\u7b14\u8d26\uff0c\u7b26\u5408\u8d60\u836f\u6761\u4ef6\u7684\u60a3\u8005\uff0c\u9700\u8d1f\u62c5\u7684\u5e74\u6cbb\u7597\u8d39\u7528\u6700\u4f4e\u4e3a161262\u5143\uff0c\u5b9e\u9645\u82b1\u8d39\u4ec5\u4e3a\u7f8e\u56fd\u768427%\uff0c\u582a\u79f0\u5168\u7403\u6700\u4f4e\u3002<\/p>\n<p>\u3000\u3000<\/p>\n<p>\u3000\u3000\u540c\u65f6\uff0c3+3\u4e5f\u5f00\u542f\u4e86\u56fd\u5185\u514d\u75ab\u6cbb\u7597\u836f\u7269\u6148\u5584\u8d60\u836f\u7684\u5148\u6cb3\uff0c\u4e3a\u5176\u5b83\u5df2\u7ecf\u4e0a\u5e02\u548c\u5373\u5c06\u4e0a\u5e02\u7684PD-1\/PD-L1\u6297\u4f53\u836f\u7269\u505a\u597d\u699c\u6837\u3002<\/p>\n<p>\u3000\u3000<\/p>\n<p>\u3000\u3000\u516c\u5f00\u8d44\u6599\u663e\u793a\uff0c\u4eca\u5e742\u670811\u65e5\uff0c\u9ed8\u6c99\u4e1cPD-1\u5355\u6297Keytruda\u7684\u4e0a\u5e02\u7533\u8bf7\u83b7\u5f97CDE\u627f\u529e\u53d7\u7406\uff1b7\u670826\u65e5\uff0c Keytruda\u7684\u4e0a\u5e02\u7533\u8bf7\u6b63\u5f0f\u83b7\u6279\u3002\u7528\u4e8e\u6cbb\u7597\u7ecf\u4e00\u7ebf\u6cbb\u7597\u5931\u8d25\u7684\u4e0d\u53ef\u5207\u9664\u6216\u8f6c\u79fb\u6027\u9ed1\u8272\u7d20\u7624\u7684\u6cbb\u7597\u3002\u4ece\u9012\u4ea4\u4e0a\u5e02\u7533\u8bf7\u5230\u83b7\u6279\u4ec5\u7528\u65f6163\u5929\uff0c\u521b\u4e0b\u4e86\u4e2d\u56fd\u8fdb\u53e3\u6297\u80bf\u7624\u751f\u7269\u5236\u5242\u6700\u5feb\u5ba1\u6279\u8bb0\u5f55\u3002<\/p>\n<p>\u3000\u3000<\/p>\n<p>\u3000\u3000\u76ee\u524d\uff0c\u8be5\u836f\u6b63\u7533\u8bf7\u7528\u4e8e\u665a\u671f\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u4e00\u7ebf\u6cbb\u7597\uff0c\u4e5f\u5c31\u662f\u665a\u671f\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u786e\u8bca\u540e\u9996\u6b21\u4f7f\u7528\u7684\u836f\u7269\u3002<\/p>\n<p>\u3000\u3000<\/p>\n<p>\u3000\u3000\u60a3\u8005\u63f4\u52a9\u8ba1\u5212\u4f7f\u5f97\u60a3\u8005\u53ef\u4ee5\u83b7\u5f97\u89c4\u8303\u5316\u6cbb\u7597\uff0c\u6539\u5584\u6cbb\u7597\u836f\u7269\u53ef\u53ca\u6027\uff0c\u51cf\u8f7b\u75be\u75c5\u5bf9\u60a3\u8005\u5bb6\u5ead\u548c\u793e\u4f1a\u7684\u7ecf\u6d4e\u8d1f\u62c5\u3002\u636e\u6089\uff0c\u9879\u76ee\u542f\u52a8\u540e\uff0c\u5c06\u5728\u5168\u56fd\u8d85\u8fc770\u4e2a\u57ce\u5e02\u5c55\u5f00\u3002<\/p>\n<p>\u3000\u3000<\/p>\n<p>\u3000\u3000\u636e\u4e86\u89e3\uff0c\u9ed1\u8272\u7d20\u7624\u662f\u4e00\u79cd\u6765\u6e90\u4e8e\u9ed1\u8272\u7d20\u7ec6\u80de\u7684\u6076\u6027\u80bf\u7624\uff0c\u662f\u76ae\u80a4\u764c\u4e2d\u6076\u6027\u7a0b\u5ea6\u6700\u9ad8\u7684\u764c\u79cd\uff0c\u4e5f\u662f\u4e2d\u56fd\u53d1\u75c5\u7387\u589e\u957f\u6700\u5feb\u7684\u6076\u6027\u80bf\u7624\u4e4b\u4e00\uff0c\u5e74\u589e\u957f\u7387\u4e3a3\uff05\uff5e5\uff05\uff0c\u5df2\u6210\u4e3a\u4e25\u91cd\u5371\u53ca\u4e2d\u56fd\u5c45\u6c11\u5065\u5eb7\u7684\u91cd\u8981\u75be\u75c5\u3002\u9ed1\u8272\u7d20\u7624\u6076\u5316\u7a0b\u5ea6\u8f83\u5feb\uff0c\u6781\u6613\u51fa\u73b0\u8fdc\u5904\u8f6c\u79fb\u3002<\/p>\n<p>\u3000\u3000<\/p>\n<p>\u3000\u3000\u4e2d\u56fd\u4e34\u5e8a\u80bf\u7624\u5b66\u4f1a\uff08CSCO\uff09\u6076\u6027\u9ed1\u8272\u7d20\u7624\u4e13\u5bb6\u59d4\u5458\u4f1a\u4e3b\u4efb\u59d4\u5458\u3001\u5317\u4eac\u5927\u5b66\u80bf\u7624\u533b\u9662\u526f\u9662\u957f\u90ed\u519b\u6559\u6388\u544a\u8bc9\u8bb0\u8005\uff1a\u201c\u8fc7\u53bb\u51e0\u5341\u5e74\u91cc\uff0c\u4f20\u7edf\u610f\u4e49\u4e0a\u7684\u6cbb\u7597\u65b9\u5f0f\u6709\u6548\u7387\u53ea\u67094.6%\u3002\u5982\u4eca\uff0c\u514d\u75ab\u6cbb\u7597\u4ece\u6839\u672c\u4e0a\u6539\u53d8\u4e86\u9ed1\u8272\u7d20\u7624\u8fc7\u53bb\u7684\u6cbb\u7597\u7a98\u5883\uff0c\u4e2d\u56fd\u7684\u665a\u671f\u9ed1\u8272\u7d20\u7624\u60a3\u8005\u7ec8\u4e8e\u6709\u4e86\u4e0e\u4e16\u754c\u63a5\u8f68\u7684\u6cbb\u7597\u65b9\u6848\u3002\u201d<\/p>\n<p>\u3000\u3000<\/p>\n<p>\u3000\u30002016\u5e74\u4f7f\u7528Keytruda\u6cbb\u7597655\u4f4d\u665a\u671f\u9ed1\u8272\u7d20\u7624\u60a3\u8005\u7684\u7814\u7a76\u663e\u793a\uff0c\u60a3\u8005\u6574\u4f53\u4e2d\u4f4d\u751f\u5b58\u4e3a23\u4e2a\u6708\uff0c2\u5e74\u751f\u5b58\u7387\u8fbe49%\uff0c\u67091\/3\u7684\u4eba\u80bf\u7624\u5b9e\u73b0\u7f29\u5c0f\u3002<\/p>\n<p>\u3000\u3000\u3000\u3000<\/p>\n<section class=\"_135editor\"     style=\"font-size: 16px;border-width: 0px;border-style: none;border-color: initial;box-sizing: border-box;\">\n<section class=\"135brush\" style=\"border-left: 5px solid #ef7060;font-weight: bold;line-height: 32px;color: #666666;padding: 5px 10px;margin-top: 10px;margin-bottom: 10px;box-sizing: border-box;\">\n<p style=\"white-space: normal;line-height: 1.5em;\"><strong style=\"caret-color: red;\"><span style=\"color: #ef7060;font-size: 18px;\">\u63a2\u7d22\u591a\u5143\u652f\u4ed8\u4f53\u7cfb\u964d\u4f4e\u60a3\u8005\u8d1f\u62c5<\/span><\/strong><\/p>\n<\/section>\n<\/section>\n<p>\u3000\u3000<br  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style=\"text-align: left;\"><br  \/><\/p>\n<p style=\"font-size: 16px;white-space: normal;line-height: 25.6px;max-width: 100%;min-height: 1em;color: rgb(62, 62, 62);background-color: rgb(255, 255, 255);box-sizing: border-box !important;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;line-height: 25.6px;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;color: rgb(79, 129, 189);box-sizing: border-box !important;word-wrap: break-word !important;\">\u25a0<span style=\"font-family: \u5b8b\u4f53;\">\u7f16\u8f91 \u9648\u96ea\u8587<\/span><\/span><\/strong><\/p>\n<section    style=\"font-size: 16px;white-space: normal;line-height: 25.6px;max-width: 100%;box-sizing: border-box;color: rgb(62, 62, 62);border-width: 0px;border-style: none;border-color: initial;background-color: rgb(255, 255, 255);word-wrap: break-word !important;\">\n<section  style=\"max-width: 100%;box-sizing: border-box;display: inline-block;width: 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border-box !important;word-wrap: break-word !important;\">\u56de\u590d\u201cTOP\u201d\u8f7b\u677e\u83b7\u53d6\u4e0a\u5468\u6700\u70ed\u95e8\u6587\u7ae0\uff01<\/span><span style=\"max-width: 100%;color: inherit;line-height: 1.75em;text-decoration: inherit;box-sizing: border-box !important;word-wrap: break-word !important;\">\uff0c<\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<p style=\"white-space: normal;\"><br  \/><\/p>\n<p style=\"margin-bottom: 10px;font-size: 16px;white-space: normal;line-height: 25.6px;max-width: 100%;min-height: 1em;color: rgb(62, 62, 62);background-color: rgb(255, 255, 255);box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;color: rgb(192, 0, 0);box-sizing: border-box !important;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-family: \u5b8b\u4f53;box-sizing: border-box 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