{"id":49105,"date":"2018-09-19T01:00:00","date_gmt":"2018-09-26T01:55:18","guid":{"rendered":"http:\/\/www.05921.net\/index.php\/2018\/09\/26\/%e9%80%9f%e9%80%92-%e8%82%9d%e8%84%8f%e8%84%82%e8%82%aa%e9%99%8d%e4%bd%8e50%ef%bc%8c%e8%84%82%e8%82%aa%e8%82%9d%e6%96%b0%e8%8d%af%e4%b8%b4%e5%ba%8a2%e6%9c%9f%e7%bb%93%e6%9e%9c%e7%a7%af%e6%9e%81\/"},"modified":"2018-09-26T09:55:19","modified_gmt":"2018-09-26T01:55:19","slug":"%e9%80%9f%e9%80%92-%e8%82%9d%e8%84%8f%e8%84%82%e8%82%aa%e9%99%8d%e4%bd%8e50%ef%bc%8c%e8%84%82%e8%82%aa%e8%82%9d%e6%96%b0%e8%8d%af%e4%b8%b4%e5%ba%8a2%e6%9c%9f%e7%bb%93%e6%9e%9c%e7%a7%af%e6%9e%81","status":"publish","type":"post","link":"https:\/\/www.05921.net\/index.php\/49105\/","title":{"rendered":"\u901f\u9012 | \u809d\u810f\u8102\u80aa\u964d\u4f4e>50%\uff0c\u8102\u80aa\u809d\u65b0\u836f\u4e34\u5e8a2\u671f\u7ed3\u679c\u79ef\u6781"},"content":{"rendered":"
\n

\u258e\u836f\u660e<\/span><\/strong>\u5eb7\u5fb7\/\u62a5\u9053<\/span><\/strong><\/strong><\/span><\/strong><\/strong><\/span><\/strong><\/strong><\/strong><\/span><\/strong><\/strong><\/span><\/strong><\/strong><\/h1>\n

\u4eca\u65e5\uff0cViking Therapeutics\u516c\u53f8\u5ba3\u5e03\uff0c\u8be5\u516c\u53f8\u7684\u521b\u65b0\u7597\u6cd5VK2809\uff0c\u5728\u6cbb\u7597\u975e\u9152\u7cbe\u6027\u8102\u80aa\u6027\u809d\u75c5\uff08NAFLD\uff09\u548c\u4f4e\u5bc6\u5ea6\u8102\u86cb\u767d\u80c6\u56fa\u9187\uff08LDL-C\uff09\u5347\u9ad8\u60a3\u8005\u7684\u4e34\u5e8a2\u671f\u8bd5\u9a8c\u4e2d\uff0c\u8fbe\u5230\u4e86\u8bd5\u9a8c\u7684\u4e3b\u8981\u7ec8\u70b9\u548c\u6b21\u8981\u7ec8\u70b9\u3002<\/strong>\u63a5\u53d7VK2809\u6cbb\u7597\u7684\u60a3\u8005\u4e0d\u4f46LDL-C\u6c34\u5e73\u663e\u8457\u964d\u4f4e\uff0c\u800c\u4e14\u809d\u810f\u8102\u80aa\u6c34\u5e73\u4e5f\u83b7\u5f97\u663e\u8457\u964d\u4f4e\u3002<\/span><\/p>\n


<\/span><\/p>\n

\"\u901f\u901250%\uff0c\u8102\u80aa\u809d\u65b0\u836f\u4e34\u5e8a2\u671f\u7ed3\u679c\u79ef\u6781” title=”\u901f\u9012 | \u809d\u810f\u8102\u80aa\u964d\u4f4e>50%\uff0c\u8102\u80aa\u809d\u65b0\u836f\u4e34\u5e8a2\u671f\u7ed3\u679c\u79ef\u6781” \/><\/p>\n

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<\/p>\n

NAFLD\u548c\u975e\u9152\u7cbe\u6027\u8102\u80aa\u6027\u809d\u708e\uff08NASH\uff09\uff0c\u6307\u7684\u662f\u9152\u7cbe\u4ee5\u5916\uff0c\u7531\u5176\u5b83\u56e0\u7d20\u5bfc\u81f4\u7684\u809d\u7ec6\u80de\u5185\u8102\u80aa\u8fc7\u5ea6\u6c89\u79ef\u800c\u5bfc\u81f4\u7684\u75c5\u7406\u7efc\u5408\u5f81\u3002NASH\u662f\u4e00\u79cd\u66f4\u4e25\u91cd\u7684NAFLD\uff0c\u4f1a\u5bfc\u81f4\u809d\u810f\u80bf\u80c0\u548c\u635f\u4f24\u3002\u968f\u7740\u80a5\u80d6\u75c7\u548c\u5176\u5b83\u4ee3\u8c22\u7efc\u5408\u5f81\u7684\u6d41\u884c\uff0cNAFLD\u548cNASH\u5df2\u7ecf\u6210\u4e3a\u53d1\u8fbe\u56fd\u5bb6\u548c\u53d1\u5c55\u4e2d\u56fd\u5bb6\u5bcc\u88d5\u5730\u533a\u6162\u6027\u809d\u75c5\u7684\u9996\u8981\u539f\u56e0\u4e4b\u4e00\u3002\u60a3\u8005\u51fa\u73b0\u809d\u786c\u5316\u7684\u98ce\u9669\u589e\u52a0\u3002\u76ee\u524d\u9664\u4e86\u6539\u53d8\u751f\u6d3b\u4e60\u60ef\u548c\u6cbb\u7597\u9ad8\u80c6\u56fa\u9187\u4ee5\u5916\uff0c\u60a3\u8005\u4eec\u5e76\u6ca1\u6709\u4e00\u6b3e\u83b7\u5f97FDA\u6279\u51c6\u7684\u7597\u6cd5\u53ef\u4ee5\u63a7\u5236\u4ed6\u4eec\u7684\u75c5\u60c5\u3002<\/span><\/p>\n


<\/p>\n

Viking\u516c\u53f8\u5f00\u53d1\u7684VK2809\u662f\u4e00\u79cd\u521b\u65b0\u53e3\u670d\u7532\u72b6\u817a\u6fc0\u7d20\u53d7\u4f53\u03b2\uff08TR\u03b2\uff09\u7684\u5c0f\u5206\u5b50\u6fc0\u52a8\u5242\u3002\u5b83\u4e0d\u4f46\u5bf9TR\u03b2\u6709\u7279\u5f02\u6027\uff0c\u800c\u4e14\u5bf9\u809d\u810f\u7ec4\u7ec7\u4e5f\u5177\u6709\u7279\u5f02\u6027\u3002<\/strong>\u7532\u72b6\u817a\u6fc0\u7d20\u5728\u964d\u4f4e\u4f53\u91cd\uff0c\u8c03\u8282\u8102\u7c7b\u4ee3\u8c22\uff0c\u548c\u4eba\u4f53\u751f\u957f\u7b49\u65b9\u9762\u6709\u91cd\u8981\u4f5c\u7528\u3002VK2809\u9776\u5411\u809d\u810f\u7684\u7279\u6027\u80fd\u591f\u5728\u6cbb\u7597NAFLD\u548c\u9ad8\u80c6\u56fa\u9187\u8840\u75c7\u540c\u65f6\uff0c\u51cf\u5c11\u6216\u6d88\u9664\u5728\u809d\u810f\u5916\u6fc0\u6d3b\u7532\u72b6\u817a\u6fc0\u7d20\u53d7\u4f53\u5e26\u6765\u7684\u526f\u4f5c\u7528\u3002<\/span><\/p>\n


<\/span><\/p>\n

\"\u901f\u901250%\uff0c\u8102\u80aa\u809d\u65b0\u836f\u4e34\u5e8a2\u671f\u7ed3\u679c\u79ef\u6781” title=”\u901f\u9012 | \u809d\u810f\u8102\u80aa\u964d\u4f4e>50%\uff0c\u8102\u80aa\u809d\u65b0\u836f\u4e34\u5e8a2\u671f\u7ed3\u679c\u79ef\u6781” \/><\/p>\n

<\/span>\u25b2\u7532\u72b6\u817a\u6fc0\u7d20\u53d7\u4f53\u6fc0\u6d3b\u7684\u91cd\u8981\u6b65\u9aa4\uff08\u56fe\u7247\u6765\u6e90\uff1aViking Therapeutics\u516c\u53f8\u5b98\u7f51\uff09<\/span><\/strong><\/p>\n


<\/span><\/p>\n

\u5728\u8fd9\u9879\u968f\u673a\u53cc\u76f2\uff0c\u542b\u5b89\u6170\u5242\u5bf9\u7167\u7684\u5e73\u884c\u4e34\u5e8a2\u671f\u8bd5\u9a8c\u4e2d\uff0c\u603b\u8ba145\u540dNAFLD\u6216LDL-C\u6c34\u5e73\u5347\u9ad8\u7684\u60a3\u8005\u88ab\u5206\u4e3a\u4e09\u7ec4\uff0c\u5206\u522b\u63a5\u53d7\u4e86\u5b89\u6170\u5242\u548c\u4e24\u79cd\u4e0d\u540c\u5242\u91cf\u7684VK2809\u7684\u6cbb\u7597\u3002\u8bd5\u9a8c\u7ed3\u679c\u8868\u660e\uff0c\u63a5\u53d7VK2809\u6cbb\u7597\u7684\u60a3\u8005LDL-C\u6c34\u5e73\u964d\u4f4e\u5e45\u5ea6\u663e\u8457\u589e\u52a0\uff0c\u4e0e\u5bf9\u7167\u7ec4\u76f8\u6bd4\u589e\u52a0\u4e8620%\u4ee5\u4e0a<\/strong>\u3002\u800c\u4e14\uff0cVK2809\u60a3\u8005\u7ec4\u5728\u5176\u5b83\u8102\u7c7b\u6307\u6807\u4e0a\u4e5f\u8868\u73b0\u51fa\u663e\u8457\u6539\u5584\u3002<\/span><\/p>\n


<\/span><\/p>\n

\u540c\u65f6\uff0c\u63a5\u53d7VK2809\u6cbb\u7597\u7684\u60a3\u8005\u809d\u810f\u8102\u80aa\u5e73\u5747\u6c34\u5e73\u4e0b\u964d\u4e8657%-60%\u300277%-91%\u63a5\u53d7VK2809\u6cbb\u7597\u7684\u60a3\u8005\u809d\u810f\u8102\u80aa\u6c34\u5e73\u4e0b\u964d\u5e45\u5ea6\u8d85\u8fc7\u4e8630%<\/strong>\u3002 <\/span><\/p>\n

\"\u901f\u901250%\uff0c\u8102\u80aa\u809d\u65b0\u836f\u4e34\u5e8a2\u671f\u7ed3\u679c\u79ef\u6781” title=”\u901f\u9012 | \u809d\u810f\u8102\u80aa\u964d\u4f4e>50%\uff0c\u8102\u80aa\u809d\u65b0\u836f\u4e34\u5e8a2\u671f\u7ed3\u679c\u79ef\u6781” \/><\/p>\n

<\/span>\u25b2\u60a3\u8005\u809d\u810f\u8102\u80aa\u6c34\u5e73\u4e0b\u964d\u6570\u636e\uff08\u56fe\u7247\u6765\u6e90\uff1aViking Therapeutics\u516c\u53f8\u5b98\u7f51\uff09<\/span><\/strong><\/p>\n


<\/p>\n

\u201cVK2809\u5728\u8fd9\u9879\u7814\u7a76\u4e2d\u8868\u73b0\u51fa\u7684\u521d\u6b65\u7597\u6548\u548c\u5b89\u5168\u6027\u6570\u636e\u8ba9\u6211\u4eec\u975e\u5e38\u9f13\u821e\uff0c\u201dViking\u516c\u53f8\u7684CEO Brian Lian\u535a\u58eb\u8bf4\uff1a\u201c\u6211\u4eec\u76f8\u4fe1VK2809\u662f\u2018best-in-class\u2019\u7684NASH\u7597\u6cd5\uff0c\u672c\u6b21\u8bd5\u9a8c\u4e2dVK2809\u5728\u964d\u4f4e\u809d\u810f\u8102\u80aa\u6c34\u5e73\u4e0a\u7684\u8868\u73b0\u652f\u6301\u6211\u4eec\u7684\u89c2\u70b9\u3002\u57fa\u4e8e\u5df2\u53d1\u8868\u7684\u591a\u9879\u7814\u7a76\u6570\u636e\uff0c\u6211\u4eec\u9884\u8ba1\u8fd9\u79cd\u6c34\u5e73\u7684\u809d\u810f\u8102\u80aa\u51cf\u5c11\u4f1a\u5e26\u6765\u957f\u671f\u7ec4\u7ec7\u5b66\u76ca\u5904\u3002\u800c\u4e14\uff0c\u8fd9\u9879\u7814\u7a76\u4e2d\u89c2\u5bdf\u5230\u7684\u8102\u7c7b\u6307\u6807\u6539\u5584\u610f\u5473\u7740\u5b83\u53ef\u80fd\u5bf9\u5fc3\u8840\u7ba1\u5065\u5eb7\u6709\u76ca\u3002\u5bf9\u4e8e\u8fd9\u4e00\u60a3\u8005\u7fa4\u4f53\u6765\u8bf4\uff0c\u8fd9\u662f\u4e00\u4e2a\u91cd\u8981\u7684\u8003\u91cf\u56e0\u7d20\u3002\u6211\u4eec\u671f\u5f85\u8fdb\u4e00\u6b65\u63a8\u52a8VK2809\u5728NASH\u9886\u57df\u7684\u7814\u53d1\u3002\u201d<\/span><\/p>\n


<\/p>\n

\u53c2\u8003\u8d44\u6599\uff1a<\/span><\/p>\n

[1] Viking Therapeutics Announces Positive Top-Line Results from Phase 2 Study of VK2809 in Patients with Non-Alcoholic Fatty Liver Disease (NAFLD) and Elevated LDL-Cholesterol. Retrieved September 18, 2018, from https:\/\/www.prnewswire.com\/news-releases\/viking-therapeutics-announces-positive-top-line-results-from-phase-2-study-of-vk2809-in-patients-with-non-alcoholic-fatty-liver-disease-nafld-and-elevated-ldl-cholesterol-300714176.html<\/span><\/p>\n

 [2] Viking Therapeutics. Retrieved September 18, 2018, from https:\/\/www.vikingtherapeutics.com\/<\/span><\/p>\n


<\/span><\/p>\n

\u672c\u6587\u6765\u81ea\u836f\u660e\u5eb7\u5fb7\u5fae\u4fe1\u56e2\u961f\uff0c\u6b22\u8fce\u8f6c\u53d1\u5230\u670b\u53cb\u5708\uff0c\u8c22\u7edd\u8f6c\u8f7d\u5230\u5176\u4ed6\u5e73\u53f0\uff1b\u5982\u6709\u5f00\u8bbe\u767d\u540d\u5355\u9700\u6c42\uff0c\u8bf7\u5728\u6587\u7ae0\u5e95\u90e8\u7559\u8a00\uff1b\u5982\u6709\u5176\u4ed6\u5408\u4f5c\u9700\u6c42\uff0c\u8bf7\u8054\u7cfbwuxi_media@wuxiapptec.com<\/span>
<\/p>\n


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\n<\/p><\/div>\n","protected":false},"excerpt":{"rendered":"

\u258e\u836f\u660e\u5eb7\u5fb7\/\u62a5\u9053 \u4eca\u65e5\uff0cViking Therapeutics\u516c\u53f8\u5ba3\u5e03\uff0c\u8be5\u516c\u53f8\u7684\u521b\u65b0\u7597\u6cd5VK2809\uff0c\u5728\u6cbb\u7597\u975e […]<\/p>\n","protected":false},"author":1,"featured_media":49106,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[2],"tags":[],"_links":{"self":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/49105"}],"collection":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/comments?post=49105"}],"version-history":[{"count":1,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/49105\/revisions"}],"predecessor-version":[{"id":49110,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/49105\/revisions\/49110"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/media\/49106"}],"wp:attachment":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/media?parent=49105"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/categories?post=49105"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/tags?post=49105"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}