{"id":48619,"date":"2018-09-22T01:00:00","date_gmt":"2018-09-26T01:50:59","guid":{"rendered":"http:\/\/www.05921.net\/index.php\/2018\/09\/26\/%e4%bb%a4%e4%ba%ba%e6%8d%89%e6%91%b8%e4%b8%8d%e9%80%8f%e7%9a%84%e6%b5%81%e6%84%9f%e5%b9%bd%e7%81%b5\/"},"modified":"2018-09-26T09:51:01","modified_gmt":"2018-09-26T01:51:01","slug":"%e4%bb%a4%e4%ba%ba%e6%8d%89%e6%91%b8%e4%b8%8d%e9%80%8f%e7%9a%84%e6%b5%81%e6%84%9f%e5%b9%bd%e7%81%b5","status":"publish","type":"post","link":"https:\/\/www.05921.net\/index.php\/48619\/","title":{"rendered":"\u4ee4\u4eba\u6349\u6478\u4e0d\u900f\u7684\u6d41\u611f\u201c\u5e7d\u7075\u201d"},"content":{"rendered":"<div class=\"bpp-post-content\">\n<p style=\"white-space: normal;\"><span style=\"line-height: 0px;\">\u200d\u200d<\/span><span style=\"font-size: 18.018px;line-height: 0px;\">\u200d<a href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MzAwOTExNzg4Nw==&amp;mid=2657590253&amp;idx=1&amp;sn=af64055348b35e9185b67c634d7ef95c&amp;chksm=80f7b23db7803b2bc868baa456f16ab2329ba355b97bce33703e32440ef4260a6f34c1ea970a&amp;scene=21#wechat_redirect\" target=\"_blank\" style=\"text-align: center;\"><\/a><a href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MzAwOTExNzg4Nw==&amp;mid=2657590253&amp;idx=1&amp;sn=af64055348b35e9185b67c634d7ef95c&amp;chksm=80f7b23db7803b2bc868baa456f16ab2329ba355b97bce33703e32440ef4260a6f34c1ea970a&amp;scene=21#wechat_redirect\" target=\"_blank\" style=\"text-align: center;\"><span class=\"js_jump_icon h5_image_link\"  style=\"top: auto;left: auto;right: auto;bottom: auto;\"><img class=\"\"          style=\"height: 116px;width: 558px;top: auto;left: auto;right: auto;bottom: auto;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/09\/0-1537926659.jpeg\" alt=\"\u4ee4\u4eba\u6349\u6478\u4e0d\u900f\u7684\u6d41\u611f\u201c\u5e7d\u7075\u201d\" title=\"\u4ee4\u4eba\u6349\u6478\u4e0d\u900f\u7684\u6d41\u611f\u201c\u5e7d\u7075\u201d\"  \/><\/span><\/a><\/span><a href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MzAwOTExNzg4Nw==&amp;mid=2657574730&amp;idx=1&amp;sn=7001a26433acb77dcdd5629f27cd8b20&amp;chksm=80f7769ab780ff8cedab5baefd9bc7a02dd18b2191cd29afb2d190e8ea149564133c9437e7d5&amp;scene=21#wechat_redirect\" target=\"_blank\"><\/a><\/p>\n<p style=\"white-space: normal;line-height: normal;\"><br  \/><\/p>\n<p style=\"text-align: justify;line-height: 1.75em;\"><span style=\"font-size: 18px;\">\u9a6c\u4e0a\u8981\u8fdb\u5165\u79cb\u5929\uff0c\u8eab\u8fb9\u6253\u55b7\u568f\u3001\u6d41\u9f3b\u6d95\u7684\u4eba\u9010\u6e10\u589e\u591a\uff0c\u65b0\u4e00\u8f6e\u7684\u6d41\u611f\u5b63\u53ef\u80fd\u5df2\u7ecf\u62c9\u5f00\u4e86\u5e8f\u5e55\u3002\u8001\u4eba\u548c\u513f\u7ae5\u66f4\u5bb9\u6613\u60a3\u4e0a\u6d41\u611f\uff0c\u56e0\u6b64\u5927\u591a\u6570\u56fd\u5bb6\u7684\u536b\u751f\u7ba1\u7406\u90e8\u95e8\u90fd\u63a8\u8350\u7ed9\u8001\u4eba\u548c\u513f\u7ae5\u53ca\u65f6\u6ce8\u5c04\u6d41\u611f\u75ab\u82d7\u3002<strong>\u6d41\u611f\u75ab\u82d7<\/strong>\u4e3b\u8981\u8d77\u4f5c\u7528\u7684\u6210\u5206\u5b9e\u9645\u4e0a\u662f\u706d\u6d3b\u7684\u6d41\u611f\u75c5\u6bd2\uff0c\u7528\u5931\u53bb\u6d3b\u6027\u7684\u75c5\u6bd2\u6765\u6a21\u62df\u771f\u6b63\u7684\u75c5\u6bd2\u653b\u51fb\uff0c\u8ba9\u4eba\u4f53\u7684\u514d\u75ab\u7cfb\u7edf\u505a\u51fa\u54cd\u5e94\u3002\u83b7\u5f97\u80dc\u5229\u7684\u514d\u75ab\u7ec6\u80de\u4f1a\u201c\u8bb0\u4f4f\u201d\u8fd9\u4e9b\u75c5\u6bd2\uff0c\u5f53\u5b83\u4eec\u518d\u4e00\u6b21\u4fb5\u5165\u4f53\u5185\u65f6\u5c31\u4f1a\u7acb\u523b\u6fc0\u6d3b\u514d\u75ab\u7cfb\u7edf\u6740\u6b7b\u75c5\u6bd2\u3002\u4f46\u662f\uff0c\u6d41\u611f\u75c5\u6bd2\u5f88\u5bb9\u6613\u53d1\u751f\u53d8\u5f02\uff0c\u8fd9\u79cd\u60c5\u51b5\u4e0b\uff0c\u514d\u75ab\u7cfb\u7edf\u5bf9\u6b64\u524d\u75c5\u6bd2\u7684\u201c\u8bb0\u5fc6\u201d\u5c31\u7528\u5904\u4e0d\u5927\u4e86\u3002\u8fd9\u4e5f\u80fd\u89e3\u91ca\u4e3a\u4ec0\u4e48\u5e02\u9762\u4e0a\u6ca1\u6709\u4e00\u79cd\u53ef\u62b5\u6297\u6240\u6709\u6d41\u611f\u75c5\u6bd2\u7c7b\u578b\u7684\u75ab\u82d7\uff0c\u4ee5\u53ca\u4e3a\u4ec0\u4e48\u6bcf\u5e74\u75ab\u82d7\u9488\u5bf9\u7684\u75c5\u6bd2\u7c7b\u578b\u53ef\u80fd\u90fd\u4e0d\u76f8\u540c\u3002\u4ee52017-2018\u5e74\u7f8e\u56fd\u7684\u6d41\u611f\u5b63\u4e3a\u4f8b\uff0c\u63a5\u79cd\u75ab\u82d7\u7684\u4eba\u611f\u67d3\u6d41\u611f\u7684\u53ef\u80fd\u6027\u6bd4\u672a\u63a5\u79cd\u75ab\u82d7\u7684\u4eba\u4ec5\u4f4e36%\u3002<\/span><\/p>\n<p style=\"text-align: center;\"><img class=\"\"       style=\"\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/09\/8-1537926659.jpeg\" alt=\"\u4ee4\u4eba\u6349\u6478\u4e0d\u900f\u7684\u6d41\u611f\u201c\u5e7d\u7075\u201d\" title=\"\u4ee4\u4eba\u6349\u6478\u4e0d\u900f\u7684\u6d41\u611f\u201c\u5e7d\u7075\u201d\"  \/><\/p>\n<p style=\"text-align: center;line-height: 1.75em;\"><span style=\"font-size: 16px;color: rgb(136, 136, 136);\">\u56fe\u7247\u6765\u6e90\u4e8e\u7f51\u7edc<\/span><\/p>\n<p><br  \/><\/p>\n<p style=\"text-align: justify;line-height: 1.75em;\"><span style=\"font-size: 18px;\">\u6d41\u611f\u75c5\u6bd2\u7684\u591a\u53d8\u8fd8\u4f1a\u7ed9\u4eba\u7c7b\u8eab\u4f53\u5e26\u6765\u610f\u60f3\u4e0d\u5230\u7684\u5f71\u54cd\u3002\u5bc6\u6b47\u6839\u5927\u5b66\u7684\u75c5\u6bd2\u5b66\u5bb6\u548c\u6d41\u884c\u75c5\u5b66\u5bb6Thomas Francis\u572820\u4e16\u7eaa40\u5e74\u4ee3\u548c50\u5e74\u4ee3\u7684\u7814\u7a76\u8868\u660e\uff0c\u76f8\u6bd4\u4e8e\u6b64\u540e\u63a5\u89e6\u5230\u7684\u6d41\u611f\u75c5\u6bd2\u7c7b\u578b\uff0c\u4eba\u4eec\u5bf9\u4ed6\u4eec\u9047\u5230\u7684\u7b2c\u4e00\u79cd\u6d41\u611f\u75c5\u6bd2\u4f1a\u4ea7\u751f\u66f4\u5f3a\u7684\u6297\u4f53\u54cd\u5e94&nbsp;<\/span><span style=\"font-size: 14px;\"><sup>[1]<\/sup><\/span><span style=\"font-size: 18px;\">\u3002\u4e5f\u5c31\u662f\u8bf4\uff0c\u4eba\u4f53\u514d\u75ab\u7cfb\u7edf\u5bf9\u7b2c\u4e00\u6b21\u63a5\u89e6\u5230\u7684\u6d41\u611f\u75c5\u6bd2\u201c\u8bb0\u5fc6\u201d\u66f4\u52a0\u6df1\u523b\u3002Thomas Francis\u5c06\u8fd9\u79cd\u73b0\u8c61\u79f0\u4e4b\u4e3a\u201c<strong>\u514d\u75ab\u5370\u8bb0<\/strong>\uff08immunological imprinting\uff09\u201d\u3002\u5982\u679c\u80fd\u5f7b\u5e95\u5f04\u6e05\u695a\u514d\u75ab\u5370\u8bb0\u7684\u673a\u7406\u5c31\u53ef\u80fd\u89e3\u91ca\u4e3a\u4ec0\u4e48\u6d41\u611f\u75ab\u82d7\u6548\u679c\u4e0d\u7406\u60f3\uff0c\u4ece\u800c\u6539\u8fdb\u75ab\u82d7\u3002\u5bbe\u5915\u6cd5\u5c3c\u4e9a\u5927\u5b66\u7684\u75c5\u6bd2\u514d\u75ab\u5b66\u5bb6Scott Hensley\u751a\u81f3\u8ba4\u4e3a\u4e86\u89e3\u514d\u75ab\u5370\u8bb0\u7684\u4ea7\u751f\u673a\u7406\u80fd\u591f\u5e2e\u52a9\u7814\u7a76\u8005\u7814\u53d1\u4e00\u79cd\u5bf9\u6297\u4ee5\u5f80\u51fa\u73b0\u7684\u5404\u79cd\u6d41\u611f\u75c5\u6bd2\u7684\u5e7f\u8c31\u6297\u6d41\u611f\u75ab\u82d7 <\/span><span style=\"text-align: justify;font-size: 14px;\"><sup>[2]<\/sup><\/span><span style=\"text-align: justify;font-size: 18px;\">\u3002<\/span><\/p>\n<p><br  \/><\/p>\n<p style=\"text-align: justify;line-height: 1.75em;\"><span style=\"font-size: 18px;\">\u514d\u75ab\u5370\u8bb0\u7684\u5f71\u54cd\u8fd8\u4e0d\u6b62\u4e8e\u6b64\u3002\u8d8a\u6765\u8d8a\u591a\u7684\u8bc1\u636e\u8868\u660e\uff0c\u6709\u4e9b\u4eba\u5728\u81f4\u547d\u7684\u6d41\u611f\u5927\u6d41\u884c\u4e2d\u66f4\u5bb9\u6613\u88ab\u611f\u67d3\uff0c\u6216\u8005\u66f4\u5bb9\u6613\u53d1\u5c55\u4e3a\u6bd4\u8f83\u4e25\u91cd\u7684\u75c5\u60c5\uff0c\u539f\u56e0\u662f\u4ed6\u4eec\u5c0f\u65f6\u5019\u7b2c\u4e00\u6b21\u63a5\u89e6\u7684\u662f\u4e0d\u540c\u79cd\u7c7b\u7684\u6d41\u611f\u75c5\u6bd2\u3002\u7814\u7a76\u4eba\u5458\u731c\u60f3\uff0c\u8fd9\u5c31\u662f\u4e3a\u4ec0\u4e48100\u5e74\u524d\u897f\u73ed\u7259\u5927\u6d41\u611f\u4e2d\u5e74\u8f7b\u4eba\u6b7b\u4ea1\u7387\u66f4\u9ad8\u7684\u539f\u56e0 <span style=\"text-align: justify;font-size: 14px;\"><sup>[3]<\/sup><\/span><span style=\"text-align: justify;font-size: 18px;\">\u3002<\/span>\u897f\u73ed\u7259\u5927\u6d41\u611f\u662f\u5168\u7403\u5386\u53f2\u4e0a\u6700\u4e25\u91cd\u7684\u6d41\u611f\u75ab\u60c5\u4e4b\u4e00\uff0c\u66fe\u5bfc\u81f4\u5927\u69825000\u4e07\u4eba\u6b7b\u4ea1\u3002<\/span><\/p>\n<p style=\"text-align: center;\"><img class=\"\"       style=\"\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/09\/3-1537926660.jpeg\" alt=\"\u4ee4\u4eba\u6349\u6478\u4e0d\u900f\u7684\u6d41\u611f\u201c\u5e7d\u7075\u201d\" title=\"\u4ee4\u4eba\u6349\u6478\u4e0d\u900f\u7684\u6d41\u611f\u201c\u5e7d\u7075\u201d\"  \/><\/p>\n<p style=\"text-align: justify;line-height: 1.75em;\"><span style=\"font-size: 16px;color: rgb(136, 136, 136);\">1918\u5e74\u897f\u73ed\u7259\u5927\u6d41\u611f\u671f\u95f4\u7279\u5b9a\u5e74\u9f84\u6bb5\u7684\u5e74\u8d85\u989d\u6b7b\u4ea1\u7387\u3002\u56fe\u7247\u6765\u6e90\uff1a<em>Clin. Infect. Dis.<\/em>&nbsp;<\/span><span style=\"text-align: justify;color: rgb(136, 136, 136);font-size: 14px;\"><sup>[2]<\/sup><\/span><\/p>\n<p><br  \/><\/p>\n<p style=\"text-align: justify;line-height: 1.75em;\"><span style=\"font-size: 18px;\">\u4eca\u5e744\u6708\uff0c\u7f8e\u56fd\u56fd\u7acb\u536b\u751f\u7814\u7a76\u9662\u8fc7\u654f\u4e0e\u611f\u67d3\u7814\u7a76\u6240\uff08NIAID\uff09\u53f7\u53ec\u7814\u7a76\u4eba\u5458\u63a2\u7a76\u514d\u75ab\u5370\u8bb0\u7684\u5f71\u54cd\uff0c\u4f5c\u4e3a\u7814\u7a76\u5e7f\u8c31\u6297\u6d41\u611f\u75ab\u82d7\u7684\u4e00\u90e8\u5206<span style=\"text-align: justify;font-size: 14px;\"><sup>[4]<\/sup><\/span><span style=\"text-align: justify;font-size: 18px;\">\u3002<\/span>\u8be5\u673a\u6784\u8ba1\u5212\u6295\u8d44500\u4e07\u7f8e\u5143\u62db\u52df\u5a74\u513f\uff0c\u76d1\u6d4b\u4ece\u4ed6\u4eec\u51fa\u751f\u5230\u81f3\u5c11\u7ecf\u5386\u4e09\u4e2a\u6d41\u611f\u5b63\uff0c\u4ece\u5206\u5b50\u6c34\u5e73\u4e0a\u63a2\u7a76\u514d\u75ab\u7cfb\u7edf\u5bf9\u4e8e\u9996\u6b21\u53ca\u540e\u7eed\u6d41\u611f\u75c5\u6bd2\u611f\u67d3\u4ee5\u53ca\u75ab\u82d7\u63a5\u79cd\u7684\u54cd\u5e94\u3002<\/span><\/p>\n<p><br  \/><\/p>\n<p style=\"text-align: justify;line-height: 1.75em;\"><span style=\"font-size: 18px;\">\u5bfc\u81f4\u4eba\u7c7b\u60a3\u75c5\u7684\u6d41\u611f\u75c5\u6bd2\u6709\u5f88\u591a\u4e9a\u578b\uff0c\u4ee5\u75c5\u6bd2\u9897\u7c92\u8868\u9762\u4e0a\u7684\u4e0d\u540c\u86cb\u767d\u8d28\u6765\u547d\u540d\u3002\u76ee\u524d\u5df2\u7ecf\u77e5\u9053\uff0c\u6d41\u611f\u75c5\u6bd2\u8868\u9762\u5b58\u572818\u79cd\u8840\u7ec6\u80de\u51dd\u96c6\u7d20\uff08haemagglutinin, HA\uff09\u86cb\u767d\u548c11\u79cd\u795e\u7ecf\u6c28\u9178\u9176\uff08neuraminidase, NA\uff09\u86cb\u767d\u8d28\u3002\u6bcf\u79cd\u75c5\u6bd2\u4e9a\u578b\u90fd\u5177\u6709HA\u548cNA\u53d8\u4f53\uff0c\u5c06\u5b83\u4eec\u8fde\u8d77\u6765\u5c31\u80fd\u7ed9\u6bcf\u4e2a\u6d41\u611f\u75c5\u6bd2\u4e9a\u578b\u547d\u540d\uff0c\u4f8b\u5982H1N1\u6216H3N2\u3002<\/span><\/p>\n<p style=\"text-align: center;\"><img class=\"\"       style=\"\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/09\/1-1537926660.jpeg\" alt=\"\u4ee4\u4eba\u6349\u6478\u4e0d\u900f\u7684\u6d41\u611f\u201c\u5e7d\u7075\u201d\" title=\"\u4ee4\u4eba\u6349\u6478\u4e0d\u900f\u7684\u6d41\u611f\u201c\u5e7d\u7075\u201d\"  \/><\/p>\n<p style=\"text-align: justify;line-height: 1.75em;\"><span style=\"font-size: 16px;color: rgb(136, 136, 136);\">\u6d41\u611f\u75c5\u6bd2\u6a21\u578b\u3002\u56fe\u7247\u6765\u6e90\u4e8e\u7f51\u7edc<\/span><\/p>\n<p><br  \/><\/p>\n<p style=\"text-align: justify;line-height: 1.75em;\"><span style=\"font-size: 18px;\">2016\u5e74Gostic\u548c\u5979\u7684\u540c\u4e8b\u5728<em>Science<\/em>\u4e0a\u53d1\u8868\u4e86\u4e00\u7bc7\u6587\u7ae0\uff0c\u5206\u6790\u4e86\u76ee\u524d\u80fd\u611f\u67d3\u4eba\u4f53\u7684\u4e24\u79cd\u79bd\u6d41\u611f\u75c5\u6bd2\u4e9a\u578b\uff08H5N1\u548cH7N9\uff09<span style=\"text-align: justify;font-size: 14px;\"><sup>[5]<\/sup><\/span><span style=\"text-align: justify;font-size: 18px;\">\u3002<\/span>\u8fd9\u4e24\u79cd\u75c5\u6bd2\u80fd\u591f\u611f\u67d3\u4e0d\u540c\u5e74\u9f84\u6bb5\u7684\u4eba\uff0c\u6bd4\u5982H5N1\u4e3b\u8981\u611f\u67d3\u5e74\u8f7b\u4eba\uff0c\u800c\u6709\u5173H7N9\u7684\u60a3\u8005\u51e0\u4e4e\u90fd\u662f\u8001\u5e74\u4eba\u3002\u901a\u8fc7\u5206\u6790\u60a3\u8005\u7684\u51fa\u751f\u5e74\u6708\uff0c\u4ed6\u4eec\u53d1\u73b0\u60a3\u8005\u5bf9\u75c5\u6bd2\u7684\u6613\u611f\u6027\u57281968\u5e74\u8fd9\u91cc\u53d1\u751f\u4e86\u7a81\u7136\u7684\u53d8\u5316\uff0c1968\u4e4b\u524d\u51fa\u751f\u7684\u4eba\u66f4\u5bb9\u6613\u611f\u67d3H7N9\uff0c\u800c1968\u4e4b\u540e\u51fa\u751f\u7684\u4eba\u66f4\u5bb9\u6613\u611f\u67d3H5N1\u3002<\/span><\/p>\n<p><br  \/><\/p>\n<p style=\"text-align: justify;line-height: 1.75em;\"><span style=\"font-size: 18px;\">\u8fd9\u8ba9\u7814\u7a76\u8005\u611f\u89c9\u5230\u975e\u5e38\u5947\u602a\uff0c\u8fd9\u4e9b\u60a3\u8005\u6b64\u524d\u90fd\u6ca1\u6709\u9047\u5230H5N1\u548cH7N9\u4e2d\u7684\u4efb\u4f55\u4e00\u79cd\uff0c\u4e3a\u4ec0\u4e48\u4f1a\u6709\u8fd9\u4e48\u5927\u7684\u533a\u522b\u3002\u539f\u6765\uff0c1968\u5e74\u524d\u540e\u6d41\u611f\u53d1\u751f\u4e86\u8f83\u5927\u53d8\u5316\u3002\u57281968\u5e74\u4e4b\u524d\uff0c\u6d41\u884c\u7684\u662fH1N1\u548cH2N2\u4e9a\u578b\uff0c\u90a3\u65f6\u5019\u51fa\u751f\u7684\u4eba\u9996\u6b21\u78b0\u5230\u7684\u57fa\u672c\u4e0a\u4e5f\u5c31\u662f\u8fd9\u4e24\u4e2a\u4e9a\u578b\uff0c\u5e26\u6709\u5b83\u4eec\u7684\u514d\u75ab\u5370\u8bb0\u3002\u800c\u8fd9\u4e24\u4e2a\u4e9a\u578b\u4e0eH5N1\u6bd4\u8f83\u76f8\u4f3c\uff0c\u56e0\u6b64\uff0c\u6b64\u524d\u7684\u514d\u75ab\u5370\u8ff9\u4f7f\u5f971968\u5e74\u524d\u51fa\u751f\u7684\u4eba\u66f4\u4e0d\u5bb9\u6613\u611f\u67d3H5N1\u3002\u57281968\u5e74\u4e4b\u540e\uff0c\u4e00\u5207\u90fd\u53d1\u751f\u4e86\u53d8\u5316\uff0cH3N2\u5f00\u59cb\u5927\u6d41\u884c\uff0c\u5e76\u6210\u4e3a\u552f\u4e00\u7684\u5b63\u8282\u6027\u4e9a\u578b\u3002\u56e0\u6b64\uff0c\u5728\u90a3\u4e4b\u540e\u51fa\u751f\u7684\u5927\u591a\u6570\u4eba\u90fd\u5e26\u6709H3N2\u4e9a\u578b\u7684\u514d\u75ab\u5370\u8bb0\u3002\u800cH3N2\u4e0eH7N9\u6bd4\u8f83\u76f8\u4f3c\uff0c\u8fd9\u5c31\u4f7f\u5f971968\u5e74\u4ee5\u540e\u51fa\u751f\u7684\u4eba\u66f4\u5bb9\u6613\u62b5\u6297H7N9\u7684\u611f\u67d3\u3002\u8be5\u53d1\u73b0\u8bc1\u660e\u5bf9\u67d0\u4e00\u79cd\u75c5\u6bd2\u4ea7\u751f\u514d\u75ab\u5370\u8bb0\u540e\u53ef\u80fd\u5bf9\u540c\u4e00\u7c7b\u7684\u65b0\u4e9a\u578b\u75c5\u6bd2\u4ea7\u751f\u62b5\u6297\u529b\uff0c\u8fd9\u4e0e\u8bb8\u591a\u516c\u5171\u536b\u751f\u4e13\u5bb6\u63d0\u51fa\u7684\u5047\u8bbe\u76f8\u6096\uff0c\u5373\u6d41\u611f\u75ab\u60c5\u901a\u5e38\u662f\u5728\u65b0\u4e9a\u578b\u6d41\u611f\u75c5\u6bd2\u51fa\u73b0\u65f6\u624d\u4f1a\u5f15\u8d77\uff0c\u5e76\u4e14\u5927\u591a\u6570\u4eba\u5bf9\u8be5\u75c5\u6bd2\u51e0\u4e4e\u6216\u8005\u6839\u672c\u6ca1\u6709\u62b5\u6297\u529b\u3002\u968f\u540e\u4f5c\u8005\u8fdb\u884c\u4e86\u6a21\u578b\u5206\u6790\uff0c\u53d1\u73b0\u513f\u7ae5\u65f6\u671f\u7684\u514d\u75ab\u5370\u8bb0\u53ef\u4ee5\u907f\u514d80%\u7684\u4eba\u5728\u79bd\u6d41\u611f\u75ab\u60c5\u4e2d\u6b7b\u4ea1\u3002Scott Hensley\u8ba4\u4e3a\u76ee\u524d\u7684\u9996\u8981\u4efb\u52a1\u662f\u660e\u767d\u4eba\u4f53\u7b2c\u4e00\u6b21\u53d7\u5230\u75c5\u6bd2\u611f\u67d3\u65f6\u5230\u5e95\u5982\u4f55\u4ea7\u751f\u514d\u75ab\u5370\u8bb0\u3002<\/span><\/p>\n<p style=\"text-align: center;\"><img class=\"\"       style=\"\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/09\/8-1537926660.jpeg\" alt=\"\u4ee4\u4eba\u6349\u6478\u4e0d\u900f\u7684\u6d41\u611f\u201c\u5e7d\u7075\u201d\" title=\"\u4ee4\u4eba\u6349\u6478\u4e0d\u900f\u7684\u6d41\u611f\u201c\u5e7d\u7075\u201d\"  \/><\/p>\n<p style=\"text-align: justify;line-height: 1.75em;\"><span style=\"font-size: 16px;color: rgb(136, 136, 136);\">\u5386\u5e74\u6765\u5f15\u8d77\u4e25\u91cd\u6d41\u611f\u75ab\u60c5\u7684\u4e0d\u540c\u75c5\u6bd2\u4ee5\u53ca\u6bcf\u5e74\u5bfc\u81f4\u7684\u6b7b\u4ea1\u4eba\u6570\u3002\u56fe\u7247\u6765\u6e90\uff1a<em>Nature&nbsp;<\/em><\/span><span style=\"text-align: justify;color: rgb(136, 136, 136);font-size: 12px;\"><sup>[2]<\/sup><\/span><\/p>\n<p><br  \/><\/p>\n<p style=\"text-align: justify;line-height: 1.75em;\"><span style=\"font-size: 18px;\">\u5728\u8fc7\u53bb\u7684\u5341\u5e74\u4e2d\uff0c\u7814\u7a76\u4eba\u5458\u5df2\u7ecf\u5f00\u53d1\u51fa\u4e00\u7cfb\u5217\u6280\u672f\u4ece\u5206\u5b50\u6c34\u5e73\u4e0a\u7814\u7a76\u514d\u75ab\u5370\u8bb0\u7684\u4ea7\u751f\u3002\u4f8b\u5982\u7814\u7a76\u4eba\u5458\u73b0\u5728\u80fd\u591f\u5bf9\u6210\u5343\u4e0a\u4e07\u7684\u7ec6\u80de\u8fdb\u884c\u5206\u7c7b\u548c\u5206\u6790\uff0c\u5229\u7528\u5355\u7ec6\u80de\u6d4b\u5e8f\u6765\u7814\u7a76\u673a\u4f53\u7b2c\u4e00\u6b21\u53d7\u5230\u75c5\u6bd2\u611f\u67d3\u65f6\u514d\u75ab\u54cd\u5e94\u4e2d\u7684\u4e3b\u8981\u53c2\u4e0e\u8005\u3002\u4e00\u65e6\u8fd9\u4e9b\u673a\u5236\u80fd\u88ab\u6e05\u695a\u5730\u7406\u89e3\uff0c\u5c31\u6709\u5e0c\u671b\u6307\u5bfc\u540e\u7eed\u5e7f\u8c31\u6297\u6d41\u611f\u75ab\u82d7\u7684\u7814\u53d1\u3002\u4e0e\u62e5\u6709\u51e0\u5341\u4e07\u4ebf\u4e2a\u7ec6\u80de\u7684\u4eba\u7c7b\u76f8\u6bd4\uff0c\u75c5\u6bd2\u7684\u7ed3\u6784\u7b80\u5355\u7684\u53ef\u601c\uff0c\u4f46\u5c31\u662f\u8fd9\u4e48\u7b80\u5355\u7684\u751f\u547d\u5f62\u5f0f\u5374\u8ba9\u81ea\u8be9\u4e07\u7269\u4e4b\u7075\u7684\u4eba\u7c7b\u5e38\u5e38\u675f\u624b\u65e0\u7b56\u3002\u4eba\u7c7b\u60f3\u8981\u627e\u5230\u5bf9\u6297\u75c5\u6bd2\u611f\u67d3\u7684\u6709\u6548\u65b9\u6cd5\uff0c\u79d1\u5b66\u5bb6\u4eec\u8d23\u65e0\u65c1\u8d37\u3002<\/span><\/p>\n<p><br  \/><\/p>\n<p style=\"text-align: justify;line-height: 1.75em;\"><span style=\"font-size: 14px;\">\u53c2\u8003\u8d44\u6599\uff1a<\/span><\/p>\n<p style=\"text-align: justify;line-height: 1.75em;\"><span style=\"font-size: 14px;\">1. On the doctrine of original antigenic sin. <em>Proc. Am. Philos. Soc<\/em>., <strong>1960<\/strong>, <em>104<\/em>, 572\u2013578&nbsp;<\/span><\/p>\n<p style=\"text-align: justify;line-height: 1.75em;\"><span style=\"font-size: 14px;\">2. https:\/\/www.nature.com\/articles\/d41586-018-05889-1<\/span><\/p>\n<p style=\"text-align: justify;line-height: 1.75em;\"><span style=\"font-size: 14px;\">3. Observations on Mortality during the 1918 Influenza Pandemic. <em>Clin. Infect. Dis.<\/em>, <strong>2001<\/strong>, <em>33<\/em>, 1375\u20131378, DOI: 10.1086\/322662<\/span><\/p>\n<p style=\"text-align: justify;line-height: 1.75em;\"><span style=\"font-size: 14px;\">4. A Universal Influenza Vaccine: The Strategic Plan for the National Institute of Allergy and Infectious Diseases. <em>J. Infect. Dis<\/em>., <strong>2018<\/strong>, <em>218<\/em>, 347\u2013354, DOI: 10.1093\/infdis\/jiy103<\/span><\/p>\n<p style=\"text-align: justify;line-height: 1.75em;\"><span style=\"font-size: 14px;\">5. Potent protection against H5N1 and H7N9 influenza via childhood hemagglutinin imprinting. <em>Science<\/em>, <strong>2016<\/strong>, <em>354<\/em>, 722-726, DOI: 10.1126\/science.aag1322<\/span><\/p>\n<p><br  \/><\/p>\n<p style=\"text-align: right;\">\uff08\u672c\u6587\u7531<strong>Sunshine<\/strong>\u4f9b\u7a3f\uff09<\/p>\n<p><br  \/><\/p>\n<section style=\"white-space: normal;\">\n<section class=\"Powered-by-XIUMI V5\" >\n<section class=\"\">\n<section class=\"\">\n<p style=\"text-align: center;\"><a href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MzAwOTExNzg4Nw==&amp;mid=2657590253&amp;idx=1&amp;sn=af64055348b35e9185b67c634d7ef95c&amp;chksm=80f7b23db7803b2bc868baa456f16ab2329ba355b97bce33703e32440ef4260a6f34c1ea970a&amp;scene=21#wechat_redirect\" target=\"_blank\" style=\"font-size: 18.018px;\"><\/a><a href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MzAwOTExNzg4Nw==&amp;mid=2657590253&amp;idx=1&amp;sn=af64055348b35e9185b67c634d7ef95c&amp;chksm=80f7b23db7803b2bc868baa456f16ab2329ba355b97bce33703e32440ef4260a6f34c1ea970a&amp;scene=21#wechat_redirect\" target=\"_blank\" style=\"font-size: 18.018px;\"><span class=\"js_jump_icon h5_image_link\"  style=\"top: auto;left: auto;right: auto;bottom: auto;\"><img class=\"\"          style=\"height: 116px;width: 558px;top: auto;left: auto;right: auto;bottom: auto;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/09\/7-1537926661.jpeg\" alt=\"\u4ee4\u4eba\u6349\u6478\u4e0d\u900f\u7684\u6d41\u611f\u201c\u5e7d\u7075\u201d\" title=\"\u4ee4\u4eba\u6349\u6478\u4e0d\u900f\u7684\u6d41\u611f\u201c\u5e7d\u7075\u201d\"  \/><\/span><\/a><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<p style=\"white-space: normal;\"><br  \/><\/p>\n<p style=\"white-space: normal;line-height: 25.6px;text-align: center;\"><img      style=\"font-size: 18px;background-color: rgb(255, 255, 255);line-height: 25.6px;width: 556px;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/09\/4-1537926661.png\" alt=\"\u4ee4\u4eba\u6349\u6478\u4e0d\u900f\u7684\u6d41\u611f\u201c\u5e7d\u7075\u201d\" title=\"\u4ee4\u4eba\u6349\u6478\u4e0d\u900f\u7684\u6d41\u611f\u201c\u5e7d\u7075\u201d\"  \/><\/p>\n<section style=\"white-space: normal;background-color: rgb(255, 255, 255);box-sizing: border-box;\">\n<section class=\"Powered-by-XIUMI V5\"  style=\"box-sizing: border-box;\">\n<section class=\"\" style=\"margin-top: 10px;margin-bottom: 10px;box-sizing: border-box;\">\n<section class=\"\" style=\"height: 16px;box-sizing: border-box;\">\n<section style=\"height: 15.9961px;width: 24px;float: left;border-top: 6px solid rgb(9, 158, 206);border-left: 6px solid rgb(9, 158, 206);border-right-color: rgb(9, 158, 206);border-bottom-color: rgb(9, 158, 206);box-sizing: border-box;\"><\/section>\n<section style=\"height: 15.9961px;width: 24px;float: right;border-top: 6px solid rgb(9, 158, 206);border-right: 6px solid rgb(9, 158, 206);border-bottom-color: rgb(9, 158, 206);border-left-color: rgb(9, 158, 206);box-sizing: border-box;\"><\/section>\n<section style=\"display: inline-block;color: transparent;clear: both;box-sizing: border-box;\"><\/section>\n<\/section>\n<section class=\"\" style=\"margin: -13px 3px;padding: 12px;border-width: 1px;border-style: solid;border-color: rgb(9, 158, 206);border-radius: 6px;word-wrap: break-word;box-sizing: border-box;\">\n<section class=\"Powered-by-XIUMI V5\"  style=\"box-sizing: border-box;\">\n<section class=\"\" style=\"box-sizing: border-box;\">\n<section class=\"\" style=\"box-sizing: border-box;\">\n<p style=\"box-sizing: border-box;\"><span style=\"font-size: 18px;\">\u672c\u6587\u7248\u6743\u5c5e\u4e8e<span style=\"color: rgb(9, 158, 206);box-sizing: border-box;\"><strong style=\"box-sizing: border-box;\">X-MOL<\/strong><\/span>\uff08x-mol.com\uff09\uff0c\u672a\u7ecf\u8bb8\u53ef\u8c22\u7edd\u8f6c\u8f7d\uff01\u6b22\u8fce\u8bfb\u8005\u670b\u53cb\u4eec\u5206\u4eab\u5230\u670b\u53cb\u5708or\u5fae\u535a\uff01<\/span><\/p>\n<p style=\"box-sizing: border-box;\"><br style=\"box-sizing: border-box;\"  \/><\/p>\n<p style=\"box-sizing: border-box;\"><span style=\"font-size: 18px;\"><span style=\"color: rgb(9, 158, 206);box-sizing: border-box;\"><strong style=\"box-sizing: border-box;\">\u957f\u6309<\/strong><\/span>\u4e0b\u56fe<strong style=\"box-sizing: border-box;\">\u8bc6\u522b\u56fe\u4e2d\u4e8c\u7ef4\u7801<\/strong>\uff0c\u8f7b\u677e\u5173\u6ce8\u6211\u4eec\uff01<\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"Powered-by-XIUMI V5\"  style=\"box-sizing: border-box;\">\n<p style=\"margin-top: 10px;margin-bottom: 10px;text-align: center;box-sizing: border-box;\"><img class=\"\"     style=\"vertical-align: middle;box-sizing: border-box;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/09\/6-1537926661.jpeg\" alt=\"\u4ee4\u4eba\u6349\u6478\u4e0d\u900f\u7684\u6d41\u611f\u201c\u5e7d\u7075\u201d\" title=\"\u4ee4\u4eba\u6349\u6478\u4e0d\u900f\u7684\u6d41\u611f\u201c\u5e7d\u7075\u201d\"  \/><\/p>\n<\/section>\n<\/section>\n<section class=\"\" style=\"height: 16px;box-sizing: border-box;\">\n<section style=\"height: 15.9961px;width: 24px;float: left;border-bottom: 6px solid rgb(9, 158, 206);border-left: 6px solid rgb(9, 158, 206);border-top-color: rgb(9, 158, 206);border-right-color: rgb(9, 158, 206);box-sizing: border-box;\"><\/section>\n<section style=\"height: 15.9961px;width: 24px;float: right;border-bottom: 6px solid rgb(9, 158, 206);border-right: 6px solid rgb(9, 158, 206);border-top-color: rgb(9, 158, 206);border-left-color: rgb(9, 158, 206);box-sizing: border-box;\"><\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"white-space: normal;\">\n<section >\n<section>\n<section>\n<section>\n<section >\n<section>\n<section>\n<p style=\"text-align: center;\"><br  \/><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<p style=\"white-space: normal;line-height: 25.6px;font-size: 18.018px;max-width: 100%;min-height: 1em;color: rgb(62, 62, 62);background-color: rgb(255, 255, 255);box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;color: rgb(0, 0, 0);font-size: 18px;box-sizing: border-box !important;word-wrap: break-word !important;\">\u70b9\u51fb\u201c<span style=\"max-width: 100%;color: rgb(0, 122, 170);\">\u9605\u8bfb\u539f\u6587<\/span>\u201d\uff0c\u67e5\u770b&nbsp;<strong>\u5316\u5b66 \u2022 \u6750\u6599&nbsp;<\/strong>\u9886\u57df<span style=\"max-width: 100%;background-color: rgb(255, 218, 81);\">\u6240\u6709\u6536\u5f55\u671f\u520a<\/span><\/span><\/p>\n<p style=\"white-space: normal;line-height: 25.6px;font-size: 18.018px;max-width: 100%;min-height: 1em;color: rgb(62, 62, 62);background-color: rgb(255, 255, 255);box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;color: rgb(0, 0, 0);font-size: 14px;box-sizing: border-box !important;word-wrap: break-word !important;\"><\/span><\/p>\n<\/p><\/div>\n","protected":false},"excerpt":{"rendered":"<p>\u200d\u200d\u200d \u9a6c\u4e0a\u8981\u8fdb\u5165\u79cb\u5929\uff0c\u8eab\u8fb9\u6253\u55b7\u568f\u3001\u6d41\u9f3b\u6d95\u7684\u4eba\u9010\u6e10\u589e\u591a\uff0c\u65b0\u4e00\u8f6e\u7684\u6d41\u611f\u5b63\u53ef\u80fd\u5df2\u7ecf\u62c9\u5f00\u4e86\u5e8f\u5e55\u3002\u8001\u4eba\u548c\u513f\u7ae5\u66f4\u5bb9\u6613\u60a3\u4e0a 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