{"id":49072,"date":"2018-09-21T01:00:00","date_gmt":"2018-09-26T01:54:51","guid":{"rendered":"http:\/\/www.05921.net\/index.php\/2018\/09\/26\/%e9%80%9f%e9%80%92-%e8%be%89%e7%91%9e%e8%82%ba%e7%82%8e%e9%93%be%e7%90%83%e8%8f%8c%e7%96%ab%e8%8b%97%e8%8e%b7fda%e7%aa%81%e7%a0%b4%e6%80%a7%e7%96%97%e6%b3%95%e8%ae%a4%e5%ae%9a\/"},"modified":"2018-09-26T09:54:53","modified_gmt":"2018-09-26T01:54:53","slug":"%e9%80%9f%e9%80%92-%e8%be%89%e7%91%9e%e8%82%ba%e7%82%8e%e9%93%be%e7%90%83%e8%8f%8c%e7%96%ab%e8%8b%97%e8%8e%b7fda%e7%aa%81%e7%a0%b4%e6%80%a7%e7%96%97%e6%b3%95%e8%ae%a4%e5%ae%9a","status":"publish","type":"post","link":"https:\/\/www.05921.net\/index.php\/49072\/","title":{"rendered":"\u901f\u9012 | \u8f89\u745e\u80ba\u708e\u94fe\u7403\u83cc\u75ab\u82d7\u83b7FDA\u7a81\u7834\u6027\u7597\u6cd5\u8ba4\u5b9a"},"content":{"rendered":"
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\u258e\u836f\u660e<\/span><\/strong>\u5eb7\u5fb7\/\u62a5\u9053<\/span><\/strong><\/strong><\/span><\/strong><\/strong><\/span><\/strong><\/strong><\/strong><\/span><\/strong><\/strong><\/span><\/strong><\/strong><\/h1>\n

\u4eca\u65e5\uff0c\u8f89\u745e\uff08Pfizer\uff09\u5ba3\u5e03\u5176\u5728\u7814\u5019\u9009\u75ab\u82d7PF-06482077\uff0c\u83b7\u5f97FDA\u6388\u4e88\u7684\u7a81\u7834\u6027\u7597\u6cd5\u8ba4\u5b9a\u3002<\/strong>PF-06482077\u662f\u4e00\u6b3e20\u4ef7\u80ba\u708e\u94fe\u7403\u83cc\u5076\u8054(20vPnC)\u75ab\u82d7\uff0c\u5c06\u7528\u4e8e\u572818\u5c81\u4ee5\u4e0a\u7684\u6210\u4eba\u4e2d\u9884\u9632\u7531\u80ba\u708e\u94fe\u7403\u83cc\u611f\u67d3\u5f15\u8d77\u7684\u80ba\u708e\u548c\u4fb5\u88ad\u6027\u75be\u75c5\u3002\u6b64\u524d\uff0cFDA\u5df2\u4e8e\u53bb\u5e7410\u6708\u6388\u4e88\u8be5\u5019\u9009\u75ab\u82d7\u201c\u5feb\u901f\u901a\u9053\u8d44\u683c\u201d\u3002<\/span><\/p>\n

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\"\u901f\u9012<\/p>\n

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\"\u901f\u9012<\/p>\n

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\u5076\u8054\u75ab\u82d7\uff08conjugate vaccine\uff09\u662f\u901a\u8fc7\u5316\u5b66\u65b9\u6cd5\u5c06\u591a\u7cd6\u6216\u5be1\u7cd6\u6297\u539f\uff0c\u5076\u8054\u5230\u86cb\u767d\u8d28\u8f7d\u4f53\u4e0a\u3002\u5b83\u80fd\u591f\u66f4\u597d\u5730\u523a\u6fc0\u6210\u4eba\u4e0e\u513f\u7ae5\u7684\u514d\u75ab\u53cd\u5e94\uff0c\u4ece\u800c\u4fc3\u4f7fB\u7ec6\u80de\u751f\u4ea7IgG\u6297\u4f53<\/span><\/strong>\u3002\u5076\u8054\u75ab\u82d7\u6709\u671b\u5bf9\u591a\u79cd\u4f20\u67d3\u6027\u75be\u75c5\u7684\u9884\u9632\u4ea7\u751f\u91cd\u8981\u4f5c\u7528\u3002<\/span><\/p>\n


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\u6b64\u6b21\u7a81\u7834\u6027\u7597\u6cd5\u8ba4\u5b9a\u7684\u6388\u4e88\u662f\u57fa\u4e8e\u8be520vPnC\u5019\u9009\u75ab\u82d7\u76842\u671f\u4e34\u5e8a\u8bd5\u9a8c\u7ed3\u679c\u3002\u8fd9\u9879\u968f\u673a\u53cc\u76f2\u76842\u671f\u8bd5\u9a8c\uff0c\u8bc4\u4f30\u4e86\u591a\u4ef7\u80ba\u708e\u94fe\u7403\u83cc\u5076\u8054\u75ab\u82d7\uff0c\u7528\u4e8e60\u81f364\u5c81\u6210\u4eba\u4e2d\u7684\u5b89\u5168\u6027\u548c\u514d\u75ab\u539f\u6027\u3002\u8f89\u745e\u8ba1\u5212\u8fd1\u671f\u516c\u5e03\u8fd9\u4e00\u8bd5\u9a8c\u7684\u5177\u4f53\u7ed3\u679c\uff0c\u5e76\u4e8e\u51e0\u4e2a\u6708\u5185\u5f00\u5c553\u671f\u5b9e\u9a8c\u3002<\/span><\/p>\n

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\"\u901f\u9012<\/p>\n

\u25b2\u8f89\u745e\u75ab\u82d7\u7814\u53d1\u90e8\u4e3b\u4efb\u3001\u9ad8\u7ea7\u526f\u603b\u88c1Kathrin U. Jansen\u535a\u58eb\uff08\u56fe\u7247\u6765\u6e90\uff1a\u8f89\u745e\u5b98\u65b9\u7f51\u7ad9\uff09<\/span><\/strong><\/p>\n


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\u8f89\u745e\u75ab\u82d7\u7814\u53d1\u90e8\u4e3b\u4efb\uff0c\u9ad8\u7ea7\u526f\u603b\u88c1Kathrin U. Jansen\u535a\u58eb\u8bf4\uff1a\u201c\u8f89\u745e\u671f\u5f85\u4fdd\u6301\u4e0eFDA\u5bf9\u8bdd\uff0c\u4ee5\u671f\u52a0\u5feb\u8fd9\u4e00\u65b0\u4e00\u4ee3\uff0c\u9002\u7528\u4e8e\u6210\u4eba\u768420vPnC\u5019\u9009\u75ab\u82d7\u7684\u5f00\u53d1\u8ba1\u5212\u3002\u5168\u7403\u4fdd\u5065\u884c\u4e1a\u4ecd\u7136\u9700\u8981\u9632\u62a4\u624b\u6bb5\uff0c\u4ee5\u907f\u514d\u80ba\u708e\u94fe\u7403\u83cc\u5f15\u8d77\u7684\u4fb5\u88ad\u6027\u75be\u75c5\u548c\u80ba\u708e\u7684\u6f5c\u5728\u7834\u574f\u6027\u5f71\u54cd\u3002\u6211\u4eec\u5c06\u57fa\u4e8e\u8fd9\u6b3e\u5019\u9009\u75ab\u82d7\u7ee7\u7eed\u79ef\u7d2f\u5728\u5076\u8054\u75ab\u82d7\u65b9\u9762\u7684\u4e13\u957f\u3002\u201d<\/span><\/p>\n


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\u53c2\u8003\u8d44\u6599\uff1a<\/span><\/p>\n

[1]. Pfizer Granted FDA Breakthrough Therapy Designation for 20-Valent Pneumococcal Conjugate Vaccine for the Prevention of Invasive Disease and Pneumonia in Adults Aged 18 Years and Older. Retrieved September 20, 2018, from https:\/\/www.pfizer.com\/news\/press-release\/press-release-detail\/pfizer_granted_fda_breakthrough_therapy_designation_for_20_valent_pneumococcal_conjugate_vaccine_for_the_prevention_of_invasive_disease_and_pneumonia_in_adults_aged_18_years_and_older<\/span><\/p>\n

[2]. Streptococcus <\/span>pneumoniae<\/span>. Retrieved September <\/span>20\uff0c<\/span>2018, from https:\/\/www.cdc.gov\/pneumococcal\/clinicians\/streptococcus-pneumoniae.html <\/span><\/p>\n

[3]. \u5c0f\u75ab\u82d7\u5927\u5e02\u573a\uff0c\u65b0\u578b\u75ab\u82d7\u7814\u53d1\u5e73\u53f0\u4eca\u65e5\u83b74\u4ebfB\u8f6e\u6295\u8d44. Retrieved September 20, 2018, from https:\/\/mp.weixin.qq.com\/s\/8Ais2TxG14W4rfD4XzHo0g<\/span><\/p>\n

[4]. Pneumococcal vaccine. Retrieved September 20, 2018, from https:\/\/www2a.cdc.gov\/nip\/isd\/ycts\/mod1\/courses\/genrec\/10351.asp?seg=H<\/span><\/p>\n

[5]. WHO Model List of Essential Medicines. Retrieved September 20, 2018, from http:\/\/www.who.int\/medicines\/publications\/essentialmedicines\/EML_2015_FINAL_amended_NOV2015.pdf?ua=1<\/span><\/p>\n


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\u672c\u6587\u6765\u81ea\u836f\u660e\u5eb7\u5fb7\u5fae\u4fe1\u56e2\u961f\uff0c\u6b22\u8fce\u8f6c\u53d1\u5230\u670b\u53cb\u5708\uff0c\u8c22\u7edd\u8f6c\u8f7d\u5230\u5176\u4ed6\u5e73\u53f0\uff1b\u5982\u6709\u5f00\u8bbe\u767d\u540d\u5355\u9700\u6c42\uff0c\u8bf7\u5728\u6587\u7ae0\u5e95\u90e8\u7559\u8a00\uff1b\u5982\u6709\u5176\u4ed6\u5408\u4f5c\u9700\u6c42\uff0c\u8bf7\u8054\u7cfbwuxi_media@wuxiapptec.com<\/span>
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