{"id":46695,"date":"2018-09-25T01:00:00","date_gmt":"2018-09-26T01:31:15","guid":{"rendered":"http:\/\/www.05921.net\/index.php\/2018\/09\/26\/2017%e5%b9%b4%e5%ba%a6%e7%94%9f%e7%89%a9%e6%8a%80%e6%9c%af%e9%a2%86%e5%9f%9f20%e4%bd%8d%e9%a1%b6%e5%b0%96%e8%bd%ac%e5%8c%96%e7%a0%94%e7%a9%b6%e4%ba%ba%e5%91%98\/"},"modified":"2018-09-26T09:31:16","modified_gmt":"2018-09-26T01:31:16","slug":"2017%e5%b9%b4%e5%ba%a6%e7%94%9f%e7%89%a9%e6%8a%80%e6%9c%af%e9%a2%86%e5%9f%9f20%e4%bd%8d%e9%a1%b6%e5%b0%96%e8%bd%ac%e5%8c%96%e7%a0%94%e7%a9%b6%e4%ba%ba%e5%91%98","status":"publish","type":"post","link":"https:\/\/www.05921.net\/index.php\/46695\/","title":{"rendered":"2017\u5e74\u5ea6\u751f\u7269\u6280\u672f\u9886\u57df20\u4f4d\u201c\u9876\u5c16\u8f6c\u5316\u7814\u7a76\u4eba\u5458\u201d"},"content":{"rendered":"<div class=\"bpp-post-content\">\n<p style=\"padding-top: 0.5em;padding-bottom: 0.5em;white-space: normal;border-width: initial;border-style: none;border-color: initial;color: rgb(102, 102, 102);font-family: &quot;Microsoft YaHei&quot;, arial, tahoma, Helevtica, Verdana, sans-serif;font-size: 14px;text-align: justify;text-indent: 2em;line-height: 1.75em;\">\u57fa\u4e8e2017\u5e74\u6388\u4e88\u7684\u603b\u4e13\u5229\uff08\u7f8e\u56fd\u548c\u6b27\u6d32\uff09\u548c\u8fc7\u53bb5\u5e74\u4e13\u5229\u5f15\u7528\u6b21\u6570\u548cH\u6307\u6570\uff08H-index\uff0c\u4e00\u79cd\u786e\u5b9a\u79d1\u5b66\u5bb6\u7684\u5df2\u53d1\u8868\u4f5c\u54c1\u7684\u5f71\u54cd\u529b\u7684\u65b9\u6cd5\uff0c\u8d8a\u9ad8\u610f\u5473\u7740\u5f71\u54cd\u529b\u8d8a\u5927\uff09\uff0c\u6211\u4eec\u5bf9\u751f\u7269\u6280\u672f\u9886\u57df\u9876\u7ea7\u8f6c\u5316\u7814\u7a76\u4eba\u5458\u8fdb\u884c\u4e86\u6392\u540d\uff08\u88681\uff09\u3002 \u9ebb\u7701\u7406\u5de5\u5b66\u9662\uff08Massachusetts Institute of Technology\uff09\u7684Robert Langer\u518d\u6b21\u4f4d\u5c45\u699c\u9996\uff1b\u5bbe\u5915\u6cd5\u5c3c\u4e9a\u5927\u5b66\uff08University of Pennsylvania\uff09\u7684James Wilson\u4ece2016\u5e74\u7684\u7b2c10\u540d\u6500\u5347\u81f3\u7b2c2\u540d\uff1b\u5fb7\u5dde\u5927\u5b66\u897f\u5357\u533b\u5b66\u4e2d\u5fc3\uff08University of Texas Southwestern Medical Center\uff09\u7684Joseph Ready\u4e5f\u6740\u5165\u699c\u5355\uff1b\u4e1c\u4eac\u5927\u5b66\uff08University of Tokyo\uff09\u7684\u4e09\u4f4d\u7814\u7a76\u4eba\u5458\u4e5f\u699c\u4e0a\u6709\u540d\u3002\u9ebb\u7701\u7406\u5de5\u5b66\u9662\uff08Massachusetts Institute of Technology\uff09\u7684\u5f20\u950b\u62e5\u6709\u5f15\u7528\u6b21\u6570\u6700\u591a\u7684\u4e13\u5229\uff08\u88682\uff09\u3002\u4ece\u88ab\u5f15\u7528\u6b21\u6570\u6700\u591a\u7684\u4e13\u5229\u6765\u770b\uff0cCRISPR\u6700\u53d7\u5173\u6ce8\uff0c\u8fd9\u4e3b\u8981\u5f52\u529f\u4e8e\u6838\u9178\u7597\u6cd5\u7684\u65e5\u76ca\u706b\u7206\u3002<\/p>\n<p style=\"padding-top: 0.5em;padding-bottom: 0.5em;white-space: normal;border-width: initial;border-style: none;border-color: initial;color: rgb(102, 102, 102);font-family: &quot;Microsoft YaHei&quot;, arial, tahoma, Helevtica, Verdana, sans-serif;font-size: 14px;\"><br  \/><\/p>\n<table align=\"center\" cellpadding=\"1\" cellspacing=\"1\">\n<caption><strong>\u88681. 2017\u5e74\u5ea6\u751f\u7269\u6280\u672f\u9886\u57df20\u4f4d\u201c\u9876\u5c16\u8f6c\u5316\u7814\u7a76\u4eba\u5458\u201d<\/strong><br  \/><\/caption>\n<tbody>\n<tr>\n<td width=\"94.66666666666667\"><strong>\u4e13\u5229\u53d1\u660e\u4eba\/\u53d7\u8ba9\u4eba<\/strong><\/td>\n<td width=\"89.66666666666667\"><strong>\u6388\u4e88\u7684\u4e13\u5229\u6570\uff082017\uff09<\/strong><\/td>\n<td width=\"189.66666666666666\"><strong>2013-2017\u5e74\u95f4\u88ab\u5f15\u7528\u6b21\u6570\u6700\u591a\u7684\u4e13\u5229\uff08\u5f15\u7528\u6b21\u6570\uff09<\/strong><\/td>\n<td width=\"78\"><strong>H-index\uff0c\u622a\u6b622018\/7\/31<\/strong><\/td>\n<\/tr>\n<tr>\n<td width=\"94.66666666666667\">Langer, Robert S.\/\u9ebb\u7701\u7406\u5de5\u5b66\u9662<\/td>\n<td width=\"89.66666666666667\">18<\/td>\n<td width=\"190.66666666666666\">US 8450298\uff1b\u6c28\u57fa\u9187\u7c7b\u8102\u8d28\u53ca\u5176\u7528\u9014\uff08Aminoalcohol lipidoids and uses thereof\uff09\uff0834\uff09<\/td>\n<td width=\"78\">260<\/td>\n<\/tr>\n<tr>\n<td width=\"94.66666666666667\">Wilson, James M.\/\u5bbe\u5915\u6cd5\u5c3c\u4e9a\u5927\u5b66<\/td>\n<td width=\"89.66666666666667\">17<\/td>\n<td width=\"191.66666666666666\">US 8524446\uff1b\u817a\u76f8\u5173\u75c5\u6bd2\u68c0\u6d4b\u65b9\u6cd5\uff08Method for detecting adeno-associated virus\uff09\uff089\uff09<\/td>\n<td width=\"78\">113<\/td>\n<\/tr>\n<tr>\n<td width=\"94.66666666666667\">Vogelstein, Bert\uff1bKinzler, Kenneth W.\/\u7ea6\u7ff0\u970d\u666e\u91d1\u65af\u5927\u5b66&amp;\u675c\u514b\u5927\u5b66<\/td>\n<td width=\"89.66666666666667\">16,16<\/td>\n<td width=\"193.66666666666666\">US 8685660\uff1b\u6076\u6027\u80f6\u8d28\u7624\u4e2d\u5f02\u67e0\u6aac\u9178\u8131\u6c22\u9176\u548c\u5176\u5b83\u57fa\u56e0\u7684\u9057\u4f20\u6539\u53d8\uff08Genetic alterations in isocitrate dehydrogenase and other genes in malignant glioma\uff09\uff082\uff09<\/td>\n<td width=\"78\">250, 213<\/td>\n<\/tr>\n<tr>\n<td width=\"94.66666666666667\">\u9ad8\u5149\u576a\/\u9a6c\u8428\u8bf8\u585e\u5927\u5b66&amp;\u5bbe\u5915\u6cd5\u5c3c\u4e9a\u5927\u5b66<\/td>\n<td width=\"89.66666666666667\">13<\/td>\n<td width=\"195.66666666666666\">US 8734809\uff1bAAV\u53ca\u5176\u7528\u9014\uff08AAV&#8217;s and uses thereof\uff09\uff0813\uff09<\/td>\n<td width=\"78\">70<\/td>\n<\/tr>\n<tr>\n<td width=\"94.66666666666667\">\u5362\u715c\u660e\/\u9999\u6e2f\u4e2d\u6587\u5927\u5b66&amp;Sequenom\u516c\u53f8<\/td>\n<td width=\"89.66666666666667\">12<\/td>\n<td width=\"197.66666666666666\">US 8467976\uff1b\u6bcd\u4f53\u751f\u7269\u6837\u54c1\u7684\u80ce\u513f\u57fa\u56e0\u7ec4\u5206\u6790\uff08Fetal genomic analysis from a maternal biological sample\uff09\uff0818\uff09<\/td>\n<td width=\"78\">82<\/td>\n<\/tr>\n<tr>\n<td width=\"94.66666666666667\">\u5f20\u950b\/\u535a\u5fb7\u7814\u7a76\u6240\uff08Broad Institute\uff09&amp;\u9ebb\u7701\u7406\u5de5\u5b66\u9662<\/td>\n<td width=\"89.66666666666667\">11<\/td>\n<td width=\"198.66666666666666\">US 8697359\uff1b\u7528\u4e8e\u6539\u53d8\u57fa\u56e0\u4ea7\u7269\u8868\u8fbe\u7684CRISPR-Cas\u7cfb\u7edf\u548c\u65b9\u6cd5\uff08CRISPR-Cas systems and methods for altering expression of gene products\uff09\uff08168\uff09<\/td>\n<td width=\"78\">77<\/td>\n<\/tr>\n<tr>\n<td width=\"94.66666666666667\">Weissman, Irving L.\/\u65af\u5766\u798f\u5927\u5b66<\/td>\n<td width=\"89.66666666666667\">11<\/td>\n<td width=\"199.66666666666666\">US 8562997\uff1b\u901a\u8fc7\u963b\u65adCD47\u6cbb\u7597\u6025\u6027\u9ad3\u6837\u767d\u8840\u75c5\u7684\u65b9\u6cd5\uff08Methods of treating acute myeloid leukemia by blocking CD47\uff09\uff0817\uff09<\/td>\n<td width=\"78\">158<\/td>\n<\/tr>\n<tr>\n<td width=\"94.66666666666667\">Yamanaka, Shinya\/\u4e1c\u4eac\u5927\u5b66<\/td>\n<td width=\"89.66666666666667\">11<\/td>\n<td width=\"200.66666666666666\">US 8530238\uff1b\u6709\u6548\u6784\u5efaiPS\u7ec6\u80de\u7684\u65b9\u6cd5\uff08Method of efficiently establishing induced pluripotent stem cells\uff09\uff088\uff09<\/td>\n<td width=\"78\">87<\/td>\n<\/tr>\n<tr>\n<td width=\"94.66666666666667\">Weiner, David.B\/\u5bbe\u5915\u6cd5\u5c3c\u4e9a\u5927\u5b66<\/td>\n<td width=\"89.66666666666667\">10<\/td>\n<td width=\"201.66666666666666\">US 8852609\uff1b\u7f16\u7801\u57fa\u5b54\u80af\u96c5\u75c5\u6bd2\u76f8\u5173\u86cb\u767d\u6216\u6838\u9178\u7684\u5171\u6709\u5e8f\u5217\uff08Consensus sequences of Chikungunya viral proteins, nucleic acid molecules encoding the same, and compositions and methods for using the same\uff09\uff083\uff09<\/td>\n<td width=\"78\">74<\/td>\n<\/tr>\n<tr>\n<td width=\"94.66666666666667\">Atala, Anthony\/\u7ef4\u514b\u68ee\u6797\u5927\u5b66\u5065\u5eb7\u79d1\u5b66\u4e2d\u5fc3\uff08Wake Forest University Health Sciences\uff09<\/td>\n<td width=\"89.66666666666667\">10<\/td>\n<td width=\"203.66666666666666\">US 8491457\uff1b\u8840\u7ba1\u7ec4\u7ec7\u5de5\u7a0b \uff08Tissue engineered blood vessels\uff09\uff083\uff09<\/td>\n<td width=\"78\">92<\/td>\n<\/tr>\n<tr>\n<td width=\"94.66666666666667\">Schultz, Peter G. \/\u65af\u514b\u5229\u666e\u65af\u7814\u7a76\u6240\uff08Scripps Research Institute\uff09\u3001\u8bfa\u534e\u516c\u53f8\u3001Cardiac Pacemakers\u516c\u53f8\u548cIRM\u6709\u9650\u8d23\u4efb\u516c\u53f8<\/td>\n<td width=\"89.66666666666667\">10<\/td>\n<td width=\"205.66666666666666\">US 9139633\uff1b\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u5206\u5316\uff08Mesenchymal stem cell differentiation\uff09\uff085\uff09<\/td>\n<td width=\"78\">126<\/td>\n<\/tr>\n<tr>\n<td width=\"94.66666666666667\">Deisseroth, Karl\/\u65af\u5766\u798f\u5927\u5b66<\/td>\n<td width=\"89.66666666666667\">10<\/td>\n<td width=\"205.66666666666666\">US 8398692\uff1b\u9776\u7ec6\u80de\u5149\u5b66\u523a\u6fc0\u7cfb\u7edf\uff08System for optical stimulation of target cells\uff09\uff0851\uff09<\/td>\n<td width=\"78\">123<\/td>\n<\/tr>\n<tr>\n<td width=\"94.66666666666667\">June, Carl H. \/\u5bbe\u5915\u6cd5\u5c3c\u4e9a\u5927\u5b66<\/td>\n<td width=\"89.66666666666667\">9<\/td>\n<td width=\"205.66666666666666\">US 8906682\uff1b\u764c\u75c7\u6cbb\u7597\u65b9\u6cd5\uff08Methods for treatment of cancer\uff09\uff0828\uff09<\/td>\n<td width=\"78\">134<\/td>\n<\/tr>\n<tr>\n<td width=\"94.66666666666667\">Lanzavecchia, Antonio\/\u8d1d\u6797\u4f50\u7eb3\u751f\u7269\u533b\u5b66\u7814\u7a76\u6240\uff08Institute for Research in Biomedicine in Bellinzona\uff09<\/td>\n<td width=\"89.66666666666667\">9<\/td>\n<td width=\"205.66666666666666\">US 8435524\uff1b\u4eba\u5de8\u7ec6\u80de\u75c5\u6bd2\u4e2d\u548c\u6297\u4f53\u53ca\u5176\u4f5c\u7528\uff08Human cytomegalovirus neutralizing antibodies and use thereof \uff09\uff0812\uff09<\/td>\n<td width=\"78\">131<\/td>\n<\/tr>\n<tr>\n<td width=\"94.66666666666667\">Farokhzad, Omid C.\/ \u5e03\u5217\u6839\u548c\u5987\u5973\u533b\u9662\uff08Brigham And Women&#8217;s Hospital\uff09 &amp; \u9ebb\u7701\u7406\u5de5\u5b66\u9662<\/td>\n<td width=\"89.66666666666667\">9<\/td>\n<td width=\"205.66666666666666\">US 8367113\uff1b\u529f\u80fd\u9897\u7c92\u805a\u5408\u7269\uff08Polymers for functional particles \uff09\uff0828\uff09<\/td>\n<td width=\"78\">82<\/td>\n<\/tr>\n<tr>\n<td width=\"94.66666666666667\">\u4e01\u80dc\/\u65af\u514b\u91cc\u666e\u65af\u7814\u7a76\u6240\uff08Scripps Research Institute\uff09<\/td>\n<td width=\"89.66666666666667\">9<\/td>\n<td width=\"205.66666666666666\">US 8906677\uff1b\u5e72\u7ec6\u80de\u751f\u6210\u548c\u7ef4\u6301\uff08Generation and maintenance of stem cells\uff09\uff0810\uff09<\/td>\n<td width=\"78\">63<\/td>\n<\/tr>\n<tr>\n<td width=\"94.66666666666667\">Papadopoulos, Nickolas\/\u7ea6\u7ff0\u970d\u666e\u91d1\u65af\u5927\u5b66\u548c\u675c\u514b\u5927\u5b66\uff08Duke University\uff09<\/td>\n<td width=\"89.66666666666667\">9<\/td>\n<td width=\"205.66666666666666\">US 8685660\uff1b\u6076\u6027\u80f6\u8d28\u7624\u4e2d\u5f02\u67e0\u6aac\u9178\u8131\u6c22\u9176\u548c\u5176\u5b83\u57fa\u56e0\u7684\u9057\u4f20\u6539\u53d8\uff08Genetic alterations in isocitrate dehydrogenase and other genes in malignant glioma \uff09\uff082\uff09<\/td>\n<td width=\"78\">50<\/td>\n<\/tr>\n<tr>\n<td width=\"94.66666666666667\">Ready, Joseph\/\u5fb7\u514b\u8428\u65af\u5927\u5b66\u7cfb\u7edf<\/td>\n<td width=\"89.66666666666667\">9<\/td>\n<td width=\"205.66666666666666\">US 8362277 &amp; US 8604074\uff1b\u4fc3\u795e\u7ecf\u65b0\u751f\u5316\u5408\u7269\uff08Pro-neurogenic compounds\uff09\uff08\u5747\u4e3a47\uff09<\/td>\n<td width=\"78\">21<\/td>\n<\/tr>\n<tr>\n<td width=\"94.66666666666667\">Bradner, James E. \/\u54c8\u4f5b\u5927\u5b66&amp;\u4e39\u5a1c\u6cd5\u4f2f\u764c\u75c7\u7814\u7a76\u9662\uff08Dana-Farber Cancer Institute\uff09<\/td>\n<td width=\"89.66666666666667\">8<\/td>\n<td width=\"205.66666666666666\">US 8383855\uff1b\u7ec4\u86cb\u767d\u53bb\u4e59\u9170\u5316\u9176\u6291\u5236\u5242\uff08Histone deacetylase inhibitors\uff09\uff0811\uff09<\/td>\n<td width=\"78\">79<\/td>\n<\/tr>\n<tr>\n<td width=\"94.66666666666667\">Tanoue, Takeshi; Honda, Kenya; Atarashi, Koji\/\u4e1c\u4eac\u5927\u5b66<\/td>\n<td width=\"89.66666666666667\">8\uff0c8\uff0c8<\/td>\n<td width=\"205.66666666666666\">US 9415079\uff1b\u8bf1\u5bfc\u8c03\u8282\u6027T\u7ec6\u80de\u589e\u6b96\u6216\u79ef\u7d2f\u7684\u6210\u5206\uff08Composition for inducing proliferation or accumulation of regulatory T cells\uff09\uff089\uff09<\/td>\n<td width=\"78\">16, 40, 24<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p style=\"padding-top: 0.5em;padding-bottom: 0.5em;white-space: normal;border-width: initial;border-style: none;border-color: initial;color: rgb(102, 102, 102);font-family: &quot;Microsoft YaHei&quot;, arial, tahoma, Helevtica, Verdana, sans-serif;font-size: 14px;\">\u53e6\u591610\u4f4d\u7814\u7a76\u8005\uff08\u4f5c\u4e3a\u53d1\u660e\u4eba\u6216\u5171\u540c\u53d1\u660e\u4eba\uff09\u5206\u522b\u62e5\u67098\u9879\u4e13\u5229\u3002H-index\u7531\u7814\u7a76\u4eba\u5458\u63d0\u4f9b\uff0c\u6216\u901a\u8fc7Web of Science\u6216Google Scholar\u8ba1\u7b97\u3002<\/p>\n<p style=\"padding-top: 0.5em;padding-bottom: 0.5em;white-space: normal;border-width: initial;border-style: none;border-color: initial;color: rgb(102, 102, 102);font-family: &quot;Microsoft YaHei&quot;, arial, tahoma, Helevtica, Verdana, sans-serif;font-size: 14px;\">&nbsp;<\/p>\n<table align=\"center\" cellpadding=\"1\" cellspacing=\"1\">\n<caption><strong>\u88682. 2013-2017\u5e74\u95f4\u5f15\u7528\u6b21\u6570\u6700\u591a\u76845\u4e2a\u4e13\u5229<\/strong><br  \/><\/caption>\n<tbody>\n<tr>\n<td width=\"222.66666666666666\"><strong>\u4e13\u5229\u53f7\uff1a\u4e13\u5229\u540d\u79f0<\/strong><\/td>\n<td width=\"49.66666666666667\" style=\"word-break: break-all;\">\n<p><strong>\u53d1<\/strong><strong>\u5e03<\/strong><\/p>\n<p><strong>\u5e74\u4efd<\/strong><\/p>\n<\/td>\n<td width=\"130.66666666666666\"><strong>\u53d1\u660e\u4eba\/\u53d7\u8ba9\u4eba<\/strong><\/td>\n<td width=\"69.66666666666669\"><strong>\u622a\u6b622018\/3\/16\u7684\u5f15\u7528\u6b21\u6570<\/strong><\/td>\n<\/tr>\n<tr>\n<td width=\"222.66666666666666\">US 8119380 B2\uff1a\u8f6c\u57fa\u56e0\u9ea6\u8349\u754f\u964d\u89e3\u5fae\u751f\u7269\u7684\u6784\u5efa\u65b9\u6cd5\u548c\u539f\u6599\uff08Methods and materials for making and using transgenic dicamba-degrading organisms\uff09<\/td>\n<td width=\"49.66666666666667\">2012<\/td>\n<td width=\"130.66666666666666\">Donald P. Weeks, Xiao-Zhuo Wang, Patricia L. Herman\/\u5185\u5e03\u62c9\u65af\u52a0\u5927\u5b66\uff08University of Nebraska\uff09<\/td>\n<td width=\"69.66666666666669\">188<\/td>\n<\/tr>\n<tr>\n<td width=\"222.66666666666666\">US 8697359 B1\uff1a\u7528\u4e8e\u6539\u53d8\u57fa\u56e0\u4ea7\u7269\u8868\u8fbe\u7684CRISPR-Cas\u7cfb\u7edf\u548c\u65b9\u6cd5\uff08CRISPR-Cas systems and methods for altering expression of gene products\uff09<\/td>\n<td width=\"49.66666666666667\">2014<\/td>\n<td width=\"130.66666666666666\">\u5f20\u950b\/\u535a\u5fb7\u7814\u7a76\u6240&amp;\u9ebb\u7701\u7406\u5de5\u5b66\u9662<\/td>\n<td width=\"69.66666666666669\">166<\/td>\n<\/tr>\n<tr>\n<td width=\"222.66666666666666\">US 8642660 B2\uff1a\u6539\u53d8\u771f\u6838\u751f\u7269\u5bff\u547d\u7684\u65b9\u6cd5\uff08Method for altering the lifespan of eukaryotic organisms\uff09<\/td>\n<td width=\"49.66666666666667\">2014<\/td>\n<td width=\"130.66666666666666\">David Scott Goldfarb\/ \u7f57\u5f7b\u65af\u7279\u5927\u5b66\uff08University of Rochester\uff09<\/td>\n<td width=\"69.66666666666669\">92<\/td>\n<\/tr>\n<tr>\n<td width=\"222.66666666666666\">US 8865406 B2\uff1a\u7528\u4e8e\u5e8f\u5217\u64cd\u63a7\u7684\u5de5\u7a0b\u5316\u548c\u4f18\u5316\u7cfb\u7edf\u3001\u65b9\u6cd5\u548c\u9176\u7ec4\u5408\u7269\uff08Engineering and optimization of improved systems, methods and enzyme compositions for sequence manipulation\uff09<\/td>\n<td width=\"49.66666666666667\">2014<\/td>\n<td width=\"130.66666666666666\">\u5f20\u950b\uff0cFei Ran\/\u535a\u5fb7\u7814\u7a76\u6240\u3001\u9ebb\u7701\u7406\u5de5\u5b66\u9662&amp;\u54c8\u4f5b\u5927\u5b66<\/td>\n<td width=\"69.66666666666669\">68<\/td>\n<\/tr>\n<tr>\n<td width=\"222.66666666666666\">US 8795965 B2\uff1a\u7528\u4e8e\u5e8f\u5217\u64cd\u7eb5\u7684CRISPR-Cas\u7cfb\u7edf\u3001\u65b9\u6cd5\u548c\u7ec4\u5408\u7269\uff08CRISPR-Cas component systems, methods and compositions for sequence manipulation\uff09<\/td>\n<td width=\"49.66666666666667\">2014<\/td>\n<td width=\"130.66666666666666\">\u5f20\u950b\/\u535a\u5fb7\u7814\u7a76\u6240&amp;\u9ebb\u7701\u7406\u5de5\u5b66\u9662<\/td>\n<td width=\"69.66666666666669\">67<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p style=\"padding-top: 0.5em;padding-bottom: 0.5em;white-space: normal;border-width: initial;border-style: none;border-color: initial;color: rgb(102, 102, 102);font-family: &quot;Microsoft YaHei&quot;, arial, tahoma, Helevtica, Verdana, sans-serif;font-size: 14px;\"><strong><br  \/><img loading=\"lazy\" class=\"aligncenter size-medium wp-image-37563\"     height=\"300\" style=\"padding: 3px;border-width: 1px;border-style: solid;border-color: rgb(225, 225, 225);z-index: 2;cursor: pointer;border-radius: 3px;clear: both;display: block;visibility: visible;text-align: center;opacity: 1;top: 0px;left: 0px;margin: 10px 124.913px;right: 0px;bottom: 0px;\" width=\"300\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/09\/6-1537925476.jpeg\" alt=\"2017\u5e74\u5ea6\u751f\u7269\u6280\u672f\u9886\u57df20\u4f4d\u201c\u9876\u5c16\u8f6c\u5316\u7814\u7a76\u4eba\u5458\u201d\" title=\"2017\u5e74\u5ea6\u751f\u7269\u6280\u672f\u9886\u57df20\u4f4d\u201c\u9876\u5c16\u8f6c\u5316\u7814\u7a76\u4eba\u5458\u201d\"  \/><span class=\"lightbox_image ie6fix\" style=\"z-index: 1;top: 4344px;left: 176px;height: 308px;width: 308px;\"><\/span><\/strong><\/p>\n<p style=\"padding-top: 0.5em;padding-bottom: 0.5em;white-space: normal;border-width: initial;border-style: none;border-color: initial;color: rgb(102, 102, 102);font-family: &quot;Microsoft YaHei&quot;, arial, tahoma, Helevtica, Verdana, sans-serif;font-size: 14px;text-align: center;\"><strong>\u56fe1 2013-2017\u95f4\u5f15\u7528\u6b21\u6570\u6700\u591a\u768450\u4e2a\u4e13\u5229\u5173\u6ce8\u9886\u57df<\/strong>&nbsp;<\/p>\n<p style=\"padding-top: 0.5em;padding-bottom: 0.5em;white-space: normal;border-width: initial;border-style: none;border-color: initial;color: rgb(102, 102, 102);font-family: &quot;Microsoft YaHei&quot;, arial, tahoma, Helevtica, Verdana, sans-serif;font-size: 14px;\"><strong>\u539f\u6587\u68c0\u7d22\uff1a<\/strong><br  \/>Brady Huggett &amp; Kathryn Paisner. (2018) Top 20 translational researchers of 2017.&nbsp;<em>Nature Biotechnology<\/em>, 36:798.&nbsp;<br  \/><\/p>\n<p style=\"font-size: 16px;white-space: normal;max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);letter-spacing: 0.544px;background-color: rgb(255, 255, 255);font-family: Helvetica, Arial, sans-serif;text-align: center;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><strong style=\"max-width: 100%;font-size: 20px;font-family: -apple-system-font, BlinkMacSystemFont, Arial, sans-serif;letter-spacing: 0.544px;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;color: rgb(255, 0, 0);box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u8bc6\u522b\u5fae\u4fe1\u4e8c\u7ef4\u7801\uff0c\u6dfb\u52a0\u751f\u7269\u5236\u54c1\u5708\u521b\u59cb\u4eba\uff0c\u7b26\u5408\u6761\u4ef6\u8005\u5373\u53ef\u52a0\u5165\u751f\u7269\u5236\u54c1\u5708\u5fae\u4fe1\u7fa4\uff01<\/span><\/strong><br style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"  \/><\/p>\n<p style=\"font-size: 16px;white-space: normal;max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);letter-spacing: 0.544px;background-color: rgb(255, 255, 255);font-family: -apple-system-font, BlinkMacSystemFont, Arial, sans-serif;text-align: center;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 18px;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;color: rgb(0, 209, 0);box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u8bf7\u6ce8\u660e\uff1a\u59d3\u540d+\u7814\u7a76\u65b9\u5411\uff01<\/span><\/strong><\/span><\/p>\n<p style=\"font-size: 16px;white-space: normal;max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);letter-spacing: 0.544px;background-color: rgb(255, 255, 255);font-family: \u5fae\u8f6f\u96c5\u9ed1;text-align: center;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><img class=\"\"      width=\"269px\"  style=\"box-sizing: border-box !important;overflow-wrap: break-word !important;visibility: visible !important;width: 269px !important;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/09\/0-1537925476.jpeg\" alt=\"2017\u5e74\u5ea6\u751f\u7269\u6280\u672f\u9886\u57df20\u4f4d\u201c\u9876\u5c16\u8f6c\u5316\u7814\u7a76\u4eba\u5458\u201d\" title=\"2017\u5e74\u5ea6\u751f\u7269\u6280\u672f\u9886\u57df20\u4f4d\u201c\u9876\u5c16\u8f6c\u5316\u7814\u7a76\u4eba\u5458\u201d\"  \/><\/p>\n<p style=\"font-size: 16px;white-space: normal;max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);letter-spacing: 0.544px;text-align: justify;background-color: rgb(255, 255, 255);font-family: \u5fae\u8f6f\u96c5\u9ed1;line-height: 25.6px;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;line-height: 24px;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><img class=\"\"    width=\"555\"  style=\"text-indent: 0em;line-height: 25.6px;vertical-align: middle;box-sizing: border-box !important;overflow-wrap: break-word !important;visibility: visible !important;max-height: 1.2em !important;width: 640px !important;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/09\/6-1537925476.png\" alt=\"2017\u5e74\u5ea6\u751f\u7269\u6280\u672f\u9886\u57df20\u4f4d\u201c\u9876\u5c16\u8f6c\u5316\u7814\u7a76\u4eba\u5458\u201d\" title=\"2017\u5e74\u5ea6\u751f\u7269\u6280\u672f\u9886\u57df20\u4f4d\u201c\u9876\u5c16\u8f6c\u5316\u7814\u7a76\u4eba\u5458\u201d\"  \/><\/span><\/p>\n<section style=\"font-size: 16px;white-space: normal;max-width: 100%;color: rgb(51, 51, 51);letter-spacing: 0.544px;background-color: rgb(255, 255, 255);font-family: \u5fae\u8f6f\u96c5\u9ed1;text-align: center;line-height: 25.6px;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<section style=\"margin-top: 0.5em;margin-bottom: 0.5em;max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<section style=\"margin: -0.9em auto 0.9em;max-width: 100%;width: 0.6em;height: 0.6em;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<section style=\"margin-left: 1px;max-width: 100%;box-sizing: border-box;border-radius: 100%;width: 9.59px;height: 9.59px;background-color: rgb(170, 33, 94);overflow-wrap: break-word !important;\"><br  style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"  \/><\/section>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"white-space: normal;max-width: 100%;color: rgb(51, 51, 51);letter-spacing: 0.544px;background-color: rgb(255, 255, 255);font-family: \u5fae\u8f6f\u96c5\u9ed1;font-size: 14px;text-align: center;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<section style=\"margin-top: 10px;margin-bottom: 10px;padding-left: 4px;max-width: 100%;box-sizing: border-box;text-align: justify;overflow-wrap: break-word !important;\">\n<section style=\"margin-bottom: 0.2em;max-width: 100%;width: 666px;vertical-align: bottom;display: inline-block;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box;width: 657.207px;border-top: 1px solid rgb(170, 33, 94);overflow-wrap: break-word !important;\"><\/section>\n<section style=\"margin-top: -4px;margin-right: -4px;max-width: 100%;box-sizing: border-box;border-radius: 100%;width: 8.76953px;height: 8px;background-color: rgb(170, 33, 94);overflow-wrap: break-word !important;\"><\/section>\n<\/section>\n<section style=\"margin-top: -1.5em;max-width: 100%;text-align: right;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box;border-radius: 100%;width: 2em;height: 2em;text-align: center;color: rgb(255, 255, 255);line-height: 2em;vertical-align: top;display: inline-block;background-color: rgb(170, 33, 94);overflow-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;color: rgb(170, 33, 94);box-sizing: border-box !important;overflow-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 18px;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><\/span><\/strong><\/span>\u7248<\/section>\n<\/section>\n<section style=\"max-width: 100%;box-sizing: border-box;border-radius: 100%;width: 2em;height: 2em;text-align: center;color: rgb(255, 255, 255);line-height: 2em;vertical-align: top;display: inline-block;background-color: rgb(170, 33, 94);overflow-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u6743<\/section>\n<\/section>\n<section style=\"max-width: 100%;box-sizing: border-box;border-radius: 100%;width: 2em;height: 2em;text-align: center;color: rgb(255, 255, 255);line-height: 2em;vertical-align: top;display: inline-block;background-color: rgb(170, 33, 94);overflow-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u58f0<\/section>\n<\/section>\n<section style=\"max-width: 100%;box-sizing: border-box;border-radius: 100%;width: 2em;height: 2em;text-align: center;color: rgb(255, 255, 255);line-height: 2em;vertical-align: top;display: inline-block;background-color: rgb(170, 33, 94);overflow-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u660e<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<p style=\"white-space: normal;max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);font-family: -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;font-size: 17px;letter-spacing: 0.544px;text-align: justify;background-color: rgb(255, 255, 255);box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;color: rgb(105, 115, 117);font-family: \u5fae\u8f6f\u96c5\u9ed1;font-size: 14px;letter-spacing: 1px;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u672c\u516c\u4f17\u53f7\u6240\u6709\u8f6c\u8f7d\u6587\u7ae0\u7cfb\u51fa\u4e8e\u4f20\u9012\u66f4\u591a\u4fe1\u606f\u4e4b\u76ee\u7684\uff0c\u4e14\u660e\u786e\u6ce8\u660e\u6765\u6e90\u548c\u4f5c\u8005\uff0c\u4e0d\u5e0c\u671b\u88ab\u8f6c\u8f7d\u7684\u5a92\u4f53\u6216\u4e2a\u4eba\u53ef\u4e0e\u6211\u4eec\u8054\u7cfb(cbplib@163.com)\uff0c\u6211\u4eec\u5c06\u7acb\u5373\u8fdb\u884c\u5220\u9664\u5904\u7406\u3002\u6240\u6709\u6587\u7ae0\u4ec5\u4ee3\u8868\u4f5c\u8005\u89c2\u70b9\uff0c\u4e0d\u4ee3\u8868\u672c\u7ad9\u7acb\u573a\u3002<\/span><br style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"  \/><\/p>\n<p style=\"font-size: 16px;white-space: normal;max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);letter-spacing: 0.544px;text-align: justify;background-color: rgb(255, 255, 255);font-family: \u5fae\u8f6f\u96c5\u9ed1;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<\/p><\/div>\n","protected":false},"excerpt":{"rendered":"<p>\u57fa\u4e8e2017\u5e74\u6388\u4e88\u7684\u603b\u4e13\u5229\uff08\u7f8e\u56fd\u548c\u6b27\u6d32\uff09\u548c\u8fc7\u53bb5\u5e74\u4e13\u5229\u5f15\u7528\u6b21\u6570\u548cH\u6307\u6570\uff08H-index\uff0c\u4e00\u79cd\u786e\u5b9a\u79d1\u5b66\u5bb6\u7684\u5df2\u53d1\u8868 [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":46696,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[2],"tags":[],"_links":{"self":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/46695"}],"collection":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/comments?post=46695"}],"version-history":[{"count":1,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/46695\/revisions"}],"predecessor-version":[{"id":46700,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/46695\/revisions\/46700"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/media\/46696"}],"wp:attachment":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/media?parent=46695"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/categories?post=46695"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/tags?post=46695"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}