{"id":49137,"date":"2018-09-18T01:00:00","date_gmt":"2018-09-26T01:55:40","guid":{"rendered":"http:\/\/www.05921.net\/index.php\/2018\/09\/26\/%e4%b8%80%e6%ac%a1%e6%b2%bb%e7%96%97%e5%8f%af%e9%a2%84%e9%98%b2%e4%b8%89%e4%b8%aa%e6%9c%88%e5%81%8f%e5%a4%b4%e7%97%9b%ef%bc%8cteva%e6%96%b0%e8%8d%af%e8%8e%b7fda%e6%89%b9%e5%87%86\/"},"modified":"2018-09-26T09:55:41","modified_gmt":"2018-09-26T01:55:41","slug":"%e4%b8%80%e6%ac%a1%e6%b2%bb%e7%96%97%e5%8f%af%e9%a2%84%e9%98%b2%e4%b8%89%e4%b8%aa%e6%9c%88%e5%81%8f%e5%a4%b4%e7%97%9b%ef%bc%8cteva%e6%96%b0%e8%8d%af%e8%8e%b7fda%e6%89%b9%e5%87%86","status":"publish","type":"post","link":"https:\/\/www.05921.net\/index.php\/49137\/","title":{"rendered":"\u4e00\u6b21\u6cbb\u7597\u53ef\u9884\u9632\u4e09\u4e2a\u6708\u504f\u5934\u75db\uff0cTeva\u65b0\u836f\u83b7FDA\u6279\u51c6"},"content":{"rendered":"
\n

\u258e\u836f\u660e<\/span><\/strong>\u5eb7\u5fb7\/\u62a5\u9053<\/span><\/strong><\/strong><\/strong><\/strong><\/span><\/strong><\/strong><\/p>\n


<\/span><\/strong><\/strong><\/strong><\/strong><\/span><\/strong><\/strong><\/p>\n

\u65e5\u524d\uff0c\u68af\u74e6\uff08Teva Pharmaceutical Industries\uff09\u516c\u53f8\u5ba3\u5e03\uff0c\u7f8e\u56fdFDA\u6279\u51c6\u8be5\u516c\u53f8\u7684Ajovy\uff08fremanezumab-vfrm\uff09\u4f5c\u4e3a\u6cbb\u7597\u6210\u4eba\u504f\u5934\u75db\u7684\u9884\u9632\u6027\u7597\u6cd5\u3002<\/strong>Ajovy\u662f\u4e00\u79cd\u4eba\u6e90\u5316\u7684CGRP\u5355\u514b\u9686\u6297\u4f53\u3002\u60a3\u8005\u53ef\u4ee5\u901a\u8fc7\u6bcf\u6708\u6ce8\u5c04\u4e00\u6b21\u6216\u8005\u6bcf\u4e09\u4e2a\u6708\u6ce8\u5c04\u4e00\u6b21Ajovy\u6765\u9884\u9632\u504f\u5934\u75db\u7684\u53d1\u4f5c\u3002<\/strong><\/span><\/p>\n


<\/strong><\/span><\/p>\n

\"\u4e00\u6b21\u6cbb\u7597\u53ef\u9884\u9632\u4e09\u4e2a\u6708\u504f\u5934\u75db\uff0cTeva\u65b0\u836f\u83b7FDA\u6279\u51c6\"<\/p>\n

<\/span>
<\/p>\n

\u504f\u5934\u75db\u901a\u5e38\u5728\u5934\u90e8\u7684\u4e00\u4fa7\u5bfc\u81f4\u4e25\u91cd\u75bc\u75db\uff0c\u540c\u65f6\u9020\u6210\u6076\u5fc3\u3001\u5455\u5410\u3001\u548c\u5bf9\u58f0\u5149\u654f\u611f\u7b49\u75c7\u72b6\u3002\u636e\u7edf\u8ba1\uff0c\u5168\u4e16\u754c\u67093600\u4e07\u4eba\u53d7\u5230\u504f\u5934\u75db\u56f0\u6270\uff0c\u670954%\u7684\u60a3\u8005\u56e0\u4e3a\u75bc\u75db\u975e\u5e38\u4e25\u91cd\uff0c\u53ea\u80fd\u5367\u5e8a\u4e0d\u8d77\uff0c\u5bf9\u4ed6\u4eec\u7684\u751f\u6d3b\u8d28\u91cf\u548c\u5de5\u4f5c\u80fd\u529b\u9020\u6210\u4e25\u91cd\u7684\u5f71\u54cd\u3002\u4ed6\u4eec\u6025\u9700\u521b\u65b0\u7597\u6cd5\u9884\u9632\u504f\u5934\u75db\u7684\u53d1\u4f5c\u3002<\/span><\/p>\n


<\/p>\n

\"\u4e00\u6b21\u6cbb\u7597\u53ef\u9884\u9632\u4e09\u4e2a\u6708\u504f\u5934\u75db\uff0cTeva\u65b0\u836f\u83b7FDA\u6279\u51c6\"<\/p>\n

\u25b2<\/span><\/strong>54%\u60a3\u8005\u504f\u5934\u75db\u53d1\u4f5c\u65f6\u9700\u8981\u5367\u5e8a\u4f11\u606f\uff08\u56fe\u7247\u6765\u6e90\uff1a\u68af\u74e6\u516c\u53f8\u63d0\u4f9b\uff09<\/span><\/strong><\/p>\n


<\/span><\/p>\n

Ajovy\u662f\u68af\u74e6\u516c\u53f8\u5f00\u53d1\u7684\u521b\u65b0\u504f\u5934\u75db\u9884\u9632\u7597\u6cd5\u3002\u5b83\u662f\u4eba\u6e90\u5316\u7684CGRP\u5355\u514b\u9686\u6297\u4f53\uff0c\u901a\u8fc7\u4e0eCGRP\u76f8\u7ed3\u5408\uff0c\u53ef\u4ee5\u963b\u65adCGRP\u4e0e\u5b83\u7684\u53d7\u4f53\u7ed3\u5408\uff0c\u4ece\u800c\u8d77\u5230\u9884\u9632\u504f\u5934\u75db\u7684\u4f5c\u7528\u3002Ajovy\u6709\u4e24\u79cd\u5242\u91cf\uff0c225 mg\u7684\u5242\u91cf\u9700\u8981\u60a3\u8005\u6bcf\u6708\u6ce8\u5c04\u4e00\u6b21\uff0c\u800c675 mg\u7684\u5242\u91cf\u53ea\u9700\u8981\u60a3\u8005\u6bcf\u4e09\u4e2a\u6708\u6ce8\u5c04\u4e00\u6b21\u5c31\u53ef\u4ee5\u8fbe\u5230\u9884\u9632\u504f\u5934\u75db\u53d1\u4f5c\u7684\u6548\u679c\u3002<\/span><\/p>\n


<\/span><\/p>\n

\"\u4e00\u6b21\u6cbb\u7597\u53ef\u9884\u9632\u4e09\u4e2a\u6708\u504f\u5934\u75db\uff0cTeva\u65b0\u836f\u83b7FDA\u6279\u51c6\"<\/p>\n

<\/span>\u25b2Ajovy\uff08\u56fe\u7247\u6765\u6e90\uff1a\u68af\u74e6\u516c\u53f8\u63d0\u4f9b\uff09<\/strong><\/span><\/strong><\/p>\n


<\/p>\n

\u8fd9\u6b21\u6279\u51c6\u662f\u57fa\u4e8e\u4e24\u9879\u542b\u5b89\u6170\u5242\u7684\u4e34\u5e8a3\u671f\u8bd5\u9a8c\uff0c\u5728\u8fd9\u4e9b\u8bd5\u9a8c\u4e2d\uff0c\u5931\u80fd\u6027\u504f\u5934\u75db\uff08disabling migraine\uff09\u60a3\u8005\u63a5\u53d7\u4e86Ajovy\u4f5c\u4e3a\u5355\u4e00\u7597\u6cd5\u6216\u8005Ajovy\u4e0e\u5176\u5b83\u53e3\u670d\u9884\u9632\u7597\u6cd5\u7ec4\u5408\u7684\u6cbb\u7597\u3002\u8bd5\u9a8c\u7ed3\u679c\u8868\u660e\uff0c\u5728\u4e3a\u671f12\u5468\u7684\u8bd5\u9a8c\u8fc7\u7a0b\u4e2d\uff0c\u60a3\u8005\u6bcf\u6708\u51fa\u73b0\u504f\u5934\u75db\u7684\u65e5\u5b50\u83b7\u5f97\u663e\u8457\u51cf\u5c11\u3002<\/span><\/p>\n


<\/p>\n

Ajovy\u4e34\u5e8a3\u671f\u9879\u76ee\u7684\u9996\u5e2d\u7814\u7a76\u5458\uff0c\u6258\u9a6c\u65af\u6770\u6590\u900a\u5927\u5b66\u533b\u9662\u7684Stephen Silberstein\u535a\u58eb\u8bf4\uff1a\u201c\u5927\u7ea640%\u7684\u504f\u5934\u75db\u60a3\u8005\u53ef\u80fd\u4ece\u9884\u9632\u6027\u7597\u6cd5\u4e2d\u83b7\u76ca<\/strong>\uff0c\u7136\u800c\u5176\u4e2d\u5927\u90e8\u5206\u4eba\u6ca1\u6709\u63a5\u53d7\u6cbb\u7597\u3002\u6211\u975e\u5e38\u9ad8\u5174\u6211\u4eec\u80fd\u591f\u4e3a\u60a3\u8005\u63d0\u4f9b\u4e00\u79cd\u65b0\u6cbb\u7597\u9009\u62e9\uff0c\u8ba9\u4ed6\u4eec\u6bcf\u6708\u504f\u5934\u75db\u53d1\u4f5c\u7684\u65e5\u5b50\u51cf\u5c11\u3002\u201d<\/span><\/p>\n


<\/p>\n

\u53c2\u8003\u8d44\u6599\uff1a<\/span><\/p>\n

[1] Teva Announces U.S. Approval of AJOVYTM (<\/span>fremanezumab<\/span>–<\/span>vfrm<\/span>) Injection, the First and Only Anti-CGRP Treatment with Both Quarterly and Monthly Dosing for the Preventive Treatment of <\/span>Migraine<\/span> in Adults. Retrieved September 17, 2018, from  https:\/\/www.businesswire.com\/news\/home\/20180914005613\/en\/Teva-Announces-U.S.-Approval-AJOVYTM-fremanezumab-vfrm-Injection <\/span><\/p>\n

[2] <\/span>Migraine<\/span>. Retrieved September 17, 2018, from https:\/\/www.mayoclinic.org\/diseases-conditions\/migraine-headache\/symptoms-causes\/syc-20360201<\/span><\/p>\n


<\/p>\n

\u672c\u6587\u6765\u81ea\u836f\u660e\u5eb7\u5fb7\u5fae\u4fe1\u56e2\u961f\uff0c\u6b22\u8fce\u8f6c\u53d1\u5230\u670b\u53cb\u5708\uff0c\u8c22\u7edd\u8f6c\u8f7d\u5230\u5176\u4ed6\u5e73\u53f0\uff1b\u5982\u6709\u5f00\u8bbe\u767d\u540d\u5355\u9700\u6c42\uff0c\u8bf7\u5728\u6587\u7ae0\u5e95\u90e8\u7559\u8a00\uff1b\u5982\u6709\u5176\u4ed6\u5408\u4f5c\u9700\u6c42\uff0c\u8bf7\u8054\u7cfbwuxi_media@wuxiapptec.com<\/span>
<\/p>\n


<\/span><\/p>\n

\n<\/p><\/div>\n","protected":false},"excerpt":{"rendered":"

\u258e\u836f\u660e\u5eb7\u5fb7\/\u62a5\u9053 \u65e5\u524d\uff0c\u68af\u74e6\uff08Teva Pharmaceutical Industries\uff09\u516c\u53f8\u5ba3\u5e03\uff0c\u7f8e\u56fdFD […]<\/p>\n","protected":false},"author":1,"featured_media":49138,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[2],"tags":[],"_links":{"self":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/49137"}],"collection":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/comments?post=49137"}],"version-history":[{"count":1,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/49137\/revisions"}],"predecessor-version":[{"id":49142,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/49137\/revisions\/49142"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/media\/49138"}],"wp:attachment":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/media?parent=49137"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/categories?post=49137"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/tags?post=49137"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}